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1

Auvil, James D. "News about Dental Prophylaxis." Journal of Veterinary Dentistry 7, no. 3 (1990): 14–15. http://dx.doi.org/10.1177/089875649000700301.

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The most important measure in the treatment of inflammation of the gums is the removal of the concretions from the teeth, and next the arousing in the mind of the patient an active determination to keep them clean in the future. These two measures are absolutely necessary for success; nothing can be accomplished unless they are scrupulously carried out. The removal of these concretions in such a manner as to assure success is, however, one of the most difficult operations in dental surgery. Another very serious difficulty standing in the way of success is the very slack and inefficient notions that have been held in regard to it by the profession at large. When dentists learn to regard this operation as equal in importance to, and requiring as much thoroughness as, the filling of teeth, and when they apply themselves with the same diligence to acquiring the necessary dexterity in its performance, they will be rewarded with success; without this, success in the treatment of this disease cannot be attained.
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2

Coulter, W. A., A. Coffey, I. D. F. Saunders, and A. M. Emmerson. "Bacteremia in Children Following Dental Extraction." Journal of Dental Research 69, no. 10 (1990): 1691–95. http://dx.doi.org/10.1177/00220345900690101201.

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The incidence and intensity of bacteremia following tooth extraction in children were measured by blood culture. The effects on bacteremia of the number and type of teeth extracted, oral hygiene, gingival health, presence of abscess, and antibiotic prophylaxis were assessed. Antibiotic prophylaxis reduced the incidence of bacteremia from 63% to 35%. The intensity of bacteremia was 2 cfu/mL of blood or less in 80% of the children. An agar pour-plate method of blood culture was significantly more effective than broth in culturing the small volumes of inoculum. Of 83 bacterial strains characterized, 39 were strict anaerobes or micro-aerophilic, and the remainder mainly streptococci. S. mitior and S. sanguis were most commonly isolated, often in pure culture, and were generally sensitive to antibiotics. No direct association was demonstrated between the plaque and gingival indices and incidence of bacteremia or between the number of teeth extracted and the incidence or intensity of bacteremia. It is concluded that all children at risk from infective endocarditis require antibiotic prophylaxis prior to tooth extraction, since it is impossible for the likelihood or intensity of transient bacteremia to be clinically predicted.
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3

Sreenivasan, Prem K., and Kakarla V. V. Prasad. "Distribution of dental plaque and gingivitis within the dental arches." Journal of International Medical Research 45, no. 5 (2017): 1585–96. http://dx.doi.org/10.1177/0300060517705476.

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Objective The natural accumulation of supragingival plaque on surfaces of human teeth is associated with gingival inflammation and the initiation of common oral diseases. This study evaluated the distribution of dental plaque and gingivitis scores within the dental arches after prophylaxis. Methods Adult subjects from the Dharwad, India area representing the general population who provided written informed consent were scheduled for screening. Healthy subjects over the age of 18 years, not currently requiring any medical or dental care, and presenting with a complement of at least 20 natural teeth were recruited for this parallel design study. Enrolled subjects (n = 41) underwent oral examinations for dental plaque (PI) and gingivitis (GI) using the Turesky modification of the Quigley-Hein and the Löe-Silness Index, respectively, at the baseline visit, followed by a whole mouth dental prophylaxis. Subjects were given fluoride toothpaste for twice daily oral hygiene for the next 30 days. Subjects were recalled on days 15 and 30 for PI and GI examinations identical to baseline. Results Analyses indicated that mean scores for PI and GI on either arch and the whole mouth were higher than 2 and 1, respectively, during all examinations. Anterior surfaces consistently exhibited lower PI scores than posterior regions of either arch, or the entire dentition. Regional GI differences within the dentition were similar to PI scores, with lower scores on anterior than posterior teeth. Prophylaxis reduced both the frequency and mean scores of both PI and GI, irrespective of arch, with lower scores observed on anterior than posterior regions during all recall visits. Molar and lingual regions consistently exhibited higher PI and GI scores compared with anterior surfaces. At all examinations, mean scores for both plaque and gingivitis were higher on approximal vestibular than mid-vestibular surfaces. Conclusions Differences observed in PI and GI within the dentition have several practical implications: (a) there are advantages of whole mouth assessments for oral health (b) a need for oral hygiene formulations to reduce the larger deposits of dental plaque in the posterior region and resultant gingival inflammation, and (c) a requirement for ongoing oral hygiene education.
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4

Wiggs, Robert B., Heidi B. Lobprise, and Mark A. Tholen. "Clinical Evaluation of Sofscale™ Calculus Scaling Gel in Dogs and Cats." Journal of Veterinary Dentistry 11, no. 1 (1994): 9–13. http://dx.doi.org/10.1177/089875649401100105.

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An in-depth study was performed using SofScale™ Calculus Scaling Gel to determine its value in assisting animal dental prophylaxis as compared to non-treated teeth. A total of one hundred and five animals (dogs and cats) were tested. This gel saved a slight amount of time on animal full mouth prophylaxis in many cases, especially in heavy calculus groups. The gel helped to reduce total actual scaling time, but did not reduce actual procedure time.
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5

Fava, Marcelo, Alexandre Viana Frascino, Ivan Balducci, and Carolina Judica Ramos. "Comparative analysis of different prophylatic methods on primary teeth enamel roughness." Brazilian Dental Science 21, no. 3 (2018): 335. http://dx.doi.org/10.14295/bds.2018.v21i3.1567.

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<p><strong>Objective: </strong>The purpose of this study was to perform an experimental quantitative comparison of primary teeth enamel alterations under three commonly prophylaxis surface polishing treatments. <strong>Material and </strong><strong>Methods: </strong>36 healthy primary teeth naturally exfoliated were selected and randomly separated in three groups. Group I was treated with a rotary instrument set at a low speed, rubber cup and a mixture of water and pumice; group II with a rotary instrument set at a low speed, rubber cup and prophylaxis paste Herjos-F (Vigodent S/A Indústria e Comércio, Rio de Janeiro, Brazil); and group III with sodium bicarbonate spray Profi II Ceramic (Dabi Atlante Indústrias Médico Odontológicas Ltda, Ribeirão Preto, Brazil). All procedures were performed by the same operator for ten seconds, and samples were rinsed and stored in distilled water. Pre-and post-treatment surface evaluation was completed using a surface profilometer Mitutoyo SJ400. <strong>Results: </strong>The results of this study were statistically analyzed with the GraphPad PRISM (version 6, 2010). The pumice and water led to significantly rougher surfaces than other groups in Tukey’s test (Group I: 1.22 Ra; Group II 0.38 Ra; Group III: 1.01 Ra). Pre-and post-treatment comparison revealed significantly rougher enamel surface with pumice. <strong>Conclusion: </strong>Based on this study, it can be concluded that there was an increased enamel surface roughness when teeth were treated with pumice and water in comparison to bicarbonate spray and prophylaxis paste.</p><p><strong>Keywords</strong></p><p><strong></strong>Dental enamel; Dental prophylaxis; Jet abrasive system; Enamel roughness; Primary teeth.<strong> <br clear="all" /> </strong></p>
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6

Smagliuk, L. V., and M. I. Dmytrenko. "DISTAL OCCLUSION AND DENTAL CROWDING: TREATMENT STRATEGY." Ukrainian Dental Almanac, no. 2 (June 26, 2020): 103–8. http://dx.doi.org/10.31718/2409-0255.2.2020.16.

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Dental anomalies are the leading ones among dental diseases in the period of mixed (79,96%) and permanent (84,33%) dentition. According to the results of our studies, frequency of distal occlusion (up to 40%) and dental crowding (up to 65%) are the largest in structure of orthodontic pathology.
 The aim of the study is to analyze and summarize knowledge about ways of enhancement of treatment and prophylaxis efficiency in patients with distal occlusion and dental crowding.
 Genetic predisposition, early childhood diseases (including upper respiratory tract infections), children's bad habits, pathological state of teeth (adentia, impaction, micro-, macrodentia), micro-, macrognathia, functional disorders of maxillofacial area contribute a high percentage in structure of "risk factors" which lead to formation of distal occlusion with dental crowding. For each particular patient distal occlusion, complicated by dental crowding, is formed under the influence of combination of several "risk factors", where the first place belongs to disturbances of dental area: breathing, closing of lips, swallowing, chewing, speech.
 Today it is well known that the first step in correction of distal occlusion of dentitions is to evaluate the patient's potential growth. Treatment in the period of mixed dentition is important with relation to protection of palate from trauma by mandibular incisors with a large sagittal gap, prophylaxis of dysfunction of temporomandibular joint, psychological rehabilitation of children during speech formation, as well as to improve the prognosis of treatment in older age. The best period of treatment is a peak of growth and development. Growth is the most important factor in planning treatment of distal occlusion, since dramatic changes in correction are related to growth rather than teeth movement. Orthodontists forbear from recommendations for teeth extraction in growing patients, as they believe that it leads to worsening of face profile and does not allow to achieve optimal relationships of jaw and occlusion.
 In adult patients, complete conservative correction of distal occlusion is possible only in the absence of skeletal disorders. Combined method, namely combination of orthodontic treatment and orthognathic surgery, is an alternative for adults treatment.
 Adequate individual approach to orthodontic treatment in patients with distal occlusion complicated by dental crowding is based on a comprehensive clinical examination, scientific analysis and results interpretation of additional examination methods. Full functional occlusion is possible if all elements of dentition: occlusion, periodontal tissues, temporomandibular joints, muscles and nervous system, are considered. Stable results and positive prognosis are provided by normalization of physiological state of masticatory and mimic muscles.
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7

Gerreth, Karolina, Timucin Ari, Wojciech Bednarz, Michal Nowicki, and Maria Borysewicz-Lewicka. "Dental Health Status and Oral Health Care in Nursery School-Aged Children and their Parents Living in Poznan (Poland)." Medical Principles and Practice 29, no. 3 (2019): 211–18. http://dx.doi.org/10.1159/000503333.

