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1

André, Sonia, Zahid Raja, Vincent Humblot, et al. "Functional Characterization of Temporin-SHe, a New Broad-Spectrum Antibacterial and Leishmanicidal Temporin-SH Paralog from the Sahara Frog (Pelophylax saharicus)." International Journal of Molecular Sciences 21, no. 18 (2020): 6713. http://dx.doi.org/10.3390/ijms21186713.

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Amphibian skin is a promising natural resource for antimicrobial peptides (AMPs), key effectors of innate immunity with attractive therapeutic potential to fight antibiotic-resistant pathogens. Our previous studies showed that the skin of the Sahara Frog (Pelophylax saharicus) contains broad-spectrum AMPs of the temporin family, named temporins-SH. Here, we focused our study on temporin-SHe, a temporin-SHd paralog that we have previously identified in this frog but was never structurally and functionally characterized. We synthesized and determined the structure of temporin-SHe. This non-amphi
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2

RINALDI, Andrea C., Maria Luisa MANGONI, Anna RUFO, et al. "Temporin L: antimicrobial, haemolytic and cytotoxic activities, and effects on membrane permeabilization in lipid vesicles." Biochemical Journal 368, no. 1 (2002): 91–100. http://dx.doi.org/10.1042/bj20020806.

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The temporins are a family of small, linear antibiotic peptides with intriguing biological properties. We investigated the antibacterial, haemolytic and cytotoxic activities of temporin L (FVQWFSKFLGRIL-NH2), isolated from the skin of the European red frog Rana temporaria. The peptide displayed the highest activity of temporins studied to date, against both human erythrocytes and bacterial and fungal strains. At variance with other known temporins, which are mainly active against Gram-positive bacteria, temporin L was also active against Gram-negative strains such as Pseudomonas aeruginosa A.T
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3

Rollins-Smith, Louise A., Cynthia Carey, J. Michael Conlon, et al. "Activities of Temporin Family Peptides against the Chytrid Fungus (Batrachochytrium dendrobatidis) Associated with Global Amphibian Declines." Antimicrobial Agents and Chemotherapy 47, no. 3 (2003): 1157–60. http://dx.doi.org/10.1128/aac.47.3.1157-1160.2003.

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ABSTRACT Temporin A and structurally related peptides produced in amphibian dermal granular glands and in wasp venom were tested for growth inhibition of Batrachochytrium dendrobatidis, a pathogen associated with global amphibian declines. Two natural amphibian temporins, a wasp temporin, and six synthetic analogs effectively inhibited growth. Differences in potency due to amino acid substitution suggest that ability to penetrate membranes and form an α-helical structure is important for their effectiveness against this pathogen.
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4

Roux, Louis. "Veritas Filia Temporis." XVII-XVIII. Revue de la société d'études anglo-américaines des XVIIe et XVIIIe siècles 68, no. 1 (2011): 11–28. http://dx.doi.org/10.3406/xvii.2011.2462.

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5

Rappe, A., M. Görtler, and Z. Halloul. "De ratione temporis." Gefässchirurgie 21, no. 7 (2016): 495–502. http://dx.doi.org/10.1007/s00772-016-0204-0.

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6

Uccelletti, Daniela, Elena Zanni, Ludovica Marcellini, Claudio Palleschi, Donatella Barra, and Maria Luisa Mangoni. "Anti-Pseudomonas Activity of Frog Skin Antimicrobial Peptides in a Caenorhabditis elegans Infection Model: a Plausible Mode of Action In Vitro and In Vivo." Antimicrobial Agents and Chemotherapy 54, no. 9 (2010): 3853–60. http://dx.doi.org/10.1128/aac.00154-10.

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ABSTRACT The emergence of multidrug-resistant (MDR) microorganisms makes it increasingly difficult to treat infections. These infections include those associated with Pseudomonas aeruginosa, which are hard to eradicate, especially in patients with a compromised immune system. Naturally occurring membrane-active cationic antimicrobial peptides (CAMPs) serve as attractive candidates for the development of new therapeutic agents. Amphibian skin is one of the richest sources for such peptides, but only a few studies on their in vivo activities and modes of action have been reported. We investigate
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7

Altisen, Karine, Pierre-Alain Markey, Nicolas Reynier, and Stavros Tripakis. "Implémentabilité des automates temporisés." Journal Européen des Systèmes Automatisés 39, no. 1-3 (2005): 395–406. http://dx.doi.org/10.3166/jesa.39.395-406.

