Journal articles on the topic 'Tenapanor'
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Block, Geoffrey A., David P. Rosenbaum, Andrew Yan, and Glenn M. Chertow. "Efficacy and Safety of Tenapanor in Patients with Hyperphosphatemia Receiving Maintenance Hemodialysis: A Randomized Phase 3 Trial." Journal of the American Society of Nephrology 30, no. 4 (2019): 641–52. http://dx.doi.org/10.1681/asn.2018080832.
Full textYuan, Gang, Yili Chen, Li Li, et al. "Pharmacokinetics, Safety, and Tolerability of Tenapanor in Healthy Chinese and Caucasian Volunteers: A Randomized, Open-Label, Single-Center, Placebo-Controlled Phase 1 Study." International Journal of Clinical Practice 2024 (March 6, 2024): 1–10. http://dx.doi.org/10.1155/2024/1386980.
Full textSuzuki, Naoki, Yuuki Takeda, Akie Kabuto, et al. "Efficacy of tenapanor in managing hyperphosphatemia and constipation in hemodialysis patients: A randomized controlled trial." PLOS One 20, no. 6 (2025): e0319319. https://doi.org/10.1371/journal.pone.0319319.
Full textDos Santos, Denise Francisca, Aloisio Pêgo Palacios Luz, Marly Sousa De Araújo, et al. "Tenapanor como terapia para hiperfosfatemia refratária em pacientes submetidos à diálise: revisão sistemática." Brazilian Journal of Health Review 7, no. 1 (2024): 7327–40. http://dx.doi.org/10.34119/bjhrv7n1-599.
Full textTan, Xinjie, Archana Kini, Dorothee Römermann, and Ursula Seidler. "The NHE3 Inhibitor Tenapanor Prevents Intestinal Obstructions in CFTR-Deleted Mice." International Journal of Molecular Sciences 23, no. 17 (2022): 9993. http://dx.doi.org/10.3390/ijms23179993.
Full textStamatopoulos, Konstantinos, Nena Mistry, Nikoletta Fotaki, David B. Turner, and Brandon Swift. "Physiologically Based Biopharmaceutics Model (PBBM) of Minimally Absorbed Locally Acting Drugs in the Gastrointestinal Tract—Case Study: Tenapanor." Pharmaceutics 15, no. 12 (2023): 2726. http://dx.doi.org/10.3390/pharmaceutics15122726.
Full textShigematsu, Takashi, Yotaro Une, Kazuaki Ikejiri, Hironori Kanda, Masafumi Fukagawa, and Tadao Akizawa. "Therapeutic Effects of Add-On Tenapanor for Hemodialysis Patients with Refractory Hyperphosphatemia." American Journal of Nephrology 52, no. 6 (2021): 496–506. http://dx.doi.org/10.1159/000516156.
Full textPergola, Pablo E., David P. Rosenbaum, Yang Yang, and Glenn M. Chertow. "A Randomized Trial of Tenapanor and Phosphate Binders as a Dual-Mechanism Treatment for Hyperphosphatemia in Patients on Maintenance Dialysis (AMPLIFY)." Journal of the American Society of Nephrology 32, no. 6 (2021): 1465–73. http://dx.doi.org/10.1681/asn.2020101398.
Full textMarkham, Anthony. "Tenapanor: First Approval." Drugs 79, no. 17 (2019): 1897–903. http://dx.doi.org/10.1007/s40265-019-01215-9.
Full textLin, Tiffany, Akram Al-Makki, and Brian Shepler. "Tenapanor: A new treatment option for hyperphosphatemia in end stage kidney disease." Journal of Pharmacy & Pharmaceutical Sciences 25 (January 16, 2022): 77–83. http://dx.doi.org/10.18433/jpps32284.
Full textCarney, Ellen F. "Efficacy of tenapanor in hyperphosphataemia." Nature Reviews Nephrology 13, no. 4 (2017): 194. http://dx.doi.org/10.1038/nrneph.2017.27.
Full textLobo, Leema, N. Kishore, and Manjari Sharma. "Tenapanor-A Novel Approach for Management of Hyperphosphatemia in End Stage Renal Disease: A Clinical Study Aggregate Review." Journal of Drug Delivery and Therapeutics 14, no. 1 (2024): 176–81. http://dx.doi.org/10.22270/jddt.v14i1.6336.
