Relevant bibliographies by topics / Terpene biosynthesis

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Terpene biosynthesis'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Terpene biosynthesis.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Terpene biosynthesis"

1

Sayari, Mohammad, Magrieta A. van der Nest, Emma T. Steenkamp, Saleh Rahimlou, Almuth Hammerbacher, and Brenda D. Wingfield. "Characterization of the Ergosterol Biosynthesis Pathway in Ceratocystidaceae." Journal of Fungi 7, no. 3 (March 22, 2021): 237. http://dx.doi.org/10.3390/jof7030237.

Full text
Abstract:
Terpenes represent the biggest group of natural compounds on earth. This large class of organic hydrocarbons is distributed among all cellular organisms, including fungi. The different classes of terpenes produced by fungi are mono, sesqui, di- and triterpenes, although triterpene ergosterol is the main sterol identified in cell membranes of these organisms. The availability of genomic data from members in the Ceratocystidaceae enabled the detection and characterization of the genes encoding the enzymes in the mevalonate and ergosterol biosynthetic pathways. Using a bioinformatics approach, fungal orthologs of sterol biosynthesis genes in nine different species of the Ceratocystidaceae were identified. Ergosterol and some of the intermediates in the pathway were also detected in seven species (Ceratocystis manginecans, C. adiposa, Huntiella moniliformis, Thielaviopsis punctulata, Bretziella fagacearum, Endoconidiophora polonica and Davidsoniella virescens), using gas chromatography-mass spectrometry analysis. The average ergosterol content differed among different genera of Ceratocystidaceae. We also identified all possible terpene related genes and possible biosynthetic clusters in the genomes used in this study. We found a highly conserved terpene biosynthesis gene cluster containing some genes encoding ergosterol biosynthesis enzymes in the analysed genomes. An additional possible terpene gene cluster was also identified in all of the Ceratocystidaceae. We also evaluated the sensitivity of the Ceratocystidaceae to a triazole fungicide that inhibits ergosterol synthesis. The results showed that different members of this family behave differently when exposed to different concentrations of triazole tebuconazole.
APA, Harvard, Vancouver, ISO, and other styles
2

Chekan, Jonathan R., Shaun M. K. McKinnie, Joseph P. Noel, and Bradley S. Moore. "Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into anN-prenyltransferase." Proceedings of the National Academy of Sciences 117, no. 23 (May 26, 2020): 12799–805. http://dx.doi.org/10.1073/pnas.2001325117.

Full text
Abstract:
Prenylation is a common biological reaction in all domains of life wherein prenyl diphosphate donors transfer prenyl groups onto small molecules as well as large proteins. The enzymes that catalyze these reactions are structurally distinct from ubiquitous terpene cyclases that, instead, assemble terpenes via intramolecular rearrangements of a single substrate. Herein, we report the structure and molecular details of a new family of prenyltransferases from marine algae that repurposes the terpene cyclase structural fold for theN-prenylation of glutamic acid during the biosynthesis of the potent neurochemicals domoic acid and kainic acid. We solved the X-ray crystal structure of the prenyltransferase found in domoic acid biosynthesis, DabA, and show distinct active site binding modifications that remodel the canonical magnesium (Mg2+)-binding motif found in terpene cyclases. We then applied our structural knowledge of DabA and a homologous enzyme from the kainic acid biosynthetic pathway, KabA, to reengineer their isoprene donor specificities (geranyl diphosphate [GPP] versus dimethylallyl diphosphate [DMAPP]) with a single amino acid change. While diatom DabA and seaweed KabA enzymes share a common evolutionary lineage, they are distinct from all other terpene cyclases, suggesting a very distant ancestor to the larger terpene synthase family.
APA, Harvard, Vancouver, ISO, and other styles
3

Helfrich, Eric J. N., Geng-Min Lin, Christopher A. Voigt, and Jon Clardy. "Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering." Beilstein Journal of Organic Chemistry 15 (November 29, 2019): 2889–906. http://dx.doi.org/10.3762/bjoc.15.283.

