Academic literature on the topic 'Terminal care'

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Journal articles on the topic "Terminal care"

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YAMANE, KIYOMI. "Terminal care. Home terminal care." Nihon Naika Gakkai Zasshi 85, no. 12 (1996): 1994–99. http://dx.doi.org/10.2169/naika.85.1994.

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&NA;, &NA;. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 12, no. 2 (March 1985): 70. http://dx.doi.org/10.1097/00152192-198503000-00044.

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&NA;. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 12, no. 4 (July 1985): 150. http://dx.doi.org/10.1097/00152192-198507000-00046.

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&NA;, &NA;. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 12, no. 5 (September 1985): 188. http://dx.doi.org/10.1097/00152192-198509000-00047.

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&NA;, &NA;. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 12, no. 6 (November 1985): 221. http://dx.doi.org/10.1097/00152192-198511000-00058.

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NM, &NA;. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 13, no. 2 (March 1986): 71. http://dx.doi.org/10.1097/00152192-198603000-00048.

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&NA;. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 13, no. 4 (July 1986): 168. http://dx.doi.org/10.1097/00152192-198607000-00057.

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Boarini, Joy. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 13, no. 6 (November 1986): 252. http://dx.doi.org/10.1097/00152192-198611000-00043.

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&NA;. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 14, no. 1 (January 1987): 41. http://dx.doi.org/10.1097/00152192-198701000-00039.

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Boarini, Joy. "Terminal care." Journal of Wound, Ostomy and Continence Nursing 14, no. 3 (May 1987): 131. http://dx.doi.org/10.1097/00152192-198705000-00052.

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Dissertations / Theses on the topic "Terminal care"

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Parker-Oliver, Debra. "The diffusion of hospice care in Missouri /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9988689.

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Damm, Kathryn. "Social support and mental health for terminally ill patients and their caregivers." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3307164.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed July 9, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 86-103).
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Dunbar, Pervell Velethia. "Nursing Care of Terminal patients in Intensive Care Units." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/1379.

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Nursing Care for Terminal Patients in Intensive Care Units by Pervell Dunbar Project Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University August 2015 Although the goal of the ICU has always been to save lives, ICU now additionally provides end-of life (EOL) care. The objective of this project was to provide ICU nurses with a comprehensive awareness of physical, emotional, and spiritual EOL care issues of patients and their families in order to be better equipped to handle EOL care. The framework used was Jean Watson's Caring model (10 Caritas). A literature review revealed a poster previously used by a major health organization as a conversation starter to facilitate decision-making among ICU nurses, EOL patients, and their families related to EOL issues. The purpose of this quality improvement initiative was to introduce and implement an educational EOL tool that would engage patients and family members in meaningful and useful conversations with ICU nurses. Twenty seven ICU nurses were selected by the unit's director to attend a PowerPoint presentation on the use of the EOL educational poster. Four ICU nurses were chosen by the director to be champions for this project. After the presentation, there was a period for questions and answers, and the ICU nurses were requested to give feedback on the presentation. The result from the feedback revealed that EOL care is outside previous practice and may require extra education and support. These comments substantiated similar conclusions from other researchers as described in this paper. With an increase in EOL training for ICU nurses and the implementation of EOL teaching tools like the poster used in this study, ICU nurses may be better able to have conversations with EOL patients and families, thus improving patient care.
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Webb, Nicole Marie. "Factors affecting young adults' opinions about hospice and home death." Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2009p/webb.pdf.

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Thesis (Ph. D.)--University of Alabama at Birmingham, 2009.<br>Title from PDF title page (viewed Sept. 2, 2009). Additional advisors: Virginia G. (Wadley) Bradley, Elizabeth A. Kvale, Kathryn L. Burgio, Edwin W. Cook III. Includes bibliographical references.
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Li, Sarah. "Symbiotic niceness : a study of psychosocial care in palliative care settings." Thesis, Goldsmiths College (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275638.