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Objectives: The aim of this study was to evaluate the dental health status of nursery age children and parents. The use of dental services was assessed. Subjects and Methods: The study was performed in nursery schools located in Poznan, Western Poland. Clinical examination was carried out in 157 children (48.41% males and 51.59% females), aged 10–42 months. Dental health status (the number of teeth with caries, fillings and extracted) of their parents was determined on the basis of data obtained from a questionnaire. The questions also concerned information on child’s and parents’ dental check-ups and opinion on their predisposition to dental caries. Results: Clinical examination revealed that 21.05% of boys and 18.51% of girls had dental caries. Most mothers had from 1 to 5 either carious and/or filled teeth (47.13%) or extracted teeth due to carious process (61.15%); the fathers’ values were similar at 46.50 and 66.24%, respectively. More mothers (84.71%) than fathers (72.62%) had regular dental check-ups (p = 0.02). The analysis of mother-father-child triads showed that when both parents visited the dentist regularly, more children were free of caries (56.68%) in comparison to those with the disease (13.38%; p < 0.001). Conclusions: This study showed that the dental health status, as well as oral care of nursery school children and their parents, is unsatisfactory. Therefore, there is a need to introduce an intensive dental educational program focusing on dental prophylaxis for nursery age children and their parents or caregivers.
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8

Allen, U. "Infective Endocarditis: Updated Guidelines." Canadian Journal of Infectious Diseases and Medical Microbiology 21, no. 2 (2010): 74–77. http://dx.doi.org/10.1155/2010/760276.

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The most recent revision of the American Heart Association guidelines on infective endocarditis prophylaxis occurred in 2007. These revisions were based on the fact that current data have brought into question the benefit of previous recommendations for infective endocarditis prophylaxis. It was noted that the bacteremia that occurs following dental procedures represents only a fraction of the episodes of bacteremia that occur with activities of daily living (such as chewing, brushing teeth and other oral hygiene measures). The target groups and the procedures for which prophylaxis is reasonable have been significantly reduced in number. The focus is now on patients who are most likely to have adverse outcomes from infectious endocarditis. The present article is targeted at practicing Canadian physicians and provides the rationale for the current recommendations. In addition to a summary of the indications for prophylaxis, information is provided on the conditions for which prophylaxis is not recommended.
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9

Włoch, Krzysztof, Piotr Książek, Anna Krajewska, and Dorota Rolińska. "Organization of dental care – caries prophylaxis in children and teenagers in Poland." Polish Journal of Public Health 129, no. 2 (2019): 68–71. http://dx.doi.org/10.2478/pjph-2019-0016.

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Abstract Dental caries in children and teenagers is a social problem and an important element in public health. It stems from its high prevalence and the consequences of not implementing proper treatment are serious. Younger and younger children suffer from dental caries. When it is not treated, the consequences tend to be serious and costly. Pathogenesis of dental caries, methods of treatment and its prevention have been described based on available literature. The decline in frequency of its appearance will be beneficial for both the sick and society. It will be possible thanks to an early introduction of caries prophylaxis. What is more, a change of mindset and lifestyle is highly recommended as well, not to mention the fact that full and easy access to dental care seems to be essential. All of the factors mentioned above are strictly connected with the proper organization of dental care providing special treatment for children and teenagers in Poland. Its scale should be wide and should cover such activities like teaching to brush one’s teeth properly, access to fluoridation or treatment provided in public dental surgeries located, for example, on school grounds. Current organization of dental care is dealing better and better with the issue concerned, however, to minimalize the risk of caries in children further changes should be introduced.
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10

Obradovic, Marija, and Olivera Dolic. "Caries prevalence and risk factors for its development in urban and rural regions." Serbian Dental Journal 55, no. 1 (2008): 34–42. http://dx.doi.org/10.2298/sgs0801034o.

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Introduction: Many socio-demographic indicators, apart from other risk factors, may lead to a multicausal disease, such as caries. Aim: The aim of this study was to evaluate dental health status in 12-year olds in urban and rural populations in Banja Luka and determine possible risk factors in their oral health behavior. Subjects and Methods: The study involved 496 children, 12-year-old pupils in primary schools in urban and rural regions of Banja Luka. Dental checkup was performed in classrooms at day light and using dental mirrors and probes. Caries prevalence was analyzed using the Klein-Palmer system to obtain the mean decayed teeth values for the two regions. The pupils filled in questionnaires about their socioeconomic status, motivation and knowledge on oral health as well as oral hygiene and dietary habits. Results: High mean decayed teeth values were obtained in the rural population of pupils (4.89 and 6.74). Questionnaire data showed statistically significant differences regarding dental visits, fluoride prophylaxis, the frequency of tooth brushing and the age when pupils started to maintain oral hygiene. Conclusion: 12-year olds have a large number of affected teeth, especially in the rural region. It is essential to implement oral health education programs aimed at improving oral health and eliminating the misbalance in dental health status in populations living in different socio-economic and demographic regions.
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11

Dholam, Kanchan P., Priyanka Piyush Somani, Seema D. Prabhu, and Shubhangi R. Ambre. "Effectiveness of Fluoride Varnish Application as Cariostatic and Desensitizing Agent in Irradiated Head and Neck Cancer Patients." International Journal of Dentistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/824982.

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Objective. To evaluate the effectiveness of three-month fluoride varnish application on radiation caries and dental sensitivity and to assess compliance to three-month fluoride varnish application.Materials and Methods. 190 irradiated head and neck cancer patients were randomly selected and reviewed retrospectively. Oral prophylaxis, fluoride varnish application, and treatment of dental caries were done prior to radiation therapy. Patients were followed up at every three months for dental evaluation and fluoride varnish application. Decayed-missing-filling-teeth indices, dental sensitivity, and compliance to fluoride varnish application were noted for fifteen months and analyzed statistically.Results. Significant increase in decayed-missing-filling-teeth index was seen at nine(P=0.028), twelve(P=0.003)and fifteen(P=0.002)months follow-up. However, the rate of increase in decayed-missing-filling-teeth indices was 1.64/month which is less than the rate mentioned in the literature (2.5/month). There was no significant effect of sex(P=0.952)and surgery(P=0.672)on radiation caries, but site of disease(P=0.038)and radiation dose(P=0.015)were found to have statistically significant effect. Dental sensitivity decreased from 39% at 3 months to 25% at 15 months followup. 99% compliance to fluoride varnish application was seen till six months followup which decreased to 46% at fifteen months.Conclusion. Three-month fluoride varnish application is effective in decreasing radiation caries and sensitivity and has good compliance.
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12

Biesbrock, Aaron R., Robert D. Bartizek, Patricia A. Walters, Geza T. Terezhalmy, and Julie M. Grender. "A Clinical Evaluation of Extrinsic Stain Removal: A Rotation-Oscillation Power Toothbrush versus a Dental Prophylaxis." Journal of Contemporary Dental Practice 9, no. 5 (2008): 1–8. http://dx.doi.org/10.5005/jcdp-9-5-1.

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Abstract Aim To assess extrinsic stain removal efficacy of a power toothbrush and a dental prophylaxis followed by the use of a standardized American Dental Association (ADA) reference manual toothbrush. Methods and Materials This was a randomized, positive-controlled, examiner-blind, parallel group, twoweek study. A Lobene stain examination was performed at baseline. Subjects were randomized to one of two treatment groups: Group 1: Oral-B® Vitality™ Pro White power toothbrush or Group 2: Subjects receiving a dental prophylaxis then using a standardized ADA reference manual toothbrush. Subjects were instructed to brush their teeth with the assigned toothbrush and a fluoride dentifrice in front of a mirror twice per day for 2 minutes. Stain was reassessed following 2 weeks of brushing. Results A significant reduction (p <0.001) in mean Lobene composite scores after 2 weeks was found for Group 1 (90.6%) and Group 2 (94.4%). Both groups also showed a significant reduction (p <0.001) in extent and intensity scores. There was no significant group difference in reduction in mean Lobene composite scores (p>0.1). Conclusions The Oral-B Vitality Pro White power toothbrush showed effective stain removal at a level similar to receiving an oral prophylaxis followed by the use of an ADA reference manual toothbrush. Clinical Significance In this small study the Oral-B Vitality Pro White power toothbrush achieved statistically significant stain removal between dental visits. Citation Terézhalmy GT, Walters PA, Bartizek RD, Grender JM, Biesbrock AR. A Clinical Evaluation of Extrinsic Stain Removal: A Rotation-Oscillation Power Toothbrush versus a Dental Prophylaxis. J Contemp Dent Pract 2008 July; (9)5:001-008.
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Prisyazhnyuk, Oksana Valentinovna, and A. K. Iordanishvili. "NON-CARIOUS DENTAL LESIONS IN TYPE 2 DIABETES." Russian Journal of Dentistry 23, no. 5 (2019): 208–11. http://dx.doi.org/10.18821/1728-2802-2019-23-5-208-211.

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The article presents an analysis of the results of a study of the incidence of non-carious tooth lesions in adults with type 2 diabetes, including when they were under dynamic observation by a dentist for 2.5-3 years. It was found that in patients with type 2 diabetes mellitus non-carious lesions of the teeth (49.51%) were significantly more likely to occur than in people in the control group (29.13%). At the same time, it has been shown that in people with type 2 diabetes, a significant improvement in dental health can be achieved due to their being under dynamic supervision by a dentist with a 2-time visit during the year. This allows to reduce the incidence of non-carious tooth damage in type 2 diabetes mellitus by 17.7%, mainly due to the constantly implemented secondary and tertiary dental prophylaxis, rational and competent use of individual oral care products by patients, and also due to dental orthopedic treatment.
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Jan, Chowdhury Moin, Mostaque H. Sattar, Mujibur Rahman Howlader, and Kumkum Pervin. "Prophylactic use of cephradine in dental procedures: A observational study in Bangladesh." Bangladesh Journal of Dental Research & Education 5, no. 2 (2015): 49–54. http://dx.doi.org/10.3329/bjdre.v5i2.24716.