Full text
Abstract:
Terpenoids are the largest and structurally most diverse class of natural products. They possess potent and specific biological activity in multiple assays and against diseases, including cancer and malaria as notable examples. Although the number of characterized terpenoid molecules is huge, our knowledge of how they are biosynthesized is limited, particularly when compared to the well-studied thiotemplate assembly lines. Bacteria have only recently been recognized as having the genetic potential to biosynthesize a large number of complex terpenoids, but our current ability to associate genetic potential with molecular structure is severely restricted. The canonical terpene biosynthetic pathway uses a single enzyme to form a cyclized hydrocarbon backbone followed by modifications with a suite of tailoring enzymes that can generate dozens of different products from a single backbone. This functional promiscuity of terpene biosynthetic pathways renders terpene biosynthesis susceptible to rational pathway engineering using the latest developments in the field of synthetic biology. These engineered pathways will not only facilitate the rational creation of both known and novel terpenoids, their development will deepen our understanding of a significant branch of biosynthesis. The biosynthetic insights gained will likely empower a greater degree of engineering proficiency for non-natural terpene biosynthetic pathways and pave the way towards the biotechnological production of high value terpenoids.
APA, Harvard, Vancouver, ISO, and other styles
4

Kemper, Katarina, Max Hirte, Markus Reinbold, Monika Fuchs, and Thomas Brück. "Opportunities and challenges for the sustainable production of structurally complex diterpenoids in recombinant microbial systems." Beilstein Journal of Organic Chemistry 13 (May 8, 2017): 845–54. http://dx.doi.org/10.3762/bjoc.13.85.

Full text
Abstract:
With over 50.000 identified compounds terpenes are the largest and most structurally diverse group of natural products. They are ubiquitous in bacteria, plants, animals and fungi, conducting several biological functions such as cell wall components or defense mechanisms. Industrial applications entail among others pharmaceuticals, food additives, vitamins, fragrances, fuels and fuel additives. Central building blocks of all terpenes are the isoprenoid compounds isopentenyl diphosphate and dimethylallyl diphosphate. Bacteria like Escherichia coli harbor a native metabolic pathway for these isoprenoids that is quite amenable for genetic engineering. Together with recombinant terpene biosynthesis modules, they are very suitable hosts for heterologous production of high value terpenes. Yet, in contrast to the number of extracted and characterized terpenes, little is known about the specific biosynthetic enzymes that are involved especially in the formation of highly functionalized compounds. Novel approaches discussed in this review include metabolic engineering as well as site-directed mutagenesis to expand the natural terpene landscape. Focusing mainly on the validation of successful integration of engineered biosynthetic pathways into optimized terpene producing Escherichia coli, this review shall give an insight in recent progresses regarding manipulation of mostly diterpene synthases.
APA, Harvard, Vancouver, ISO, and other styles
5

Wang, Xin, Wei Liu, Changpeng Xin, Yi Zheng, Yanbing Cheng, Su Sun, Runze Li, et al. "Enhanced limonene production in cyanobacteria reveals photosynthesis limitations." Proceedings of the National Academy of Sciences 113, no. 50 (November 23, 2016): 14225–30. http://dx.doi.org/10.1073/pnas.1613340113.

Full text
Abstract:
Terpenes are the major secondary metabolites produced by plants, and have diverse industrial applications as pharmaceuticals, fragrance, solvents, and biofuels. Cyanobacteria are equipped with efficient carbon fixation mechanism, and are ideal cell factories to produce various fuel and chemical products. Past efforts to produce terpenes in photosynthetic organisms have gained only limited success. Here we engineered the cyanobacterium Synechococcus elongatus PCC 7942 to efficiently produce limonene through modeling guided study. Computational modeling of limonene flux in response to photosynthetic output has revealed the downstream terpene synthase as a key metabolic flux-controlling node in the MEP (2-C-methyl-d-erythritol 4-phosphate) pathway-derived terpene biosynthesis. By enhancing the downstream limonene carbon sink, we achieved over 100-fold increase in limonene productivity, in contrast to the marginal increase achieved through stepwise metabolic engineering. The establishment of a strong limonene flux revealed potential synergy between photosynthate output and terpene biosynthesis, leading to enhanced carbon flux into the MEP pathway. Moreover, we show that enhanced limonene flux would lead to NADPH accumulation, and slow down photosynthesis electron flow. Fine-tuning ATP/NADPH toward terpene biosynthesis could be a key parameter to adapt photosynthesis to support biofuel/bioproduct production in cyanobacteria.
APA, Harvard, Vancouver, ISO, and other styles
6