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Chemane, Bonginkosi Reginald. "Integrating spirituality and psychotherapy : experiences of a sample of terminally ill patients." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1008217.

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The general aim of this study was to determine the experiences of a sample of terminally ill patients in using spiritually focused psychotherapy. This was a qualitative study conducted to a sample of 2 terminally ill patients from hospice in Grahamstown, South Africa. The research was conducted in 3 phases: an initial in-depth interview conducted to determine the participants' level of spirituality as well as the extent to which their terminal illnesses had affected their functioning. This was followed by a minimum of 6 spiritually focused therapy (SFT) sessions as a second phase of the research. To determine the participants' experiences of SFT, 2-3 in-depth interviews were conducted during the 3m phase of the research study. The research revealed that a belief in a higher power helps terminally ill patients cope better with their illness and that social disconnectedness is related to HIV / AIDS stigma. It also revealed that terminal illness is co-morbid with other psychiatric symptoms such as depression, evokes existential concerns, results in a change in the level of spirituality and affects the whole family. Participants blamed themselves for their illness, but found that engaging in the process of forgiveness of self and others brought about psychological healing for them. They experienced SFT as a coping resource that assisted them to deal with the fear of death as well as increased insight into the development of psychopathology and spiritual blockages. It is recommended that a comprehensive and holistic assessment during intake be undertaken so that where spiritual needs are available, therapy can be spiritually augmented to ensure that such needs/ struggles are addressed.<br>KMBT_363<br>Adobe Acrobat 9.54 Paper Capture Plug-in
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Cho, Yuen-yee Christine. "Hospice." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2595099x.

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Chapman, Ysanne B. "The lived experience of nursing dying or dead people /." View thesis, 1994. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030617.120150/index.html.

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Walker, Helen M. "The experience of care assistants who care for residents in the final stage of life in residential aged care facilities." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2007. https://ro.ecu.edu.au/theses/278.

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This thesis presents the results of a study that explores the experience of care assistants who care for residents in the final stages of life in residential aged care facilities in metropolitan Perth. Care assistants, with little formal training and no regulation, play a pivotal role in the direct care of dying residents in these facilities. Yet little was known about the palliative care role and the impact that caring for residents in the final stage of life has on this health care group. The literature relating to end of life care in residential aged care facilities revealed limited research in this area. In particular, there is a lack of studies that relate specifically to the care assistants' role and their experiences of end of life care. Research to date has focused on the context of palliative care in residential aged care facilities, the workplace environment, how to provide a dignified death, relationships and the central role of the care assistant. This study used a qualitative narrative inquiry research design.
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Ho, Man-chuen Anthony. "A hospice in Sandy Bay." Hong Kong : University of Hong Kong, 1995. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25946043.

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Books on the topic "Terminal care"

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Stookey, Christopher. Terminal care. Holliston, Mass: Silver Leaf Books, 2010.

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Practitioners, Royal College of General. Terminal care. London: Royal College ofGeneral Practitioners, 1989.

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Stookey, Christopher. Terminal care. Holliston, Mass: Silver Leaf Books, 2010.

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Eric, Wilkes, Knight Margaret 1956-, and Fitzpatrick Trevor, eds. Terminal care. Guildford: Update-Siebert Publications, 1986.

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Richard, Turnbull, ed. Terminal care. Washington: Hemisphere Pub. Corp., 1986.

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Hanratty, J. F. Palliative care in terminal illness. 2nd ed. Oxford: Radcliffe Medical, 1994.

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Rumbold, Bruce D. Helplessness and hope: Pastoral care in terminal illness. London: SCM Press, 1986.

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Roy, Spilling, ed. Terminal care at home. Oxford: Oxford University Press, 1986.

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Roy, Spilling, ed. Terminal care at home. Oxford: Oxford University Press, 1986.

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B, Seeland Irene, ed. The Final 48 hours: Observations on the last days of life. Philadelphia: Charles Press, 1991.