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8

Roy, Maëva, Lucie Lebeau, Céline Chessa, et al. "Comparison of Anti-Viral Activity of Frog Skin Anti-Microbial Peptides Temporin-Sha and [K3]SHa to LL-37 and Temporin-Tb against Herpes Simplex Virus Type 1." Viruses 11, no. 1 (2019): 77. http://dx.doi.org/10.3390/v11010077.

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Temporins are anti-microbial peptides synthesized in the skin of frogs of the Ranidae family. The few studies to date that have examined their anti-viral properties have shown that they have potential as anti-viral therapies. In this work, we evaluated the anti-herpes simplex virus type 1 (HSV-1) activity of the temporin-SHa (SHa) and its synthetic analog [K3]SHa. Human cathelicidin LL-37 and temporin-Tb (Tb), previously demonstrated to have anti-HSV-1 properties, were used as positive controls. We observed that SHa and [K3]SHa significantly inhibit HSV-1 replication in human primary keratinoc
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9

Bhunia, Anirban, Rathi Saravanan, Harini Mohanram, Maria L. Mangoni, and Surajit Bhattacharjya. "NMR Structures and Interactions of Temporin-1Tl and Temporin-1Tb with Lipopolysaccharide Micelles." Journal of Biological Chemistry 286, no. 27 (2011): 24394–406. http://dx.doi.org/10.1074/jbc.m110.189662.

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Temporins are a group of closely related short antimicrobial peptides from frog skin. Lipopolysaccharide (LPS), the major constituent of the outer membrane of Gram-negative bacteria, plays important roles in the activity of temporins. Earlier studies have found that LPS induces oligomerization of temporin-1Tb (TB) thus preventing its translocation across the outer membrane and, as a result, reduces its activity on Gram-negative bacteria. On the other hand, temporin-1Tl (TL) exhibits higher activity, presumably because of lack of such oligomerization. A synergistic mechanism was proposed, invol
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10

Chaves P. Carvalho, Aldenora M. "(A)temporais." Revista Letras Raras 10, no. 1 (2021): 267. http://dx.doi.org/10.35572/rlr.v10i1.2053.

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11

Gorshkova, V. V. "TEMPORIS CAUSA: THE DEVELOPMENT OF THE MUSEUM COLLECTION OF ICONS IN YAROSLAVL: 1922–1930." Kunstkamera 8, no. 2 (2020): 42–52. http://dx.doi.org/10.31250/2618-8619-2020-2(8)-42-52.

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12

Bouyer, Patricia, Fabrice Chevalier, Moez Krichen, and Stavros Tripakis. "Observation partielle des systèmes temporisés." Journal Européen des Systèmes Automatisés 39, no. 1-3 (2005): 381–93. http://dx.doi.org/10.3166/jesa.39.381-393.

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13

Guerrero, Rafael Ramón. "Veritas filia temporis en Averroes." Tópicos, Revista de Filosofía 29, no. 1 (2013): 13. http://dx.doi.org/10.21555/top.v29i1.210.

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Averroes, fuertemente influenciado por Aristóteles, afirmó la necesidad de la experiencia para incrementar todo conocimiento. La verdad, la última naturaleza de las cosas, se obtiene conforme transcurre el tiempo y sólo es alcanzable aceptando la participación de los predecesores. El progreso implica tradición y mejora: aquélla al impulsar el desarrollo tanto de la cultura como del intelecto, ésta como resultado de la proyección crítica de diversas opiniones, ya que facilita el conocimiento de la verdad y el reconocimiento del error. El progreso científico se alcanza como consecuencia del esfu
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14

Bockholdt, Rudolf. "Semibrevis minima und Prolatio temporis." Die Musikforschung 16, no. 1 (2021): 3–21. http://dx.doi.org/10.52412/mf.1963.h1.2366.