Agliassa, Chiara, and Massimo Maffei. "Origanum vulgare Terpenoids Induce Oxidative Stress and Reduce the Feeding Activity of Spodoptera littoralis." International Journal of Molecular Sciences 19, no. 9 (September 18, 2018): 2805. http://dx.doi.org/10.3390/ijms19092805.

Full text
Abstract:
Terpenoids are toxic compounds produced by plants as a defense strategy against insect herbivores. We tested the effect of Origanum vulgare terpenoids on the generalist herbivore Spodoptera littoralis and the response of the plant to herbivory. Terpenoids were analyzed by GC-FID and GC-MS and quantitative gene expression (qPCR) was evaluated on selected plant genes involved in both terpene biosynthesis. The insect detoxification response to terpenes was evaluated by monitoring antioxidant enzymes activity and expression of insect genes involved in terpene detoxification. O. vulgare terpenoid biosynthesis and gene expression was modulated by S. littoralis feeding. The herbivore-induced increased level of terpenoids (particularly carvacrol and p-cymene) interacted with the herbivore by decreasing larval survival and growth rate. The assimilation by S. littoralis of more than 50% of ingested terpenes correlated with the possible toxic effects of O. vulgare terpenoids. In choice test experiments, carvacrol and γ-terpinene mediated the larval feeding preferences, wherease the prolonged feeding on O. vulgare terpenoids (particularly on γ-terpinene) exerted relevant antinutritional effects on larvae. S. littoralis was found to react to O. vulgare terpenoids by increasing its antioxidant enzymes activities and gene expression, although this was not sufficient to sustain the toxicity of O. vulgare terpenoids.
APA, Harvard, Vancouver, ISO, and other styles
7

He, Xueying, Huan Wang, Jinfen Yang, Ke Deng, and Teng Wang. "RNA sequencing on Amomum villosum Lour. induced by MeJA identifies the genes of WRKY and terpene synthases involved in terpene biosynthesis." Genome 61, no. 2 (February 2018): 91–102. http://dx.doi.org/10.1139/gen-2017-0142.

Full text
Abstract:
Amomum villosum Lour. is an important Chinese medicinal plant that has diverse medicinal functions, and mainly contains volatile terpenes. This study aims to explore the WRKY transcription factors (TFs) and terpene synthase (TPS) unigenes that might be involved in terpene biosynthesis in A. villosum, and thus providing some new information on the regulation of terpenes in plants. RNA sequencing of A. villosum induced by methyl jasmonate (MeJA) revealed that the WRKY family was the second largest TF family in the transcriptome. Thirty-six complete WRKY domain sequences were expressed in response to MeJA. Further, six WRKY unigenes were highly correlated with eight deduced TPS unigenes. Ultimately, we combined the terpene abundance with the expression of candidate WRKY TFs and TPS unigenes to presume a possible model wherein AvWRKY61, AvWRKY28, and AvWRKY40 might coordinately trans-activate the AvNeoD promoter. We propose an approach to further investigate TF unigenes that might be involved in terpenoid biosynthesis, and identified four unigenes for further analyses.
APA, Harvard, Vancouver, ISO, and other styles
8

