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1

Dempsey, Paula Jane. "Genetic and environmental contributions to morphological variation in the human permanent dentition : a study of Australian twins." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phd389.pdf.

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Bibliography: leaves 348-366. Elucidates the nature and extent of genetic and environmental contributions to variation in permanent tooth crown size. Sibling correlations are compared to find evidence of sex-linked genes contributing to crown size. This hypothesis was tested by comparing mean tooth size in female-male opposite-sex twins with same-sex twins, and singletons.
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2

McVeigh, Clare. "Variability in human tooth formation : a comparison of four groups of close biological affinity /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ66224.pdf.

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3

Cooper, Kayleigh Anne. "The physical characterisation and composition of archaeological dental calculus." Thesis, Cranfield University, 2017. http://dspace.lib.cranfield.ac.uk/handle/1826/12817.

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Dental calculus is a complex biological material that has been found to provide significant evidence of past population diet, health and habitual activity. It is composed of mineral phases, trace elements, organic species and can have inclusions such as starch granules and microfossils incorporated into its structure. This composition has been found to vary among individuals, although the reasons for this are poorly understood. Despite this, there is a wealth of knowledge that can be gained from analysing this biomineral, especially from archaeological remains. In past populations, the variables that affect composition, such as pharmaceuticals and diet are reduced compared to modern populations. As such the reliance on clinical studies that have investigated dental calculus from modern individuals, may be flawed when considering past populations. The focus of this study was to provide insight about the variation in physical characterisation and composition of archaeological dental calculus. Despite there being an abundance of archaeological dental calculus research, this is the first large scale compositional study of specimens from three separate past populations. In addition, this research is the first study to adopt a non-destructive to destructive approach to archaeological dental calculus analysis. As well, it is the first application of nanocomputed tomography to dental calculus from past populations. Consequently, this study demonstrates the first evidence of accumulation layering that has been detected using non- estructive nano-computed tomography. Furthermore, this research has identified three types of layering in archaeological dental calculus. Due to these findings, it is expected that this research will impact the future of dental calculus analysis, especially when considering dental calculus as a method of mapping an individual’s health, diet or lifestyle in the weeks or months prior to death. The overall results of this thesis demonstrate that some aspects of the morphological, mineralogical and elemental analysis of archaeological dental calculus are inconsistent with clinical literature. The results have also shown that there are some differences between the dental calculus from different archaeological populations which can be related to post-mortem burial conditions.
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4

MacDonald, Rachel Margaret. "In the teeth of the problem : dental anthropology and the reconstruction of African dietary regimes." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313588.

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5

Stephen, Soni. "Dental age determination in South Australian children : thesis submitted in partial fulfillment of the requirements for the degree of Master of Dental Surgery /." Title page, contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09DM/09dms831.pdf.

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6

Martin, Sarah Abigail. "Expression of fluctuating asymmetry in primate teeth: Analyzing the role of growth duration." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1366187797.

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7

Veneziano, A. "Big brains and small teeth : a primate comparative approach to dental and mandibular reduction in hominins." Thesis, Liverpool John Moores University, 2017. http://researchonline.ljmu.ac.uk/7451/.

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Within the genus Homo, we observe a decrease in mandibular robusticity and in the size of anterior and postcanine dentition, a trend that is usually referred to as reduction or gracilisation. Factors linked to diet, food processing and encephalization have been suggested to be the main drivers of this trend. Stone tools and fire would have allowed Pleistocene hominins to reduce food toughness, thus relaxing the selective pressures on the masticatory apparatus. In the Holocene, the changes in human lifestyle triggered by agriculture would have determined the reduction in human tooth size. Brain expansion may have acted as a constraint on the development of the lower jaw. In this work, a primate perspective was adopted to clarify the relative influence of adaptive and non-adaptive factors on mandibular and dental reduction in the genus Homo. The effect of diet and structural constraints (allometry and encephalization) on dental and mandibular size and robusticity were analysed. The results show that incisor size and mandibular robusticity correlate significantly with diet proxies in non-human extant catarrhines and with neurocranium shape changes in the neurocranium in Homo sapiens. In non-human African apes, the elongation of the neurocranium influences postcanine tooth size. In Homo, body size plays an important part in tooth size allometry, but not in robusticity. These results suggest that improvements in tool-based food preparation may have been a leading factor in the reduction of incisor size in hominins. Molars and premolars were probably influenced by the expansion of the neurocranium during Pleistocene, and incisor size may be constrained by neurocranium shape changes in H. sapiens. This work confirmed the importance of food processing in the trend of reduction and produced convincing evidence for the significance of structural constraints in the evolution of the hominin anatomy. These findings contribute to explain the complex evolution of the human skull.
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8

Avalos, Toby R. "Discerning hominid taxonomic variation in the southern Chinese, peninsular Southeast Asian, and Sundaic Pleistocene dental record." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5705.