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15

Cohen, Elizabeth F. "Reconsidering US Immigration Reform: The Temporal Principle of Citizenship." Perspectives on Politics 9, no. 3 (2011): 575–83. http://dx.doi.org/10.1017/s1537592711002787.

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The uncertain political status of America's millions of undocumented immigrants and their children has exposed deep and ongoing disagreement about how US citizenship should be accorded to foreign-born persons. I identify the principle ofjus temporis,a law of measured calendrical time, that has worked in concert withjus soliand consent to construct citizenship law since the nation's founding.Jus temporistranslates measured durations of time such as “time in residence” or “time worked” into entitlement to rights and status. It creates temporal algorithms in which measured calendrical time plus a
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16

GRIFFITH, MARK. "BEOWULF 1495: HWIL DÆGES = MOMENTUM TEMPORIS?" Notes and Queries 41, no. 2 (1994): 144–46. http://dx.doi.org/10.1093/nq/41-2-144.

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17

Di Somma, Angela, Carolina Canè, Antonio Moretta, and Angela Duilio. "Interaction of Temporin-L Analogues with the E. coli FtsZ Protein." Antibiotics 10, no. 6 (2021): 704. http://dx.doi.org/10.3390/antibiotics10060704.

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The research of new therapeutic agents to fight bacterial infections has recently focused on the investigation of antimicrobial peptides (AMPs), the most common weapon that all organisms produce to prevent invasion by external pathogens. Among AMPs, the amphibian Temporins constitute a well-known family with high antibacterial properties against Gram-positive and Gram-negative bacteria. In particular, Temporin-L was shown to affect bacterial cell division by inhibiting FtsZ, a tubulin-like protein involved in the crucial step of Z-ring formation at the beginning of the division process. As Fts
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18

Garber, Rogério. "ANÁLISES DE SÉRIES TEMPORAIS." Oecologia Brasiliensis 02, no. 01 (1995): 91–118. http://dx.doi.org/10.4257/oeco.1995.0201.04.

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19

Silva, Cristiany Fernandes da. "Orações-quando temporais-condicionais." Entrepalavras 7, no. 2 (2017): 54. http://dx.doi.org/10.22168/2237-6321.7.7.2.54-73.

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Este artigo discute a polissemia de quando, isto é, as várias acepções que o termo pode assumir, para além da sua denotação canônica de expressar temporalidade, a saber: causalidade, concessividade, condicionalidade, adversatividade e proporcionalidade. Tratamos, especificamente, das orações-quando temporais-condicionais. A partir do conjunto de propriedades que a literatura elenca para a formação dessas sentenças, concluímos, na análise, que há, na verdade, duas restrições operando: uma de leitura (causa-efeito) e uma aspectual (imperfectivo). Argumentamos, por fim, quanto à existência de um
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20

Green, James A. "The ratione temporis elements of self-defence." Journal on the Use of Force and International Law 2, no. 1 (2015): 97–118. http://dx.doi.org/10.1080/20531702.2015.1043097.

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21

Grannes, Alf. "Genitivus temporis in early 18th century Russian." Russian Linguistics 10, no. 1 (1986): 53–60. http://dx.doi.org/10.1007/bf02551593.

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22

Gattini, Andrea. "Jurisdiction ratione temporis in International Investment Arbitration." Law & Practice of International Courts and Tribunals 16, no. 1 (2017): 139–58. http://dx.doi.org/10.1163/15718034-12341345.

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Issues concerning the temporal scope of jurisdiction of international investment arbitration tribunals are attracting increased attention due to recent events, such as the denunciation of the icsid Convention by some states, the denunciation of bilateral investment treaties from which the tribunals draw their jurisdiction, or the provisional application of other treaties concerning investment protection. The solutions offered by most arbitral tribunals are in line with international customary rules on the law of treaties, a point which deserves attention as further proof of the cohesiveness of
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23

TRENTIN, Aline Biasoli, Carline Biasoli TRENTIN, Dejanira Luderitz SALDANHA, and Tatiana Mora KUPLICH. "MODIS TIME SERIES ANALYSIS AND TRMM IN EUCALYPTUS PLANTATIONS." Mercator 17, no. 10 (2018): 1–11. http://dx.doi.org/10.4215/rm2018.e17022.