Oldfield, Eric, and Fu-Yang Lin. "Terpene Biosynthesis: Modularity Rules." Angewandte Chemie International Edition 51, no. 5 (November 21, 2011): 1124–37. http://dx.doi.org/10.1002/anie.201103110.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Lancaster, Jason, Ashot Khrimian, Sharon Young, Bryan Lehner, Katrin Luck, Anna Wallingford, Saikat Kumar B. Ghosh, et al. "De novo formation of an aggregation pheromone precursor by an isoprenyl diphosphate synthase-related terpene synthase in the harlequin bug." Proceedings of the National Academy of Sciences 115, no. 37 (August 23, 2018): E8634—E8641. http://dx.doi.org/10.1073/pnas.1800008115.

Full text
Abstract:
Insects use a diverse array of specialized terpene metabolites as pheromones in intraspecific interactions. In contrast to plants and microbes, which employ enzymes called terpene synthases (TPSs) to synthesize terpene metabolites, limited information from few species is available about the enzymatic mechanisms underlying terpene pheromone biosynthesis in insects. Several stink bugs (Hemiptera: Pentatomidae), among them severe agricultural pests, release 15-carbon sesquiterpenes with a bisabolene skeleton as sex or aggregation pheromones. The harlequin bug, Murgantia histrionica, a specialist pest of crucifers, uses two stereoisomers of 10,11-epoxy-1-bisabolen-3-ol as a male-released aggregation pheromone called murgantiol. We show that MhTPS (MhIDS-1), an enzyme unrelated to plant and microbial TPSs but with similarity to trans-isoprenyl diphosphate synthases (IDS) of the core terpene biosynthetic pathway, catalyzes the formation of (1S,6S,7R)-1,10-bisaboladien-1-ol (sesquipiperitol) as a terpene intermediate in murgantiol biosynthesis. Sesquipiperitol, a so-far-unknown compound in animals, also occurs in plants, indicating convergent evolution in the biosynthesis of this sesquiterpene. RNAi-mediated knockdown of MhTPS mRNA confirmed the role of MhTPS in murgantiol biosynthesis. MhTPS expression is highly specific to tissues lining the cuticle of the abdominal sternites of mature males. Phylogenetic analysis suggests that MhTPS is derived from a trans-IDS progenitor and diverged from bona fide trans-IDS proteins including MhIDS-2, which functions as an (E,E)-farnesyl diphosphate (FPP) synthase. Structure-guided mutagenesis revealed several residues critical to MhTPS and MhFPPS activity. The emergence of an IDS-like protein with TPS activity in M. histrionica demonstrates that de novo terpene biosynthesis evolved in the Hemiptera in an adaptation for intraspecific communication.
APA, Harvard, Vancouver, ISO, and other styles
10

Ichikawa, Yoshiyasu, Toshiki Yamasaki, Keisuke Nakanishi, Yutaro Udagawa, Seijiro Hosokawa, and Toshiya Masuda. "Bioinspired Synthesis of the Central Core of Halichonadin H: The Passerini Reaction in a Hypothetical Biosynthesis of Marine Natural Products." Synthesis 51, no. 11 (March 14, 2019): 2305–10. http://dx.doi.org/10.1055/s-0037-1610867.

Full text
Abstract:
A pathway is proposed for the biosynthesis of the unique homodimeric terpene, halichonadin H. The proposed biosynthetic pathway involves two key Passerini reactions of eudesmane-type terpene isocyanides. The Passerini reaction of a model terpene isocyanide and formaldehyde afforded an α-hydroxy acetamide, which was further subjected to oxidation and a second Passerini reaction. This reaction sequence furnished an α-hydroxy malonamide connected with two identical terpene units which is the identical structural motif found in halichonadin H.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Terpene biosynthesis"

1

Greenhagen, Bryan T. "ORIGINS OF ISOPRENOID DIVERSITY: A STUDY OF STRUCTURE-FUNCTION RELATIONSHIPS IN SESQUITERPENE SYNTHASES." UKnowledge, 2003. http://uknowledge.uky.edu/gradschool_diss/440.

