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1

Walach, H., W. Haeusler, T. Lowes, D. Mussbach, U. Schamell, W. Springer, G. Stritzl, W. Gaus, and G. Haag. "Classical Homeopathic Treatment of Chronic Headaches." Cephalalgia 17, no. 2 (April 1997): 119–26. http://dx.doi.org/10.1046/j.1468-2982.1997.1702119.x.

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We conducted a randomized, placebo-cor rolled, double-blind clinical trial in order to determine the efficacy of classical homeopathic therapy in patients with chronic headaches. After 6 weeks of baseline observation, patients received either the prescribed individualized homeopathic medication or an indistinguishable placebo for 12 weeks. Outcome parameters were headache frequency, duration, and intensity, measured daily by diary. Use of medication for acure headache was also monitored. Of the 98 patients in the sample, 37 were randomized to receive placebo, 6I received individualized homeopathic remedies. Groups were comparable at the beginning of the treatment. The median age was 48.5 years; 76% suffered from migraine, 51% from tension-type headaches, and 94% were previously treated for headache. The median headache frequency was 3 days a week. Headaches were present for 23 years (median). In both groups, patients showed an improvement of one headache day less per month. The use of medication for acute headache was reduced. The headache frequency of 11 patients was reduced by more than 40%. Thirty-nine patients either did not improve or experienced aggravations. There was no significant difference in any parameter between homeopathy and placebo.
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2

Muscari-Tomaioli, G., F. Allegri, E. Miali, R. Pomposelli, P. Tubia, A. Targhetta, M. Castellini, and P. Bellavite. "Observational study of quality of life in patients with headache, receiving homeopathic treatment." British Homeopathic Journal 90, no. 04 (October 2001): 189–97. http://dx.doi.org/10.1054/homp.1999.0511.

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AbstractThis study describes the results obtained from a prospective observational research of homeopathic treatment for patients suffering from headache (migraine with- and without aura and tension-type headache). Fifty-three patients were asked to complete the SF-36 questionnaire at the beginning of the treatment and after 4–6 months. The homeopathic medicine and potency were not pre-defined, but were adapted to each single patient according to individualised homeopathic prescription. Most patients (73.6%) completed the study. There was heterogeneity in the answers (patients in very poor health as well as those with only slight disorders). Analysis of the data according to the concept of ‘intention-to-treat’ showed that after therapy, the mean and median scores of all life quality dimensions rose. More than 60% of the cases experienced an improvement in pain and the limitations caused by pain, as well as in limitations in social activities and health in general. All the differences between pre/post treatment were statistically highly significant, with the strongest results in the ‘bodily pain’ and ‘vitality’ parameters (P<0.0001).
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3

Vithoulkas, G. "Homeopathic treatment of chronic headache: a critique." Homeopathy 91, no. 1 (January 2002): 32–34. http://dx.doi.org/10.1054/homp.2001.0012.

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4

Kotova, Olga V., Аnton А. Belyaev, and Elena S. Akarachkova. "Tension headache: clinic, diagnosis, treatment." Consilium Medicum 22, no. 9 (2020): 68–70. http://dx.doi.org/10.26442/20751753.2020.9.200458.

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Головная боль напряжения (ГБН) – это неврологическое расстройство, характеризующееся приступами легкой или умеренной головной боли с не-большим количеством сопутствующих симптомов. Распространенность ГБН у взрослых в течение жизни, по результатам 5 популяционных иссле-дований, составляет 46% (диапазон 12–78%). Основная причина ГБН неизвестна. Диагноз ставится на основании анамнеза и обследования. Многие пациенты самостоятельно лечат острые приступы и обращаются за медицинской помощью, когда приступы становятся частыми или хроническими. В лечении ГБН рекомендуют поведенческую терапию, купирование болевых эпизодов и профилактическое лечение. Острые приступы ГБН обычно купируют простыми анальгетиками (парацетамол, ацетилсалициловая кислота) или нестероидными противовоспалительными препаратами [ибу-профен, кетопрофен, напроксен]. Ситуация с обезболиванием при ГБН изменилась при появлении быстродействующих форм нестероидных проти-вовоспалительных препаратов, в частности ибупрофена, так как быстроабсорбирующиеся соли ибупрофена действуют достоверно быстрее, имеют более выраженный и пролонгированный анальгетический эффект. Ключевые слова: головная боль напряжения, эпидемиология, клиника, диагностика, лечение, быстродействующие формы ибупрофена. Для цитирования: Котова О.В., Беляев А.А., Акарачкова Е.С. Головная боль напряжения: клиника, диагностика, лечение. Consilium Medicum. 2020; 22 (9): 68–70. DOI: 10.26442/20751753.2020.9.200458
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5

Frediani, F., L. Grazzi, B. Zappacosta, A. Boiardi, and G. Bussone. "Biofeedback Treatment For Tension Headache." Cephalalgia 7, no. 6_suppl (September 1987): 497–98. http://dx.doi.org/10.1177/03331024870070s6224.