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Today’s highly endangered orangutan populations of Sumatra and Borneo offer but a glimpse into the taxonomic diversity and vast regional distribution enjoyed by orangutans and their great ape relatives in East Asia over the past 2.5 million years—a time when tropical forest pongine habitats stretched from Java to southern China. In addition to the giant terrestrial ape Gigantopithecus, other great ape genera have been proposed to have existed within this hominid community. The taxonomic diversity of this great ape faunal array is even further complicated when the purported presence of hominins at Early Pleistocene sites older than 1.85 Ma is considered. Highly acidic, the jungle floors of East Asia are notoriously bad at fossil preservation decomposing skeletal and dental evidence quickly. Fortunately, ph-neutral limestone caves have acted to offset these forces. The outcome of this peculiar taphonomy has left us with many teeth, but very little bone. With only unassociated fossil dentition to work with, modern geometric morphometrics offers scientists one of the few cutting-edge tools capable of systematically assessing this material reliably. This dissertation applies modern geometric morphometric statistical analysis to over two thousand fossil hominid teeth (Appendix A) from the Quaternary of southern China and Southeast Asia, which offers unique insight into the taxonomic diversity present in this sole Pleistocene great ape community. This study provides a much clearer understanding of the composition, paleoecology, and regional distribution of Pleistocene great ape communities of East Asia. Concordant with previous research, the main study and pilot study conducted in this dissertation showed Homo sapiens to always be morphologically and statistically distinct from extant and fossil orangutans. In turn, Pongo pygmaeus and Pongo abelii were continuously shown to be distinct from each other as well as from fossil Pongo groups. This investigation refutes hominin assignments for several teeth previously placed within early East Asian hominins (showing them to be orangutans instead) but supports the hominin status of the Jianshi upper third premolar. In combination with a published age of 1.95–2.15 million years (Ma), the hominin assignment reaffirmed here for the Jianshi dentition originally classified as human by Liu, Clarke, & Xing (2010) may offer a challenge to evolutionary models that recognize the 1.85 Ma Dmanisi hominins as the earliest hominins outside of Africa. This fact is often lost on most contemporary scientists due to their preoccupation with the 2.5 Ma Longgupo mandibular fragment, once thought to be a hominin but now assignable to an ape. Like the Jianshi upper third premolar, it is also based on a single specimen (in this case, a mandibular fragment). This dissertation supports the existence of Ciochon’s (2009) “mystery ape”. It refutes Schwartz et al., (1995) multiple Vietnamese Pongo taxa, including the proposed genus “Langsonia,” which is reassigned here to Pongo or the “mystery ape,” while placing Vietnamese fossil orangutans into either Pongo weidenreichi or Pongo devosi. Teeth from the Ralph von Koenigswald collection originally assigned to “Hemanthropus” were also determined to be representative of either the “mystery ape” or Pongo. Indeterminate “hominin” teeth were assignable to either Homo erectus, Homo sapiens, or Pongo only; no evidence was found for any other types of hominin species present in the collections examined for this study.
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9

Patel, Nirdesh D. "Efficient prediction of bite fracture force for hard food items." Amherst, Mass. : University of Massachusetts Amherst, 2009. http://scholarworks.umass.edu/theses/228/.

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10

Townsend, Grant Clement. "Genetic studies of morphological variation in the human dentition /." Title page, contents, preface and overview only, 1994. http://web4.library.adelaide.edu.au/theses/09D/09dt748.pdf.

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11

Sutter, Richard C. "Dental variation and biocultural affinities among prehistoric populations from the coastal valleys of Moquegua, Peru, and Azapa, Chile /." free to MU campus, to others for purchase, 1997. http://wwwlib.umi.com/cr/mo/fullcit?p9841338.

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12

Nassar, Diaa Eldin M. "A prototype automatic dental identification system (ADIS)." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=1977.

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Thesis (M.S.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains v, 72 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 70-72).
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13

Lin, Jack Cheng-Wei, and n/a. "Electric pulp testing of molar teeth." University of Otago. School of Dentistry, 2007. http://adt.otago.ac.nz./public/adt-NZDU20071221.140417.

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Testing the vitality of teeth using electric pulp testers was reviewed. Two studies then investigated aspects of the application of electric pulp testing (EPT) to healthy first molar teeth. Twenty volunteers with first molars free of restorations and caries were recruited. One molar from each arch was selected and rubber dam applied. The tester probe was coated with fluoride gel. Seven sites on each crown were EPT tested four times, and all threshold responses recorded. Data were analysed using one way ANOVA at the 0.01 level. The lowest response for both the maxillary and mandibular teeth was with the probe on the mesio-buccal cusp tip. Males responded at a lower level than females at the mesio-buccal cusp tip, but this did not reach statistical significance. The relationship between pulp areas and dimensions on radiographs and the EPT results was investigated. Standardised bitewing radiographs of the tested molars were mounted and digitally scanned. Five measurements were taken using a computer program; crown width, the mesial and distal pulp horn heights, the area of the clinical crown, and the pulp area in the clinical crown. The four electrode placement sites with the lowest threshold from the pulp testing results were selected. Pearson correlations (2-tailed) were used to relate the measurements. There were no correlations between the coronal pulp size, pulp horn height and the probe placement site. The exception was an anomalous correlation between the distal horn height and mesio-buccal cuspal area of the maxillary molars.
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14

Walker, Richard Thomas. "A comparative investigation of the root number and canal anatomy of permanent teeth in a Southern Chinese population." Thesis, [Hong Kong : University of Hong Kong], 1987. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12335423.

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15

Tongkoom, Subongkoch. "The prevalence of dental anomalies in the primary dentition of Chinese children." [Hong Kong] : Faculty of Dentistry, the University of Hong Kong, 1994. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19902220.

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16

Lam, Raymond Hiu-wai. "Artificial teeth : dental biofilm analysis on a chip." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/62525.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2010.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>In this thesis, an "artificial teeth" microfluidic device is developed that provides unprecedented control over the conditions required to simulate the growth of complex dental biofilm. Dental plaque formation is not only a precursor to tooth decay, but also induces more serious systemic health problems such as cardiovascular disease, pre-term labor, and diabetes. Therefore, understanding the conditions promoting colonization and subsequent biofilm development involving complex bacteria coaggregation is particularly important. The requirement of the continuous culture and analysis systems for large quantities of growth media and reagents has pushed the move toward microfluidics - the miniaturization and chip-based control of fluidic operations. Microfluidic oxygenation is necessary to regulate the cellular gas condition of culture medium, especially for mixed population biofilms consisting of both anaerobic and aerobic cell populations. A double-layer gas perfusion network structure fabricated above the cell culture regions is developed for culture oxygenation. Throughout the modeling and analysis of the oxygen transfer in microfluidic oxygenators, design strategies for such devices are proposed for different configurations. Various designs of oxygen-nitrogen mixer networks providing parallel oxygenation with differential or tunable oxygen concentrations are described and verified experimentally to test the corresponding applicability in microbiological culture. The microfluidic "artificial teeth" platform, integrated with the microfluidic oxygenators, functions as an effective and inexpensive analysis tool to dynamically adjust critical growth parameters such as bacteria population, growth medium composition, medium flow rate and dissolved oxygen levels. The first single-chamber "artificial tooth" chip is developed for long-term dental biofilm culture with better medium handling, such as mixing, humidification and automated growth medium replenishment. This device is also compatible with different analysis techniques using optical microscopy in order to determine the biofilm thickness, the ratio between viable and dead cells, and the visualization of spatial distribution of different dental bacteria in the biofilm. Furthermore, the single-chamber design is extended to a device containing up to 128 chambers. This "artificial teeth" chip is developed to achieve high-throughput parallel biofilm culture and analysis with a matrix of different growth conditions that can contribute to the quantitative studies of the physiology of dental biofilms. The artificial teeth device is applied to investigate the response of two key dental bacteria, Streptococci sp. and Fusobacterium nucleatum, in the biofilm under different microenvironments, including their growth under different gas conditions and their adherence properties with different sucrose concentrations. This work demonstrates a successful application of microfluidics to long-term biofilm culture applications.<br>by Raymond H. W. Lam.<br>Ph.D.
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17

Alkharobi, Hanaa. "Characterisation of dental pulp cells derived from carious teeth." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/15341/.