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Book chapters on the topic "Terminal care"

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Wilson, Christine. "Terminal care." In Health Psychology, 405–18. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3226-6_23.

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Twycross, R. "Terminal Care." In Surgical Oncology, 296–305. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-72646-0_27.

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Heller, Lois Jane, Celette Sugg Skinner, A. Janet Tomiyama, Elissa S. Epel, Peter A. Hall, Julia Allan, Lara LaCaille, et al. "Terminal Care." In Encyclopedia of Behavioral Medicine, 1963. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101769.

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Fry, John, John Trounce, and Martin Godfrey. "Terminal Care." In Commonsense use of Medicines, 183–92. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1295-3_15.

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Owen, Rhian E. "Terminal Care." In Geriatric Medicine, 321–31. London: Springer London, 1989. http://dx.doi.org/10.1007/978-1-4471-1646-2_26.

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Fry, John. "Terminal Care." In The Beecham Manual for Family Practice, 87–91. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-011-6361-3_7.

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Maxwell, Terri L. "Terminal Secretions." In Case Studies in Palliative and End-of-Life Care, 213–19. West Sussex, UK: John Wiley & Sons, Inc.,, 2013. http://dx.doi.org/10.1002/9781118704707.ch27.

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Faull, Christina, and Alex Nicholson. "Terminal Care and Dying." In Handbook of Palliative Care, 295–322. Hoboken, New Jersey: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118426869.ch21.

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Sloan, John P. "Terminal or Palliative Care." In Protocols in Primary Care Geriatrics, 105–9. New York, NY: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-0388-6_17.

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Szawarski, Zbigniew. "Terminal Care and Ethics." In Bioethics in a European Perspective, 433–51. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-015-9706-7_14.

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Conference papers on the topic "Terminal care"

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Bayer, George T., Mehrooz Zamanzadeh, Anil Kumar Chikkam, and Aaron Ulmer. "Investigation of Painted Steel Piles at a Marine Commerce Terminal in Coastal New England." In CONFERENCE 2023, 1–15. AMPP, 2023. https://doi.org/10.5006/c2023-18780.

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Abstract This case study presents the results and conclusions of an investigation of painted steel piles at a marine commerce terminal in coastal New England, including a review of relevant engineering specifications and other documents, an on-site field investigation, and laboratory analysis of samples collected. A review of specifications showed that the specifications approved for the paint system were inadequate for long term service without using cathodic protection. No cathodic protection was placed on the back side of piles and should be extended to back side for corrosive soil exposure. After five years, the paint coating looks good in non-repaired areas. No corrosion or blisters were observed in non-repaired areas in the atmospheric zone or in areas where there is no mechanical damage or barnacles. Maintenance/repair coating of the previously repaired and mechanically damaged areas and cathodic protection monitoring can take care of problems. No corrosion or accelerated corrosion in blisters was observed due to cathodic protection and high pH. Indications are that barnacles contributed and may have caused the blisters.
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Bao, Xiangyu, Funing Jia, Jingshu Zhong, Lei Zhang, Changhui Liu, Liang Chen, and Yu Zheng. "Digital twin system for automated container terminal and a case study*." In 2024 IEEE 20th International Conference on Automation Science and Engineering (CASE), 142–47. IEEE, 2024. http://dx.doi.org/10.1109/case59546.2024.10711351.

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Wang, Jingyao, Jialu Du, and Frank L. Lewis. "Distributed Fixed-Time Nonsingular Terminal Sliding Mode 3-D Formation Control of Underactuated AUVs." In 2024 9th International Conference on Automation, Control and Robotics Engineering (CACRE), 329–33. IEEE, 2024. http://dx.doi.org/10.1109/cacre62362.2024.10635094.

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Cavalcante, Hiago L., Derek N. A. Alves, Lucas Amaral, and Tiago F. Vieira. "Screen Scratch Detection on Credit Card Payment Terminals for Logistics Optimization." In 2024 XIV Brazilian Symposium on Computing Systems Engineering (SBESC), 1–6. IEEE, 2024. https://doi.org/10.1109/sbesc65055.2024.10771821.