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24

Komenda, Jan, Sébastien Lahaye, and Jean-Louis Boismond. "Séquentialisation du comportement de réseaux de Petri temporisés." Journal Européen des Systèmes Automatisés 47, no. 1-3 (2013): 139–54. http://dx.doi.org/10.3166/jesa.47.139-154.

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25

Thompson, Dana M., and Michael J. Brenner. "Prescribing Time to Temporize Burnout." JAMA Otolaryngology–Head & Neck Surgery 146, no. 2 (2020): 103. http://dx.doi.org/10.1001/jamaoto.2019.3731.

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26

Oliveira, Thaiane. "Tessituras temporais em jogos pervasivos." Significação: Revista de Cultura Audiovisual 42, no. 43 (2015): 162. http://dx.doi.org/10.11606/issn.2316-7114.sig.2015.97305.

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<p>A proposta deste trabalho é traçar um estudo comparativo entre a temporalidade em dois tipos de jogos pervasivos que exploram a digese, o <em>chronos</em> ordinário da vida cotidiana, o <em>aion</em> do objeto ficcional e imagem dos registros fílmicos destes jogos, a partir das contribuições de Deleuze. Como objeto, iremos analisar alguns registros audiovisuais a fim de refletir sobre a organização temporal da narrativa nos eventos em torno do evento. Buscaremos, com isso, defender que há uma relação estética entre o registro fílmico e a ação do jogo em relação
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27

Luchte, James. "Under the Aspect of Time “Sub Specie Temporis”." Philosophy Today 53, no. 1 (2009): 70–84. http://dx.doi.org/10.5840/philtoday200953168.

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28

Ruszkiewicz, Beata. "‘LONGI TEMPORIS PRAESCRIPTIO’ JAKO ZARZUT DŁUGIEGO OKRESU POSIADANIA." Zeszyty Prawnicze 11, no. 1 (2016): 245. http://dx.doi.org/10.21697/zp.2011.11.1.13.

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‘LONGI TEMPORIS PRAESCRIPTIO’ AS A DEMURRER IN THE MATTER OF LONG POSSESSIONSummary During centuries Praescriptio longi temporis has changed its meaning, requirements, application and nature, therefore, it seems to be adequate, to use it as a subject of the conference entitled “Law at the turn of the century”. This term derives from the Greek law. During the Pre-Classical Age it had its specific nature of an usual procedural privilege, granted on the basis of a long lack of action taken from the opposite party. Since the 1st century AD it had been used in Roman provinces and between peregrines
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29

Zhao, Hongxia, Andrea C. Rinaldi, Antonio Di Giulio, Maurizio Simmaco, and Paavo K. J. Kinnunen. "Interactions of the Antimicrobial Peptides Temporins with Model Biomembranes. Comparison of Temporins B and L†." Biochemistry 41, no. 13 (2002): 4425–36. http://dx.doi.org/10.1021/bi011929e.

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30

Guezzi, Abdelhak, Philippe Decclerck, and Jean-Louis Boimond. "Commande de graphes d'événements temporisés sur un horizon glissant." Journal Européen des Systèmes Automatisés 43, no. 7-9 (2009): 1097–111. http://dx.doi.org/10.3166/jesa.43.1097-1111.

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31

Wade, D., A. Silveira, L. Rollins-Smith, T. Bergman, J. Silberring, and H. Lankinen. "Hematological and antifungal properties of temporin A and a cecropin A-temporin A hybrid." Acta Biochimica Polonica 48, no. 4 (2001): 1185–89. http://dx.doi.org/10.18388/abp.2001_3889.

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Temporin A (TA) and a cecropin A-temporin A hybrid peptide (CATA) were synthesized and assayed for their hemolytic, anticoagulant, and antifungal properties. CATA retains significant antifungal activity, is less hemolytic than TA, and inhibits blood coagulation. These results recommend further studies of the biological activities of CATA.
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32

Šuran, Fulvio. ""Veritas filia temporis" - Povijest, istina, jezik kao tehnološka konstrukcija." Tabula : periodicus Facultatis philosophicae Polensis; rivista della Facoltà di lettere e filosofia; Journal od the Faculty of Humanities No. 9 (2011): 224–37. http://dx.doi.org/10.32728/tab.09.2011.17.