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This study investigated some characteristics of dental pulp stromal/stem cells (DPSCs) isolated from healthy teeth (hDPSCs) compared to DPSCs isolated from teeth with shallow carious lesions (cDPSCs) with a view to the use of both cell types in hard tissue engineering strategies. Osteogenic differentiation was investigated using appropriate histochemical staining and osteogenic marker expression (ALPL, OC, RUNX-2). In addition, angiogenic (VEGFR-2, PECAM-1) and inflammatory gene markers (TLR-2, TLR-4) were investigated together with the secretion of the pro-inflammatory cytokines (IL-6 and IL-8). The activity of the pro-osteogenic IGF axis was also investigated in hDPSCs and cDPSC cultures. cDPSCs exhibited significantly higher clonogenic potential, and possess a higher proportion of cell that express mesenchymal stem cell markers (CD146+, CD90+ and CD105+, CD45-, CD31-) compared with hDPSCs. Evidence also suggested that cDPSCs had a greater osteoblastic differentiation potential than hDPSCs. cDPSCs expressed higher levels of inflammatory markers than hDPSCs together with higher concentrations of IL-6 and IL-8 in conditioned medium indicative of retention of a carious phenotype following cell isolation and culture. Finally functional examination of the IGF axis suggested a role for insulin-like growth factor binding proteins-2 and -3 (IGFBP-2 and -3) in the osteogenic differentiation of DPSCs. Therefore cDPSCs are comparable to hDPSCs in terms of their osteogenic potential and the inflammatory environment of cDPSCs may offer a promising cell source for future mineralised tissue repair and regeneration.
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18

Lee, Chun-kei, and 李鎮基. "Dental anomalies in the primary dentition." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B4715567X.

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Delayed diagnosis of dental anomalies in the permanent dentition can lead to severe occlusal, functional and aesthetic problems. Early diagnosis is not feasible in the primary dentition stage without screening radiography, which is controversial due to possible mutagenic effects. However, some dental anomalies in the primary dentition of Caucasians have been found to be followed by anomalies of the permanent successors. Therefore, identifying individuals at high risk of having anomalies of their permanent teeth by screening children for dental anomalies in the primary dentition, will facilitate early diagnosis and appropriate treatment. The objectives of this study were to determine the prevalence of dental anomalies in the primary dentition of a southern Chinese child population, and to investigate the relationship between the presence of a talon cusp, missing or supernumerary tooth in the primary dentition and the number of the permanent successor teeth. A total of 1513 children from 12 kindergartens were invited to participate in the prevalence study. School children visiting a regional school dental clinic during a four-year period and having talon cusp, supernumerary tooth or congenitally missing tooth in the primary dentition were included in the study to determine the relationship to the permanent successors. A total of 1333 children, aged from 2 years 11 months to 5 years 5 months (mean age 4 years 4 months) were included in the prevalence study. The prevalence of the commonest dental anomaly, double tooth, was 4.28%. Almost 95% of which were in the mandibular anterior region; one third of the double teeth involved the central and lateral incisors while the other two-thirds involved a lateral incisor and canine. The prevalence of congenitally missing teeth was 3.53%; all but one were mandibular incisors, the majority of which were lateral incisors. Girls were affected twice as often as boys. Both talon cusp and a supernumerary tooth occurred rarely (0.15%) and they were only found in the maxillary incisor region. A study of 57 cases of talon cusp on primary maxillary incisors showed that, when there was a talon cusp on the lateral incisor, 78.3% of the permanent successors exhibited odontogenic abnormalities; mostly in the form of supernumerary teeth. However, a talon cusp on a maxillary central incisor had no effect on the permanent successor. A study of 30 children with supernumerary primary teeth revealed that half of the children with supernumerary primary maxillary lateral incisors also had supernumerary permanent successors. A further study of 182 children with missing primary mandibular incisors showed that normal permanent successors were present in 50% of the cases with missing central incisors but only 8.5% of cases with missing lateral incisors. The prevalence of dental anomalies in the primary dentition of a local southern Chinese population differed from that of Caucasians. Children with talon cusp on primary maxillary lateral incisors, missing mandibular incisors and supernumerary maxillary lateral incisors were found to be at high risk of having an odontogenic abnormality in the permanent dentition. Clinicians should be aware of these anomalies and prepared to implement appropriate treatment.<br>published_or_final_version<br>Dentistry<br>Doctoral<br>Doctor of Philosophy
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19

Mullen, S. Russell. "Accuracy of performing space analysis using emodels[TM] and plaster models." Morgantown, W. Va. : [West Virginia University Libraries], 2004. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=3302.

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Thesis (M.S.)--West Virginia University, 2004.<br>Title from document title page. Document formatted into pages; contains vii, 56 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 36-39).
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20

Karkhanis, Shalmira. "Macroscopic and microscopic changes in incinerated deciduous teeth." University of Western Australia. Centre for Forensic Science, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0170.