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6

Bogaards, Moniek C., and Moniek M. ter Kuile. "Treatment of Recurrent Tension Headache." Clinical Journal of Pain 10, no. 3 (September 1994): 174–90. http://dx.doi.org/10.1097/00002508-199409000-00003.

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7

Millichap, J. Gordon. "Behavioral Treatment for Tension-Type Headache." Pediatric Neurology Briefs 17, no. 4 (April 1, 2003): 31. http://dx.doi.org/10.15844/pedneurbriefs-17-4-7.

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8

Ashina, Messoud, Med Sci, and Sait Ashina. "Tension-type headache." NATIONAL JOURNAL OF NEUROLOGY, no. 1 (January 15, 2019): 10–19. http://dx.doi.org/10.28942/nnj.v1i1.208.

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Tension-type headache is the most common primary headache disorder. The life-time prevalence of tension-type headache in general population is between 30 to 78%. Tension-type has the tremendous socio-economic impact on the individual and the society. Unfortunately, it is the least studied primary headache. The pathophysiology of this headache disorder is not fully understood. The diagnosis of tension-type headache is based on the history, and general and neurological examinations. Abnormalities in peripheral and central nociceptive nervous systems in combination with environmental and genetic factors may play a role in the pathophysiology of tension-type headache. The pharmacotherapy of episodic tension-type headache is non-specific and includes simple analgesics and nonsteroidal anti-inflammatory drugs. Tricyclic antidepressants are the mainstay in the prophylactic treatment of chronic tension-type headache.
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9

Colas, Aurélie, Laurence Terzan, Marie-France Bordet, and Karine Danno. "Homeopathic treatment of premenstrual syndrome: a case series." Homeopathy 102, no. 01 (January 2013): 59–65. http://dx.doi.org/10.1016/j.homp.2012.10.004.

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Objective: Observational, prospective study to describe the homeopathic management of premenstrual syndrome (PMS) by a group of French physicians.Method: Women with PMS for >3 months were prescribed individualized homeopathic treatment. The intensity of 10 clinical symptoms of PMS was scored individually at inclusion and at a 3–6 month follow-up visit: absent = 0, mild = 1, moderate = 2, severe = 3. Total symptom score (range: 0–30) was calculated and compared for each patient at inclusion and at follow-up. PMS impact on daily activities (quality of life, QoL) was compared at inclusion and follow-up as: none, mild, moderate, severe, very severe.Results: Twenty-three women were prescribed homeopathic treatment only (mean age: 39.7 years). Folliculinum (87%) was the most frequently prescribed homeopathic medicine followed by Lachesis mutus (52.2%). The most common PMS symptoms (moderate or severe) at inclusion were: irritability, aggression and tension (87%), mastodynia (78.2%) and weight gain and abdominal bloating (73.9%); and the most common symptoms at follow-up were: irritability, aggression and tension (39.1%), weight gain and abdominal bloating (26.1%) and mastodynia (17.4%). Mean global score for symptom intensity was 13.7 at inclusion and 6.3 at follow-up. The mean decrease in score (7.4) was statistically significant (p < 0.0001). Twenty-one women reported that their QoL also improved significantly (91.3%; p < 0.0001).Conclusions: Homeopathic treatment was well tolerated and seemed to have a positive impact on PMS symptoms. Folliculinum was the most frequent homeopathic medicine prescribed. There appears to be scope for a properly designed, randomized, placebo-controlled trial to investigate the efficacy of individual homeopathic medicines in PMS.
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10

Rosa, Buontempo, Addamo Pietro, and Visconti Rosella. "Acupuncture in tension headache treatment: a treatment protocol." European Journal of Integrative Medicine 4 (September 2012): 135. http://dx.doi.org/10.1016/j.eujim.2012.07.787.

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11

Tulunay, F. Cankat, Onur Karan, Nursel Aydin, and Adrian Guvener. "Treatment of Tension Headache by Vibratory Stimulation." Cephalalgia 5, no. 3_suppl (July 1985): 122–23. http://dx.doi.org/10.1177/03331024850050s342.

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12

Schneider, Udo, Dominique Rada, Jens D. Rollnik, Thorsten Passie, and Hinderk M. Emrich. "Propofol dependency after treatment of tension headache." Addiction Biology 6, no. 3 (July 2001): 263–65. http://dx.doi.org/10.1080/13556210120056607.