Full textRosenbaum, David P., Fredric O. Finkelstein, Yang Yang, Rebecca Galvin, and David M. Spiegel. "Impact of Tenapanor in Peritoneal Dialysis." Journal of the American Society of Nephrology 32, no. 10S (2021): 208. http://dx.doi.org/10.1681/asn.20213210s1208a.
Full textBrashier, D. B. S., Ajay Kumar, Anuj Singh, and Uday Pratap. "Tenapanor: new approach to counter irritable bowel syndrome with constipation." International Journal of Basic & Clinical Pharmacology 9, no. 7 (2020): 1180. http://dx.doi.org/10.18203/2319-2003.ijbcp20202961.
Full textCianciolo, C., S. Barbuto, F. Iacovella, et al. "An update on tenapanor to treat hyperphosphatemia." Drugs of Today 58, no. 1 (2022): 33. http://dx.doi.org/10.1358/dot.2022.58.1.3343689.
Full textSiddiqui, S., and B. D. Cash. "Tenapanor for constipation-predominant irritable bowel syndrome." Drugs of Today 56, no. 3 (2020): 203. http://dx.doi.org/10.1358/dot.2020.56.3.3115214.
Full textFadem, Stephen Z., David P. Tietjen, David M. Spiegel, Susan A. Edelstein, Yang Yang, and David P. Rosenbaum. "Patient Education Improves Tenapanor Tolerability in OPTIMIZE Study." Journal of the American Society of Nephrology 34, no. 11S (2023): 129. http://dx.doi.org/10.1681/asn.20233411s1129c.
Full textEdelstein, Susan A., Yang Yang, Brett Stephenson, Suling Zhao, Lynae Pagliaro, and Jeanene Fogli. "Patient-Reported Experience with Tenapanor in the OPTIMIZE Trial." Journal of the American Society of Nephrology 32, no. 10S (2021): 537–38. http://dx.doi.org/10.1681/asn.20213210s1537d.
Full textYin, Jianyi, Chung-Ming Tse, Boyoung Cha, et al. "A common NHE3 single-nucleotide polymorphism has normal function and sensitivity to regulatory ligands." American Journal of Physiology-Gastrointestinal and Liver Physiology 313, no. 2 (2017): G129—G137. http://dx.doi.org/10.1152/ajpgi.00044.2017.
Full textBlock, Geoffrey A., David P. Rosenbaum, Maria Leonsson-Zachrisson, et al. "Effect of Tenapanor on Serum Phosphate in Patients Receiving Hemodialysis." Journal of the American Society of Nephrology 28, no. 6 (2017): 1933–42. http://dx.doi.org/10.1681/asn.2016080855.
Full textSinagra, Emanuele, Francesca Rossi, Dario Raimondo, et al. "Tenapanor for the treatment of irritable bowel syndrome with constipation." Expert Review of Clinical Pharmacology 13, no. 5 (2020): 473–79. http://dx.doi.org/10.1080/17512433.2020.1762570.
Full textSoeda, Keisuke, and Hirotaka Komaba. "Navigating How to Initiate Tenapanor Therapy in the Real World." Kidney360 5, no. 7 (2024): 938–40. http://dx.doi.org/10.34067/kid.0000000000000488.
Full textVisconti, Luca, Valeria Cernaro, Sebastiano Calimeri, et al. "The Myth of Water and Salt: From Aquaretics to Tenapanor." Journal of Renal Nutrition 28, no. 2 (2018): 73–82. http://dx.doi.org/10.1053/j.jrn.2017.06.005.
Full textJohansson, Susanne, David P. Rosenbaum, Marie Ahlqvist, et al. "Effects of Tenapanor on Cytochrome P450-Mediated Drug-Drug Interactions." Clinical Pharmacology in Drug Development 6, no. 5 (2017): 466–75. http://dx.doi.org/10.1002/cpdd.346.
Full textRobinson, Jennifer, Chris Dudzenski, and Denise Foy. "Nephrologists Frustrated With FDA Decisions on Roxadustat, Vadadustat, and Tenapanor." Journal of the American Society of Nephrology 33, no. 11S (2022): 929. http://dx.doi.org/10.1681/asn.20223311s1929c.
Full textShima, Hisato, Hiroyoshi Nakatsuji, Manabu Sakaki, Yoshihide Murakami, and Takumi Hamao. "Tenapanor‒induced drug eruption in hemodialysis patient: A case report." Nihon Toseki Igakkai Zasshi 58, no. 4 (2025): 215–18. https://doi.org/10.4009/jsdt.58.215.
