Academic literature on the topic 'Tendon healing'

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Journal articles on the topic "Tendon healing"

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Hope, Matthew, and Terry S. Saxby. "Tendon Healing." Foot and Ankle Clinics 12, no. 4 (December 2007): 553–67. http://dx.doi.org/10.1016/j.fcl.2007.07.003.

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Al-Qattan, Mohammad M., Jeffrey C. Posnick, Kant Y. Lin, and Paul Thorner. "Fetal Tendon Healing." Plastic and Reconstructive Surgery 92, no. 6 (November 1993): 1155–60. http://dx.doi.org/10.1097/00006534-199311000-00024.

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Al-Qattan, Mohammad M., Jeffrey C. Posnick, Kant Y. Lin, Paul Thorner, and John A. I. Grossman. "Fetal Tendon Healing." Plastic and Reconstructive Surgery 92, no. 6 (November 1993): 1161. http://dx.doi.org/10.1097/00006534-199311000-00025.

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MANSKE, P. "Flexor tendon healing." Journal of Hand Surgery: Journal of the British Society for Surgery of the Hand 13, no. 3 (August 1988): 237–45. http://dx.doi.org/10.1016/0266-7681(88)90077-0.

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Manske, Paul R., Richard H. Gelberman, and Peggy A. Lesker. "Flexor Tendon Healing." Hand Clinics 1, no. 1 (February 1985): 25–34. http://dx.doi.org/10.1016/s0749-0712(21)01329-9.

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Chartier, Christian, Hassan ElHawary, Aslan Baradaran, Joshua Vorstenbosch, Liqin Xu, and Johnny Ionut Efanov. "Tendon: Principles of Healing and Repair." Seminars in Plastic Surgery 35, no. 03 (July 15, 2021): 211–15. http://dx.doi.org/10.1055/s-0041-1731632.

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AbstractTendon stores, releases, and dissipates energy to efficiently transmit contractile forces from muscle to bone. Tendon injury is exceedingly common, with the spectrum ranging from chronic tendinopathy to acute tendon rupture. Tendon generally develops according to three main steps: collagen fibrillogenesis, linear growth, and lateral growth. In the setting of injury, it also repairs and regenerates in three overlapping steps (inflammation, proliferation, and remodeling) with tendon-specific durations. Acute injury to the flexor and extensor tendons of the hand are of particular clinical
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Hayashi, M., C. Zhao, K. N. An, and P. C. Amadio. "The effects of growth and differentiation factor 5 on bone marrow stromal cell transplants in an in vitro tendon healing model." Journal of Hand Surgery (European Volume) 36, no. 4 (May 2011): 271–79. http://dx.doi.org/10.1177/1753193410394521.

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The effects of growth differentiation factor-5 (GDF-5) and bone marrow stromal cells (BMSCs) on tendon healing were investigated under in vitro tissue culture conditions. BMSCs and GDF-5 placed in a collagen gel were interpositioned between the cut ends of dog flexor digitorum profundus tendons. The tendons were randomly assigned into four groups: 1) repaired tendon without gel; 2) repaired tendon with BMSC-seeded gel; 3) repaired tendon with GDF-5 gel without cells; and 4) repaired tendon with GDF-5 treated BMSC-seeded gel. At 2 and 4 weeks, the maximal strength of repaired tendons with GDF-5
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Müller, Sebastian A., Nicholas P. Quirk, Julia A. Müller-Lebschi, Patricia E. Heisterbach, Lutz Dürselen, Martin Majewski, and Christopher H. Evans. "Response of the Injured Tendon to Growth Factors in the Presence or Absence of the Paratenon." American Journal of Sports Medicine 47, no. 2 (December 14, 2018): 462–67. http://dx.doi.org/10.1177/0363546518814534.

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Background: The paratenon is important for Achilles tendon healing. There is much interest in the use of exogenous growth factors (GFs) as potential agents for accelerating the healing of damaged Achilles tendons. Purpose/Hypothesis: The present study used a rat model to study the responses of the injured Achilles tendon to GFs in the presence or absence of the paratenon. The hypothesis was that responses of the injured tendon to GFs would be lower in the absence of a paratenon. Study Design: Controlled laboratory study. Methods: A 4-mm defect was created in the right Achilles tendon of 60 ske
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Freedman, Benjamin R., Ashley B. Rodriguez, Cody D. Hillin, Stephanie N. Weiss, Biao Han, Lin Han, and Louis J. Soslowsky. "Tendon healing affects the multiscale mechanical, structural and compositional response of tendon to quasi-static tensile loading." Journal of The Royal Society Interface 15, no. 139 (February 2018): 20170880. http://dx.doi.org/10.1098/rsif.2017.0880.