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U uvodnom će se dijelu raspravljati o problematičnosti samog poimanja istine koja, zavisno o povijesnom razdoblju, doživljava određene suštinske promjene - tako je, na primjer, mitska istina bila shvaćena u vidu ritualne efikasnosti, koja se naknadno pod utjecajem retorike i sofistike pretočila u obliku uvjerljivosti (peitho’) kao učinkovitiji kriterij istinitosti od onog mitsko-ritualnog. Nakon uvodnog dijela uvidjet će se kako tek s filozofijom istina poprima današnji oblik logičke učinkovitosti i razumski apstraktne objektivnosti; oblik koji će naknadno dominirati čitavom zapadnom civilizac
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33

Capparelli, Rosanna, Alessandra Romanelli, Marco Iannaccone, et al. "Synergistic Antibacterial and Anti-Inflammatory Activity of Temporin A and Modified Temporin B In Vivo." PLoS ONE 4, no. 9 (2009): e7191. http://dx.doi.org/10.1371/journal.pone.0007191.

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34

D'Abramo, M., A. C. Rinaldi, A. Bozzi, et al. "Conformational behavior of temporin A and temporin L in aqueous solution: A computational/experimental study." Biopolymers 81, no. 3 (2006): 215–24. http://dx.doi.org/10.1002/bip.20404.

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35

Cottenceau, Bertrand, Laurent Hardouin, and Euriell Le Corronc. "Représentation tridimensionnelle de la dynamique des graphes d'événements temporisés généralisés." Journal Européen des Systèmes Automatisés 43, no. 7-9 (2009): 1081–85. http://dx.doi.org/10.3166/jesa.43.1081-1085.

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36

Wade, David, Jerzy Silberring, Rabah Soliymani, et al. "Antibacterial activities of temporin A analogs." FEBS Letters 479, no. 1-2 (2000): 6–9. http://dx.doi.org/10.1016/s0014-5793(00)01754-3.

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37

Wade, David, Jan-Ingmar Flock, Charlotta Edlund, et al. "Antibiotic Properties of Novel Synthetic Temporin A Analogs and a Cecropin A-Temporin A Hybrid Peptide." Protein & Peptide Letters 9, no. 6 (2002): 533–43. http://dx.doi.org/10.2174/0929866023408409.

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38

Sodré, Zuleika Auxiliadora da Luz, and Francisco Carlos Rocha Fernandes. "CARACTERÍSTICAS ESPECTRO-TEMPORAIS DE CORRENTES TIPO I." Revista Univap 19, no. 34 (2013): 76. http://dx.doi.org/10.18066/revunivap.v19i34.245.

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39

Ribeiro, Ana Cláudia Mondini, Renata Coelho Scharlach, and Maria Madalena Canina Pinheiro. "Avaliação dos aspectos temporais em cantores populares." CoDAS 27, no. 6 (2015): 520–25. http://dx.doi.org/10.1590/2317-1782/20152014234.

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RESUMO Objetivo: Avaliar o processamento temporal de cantores populares que tocam ou não instrumento musical. Métodos: O estudo foi composto por 30 cantores populares de bandas baile,15 dos quais cantam e tocam instrumento(s) musical(is) (G1) e 15 apenas cantam (G2). Todos os participantes foram submetidos à realização da avaliação audiológica básica e dos testes do processamento temporal: teste de padrão de frequência (TPF) e teste de detecção de gaps no ruído (GIN). Resultados: Houve diferença estatisticamente significante na comparação do desempenho entre os grupos no que se refere ao limia
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40

Leonardi, Fabrizio, and José Jaime da Cruz. "Projeto de controladores robustos com especificações temporais." Sba: Controle & Automação Sociedade Brasileira de Automatica 16, no. 3 (2005): 279–89. http://dx.doi.org/10.1590/s0103-17592005000300002.