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13

Ziegler, D. K. "Tension-Type Headache: Classification, Mechanisms, and Treatment." Archives of Neurology 52, no. 3 (March 1, 1995): 235. http://dx.doi.org/10.1001/archneur.1995.00540270023011.

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14

Kunkel, Robert S. "Tension-type headache: Classification, mechanisms, and treatment." Journal of Pain and Symptom Management 9, no. 5 (July 1994): 352–53. http://dx.doi.org/10.1016/0885-3924(94)90196-1.

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15

Kahriman, Azmin, and Shuhan Zhu. "Migraine and Tension-Type Headache." Seminars in Neurology 38, no. 06 (December 2018): 608–18. http://dx.doi.org/10.1055/s-0038-1673683.

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AbstractMigraine and tension-type headache (TTH) are common primary disorders that carry significant morbidity and socioeconomic effect. In this article, we will review the epidemiology, presentation, and diagnosis of these disorders. First-line acute treatment for migraine consists of analgesics, triptans, and antiemetics, while nonsteroidal anti-inflammatory drugs are the mainstay treatment for TTH. Patients with frequent or chronic headaches warrant prophylactic therapy. For migraine, various classes of preventives can be used (β-blockers, tricyclics, antiepileptics, botulinum toxin), with the choice of therapy tailored to the patient's risk factors and symptoms. For TTH, tricyclics have the most evidence as prophylactic therapy. A new class of medication, monoclonal antibodies to calcitonin gene receptor peptide or its receptor, became available in 2018, and is the first class of medication specifically designed to treat migraine. In addition to pharmacotherapy, we will also review nonpharmacologic interventions as well as neuromodulation for migraine.
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16

Astashina, N. B., N. L. Starikova, and K. R. Valiakhmetova. "Modern view on the problem of splint therapy in treatment of chronic tension type headache." Perm Medical Journal 38, no. 3 (July 16, 2021): 61–67. http://dx.doi.org/10.17816/pmj38361-67.

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The review presents the epidemiology of tension type headache. The key points of etiology, pathogenesis and clinical picture are described, modern therapeutic approaches to the treatment of chronic tension headache are considered. The data on the possibility of using prosthetic and splint therapy for correction of health status in patients with chronic tension type headache are presented. The necessity of conducting research aimed at determining the role of using occlusive splints and the significance of correcting occlusive relationships in chronic tension type headache is grounded.
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17

Lee, Elaine, Sean Moloney, Joel Talsma, and Stacey Pierce-Talsma. "Osteopathic Manipulative Treatment Considerations in Tension-Type Headache." Journal of the American Osteopathic Association 119, no. 10 (October 1, 2019): e40. http://dx.doi.org/10.7556/jaoa.2019.096.

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18

ChongNak Son. "Biofeedback in the Treatment of Tension-type Headache." Korean Journal of Health Psychology 14, no. 4 (December 2009): 729–42. http://dx.doi.org/10.17315/kjhp.2009.14.4.003.

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19

Tulunay, F. Cankat, O. Karan, and A. GÜVener. "Treatment Of Tension Headache By Low Dose Mianserin." Cephalalgia 7, no. 6_suppl (September 1987): 491–92. http://dx.doi.org/10.1177/03331024870070s6221.

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20

Smitherman, Todd A., Robert A. Nicholson, and Donald B. Penzien. "Osteopathic Treatment Versus “Relaxation” for Tension-Type Headache." Headache: The Journal of Head and Face Pain 47, no. 3 (March 19, 2007): 450–51. http://dx.doi.org/10.1111/j.1526-4610.2007.00739.x.

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21

Biondi, Massimo, and Giovanni Portuesi. "Tension-Type Headache: Psychosomatic Clinical Assessment and Treatment." Psychotherapy and Psychosomatics 61, no. 1-2 (1994): 41–64. http://dx.doi.org/10.1159/000288870.

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22

Tucker, Tarvez. "A Practical Approach to Headache Treatment." Journal of Pharmacy Practice 20, no. 2 (April 2007): 123–36. http://dx.doi.org/10.1177/0897190007305133.

