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Journal articles on the topic 'Temporal lobe epilepsey'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Krishnamurthy, K. B., A. Blum, J. R. Ives, A. Goldberger, and D. L. Schomer. "Asystole as a manifestation of temporal lobe epilepsey." Electroencephalography and Clinical Neurophysiology 102, no. 1 (1997): P23. http://dx.doi.org/10.1016/s0013-4694(97)86318-3.

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Eckert, M. A., Tim Lucas, D. Rowers, C. M. Leonard, R. Quislino, and R. L. Gilmore. "Hippocampal MR volumes as a function of onset and duration in patients with left temporal lobe epilepsey." Electroencephalography and Clinical Neurophysiology 102, no. 1 (1997): P23. http://dx.doi.org/10.1016/s0013-4694(97)86317-1.

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Franzon, Renata C., and Marilisa M. Guerreiro. "Temporal lobe epilepsy in childhood: review article." Journal of Epilepsy and Clinical Neurophysiology 12, no. 1 suppl 1 (2006): 26–31. http://dx.doi.org/10.1590/s1676-26492006000200006.

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INTRODUCTION: The authors present a review article on temporal lobe epilepsy in childhood. METHODS: We performed a search in the literature. RESULTS: The main etiologies of temporal lobe epilepsy in childhood are developmental tumors and focal cortical displasia, besides temporal medial sclerosis. The clinical features may be variable particularly in children younger than six years of age. Epilepsy may present with generalized seizures. Electroencephalographic findings are also variable and show a functional dysfunction of several brain areas besides temporal lobes, especially frontal lobes. C

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Labate, Angelo, Regula S. Briellmann, Anthony S. Harvey, et al. "Temporal lobe dysembryoplastic neuroepithelial tumour: significance of discordant interictal spikes." Epileptic Disorders 6, no. 2 (2004): 107–14. http://dx.doi.org/10.1684/j.1950-6945.2004.tb00057.x.

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ABSTRACT Purpose: Dysembryoplastic neuroepithelial tumours (DNET) are an important cause of refractory partial epilepsies. They usually occur within dysplastic cortex and tend to affect the temporal lobes. The EEG of these patients is characterised by slowing and/or epileptiform abnormalities with a multifocal distribution. We studied the EEG features of epilepsy patients with a temporal lobe DNET to assess the relationship of EEG abnormalities with the localisation of the tumour and the clinical features. Methods We retrospectively reviewed 16 patients with unilateral, temporal lobe DNET on M

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Grassia, Fabio, Andrew V. Poliakov, Sandra L. Poliachik, et al. "Changes in resting-state connectivity in pediatric temporal lobe epilepsy." Journal of Neurosurgery: Pediatrics 22, no. 3 (2018): 270–75. http://dx.doi.org/10.3171/2018.3.peds17701.

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OBJECTIVEFunctional connectivity magnetic resonance imaging (fcMRI) is a form of fMRI that allows for analysis of blood oxygen level–dependent signal changes within a task-free, resting paradigm. This technique has been shown to have efficacy in evaluating network connectivity changes with epilepsy. Presurgical data from patients with unilateral temporal lobe epilepsy were evaluated using the fcMRI technique to define connectivity changes within and between the diseased and healthy temporal lobes using a within-subjects design.METHODSUsing presurgical fcMRI data from pediatric patients with un

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Valente, Kette D. R., and Geraldo Busatto Filho. "Depression and temporal lobe epilepsy represent an epiphenomenon sharing similar neural networks: clinical and brain structural evidences." Arquivos de Neuro-Psiquiatria 71, no. 3 (2013): 183–90. http://dx.doi.org/10.1590/s0004-282x2013000300011.

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The relationship between depression and epilepsy has been known since ancient times, however, to date, it is not fully understood. The prevalence of psychiatric disorders in persons with epilepsy is high compared to general population. It is assumed that the rate of depression ranges from 20 to 55% in patients with refractory epilepsy, especially considering those with temporal lobe epilepsy caused by mesial temporal sclerosis. Temporal lobe epilepsy is a good biological model to understand the common structural basis between depression and epilepsy. Interestingly, mesial temporal lobe epileps

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Ribbeck Lourdes, Simbrón, Sandoval Paredes Josefina, Amador Sánchez Karen, and Taboada Barajas Jesús. "Uncinate Fasciculus in Temporal Lobe Epilepsy." Brain and Neurological Disorders 2, no. 2 (2019): 01–04. http://dx.doi.org/10.31579/2642-973x/010.