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Tendon experiences a variety of multiscale changes to its extracellular matrix during mechanical loading at the fascicle, fibre and fibril levels. For example, tensile loading of tendon increases its stiffness, with organization of collagen fibres, and increases cell strain in the direction of loading. Although applied macroscale strains correlate to cell and nuclear strains in uninjured tendon, the multiscale response during tendon healing remains unknown and may affect cell mechanosensing and response. Therefore, this study evaluated multiscale structure–function mechanisms in response to qu
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Yu, Tung-Yang, Jong-Hwei S. Pang, Li-Ping Lin, Ju-Wen Cheng, Shih-Jung Liu, and Wen-Chung Tsai. "Platelet-Rich Plasma Releasate Promotes Early Healing in Tendon After Acute Injury." Orthopaedic Journal of Sports Medicine 9, no. 4 (April 1, 2021): 232596712199037. http://dx.doi.org/10.1177/2325967121990377.

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Background: Acute tendon injury can limit motion and thereby inhibit tendon healing. Positive results have been found after the use of platelet-rich plasma (PRP) to treat tendon injury; however, the early effects of PRP on tendon regeneration are not known. Purpose/Hypothesis: The purpose of this study was to evaluate the effects of PRP releasate (PRPr) on the early stages of tendon healing in a rat partial tenotomy model. It was hypothesized that PRPr can promote early healing of an Achilles tendon in rats. Study Design: Controlled laboratory study. Methods: PRP was prepared by a 2-step metho
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Dissertations / Theses on the topic "Tendon healing"

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Blomgran, Parmis. "Inflammation and tendon healing." Doctoral thesis, Linköpings universitet, Avdelningen för Kirurgi, Ortopedi och Onkologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-142349.

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Tendons heal through three different overlapping phases; the inflammatory, proliferative and remodeling phase. Many studies have investigated what factors influence healing of tendons. However, little was known about inflammation and the immune cells present during Achilles tendon healing by the time this thesis started. We developed a flow cytometry method for our rat model of tendon healing, which enabled us to study different leukocyte subpopulations during Achilles tendon healing. The general aim of this thesis was to understand more about inflammation and the immune cell populations prese
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Murrell, George Anthony Calvert St George Clinical School UNSW. "Nitric oxide and tendon healing." Awarded by:University of New South Wales. St George Clinical School, 2006. http://handle.unsw.edu.au/1959.4/31887.

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Nitric oxide is a small free radical generated by family of enzymes, the nitric oxide synthases. In a series of experiments performed over the last 15 years we showed that nitric oxide is induced by all three isoforms of nitric oxide synthase during tendon healing and that it plays a crucial beneficial role in restoring tendon function. In normal tendon we found very little nitric oxide synthase activity while in injured rat and human tendons nitric oxide synthase activity was expressed in healing fibroblasts in a temporal fashion. In healing rat Achilles tendon fibroblasts the first isoform
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Molloy, Timothy John St George Clinical School UNSW. "Gene expression in healing tendon." Awarded by:University of New South Wales. St George Clinical School, 2006. http://handle.unsw.edu.au/1959.4/23939.

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Tendon injury is painful and often debilitating, and is a one of the most prevalent soft tissue injuries encountered in the clinic. While common, the underlying molecular and genetic processes of tendon damage and repair remain poorly understood. The work described herein used genome-wide expression analyses to investigate tendon injury and healing from three perspectives. The first identified novel gene expression in tendon fibroblasts following their stimulation with nitric oxide (NO). Of particular relevance to tendon healing was the observation that stimulated fibroblasts express a number
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Berglund, Maria. "Biomolecular Aspects of Flexor Tendon Healing." Doctoral thesis, Uppsala universitet, Handkirurgi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-120304.

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Flexor tendon injuries in zone II of the hand (i.e. between the distal volar crease and the distal interphalangeal joint) can be costly for both the afflicted individual and society because of the high cost of a long rehabilitation period, complicated by tendon ruptures or scarring with adhesion formation, causing impaired range of motion. The aim of the present thesis was to characterize more fully the deep flexor tendon, the tendon sheath and their response to injury in a rabbit model in order to find potential targets to improve the outcome of repair. The intrasynovial rabbit deep flexor te
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Schepull, Thorsten. "Stiffness of the healing human Achilles tendon." Doctoral thesis, Linköpings universitet, Institutionen för klinisk och experimentell medicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-91727.