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The World Health Organization cites migraine headache as one of the 20 most disabling medical conditions. This article focuses on the diagnosis and treatment of the primary headache disorders, with special emphasis on migraine, the headache most likely to bring patients to physicians and pharmacists. This review begins with the warning signs of the ominous headache, which, although rare, can herald a life-threatening condition. Clinical characteristics of the primary headache types, migraine, tension-type headache, and cluster headache, are described. Although many individuals believe their headaches are “sinus,” or “stress or tension-induced,” most of the characteristics of these types of headaches actually meet International Headache Society criteria for migraine. Treatments of primary headaches, including acute therapies, abortive agents, and prophylactic medications, are uniquely specific for each headache syndrome. Chronic daily headache patients compose only 4% of the population yet make up the largest percentage of patients who seek treatment at specialty headache centers. Medication-overuse headache, the syndrome in which medications taken for the relief of headache actually foster future headaches, offers a particular challenge to health care providers, as does narcotic use in headache therapy. Complementary and alternative treatments proven efficacious in the treatment of primary headache are also described.
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23

Padberg, M., SFTM de Bruijn, RJ de Haan, and DLJ Tavy. "Treatment of Chronic Tension-Type Headache with Botulinum Toxin: A Double-Blind, Placebo-Controlled Clinical Trial." Cephalalgia 24, no. 8 (August 2004): 675–80. http://dx.doi.org/10.1111/j.1468-2982.2004.00738.x.

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Botulinum toxin is increasingly advocated as effective treatment in chronic tension-type headache. We conducted a randomized, placebo-controlled clinical trial to prove efficacy of botulinum toxin in chronic tension-type headache. Patients were randomly assigned to receive botulinum toxin (maximum 100 units) or placebo (saline) in muscles with increased tenderness. After 12 weeks there was no significant difference between the two treatment groups in decrease of headache intensity on VAS (-3.5 mm, 95% confidence interval (CI) -20 to +13), mean number of headache days (-7%; 95% CI -20 to +4), headache hours per day (-1.4%; 95% CI -3.9 to +1.1), days on which symptomatic treatment was taken (-1.9%; 95% CI -11 to +7) and number of analgesics taken per day (-0.01; 95% CI -0.25-0.22). There was no significant difference in patient's assessment of improvement after week 4, 8 and 12. Botulinum toxin was not proven effective in treatment of chronic tension-type headache. Increased muscle tenderness might not be as important in pathophysiology of chronic tension-type headache as hitherto believed.
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24

Kopchak, O. O. "Tension-type headache and cervicogenic headache: peculiarities of clinical picture, diagnosis and treatment." INTERNATIONAL NEUROLOGICAL JOURNAL, no. 3.105 (June 23, 2019): 52–57. http://dx.doi.org/10.22141/2224-0713.3.105.2019.169919.

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25

Chesser, M. "Tension-Type Headache: Classification, Mechanisms, and Treatment (Frontiers in Headache Research, Vol. 3)." Neurology 44, no. 3, Part 1 (March 1, 1994): 590. http://dx.doi.org/10.1212/wnl.44.3_part_1.590-b.

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26

Shypilova, E. M., N. N. Zavadenko, and Yu E. Nesterovskiy. "Preventive treatment of tension headache in children and adolescents." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 117, no. 7 (2017): 36. http://dx.doi.org/10.17116/jnevro20171177136-42.

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27

Amelin, A. V., L. E. Babayan, M. I. Myatleva, S. V. Tarasova, and B. Ch Tumelevich. "New perspectives for the treatment of tension-type headache." Consilium Medicum 17, no. 9 (2015): 79–81. http://dx.doi.org/10.26442/2075-1753_2015.9.79-81.

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28

Jensen, Rigmor, and Jes Olesen. "Tension-type headache: an update on mechanisms and treatment." Current Opinion in Neurology 13, no. 3 (June 2000): 285–89. http://dx.doi.org/10.1097/00019052-200006000-00009.

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29

Lohman, J. J. H. M. "Book Review: Tension-Type Headache: Classification, Mechanisms, and Treatment." Annals of Pharmacotherapy 28, no. 10 (October 1994): 1205. http://dx.doi.org/10.1177/106002809402801024.

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30

Bendtsen, Lars. "Review: Drug and nondrug treatment in tension-type headache." Therapeutic Advances in Neurological Disorders 2, no. 3 (April 30, 2009): 155–61. http://dx.doi.org/10.1177/1756285609102328.

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31

Vuković, Vlasta, Davor Plavec, Arijana Lovrenčić Huzjan, Mislav Budišić, and Vida Demarin. "Treatment of migraine and tension-type headache in Croatia." Journal of Headache and Pain 11, no. 3 (March 6, 2010): 227–34. http://dx.doi.org/10.1007/s10194-010-0200-9.

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32

Tabeeva, Guzyal' Rafkatovna, Yu E. Azimova, Guzyal Rafkatovna Tabeyeva, and Yu E. Azimova. "Novelty in the treatment of episodic tension-type headache." Neurology, neuropsychiatry, Psychosomatics, no. 4 (December 15, 2010): 57. http://dx.doi.org/10.14412/2074-2711-2010-118.