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Janssen, Daisy, Martijn A. Spruit, Jos M. G. A. Schols, and Emiel F. M. Wouters. "Poor Agreement Between Preferred Site Of Terminal Care And Actual Site Of Terminal Care Among Patients With Advanced Chronic Organ Failure." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5216.

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Hua, M., X. Ma, R. S. Morrison, G. Li, and H. Wunsch. "Implementation of Hospital-Based Palliative Care Services and Use of Intensive Care During Terminal Hospitalizations." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7047.

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Zhang, Ruihan, Zhan Zhao, Zhen Fang, and Shulei Chu. "A Health Care Monitoring Terminal Based on Android Smart Phone." In First International Conference on Information Science and Electronic Technology (ISET 2015). Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/iset-15.2015.23.

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Naito, Yumi, Yoko Tomita, Katrina Breaden, and Yvonne Parry. "PP11.001 Community nurses’ perspectives on barriers to effective utilisation of advance care planning for terminal care in Japan." In ACP international Conference 2023 Abstracts. British Medical Journal Publishing Group, 2023. http://dx.doi.org/10.1136/spcare-2023-acp.78.

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Iwaniszak, Claire, Elizabeth Rees, Rachael Meal, Anna Winfield, Craig Pattison, Katie Hodge, and Suzanne Kite. "165 Improving care of patients with terminal agitation (ta) at end of life at leeds teaching hospitals nhs trust." In The APM’s Annual Supportive and Palliative Care Conference, In association with the Palliative Care Congress, “Towards evidence based compassionate care”, Bournemouth International Centre, 15–16 March 2018. British Medical Journal Publishing Group, 2018. http://dx.doi.org/10.1136/bmjspcare-2018-aspabstracts.192.

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Alencar, Rafisah Sekeff Simão, Larissa Bispo Alves Roncen, Maria Eduarda de Oliveira Rodrigues, and Marcos Curcio Angelini. "Glioblastoma and Palliative Care." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.090.

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Background: Glioblastoma is a primary malignant tumor of the central nervous system with 12 to 15 month survival. Its prognosis, considering the initial diagnosis, equals to stage 4 of other types of cancer, being recommended to consider palliative care, with advanced care planning, at an early stage of the disease. Such care is complex due to the significant symptoms, being necessary to reduce the symptomatic charge to maintain the patient’s quality of life. Objective: Analyze the early practice of palliation in patients with glioblastoma. Methods: A literature review was carried out on the PubMed, BVS and Scielo platforms using the descriptors: “Glioblastoma” AND “Palliative Care.” 7 articles were selected in the english language, published in the last 5 years. Results: The quality of life of patients with glioblastoma gradually reduces. In that sense, cognitive decline compromises end-of-life care with relation to patient autonomy. However, antecipate guidelines were found completed late to the course of the disease, possibly after loss of decisionmaking capacity. Moreover, despite the proven benefits of palliation, early involvement of palliative care is rare in neuro- oncology, with the excessive use of chemotherapy among terminal patients. Conclusions: The late practice of palliation and of early guidelines in patients with glioblastoma affect the management of symptoms and quality of life of those patients.
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Reports on the topic "Terminal care"

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Philipson, Tomas, Gary Becker, Dana Goldman, and Kevin Murphy. Terminal Care and The Value of Life Near Its End. Cambridge, MA: National Bureau of Economic Research, January 2010. http://dx.doi.org/10.3386/w15649.

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Becker, Gary, Kevin Murphy, and Tomas Philipson. The Value of Life Near its End and Terminal Care. Cambridge, MA: National Bureau of Economic Research, August 2007. http://dx.doi.org/10.3386/w13333.