Full textSijabat, Landong, and Guinanti Novettiandari. "PHARMACOLOGIC TREATMENT OF THE IRRITABLE BOWEL SYNDROME: A COMPREHENSIVE SYSTEMATIC REVIEW." Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425) 10, no. 5 (2024): 26–34. http://dx.doi.org/10.61841/ypxr6c52.
Full textBlock, Geoffrey A., David P. Rosenbaum, Maria Leonsson-Zachrisson, et al. "Effect of Tenapanor on Interdialytic Weight Gain in Patients on Hemodialysis." Clinical Journal of the American Society of Nephrology 11, no. 9 (2016): 1597–605. http://dx.doi.org/10.2215/cjn.09050815.
Full textAkizawa, Tadao, Yu Sato, Kazuaki Ikejiri, Hironori Kanda, and Masafumi Fukagawa. "Effect of Tenapanor on Phosphate Binder Pill Burden in Hemodialysis Patients." Kidney International Reports 6, no. 9 (2021): 2371–80. http://dx.doi.org/10.1016/j.ekir.2021.06.030.
Full textZielińska, Marta, Andrzej Wasilewski, and Jakub Fichna. "Tenapanor hydrochloride for the treatment of constipation-predominant irritable bowel syndrome." Expert Opinion on Investigational Drugs 24, no. 8 (2015): 1093–99. http://dx.doi.org/10.1517/13543784.2015.1054480.
Full textOkada, Kazuyoshi, Manabu Tashiro, Ikuko Shimizu, Tomoko Inoue, and Jun Minakuchi. "Impact of switching from lanthanum carbonate to tenapanor on CKD‒MBD management." Nihon Toseki Igakkai Zasshi 58, no. 1 (2025): 31–33. https://doi.org/10.4009/jsdt.58.31.
Full textMoro, L. "Tenapanor. Na+/H+ exchanger 3 (NHE3) inhibitor, Treatment of gastrointestinal and cardiorenal diseases." Drugs of the Future 43, no. 6 (2018): 395. http://dx.doi.org/10.1358/dof.2018.043.06.2802349.
Full textLi, Qian, Andrew J. King, Liansheng Liu, Yaohui Zhu, Jeremy S. Caldwell, and Pankaj J. Pasricha. "Tenapanor Reduces IBS Pain Through Inhibition of TRPV1-Dependent Neuronal Hyperexcitability In vivo." American Journal of Gastroenterology 112 (October 2017): S255. http://dx.doi.org/10.14309/00000434-201710001-00484.
Full textJohansson, Susanne A., Mikael Knutsson, Maria Leonsson-Zachrisson, and David P. Rosenbaum. "Effect of Food Intake on the Pharmacodynamics of Tenapanor: A Phase 1 Study." Clinical Pharmacology in Drug Development 6, no. 5 (2017): 457–65. http://dx.doi.org/10.1002/cpdd.341.
Full textLacy, Brian, Yang Yang, and David Rosenbaum. "S171 Tenapanor Treatment Success for IBS-C Symptoms Increases with Duration of Therapy." American Journal of Gastroenterology 118, no. 10S (2023): S129. http://dx.doi.org/10.14309/01.ajg.0000950324.37170.3f.
Full textStephenson, B., G. Chertow, Y. Yang, and D. Rosenbaum. "PUK2 Hospitalization in Patients Receiving Maintenance Dialysis with Hyperphosphatemia Randomized to Tenapanor or Sevelamer." Value in Health 24 (June 2021): S234. http://dx.doi.org/10.1016/j.jval.2021.04.1170.
Full textJohansson, Susanne, David P. Rosenbaum, Johan Palm, et al. "Tenapanor administration and the activity of the H+-coupled transporter PepT1 in healthy volunteers." British Journal of Clinical Pharmacology 83, no. 9 (2017): 2008–14. http://dx.doi.org/10.1111/bcp.13313.
Full textRosenbaum, David P., Andrew Yan, and Jeffrey W. Jacobs. "Pharmacodynamics, Safety, and Tolerability of the NHE3 Inhibitor Tenapanor: Two Trials in Healthy Volunteers." Clinical Drug Investigation 38, no. 4 (2018): 341–51. http://dx.doi.org/10.1007/s40261-017-0614-0.