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Achilles tendon ruptures in humans are followed by a long period of immobilisation, rehabilitation and limitations of physical activity and sometimes work also. This prolonged period probably leaves a marginal for improvement in the management of this injury. Animal studies have shown that there are several possibilities to influence and improve tendon healing. The aim of this thesis was to find a way to examine the mechanical properties of the healing human Achilles tendon and, by using that method, to gain a better understanding of the tissue properties and healing process in these tendons.
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Brooks, Jonathan Peter. "The biology of the tendon in development and healing." Thesis, University of Manchester, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488287.

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The biology of tendons has been extensively investigated previously. Many studies have looked into the development and healing of tendons. An overall picture of the events in tendon development and healing, in terms of recently recognised functional molecules is missing, particularly in a single model. The recent understanding of the importance of metalloproteinases and other enzymes in ECM degradation suggests they may be of importance in tendon healing and development. Another unexplored area with relevance to wound healing and development is the functional integrin molecules. This thesis lo
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Stevenson, John Howard. "An investigation into the effect of ultrasound on repaired tendons." Thesis, Queen's University Belfast, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335315.

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Harrison, R. "The elucidation and strategic modification of flexor tendon healing mechanisms." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1445576/.

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Introduction and aims: 16,000 flexor tendon repair operations are performed annually in the UK these are frequently complicated by adhesions, causing significant morbidity. The uncertainty over which cells are responsible for the tendon healing mechanisms persists. We aimed to develop a novel experimental model to elucidate the possible role and migratory response of synovial sheath fibroblasts during tendon healing and to determine the effects of differing environment and stimuli on the cellular processes in the healing tendon. 0.1.2 Materials and methods: Rat synovial sheath cells were label
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Virchenko, Olena. "Stimulation of tendon repair by platelet concentrate, CDMP-2 and mechanical loading in animal models." Doctoral thesis, Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med1005s.pdf.

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Kinneberg, Kirsten R. C. "Tissue Engineering Strategies to Improve Tendon Healing and Insertion Site Integration." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307106075.

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Books on the topic "Tendon healing"

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Society for the Study of Native Arts and Sciences., ed. Tendon and ligament healing: A new approach through manual therapy. Berkeley, Calif: North Atlantic Books, 1999.

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Barber, Victoria Lynette. An evaluation of tendon healing using magnetic resonance imaging and a standard physical assessment. [New Haven: s.n.], 1990.

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Kusler, Ruth Weil. Tender hands: Ruth's story of healing. Fargo: Germans from Russia Heritage Collection, North Dakota State University Libraries, 1998.

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The tender touch of God. Eugene, Or: Harvest House Publishers, 1996.

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Tending inner gardens: The healing art of feminist psychotherapy. New York: Haworth Press, 1995.

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Healing the ravaged soul: Tending the spiritual wounds of child sexual abuse. U.K: Lutterworth Press, 2016.

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Barry, Parker. Memorial: A ministry of healing. Chattanooga, TN: Parker Hood Press, 1997.

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Salter, Robert Bruce. Continuous passive motion (CPM): A biological concept for the healing and regeneration of articular cartilage, ligaments, and tendons : from origination to research to clinical applications. Baltimore: Williams & Wilkins, 1993.

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Harrison, Mark. Wound healing. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198765875.003.0057.

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This chapter describes the pathology of wound healing as it applies to Emergency Medicine, and in particular the Primary FRCEM examination. The chapter outlines the key details of haemostasis, inflammation, reconstruction, epithelialization, and maturation, and the specific tissues affected, including skin, tendon, peripheral nerve, bone, myocardium, and brain. This chapter is laid out exactly following the RCEM syllabus, to allow easy reference and consolidation of learning.
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Weintraub, William. Tendon and Ligament Healing. A new approach through manual therapy. Thieme, Stuttgart, 2001.

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Book chapters on the topic "Tendon healing"

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Pauyo, Thierry, Elmar Herbst, and Freddie H. Fu. "Tendon Healing." In Muscle and Tendon Injuries, 45–50. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54184-5_4.

