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Dissertations / Theses on the topic 'Tendon graft'

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1

Alam, Nawsheen. "The cellular biology of tendon grafting and graft integration." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/the-cellular-biology-of-tendon-grafting-and-graft-integration(ae75cfd2-86f4-4d5d-9511-edca52d2a6f6).html.

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Background: Prolonged recovery after tendon injury has given rise to the need for innovative therapy including tendon engineering and cell based therapies. The role of cells in grafted or engineered tendon is poorly understood. Clarifying the persistence of grafted tissue is fundamentally important to ensure that tissue engineering strategies are fit for clinical application. We have devised a murine model for tendon grafting that allows for cell tracking and the assessment of tendon integration and engineered construct integration. Materials and methods: We studied the macroscopic and microsc
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2

Mikkelsen, Christina. "Rehabilitation following bone-patellar tendon-bone graft ACL reconstruction /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-913-0/.

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3

Elnikety, S. "A new application of demineralised bone as a tendon graft." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1473214/.

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Tendon injuries present a challenging situation for orthopaedic surgeons. In severe injuries, a tendon transfer or a tendon graft is usually used. The aim is to find a biocompatible substance with mechanical and structural properties that replicate those of normal tendon. Because of its structural and mechanical properties, we propose that Demineralised Cortical Bone (DCB) can be used in the repair of tendon and ligament, as well as for the regeneration of the enthesis. I hypothesise that DCB grafted in a tendon environment will result in remodelling of the DCB into tendon and produce a fibroc
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4

Möller, Eva. "Anterior cruciate ligament reconstruction with bone-patellar tendon-bone graft : postoperative intervention and influential factors for patient-relevant long-term outcome /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-198-2/.

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5

Ringer, Geoffrey Wadsworth. "Evaluation of Graft Pretension Effects in Anterior Cruciate Ligament Reconstruction: A Series of In Vitro and In Vivo Experiments." Diss., Virginia Tech, 1998. http://hdl.handle.net/10919/40494.

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The purpose of this dissertation was to study the effects of graft pretension in anterior cruciate ligament (ACL) reconstruction through a series of experiments. First, an in vitro study of 5 human knees was conducted to determine if intact joint kinematics could be restored when using the ideal graft - the intrinsic ACL. The ACL tibial insertion site was freed, and pretensions of 0, 10, 20, 30, and 40 N were applied to the ligament using a custom designed load cell connection. Kinematics during a simulated active extension were compared to those of the intact knee. Intact knee kinematics were
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6

Hernández, Tovar María Cristina [UNESP]. "Implantes de matrizes de colágeno isoladas ou associadas às células estromais mesenquimais multipotentes autólogas na reparação tendínea em ovinos." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/101154.

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Made available in DSpace on 2014-06-11T19:31:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-11-27Bitstream added on 2014-06-13T21:02:18Z : No. of bitstreams: 1 hernandeztovar_mc_dr_jabo.pdf: 3642290 bytes, checksum: c426af96b828f5acd5ad320a0cdb0514 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Este projeto tem como proposta avaliar o comportamento biológico das células estromais mesenquimais multipotentes autólogas associadas ou não às matrizes de colágeno, na reconstrução tendínea. Optou-se em trabalhar com ovinos e, para isso, os ovinos foram submetid
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7

Hernández, Tovar María Cristina. "Implantes de matrizes de colágeno isoladas ou associadas às células estromais mesenquimais multipotentes autólogas na reparação tendínea em ovinos /." Jaboticabal : [s.n.], 2009. http://hdl.handle.net/11449/101154.

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Resumo: Este projeto tem como proposta avaliar o comportamento biológico das células estromais mesenquimais multipotentes autólogas associadas ou não às matrizes de colágeno, na reconstrução tendínea. Optou-se em trabalhar com ovinos e, para isso, os ovinos foram submetidos à ferida no tendão flexor superficial do membro torácico esquerdo, que consistiu na realização de uma tenectomia parcial medindo 1,5cm de comprimento e 0,3cm de largura. Aos 30, 60 e 90 dias após o procedimento cirúrgico foram retirados os tendões flexores superficiais dos membros torácicos dos animais e os fragmentos colhi
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8

Kuang, Guanming, and 邝冠明. "Preparation of a strontium enriched calcium phosphate cement and its use in accelerating the healing of a soft tissue tendon graft within the bone tunnel in a rabbit anterior cruciate ligament reconstruction model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hdl.handle.net/10722/193043.