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Background and purpose: Temporal lobe epilepsy is the most common focal intractable epilepsy. Uncinate fasciculus is a white fiber bundle that connects the orbitofrontal cortex with the anterior temporal lobe, and is implicated in most of the superior mental functions. There is evidence of uncinate fasciculus as a propagation pathway of seizures from temporal lobe. The aim of the study is to determine uncinate fasciculus alterations in patients with temporal lobe epilepsy, through fractional anisotropy. Methods: Thirty-three patients with temporal lobe epilepsy (10 right and 23 left) were stud

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Blume, Warren T. "Hyperventilation, More than Just Hot Air." Epilepsy Currents 6, no. 3 (2006): 76–77. http://dx.doi.org/10.1111/j.1535-7511.2006.00103.x.

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Hyperventilation Revisited: Physiological Effects and Efficacy on Focal Seizure Activation in the Era of Video-EEG Monitoring Guaranha MS, Garzon E, Buchpiguel CA, Tazima S, Yacubian EM, Sakamoto AC Epilepsia 2005;46(1):69–75 Purpose Hyperventilation is an activation method that provokes physiological slowing of brain rhythms, interictal discharges, and seizures, especially in generalized idiopathic epilepsies. In this study, we assessed its effectiveness in inducing focal seizures during video-EEG monitoring. Methods We analyzed the effects of hyperventilation (HV) during video-EEG monitoring

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Sundram, Frederick, Mary Cannon, Colin P. Doherty, et al. "Neuroanatomical correlates of psychosis in temporal lobe epilepsy: voxel-based morphometry study." British Journal of Psychiatry 197, no. 6 (2010): 482–92. http://dx.doi.org/10.1192/bjp.bp.110.080218.

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BackgroundTemporal lobe epilepsy is associated with a significant risk of psychosis but there are only limited studies investigating the underlying neurobiology.AimsTo characterise neuroanatomical changes in temporal lobe epilepsy and comorbid psychosis.MethodThe study population comprised all individuals with temporal lobe epilepsy on the epilepsy database at the National Centre for Epilepsy and Epilepsy Neurosurgery in Ireland (Beaumont Hospital) between 2002 and 2006. Ten people with temporal lobe epilepsy with psychosis were matched for age, gender, handedness, epilepsy duration, seizure l

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Pardo-Peña, Kenia, Salvador M. Martínez-Gallegos, and Marco A. Noriega-Ruiz. "Efecto de los antioxidantes en la epilepsia del lóbulo temporal." e-CUCBA 9, no. 18 (2022): 177–91. http://dx.doi.org/10.32870/ecucba.vi18.252.

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Epilepsy is a common neurological disorder that affects around 70 million people in the world, which represents approximately 1%of the world population. Seizures are transitory episodes produced by excessive neuronal discharges. They are characterized bytransient behavioral changes that are caused by abnormal and excessive neuronal synchronization in the brain. These episodes canbe triggered by genetic or acquired factors that alter normal brain function such as autoimmune diseases, genetic mutations,encephalopathies, head trauma, cerebrovascular accidents, febrile seizures or statusepilepticu

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Machegger, Lukas, Pilar Bosque Varela, Bernardo Crespo Pimentel, and Giorgi Kuchukhidze. "Connectomes in Temporal Lobe and Idiopathic Generalized Epilepsies." Journal of Clinical Medicine 14, no. 11 (2025): 3744. https://doi.org/10.3390/jcm14113744.

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Epilepsy is widely known as a network disease. Ictal and interictal activities are generated and spread within the existing networks involving different regions of the brain. Network alterations affect both grey and white matter, deep brain nuclei, including those of the ascending reticular formation. These structures may be involved in a disorganized connectome associated with epilepsy. A growing body of neuroimaging and neuropsychological findings suggests that global and focal network aberrations are closely linked to cognitive deficits in epilepsy patients. This evidence relates equally to

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Halász, Péter. "The medial temporal lobe epilepsy is a bilateral disease – novel aspects." Journal of Epileptology 24, no. 2 (2016): 141–55. http://dx.doi.org/10.1515/joepi-2016-0010.