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Bacteremia is common with manipulation of the teeth and periodontal tissues during dental procedures. Majority of dental office visits result in some degree of bacteremia that warrants antibiotic prophylaxis before a dental procedure to reduce the frequency, nature or duration of bacteremia. This study aimed to collect data on prophylactic use of cephradine which is most preferred in dental procedures in Bangladesh. A total 2219 of patients both adult and children above 5 years were enrolled to assess use of antibiotic, its dose and duration for antibiotic prophylaxis during dental procedures. Efficacy of antibiotic prophylaxis in terms of clinical cure, further dose modification and need to change antibiotic was evaluated at day 10 of antibiotic use and in case of root canal therapy at day 30. Any side effect of antibiotic use recorded within 3 days was considered for safety evaluation. This was a non-controlled, multicentre, observational study. 2016 (90.9%) of the patients received cephradine as prophylactic antibiotic with a mean dosage of 500mg (487.48+60.99) and duration of treatment was 3-7 days (5.47+1.03). Some of the dentists also preferred amoxicillin (149, 6.7%) and cephalexin (54, 2.4%) for prophylaxis. The majority of the patients (1657, 82.2%) who had prophylaxis with cephradine had no clinical sign of infection and some of the patients needed to change their initial dose or change of the antibiotic. Overall 1816 (81.8%) patients were found having no clinical sign of infection on antibiotic prophylaxis. Among the patients 239 (10.7%) needed to change the dose of prescribed antibiotic and 55 (2.4%) were required to change their prescribed antibiotic. However, the data on type of infection was not recorded. 109 (4.9%) patients were lost to follow up on Day 10. Prescribed antibiotic prophylaxis was not associated with adverse events in majority (91%) of the patients. Some of the patients reported diarrhea (104, 4.7%), stomach upset (68, 3.1%) and dizziness (31, 1.4%) during antibiotic use. However, those were self-limiting and no dose adjustment, discontinuation of therapy or withdrawal from the study was required. No serious adverse events were reported. Cephradine 500 mg for 5 days course was preferred as prophylactic antibiotic in dental procedures in this study. Majority of the patients had no clinical sign of infection on evaluation at day 10. Cephradine therapy was mostly not associated with adverse events in patients; however, diarrhea, stomach upset and dizziness were reported in some patients that were self-limiting.Bangladesh Journal of Dental Research and Education Vol.5(2) 2015: 49-54
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Fonseca, André Manoel Lima da, Inger Campos Tuñas, Fábio Vidal, Fábio Ramôa Pires, and Lucio Souza Gonçalves. "Dental bleaching with and without LED/Laser association: a split-mouth controlled study." Revistas 73, no. 4 (2016): 267. http://dx.doi.org/10.18363/rbo.v73n4.p.267.

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Objective: The aim of this study was to compare dental color changes after a one-session tooth bleaching procedure using 35% hydrogen peroxide with and without hybrid light (LED/diode laser) activation. Material and Methods: 20 volunteers were included in a split-mouth controlled clinical trial. A 35% hydrogen peroxide gel was applied directly on the buccal surface and adjacent areas of all upper anterior teeth. The six teeth were divided into two groups: the upper right incisors and canine were submitted to the tooth bleaching with the gel and the hybrid light (LED/diode laser) while the left incisors and canine were submitted to tooth bleaching with only the gel. Dental color was measured with a visual color scale and a spectrophotometer at five different moments: initial appointment, immediately after prophylaxis, and 14, 30 and 180 days after bleaching. Results: The comparison between the results of both treatments (with and without LED/laser) did not show any statistically significant differences (p > 0.05; Wilcoxon’s test) neither for objective (spectrophotometer) nor for subjective evaluations (visual color scale). Conclusion: The results of the present study showed that there are no differences in dental color changes between dental bleaching with gel and LED/Laser activation and dental bleaching with only gel.
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Gonçalves, Iana M. C., Raíssa M. Garcia, Amanda G. C. de Souza, et al. "Association of Tooth Bleaching and Microabrasion as a Resolution of Intrinsic Staining by Fluorosis: A Case Report." Current Dentistry 2, no. 1 (2020): 78–82. http://dx.doi.org/10.2174/2542579x02999200428093906.

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Background: Different treatment protocols for teeth affected by fluorosis have been applied. Among them, microabrasion associated with tooth bleaching has presented satisfactory results in the treatment of intrinsic and/or extrinsic staining. Case Presentation: A 22-year-old female patient attended the Dental Clinic of FOP/UNICAMP, reporting dissatisfaction with her smile due to the presence of white striations contrasting with the yellowish hue of the other teeth. Initially, the adequacy of the oral environment was performed by supragingival scraping and prophylaxis. Due to the characteristics of the staining, fluorosis TF3, the treatment plan consisted of teeth whitening with 35% hydrogen peroxide (Whiteness HP, AutoMixx 35% FGM) and microabrasion (Whiteness RM, FGM). Conclusion: The association of tooth bleaching and microabrasion techniques provided the harmonization of the smile and resolution of the clinical case of the main complaint.
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Kressin, N. R., U. Boehmer, M. E. Nunn, and A. Spiro. "Increased Preventive Practices Lead to Greater Tooth Retention." Journal of Dental Research 82, no. 3 (2003): 223–27. http://dx.doi.org/10.1177/154405910308200314.

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Prior research has rarely examined the impact of ADA-recommended preventive practices on tooth retention. We hypothesized that better oral hygiene leads to increased tooth retention. We examined the association of cross-sectional and long-term assessments of preventive practices, as well as various combinations of hygiene practices, with tooth retention. Among 736 male participants in the VA Dental Longitudinal Study, we utilized cross-sectional and longitudinal self-reports of toothbrushing, dental floss use, annual prophylaxis, and combinations of such behaviors, and examined their association with clinically assessed numbers of teeth. Baseline and long-term hygiene behaviors (except brushing) were associated with an increased baseline number of teeth and decreased subsequent tooth loss. Use of multiple hygiene behaviors was associated with greater tooth retention, cross-sectionally and longitudinally. Adherence to ADA recommendations for preventive care leads to better oral health, and consistently practicing preventive behaviors over the long term confers greater benefits than doing so over the short term.
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Janković, Svjetlana, Aleksandra Žuža, Bojana Davidović, Ivana Simić, and Lado Davidović. "Traumatic extraction of upper central incisors." Stomatoloski glasnik Srbije 65, no. 2 (2018): 97–104. http://dx.doi.org/10.2478/sdj-2018-0010.

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Summary Introduction Tooth and other oral tissue damage can occur at any time of life. Traumatic extraction is a complex traumatic injury characterized by complete dislodgement of the tooth from its alveolus. The diagnosis of traumatically injured teeth includes X-rays and a detailed clinical examination. Case report A twelve-year-old boy reported at the dental clinic of the Faculty of Medicine due to the injury in the anterior maxillary region. It was a sport injury. The time elapsed since the accident was 2 hours and 20 minutes. According to the clinical examination and X-rays the diagnosis was: The teeth 11 and 21 – Complete traumatic dental avulsion and fracture; 22-Hypodontia and chin contusion and laceration. The teeth were brought in physiological solution. After applying local anesthetic, soft tissue was cleaned, the teeth positioned back in their alveoli and an immobilizing splint of fiberglass fibers placed. The patient was administered antibiotics and recommended tetanus prophylaxis. Seven days after the injury, teeth were treated endodontically. After one month, the immobilizing splint was removed. The tooth 21 was definitely obturated and composite buildups were done on both teeth. Calcium hydroxide dressing was left in the canal of the tooth 11. One month and 3 weeks after the injury, a fistula appeared above the tooth 11, and the treatment was finally completed after seven months. Conclusion Traumatic tooth injuries, of any kind, require urgent treatment as time loss usually reduces chances for successful treatment. One year after the injury, the patient had no symptoms and the result was functional and aesthetically acceptable.
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Zotz, Rainer B., Andrea Gerhardt, and Rudiger E. Scharf. "Successful Use of Recombinant Factor VIIa (rVIIa, NovoSeven) in Two Patients with Bernard Soulier Syndrome and Dental Extraction." Blood 112, no. 11 (2008): 4562. http://dx.doi.org/10.1182/blood.v112.11.4562.4562.

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Abstract Background: Bernard Soulier syndrome (BSS) is a platelet function disorder that results from partial to complete deficiency or dysfunction of the GP Ib-IX-V receptor. Specific treatment of bleeding episodes or prophylaxis for the prevention of bleeding during surgical procedures is platelet transfusion. Alloimmunization by HLA antigens and antibody formation to the GPIb-IX-V complex frequently occur and, thus limit future responses to platelet transfusions. Recent patient studies have suggested that rVIIa may be an effective therapy for treatment of bleeding in BSS. Case Reports: We report on our experience with rFVIIa in two patients with BSS and dental extraction. Patient 1 is a 21-year-old woman (extraction of 2 wisdom teeth). In 2000, after a first extraction of one wisdom tooth, which was covered by administration of DDAVP and platelet transfusion, a bleeding episode occurred, requiring resurgery. Patient 2 is a 14 year old boy (extraction of 4 wisdom teeth). rFVIIa was used as first line therapy. An initial dose of rFVIIa (100 μg/kg/bw) was administered 15 min prior to surgery, followed by three doses of 90 μg/kg/bw at 120 min intervals and three doses at 8 hour intervals postoperatively. In the first three days after surgery, 90μg/kg/bw rFVIIa were administered every 12 hours. Tranexamic acid (CyklokapronÒ 3 × 1 g/d) was started postoperatively and continued for 10 days. There were no postoperative bleeding episodes and no platelet transfusion was required. In conclusion, rFVIIa in combination with tranexamic acid appears to be an effective and safe therapeutic alternative for prophylaxis of bleeding episodes in dental extraction in patients with BSS.
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YOSHIDA, Kensuke, Yasumitsu KODAMA, Hirokazu ISOBE, Eiko YAMADA, Atsushi NISHIKAWA, and Ritsuo TAKAGI. "Survey of Antimicrobial Prophylaxis Agents and Surgical Site Infection Status Regarding Teeth Extraction in a Dental Outpatient Clinic." Japanese Journal of Infection Prevention and Control 33, no. 5 (2018): 207–12. http://dx.doi.org/10.4058/jsei.33.207.

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Marta, Sara Nader, José Eduardo de Oliveira Lima, Bernardo Gonzales Vono, Salete Moura Bonifácio da Silva, Maria Aparecida Andrade Moreira Machado, and Maria Ligia Gerdullo Pin. "Effect of professional cleaning and dental brushing with or without fluoridated dentifrice on enamel remineralization." Journal of Applied Oral Science 13, no. 3 (2005): 222–26. http://dx.doi.org/10.1590/s1678-77572005000300004.