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Anterior cruciate ligament (ACL) rupture is a major clinical problem in sports medicine. The current mainstay of treatment is arthroscopic-assisted ACL reconstruction with a soft tissue tendon graft. However, the affected patients are required to abstain from any pivoting activity for at least six to nine months after the operation to protect the graft-host bone interface in order to allow the graft to heal. In this study, a method to accelerate the graft healing within the bone tunnel is proposed by using a local application of an osteoconductive bone cement (Strontium enriched calcium pho
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9

Czarnecki, Jarema S. "Engineered carbon-based scaffolds for hard and soft tissue repair, reconstruction or regeneration." University of Dayton / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1386953861.

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10

Venter, Gerda. "Morphology of the palmaris longus and plantaris muscles employed as flaps in reconstructive surgery." Diss., University of Pretoria, 2011. http://hdl.handle.net/2263/24880.

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Tendons are frequently used for reconstructive surgery. This includes palmaris longus, plantaris, the long extensors of the toes and fingers as well as the flexors of the fingers. The surgeon must base his or her selection of the donor tendon for grafting on what is needed, for example tendon size, length, and width. The most desirable tendons in reconstructive surgery are the palmaris longus and plantaris tendons. These two muscles are also considered to be the easiest tendons to harvest, and therefore they remain the ideal choices for plantaris,or tendon grafts. Apart from what is mentioned
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11

Dinevski, Elizabeth. "Randomized clinical trial assessing the effects of graft tensioning using semitendinosus and gracilis tendons in anterior cruciate ligament reconstruction." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0005/MQ42140.pdf.

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12

Heijne, Annette. "Rehabilitation after anterior cruciate ligament reconstruction using patellar tendon or hamstring grafts : open and closed kinetic chain exercises /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-126-5/.

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13

Francis, Monika K. "Regulation of GRAF1 membrane sculpting function during cell movement." Doctoral thesis, Umeå universitet, Institutionen för medicinsk kemi och biofysik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-111213.

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All eukaryotic cells rely on endocytic events to satisfy a constant need for nutrient and fluid uptake from their surroundings. Endocytosis-dependent turnover of cell surface constituents also serves to control signal transduction and establish morphological changes in response to extracellular stimuli. During endocytosis, distinct protein machineries re-sculpt the plasma membrane into vesicular carriers that enclose molecules that are to be taken up into the cell. Besides those produced from the canonical clathrin-mediated endocytic machinery, it is becoming increasingly clear that other memb
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14

Magaton, Marina. "Élaboration et caractérisation de nanocomposites à base de mélanges polystyrène/polyamide 6 et d'argile montmorillonite." Thesis, Vandoeuvre-les-Nancy, INPL, 2010. http://www.theses.fr/2010INPL072N/document.

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Ce travail concerne l’élaboration de nanocomposites à base de polystyrène/polyamide 6/argile montmorillonite (PS/PA6/MMT). Son but premier a été d’évaluer l’influence d’un copolymère polystyrène greffé polyamide 6 (PS-g-PA6), en tant qu’agent compatibilisant pour promouvoir une meilleure interaction PS-PA6, et son influence dans l’intercalation/exfoliation des argiles, d’une part ; évaluer les structures et les propriétés des nanocomposites obtenus. Deux sortes d’argile montmorillonite ayant différents modificateurs organiques, bien que cinq sortes de PS-g-PA6 contenant différentes quantités d
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15

Kumar, Vivek Ashok. "Design and evaluation of scaffolds for arterial grafts using extracellular matrix based materials." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/45869.

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For small diameter (<6 mm) blood vessel replacements, lack of collaterals and vascular disease preclude homografts; while synthetic analogs, ePTFE, expanded polytetrafluoroethylene, and PET, polyethyleneterephathalate, are prone to acute thrombosis and restenosis. It is postulated that the hierarchical assembly of cell populated matrices fabricated from protein analogs provides a new design strategy for generating a structurally viable tissue engineered vascular graft. To this end, synthetic elastin and collagen fiber analogs offer a novel strategy for creating tissue engineered vascular graft
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16

Gruel, Roxane. "Etude des mécanismes sous-tendant la récupération fonctionnelle post-AVC associée à la transplantation différée de cellules hADSC exprimant le neuropeptide PACAP. Cortical interhemispheric connections reshaping supports post-stroke functional recovery mediated by PACAP-expressing hADSC graft." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR098.