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O projeto de compensadores robustos com especificações no domínio do tempo visando ao acompanhamento do sinal de referência e a rejeição de distúrbios é discutido neste artigo do ponto de vista freqüencial. As condições de projeto são obtidas em função de modelos de referência, os quais contêm as especificações temporais associadas. Mostra-se que quanto maior for a distância entre o modelo nominal da planta e o modelo de referência a ser seguido, mais restritivas serão as condições de projeto. Os problemas podem ser formulados como casos de model matching e o procedimento proposto pode reduzir
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41

Romero, Stella Maris, Alejandra Beatriz Cardillo, María Camila Martínez Ceron, Silvia Andrea Camperi, and Silvana Laura Giudicessi. "Temporins: An Approach of Potential Pharmaceutic Candidates." Surgical Infections 21, no. 4 (2020): 309–22. http://dx.doi.org/10.1089/sur.2019.266.

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42

Mangoni, Maria Luisa, José M. Saugar, Maria Dellisanti, Donatella Barra, Maurizio Simmaco, and Luis Rivas. "Temporins, Small Antimicrobial Peptides with Leishmanicidal Activity." Journal of Biological Chemistry 280, no. 2 (2004): 984–90. http://dx.doi.org/10.1074/jbc.m410795200.

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43

Mangoni, M. L. "Temporins, anti-infective peptides with expanding properties." Cellular and Molecular Life Sciences 63, no. 9 (2006): 1060–69. http://dx.doi.org/10.1007/s00018-005-5536-y.

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44

Beaugrand, Claire. "L’apatridie dans le Golfe : temporiser et marchander." Plein droit 128, no. 1 (2021): 19–22. http://dx.doi.org/10.3917/pld.128.0021.

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45

Dooley, Brendan Maurice. "Veritas Filia Temporis: Experience and Belief in Early Modern Culture." Journal of the History of Ideas 60, no. 3 (1999): 487–504. http://dx.doi.org/10.1353/jhi.1999.0023.

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46

Valkema Blouw, Paul. "Printed in Holland: the anonymous Temporis filia Veritas, [Leiden] 1589." Quaerendo 28, no. 1 (1998): 41–48. http://dx.doi.org/10.1163/157006998x00032.

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47

Przulj, Novo, Dragan Perovic, Milan Mirosavljevic, and Milos Nozinic. "Veritas temporis filia est: Truth is the daughter of time." Selekcija i semenarstvo 22, no. 1 (2016): 53–62. http://dx.doi.org/10.5937/selsem1601053p.

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48

Graup, Susane, Daniele Detanico, Saray Giovana dos Santos, and Antônio Renato Pereira Moro. "Características da marcha de um paciente com osteoartrose de quadril com e sem auxílio de bengala." Fisioterapia e Pesquisa 16, no. 4 (2009): 357–62. http://dx.doi.org/10.1590/s1809-29502009000400013.

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O objetivo deste estudo foi comparar características espaciais, temporais e espaço-temporais da marcha de um paciente com osteoartrose de quadril com e sem o auxílio de dispositivo (bengala). O caso é o de um sujeito com osteoartrose de quadril esquerdo de 63 anos, 97,8 kg e 1,76 m. Um sistema de reconstrução tridimensional de movimento foi utilizado para análise da marcha. Foram registrados três ciclos completos da marcha com e sem a utilização da bengala, sendo analisadas variáveis espaciais, temporais e espaço-temporais. Foi feita análise estatística, com nível de significância de 5%. Os pr
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49

Lehne-Gstreinthaler, Christine. "Zu den klassischen Ursprüngen des Verjährungsrechts." Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Romanistische Abteilung 137, no. 1 (2020): 136–72. http://dx.doi.org/10.1515/zrgr-2020-0004.

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AbstractThe Roots of Prescription in Classical Roman Law: While it is widely presumed that prescription did not exist in Classical Roman Law, the author intends to show that, within certain areas of law, prescription was already in existence in Augustan times. The praescriptio temporis was used in penal and civil procedure alike and was submitted during preliminary proceedings. The most prominent prescription, the praescriptio longi temporis, stemmed from Roman fiscal law and potentially originated in Flavian times.
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Nasr, Odile, Miloud Rached, Jean-Paul Bodeveix, and Mamoun Filali. "Spécification et vérification d'un ordonnanceur en B via les automates temporisés." L'objet 14, no. 4 (2008): 43–72. http://dx.doi.org/10.3166/obj.14.4.43-72.

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