Full text
Abstract:
Plant sesquiterpene synthases catalyze the conversion of the linear substrate farnesyl diphosphate, FPP, into a remarkable array of secondary metabolites. These secondary metabolites in turn mediate a number of important interactions between plants and their environment, such as plant-plant, plant-insect and plant-pathogen interactions. Given the relative biological importance of sesquiterpenes and their use in numerous practical applications, the current thesis was directed towards developing a better understanding of the mechanisms employed by sesquiterpene synthases in the biosynthesis of such a diverse class of compounds. Substrate preference for sesquiterpene synthases initially isolated from Nicotiana tabacum (TEAS), Hyoscyamus muticus (HPS) and Artemisia annuna (ADS) were optimized with regards to a divalent metal ion requirement. Surprisingly, careful titration with manganese stimulated bona fide synthase activity with the native 15-carbon substrate farnesyl diphopshate (FPP) as well as with the 10-carbon substrate geranyl diphosphate (GPP). Reaction product analysis suggested that the GPP could be used to investigate early steps in the catalytic cascade of these enzymes. To investigate how structural features of the sesquiterpene synthases translate into enzymatic traits, a series of substrate and active site residue contacts maps were developed and used in a comparative approach to identify residues that might direct product specificity. The role and contribution of several of these residues to catalysis and product specificity were subsequently tested by the creation of site-directed mutants. One series of mutants was demonstrated to change the reaction product to a novel sesquiterpene, 4-epi-eremophilene, and while another series successfully transmutated TEAS into a HPS-like enzyme. This is the first report of a rational redesign of product specificity for any terpene synthase. The contact map provides a basis for the prediction of specific configurations of amino acids that might be necessary for as yet uncharacterized sesquiterpene synthases from natural sources. This prediction was tested by the subsequent isolation and validation that valencene synthase, a synthase from citrus, did indeed have the amino acid configuration as predicted. Lastly, an in vitro system was developed for analyzing the interaction between sesquiterpene synthases and the corresponding terpene hydroxylase. Development of this in vitro system is presented as a new important tool in further defining those biochemical features giving rise to the biological diversity of sesquiterpenes.
APA, Harvard, Vancouver, ISO, and other styles
2

Lehner, Bryan W. "Aggregation Pheromone Biosynthesis and Engineering in Plants for Stinkbug Pest Management." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/100605.

Full text
Abstract:
Stinkbugs (Pentatomidae) and other agricultural pests such as bark beetles and flea beetles are known to synthesize terpenoids as aggregation pheromones. Knowledge of the genes and enzymes involved in pheromone biosynthesis may allow engineering of pheromone biosynthetic pathways in plants to develop new forms of trap crops and agricultural practices for pest management. The harlequin bug, Murgantia histrionica, a specialist pest on crucifer crops, produces the sesquiterpene, murgantiol, as a male-specific aggregation pheromone. Similarly, the southern green stink bug, Nezara viridula, a generalist pest worldwide on soybean and other crops, releases sesquiterpene cis-/trans-(Z)-α-bisabolene epoxides as male-specific aggregation pheromone. In both species, enzymes called terpene synthases (TPSs) synthesize precursors of the aggregation pheromones, which are sesquipiperitol and (Z)-α-bisabolene as the precursor of murgantiol and cis-/trans-(Z)-α-bisabolene epoxide, respectively. We hypothesized that enzymes in the family of cytochrome P450 monooxygenases are involved in the conversion of these precursors to the final epoxide products. This study investigated the tissue specificity and sequence of these conversions by performing crude enzyme assays with protein extracts from male tissues. Furthermore, candidate P450 genes were selected by RNA-sequencing and co-expression analysis and the corresponding recombinant proteins tested for enzyme activity. To engineer the pheromone biosynthetic enzymes in plants, transient expression of the TPSs of both stink bugs was performed in Nicotiana benthamiana leaves. Both sesquipiperitol and (Z)-α-bisabolene were found to be produced and emitted from inoculated N. benthamiana leaves. Future work will implement stable transformation to engineer murgantiol biosynthesis in crucifer trap crops and develop similar approaches for pheromone engineering of other agricultural pests.
Master of Science
APA, Harvard, Vancouver, ISO, and other styles
3