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SummaryIntroduction.Medial temporal lobe epilepsy (MTLE) is the most frequent form of epilepsy in adulthood. It is classified as local/regional epilepsy. However, there is increasing evidence of the involvement of both temporal lobes and this provides abundant arguments to question this view, and consider MTLE as one of the typical bilateral system epilepsies.Aim.To provide a contemporary review of medial temporal lobe epilepsy, discussing the bilateral aspects, with reference to epilepsy surgery.Methods.A literature review and a resume of the author’s own experiences with MTLE patients.Result

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Devinsky, Orrin. "Is Behavior in Temporal Lobe Epilepsy Different than in Other Epilepsies? the Jury is Out." Epilepsy Currents 7, no. 4 (2007): 95–96. http://dx.doi.org/10.1111/j.1535-7511.2007.00184.x.

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Interictal Depression, Anxiety, Personality Traits, and Psychological Dissociation in Patients with Temporal Lobe Epilepsy (TLE) and Extra-TLE. Swinkels WA, van Emde Boas W, Kuyk J, van Dyck R, Spinhoven P. Epilepsia 2006;47(12):2092–2103. PURPOSE: This study was performed to investigate the relation between symptoms of interictal depression, anxiety, personality traits, and psychological dissociation with the localization and lateralization of the epileptogenic zone in patients with partial epilepsy. METHODS: All patients were diagnosed according to the localization-related concept of the 198

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Chandanala, Shashank, Harishchandra Prasad YS, Chiatra Venugopal, and Anandh Dhanushkodi. "Stem Cells Based Therapy for Temporal Lobe Epilepsy." JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES 04, no. 2 (2014): 267–71. http://dx.doi.org/10.58739/jcbs/v04i2.12.

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Ferreira, Fabio Thadeu, Eliane Kobayashi, Iscia Lopes-Cendes, and Fernando Cendes. "Structural Abnormalities are Similar in Familial and Nonfamilial Mesial Temporal Lobe Epilepsy." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 31, no. 3 (2004): 368–72. http://dx.doi.org/10.1017/s0317167100003462.

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Background/Objective:Diffuse temporal lobe abnormalities can be observed on MRI of patients with mesial temporal lobe epilepsy (MTLE). Our objective was to perform qualitative and quantitative analyses of temporal lobe structures in patients with familial MTLE (FMTLE) and nonfamilial MTLE.Methods:Two groups of patients were ascertained: 67 FMTLE patients (14 with refractory seizures) and 30 patients with nonfamilial refractory MTLE. We performed qualitative analyses of MRI (with multiplanar reconstruction) and volumes of hippocampi and anterior temporal lobes in all patients, and in a normal c

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Brasil de Carvalho, Maria Isabel, Arthur Rodrigues Souza de Lima, Caroline Isabele Cavalcanti de Araújo, et al. "Eficácia da cirurgia na epilepsia do lobo temporal com esclerose hipocampal." Revista Neurociências 33 (February 19, 2025): 1–18. https://doi.org/10.34024/rnc.2025.v33.19564.

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Introdução. A epilepsia do lobo temporal com esclerose hipocampal é uma das formas mais comuns e desafiadoras de epilepsia, frequentemente acompanhada de convulsões recorrentes e impactos na qualidade de vida. O tratamento cirúrgico convencional apresenta bons resultados no controle das crises, enquanto novas abordagens minimamente invasivas estão sendo desenvolvidas com o objetivo de melhorar ainda mais o prognóstico. Objetivo. Evidenciar a eficácia do tratamento cirúrgico e abordar novas técnicas terapêuticas para pacientes com epilepsia do lobo temporal com esclerose hipocampal. Método. As

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Larivière, Sara, Raúl Rodríguez-Cruces, Jessica Royer, et al. "Network-based atrophy modeling in the common epilepsies: A worldwide ENIGMA study." Science Advances 6, no. 47 (2020): eabc6457. http://dx.doi.org/10.1126/sciadv.abc6457.

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Epilepsy is increasingly conceptualized as a network disorder. In this cross-sectional mega-analysis, we integrated neuroimaging and connectome analysis to identify network associations with atrophy patterns in 1021 adults with epilepsy compared to 1564 healthy controls from 19 international sites. In temporal lobe epilepsy, areas of atrophy colocalized with highly interconnected cortical hub regions, whereas idiopathic generalized epilepsy showed preferential subcortical hub involvement. These morphological abnormalities were anchored to the connectivity profiles of distinct disease epicenter

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Tedrus, Glória Maria de Almeida Souza, and Lineu Corrêa Fonseca. "Epilepsia e espiritualidade/religiosidade." Revista de Ciências Médicas 19, no. 1/6 (2012): 81. http://dx.doi.org/10.24220/2318-0897v19n1/6a832.