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Malgré plus de deux décennies de recherches intensives, les accidents vasculaires cérébraux (AVC) demeurent l'une des principales causes de décès et d'invalidité dans le monde. À ce jour, les seules thérapies admises pour le traitement des AVC ischémiques sont les techniques de reperfusion,restreintes à une très courte fenêtre thérapeutique, puis ensuite la rééducation neurologique. Bien que ces interventions améliorent grandement le devenir des patients, le nombre de personnes éligibles à la reperfusion et la récupération fonctionnelle post-ischémique induite par des exercices de rééducation
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17

Aleksandar, Đuričin. "Prostorno određivanje položaja kalema u golenjači posle rekonstrukcije prednjeg ukrštenog ligamenta kolena." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2018. https://www.cris.uns.ac.rs/record.jsf?recordId=107200&source=NDLTD&language=en.

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Osnovni cilj rekonstrukcije prednjeg ukr&scaron;tenog ligamenta kolena je dobijanje pune stabilnosti kolena u celom obimu pokreta. Bez obzira na razvoj operativne tehnike i rehabilitacije i dalje postoji jedan broj pacijenata koji nije u potpunosti zadovoljan rezultatom rekonstrukcije prednjeg ukr&scaron;tenog ligamenta kolena, te je potrebno izvr&scaron;iti ponovnu operaciju. Smatra se da je najče&scaron;ći uzrok rane ponovne nestabilnosti lo&scaron;a pozicija kalema, tj. pozicija tunela koja nije na anatomskom mestu. Većina hirurga koji se bave ovom problematikom procenjuju poziciju kalema u
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18

Sincos, Igor Rafael. "Determinação do impacto do oversizing da endoprótese sobre a aorta torácica. Estudo experimental em porcos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-22012013-160615/.

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Introdução: A utilização da técnica endovascular para tratar as diversas afecções da aorta têm suplantado as técnicas abertas tradicionais, sendo particularmente promissora no trauma 1. A ruptura traumática da aorta é a segunda causa de morte por acidente de trânsito 2,3; e o reparo endoluminal dessas lesões com endopróteses apresenta menor taxa de mortalidade e paraplegia quando comparada a cirurgia aberta, no entanto os resultados a longo prazo ainda não estão disponíveis2-7. As próteses aprovadas e comercialmente disponíveis, até o momento desse estudo, foram desenhadas para doença aneurism
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19

Serpe, Gaétan. "Morphologie et permeabilite des melanges polyethylene-polyamide." Paris 6, 1988. http://www.theses.fr/1988PA066536.

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Etude des proprietes hydrodynamiques du melange (vitesse de cisaillement, temperature, tension interfaciale, viscosite) et de la technique de mise en forme utilisee en relation avec la taille moyenne de la dispersion. Analyse de la morphologie montrant que la taille moyenne de la phase dispersee resulterait d'un equilibre entre un effet de fragmentation et un effet de coalescence des nodules. Formation d'un copolymere greffe par addition au melange d'un copolymere ethylene-anhydride maleique
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20

Carvalho, Diogo Miguel Magalhães da Rocha de. "Anterior Cruciate Ligament Reconstruction with Patellar Tendon Graft vs Hamstrings Graft: Isokinetic Comparative Study." Master's thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/90152.

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21

Carvalho, Diogo Miguel Magalhães da Rocha de. "Anterior Cruciate Ligament Reconstruction with Patellar Tendon Graft vs Hamstrings Graft: Isokinetic Comparative Study." Dissertação, 2016. https://repositorio-aberto.up.pt/handle/10216/90152.

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22

Wu, Jia-Lin, and 吳家麟. "Mechanical Comparison of Biodegradable Femoral Fixation Devices for Hamstring Tendon Graft-A Porcine Biomechanical Study." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/85963916107901208091.

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碩士<br>國立陽明大學<br>醫學工程研究所<br>96<br>Abstract Purpose: Initial fixation strength is critical for the early post-operative rehabilitation of patients with anterior cruciate ligament (ACL) reconstructions. However, even the best femoral fixation devices remain controversial. We compared the biomechanical characteristics of tendon grafts fixed by different biodegradable femoral fixation devices following ACL reconstruction. Methods: The Bio-TransFix, Rigidfix, Bioscrew with EndoPearl augmentation and Bioscrew devices were used to fix porcine flexor digitorum profundus tendon grafts in 32 porcine femo
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23

Green, Bradley. "Comparing anterior cruciate ligament graft choice during reconstructive surgery: a literature review revisiting the quadricep tendon." Thesis, 2018. https://hdl.handle.net/2144/32979.

