Relevant bibliographies by topics / Telmisartan is pharmacologically active molecule

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Academic literature on the topic 'Telmisartan is pharmacologically active molecule'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Telmisartan is pharmacologically active molecule"

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Premchand, Patil Deepak V. Nagarale and Bhata R. Chaudhari*. "RECENT ADVANCES AND APPLICATIONS OF TELMISARTAN." Indo American Journal of Pharmaceutical Sciences 04, no. 10 (2017): 3935–45. https://doi.org/10.5281/zenodo.1035249.

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Telmisartan is pharmacologically active molecule, Here we reviewed some synthetic methods and their application like angiotensin II receptor, quantitative determination for the biological activity using NMR, restrict NFAT nuclear translocation and etc..
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Pingali, Subramanya, James P. Donahue, and Florastina Payton-Stewart. "Tetrahydroberberine, a pharmacologically active naturally occurring alkaloid." Acta Crystallographica Section C Structural Chemistry 71, no. 4 (2015): 262–65. http://dx.doi.org/10.1107/s2053229615004076.

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Tetrahydroberberine (systematic name: 9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-benzo[g][1,3]benzodioxolo[5,6-a]quinolizine), C20H21NO4, a widely distributed naturally occurring alkaloid, has been crystallized as a racemic mixture about an inversion center. A bent conformation of the molecule is observed, with an angle of 24.72 (5)° between the arene rings at the two ends of the reduced quinolizinium core. The intermolecular hydrogen bonds that play an apparent role in crystal packing are 1,3-benzodioxole –CH2...OCH3and –OCH3...OCH3interactions between neighboring molecules.
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Motterlini, Roberto, Philip Sawle, Sandip Bains, et al. "CORM‐A1: a new pharmacologically active carbon monoxide‐releasing molecule." FASEB Journal 19, no. 2 (2004): 1–24. http://dx.doi.org/10.1096/fj.04-2169fje.

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Parmar, Dixit, Lena Henkel, Josef Dib, and Magnus Rueping. "Iron catalysed cross-couplings of azetidines – application to the formal synthesis of a pharmacologically active molecule." Chemical Communications 51, no. 11 (2015): 2111–13. http://dx.doi.org/10.1039/c4cc09337b.

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A protocol for the cross-coupling of azetidines with aryl, heteroaryl, vinyl and alkyl Grignard reagents has been developed under iron catalysis. In addition, a short formal synthesis of a pharmacologically active molecule was demonstrated.
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Patel, Navin B., and Imran H. Khan. "Synthesis of 1,2,4-triazole derivatives containing benzothiazoles as pharmacologically active molecule." Journal of Enzyme Inhibition and Medicinal Chemistry 26, no. 4 (2011): 527–34. http://dx.doi.org/10.3109/14756366.2010.535794.

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Terekhova, Irina, Iliya Kritskiy, Mikhail Agafonov, Roman Kumeev, Carlos Martínez-Cortés, and Horacio Pérez-Sánchez. "Selective Binding of Cyclodextrins with Leflunomide and Its Pharmacologically Active Metabolite Teriflunomide." International Journal of Molecular Sciences 21, no. 23 (2020): 9102. http://dx.doi.org/10.3390/ijms21239102.

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The selectivity of encapsulation of leflunomide and teriflunomide by native α-, β- and γ-cyclodextrins was investigated through 1H NMR and molecular modeling. Thermodynamic analysis revealed the main driving forces involved in the binding. For α-cyclodextrin, the partial encapsulation was obtained while deep penetration was characterized for the other two cyclodextrins, where the remaining polar fragment of the molecule is located outside the macrocyclic cavity. The interactions via hydrogen bonding are responsible for high negative enthalpy and entropy changes accompanying the complexation of
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Manish S. Junagade and Anju Goyal. "‘Mutual Prodrug’ and approach to increase the effectiveness of Non-Steroidal Anti-inflammatory Drugs." World Journal of Biological and Pharmaceutical Research 1, no. 1 (2021): 035–45. http://dx.doi.org/10.53346/wjbpr.2021.1.1.0011.