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As implicações da espiritualidade/religiosidade na saúde vêm sendo estudadas e documentadas cientificamente. A relação entre epilepsia e espiritualidade/religiosidade está presente na história da humanidade e também tem sido alvo de investigação em décadas recentes. Este estudo utilizou as bases de dados e Lilacs e MedLine, a partir da busca com os descritores spirituality AND epilepsy, e com religious AND epilepsy, nos idiomas inglês, espanhol e português, em artigos publicados no período de 1997 a 2009. São apresentados nesta revisão, de forma sistemática, os achados dos estudos, distribuído

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Hermann, Bruce, and Michael Seidenberg. "Neuropsychology and Temporal Lobe Epilepsy." CNS Spectrums 7, no. 5 (2002): 343–48. http://dx.doi.org/10.1017/s1092852900017806.

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ABSTRACTThe purpose of this article is to review aspects of the neuropsychology of temporal lobe epilepsy. Evidence will be presented to demonstrate that the cognitive consequences of this focal seizure disorder can be more generalized in nature than expected. Consistent with the extratemporal neurocognitive findings, careful quantitative magnetic resonance imaging volumetrics have shown that structural brain changes may be detected outside the temporal lobes. Many factors can potentially affect cognition and brain structure. We focus on the potential neurodevelopmental impact of early-onset t

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Téllez-Zenteno, Jose F., and Lizbeth Hernández-Ronquillo. "A Review of the Epidemiology of Temporal Lobe Epilepsy." Epilepsy Research and Treatment 2012 (December 29, 2012): 1–5. http://dx.doi.org/10.1155/2012/630853.

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Partial-onset epilepsies account for about 60% of all adult epilepsy cases, and temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for epilepsy surgery and often refractory to antiepileptic drugs (AEDs). Little is known about the epidemiology of TLE, because it requires advanced neuroimaging, positive EEG, and appropriate clinical semiology to confirm the diagnosis. Moreover, recently recognized incidentally detected mesial temporal sclerosis in otherwise healthy individuals and benign temporal epilepsy indicate that the true epidemiology of TLE is underestimated

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Onat, Filiz Yılmaz, and Esat Eşkazan. "Are Absence and Limbic Seizures Mutually Exclusive?: An Experimental Approach to Enigmatic Clinical Concept." Journal of Pediatric Epilepsy 10, no. 02 (2021): 045–50. http://dx.doi.org/10.1055/s-0041-1722870.

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AbstractThe impressive advances in the several disciplines including neurophysiology, molecular biology, neuroimmunology, neurogenetics, neuroimaging, and neuropharmacology of epilepsies have been stimulating a mutual interaction among basic scientists, clinicians, and professionals from other disciplines, leading to the identification of clinical questions and then the design of basic science paradigms to test enigmatic clinical issues. Based on a clinical observation that the coexistence of genetic (idiopathic) generalized typical absence and mesial temporal lobe epilepsy in the same patient

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Madan, Ehsaas. "Cognitive Impairment in Patients with Left Temporal Lobe Epilepsy." International Journal of Science and Research (IJSR) 11, no. 5 (2022): 1467–71. http://dx.doi.org/10.21275/sr22519134108.

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Narodova, E. A., N. A. Shnayder, V. V. Narodova, E. E. Erahtin, and D. V. Dmitrenko. "The effect of anxiety on the parameters of carpal tapping in patients with post-stroke epilepsy." Epilepsy and paroxysmal conditions 12, no. 1 (2020): 26–35. http://dx.doi.org/10.17749/2077-8333.2020.12.1.26-35.

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Aim. To study the characteristics of carpal tapping in the normal condition and the effect of subclinical anxiety on its parameters with post-stroke epilepsy in adults.Material and methods. We examined 140 people aged from 22 to 55 years. The total sample was divided into 3 observation groups: the first (I) group included healthy volunteers; the second (II) group included the patients with post-stroke frontal lobe epilepsy; the third (III) group included the patients with post-stroke temporal lobe epilepsy. Each group was divided into two subgroups: subgroup Ia (33 people) included healthy vol

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Engel, Jerome. "When is temporal lobe epilepsy not temporal lobe epilepsy?" Brain 139, no. 2 (2016): 309–12. http://dx.doi.org/10.1093/brain/awv374.