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The teeth are amongst the most resilient elements of the human skeleton and are thus often utilised in routine forensic investigation involving the identification of unknown remains. The teeth, however, also have other practical forensic applications. Teeth exposed to thermal stress have the potential to not only aid in identification but also in understanding the circumstances surrounding the fire. Previous investigations have drawn conclusions that if a fire flares up suddenly and intensively, the teeth burst and enamel is lost. If the blaze commences gently and burns slowly, then the first observable morphologic change is the colour. The teeth subsequently are difficult to handle, thus changes in teeth can indicate the history of exposure to thermal conditions. Children are twice as likely to become victims of house fire because of an inability to safely evacuate from areas of danger. The literature demonstrates, however, that research on the effects of incineration on teeth is mostly restricted to the permanent teeth. The apparent lack of knowledge on the effects of incineration on deciduous teeth thus necessitates further research in this area. This research project primarily aims at understanding the effect of extreme temperatures on deciduous teeth. It also aims to relate colour changes that occur post heating with fragility to aid in proper handling of samples in a forensic scenario and to determine the possibility of identifying incineration temperature based on tooth condition. The samples analysed composed of 90 deciduous teeth (45 molars and 45 anteriors) extracted as a part of clinical treatment were used for the study. The project involved exposing extracted deciduous teeth to temperatures ranging from 100°C to 1100°C for 30 minutes using a laboratory Gallenkamp oven. Unheated deciduous teeth were used as controls for the project. Post-incineration the teeth were then analysed under a stereomicroscope and SEM for morphological changes. A colorimetric analysis was also undertaken to evaluate the colour changes induced in the primary teeth due to the thermal stress. It was found that it was possible to identify the incineration temperature based on the tooth condition when the colour changes, stereomicroscopic findings and SEM images were utilised collectively. It was also concluded that the thermally induced changes observed in primary teeth occur at lower temperatures in comparison to the permanent teeth. It was also established that post-incineration deciduous teeth are fragile and show a tendency to fragment after minimal exposure to thermal stress as compared to the permanent teeth. Moreover enamel and dentin remained identifiable in primary teeth even after exposure to 1100°C for 30 minutes while cementum lost its structural morphology at 900°C.
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21

TODESCAN, CARLA DI R. "Aplicacao de pulsos ultracurtos em esmalte dental bovino." reponame:Repositório Institucional do IPEN, 2003. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11252.

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22

Chan, Yee-loi, and 陳以來. "Nano-mechanical characterization of dental tissues." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44764480.

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23

Wong, Karen K. L. "Intra-pulpal thermal effects of dental lasers and high-intensity lights during light-activated tooth whitening and resin polymerisation on human teeth /." [St. Lucia, Qld.], 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16897.pdf.

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24

Leung, Sau-kuen. "Clinical evaluation of compomers used as restorations in primary teeth." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2120360X.

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OLIVEIRA, MARCELLA E. "Potencial de inibição da progressão de cárie artificial por irradiação sub-ablativa com laser de COsub(2) pulsado em esmalte dental bovino." reponame:Repositório Institucional do IPEN, 2005. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11288.

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Van, Der Poel Nadine Olive. "Mechanical retention of acrylic teeth onto a pure nylon base." Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/1536.

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Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Dental Technology in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology 2014<br>A pure nylon denture base does not bond chemically to the acrylic teeth processed into the denture. A mechanical bond is created by boring retention holes (diatorics) into the tooth structure. Concerns are that this form of retention might be insufficient. The purpose of this study is, firstly, to compare the retention of acrylic denture teeth in pure nylon dentures with that of teeth in conventional acrylic denture bases (the acrylic test pieces serving as the control standard), and secondly, to explore whether the technique prescribed for creating diatorics in acrylic teeth for use with pure nylon denture bases potentially has a weakening effect on the acrylic tooth structure. Two sets of 26 identical anterior one-tooth test pieces were created. The first set, labelled N, comprises two different pure nylon denture base materials labelled N1 and N2 – all have diatorics in the acrylic teeth. The second set, labelled A, comprised the same acrylic denture base. The set labelled A1 is the control standard without diatorics in the acrylic teeth and the set labelled A2 has diatorics within the acrylic teeth. A compressive load was applied to these test pieces at an angle of 45 degrees on the palatal surface of the tooth until fracture occurred or maximum load was reached. Resulting data from the first part of the research was analysed by One-Way ANOVA analysis. Resulting data for the second part of the research was analysed via the Chi-square cross- tabulation method. The One-Way ANOVA test revealed that there is no statistical difference in the mean fracture or maximum load in Newton values between the two A (acrylic denture base) groups. There is also no statistical difference in the mean fracture or maximum load in Newton values between the two N (pure nylon denture base) groups. There is, however, a statistically significant difference in the mean fracture or maximum load in Newton values of Group A in comparison to Group N. The Chi-square cross-tabulation indicated that the A groups have very similar breakage patterns, and the N groups have similar breakage patterns respectively. It is concluded that the mechanical retention of acrylic denture teeth in pure nylon denture bases is weaker than the mechanical and chemical retention of acrylic denture teeth in acrylic denture bases. It is also concluded that when diatorics are created as prescribed within the tooth, these do not weaken the tooth structure.
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Tongkoom, Subongkoch. "The prevalence of dental anomalies in the primary dentition of Chinesechildren." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1994. http://hub.hku.hk/bib/B31953980.

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28

Shabanian-Borojeni, Mitra. "Wear studies of enamel and some restorative materials." Title page, contents and summary only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phs5241.pdf.

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Includes bibliographical references (leaves [1-20]). A systematic analysis of wear involving the in vitro analysis of the wear of standard composite resin and glass ionomer cements restorations under controlled conditions; and, the qualitative and quantitative investigation of wear over a range of pH's and loads which might be encountered clinically in order to develop a "wear map" of the micromorphology of wearing teeth and restorations and a systematic modeling of wear rates.
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MULLER, KARIN P. "Efeitos da radiacao laser em baixa intensidade na prevencao da carie dental induzida em ratos." reponame:Repositório Institucional do IPEN, 2004. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11210.

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30

Liuti, Tiziana. "Morphological assessment of paranasal sinuses and teeth in the horse." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33192.