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Löhr, J. F., Hirotaka Sano, and H. K. Uhthoff. "Rotator Cuff Tendon Healing." In Schulterinstabilität — Rotatorenmanschette, 202–5. Heidelberg: Steinkopff, 1999. http://dx.doi.org/10.1007/978-3-642-58711-5_18.

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Oliva, Francesco, Stefano Gatti, Giuseppe Porcellini, Nicholas R. Forsyth, and Nicola Maffulli. "Growth Factors and Tendon Healing." In Rotator Cuff Tear, 53–64. Basel: KARGER, 2011. http://dx.doi.org/10.1159/000328878.

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Bisciotti, Gian Nicola, and Piero Volpi. "Healing Processes of the Tendon." In The Lower Limb Tendinopathies, 21–40. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33234-5_2.

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Volpi, Piero, and Gian Nicola Bisciotti. "Healing Processes in Tendon Tissue." In Muscle Injury in the Athlete, 53–72. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16158-3_3.

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Ackermann, Paul W. "Biologics in Tendon Healing: PRP/Fibrin/Stem Cells." In The Achilles Tendon, 135–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54074-9_23.

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Vogel, Laura A., Andreas Voss, and Augustus D. Mazzocca. "Healing of the Rotator Cuff Tendon." In Rotator Cuff Across the Life Span, 19–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-58729-4_3.

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Ahmed, Aisha Siddiqah. "Does Diabetes Mellitus Affect Tendon Healing?" In Metabolic Influences on Risk for Tendon Disorders, 179–84. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33943-6_16.

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Domeij-Arverud, Erica, and Paul W. Ackermann. "Deep Venous Thrombosis and Tendon Healing." In Metabolic Influences on Risk for Tendon Disorders, 221–28. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33943-6_21.

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Akintunde, Akinjide R., Daniele E. Schiavazzi, and Kristin S. Miller. "Mathematical Model of Age-Specific Tendon Healing." In Lecture Notes in Computational Vision and Biomechanics, 288–96. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-43195-2_23.

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Conference papers on the topic "Tendon healing"

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Carvalho, P. T. C., Cheila O. C. Batista, and C. Fabíola. "Low level laser therapy in healing tendon." In Laser Florence 2004, edited by Leonardo Longo, Khalil A. Khatri, Mihail-Lucian Pascu, and Wilhelm R. Waidelich. SPIE, 2005. http://dx.doi.org/10.1117/12.660046.

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Gilday, Steven D., Chris Casstevens, Jason T. Shearn, and David L. Butler. "Analysis of Regional Strain Patterns Following Surgical Disruption of the Enthesis in a Murine Model of Patellar Tendon Injury." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14569.

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Tendon injuries are common yet often fail to heal naturally, especially in cases in which the native tendon-to-bone insertion site is disrupted. Surgical tendon repairs are often limited by the inability of the ruptured tendon to functionally attach back to the underlying bone. For patients with tendon injuries, poor tendon-to-bone integration prolongs recovery time and increases the risk of re-rupture. Improvements in tendon repair will require a more complete understanding of both the biological and mechanical phenomena that occur during natural tendon-to-bone healing. Mechanical studies of
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Riggin, Corinne N., Joseph J. Sarver, Benjamin R. Freedman, Stephen J. Thomas, and Louis J. Soslowsky. "Analysis of Collagen Fiber Organization in Mouse Achilles Tendon Using High-Frequency Ultrasound Imaging." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14472.

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Achilles tendon ruptures are traumatic injuries that frequently occur in active individuals and result in significant medical expense. Common techniques for assessing outcomes of surgical repair and rehabilitation rely heavily on patient-based measures of pain and function. While these measures can provide evidence for recovery of functional performance, they do not directly assess tendon healing which, if insufficient, can lead to re-rupture. The clinical evaluation of collagen organization following Achilles tendon injury may provide a more accurate measure of healing than traditional, funct
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Dyment, Nathaniel A., Namdar Kazemi, Lindsey E. Aschbacher-Smith, Nicolas J. Barthelery, Keith Kenter, Cynthia Gooch, Jason T. Shearn, Christopher Wylie, and David L. Butler. "The Relationships Among Spatiotemporal Gene Expression, Histology, and Biomechanics Following Full-Length Injury in the Murine Patellar Tendon." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53622.