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ACL injuries are ubiquitous and the literature surrounding ACL reconstructions is complex and difficult to comprehend. In summary, this paper provides a simple yet coherent overview of ACL injuries. Etiology, prevention, and the consequences of injury are discussed. The paper examines literature surrounding the decision to reconstruct the anterior cruciate ligament. An overwhelming quantity of literature is in favor of an ACL reconstruction in order to maintain an active lifestyle. ACL surgery has advanced exponentially in recent years and there is a multitude of fixation and tunneling methods
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24

"The influence of bone adaptive changes on graft incorporation after anterior cruciate ligament reconstruction: an experimental study." Thesis, 2009. http://library.cuhk.edu.hk/record=b6074727.

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In conclusion, the present study firstly addressed the relationship between graft incorporation and peri-graft bone quality and quantity after ACL reconstruction in a rabbit model. The findings suggested that the non-invasive measurement of peri-graft bone would be useful to predict graft incorporation. Peri-graft bone loss was region-specific after surgery, which might be associated with stress shielding in the specific region after tunnel creation. The use of Brushite CPC might be a promising way to augment peri-graft bone and enhance graft incorporation. (Abstract shortened by UMI.)<br>In t
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25

Pešlová, Kateřina. "Fyzioterapeutické postupy u pacientů po operaci předního zkříženého vazu." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-308704.

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Title: Physical therapy procedures in patients following the operation of the anterior cruciate ligament Objectives: The main objective of this work is to determine the influence of the chosen method of reconstruction and subsequent physiotherapy on the final status of the patient. And also if the group physiotherapy is the ideal therapeutic approach. Methods: In quantitative research the numerical analysis of the data was performed. Comparison of individual groups was performed simply through finding the frequency distribution of individual characters. Evaluated were the basic sets A (patient
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26

Gameiro, Rafael Capêlo Leite. "Development of Flexible Bone Grafts." Master's thesis, 2018. http://hdl.handle.net/10362/39804.

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With the aging of world’s population, diseases and bone related problems are becoming more frequent. Bone grafts are normally used in the treatment and repair of bone defects. The aim of this project was to develop a flexible bone graft in order to be adjustable to the patient's problem. The development of this product consisted in combining a natural protein, type I collagen, extracted from bovine tendon, with β-TCP, a calcium phosphate. The composition of this product was 10:90 wt%, respectively. Its production focused in a lyophilization cycle and posteriorly Dehydrothermal crosslinking, u
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27

"Synthesis and Characterization of Novel Silicone Graft Copolymers." Master's thesis, 2016. http://hdl.handle.net/2286/R.I.39413.

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abstract: Silicone compounds have a very low surface energy due to highly flexible Si-O-Si backbone and large number of –CH3 groups, but these compounds are extremely hydrophobic and thus have limited applications in aqueous formulations. Modification of such silicone compounds by grafting hydrophilic chains provides a wide range of silicone products called "Silicone Surfactants". Silicone surfactants are surface active agents which get adsorbed at the air-water interface thereby, reducing the interfacial tension. Some of the larger applications of silicone surfactant are in the manufacture of
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28

Li, Chun-Hsien, and 李俊賢. "The Comparison of Patellar Alignment, Knee Strength, and One Leg Hopping Strategies between Bone-Patellar Tendon-Bone and Hamstring Tendon Grafts for Anterior Cruciate Ligament Reconstruction." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/30979257056810703179.

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碩士<br>國立成功大學<br>物理治療研究所<br>96<br>Background: Anterior cruciate ligament (ACL) injury is the commonest knee injury and it’s prevalence is up to 85% of knee internal tissue injuries. Recently, bone-patellar tendon-bone autograft (BPTBA) and hamstrings tendon autograft (HTA) have been generally recommended for conducting ACL reconstruction (ACLR) surgery. Numerous studies have compared knee function, knee joint laxity, knee strength, and gait analysis between these two different grafts of ACLR for seeking a better way of surgery. On the other hand, one leg hopping test has been widely used to
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