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Sinonasal and dental diseases can be a serious disorder in horses due to the persistence of the former and the common extension of the latter to the supporting bones of the skull. The diagnosis of equine sinonasal and dental disease can be challenging due to the complexity of these and adjacent anatomical structures, and therefore the use of advanced imaging, including computed tomography (CT) has greatly increased recently. A major aim of this study was to improve the morphological characterization of the sinuses and cheek teeth in normal horses of different ages. These studies defined the volumes of the 7 different sinus compartments; showed that the volume of the different compartments increase with age; that in contrast to accepted findings, the Triadan 09 alveoli is located in the caudal maxillary sinus (CMS) in 13% of the youngest group and the Triadan 10 alveoli is fully within the rostral maxillary sinus (RMS) in 53% of cases. The infraorbital canal was found to be susceptible to apical infection-related damage in horses < 2 years of age (< 2 y.o.) due to the intimate relationship of this canal and the medial aspect of the maxillary cheek teeth alveoli. The mean positions of the clinical crowns and apices of the maxillary Triadan 11s were 2.48 cm (adjusted 5.2% of head height) and 2.83 cm (adjusted 6.2% of head height) more rostral, respectively in horses >16 y.o. compared to horses < 6 y.o., consistent with rostral dental drift. Measurements of dental drift could provide further objective radiographic guidelines on ageing horses by dental imaging and also help our understanding of the aetiopathogenesis of cheek teeth diastemata. This study also found that the reserve crown length decreased from a mean of 4.7 cm (adjusted 19.7% of head height) in the youngest (< 6y.o.) group of horses to a mean of 2.9 cm (adjusted 10.5% of head height) in the oldest group (>15y.o.), with the 06s and 09s having the shortest reserve crowns. These data are useful reference information for clinicians and radiologists in the diagnosis and treatment of equine sinonasal and dental disease. Morphological characterization of the ventral and dorsal conchal bullae in horses of different age using CT described the age-related difference in sizes of these structures (smaller in younger horses). In the ventral conchal bulla, this reduction in volume was probably related to protrusion of the large dental alveoli in young horses into the nasal cavity and bulla. Bullae linear measurements and volumes were also associated with head size. The anatomical position of both bullae was associated with specific maxillary cheek teeth, thus increasing the diagnostic value of conventional radiography in the investigation of bulla disease and providing landmarks for the surgical treatment of this disorder. Skull shape analyzed with the use of Procrustes statistical analysis showed landmark variability between different age groups and in particular, high landmark variability between young (< 5y.o.) and old (>16y.o.) horses and less landmark variability between adult (6-15y.o.) and old horses. Future studies could investigate changes in the equine skull in relation to genotype to characterize breed-related diseases affecting teeth and sinonasal compartments. In the second part of the study, 32 infected maxillary cheek teeth extracted from clinical cases were evaluated grossly and histologically and these pathological results were compared to the pre-extraction radiographic and CT imaging findings. This study showed a high sensitivity (97%) of CT in detecting changes in teeth affected by apical infection. In the third part of the study, 30 cheek teeth assessed as being abnormal based on oral, radiographic and CT examinations were extracted along with their alveoli from 27 cadaver heads. Gross and histological examination findings from these teeth and alveoli were compared to the pre-extraction imaging findings, again showed high sensitivity (96.4%) of CT in diagnosing cheek teeth apical infection. Additionally, CT showed a high correlation with histology in detecting dental infection related alveolar bone changes including alveolar bone lysis, sclerosis and bone thickening. This aspect of the study was also the second largest pathological study of equine apical infection published to date and thus has also improved our understanding of the pathogenesis of this disorder. In conclusion, CT was shown to be an excellent imaging modality for improving the morphological characterization of the sinuses and teeth in normal horses of different ages, and thus also improving the value of this modality in diagnosis and treatment of disease affecting sinonasal and dental structures. This study also objectively showed the high sensitivity of CT in detecting cheek teeth apical infection in horses as compared to radiography, including by assessment of alveolar bone changes. Overall, the results of this project improve morphological knowledge of the equine skull and teeth and will have direct clinical benefits by improving the diagnosis and thus the treatment of equine sinonasal and dental disease.
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Oliveira, Fernando Toledo de. "Estimativa da idade cronológica por meio de avaliação radiográfica da mineralização de terceiros molares e altura do ramo da mandíbula." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/25/25132/tde-02062011-095629/.

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A estimativa da idade é um elemento importante na investigação antropológica, sendo uma das fontes preliminares dos dados para estabelecer a identidade de pessoas vivas ou restos mortais desconhecidos. Os métodos mais utilizados para este fim são os baseados no desenvolvimento ósseo e dentário dos indivíduos. Neste sentido, o presente trabalho apresentou como objetivo, estabelecer valores de referência na população brasileira para a estimativa da idade, por meio de dois métodos: a análise da mineralização dos terceiros molares; e a mensuração da altura do ramo mandibular. Para isso, foram escaneadas radiografias (407 panorâmicas e 289 cefalométricas em norma lateral) de pacientes, de 6 a 25 anos de idade, atendidos na Faculdade de Odontologia de Bauru. As imagens radiográficas panorâmicas foram utilizadas para análise da mineralização dos terceiros molares inferiores, através do método proposto por Demirjian, Goldstein e Tanner (1973), e as imagens radiográficas cefalométricas utilizadas para medir a altura do ramo da mandíbula. Os resultados indicam uma forte correlação entre a idade cronológica e ambos os métodos utilizados, proporcionando a elaboração de fórmulas para o cálculo da idade aproximada dos indivíduos na população estuda. Não houve diferença estatisticamente significante para o desenvolvimento dos terceiros molares entre os sexos. Já para a altura do ramo da mandíbula, essa diferença ocorreu entre os 16 e 25 anos de idade. A probabilidade de afirmamos que um indivíduo tem 18 anos ou mais de idade, com base nas duas metodologias proposta neste trabalho, é extremamente alta (>90%). Concluiu-se que ambos os métodos estariam aptos a serem utilizados para estimar a idade na população brasileira, entretanto, pelo fato do Brasil ser um país com extenso território e apresentar uma população bastante miscigenada, novos estudos devem ser realizados, aumentando a amostra dessa população, e permitindo o aprimoramento dos valores aqui informados.<br>Age determination is an important element in anthropological research, one of the primary sources of data to establish the person living identity or unknown remains. The aim of this paper was to establish reference values in Brazilian population to estimate chronological age by two methods: mineralization of third molars and measurement of the mandible ramus height. Therefore, radiographs from patients between 6 to 25 years, were scanned (407 panoramics and 289 cephalometrics). The patients were from School of Dentistry at Bauru. The panoramic radiographs were used for analysis the mineralization of the mandibular third molars. Moreover, cephalometric radiographs were used to measure the mandibular height. The results indicated a strong correlation between chronological age and both methods, providing the development of formulas for calculating the approximate real age of individuals by radiographs. There was no statistically significant difference for the third molars development between sexes. There was a significant difference between men and women for ramus height of the mandible for the range between 16 and 25 years. The probability of a claim that an individual is 18 years or older, based on the two methodologies proposed in this work was extremely high (>90%). It was concluded that both methods were suitable to be used to estimate the age in Brazilian population. However, as Brazil is a country with vast territory and present a fairly mixed population, it is necessary further studies to confirm the values reported.
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CARA, ANA C. B. de. "Avaliação do processo de desenvolvimento de desmineralização em esmalte dental humano utilizando a técnica de tomografia por coerencia óptica." reponame:Repositório Institucional do IPEN, 2012. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10112.