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Lu, Yang, Tao Xue, Jie Yuan та ін. "Increased expression of TGFβ type I receptor in brain tissues of patients with temporal lobe epilepsy". Clinical Science 117, № 1 (2009): 17–22. http://dx.doi.org/10.1042/cs20080347.

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TβRs (transforming growth factor β receptors) have recently been identified in animal experiments as being involved in the pathogenesis of epilepsy. The aim of the present study was to understand further the potential effects of TβRs in human epilepsy. Tissue samples of temporal neocortices from 30 patients with temporal lobe epilepsy were prepared for detecting TβR-I (type 1 TβR) protein expression using immunohistochemistry, immunofluorescence and Western blotting. We compared these tissues with histologically normal temporal lobes from controls. TβR-I immunoreactivity was increased in the p

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Mellers, John D. C., Naoto Adachi, Noriyoshi Takei, Alice Cluckie, Brian K. Toone, and W. Alwyn Lishman. "SPET study of verbal fluency in schizophrenia and epilepsy." British Journal of Psychiatry 173, no. 1 (1998): 69–74. http://dx.doi.org/10.1192/bjp.173.1.69.

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BackgroundThe association between temporal lobe epilepsy and schizophrenia suggests that the critical abnormality may be pathology within the temporal lobes. People with schizophrenia-like psychosis of epilepsy (SLPE) provide a useful group in which to examine the importance of temporal and frontal lobe dysfunction in schizophrenia.MethodA verbal fluency activation paradigm and a 99mTc HMPAO SPET were used to study frontotemporal function in people with SLPE (n = 12), schizophrenia (n = 11) and epilepsy (n = 16).ResultsPeople with SLPE differed from both other groups by showing lower blood flo

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Javidan, Manouchehr. "Electroencephalography in Mesial Temporal Lobe Epilepsy: A Review." Epilepsy Research and Treatment 2012 (June 17, 2012): 1–17. http://dx.doi.org/10.1155/2012/637430.

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Electroencephalography (EEG) has an important role in the diagnosis and classification of epilepsy. It can provide information for predicting the response to antiseizure drugs and to identify the surgically remediable epilepsies. In temporal lobe epilepsy (TLE) seizures could originate in the medial or lateral neocortical temporal region, and many of these patients are refractory to medical treatment. However, majority of patients have had excellent results after surgery and this often relies on the EEG and magnetic resonance imaging (MRI) data in presurgical evaluation. If the scalp EEG data

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Mórocz, I. Á., A. Karni, S. Haut, G. Lantos, and G. Liu. "fMRI of triggerable aurae in musicogenic epilepsy." Neurology 60, no. 4 (2003): 705–9. http://dx.doi.org/10.1212/01.wnl.0000047346.96206.a9.

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The authors studied a patient with musicogenic epilepsy triggered by one specific musical piece using 3D PRESTO fMRI. During epileptic aurae initiated by the stimulus, signal increases were found in the left anterior temporal lobe, correlating with ictal EEG and SPECT showing a left anterior temporal focus, and the right gyrus rectus. Because fMRI indicated a cascade of recruitment of the ventral frontal lobes by epileptogenic music, left anterior temporal lobe activity could be secondary to a right gyrus rectus focus, possibly triggered by emotional processing of music.

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Carne, Ross P., Terence J. O'Brien, Christine J. Kilpatrick, et al. "Temporal Lobe Epilepsy." Journal of Neurosurgery 103, no. 4 (2005): 768–69. http://dx.doi.org/10.3171/jns.2005.103.4.0768.

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Abstract Object. The syndrome of medial temporal lobe epilepsy (MTLE) may occur in patients in whom magnetic resonance (MR) images demonstrate normal findings. In these patients, there is no evidence of hippocampal sclerosis on neuroimaging, and histopathological examination of the resected hippocampus does not reveal significant neuron loss. In this paper the authors describe the distinct clinical features of this MTLE subtype, referred to as paradoxical temporal lobe epilepsy (PTLE). Methods. The authors selected 12 consecutive patients with preoperative findings consistent with MTLE in whom

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Beit-Jones, Meredith S., and Lissa Robins Kapust. "Temporal Lobe Epilepsy." Social Work in Health Care 11, no. 2 (1986): 17–33. http://dx.doi.org/10.1300/j010v11n02_02.