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An in situ evaluation of the potential rehardening effect of fluoridated and non-fluoridated toothpastes with or without air polishing was conducted. Ten volunteers, using acrylic palatal appliances containing two bovine enamel blocks with artificial carious lesions, took part in this study. Four times a day, after the main meals and at night, the volunteers, in a habitual way, brushed their natural teeth with the dentifrice indicated to the experimental design and after that the appliances were put again into the mouth. They were divided into 4 different groups: G1 - control - non-fluoridated dentifrice; G2 - fluoridated dentifrice; G3 - non-fluoridated dentifrice, but having a previous prophylaxis using air polishing; G4 - fluoridated dentifrice and previous air polishing. The effects of treatments on enamel rehardening were evaluated in the blocks that were assessed by surface microhardness, and the percentage of surface microhardness change (%reh) was calculated in relation to the baseline values. The results showed that %reh was higher in the groups with fluoridated dentifrice, and professional prophylaxis did not have an additional effect in the groups of fluoridated dentifrices (p<0.05). The data suggested that, in the absence of fluoride, removal of dental plaque helped to increase the process of enamel rehardening.
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French, Sharon L., and James M. G. Anthony. "Surgical Removal of a Radicular Odontogenic Cyst in a Four Year Old Dalmatian Dog." Journal of Veterinary Dentistry 13, no. 4 (1996): 149–51. http://dx.doi.org/10.1177/089875649601300404.

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A cystic structure was identified radiographically in a four year old dog during routine dental prophylaxis. Surgical removal of the cyst lining was achieved by exposure of the site through extraction of the right first to third maxillary incisor teeth (101, 102, 103). The cyst lining was removed en-bloc. The cavity was curetted and filled with decalcified freeze-dried bone. Histological examination revealed a radicular cyst. The proposed etiology is blunt trauma to tooth 103, pulpal necrosis, apical granuloma and resulting cyst formation. Fourteen months following surgery, there was no recurrence of the cyst.
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O’Sullivan, Sean, José Carlos Almansa Ruiz, Arshad Toosy, and Gerhard Steenkamp. "Root canal treatments and crown lengthening in an adult jaguar (Panthera onca)." Veterinary Record Case Reports 7, no. 2 (2019): e000645. http://dx.doi.org/10.1136/vetreccr-2018-000645.

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Pathological dental conditions in zoo animals are frequently encountered, although under-reported in the veterinary literature. Teeth fractures are commonly encountered in carnivores and often require specialised endodontic intervention. This paper describes gingivectomy of a peripheral odontogenic fibroma of the left maxillary gingivae; crown lengthening of the left mandibular canine; and pulpectomies of complicated crown fractures of the left maxillary canine tooth (204), left mandibular canine tooth (304) and left third maxillary incisor (203) in an adult jaguar (Panthera onca). Follow-on dental examination at 18 months and postoperative radiographs at 24 months found no evidence of further dental pathology. Dental examination and prophylaxis are essential components of the examination procedure. There are limited opportunities to make routine clinical assessments in zoo animals. The availability of specialised materials, equipment and specialised veterinary assistance are limitations as relevant to zoological dentistry today as when described by Fowler in 1986.
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Ahmadi, Hanie, Alireza Ebrahimi, and Fatemeh Ahmadi. "Antibiotic Therapy in Dentistry." International Journal of Dentistry 2021 (January 28, 2021): 1–10. http://dx.doi.org/10.1155/2021/6667624.

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Dental caries, pulpal necrosis, trauma, and periodontal diseases can result in dental infections which could have severe consequences that affect both soft and hard tissues of the oral cavity. Dental infections commonly present with symptoms of pain, fever, and swelling. Surgical and endodontic treatments are the early management of infected teeth, followed by antibiotic therapy. Some alternative methods also exist for treating infection such as low-level laser therapy and photodynamic therapy. Antibiotics are generally used in dental procedures to treat odontogenic infections, nonodontogenic infections, local infection, focal infection, and prophylaxis. Antibiotic prophylaxis is prescribed for patients with immunosuppressed conditions, infective endocarditis, metabolic disorders, and patients with prosthetic joints. To reduce the complications of unnecessary antibiotic prescriptions especially bacterial resistance, comprehensive guidelines should be established. It has been noted that only about 12% of dentists adequately and correctly prescribe antibiotics, which shows the importance of comprehensive guidelines. Antibiotics prescription may result in some adverse effects such as hypersensitivity reactions and dermatological and allergic disorders. Furthermore, unnecessary prescription of antibiotics could result in several serious sequelae, for example, bacterial resistance, gastric and hematological problems, and diversion of bacterial microbiota. The present review attempts to summarize the indications of antibiotic therapy in dentistry and discuss the common types of antibiotics that are routinely used in dental practice based on pharmacologic classes. Moreover, types of antibiotics that are considered safe during pregnancy and childhood are also reviewed.
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Khamres, T. Y. "Assessment of periodontal disease using the CPITN index in rural population in Ninevah, Iraq." Eastern Mediterranean Health Journal 5, no. 3 (1999): 549–55. http://dx.doi.org/10.26719/1999.5.3.549.

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To estimate the prevalence of periodontal disease in a rural population and to assess the periodontal treatment needs, a sample of 1418 individuals aged between 7 years and 70 years, from three villages in Ninevah Governorate was examined using the community periodental index of treatment needs to assess their periodontal condition. Only 12.5% of the sample had healthy teeth and gums, and calculus was the most frequently observed periodontal condition. There is a need for dental prophylaxis and instruction in the use of oral hygiene procedures. There was no significant difference between males and females in periodontal health
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Miranda Filho, Aluísio Eustáquio de Freitas, Diego Henrique da Silva Soares, Petrus Leonardo Alves dos Santos, et al. "Dental treatment in child with congenital heart disease under general anesthesia: Clinical case report." Research, Society and Development 10, no. 6 (2021): e56510615907. http://dx.doi.org/10.33448/rsd-v10i6.15907.

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Congenital heart diseases consist of structural defects of the heart and represent serious malformations, which manifest in newborns, contributing significantly to perinatal mortality. The dental management of patients with this condition may require caution by professionals, owing to the possibility of bleeding and the risk of causing an infectious endocarditis due to the variety of microorganisms residing in the oral cavity. The present case report aimed to detail dental care under general anesthesia in a hospital for a child with congenital heart disease. Female patient, 4 years old, was diagnosed with atrial and interventricular communication and hemodynamic repercussion 21 days after birth. The patient received dental treatment according to the proposed plan, which included dental restorations, conservative pulp therapy and extraction of lower anterior teeth. Posteriorly, a removable partial prosthesis was made for the patient for the purpose of functional aesthetic rehabilitation. The use of general anesthesia may reduce the risk of infective endocarditis and allows the performance of several dental procedures with a single antibiotic prophylaxis, since the cardiac pediatric patient needs a correct planning of the procedures to be performed.
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Gonini, Cristiane de Andrade Janene, and Maria Celeste Morita. "Dental fluorosis in children attending basic health units." Journal of Applied Oral Science 12, no. 3 (2004): 189–94. http://dx.doi.org/10.1590/s1678-77572004000300005.

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OBJECTIVES: The purpose of this study was to determine the prevalence and severity of dental fluorosis among patients attending basic health units in Londrina. METHODS: Five basic health units of the urban area were randomly selected and 434 children attending these units, born between 1986 and 1989 (9 to 12 years of age), were examined. Diagnosis of dental fluorosis was performed by means of the Thylstrup and Fejerskov (TF) Index. Oral examinations were carried out by 5 previously trained dentists with the patients lying in the dental chair, under artificial light, preceded by prophylaxis, isolation with cotton rolls and air-drying of the teeth. Ten percent of the sample was reexamined and an almost perfect agreement on diagnostic criteria was obtained either on the intra-examiner or inter-examiner evaluation (K=1.00, p<0.0001). RESULTS: The observed prevalence of dental fluorosis was 91.0%, and 87.8% of the individuals were classified as TF grade 2 or less. CONCLUSIONS: Despite of the low severity, the high prevalence observed shows the need for regular screening of dental fluorosis in Londrina; establishment of procedures to prevent the overutilization of fluoride both by the professionals and the population; sanitary surveillance of fluoride levels in water supply and also in all sources of fluoride available; besides the need for further studies to understand the factors associated to dental fluorosis among children living in Londrina.
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Igic, Marija, Mirjana Apostolovic, Ljiljana Kostadinovic, Olivera Trickovic-Janjic, and Dusan Surdilovic. "The importance of health education in prevention of oral health in children." Medical review 61, no. 1-2 (2008): 65–70. http://dx.doi.org/10.2298/mpns0802065i.

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Health Education. The aim of education is to impart knowledge on the causes of disease and decay of the teeth and periodontium, on the ways and possibilities of disease prevention and adequate treatment; to point out to the necessity of proper nutrition, regular and proper oral hygiene, proper use of fluoride products as well as to the significance of regular check-ups with a dentist. Nutrition. Frequent intake of carbohydrates leads to a higher prevalence of caries. Taking into consideration that it is neither obtainable nor recommendable to completely eliminate glucoses from the nutrition components, it is necessary to advice parents and children to take glucose (if possible) only along with the regular meal when the saliva flow is increased. Oral Hygiene. In order to establish oral hygiene as an important prophylactic measure influencing successful protection of oral health of the whole population, it is necessary to inform as many people as possible about oral hygiene effectiveness and its necessity in preventing oral and dental diseases; to develop the habits of regular oral hygiene maintenance in the youngest children as well as to refer them to the use of most adequate paraphernalia and agents for performing the daily oral hygiene procedures. Fluoride prophylaxis. Undoubtedly, fluoride is currently the most efficient agent for the prevention of dental pathology. The anticaries efficacy of fluoride is a consequence of the cumulative effect of several different mechanisms. They can occur on the dental surface or directly influence the mineral phase in the enamel. Each dental hygiene preventive program must include the content about the use of fluoride as the basic prophylactic measure. It is recommended to be the sum of the combined effect of systemic (endogenic) and local (exogenic) application. Conclusion. Regarding high prevalence of caries in children, the issue of prophylaxis is of great significance and current interest. In that respect, health education should point out to the significance of proper nutrition, regular oral hygiene and fluoride prophylaxis, all aimed at preventing denial diseases. It is certain that parents must take an active part in these activities both as educators and controllers of the proposed measures. .
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Cherepyuk, Olena, Yuriy Oktysyuk, Alexandra Bazalytska, and Mykola Rozhko. "Correction of disordered oral immunity in children affected by dental caries with herbal immune modulator “Esberitox”." Pharmacia 67, no. 4 (2020): 347–50. http://dx.doi.org/10.3897/pharmacia.67.e35069.