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Made available in DSpace on 2014-10-09T12:34:53Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:08:10Z (GMT). No. of bitstreams: 0<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Dissertação (Mestrado)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP<br>FAPESP:10/03123-8
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Mubarak, Suhayla Walsh Laurence J. "Design, implementation and assessment of an instructional cd-rom in dental radiology /." [St. Lucia, Qld.], 2001. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16692.pdf.

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34

Al-Mohammadi, Saeed M. "An investigation into factors related to developmental defects of enamel in Saudi children." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283018.

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35

Amaechi, Bennett Tochukwu. "Studies relating to the development and progression of enamel lesions : caries and erosion." Thesis, University of Liverpool, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366453.

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36

Lam, Garret Chi Yan. "Biomechanics of orthodontic tooth movement /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?MECH%202003%20LAM.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 118-122). Also available in electronic version. Access restricted to campus users.
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37

Dahmer, Heidi L. "The effects of toothbrush design on bacterial retention and viability a preliminary study /." Morgantown, W. Va. : [West Virginia University Libraries], 1998. http://etd.wvu.edu/templates/showETD.cfm?recnum=308.

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Thesis (M.S.)--West Virginia University, 1998.<br>Title from document title page. Document formatted into pages; contains vii, 72 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 56-58).
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38

Bloomquist, Ryan F. "Developmental plasticity of stem cells in teeth and taste bud renewal." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/53565.

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Science and medicine have progressed in unfathomable ways over the past century. Paradoxically, as our result of our advancements in medicine we live in a progressively aging society where the majority of people will have multiple morbidities associated with senescence. The World Health Organization estimates that nearly 100% of the population will suffer dental maladies, which left untreated compound with age. We hope to gain new biomedical insight applicable to the advancing field of dental regenerative therapeutics. This dissertation reveals new dental biology through studying the embryology, genetics and evolution of teeth across patterning, morphogenesis and regeneration. We exploit an innovative model, the Lake Malawi cichlid fishes, to study these processes in a natural system. Malawi cichlids have rapidly evolved diverse species-specific dentitions, ranging from hundreds to thousands of teeth that represent a rainbow of shapes and sizes, yet Malawi cichlid species has nearly identical genomes, offering us a powerful genetic system. Furthermore, unlike classic vertebrate models in embryology such as zebrafish, chicken or mice, cichlids have oral teeth and the ability to replace each tooth constantly throughout their lifetimes. In the first study, we break-down the process of whole de-novo tooth replacement in cichlids. We then explore the re-deployment of initiating gene pathways later in the morphogenesis of each replacement tooth (RT). In the second study we investigate the co-patterning of two placode derived oral organs, teeth and taste buds (TBs), and uncover new genes that may modulate their number and size. We subsequently discover a bipotency of progenitor tissue to form both organs and a later plasticity to trans-fate it through coordination of a Wnt-BMP- Hh genetic hierarchy. In the last study, we explore the stem cells that are responsible for the phenomenon of lifelong cichlid tooth replacement. We describe a common epithelium connected to TBs and rich in stem cells, with a newly discovered stem cell niche at the tip of the RT. We uncover the transcriptomes of both organs, and through differential gene expression informed manipulations, coerce dental cells to display TB characteristics. We hypothesize that TB stem cells may be used in dental therapeutics.
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39

Lang-Hua, Bich Hue, and 梁許碧蕙. "Decision-making in dental treatment planning: to maintain or to extract compromised teeth." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B50534282.

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Background: A number of systematic reviews provide the basis for decision-making in treatment planning of the reconstruction of mutilated dentitions. This includes identifying teeth difficult to treat/save and decisions on replacement such teeth if extracted. Aims: 1) To assess attitudes of general dental practitioners (GDPs) in a community where provision of dental implants is a widely practiced treatment; and to determine variations in attitudes with respect to dentists’ factors, training factors and implant-provision factors (Study 1): and 2) To determine treatment decision making with respect to maintaining periodontally compromised teeth among dentists with and without postgraduate qualifications in implant dentistry (Study 2). Methods: Study 1:A cross-sectional survey was conducted on a random sample of registered dentists in Hong Kong regarding their attitudes towards implant dentistry with respect to (1) perceived superiority, (2) perceived outcomes, (3) perceived complications and maintenance issues and (4) placement issues. In addition, information was collected on dentists’ factors, training factors and implant provision factors. Variations in attitudes towards implant dentistry were explored. Study 2: A series ofpatient scenarios with varying degrees of periodontal disease levels was presented to selected dentists. Information on their decision-making outcomes, and their intention to retain compromised teeth was analysed in bivariate and regression analyses; accounting for postgraduate implant training, gender, years in dental practice and implant placement experience. Results: Study 1: Among eligible practitioners (n=246), the response rate was 46.3%. Most dentists’perceived implants to be superior to conventional prostheses for the replacement of a single missing posterior tooth (80%) and likewise, for the replacement of a single missing anterior tooth (67%). Variations in attitudes existed with respect to dentists’ factors: years in practice (p<0.05), place of graduation (p<0.05); implant training factors (p<0.05), number of days of training (p<0.05) and implant experience factors (p<0.05). Study 2:This study involved 30 dentists with postgraduate implant qualifications (GDPP), 33 dentists without postgraduate implant qualifications (GDP) and 27 dentists undergoing postgraduate training for implant qualifications (GDPT). Variations in treatment decision-making were evident between the three groups (p<0.05). Differences in treatment approaches to retaining compromised teeth were apparent(p<0.05). Furthermore, variations in rehabilitation of extracted scenarios existed in terms of use of implants and number of implants needed for rehabilitation. Accounting for dentist and practice factors in regression analyses, compared to GDP, GDPP/GDPT were three times as likely to retain periodontally compromised upper molars with painwith pain (OR 3.08, 95%CI 1.09, 8.14 p=0.03), or without pain (OR 3.10, 95%CI 1.04, 10.62 p=0.04). Conclusions: Study 1:In a community where provision of dental implants is widespread the attitudes of GDPs are not wholly in line with evidence-based knowledge. Variations in their attitudes exist with respect to dentist factors, training and experience issues. Study 2: Variations in treatment decision making with respect to retaining periodontally compromised teeth exist between dentists with and dentists without postgraduate training in implant dentistry. Furthermore, there are differences in their management approaches.<br>published_or_final_version<br>Dentistry<br>Master<br>Master of Philosophy
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Evans, Dafydd James Parry. "The vitality assessment of traumatised permanent anterior teeth using laser dopppler flowmetry." Thesis, University of Glasgow, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295319.