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Bernhardt, Boris C., Fatemeh Fadaie, Min Liu, et al. "Temporal lobe epilepsy." Neurology 92, no. 19 (2019): e2209-e2220. http://dx.doi.org/10.1212/wnl.0000000000007447.

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ObjectiveTo assess whether hippocampal sclerosis (HS) severity is mirrored at the level of large-scale networks.MethodsWe studied preoperative high-resolution anatomical and diffusion-weighted MRI of 44 temporal lobe epilepsy (TLE) patients with histopathologic diagnosis of HS (n = 25; TLE-HS) and isolated gliosis (n = 19; TLE-G) and 25 healthy controls. Hippocampal measurements included surface-based subfield mapping of atrophy and T2 hyperintensity indexing cell loss and gliosis, respectively. Whole-brain connectomes were generated via diffusion tractography and examined using graph theory a

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Garyfallos, George, Nikolas Manos, and Aravela Adamopoulou. "Temporal Lobe Epilepsy." British Journal of Psychiatry 153, no. 6 (1988): 852–53. http://dx.doi.org/10.1192/bjp.153.6.852.

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Hatton, Sean N., Khoa H. Huynh, Leonardo Bonilha, et al. "White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA-Epilepsy study." Brain 143, no. 8 (2020): 2454–73. http://dx.doi.org/10.1093/brain/awaa200.

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Abstract The epilepsies are commonly accompanied by widespread abnormalities in cerebral white matter. ENIGMA-Epilepsy is a large quantitative brain imaging consortium, aggregating data to investigate patterns of neuroimaging abnormalities in common epilepsy syndromes, including temporal lobe epilepsy, extratemporal epilepsy, and genetic generalized epilepsy. Our goal was to rank the most robust white matter microstructural differences across and within syndromes in a multicentre sample of adult epilepsy patients. Diffusion-weighted MRI data were analysed from 1069 healthy controls and 1249 pa

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Arita, Kazunori, Koshi Yokota, Yushi Nagano, et al. "Classical type of superficial hemosiderosis presenting with temporal lobe epilepsy." Surgical Neurology International 16 (June 6, 2025): 225. https://doi.org/10.25259/sni_153_2025.

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Background: Classical type of superficial hemosiderosis (SH) is subpial hemosiderin deposition mainly affecting the cerebellum, brainstem, and spinal cord, which generally presents with cerebellar ataxia and sensorineural hearing disturbance. We here report a rare case of the classical type of SH presenting with temporal lobe epilepsy and perform a literature review on similar cases. Case Description: A 63-year-old man with four episodes of impaired awareness and confusion lasting for around 5 minutes after feeling vague uneasiness, suggesting focal impaired awareness seizure, visited a neuros

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Barba, Carmen, Sylvain Rheims, Lorella Minotti, et al. "Temporal plus epilepsy is a major determinant of temporal lobe surgery failures." Brain 139, no. 2 (2015): 444–51. http://dx.doi.org/10.1093/brain/awv372.

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Abstract See Engel (doi:10.1093/awv374) for a scientific commentary on this article. Reasons for failed temporal lobe epilepsy surgery remain unclear. Temporal plus epilepsy, characterized by a primary temporal lobe epileptogenic zone extending to neighboured regions, might account for a yet unknown proportion of these failures. In this study all patients from two epilepsy surgery programmes who fulfilled the following criteria were included: (i) operated from an anterior temporal lobectomy or disconnection between January 1990 and December 2001; (ii) magnetic resonance imaging normal or showi

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Allebone, James, Richard Kanaan, and Sarah J. Wilson. "Systematic review of structural and functional brain alterations in psychosis of epilepsy." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 6 (2017): 611–17. http://dx.doi.org/10.1136/jnnp-2017-317102.

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This systematic review critically assesses structural and functional neuroimaging studies of psychosis of epilepsy (POE). We integrate findings from 18 studies of adults with POE to examine the prevailing view that there is a specific relationship between temporal lobe epilepsy (TLE) and POE, and that mesial temporal lobe pathology is a biomarker for POE. Our results show: (1) conflicting evidence of volumetric change in the hippocampus and amygdala; (2) distributed structural pathology beyond the mesial temporal lobe; and (3) changes in frontotemporal functional network activation. These resu

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Meguins, Lucas Crociati, Rodrigo Antônio Rocha da Cruz Adry, Sebastião Carlos da Silva Júnior, et al. "Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis." Arquivos de Neuro-Psiquiatria 73, no. 12 (2015): 1014–18. http://dx.doi.org/10.1590/0004-282x20150175.