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Svynarenko, Radion, Guoping Huang, Theresa L. Profant, and Lisa C. Lindley. Effectiveness of End-of-Life Strategies to Improve Health Outcomes and Reduce Disparities in Rural Appalachia: An Analytic Codebook. Pediatric End-of-Life (PedEOL) Care Research Group, College of Nursing, University of Tennessee, Knoxville, 2023. http://dx.doi.org/10.7290/n89xhm.

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Appalachia is one of the most medically underserved areas in the nation. The region has provider shortages and limited healthcare infrastructure. Children and adolescents in this area are in poor health and do not receive the needed quality care. Implementation of section 2302 of the 2010 Patient Protection and Affordable Care Act (ACA) enabled children enrolled in Medicaid/Children's Health Insurance Program with a terminal illness to use hospice care while continuing treatment for their terminal illness. In addition to being more comprehensive than standard hospice care, this relatively new type of care is more culturally congruent with the end-of-life values of rural Appalachian families, who often view standard hospice as hastening death. The overall goal of this project was to investigate access to pediatric concurrent hospice care in Appalachia. Our central hypothesis was that concurrent care reduces rural/urban disparities in access to hospice care. Data from the Centers for Medicare and Medicaid Services (CMS) used in this project was used and included 1,788 children who resided in the Appalachian region– from January 1, 2011, to December 31, 2013. Observations with missing birth dates, death dates, and participants older than 21 years were removed from the final sample. Geographic Information Systems (GIS) databases were created to map the boundaries of the Appalachian region, hospice locations, and driving times to them.
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Neal, Margaret. Socialization and ideal expectations for the health professional role in the provision of quality terminal care for the urban elderly. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.332.

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Svynarenko, Radion, Theresa L. Profant, and Lisa C. Lindley. Effectiveness of concurrent care to improve pediatric and family outcomes at the end of life: An analytic codebook. Pediatric End-of-Life (PedEOL) Care Research Group, College of Nursing, University of Tennessee, Knoxville, 2022. http://dx.doi.org/10.7290/m5fbbq.

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Implementation of the section 2302 of the 2010 Patient Protection and Affordable Care Act (ACA) enabled children enrolled in Medicaid/Children's Health Insurance Program with a prognosis of 6 months to live to use hospice care while continuing treatment for their terminal illness. Although concurrent hospice care became available more than a decade ago, little is known about the socio-demographic and health characteristics of children who received concurrent care; health care services they received while enrolled in concurrent care, their continuity, management, intensity, fragmentation; and the costs of care. The purpose of this study was to answer these questions using national data from the Centers of Medicare and Medicaid Services (CMS), which covered the first three years of ACA – from January 1, 2011, to December 31, 2013.The database included records of 18,152 children younger than the age of 20, who were enrolled in Medicaid hospice care in the sampling time frame. Children in the database also had a total number of 42,764 hospice episodes. Observations were excluded if the date of birth or death was missing or participants were older than 21 years. To create this database CMS data were merged with three other complementary databases: the National Death Index (NDI) that provided information on death certificates of children; the U.S. Census Bureau American Community Survey that provided information on characteristics of communities where children resided; CMS Hospice Provider of Services files and CMS Hospice Utilization and Payment files were used for data on hospice providers, and with a database of rural areas created by the Health Resources and Services Administration (HRSA). In total, 130 variables were created, measuring demographics and health characteristics of children, characteristics of health providers, community characteristics, clinical characteristics, costs of care, and other variables.
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Fang, Mei Lan, Marianne Cranwell, Becky White, Gavin Wylie, Karen Lok Yi Wong, Kevin Harter, Lois Cosgrave, et al. Aging-in-Place at the End-of-Life in Community and Residential Care Contexts. University of Dundee, January 2023. http://dx.doi.org/10.20933/100001274.