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Dental caries is the most prevalent pathological condition in the child population of Ukraine. Despite the achievements of medical science, dental caries in children remains one of the most actual problems nowadays. Epidemiological investigations conducted in different regions of Ukraine demonstrate that 62% of children have decay and in many parts of the country the statistic is even higher up to 96.5% when the intensity of carious damage fluctuates between 3.2 to 7.2 teeth. This article reflects the results of the study regarding correction of disordered oral immunity indexes by immune modulator “Esberitox” in children affected by different caries activity. We have confirmed the high efficiency of the recommended scheme of caries prophylaxis that is proved by positive dynamic of oral immunological indexes observed 24 month after the beginning of the research. There was a certain rise of lysozyme by about 21.1% and s-IgA has increased by 28% in children from prophylactic groups in comparison with control groups.
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Mombelli, Andrea, Urs Brägger, and Niklaus P. Lang. "Microbiota Associated with Residual Clefts and Neighboring Teeth in Patients with Cleft Lip, Alveolus, and Palate." Cleft Palate-Craniofacial Journal 29, no. 5 (1992): 463–69. http://dx.doi.org/10.1597/1545-1569_1992_029_0463_mawrca_2.3.co_2.

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Twenty patients with residual clefts or pronounced soft tissue grooves, treated for uni- or bilateral cleft lip, alveolus, and palate were included in this study. Ten patients were recalled for dental prophylaxis at regular intervals, 10 patients were not. One microbiologic sample was obtained from the cleft area and two samples from a tooth adjacent to the cleft (sites adjacent and distant to the cleft). Between the recall and the nonrecall group there were notable differences in the presence of anaerobic Gram-negative organisms. Fusobacterium spp., Prevotella melaninogenica, and P, intermedia were more often found in nonrecall patients. While rarely seen in recall patients, spirochetes and motile rods were a common feature of nonrecall patients. The putative periodontal pathogens Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis were not detected in either group. The differences between the recall and the nonrecall groups were more pronounced when the respective samples from teeth were related to each other than when the samples obtained from the clefts were compared. The cleft flora was less complex irrespective of how good maintenance was and resembled the flora of teeth of well-maintained patients. Samples from clefts were never Wolinella positive, and harbored significantly less Capnocytophaga and Actinomyces viscosus than samples from dental sites.
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Guiñez Coelho, Marcial Andrés. "ICDAS and dmft/DMFT. Sensitivity and specificity, the importance of the index used: a systematic review." Journal of Dentistry & Public Health 11, no. 2 (2020): 176. http://dx.doi.org/10.17267/2596-3368dentistry.v11i2.3122.

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INTRODUCTION: Untreated dental caries is the most prevalent chronic disease in adults and untreated caries in deciduous teeth is the tenth most frequent chronic disease. Most of the studies do not present a representative population and there are no comparative studies between Decay - Missing - Filled in permanent teeth (dmft/DMFT) and International Caries Detection and Assessment System (ICDAS). We will seek to evaluate if there are differences in sensitivity and specificity in the diagnosis of caries using the ICDAS and dmft/DMFT index. OBJECTIVES: The objective of the investigation is to evaluate if there are differences in the sensitivity and specificity in the detection of caries using the ICDAS and dmft/DMFT indexes. METHODS AND MATERIALS: A qualitative systematic review was performed, searching the dmft/DMFT caries index and ICDAS in the Medline, ClinicalKey and SciELO databases, finding 3,581 of which 21 were read in full and 14 met the inclusion and exclusion criteria. RESULTS: The sensitivity and specificity are higher with ICDAS than with the dmft/DMFT index and provides up to 43% more information when detecting noncavitated lesions, but requires more time and resources due to the use of light, compressed air and pre-examination prophylaxis. Previous training, knowledge and experience in ICDAS are fundamental for the best result, studies showed that the more experience the sensitivity and specificity increased, unlike the dmft/DMFT index, although ICDAS was easy to understand by inexperienced professionals. CONCLUSION: More comparative studies between both indexes should be carried out and include ICDAS in children due to their ability to detect non-cavitated lesions which are the most prevalent in temporary teeth.
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Poornachitra, Poornachitra, Jayanth Kumar Vadivel, Geetha R. V, and Subha Manoharan. "Comparison of Antimicrobial Potency Assay of Common Antibiotic Prophylaxis Drugs Recommended in Dentistry for Preventing Infective Endocarditis - An Invitro Study from Chennai, India." Journal of Evolution of Medical and Dental Sciences 10, no. 31 (2021): 2384–89. http://dx.doi.org/10.14260/jemds/2021/489.

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BACKGROUND Infective endocarditis [IE] prophylaxis is recommended for all dental procedures that involve manipulation of gingival tissue or the periapical region of teeth or perforation of the oral mucosa. The study intended to compare the antimicrobial potency of amoxicillin, cephalexin, and clindamycin against Streptococcus mutans, the common causative organism of dental infections. The objective was to assess the potency of recommended choice of antibiotics and its efficacy among each other in infective endocarditis prophylaxis during dental procedures. METHODS Saliva samples [N = 20] were collected from patients susceptible for IE and Streptococcus mutans was cultured in Infusion Agar. The principle used in this study was based on the Kirby - Bauer disc diffusion Antimicrobial Susceptibility Test [AST] Method and minimum inhibitory concentration [MIC]. In this method, the three HiMedia antibiotic discs of amoxicillin, cephalexin and clindamycin were loaded and assessed for measurable “zone of inhibition” against mutans. RESULTS One-way ANOVA was used to compare the means of zone of inhibition of each disc. The test was statistically significant with F value of 4.093 at P value 0.038. Post hoc analysis was conducted using Tukey’s HSD test as one-way ANOVA was statistically significant. The mean difference of 13.16 mm between amoxicillin and cephalexin was found to be statistically significant at P value 0.041 with lower and upper bound at 0.527 and 25.806 respectively. The mean difference of 2.65 mm between amoxicillin and clindamycin and - 10.50 mm between cephalexin and clindamycin was not found to be statistically significant. CONCLUSIONS Amoxicillin showed to be more potent among the antibiotics chosen for this study. Clindamycin showed to be a better alternative to cephalexin and could be the first choice in case of patients allergic to penicillin group of drugs. KEY WORDS Antibiotic Prophylaxis, Infective Endocarditis, Antimicrobial Potency, Minimum Inhibitory Concentration [MIC], Antimicrobial Susceptibility Test [AST], Kirby Bauer Disk Diffusion Method
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Siqueira, Viviane Da Silva, Aury Elianny Sanchez Castillo, Jose Francisco Mateo-Castillo, Lidiane De Castro Pinto, Daniela Garib, and Cláudia Ramos Pinheiro. "Dental hypersensitivity in individuals with cleft lip and palate: Origin and therapies." Journal of Dental Research, Dental Clinics, Dental Prospects 15, no. 1 (2021): 42–46. http://dx.doi.org/10.34172/joddd.2021.008.

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Background. Dental hypersensitivity is due to the exposure of the dentin layer after wear of enamel or cementum, exposing the dentinal tubules and the nerve endings of odontoblasts within these tubules. The present study aimed to assess the factors related to dental hypersensitivity in individuals with cleft lip and palate and the most common therapy received. Methods. The medical records of 536 patients with cleft lip and/or palate (281 males, 255 females) with a mean age of 18 were analyzed in a single center. The inclusion criterion was patients reporting dental hypersensitivity from May 2015 to October 2019. The origin of dental hypersensitivity was evaluated considering orthodontic movement, periodontal diseases, and reversible and irreversible pulpitis. The therapy indicated by the dental professionals for dental hypersensitivity were recorded. Descriptive statistics were performed. Results. Of 61 teeth with dental hypersensitivity, 10 were attributed to orthodontic movement, 21 to periodontal problems, 27 to reversible pulpitis, and three to irreversible pulpitis. The most used therapies were the application of fluoride varnish and prophylaxis, dentifrice indication for dental sensitivity, free gingival grafts, pulpectomy, desensitizing agent application, conservative endodontic treatment (direct pulp protection), and restoration of non-carious cervical lesions. Conclusion. Reversible pulpitis was the most prevalent etiologic factor of dental hypersensitivity in individuals with cleft lip and palate. Dentifrices for dental sensitivity and fluoride varnish application were frequently recommended.
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Troxel, Mark. "Iatrogenic Traumatic Brain Injury During Tooth Extraction." Journal of the American Animal Hospital Association 51, no. 2 (2015): 114–18. http://dx.doi.org/10.5326/jaaha-ms-6094.

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An 8 yr old spayed female Yorkshire terrier was referred for evaluation of progressive neurological signs after a routine dental prophylaxis with tooth extractions. The patient was circling to the left and blind in the right eye with right hemiparesis. Neurolocalization was to the left forebrain. MRI revealed a linear tract extending from the caudal oropharynx, through the left retrobulbar space and frontal lobe, into the left parietal lobe. A small skull fracture was identified in the frontal bone through which the linear tract passed. Those findings were consistent with iatrogenic trauma from slippage of a dental elevator during extraction of tooth 210. The dog was treated empirically with clindamycin. The patient regained most of its normal neurological function within the first 4 mo after the initial injury. Although still not normal, the dog has a good quality of life. Traumatic brain injury is a rarely reported complication of extraction. Care must be taken while performing dental cleaning and tooth extraction, especially of the maxillary premolar and molar teeth to avoid iatrogenic damage to surrounding structures.
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Souza, Danielle Ferreira Sobral de, Josué Junior Araújo Pierote, Flávio Henrique Baggio Aguiar, Luís Alexandre Maffei Sartini Paulillo, and Débora Alves Nunes Leite Lima. "Resolution of a fluorosis case through the association of minimally invasive techniques." Brazilian Journal of Oral Sciences 18 (November 18, 2019): e191663. http://dx.doi.org/10.20396/bjos.v18i0.8657330.