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ABSTRACT Objective To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-thre

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Fried, Itzhak. "Anatomic Temporal Lobe Resections for Temporal Lobe Epilepsy." Neurosurgery Clinics of North America 4, no. 2 (1993): 233–42. http://dx.doi.org/10.1016/s1042-3680(18)30590-4.

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Blair, Robert D. G. "Temporal Lobe Epilepsy Semiology." Epilepsy Research and Treatment 2012 (March 7, 2012): 1–10. http://dx.doi.org/10.1155/2012/751510.

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Epilepsy represents a multifaceted group of disorders divided into two broad categories, partial and generalized, based on the seizure onset zone. The identification of the neuroanatomic site of seizure onset depends on delineation of seizure semiology by a careful history together with video-EEG, and a variety of neuroimaging technologies such as MRI, fMRI, FDG-PET, MEG, or invasive intracranial EEG recording. Temporal lobe epilepsy (TLE) is the commonest form of focal epilepsy and represents almost 2/3 of cases of intractable epilepsy managed surgically. A history of febrile seizures (especi

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Avanzini, Giuliano. "Do Seizures Promote Epileptogenesis and Cause Cognitive Decline?" European Neurological Review 9, no. 2 (2015): 120. http://dx.doi.org/10.17925/enr.2014.09.02.120.

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The assumption that repeated seizures may induce a progression of epilepsies towards an intractable condition and a cognitive decline does not hold true for idiopathic epilepsies but can only be considered for mesial temporal lobe epilepsy and epileptic encephalopathies. The available evidence leads to the conclusion that in most cases the epilepsy worsening and cognitive decline are due to the progression of the underlying pathology or to its interference with the developmental programme, the notable exception being the epileptic encephalopathies with continuous epileptic activity during slee

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Caboclo, Luís Otávio Sales Ferreira, Rafael Scarpa Neves, Anaclara Prada Jardim, et al. "Surgical and postmortem pathology studies: contribution for the investigation of temporal lobe epilepsy." Arquivos de Neuro-Psiquiatria 70, no. 12 (2012): 945–52. http://dx.doi.org/10.1590/s0004-282x2012001200009.

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Pathology studies in epilepsy patients bring useful information for comprehending the physiopathology of various forms of epilepsy, as well as aspects related to response to treatment and long-term prognosis. These studies are usually restricted to surgical specimens obtained from patients with refractory focal epilepsies. Therefore, most of them pertain to temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) and malformations of cortical development (MCD), thus providing information of a selected group of patients and restricted regions of the brain. Postmortem whole brain studie

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Mandell, Jason G., Kenneth L. Hill, Dan T. D. Nguyen, et al. "Volumetric brain analysis in neurosurgery: Part 3. Volumetric CT analysis as a predictor of seizure outcome following temporal lobectomy." Journal of Neurosurgery: Pediatrics 15, no. 2 (2015): 133–43. http://dx.doi.org/10.3171/2014.9.peds12428.

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OBJECT The incidence of temporal lobe epilepsy (TLE) due to mesial temporal sclerosis (MTS) can be high in developing countries. Current diagnosis of MTS relies on structural MRI, which is generally unavailable in developing world settings. Given widespread effects on temporal lobe structure beyond hippocampal atrophy in TLE, the authors propose that CT volumetric analysis can be used in patient selection to help predict outcomes following resection. METHODS Ten pediatric patients received preoperative CT scans and temporal resections at the CURE Children's Hospital of Uganda. Engel classifica

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Cascino, Gregory D. "Temporal Lobe Epilepsy: More than Hippocampal Pathology." Epilepsy Currents 5, no. 5 (2005): 187–89. http://dx.doi.org/10.1111/j.1535-7511.2005.00059.x.