Full textPace, Rory C., David P. Tietjen, David M. Spiegel, et al. "The Positive Impact of Patient Education on Tenapanor Adherence 295 in the OPTIMIZE Study." Nephrology Nursing Journal 52, no. 3 (2025): 295. https://doi.org/10.37526/1526-744x.2025.52.3.295.
Full textB., Akhila N. Navya Sree K. Mounika M. Sreya E. Anusha B. Manasa. "A Review on FDA Approved Drugs for Chronic Kidney Disease." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 966–76. https://doi.org/10.5281/zenodo.14339742.
Full textJohansson, Susanne, Maria Leonsson-Zachrisson, Mikael Knutsson, et al. "Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders." Clinical Pharmacology in Drug Development 6, no. 5 (2016): 448–56. http://dx.doi.org/10.1002/cpdd.307.
Full textSilva, Arnold L., German T. Hernandez, David M. Spiegel, et al. "Safety Analysis of Tenapanor Monotherapy vs. Sevelamer Carbonate in Patients on Maintenance Dialysis with Hyperphosphatemia." Journal of the American Society of Nephrology 34, no. 11S (2023): 129. http://dx.doi.org/10.1681/asn.20233411s1129b.
Full textCernaro, Valeria, Elisa Longhitano, Chiara Casuscelli, Luigi Peritore, and Domenico Santoro. "Hyperphosphatemia in Chronic Kidney Disease: The Search for New Treatment Paradigms and the Role of Tenapanor." International Journal of Nephrology and Renovascular Disease Volume 17 (May 2024): 151–61. http://dx.doi.org/10.2147/ijnrd.s385826.
Full textBlock, Geoffrey A., David P. Rosenbaum, Andrew Yan, Peter J. Greasley, Glenn M. Chertow, and Myles Wolf. "The effects of tenapanor on serum fibroblast growth factor 23 in patients receiving hemodialysis with hyperphosphatemia." Nephrology Dialysis Transplantation 34, no. 2 (2018): 339–46. http://dx.doi.org/10.1093/ndt/gfy061.
Full textKing, Andrew J., Matthew Siegel, Ying He, et al. "Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability." Science Translational Medicine 10, no. 456 (2018): eaam6474. http://dx.doi.org/10.1126/scitranslmed.aam6474.
Full textHerekar, Anam, Dhanush Shimoga, Asad Jehangir, et al. "Tenapanor in the Treatment of Irritable Bowel Syndrome with Constipation: Discovery, Efficacy, and Role in Management." Clinical and Experimental Gastroenterology Volume 16 (June 2023): 79–85. http://dx.doi.org/10.2147/ceg.s384251.
Full textLembo, Anthony, Susan Edelstein, Yang Yang, and David P. Rosenbaum. "Mo1396: LONG TERM TREATMENT WITH TENAPANOR IMPROVES ABDOMINAL PAIN AND OTHER ABDOMINAL SYMPTOMS ASSOCIATED WITH IBS-C." Gastroenterology 162, no. 7 (2022): S—757. http://dx.doi.org/10.1016/s0016-5085(22)61788-8.
Full textInaba, Masaaki, Yotaro Une, Kazuaki Ikejiri, Hironori Kanda, Masafumi Fukagawa, and Tadao Akizawa. "Dose-Response of Tenapanor in Patients With Hyperphosphatemia Undergoing Hemodialysis in Japan—A Phase 2 Randomized Trial." Kidney International Reports 7, no. 2 (2022): 177–88. http://dx.doi.org/10.1016/j.ekir.2021.11.008.
Full textJohansson, Susanne, David P. Rosenbaum, Mikael Knutsson, and Maria Leonsson-Zachrisson. "A phase 1 study of the safety, tolerability, pharmacodynamics, and pharmacokinetics of tenapanor in healthy Japanese volunteers." Clinical and Experimental Nephrology 21, no. 3 (2016): 407–16. http://dx.doi.org/10.1007/s10157-016-1302-8.
Full textSprague, Stuart M., Jill M. Meyer, David P. Rosenbaum, Yang Yang, Suling Zhao, and David M. Spiegel. "Optimal Initiation of Tenapanor Treatment Analyzed by Baseline Phosphate Binder Dose: A Subanalysis of the OPTIMIZE Study." Journal of the American Society of Nephrology 34, no. 11S (2023): 128. http://dx.doi.org/10.1681/asn.20233411s1128c.
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