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33

Bigal, Marcelo E., Alan M. Rapoport, and Richard Hargreaves. "Advances in the pharmacologic treatment of tension-type headache." Current Pain and Headache Reports 12, no. 6 (November 25, 2008): 442–46. http://dx.doi.org/10.1007/s11916-008-0075-5.

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34

Ahmadi, Alireza, David C. Schwebel, and Mansour Rezaei. "The Efficacy of Wet-Cupping in the Treatment of Tension and Migraine Headache." American Journal of Chinese Medicine 36, no. 01 (January 2008): 37–44. http://dx.doi.org/10.1142/s0192415x08005564.

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Wet-cupping is an ancient medical technique still used in several contemporary societies, but little empirical study has been devoted to test its efficacy to treat tension and migraine headache. Using a pre-post research design, 70 patients with chronic tension or migraine headache were treated with wet-cupping. Three primary outcome measures were considered at the baseline and 3 months following treatment: headache severity, days of headache per month, and use of medication. Results suggest that, compared to the baseline, mean headache severity decreased by 66% following wet-cupping treatment. Treated patients also experienced the equivalent of 12.6 fewer days of headache per month. We conclude that wet-cupping leads to clinical relevant benefits for primary care patients with headache. Possible mechanisms of wet-cupping's efficacy, as well as directions for future research are discussed.
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35

Seshia, Shashi S., Ishaq Abu-Arafeh, and Andrew D. Hershey. "Tension-Type Headache in Children: The Cinderella of Headache Disorders!" Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 36, no. 6 (November 2009): 687–95. http://dx.doi.org/10.1017/s0317167100008295.

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Tension-type headache (TTH) may be as common a headache disorder as migraine in children and adolescents. TTH has a neurobiological basis with genetic and environmental factors making variable contributions to the different sub-types. The diagnostic criteria for TTH in the second edition of the “International Classification of Headache Disorders” appear to be applicable to children. Anxiety and mood disorders may be co-morbid with frequent episodic and chronic TTH. Psychosocial stressors play an important role in precipitating and maintaining TTH. Hence, a biopsychosocial approach should be adopted for care. Standardized histories and examinations together with prospective headache diaries are the foundations for good management; attention to ‘red flags’ will help identify secondary causes that present with headache similar to TT. There are no randomized controlled drug trials for the treatment of TTH. Relaxation and cognitive behavioral therapies are effective. TTH in children and adolescents warrants greater recognition from the clinician and scientist. Studies focusing on TTH are overdue.
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36

Dahlof, CGH, and LD Jacobs. "Ketoprofen, Paracetamol and Placebo in the Treatment of Episodic Tension-Type Headache." Cephalalgia 16, no. 2 (April 1996): 117–23. http://dx.doi.org/10.1046/j.1468-2982.1996.1602117.x.

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The aim of the study was to assess the efficacy and tolerability of a single oral dose of ketoprofen 25 mg in comparison with single doses of ketoprofen 2 × 25 mg, paracetamol 500 mg and 1,000 mg, and placebo in the treatment of episodic tension-type headache. The study was conducted as a single centre, double-blind, randomized, placebo-controlled, five-period, within-patient comparative trial in outpatients with episodic tension-type headache according; to the International Headache Society's diagnostic criteria. Each patient had to treat five attacks of episodic tension-type headache with a single dose of each of the tested medications with a minimum interval o 72 h between two attacks. Details of the attack and response to treatment were recorded on a diary card Altogether 30 patients treated 5 attacks and 2, 3, 1 and 4 patients treated 4, 3, 2 and 1 attack, respectively, The primary variable was decrease in headache pain intensity from baseline to 2 h after intake, evaluated by means of a 100 mm visual analogue scale. Ketoprofen 50 mg was significantly better than placebo an paracetamol for this main criterion. Neither of the paracetamol groups differed from the placebo group, Only a few adverse events were reported, usually of mild or moderate severity, with no difference between the treatments. Ketoprofen 50 mg may be considered an effective and well tolerated analgesic in the treatment of episodic tension-type headache of moderate or severe intensity.
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37

Bendtsen, L., ME Bigal, R. Cerbo, HC Diener, K. Holroyd, C. Lampl, DD Mitsikostas, TJ Steiner, and P. Tfelt-Hansen. "Guidelines for Controlled Trials of Drugs in Tension-Type Headache: Second Edition." Cephalalgia 30, no. 1 (August 1, 2009): 1–16. http://dx.doi.org/10.1111/j.1468-2982.2009.01948.x.