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Color changes may interfere with smile balance and they represent a clinical challenge to dentists. Dental fluorosis originates from intrinsic factors and it is a disorder of enamel formation during the phase of teeth development, resulting in the change of enamel color. This clinical case report aimed to present the resolution of a case of dental fluorosis through the association of minimally invasive techniques, namely microabrasion and tooth bleaching. A 27-year-old male patient sought the dental clinic of the School of Dentistry of Piracicaba (FOP - UNICAMP, Brazil) presenting striped and symmetrical white stains and generalized chromogenic biofilm. After anamnesis and clinical examination, the patient was diagnosed with fluorosis stains. Initially, adequacy of the oral environment was performed with prophylaxis and supragingival scraping. Then, the enamel microabrasion technique was performed with 6% hydrochloric acid associated with silicon carbide (Whiteness RM - FGM) and supervised at-home bleaching was performed with 16% carbamide peroxide (Whiteness Simple 16% - FGM). In conclusion, the treatment performed reestablished the aesthetics and harmony of smile color with minimally invasive procedures without causing tooth sensitivity.
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Folwaczny, Matthias, Saskia Wilberg, Caspar Bumm, et al. "Oral Health in Adults with Congenital Heart Disease." Journal of Clinical Medicine 8, no. 8 (2019): 1255. http://dx.doi.org/10.3390/jcm8081255.

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Oral bacteria and odontogenic oral infections are responsible for a high portion of cases with infective endocarditis. Hence, oral health in patients with congenital heart disease (CHD) gains particular importance. This case-control study compared the oral health status in 112 adults with CHD and 168 healthy control subjects. In addition, the patient group was stratified according to the complexity of the heart defect and the recommendation for antibiotic prophylaxis during invasive dental procedures. Considering caries experience, a significantly lower mean DMFT (decayed missing filled teeth) score (7.91 ± 6.63 vs. 13.6 ± 8.15; p < 0.0001) was found in patients with CHD compared to healthy controls. Healthy controls had a higher average number of decayed teeth (0.33 ± 0.76 vs. 1.76 ± 2.61; p < 0.0001). In female subjects a significant lower relative amount of teeth with apical periodontitis was found among CHD patients (3.4% ± 0.9%) as compared to healthy controls (5.6% ± 1.9%) (p = 0.053). Regarding periodontal health, patients with CHD had lower rate of sulcus bleeding (0.32 ± 0.65 vs. 0.71 ± 0.60; p < 0.0001) and less alveolar bone loss than heart healthy individuals (% root length: multi rooted teeth: 8.97 ± 10.64 vs. 23.22 ± 20.70; p < 0.0001; single rooted teeth: 5.59 ± 6.25 vs. 17.30 ± 17.17; p = 0.003). On the contrary, CHD patients presented with higher amount of plaque in comparison to healthy controls (Quigley & Hein index: 2.22 ± 0.67 vs. 1.25 ± 0.72; p < 0.0001). Based on the current results, it can be concluded that adults with CHD have better oral health than heart healthy individuals.
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Sathvika K, Anjaneyulu K, and Leelavathi L. "Comparison of incidence of dental caries in the mandibular first molar in teenagers versus adults." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (2020): 639–44. http://dx.doi.org/10.26452/ijrps.v11ispl3.2995.

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The mandibular first molars are one of the first permanent teeth to erupt; thus, it remains the longest in terms of exposure to cariogenic pathogens. Also, its anatomical location and structure make it a prime location for dental caries (DC) but hard to access for cleaning. Thus, we aim to compare its incidence in adults and teenagers because the identification of the most susceptible age for tooth decay is key in prevention and prophylaxis against the same. A retrospective cross-sectional study was conducted by reviewing and analysing the data of 86,000 patient records from June 2019 to April 2020. Patients with treated mandibular first molars were selected from the age group of 13 and above. A Microsoft Excel 2016 data spreadsheet was used to collect data and was later exported to the Statistical Package for the Social Sciences for Windows (Version 20.0, SPSS). The number of males with DC in their mandibular first molar (59%) was higher than that of the females (41%). The highest number of cases were reported to prevail in the 'Young Adults' group, with 56.7%, followed by the 'Middle Adults' with 26%. This shows that adults have a higher incidence of DC in their mandibular first molars than teenagers. Also, there was a clear incidence of 46 having a higher incidence than caries in 36. (52.5% > 47.5%). There is an association between age and incidence of dental DC as proved by our Chi-Square Test, where we obtained a 'p' value of p<0.05, making it statistically significant. Once lost, our teeth cannot be naturally replaced, making prevention imperative. Thus, identifying the age in which we are most prone to decay is a great leap forward. But since the study does present with limitations, further research needs to be done to confirm the same.
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Cervino, Gabriele, Marco Cicciù, Antonio Biondi, et al. "Antibiotic Prophylaxis on Third Molar Extraction: Systematic Review of Recent Data." Antibiotics 8, no. 2 (2019): 53. http://dx.doi.org/10.3390/antibiotics8020053.

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The aim of this paper was to highlight the most widely antibiotic protocols applied to the dental field, especially in the surgical treatment of impacted wisdom teeth. Once these protocols were screened, all the possible advantages or disadvantages for each drug and each posology were recorded in this review. In recent years, the need to use these protocols has been debated in the literature. The data obtained by this review underlined how antibiotic protocols applied to oral surgery treatments only included surgeries performed on patients who did not present other systemic pathologies. The first literature review obtained 140 results, and then after the application of the inclusion criteria, 12 papers were selected. The results showed that the most commonly used protocol involved the use of penicillin and clavulanate, obtaining safe clinical and prophylactic results in the management of infections. This widely used protocol seems to guarantee high predictability and safety. The presented review highlights the current possibility of antibiotic resistance affecting patients due to drug misuse. Further clinical studies are required to state specific guidelines; however, oral surgeons involved in third molar surgery should evaluate the local and general health conditions of the patients before suggesting any drug measures for patients.
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Fernández, E., C. Bersezio, J. Bottner, et al. "Longevity, Esthetic Perception, and Psychosocial Impact of Teeth Bleaching by Low (6%) Hydrogen Peroxide Concentration for In-office Treatment: A Randomized Clinical Trial." Operative Dentistry 42, no. 1 (2017): 41–52. http://dx.doi.org/10.2341/15-335-c.

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SUMMARY Objective: The aim was to evaluate the color longevity after nine months of in-office bleaching with gel (6% hydrogen peroxide), to compare this to a control concentration of 35% in a split-mouth study model, and to assess the dental confidence and psychosocial impact on patients. Methods and Materials: Twenty-seven patients were assessed at the nine-month recall. The bleaching procedure with 6% or 35% hydrogen peroxide gel was performed randomly in the upper hemi-arch of each patient. The color was measured at baseline and at one week, one month, and nine months after the procedure, using the Vita Easyshade spectrophotometer, the Vita classical shade guide organized by value, and Vita Bleach Guide 3DMaster. Moreover, two surveys, OHIP-Esthetics and PIDAQ, were used to assess the esthetic self-perception and psychosocial impact of the bleaching procedure. During the nine-month recall, the color was assessed before and after dental prophylaxis. Results: Twenty-seven patients participated in the nine-month recall. There was a significant difference in ΔE between the two groups at all times assessed (p<0.011). The ΔL, Δa, and Δb showed a difference between the two groups at all times assessed (p<0.038), except for ΔL from the baseline vs nine-month after prophylaxis value (p>0.20). There was no significant difference in ΔSGU at all times (p>0.05). There was a significant difference in OHIP-Esthetics and PIDAQ sums compared with baseline scores (p<0.03). Conclusion: The two compounds remained effective at nine months, with a slight rebound of color, and maintained their objective color difference but not the subjective color difference. Patients were satisfied with the bleaching procedure, and this had a positive impact on esthetic perception and a positive psychosocial impact at the nine-month recall.
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Togoo, Rafi Ahmed, Mohammed A. Al-Rafee, Reena Kandyala, Master Luqam, and Mohammed A. Al-Bulowey. "Dentists’ Opinion and Knowledge about Preventive Dental Care in Saudi Arabia: A Nationwide Cross-sectional Study." Journal of Contemporary Dental Practice 13, no. 3 (2012): 261–65. http://dx.doi.org/10.5005/jp-journals-10024-1134.

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ABSTRACT Aim The aim of this study was to determine the dentists’ opinions on causes for high prevalence of dental caries in the country and to assess their level of knowledge about preventive dental care. Materials and methods A questionnaire based national crosssectional survey among 500 dentists was conducted under the auspices of Directorate of Dentistry, Ministry of Health. The data was analyzed using SPSS software version 11.0 and descriptive statistics were obtained. Results The response rate was 87.8% (n = 439). 83% of dentists identified poor oral hygiene as the major reason for high prevalence of caries, only 39% of patients reportedly brushed teeth at least once a day, oral prophylaxis (83%) is the most common preventive practice followed, social factors (62.5%) are the most challenging barriers in preventive dental programs, 71.3% always give chair side dental health education, school based programs (66.6%) are most effective tools for dental health education. Conclusion Majority of dentists in Saudi Arabia are adequately informed and motivated toward preventive dental care but they are in need of further support from policy makers to enhance preventive dental programs in the Kingdom. Clinical significance Oral hygiene should be improved in the country by reaching out to the entire community through extensive and continued education programs. How to cite this article Togoo RA, Al-Rafee MA, Kandyala R, Luqam M, Al-Bulowey MA. Dentists’ Opinion and Knowledge about Preventive Dental Care in Saudi Arabia: A Nationwide Cross-sectional Study. J Contemp Dent Pract 2012;13(3): 261-265.
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41

Österberg, Marie, Anders Holmlund, Bo Sunzel, Sofia Tranæus, Svante Twetman, and Bodil Lund. "KNOWLEDGE GAPS IN ORAL AND MAXILLOFACIAL SURGERY: A SYSTEMATIC MAPPING." International Journal of Technology Assessment in Health Care 33, no. 1 (2017): 93–102. http://dx.doi.org/10.1017/s026646231700023x.