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41

Ho, Wai-mei. "A microbiological study of endodontically treated teeth associated with asymptomatic peri-radicular rarefaction." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/HKUTO/record/B38628387.

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42

Nguyen, Hai Ngoc. "The mandibular canal at the region of the molar teeth." Connect to full text, 2008. http://hdl.handle.net/2123/4417.

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Thesis (M. Sc. Dent.)--University of Sydney, 2009.<br>Title from title screen (viewed Aug. 11, 2009) Submitted in fulfilment of the requirements for the degree of Master of Science in Dentistry to the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry. Degree awarded 2009 ; thesis submitted 2008. Includes bibliographical references. Also available in print form.
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43

BRANCO, ELOISA P. "Estudo comparativo da cor dental, in vivo, entre clareamentos sem aceleraçao, acelerado por LED e por laser, com análise dos resultados imediatos e a longo prazo." reponame:Repositório Institucional do IPEN, 2006. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11699.

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Made available in DSpace on 2014-10-09T12:54:53Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:07:04Z (GMT). No. of bitstreams: 1 12797.pdf: 513559 bytes, checksum: 4b6e71bdbea803b32a3222d0b42f7b13 (MD5)<br>Dissertacao (Mestrado Profissionalizante em Lasers em Odontologia)<br>IPEN/D-MPLO<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP; Faculdade de Odontologia, Universidade de Sao Paulo, Sao Paulo
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44

Bartlett, David W. "The relationship between gastro-oesophageal reflux and palatal dental erosion." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307585.

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45

Benedicto, Eduardo de Novaes. "Validação de três métodos para estimativa de idade de crianças e adolescentes brasileiros." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/23/23153/tde-27112017-111916/.

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A estimativa de idade é um importante recurso em Odontologia Legal. Entre as diversas formas de se obter uma estimativa de idade, pesquisadores podem fazê-la por meio da análise do estágio de mineralização dos dentes permanentes. Este tipo de análise, torna possível que uma simples radiografia panorâmica possa fornecer dados relevantes para identificar um indivíduo falecido, por exemplo. Este estudo propõe a validação, análise da acurácia e a construção de fórmulas baseadas nos métodos de Liliequist e Lundberg com a adaptação de Hägg e Matsson (LLH), Haavikko (HKK) e Mornstad et al. (MSW) para a estimativa de idade pelo estágio de mineralização dos dentes permanentes em crianças e adolescentes brasileiros. Para alcançar este resultado, foram selecionadas radiografias panorâmicas de brasileiros em uma amostra contendo 1.009 radiografias (387 do sexo masculino e 622 do sexo feminino) com idade entre 8-15,99 anos. Destas radiografias, foram selecionadas apenas as que cumpriram com todos os requisitos dos critérios de inclusão e exclusão. Após a aplicação das metodologias, os resultados foram inseridos e trabalhados no Programa Excel, Pacote Estatístico STATA 13.0. (StataCorp LP, College Station, Texas, EUA) e MedCalc (Medcalc® Software, Mariakerke, Bélgica) de acordo com as necessidades do estudo. As amostras foram divididas sem distinção quanto ao sexo, com distinção quanto ao sexo, e com distinção quanto ao sexo e idade. A comparação dos métodos foi realizada pela diferença de médias da idade dentária com a idade cronológica (ID-IC). A acurácia foi analisada pela Diferença Absoluta (DA). O teste normalidade de Skewness e Kurtosis foi empregado e, dependendo do resultado, os dados foram submetidos ao Test t de Student, ou ao teste de Wilcoxon, para amostras pareadas. Como resultado das comparações sem qualquer distinção quanto ao sexo, a melhor acurácia foi obtida por LLH (DA = 0,97 e ID-IC = 0,58), HKK (DA = 1,42 e ID-IC = -1,35) e MSW (DA = 2,48 e ID-IC = 3,08). Com distinção quanto ao sexo, os valores para o masculino foram: LLH (DA = 0,91 e ID-IC = -0,45), HKK (DA = 1,80 e ID-IC = -1,75) e MSW (DA = 2,74 e ID-IC = 1,17); e para o feminino LLH (DA = 1,01 e ID-IC = -0,67), HKK (DA = 1,17 e ID-IC = -1,09) e MSW (DA = 2,31 e ID-IC = 0,53). Na comparação com distinção entre sexo e idade houve um predomínio respectivamente da técnica de LLH, seguida de HKK e MSW. As equações de regressão aplicadas na mesma amostra apresentaram em média DA = 0,72 e ID-IC = -0,01. Também, algumas fórmulas de regressão múltipla foram construídas a partir dos dados apresentados para as metodologias de LLH e HKK, exceto para MSW que não forneceu dados suficientes para o software criar equações. Ao final, foi possível concluir que é possível a validação das metodologias apresentadas para a população brasileira e que a metodologia que mais se aproximou da população brasileira foi o método de Liliequist e Lundberg com a adaptação de Hägg e Matsson.<br>Age estimation is an important resource in Forensic Dentistry. Among several ways to obtain the age estimation, researchers may do it by analyzing the mineralization stage of permanent teeth. This type of analysis allows that a simple panoramic radiograph to provide relevant data to identify a deceased individual, for example. This study proposes the validation, accuracy analysis and construction of formulas based on the methods Liliequist and Lundberg with the adaptation of Hägg and Matsson (LLH), Haavikko (HKK) and Mornstad et al. (MSW) for the estimation of age by the stage of mineralization of permanent teeth in Brazilian children and adolescents. To achieve the results, panoramic radiographs of Brazilians were selected in a sample containing 1009 radiographs (387 males and 622 females) aged 8-15.99 years. Of these radiographs, it was selected only those that fulfilled all the requirements of the inclusion and exclusion criteria. After applying the methodologies, the results were inserted and worked in the Excel Program, Statistical Package STATA 13.0. (StataCorp LP, College Station, Texas, USA) and MedCalc (Medcalc® Software, Mariakerke, Belgium) according to the needs of the study. The samples were divided without splitting sex, with splitting sex and with splitting sex and age. The comparison of methods was performed by the mean differences between dental age and chronological age (DA-CA). Accuracy was analyzed by Absolute Difference (AD). The Skewness e Kurtosis normality test was employed and the Student t test, or the Wilcoxon test, for paired samples was submitted depending on the results. The results of comparisons informed, without any distinction as to sex, the best accuracy was obtained by LLH (AD = 0.97 and DA-CA = 0.58), HKK (AD = 1.42 and DA-CA = -1.35) and MSW (AD = 2.48 and DA-CA = 3.08). With distinction to sex the values for male were: LLH (AD = 0.91 and DA-CA = -0.45), HKK (AD = 1.80 and DA-CA = -1.75) and MSW (AD = 2.74 and DA-CA = 1.17); and for female: LLH (AD = 1.01 and DA-CA = -0.67), HKK (AD = 1.17 and DA-CA = -1.09) and MSW (AD = 2.31 and DA-CA = 0.53). In the comparison with distinction between sex and age, there was a predominance of the LLH technique, followed by HKK and MSW, respectively. The regression equations applied in the same sample presented mean AD = 0.72 and DA-CA = -0.01. In addition, some multiple regression formulae were constructed from the data presented for LLH and HKK methodologies, except for MSW, which did not provide enough data for the software to create equations. At the end, it was possible to conclude that it is possible to validate the methodologies presented in the Brazilian population and the methodology that most approached the Brazilian population was the Liliequist and Lundberg method with the adaptation of Hägg and Matsson.
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46