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The Clinical Trials Subcommittee of the International Headache Society published its first edition of the guidelines on controlled trials of drugs in tension-type headache in 1995. These aimed ‘to improve the quality of controlled clinical trials in tension-type headache’, because ‘good quality controlled trials are the only way to convincingly demonstrate the efficacy of a drug, and form the basis for international agreement on drug therapy’. The Committee published similar guidelines for clinical trials in migraine and cluster headache. Since 1995 several studies on the treatment of episodic and chronic tension-type headache have been published, providing new information on trial methodology for this disorder. Furthermore, the classification of the headaches, including tension-type headache, has been revised. These developments support the need for also revising the guidelines for drug treatments in tension-type headache. These Guidelines are intended to assist in the design of well-controlled clinical trials in tension-type headache.
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38

Leira, Rogelio, Josè Castillo, Francisco Martinez, Josè Maria Prieto, and Manuel Noya. "Platelet-Rich Plasma Serotonin Levels in Tension-Type Headache and Depression." Cephalalgia 13, no. 5 (October 1993): 346–48. http://dx.doi.org/10.1046/j.1468-2982.1993.1305346.x.

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We measured platelet-rich plasma (PRP) serotonin in patients suffering from tension-type headache, before and after treatment with amitriptyline, comparing them with a healthy control group and patients with untreated depression. We evaluated the severity of headache and depression in each group. PRP serotonin levels were higher in patients with headache than in controls and depressed patients. We observed a fall of PRP serotonin in patients with tension-type headache to similar levels after treatment as the depressed group. This fall was correlated with the improvement of headache but not with depression scales. Our data suggest that the rise of platelet serotonin levels in tension-type headache is related to pain and not depression.
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39

Ashina, Håkan, Afrim Iljazi, Haidar Muhsen Al-Khazali, Sait Ashina, Rigmor Højland Jensen, Faisal Mohammad Amin, Messoud Ashina, and Henrik Winther Schytz. "Persistent post-traumatic headache attributed to mild traumatic brain injury: Deep phenotyping and treatment patterns." Cephalalgia 40, no. 6 (February 26, 2020): 554–64. http://dx.doi.org/10.1177/0333102420909865.

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Objective To investigate clinical characteristics and treatment patterns in persistent post-traumatic headache attributed to mild traumatic brain injury. Methods A total of 100 individuals with persistent post-traumatic headache attributed to mild traumatic brain injury were enrolled between July 2018 and June 2019. Deep phenotyping was performed using a semi-structured interview while allodynia was assessed using the 12-item Allodynia Symptom Checklist. Results In 100 subjects with persistent post-traumatic headache, the mean headache frequency was 25.4 ± 7.1 days per month. The most common headache phenotype was chronic migraine-like headache (n = 61) followed by combined episodic migraine-like and tension-type-like headache (n = 29) while nine subjects reported “pure” chronic tension-type-like headache. The most frequent trigger factors were stress, lack of sleep, and bright lights. A history of preventive medication use was reported by 63 subjects, of which 79% reported failure of at least one preventive drug, while 19% reported failure of at least four preventive drugs. Cutaneous allodynia was absent in 54% of the subjects, mild in 23%, moderate in 17%, and severe in 6%. Conclusions The headache profile of individuals with persistent post-traumatic headache most often resembled a chronic migraine-like phenotype or a combined episodic migraine-like and tension-type-like headache phenotype. Migraine-specific preventive medications were largely reported to be ineffective. Therefore, there is a pressing need for pathophysiological insights and disease-specific therapies.
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Carlsson, Jane, Astrid Fahlcrantz, and Lars-Erik Augustinsson. "Muscle Tenderness in Tension Headache Treated with Acupuncture or Physiotherapy." Cephalalgia 10, no. 3 (June 1990): 131–41. http://dx.doi.org/10.1046/j.1468-2982.1990.1003131.x.

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Sixty-two female patients with chronic tension headache were randomized into two treatment groups-acupuncture and physiotherapy. The intensity of headache, muscle tenderness and neck mobility was assessed before and after treatment. Thirty healthy women were used for comparison. Before treatment it was found that muscle tenderness was increased and neck rotation was reduced in the patient group compared with controls. There was a significant correlation between the intensity of headache and muscle tenderness. After treatment, the intensity of headache and muscle tenderness were reduced in both treatment groups. The headache was more improved in the physiotherapy group, and there was a marked reduction in the intake of analgesics. The tenderness was reduced in all muscles tested in the physiotherapy group but only in some of the muscles after acupuncture. The limitation of neck rotation was not influenced by either treatment.
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Delva, M. Yu, and I. I. Delva. "SOCIO-DEMOGRAPHIC AND COMORBID CHARACTERISTICS OF PATIENTS WITH TENSION HEADACHE." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 21, no. 1 (March 21, 2021): 16–20. http://dx.doi.org/10.31718/2077-1096.21.1.16.