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A clinically useful drug may have limitations in practice because of undesirable side effects, poor solubility, and poor bioavailability, short duration of action, first-pass effect, poor absorption & adverse effects. There are increased efforts in research to increase the therapeutic efficacy of drugs by eliminating or minimizing the undesirable properties of drug molecules. Some of the problems can be solved using a formulation development approach but in some cases, chemical modification in the molecule is necessary to correct the pharmacokinetic parameters. One of the approaches to con
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Manikkam, Rajalakshmi. "Molecular docking analysis of quercetin with known CoVid-19 targets." Bioinformation 19, no. 11 (2023): 1081–85. http://dx.doi.org/10.6026/973206300191081.

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Combat and care during CoVid-19 was non-trivial. Therefore, it is of interest to use the pharmacologically active plant component quercetin for the treatment of CoVid-19. Quercetin exhibits favourable ADMET values and abides by Lipinski's rule of five. When quercetin and remdesivir were positioned in relation to the CoVid-19 targets, quercetin exhibited a greater propensity for binding and H-bond interaction in their molecular interactions. Thus, the quercetin molecule can be used to manage CoVid-19.
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Jiao, Luzhen, Dawei Teng, Zixuan Wang, and Guorui Cao. "Silver Catalyzed Site-Selective C(sp3)−H Bond Amination of Secondary over Primary C(sp3)−H Bonds." Molecules 27, no. 19 (2022): 6174. http://dx.doi.org/10.3390/molecules27196174.

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Sulfamates are widespread in numerous pharmacologically active molecules. In this paper, Silver/Bathophenanthroline catalyzed the intramolecular selective amination of primary C(sp3)−H bonds and secondary C(sp3)−H bonds of sulfamate esters, to produce cyclic sulfamates in good yields and with a high site-selectivity. DFT calculations revealed that the interaction between sulfamates and L10 makes the molecule more firmly attached to the catalyst, benefiting the catalysis reaction. The in vitro anticancer activity of the final products was evaluated in MCF-7 breast cancer cells.
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Kiseleva, E. A., S. G. Krylova, T. N. Povet`eva, et al. "Study Into Antinociceptive Activity of a New Molecule from the Class of Hexaazaizowurzitane." Journal Biomed 19, no. 1 (2023): 61–72. http://dx.doi.org/10.33647/2074-5982-19-1-61-72.

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In this work, we studied the pharmacological activity of a newly-synthesized compound 4-(3,4- dibromothiophenylcarbonyl)-10-(2-ethoxyacetyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,03,11,05,9]dodecane (M3) using somatogenic pain models of various genesis (thermal and visceral pain, mechanical compression of a paw). The compound showed a high antinociceptive efficacy, comparable to or exceeding that of tramadol. It was shown that the new molecule from the class of hexaazaisowurtzitane effectively blocks nociceptive reactions at the supraspinal and peripheral levels of pain se
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Book chapters on the topic "Telmisartan is pharmacologically active molecule"

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Karolak-Wojciechowska, Janina. "Utilization of crystallographic results for selecting and designing pharmacologically active compounds." In Correlations, transformations, and interactions in organic crystal chemistry. Oxford University PressOxford, 1994. http://dx.doi.org/10.1093/oso/9780198558262.003.0010.

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Abstract In the model presented for the utilization of crystallographic results, the atomic coordinates in the crystal structure are used as a starting point for searching for the conformation of a molecule that would correspond to the energy minimum (or several minima). It is assumed that this would be a conformation close to that existing in solution. To attain this aim it is necessary to carry out. Crystallographic analysis of the chosen compounds. Conformational analysis of the molecules by means of the molecular mechanics method. Molecular-orbital optimization of the geometry of all molec
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G, Jaya Syamala, and Satya Sree B. "PRODRUG DEVELOPMENT." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 1. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn1p1ch1.

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Since from the late 19th century, Prodrug approach has been used to enhance undesirable drug characteristics, Adrien Albert first used the term "Prodrug" at the end of the 1950s to describe drugs that are inactive on their own but transform into an active derivative through biotransformation in 1958. In 1959, Harper finished the idea and coined the phrase called "drug latentiation" to describe medications that need bioactivation was first used [1]. Acetanilide was originally used as a Prodrug in 1867 by Cahn and Hepp, who also brought it to medicine. The biologically active molecule acetaminop
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Journal articles
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