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Objectives: The aim of this study was to evaluate available knowledge and identify knowledge gaps within the field of oral and maxillofacial surgery, by systematically collecting and evaluating systematic reviews. Twelve specific domains were selected: surgical removal of teeth, antibiotic and corticosteroid prophylaxis, orofacial infections, dental and facial trauma, orthognathic surgery, reconstructive surgery, benign tumors, cysts, premalignant lesions, oral complications of treatment of malignant tumors, hyperbaric oxygen therapy, temporomandibular joint surgery, cost effectiveness of different surgical treatments, and ethics.Methods: The literature search, covering four databases, was conducted during September 2014: PubMed, The Cochrane library, Centre for Reviews and Dissemination and EBSCO dentistry and oral science source. Retrieved systematic reviews were quality assessed by AMSTAR.Results: In all, 1,778 abstracts were identified, of which 200 met the inclusion criteria. Forty-five systematic reviews were assessed as of high to moderate quality. The results disclosed some existing evidence in a few domains, such as surgical removal of teeth and implant survival after sinus lifts. However, in all domains, the search revealed a large number of knowledge gaps. Also of concern was the lack of data regarding health economics and ethics.Conclusions: In conclusion, there is a need for well-conducted clinical research in the fields of oral and maxillofacial surgery.
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42

Gerhardt, Andrea, Rudiger E. Scharf, and Rainer B. Zotz. "The Use of Recombinant Factor VIIa (NovoSeven®) in a Patient with Bernard Soulier Syndrome and Dental Extraction." Blood 108, no. 11 (2006): 3961. http://dx.doi.org/10.1182/blood.v108.11.3961.3961.

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Abstract Background: Bernard Soulier syndrome is a rare autosomal recessive platelet function disorder that impairs platelet adhesion to von Willebrand factor, especially at high shear flow. The disorder results from partial to complete deficiency or dysfunction of the GP Ib-IX-V receptor. Bernard Soulier syndrome typically results in prolonged bleeding time, thrombocytopenia, and giant platelets. The main clinical symptoms, evident from early childhood, include frequent episodes of epistaxis and hemorrhage associated with mucocutaneous bleeding or trauma. Specific treatment of bleeding episodes or prophylaxis for the prevention of bleeding during surgical procedures are platelet transfusions. This treatment option is not devoid of complications. Alloimmunization by HLA antigens and antibody formation to the GPIb-IX-V complex frequently occur and, thus limit future responses to platelet transfusions. Recent patient studies have suggested that recombinant factor VIIa (rVIIa, NovoSeven®) may be an effective therapy for treatment of bleeding in patients with congenital platelet function defects and other acquired platelet disorders, including thrombocytopenia. Case Reports: We report on our experience with rFVIIa in a 21-year-old woman with Bernard Soulier syndrome and dental extraction (2 wisdom teeth). In 2000, after a first extraction of one wisdom tooth, that was covered by administration of DDAVP and platelet transfusion, a bleeding episode occurred, requiring resurgery. This time rFVIIa was used as first line therapy. An initial dose of rFVIIa (100 μg/kg/bw) was administered 15 min. prior to surgery, followed by two doses of 90 μg/kg/bw at 120 min intervals postoperatively. In the first three days after surgery, 90μg/kg/bw rFVIIa were administered every 12 hrs. Tranexamic acid (Cyklokapron® 3 x 1 g/d) was started postoperatively and continued for 10 days. There were no postoperative bleeding episodes and no platelet transfusion was required. In conclusion, rFVIIa in combination with tranexamic acid appears to be an effective and safe therapeutic alternative for prophylaxis of bleeding episodes in dental extraction in patients with Bernard Soulier syndrome.
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43

Schaeken, M. J. M., and P. De Haan. "Effects of Sustained-release Chlorhexidine Acetate on the Human Dental Plaque Flora." Journal of Dental Research 68, no. 2 (1989): 119–23. http://dx.doi.org/10.1177/00220345890680020401.

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The aim of this study was to determine the effect on the human dental plaque flora of a varnish containing chlorhexidine diacetate. The in vitro release of chlorhexidine acetate from the varnish preparation was relatively fast on the first day, followed by a substantial decline in the subsequent three days. In a clinical experiment, 26 volunteers were randomly distributed over four experimental groups. After a dental prophylaxis, the subjects were treated with a single application of a placebo varnish (group I), a fluoride varnish (group II), a chlorhexidine varnish (group III), or a fluoride-plus-chlorhexidine varnish (group IV). Saliva and pooled plaque samples from approximal surfaces were taken before (baseline) and one, two, three, four, and six weeks after the treatments. No suppression was found of total cultivable flora or S. sanguis after the experimental treatments. Application of the fluoride varnish did not suppress the A. viscosus/naeslundii or S. mutans levels in the dental plaque. Chlorhexidine suppressed A. viscosus/naeslundii until two weeks after the treatment. S. mutans was significantly suppressed until four weeks after a single chlorhexidine application. While in some subjects S. mutans was effectively suppressed over the whole experimental period, in others S. mutans recovered quickly. In five subjects in whom S. mutans recovered quickly, the dentition was treated twice with chlorhexidine varnish, with an interval of one week between the treatments. After two chlorhexidine treatments, S. mutans in saliva and on the teeth was suppressed more strongly than after a single treatment. However, the second chlorhexidine treatment could not prevent the return of S. mutans in the approximal areas to its original level.
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44

Ivanovic, Branislava, Snezana Matic, Milorad Pavlovic, Marijana Tadic, and Dragan Simic. "Are new recommendations on the prevention of infective endocarditis applicable in our environment?" Srpski arhiv za celokupno lekarstvo 138, no. 11-12 (2010): 714–20. http://dx.doi.org/10.2298/sarh1012714i.

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Introduction. Over half a century ago the process of prevention of infective endocarditis in patients with predisposed cardiac diseases was started. The application of prevention has been based on the fact that infective endocarditis is preceded by bacteraemia, which can be caused by some invasive diagnostic and therapeutic procedures, and whose development can be prevented by applying antibiotics before an intervention. According to the latest guidelines of the European Society of Cardiology published this year, prevention is recommended only in high risk patients with previous infective endocarditis, prosthetic valves, cyanotic congenital heart diseases without surgical repair or with residual defects, palliative shunts or conduits, congenital heart diseases with complete repair with prosthetic material up to six months after the procedure (surgery or percutaneous intervention), and when the residual defect persists at the site of implantation of a prosthetic material. In addition, antibiotic prophylaxis is limited to dental procedures with the manipulation of gingival or periapical region of the teeth or perforation of the oral mucosa. Objective. The aim of this testing was to confirm whether these novelties in recommendations were applicable in our environment. Methods. Fifty-seven patients (44 men and 13 women) with infective endocarditis were included in the testing. Infective endocarditis was diagnosed in 68% of patients based on two major criteria and in 32% based on one major and three minor criteria. Results. In 54.4% of patients the entry site of infection could be determined. Twenty-one percent of patients developed infection after a dental intervention, 17.5% of patients the infection occurred after a skin/soft tissue lesion, whereas urinary infection preceded infective endocarditis in 14% of patients and bowel diverticulosis was a possible cause in of 1.75% of patients. In all cases with infective endocarditis preceded by the dental intervention, antibiotic prophylaxis was not applied due to absent data of heart disease or negligence. Conclusion. In our country a high incidence of infective endocarditis following dental procedures has been observed. One of possible reasons is poor oral hygiene. Its improvement and a regular dental control, as well as the individual risk assessment of intervention and conditions under which the intervention is performed could determine risk reduction for the development of infective endocarditis.
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Loyola-Rodriguez, Juan Pablo, Ana Alicia Aguilera-Morelos, Miguel Angel Santos-Diaz, et al. "Oral rehabilitation under dental general anesthesia, conscious sedation, and conventional techniques in patients affected by cerebral palsy." Journal of Clinical Pediatric Dentistry 28, no. 4 (2004): 279–84. http://dx.doi.org/10.17796/jcpd.28.4.e103u071237388h8.

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The purpose of this report is to find the use of different alternatives for dental treatment, from general anesthesia to conventional techniques, in patients affected by cerebral palsy (CP) in a dental school setting.The sample was divided into two groups: (1) children, and (2) adolescents and young adults; 38 patients (20 female and 18 male) with diagnostic of CP were included. Risks and benefits of conscious sedation and general anesthesia were written into a consent form and these were discussed with parents or guardians of each affected patient.The mean age was 7.14 ± 2.2 years for children's group and 18.5 ± 3.06 years for adolescent and young adult group.Most children (77.3%) were classified as ASA II with a level of behavior I-II according to Frankl's scale and these patients were treated under general anesthesia (GA). For patients that were classified as of positive behavior with little necessity of dental procedures, independent of the medically compromised level, dental treatment was done with conventional techniques or with conscious sedation. Dental frequency procedures were as follows: composites, dental prophylaxis, and dental extractions in children; in adolescents and adults, important to point out is that in anterior teeth and molars endodontic treatment, and surgical procedures increased in frequency. The mixture sevoflurane-propofol worked well during pre-, peri-, and post-operative procedures. During the discharge process, most patients needed a recovery of 20-40 minutes, after which they were awake and oriented, breathing comfortably with stable vital signs. It was concluded that GA with sevoflurane-propofol and conscious sedation are an excellent tool to provide dental treatment in CP patients in a dental school setting without most of the major postoperative complications, such as nausea and vomiting.
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Maharani, Diah Ayu, Alia Ramadhani, Melissa Adiatman, et al. "EFFICACY OF MOUTH RINSE FORMULATION BASED ON CETYLPYRIDINIUM CHLORIDE 0.1% IN THE CONTROL OF DENTAL CALCULUS BUILDUP." International Journal of Applied Pharmaceutics 9 (October 30, 2017): 176. http://dx.doi.org/10.22159/ijap.2017.v9s1.84_91.

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Objective: This study aimed at comparing the antiplaque, anticalculus, and antigingivitis potentials of a mouth rinse containing essential oil, alcohol,zinc, and fluoride with a mouth rinse containing cetylpyridinium chloride (CPC) 0.1% over 1-, 2-, and 3-month periods.Methods: This study was a double-blind, parallel randomized clinical trial with a 3-day run-in phase. Respondents were asked to gargle twice dailywith 15 ml of mouth rinse for 30 seconds after brushing teeth. Respondents were 80 females with a mean age of 21 years, and a single dental examinerwas employed throughout the study to decrease the variance. Prophylaxis was performed for all respondents before the intervention. Three mouthrinses were tested: Group 1 with the mouth rinse containing CPC 0.1%, Group 2 as the negative control, and Group 3 as the positive control with amouth rinse containing alcohol. Evaluations were conducted by plaque index, gingival index, calculus index, and CariScreen examinations.Results: The clinical trial showed that the mouth rinse with alcohol and the mouth rinse containing CPC 0.1% were effective in inhibiting bacterialbuildup (antiplaque) and have anticalculus properties, but with no statistically significant antigingivitis effect.Conclusion: It was found that the mouth rinse containing alcohol has similar effectiveness with CPC 0.1% mouth rinse, but side effects, such as aburning sensation, were reported in the alcohol-containing mouth rinse.
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47

Kokoceva Ivanovska, Olga. "Local etiological factors for the appearance of early childhood caries." Archives of Public Health 12, no. 2 (2020): 46–55. http://dx.doi.org/10.3889/aph.2020.5218.