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Introduction. Chronic tension headache is a significant medical and social challenge. There are many factors, which interact resulting in the chronicity of tension headache. The aim of the study was to investigate social, demographic and comorbid characteristics of the patients with frequent episodic tension headache and chronic tension headache. Material and methods. We examined 93 patients with frequent episodic tension headache and 34 patients with chronic tension headache. We analyzed patients’ sex, age, marital status, educational level, employment, smoking habits, anxiety and depressive disorders (according to the Hospital Anxiety and Depression Scale), migraine, musculoskeletal pains (cervical and lower back), arterial hypertension, diabetes mellitus, abdominal obesity, and history of traumatic brain injury. Results. The patients with chronic tension headache in comparison with the patients having frequent episodic tension headache had significantly more common (p <0.05) having no family (47% vs. 23%), smokers (35% vs. 16%), had significantly more common anxiety disorders (82% vs. 27%), depressive disorders (79% vs. 27%), abdominal obesity (41% vs. 13%) and episodes of lower back pain during the last calendar year (53% vs. 22%). Conclusions. Timely identification and adequate correction of lifestyle and some conditions (smoking, anxiety and depressive disorders, abdominal obesity) as well as pathogenetically grounded treatment of lower back pain in the patients with frequent episodic tension headache may reduce the risk of headache chonicity.
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Levy, Dan, Hila Gruener, Miri Riabinin, Yelena Feingold, Shaul Schreiber, Chaim G. Pick, and Ruth Defrin. "Different clinical phenotypes of persistent post-traumatic headache exhibit distinct sensory profiles." Cephalalgia 40, no. 7 (December 17, 2019): 675–88. http://dx.doi.org/10.1177/0333102419896368.

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Introduction Persistent post-traumatic headache remains a poorly understood clinical entity. Although there are currently no accepted therapies for persistent post-traumatic headache, its clinical symptoms, which primarily resemble those of migraine or tension-type headache, often serve to guide treatment. However, evidence-based justification for this treatment approach remains lacking given the paucity of knowledge regarding the characteristics of these two major persistent post-traumatic headache phenotypes and their etiology. Methods We compared clinical features and quantitative sensory testing profiles between two distinct cohorts of persistent post-traumatic headache subjects that exhibited symptoms resembling either migraine (n = 15) or tension-type headache (n = 13), as well as to headache-free subjects that had suffered traumatic brain injury (n = 19), and to healthy controls (n = 10). We aimed to determine whether the two persistent post-traumatic headache subgroups could be discriminated based on additional clinical features, distinct quantitative sensory testing profiles, or the interaction of pain severity with the level of post-traumatic stress disorder. Results Persistent post-traumatic headache subjects with migraine-like symptoms reported that bright light and focused attention aggravated their pain, while stress and nervousness were reported to aggravate the headache in subjects with tension-type headache-like symptoms. Quietness was better in alleviating migraine-like persistent post-traumatic headache, while anti-inflammatory medications provided better relief in tension-type headache-like persistent post-traumatic headache. The two persistent post-traumatic headache subgroups exhibited distinct quantitative sensory testing profiles with subjects exhibiting tension-type headache-like persistent post-traumatic headache displaying a more pronounced cephalic and extracephalic thermal hypoalgesia that was accompanied by cephalic mechanical hyperalgesia. While both persistent post-traumatic headache subgroups had high levels of post-traumatic stress disorder, there was a positive correlation with pain severity in subjects with tension-type headache-like symptoms, but a negative correlation in subjects with migraine-like symptoms. Conclusions Distinct persistent post-traumatic headache symptoms and quantitative sensory testing profiles may be linked to different etiologies, potentially involving various levels of neuropathic and inflammatory pain, and if confirmed in a larger cohort, could be used to further characterize and differentiate between persistent post-traumatic headache subgroups in studies aimed to improve treatment.
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Nathu, Ghazala, and Adila Nathu. "189 Comparison of Traditional Therapy Versus Biofeedback for Tension Type and Migraine Headaches." CNS Spectrums 25, no. 2 (April 2020): 319. http://dx.doi.org/10.1017/s1092852920001042.