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Population aging is a global phenomenon that has presented capacity and resource challenges for providing supportive care environments for older people in later life (Bone et al., 2018, Finucane et al., 2019). Aging-in-place was introduced as a policy driver for creating supportive environmental and social care to enable individuals to live independently at home and in the community for as long as possible. Recently, there has been a move towards offering care for people with a terminal illness at home and in the community (Shepperd et al., 2016); and when appropriate, to die in supportive, home-like environments such as care homes (Wada et al., 2020). Aging-in-place principles can, thus and, should be extended to enabling supportive, home-like environments at the end-of-life. Yet, first, we must consider the appropriateness, availability and diversity of options for community-based palliative and end-of-life care (PEoLC), in order to optimise supports for older people who are dying at home or within long-term/residential care environments. Globally, across places with similar health and social care systems and service models such as in Scotland and in Canada, community-based PEoLC options are currently not uniformly available. Given that people entering into long-term/residential care homes are increasingly closer to the end of life, there is now an even greater demand for PEoLC provision in residential facilities (Kinley et al., 2017). Although most reported deaths occur within an inpatient hospital setting (50%), the proportion of overall deaths in a care home setting is projected to increase from 18% to 22.5% (Finucane et al, 2019). This suggests that long-term/residential care homes are to become the most common place of death by 2040, evidencing the need to develop and sustain appropriate and compassionate PEoLC to support those who are able to die at home and those living in residential care facilities (Bone et al., 2018; Finucane et al., 2019). This research initiative is premised on the notion that aging in place matters throughout the life-course, including at the end-of-life and that the socio-environmental aspects of care homes need to enable this.
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Go, Eugenia, Kentaro Nakajima, Yasuyuki Sawada, and Kiyoshi Taniguchi. On the Use of Satellite-Based Vehicle Flows Data to Assess Local Economic Activity: The Case of Philippine Cities. Asian Development Bank, March 2022. http://dx.doi.org/10.22617/wps220079-2.

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Satellite image-derived vehicle counts were used to measure local economic activity following the opening of the new terminal at the Mactan-Cebu International Airport in the Philippines. Results reveal that the terminal’s opening has had positive impacts on Cebu’s local economy. A comparison of the vehicle count measure with luminosity-derived metrics suggests that the former is better at capturing seasonal and spatial variations in treatment effects, especially for beach tourism activities in Cebu.
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Avihingsanon, Yingyos, Jongkonnee Wongpiyabovorn, and Nattiya Hirankarn. Biomarker discovery in systemic lupus erythematosus: genome-methylation approaches : Research report. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.15.