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Voxel-based Morphometry of the Thalamus in Patients with Refractory Medial Temporal Lobe Epilepsy Bonilha L, Rorden C, Castellano G, Cendes F, Li LM Neuroimage 2005;25:1016–1021 Previous research has suggested that patients with refractory medial temporal lobe epilepsy (MTLE) show gray matter atrophy both within the temporal lobes and in the thalamus. However, these studies have not distinguished between different nuclei within the thalamus. We examined whether thalamic atrophy correlates with the nuclei's connections to other regions in the limbic system. T1-weighted MRI scans were obtained f

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Lassonde, Maryse, Hannelore C. Sauerwein, Isabelle Jambaqué, Mary Lou Smith, and Christoph Helmstaedter. "Neuropsychology of childhood epilepsy: Pre‐ and postsurgical assessment." Epileptic Disorders 2, no. 1 (2000): 3–13. http://dx.doi.org/10.1684/j.1950-6945.2000.tb00342.x.

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ABSTRACT Childhood epilepsy is one of the most prevalent forms of chronic and disabling childhood disorders. Because it disrupts brain maturation, it has long been thought to produce non‐specific consequences such as mental deficiency and behavioral problems. However, advances in medical knowledge have shown that childhood epilepsy should not be considered as a single disorder, and it is now becoming apparent that various clinical entities have different cognitive expressions that yet need to be specified. The purpose of this paper is to provide an up‐to‐date analysis of this multi‐faceted pat

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Régis, Jean, Fabrice Bartolomei, M. Rey, Motohiro Hayashi, Patrick Chauvel, and Jean-Claude Peragut. "Gamma knife surgery for mesial temporal lobe epilepsy." Journal of Neurosurgery 93, supplement_3 (2000): 141–46. http://dx.doi.org/10.3171/jns.2000.93.supplement_3.0141.

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Object. Gamma knife radiosurgery (GKS) allows precise and complete destruction of chosen target structures containing healthy and/or pathological cells, without causing significant radiation damage to adjacent tissues. Almost all the well-documented cases of radiosurgery for epilepsy are for epilepsies associated with space-occupying lesions. These results prompted the authors to investigate the use of radiosurgery as a new way of treating epilepsy not associated with space-occupying lesions. Methods. To evaluate this new method, 25 patients who presented with drug-resistant mesial temporal lo

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Cascino, Gregory D. "Widespread Neuronal Dysfunction in Temporal Lobe Epilepsy." Epilepsy Currents 3, no. 1 (2003): 31–32. http://dx.doi.org/10.1111/j.1535-7597.2003.03113.x.

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Reduced Extrahippocampal NAA in Mesial Temporal Lobe Epilepsy Mueller SG, Suhy J, Laxer KD, Flenniken DL, Axelrad J, Capizzano AA, Weiner MW Epilepsia 2002;43(10):1210–1216 Purpose Structural and metabolic abnormalities in the hippocampal region in medial temporal lobe epilepsy (mTLE) are well described; less is known about extrahippocampal changes. This study was designed to characterize extrahippocampal metabolic abnormalities in mTLE with magnetic resonance spectroscopy in combination with tissue segmentation and volumetry of gray and white matter. Methods Multislice magnetic resonance spec

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Bercovici, Eduard, Balagobal Santosh Kumar, and Seyed M. Mirsattari. "Neocortical Temporal Lobe Epilepsy." Epilepsy Research and Treatment 2012 (July 16, 2012): 1–15. http://dx.doi.org/10.1155/2012/103160.

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Complex partial seizures (CPSs) can present with various semiologies, while mesial temporal lobe epilepsy (mTLE) is a well-recognized cause of CPS, neocortical temporal lobe epilepsy (nTLE) albeit being less common is increasingly recognized as separate disease entity. Differentiating the two remains a challenge for epileptologists as many symptoms overlap due to reciprocal connections between the neocortical and the mesial temporal regions. Various studies have attempted to correctly localize the seizure focus in nTLE as patients with this disorder may benefit from surgery. While earlier work

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Sato, Mitsumoto, and Matsue Miyasaka. "Symposium: Temporal Lobe Epilepsy." Psychiatry and Clinical Neurosciences 48, no. 2 (1994): 203–4. http://dx.doi.org/10.1111/j.1440-1819.1994.tb03051.x.

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Benbadis, S. R., W. A. Gerson, J. H. Harvey, and H. O. Luders. "Photosensitive temporal lobe epilepsy." Neurology 46, no. 6 (1996): 1540–42. http://dx.doi.org/10.1212/wnl.46.6.1540.

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Bernasconi, A., F. Andermann, F. Cendes, F. Dubeau, E. Andermann, and A. Olivier. "Nocturnal temporal lobe epilepsy." Neurology 50, no. 6 (1998): 1772–77. http://dx.doi.org/10.1212/wnl.50.6.1772.

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