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Abstract:The effectiveness of biofeedback therapy in treating headache has been explored in various clinical settings. However, few studies in the literature focused on well- diagnosed patients who failed properly applied analgesic treatment. The aim of the study is to explore whether the combination of biofeedback and analgesics is more effective than analgesics alone in treating patients with pharmacologically uncontrolled tension type headache and migraine. The hypothesis is that the combination of biofeedback and analgesics is more effective than analgesics alone in treating patients with uncontrolled tension type headache and migraine.Electromyographic and thermal biofeedback was utilized as an add-on treatment for 25 patients whose tension type headache and migraine was pharmacologically uncontrolled. The effect of the combination therapy was compared with the treatment effect of 25 similar patients, who continued receiving pharmacological treatment alone. All the subjects from the two groups were randomly selected from the pool of patients with uncontrolled tension type headache and migraine. The progress of two groups was closely monitored and data was collected for statistical analysis, which consists of Chi Square, non-parametric ANOVA, and Mann- Whitney U test.Some positive results were observed from the group of patients receiving combination therapy of biofeedback and analgesics, including: reduced use of analgesics, reduced muscle tension, reduced pain score, decrease in intensity, frequency, and duration of headache. These positive outcomes were rarely observed from the comparison group, in which pharmacological treatment was continued alone.The results indicate that the addition of biofeedback to standard analgesic therapy may be more effective than analgesics alone in treating patients with uncontrolled tension type headache and migraine. Further research is suggested to validate these findings and improve treatment effectiveness.
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Covelli, Vito, Giuseppe Polimeno, Maria A. Savarese, Fabio Antonaci, Franco M. Puca, and Anna Tannoia. "Erythrocyte Deformability Changes in Headache Patients Under Flunarizine Treatment." Cephalalgia 5, no. 2_suppl (May 1985): 159–61. http://dx.doi.org/10.1177/03331024850050s230.

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Changes in erythrocyte deformability (ED) parameters have been investigated in 36 patients suffering from different forms of headache (classic and common migraine; migraine with interval headache; chronic tension headache) and treated with flunarizine (10 mg/day at bedtime). Patients were carefully selected in order to avoid any possible interference with the parameters under study, and smoke and drug use in particular (symptomatics included) were considered as criteria for exclusion from the trial. Controls of ED parameters were planned before treatment and after 20 and 35 days. Baseline ED alterations were present only among patients with chronic tension headache, but flunarizine treatment was able to positively modify ED parameters in these patients, as well as in migraine cases that showed normal baseline ED values. No correlation was found between patients' characteristics and baseline ED values, nor between ED changes under treatment and therapeutic effects of flunarizine.
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Hansen, Per Evald, and John Hersted Hansen. "Acupuncture Treatment of Chronic Tension Headache – A Controlled Cross-Over Trial." Cephalalgia 5, no. 3 (September 1985): 137–42. http://dx.doi.org/10.1046/j.1468-2982.1985.0503137.x.

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In a controlled trial the effect of traditional Chinese acupuncture v. placebo acupuncture was evaluated in 18 patients with chronic tension headache (mean disease duration 15 years). All patients suffered from daily or frequently recurring headache, the intensity of which was recorded by the patient over a period of 15 weeks. Each patient was treated by traditional Chinese acupuncture as well as by placebo acupuncture in a cross-over design following randomization. Each period of treatment comprised six treatments. Traditional Chinese acupuncture was found to be significantly more pain-relieving than placebo acupuncture, according to the pain registration of the patients themselves. The pain reduction was 31%. Acupuncture is therefore found to be a reasonable treatment for chronic tension headache.
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Anderson, Rosemary E. "Response to “Osteopathic Treatment Versus Relaxation for Tension-Type Headache”." Headache: The Journal of Head and Face Pain 47, no. 3 (March 19, 2007): 451–52. http://dx.doi.org/10.1111/j.1526-4610.2007.00740.x.

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47

Diamond, S. "Ibuprofen plus caffeine in the treatment of tension-type headache." Clinical Pharmacology & Therapeutics 68, no. 3 (September 2000): 312–19. http://dx.doi.org/10.1067/mcp.2000.109353.

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48

Bove, Geoffrey, and Niels Nilsson. "Spinal Manipulation in the Treatment of Episodic Tension-Type Headache." JAMA 280, no. 18 (November 11, 1998): 1576. http://dx.doi.org/10.1001/jama.280.18.1576.

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Weinman, Danielle, Olivia Nicastro, Olabiyi Akala, and Benjamin W. Friedman. "Parenteral Treatment of Episodic Tension-Type Headache: A Systematic Review." Headache: The Journal of Head and Face Pain 54, no. 2 (January 16, 2014): 260–68. http://dx.doi.org/10.1111/head.12287.

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Kokoska, Mimi S., Dee A. Glaser, Christine M. Burch, and Christopher S. Hollenbeak. "Botulinum toxin injections for the treatment of frontal tension headache." Journal of Headache and Pain 5, no. 2 (August 2004): 103–9. http://dx.doi.org/10.1007/s10194-004-0077-6.

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