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Tendon and ligament injuries present a considerable socioeconomic impact as close to 50% of the 32 million musculoskeletal injuries in the US per year include these structures [1]. The inadequate healing in these tissues requires novel treatment modalities. Improving tendon tissue engineering dictates that we better understand the process of natural adult tendon healing. Type-I (Col1) and Type-II (Col2) collagens are important structural proteins in tendon as Col1 is the main collagen type found in the tendon midsubstance while Col2 is expressed at the insertion into bone during development, g
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Abramowitch, Steven D., Matthew B. Fisher, Sinan Karaoglu, and Savio L. Y. Woo. "The Mechanical and Viscoelastic Properties of the Healing Rabbit Patellar Tendon." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176183.

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Central third bone-patellar tendon-bone (BPTB) autografts are commonly used for anterior cruciate ligament (ACL) reconstructions. Following surgery, complications arise at the donor site, including extension deficits and anterior knee pain [1]. These complications are partially caused by inadequate healing of the patellar tendon (PT) as well as adhesions in the anterior interval. Recent clinical data have suggested these are contributing factors in the early development of osteoarthrosis following ACL reconstruction [2]. Thus, it is necessary to understand the changes in mechanical and viscoel
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Ansorge, H. L., J. E. Hsu, L. Edelstein, D. E. Birk, and L. J. Soslowsky. "Injury During Early Neonatal Development Leads to a Faster Repair Response When Compared to Later Injury in a Mouse Achilles Tendon." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19232.

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During neonatal development, tendons undergo a well orchestrated process whereby extensive structural and compositional changes occur in synchrony to produce a normal tissue [1,2]. Similarly, during the repair response to injury, structural and compositional changes occur, but in this case, a mechanically inferior tendon is produced. As a result, the process of development has been postulated as a potential paradigm through which improved tissue healing may occur. By examining injury at distinctly different stages of development, we will obtain vital information into the structure-function rel
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Thomopoulos, S., R. Das, H. M. Kim, D. Zeltser, K. Kousari, and L. Galatz. "The Role of the Loading Environment on the Developing Tendon-to-Bone Insertion." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206837.

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A transition zone forms at the attachment of tendon to bone during post-natal development [1]. We previously showed that this transitional tissue reduces stress concentrations at the insertion and hence reduces the risk for failure [2]. During tendon-to-bone healing, on the other hand, a transition zone does not develop at the interface [3]. Unlike development, inferior scar tissue fills the repair site and the repair is prone to rupture at the attachment. Understanding the development of the insertion will allow us to develop solutions to augment tendon-to-bone healing.
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Komolafe, Oluseeni A., and Todd C. Doehring. "Nonlinear Elastic Behavior of Achilles Tendon at the Fascicle Scale." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176880.

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Parallel collagen fibers such as ligaments and tendons are composed of fiber bundles, or fascicles, enclosed in a sheath of reticular membrane. In the Achilles tendon, these fascicles can be long, extending from the gastro-soleus unit to the calcaneal insertion site (Fig. 1). Although the overall functional behavior of the whole tendon is well established[1], there is little information detailing properties of individual fascicles or their interactions. Knowledge of the structural and biomechanical properties at the “mesostructural” scale (i.e. fascicle-scale) is critical to understanding tiss
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Chokalingam, Kumar, Chris Frede, Jane L. Florer, Richard J. Wenstrup, and David L. Butler. "Col1 and Col2 Gene Expression During the Development of Murine Knee Joints." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192596.

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Recently, tissue engineers have turned to developmental biology to try and improve the repair of tendons and ligaments [1]. The premise is that understanding normal growth and development of tendons and ligaments might facilitate in later repair. Understanding these similarities in extracellular matrix gene expression and growth factor expression might allow tissue engineers to develop treatments to augment adult tendon and ligament healing.
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Thomopoulos, Stavros, Alistair Kent, Victor Birman, Rosalina Das, Brigitte Wopenka, Jill Pasteris, and Guy Genin. "Mineral Composition at the Tendon-to-Bone Insertion and Its Role in Stress Transfer." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176387.

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Musculoskeletal injuries are a common cause of pain and disability, and result in significant health care costs. Rotator cuff injuries, which make up the majority of soft tissue injuries to the upper extremity, commonly require surgical repair to the humeral head. At the rotator cuff, for example, the recurrence of tears to surgically repaired tendons has been reported to be as high as 94% [1]. The most dramatic feature of the failed tendon-to-bone healing scenarios is the lack of a transition zone between the tendon and bone that existed before the injury [2].
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