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Discovery of novel biomarkers in lupus nephritis Biomarkers are needed for making diagnosis and prognosis. In lupus nephritis, conventional tests like urinalysis or serum creatinine remain inadequate for patient care. In this proposal, we focused on non-invasive tools like blood and urine mRNAs or proteins. We chose candidate genes involving regulatory T-cell, B-lymphocyte signatures or vascular protective factors. Expression of regulatory cell signature (FOXP3) in peripheral blood mononuclear cells is associated with activity of lupus nephritis. We found FOXP3 mRNA levels in PBMCs from patients with active lupus nephritis were significantly lower than inactive lupus nephritis. Expression levels of FOXP3 mRNA were associated with pathological activity index, cellular crescent and fibrinoid necrosis. BLyS and APRIL are B-lymphocyte related cytokines that play an important role in generating and maintaining the mature B-cell pool. In this study, we found blood APRIL correlated with activity of lupus nephritis. Blood APRIL levels could precisely predict failure of standard treatment treatment. APRIL is a potential biomarker for predicting treatment failure. Lastly, we found an expression of VEGF in renal tissue may serve as a molecular marker of renal damage from LN and may be a predictive factor for short-term loss of kidney function in lupus nephritis patients. We proposed that reduction of intra-renal VEGF level caused by losses of podocyte cells. Genetic polymorphism of drug toxicity or pharmacokinetics in SLE patients We began to explore the pharmacokinetics and pharmacogenomics of two important immunosuppressants, azathioprine and mycophenolate. In this study, we report TPMT polymorphisms and TPMT enzyme activity were important predictors of AZA-induced myelosuppression. The tests are available for routine care. Mycophenolic acid (MPA) is active metabolite of mycophenalate. We found MPA levels is important predictor of therapeutic response. The therapeutic drug monitoring is now an important issue of patient care. We found UGT1A9 polymorphism may play a pivotal role in drug metabolisms. Methylation study We examined and compared the methylation levels of long terminal repeats (LTRs) and non-LTR retroelements in normal and SLE CD4+ T lymphocytes, CD8+ T lymphocytes and B lymphocytes. Hypomethylation of LINE-1 but not Alu was found in CD4+ T lymphocytes, CD8+ T lymphocytes, and B lymphocytes of SLE patient. Moreover, when the SLE patients were divided into active and inactive groups, LINE-1 hypomethylation was more significantly distinguished in both CD4+ and CD8+ T lymphocytes of patients from the active SLE group when compared to the controls. Genome-wide scanning using SNP microarrays In this study, we applied case-control association study including pooling genome wide association (GWA) and candidate gene association studies to search for SNPs associated with SLE susceptibility and/or severity. We could not identify any SNPs with distinct p-value or odds ratio from our pooling GWA result due to limited power. We selected IFIX for further study in candidate gene’s part. Besides IFIX, we also focus on MNDA, IFI16 and AIM2 genes which located in the same region and are all IFN-inducible genes. They are important SLE susceptibility genes due to several reasons including 1) genetic mapping from lupus murine model and 2) an upregulated IFN-inducible genes in patients with SLE from microarray studies and 3) IFI16 was identified as new autoantigen for patients with SLE. We genotyped 10 SNPs from these 4 genes and found that SNP within IFIX and IFI16 are independently important.
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Beavers, John. PR-186-073503-R02 Requirements for Existing Pipeline Tank and Terminal Systems to Transport Ethanol. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), June 2010. http://dx.doi.org/10.55274/r0010439.

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The potential exists for stress corrosion cracking (SCC) of carbon steel pipelines transporting fuel grade ethanol (FGE) and FGE- gasoline blends. The objectives of SCC 4-4 were to: 1. Develop data necessary to make engineering assessments of the feasibility of transporting FGE and FGE blends in existing pipelines, 2. Identify ethanol blends that can be transported in existing pipelines without significant modification of the system and operations (Case 1); blends that require significant modifications (Case 2) and blends that cannot be transported in existing pipelines, but could be moved in specially designed systems (Case 3), and 3. Characterize the time to initiation of SCC in a range of potent ethanol environments and identify safe operating and or batching practices that prevent the initiation and growth of SCC. The results of the research (Phase 1 and Phase 2) demonstrated that: 1. Pipelines made of common line pipe steels (e.g., Grade B and X-42 to X-60) are likely to be susceptible to ethanol SCC and any differences in susceptibility are probably not relevant from an integrity perspective. 2. While differences in susceptibility were noted for some weld types, in general, the base metal, heat affected zone, and weld metal were all susceptible to SCC in SFGE. 3. For sharp cracks, SCC initiation times are short once the line pipe steel is exposed to FGE or FGE blends capable of promoting SCC. 4. Once cracks initiate, crack growth rates are high in comparison with other forms of pipeline SCC. 5. Batching does not appear to be a viable method for SCC mitigation. 6. The only blends that can be safely transported in existing pipelines without significant modification of the system or operations (Case 1) are those containing less than 15% ethanol. 7. All other blends require significant modifications of the system or operations (Case 2), or specially designed systems (Case 3). 8. Case 2 could include deaeration of the SFGE, or the addition of inhibitors. 9. Case 3 is the subject of ongoing research (SCC 4-5).
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Suárez Alemán, Ancor, José Yitani Ríos, Paula Castillo Martínez, Gastón Astesiano, and Julio Franco Corzo. Case Studies in Public-Private Partnerships in Latin America and the Caribbean: Kingston Container Terminal (Jamaica). Inter-American Development Bank, July 2020. http://dx.doi.org/10.18235/0002485.

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