何慧美 and Wai-mei Ho. "A microbiological study of endodontically treated teeth associated with asymptomatic peri-radicular rarefaction." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B38628387.

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47

Sulkala, M. (Merja). "Matrix metalloproteinases (MMPs) in the dentin-pulp complex of healthy and carious teeth." Doctoral thesis, University of Oulu, 2004. http://urn.fi/urn:isbn:9514274598.

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Abstract The dentin-pulp complex comprises mineralized dentin and the vital soft tissues encased inside dentin, i.e. odontoblasts and pulp tissue. During caries progression, the dentinal minerals are dissolved and eventually the collagenous organic matrix is degraded. However, the exact mechanisms and enzymes responsible for the organic matrix breakdown remain unknown. Matrix metalloproteinases (MMPs), a family of endopeptidases capable of degrading in concert virtually all extracellular matrix components, are expressed during normal dentin-pulp complex formation and maintenance. MMP activity has also been suggested to contribute to the organic matrix degradation during dentin caries progression and to the repair and defense reactions elicited by caries in the dentin-pulp complex cells. The aim of the study was to further elucidate the role of host MMPs in dentin caries progression and the origin of MMPs in carious dentin as well as the possible changes in MMP expression in the cells of the dentin-pulp complex in response to caries. MMP inhibitors decreased the area of dentin caries lesions in vivo, suggesting the involvement of host MMPs in dentin caries pathogenesis. When the overall MMP gene expression was examined by cDNA microarray, pooled pulp samples demonstrated a high level of MMP-13 expression, but failed to show any unequivocal changes in MMP expression due to caries. MMP-13 expression is rare among normal human adult tissues. Real-time quantitative PCR of individual pulp and odontoblast samples demonstrated a rather large variation in relative MMP-13 mRNA expression between samples, especially pulp samples. Protein expression of MMP-13 was detected in pulp and odontoblasts without any major differences between the tissues of sound and carious teeth. This was also the case with the MMP-20 (enamelysin) protein, which was demonstrated in odontoblasts and the pulp tissue of fully developed human teeth. MMP-20, MMP-8, and gelatinases (especially MMP-2) were demonstrated in human dentin, and dentinal MMPs exhibited activity against native and denatured type I collagen when released. The study demonstrates the presence of MMPs in the soft and hard tissue compartments of the dentin-pulp complex. These enzymes may also contribute to dentin caries progression and response reactions to caries.
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48

Chan, Chi-lap Samuel. "Caries prevalence and feeding habits of toddlers in Hong Kong." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/HKUTO/record/B38628375.

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49

Richardson, Charlotte Jane. "Benign design for dental restorations." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327645.

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50

Amjad, Shwan. "Endodontic complications in vital teeth restored with composite resins: a systematic review." Thesis, Malmö högskola, Odontologiska fakulteten (OD), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-19702.

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Abstract:
Syftet med den här systematiska litteraturöversikten var att ta reda på om vitala tänder restaurerade med kompositmaterial har högre risk för att utveckla endodontiska komplikationer över tid såsom apikal parodontit eller smärta i jämförelse med tänder som restaurerats med andra dentala fyllningsmaterial som amalgam. Komposit används ofta som ett fyllningsmaterial och även om man studerat kompositers påverkan på t.ex. pulpaceller och funnit att det inte är helt oskadligt är det oklart om materialet faktiskt påverkar pulpan och leder till endodontiska komplikationer. Genomförandet av systematiska litteraturöversikten omfattade (i) formulering av frågeställning, (ii) konstruktion och genomförande av litteratursökning med (iii) tolkning och värdering av den identifierade litteraturen. Den initiala sökningen i databasen PubMed gav 938 publikationer som granskades oberoende av tre personer. Efter ytterligare sökningar kvarstod totalt tio studier som inkluderades i den systematiska litteraturöversikten. Alla inkluderade studier bedömdes ha ett lågt bevisvärde vilket ledde till att ingen konklusion med evidensgrad kunde ges. De inkluderade studierna rapporterar få, om ens några, endodontiska komplikationer och få eller inga skillnader rapporterades vid tänder restaurerade med komposit jämfört med amalgam. Fler väl genomförda studier med ett stort antal patienter krävs för att svara på frågan om tänder restaurerade med kompositmaterial har högre risk för att utveckla endodontiska komplikationer i jämförelse med andra dentala fyllningsmaterial.
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