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In the early childhood, at the age of 1 to 1.5 year, immediately after teeth eruption, a special form of caries which spreads only over the primary teeth, often appears. The aim of this study was to determine local factors that affect the occurrence of this dental disease in early childhood.Materials and methods: Our examinees were children 1.5-3.5 years old, where during the standard check-ups we diagnosed starting phases of circular caries: initial lesion (white spot) and superficial form. The mothers of children with diagnosed circular caries were provided with a pre-prepared questionnaire containing data on: the length of the breastfeeding period, the infant's feeding with a bottle and the most commonly consumed contents, oral hygiene habits after feeding the infant, and tooth brushing. Results: Only 30% of mothers breastfed (children) by the 6-th month and 40% by the third month and shorter. About 15% of mothers received fluoride prophylaxis during pregnancy and lactation. The largest percentage of respondents (48%) were fed with a baby bottle, over a prolonged period of time, up to three or more years, mostly with industrial juices (48%). They were mostly consumed at night (40%). Oral-hygiene measures after bottle feeding were observedonly in 16%. The daily frequency of tooth brushing in young children is at most once a day (32%). Conclusion: The analysis of the results showed that circular caries is more common in children who have been breastfed for shorter period and who used the bottle in their daily diet. The most commonly consumed are industrial juices, which are considered "cariogenic drinks" because they are potentially dangerous to primary teeth, especially when consumed at night (pH of saliva drops to 0).
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Vozniy, O. V., T. Ye Shumna, and Ye S. Lepetchenko. "THE EPIDEMIOLOGICAL ASPECTS OF CARIES SPREADING AND THE PECULIARITY OF DEVELOPMENT OF CARIOGENIC SITUATION IN THE CHILDREN WITH BRONCHIAL ASTHMA." Ukrainian Dental Almanac, no. 2 (June 25, 2018): 41–44. http://dx.doi.org/10.31718/2409-0255.2.2018.10.

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Tooth decay is the most important early age children problem of the health of the oral cavity. It is medical and social problem of many developed countries and countries with transitional economy.
 According to WHO, in some countries the frequency and the intensity of dental caries decrease, however the same indexes in Ukraine increase rapidly and systematically.
 The interconnection of dental diseases and general somatic pathology is known well and it occupies one of the leading places amongst the main reasons of dental caries. The occurrence of bronchial asthma among child population varies from 1% till 18%. Therefore, children with the diseases of respiration organs have higher marks of caries lesions than healthy children.
 The aim of the work is to carry out the analysis of the specialized scientific literature for the data generalization on the modern looks on the prophylaxis and treatment of dental caries, its complications and the condition of dental health in children with bronchial asthma.
 Materials and methods. We have studied and analyzed the scientific literature available in the last years, which is devoted to the peculiarity of prevalence of dental diseases, prophylaxis and treatment of tooth decay, its complications and the condition of dental health in children with bronchial asthma.
 There are different indexes of caries prevalence and intensity in Ukraine according to our research. Thus, in the western regions the prevalence comes up to 93-100% and intensity 3,4-6,5, whereas in the central and south-east regions the same marks are up to 73-93% and 2,0-4,3.
 There is a huge influence on the caries prevalence by genetic tendency, attendant somatic pathology, social and hygienic factors.
 It is known that patients with bronchial asthma use inhalation glucocorticosteroids as basic treatment. This fact places them into the group of higher risk of caries development. But the influence of these drugs on the progress of tooth decay and saliva secretion is not studied well. Scientists confirm that the use of inhalation glucocorticosteroids can change chemical and immune compound of oral liquid (decrease saliva secretion speed, pH, number of calcium, phosphor, lysozyme and the raise of saliva viscosity). All these changes along with decrease of Ig A and ptyalin amount makes these children defenseless to caries and assists in development of cariogenic situation in the oral cavity. Moreover, children with allergic pathology have changes of immune reactivity and dysfunction of albumen and mineral exchange. At the same time the lesion of hard tissues of teeth in children with hypoxia which is determined as inborn and heritable diseases most often appear as the systemic hypoplasia in combination with plural caries. Caries prevalence in children with bronchial asthma is about 88-89% according to the latest news.
 We need also to draw attention to the changes of the osseous tissue. It depends not only on burden and duration of bronchial asthma, but also on the peculiarity of progression of caries process. These children have low mineral density and modified indexes of mineral and bone exchanges.
 All this facts confirm the systemic character of the bone lesion in these patients. Therefore, the rate of alterations grows up proportional to intensity of tooth decay.
 Conclusions. Thus, the analysis of the data, as well as our own research, have demonstrated the necessity of study of described problem and elaboration of specific prophylaxis program of dental caries and its complications in children with bronchial asthma more deeply.
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49

Voznyi, O. V., T. Ye Shumna, and Ye S. Lepetchenko. "THE EPIDEMIOLOGICAL ASPECTS OF CARIES PREVALENCE AND THE PECULIARITY OF DEVELOPMENT OF CARIOGENIC SITUATION IN THE CHILDREN WITH BRONCHIAL ASTHMA." Ukrainian Dental Almanac, no. 3 (September 4, 2018): 42–46. http://dx.doi.org/10.31718/2409-0255.3.2018.07.

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Tooth decay is the most important early age children problem of the health of oral cavity. It is medical and social problem of many developed countries and countries with transitional economy.
 According to WHO, in some countries the frequency and the intensity of dental caries decrease, however the same indexes in Ukraine increase rapidly and systematically.
 The interconnection of dental diseases and general somatic pathology is well known and it occupies one of the leading places among the main reasons of dental caries. The prevalence of bronchial asthma among child population varies from 1% till 18%. Herewith, children with the diseases of respiration organs have higher marks of caries defeat than healthy children.
 The aim of the work is to carry out the analysis of the specialized scientific literature for the data generalization about modern looks to the prophylaxis and treatment of dental caries, its complications and the condition of dental health in children with bronchial asthma.
 Materials and methods. We have analyzed and studied the available scientific literature in the last years, which is devoted to the peculiarity of prevalence of dental diseases, prophylaxis and treatment of tooth decay, its complications and the condition of dental health in children with bronchial asthma.
 According to our research, there are different indexes of caries prevalence and intensity in Ukraine. Thus, in the western regions prevalence come up to 93-100% and intensity 3,4-6,5, whereas in the central and south-east regions the same marks come up to 73-93% and 2,0-4,3.
 There is a huge influence on the caries prevalence by genetic tendency, attendant somatic pathology, social and hygienic factors.
 It is generally known that patients with bronchial asthma use inhalation glucocorticosteroids as basic treatment. This fact places them into the group of higher risk of caries development. But the influence of these drugs on the progress of tooth decay and saliva secretion is not well studied. Scientists confirm that the use of inhalation glucocorticosteroids can change chemical and immune compound of oral liquid (the descent of saliva secretion speed, pH, number of calcium, phosphor, lysozyme and the upsurge of saliva viscosity). All these changes along with diminution of Ig A and ptyalin amount makes these children more defenseless to caries and assist in development of cariogenic situation in the oral cavity. Moreover, children with allergic pathology have changes of immune reactivity and dysfunction of albumen and mineral conversion. At the same time the defeat of hard tissues of teeth in children with hypoxia which is determined by inborn and heritable diseases most often appear as the systemic hypoplasia in combination with plural caries. Caries prevalence in children with bronchial asthma is about 88-89% according to the latest news.
 We need also to draw attention to the changes of the osseous tissues. They depend not only on burden and duration of bronchial asthma, but on the peculiarity of progression of caries process. These children have low mineral density and modified indexes of mineral and bone exchange.
 All this facts confirm about the systemic character of the bone defeat in this patients. Herewith, the stage of alteration grows up proportional to intensity of tooth decay.
 Conclusions. Thus, the analysis of literary data, as well as own research, have demonstrated the necessity of in-depth study of described problem and elaboration of specific prophylaxis program of dental caries and its complications in children with bronchial asthma.
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50

Taira, Even A., Talita M. S. Ventura, Luiza P. S. Cassiano, et al. "Changes in the Proteomic Profile of Acquired Enamel Pellicles as a Function of Their Time of Formation and Hydrochloric Acid Exposure." Caries Research 52, no. 5 (2018): 367–77. http://dx.doi.org/10.1159/000486969.

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Objective: Changes in the protein profile of acquired enamel pellicles (AEP) formed in vivo over different time periods were evaluated after the application of hydrochloric acid (HCl). Methods: Nine subjects were submitted to dental prophylaxis with pumice. After 3 or 120 min, the teeth were isolated with cotton rolls and 50 μL of 0.1 M HCl (pH 1.0), 0.01 M HCl (pH 2.0), or deionized water were applied on the buccal surface of the teeth for 10 s. The AEP was then collected using an electrode filter paper presoaked in 3% citric acid. After protein extraction, the samples were submitted to reverse-phase liquid chromatography coupled to mass spectrometry (nano LC-ESI-MS/MS). Label-free quantification was performed (Protein Lynx Global Service software). Results: A total of 180 proteins were successfully identified in the AEP samples. The number of identified proteins increased with the time of pellicle formation. Only 4 proteins were present in all the groups (isoforms of IgA, serum albumin, and statherin). The greatest number of proteins identified uniquely in one of the groups was obtained for the groups treated with HCl after 2 h of pellicle formation (approx. 50 proteins). Conclusion: Proteins resistant to removal by HCl, such as serum albumin and statherin, were identified even in the short-term AEP. In addition, 120-min pellicles present many proteins that are resistant to removal by HCl. This suggests an increase in protection against intrinsic acids with the time of pellicle formation, which should be evaluated in future studies.
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