Ly, Thuy Thi Bich [Verfasser], and Rita [Akademischer Betreuer] Bernhardt. "Characterization of CYP264B1 and a terpene cyclase of a terpene biosynthesis gene cluster from the myxobacterium Sorangium cellulosum So ce56 / Thuy Thi Bich Ly. Betreuer: Rita Bernhardt." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2011. http://d-nb.info/1057789291/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Molnar, Istvan, David Lopez, Jennifer Wisecaver, Timothy Devarenne, Taylor Weiss, Matteo Pellegrini, and Jeremiah Hackett. "Bio-crude transcriptomics: Gene discovery and metabolic network reconstruction for the biosynthesis of the terpenome of the hydrocarbon oil-producing green alga, Botryococcus braunii race B (Showa)*." BioMed Central, 2012. http://hdl.handle.net/10150/610020.

Full text
Abstract:
BACKGROUND:Microalgae hold promise for yielding a biofuel feedstock that is sustainable, carbon-neutral, distributed, and only minimally disruptive for the production of food and feed by traditional agriculture. Amongst oleaginous eukaryotic algae, the B race of Botryococcus braunii is unique in that it produces large amounts of liquid hydrocarbons of terpenoid origin. These are comparable to fossil crude oil, and are sequestered outside the cells in a communal extracellular polymeric matrix material. Biosynthetic engineering of terpenoid bio-crude production requires identification of genes and reconstruction of metabolic pathways responsible for production of both hydrocarbons and other metabolites of the alga that compete for photosynthetic carbon and energy.RESULTS:A de novo assembly of 1,334,609 next-generation pyrosequencing reads form the Showa strain of the B race of B. braunii yielded a transcriptomic database of 46,422 contigs with an average length of 756 bp. Contigs were annotated with pathway, ontology, and protein domain identifiers. Manual curation allowed the reconstruction of pathways that produce terpenoid liquid hydrocarbons from primary metabolites, and pathways that divert photosynthetic carbon into tetraterpenoid carotenoids, diterpenoids, and the prenyl chains of meroterpenoid quinones and chlorophyll. Inventories of machine-assembled contigs are also presented for reconstructed pathways for the biosynthesis of competing storage compounds including triacylglycerol and starch. Regeneration of S-adenosylmethionine, and the extracellular localization of the hydrocarbon oils by active transport and possibly autophagy are also investigated.CONCLUSIONS:The construction of an annotated transcriptomic database, publicly available in a web-based data depository and annotation tool, provides a foundation for metabolic pathway and network reconstruction, and facilitates further omics studies in the absence of a genome sequence for the Showa strain of B. braunii, race B. Further, the transcriptome database empowers future biosynthetic engineering approaches for strain improvement and the transfer of desirable traits to heterologous hosts.
APA, Harvard, Vancouver, ISO, and other styles
5

Weisberg, Alexandra Jamie. "Investigations into the molecular evolution of plant terpene, alkaloid, and urushiol biosynthetic enzymes." Diss., Virginia Tech, 2014. http://hdl.handle.net/10919/64408.

Full text
Abstract:
Plants produce a vast number of low-molecular-weight chemicals (so called secondary or specialized metabolites) that confer a selective advantage to the plant, such as defense against herbivory or protection from changing environmental conditions. Many of these specialized metabolites are used for their medicinal properties, as lead compounds in drug discovery, or to impart our food with different tastes and scents. These chemicals are produced by various pathways of enzyme-mediated reactions in plant cells. It is suspected that enzymes in plant specialized metabolism evolved from those in primary metabolism. Understanding how plants evolved to produce these diverse metabolites is of primary interest, as it can lead to the engineering of plants to be more resistant to both biotic and abiotic stress, or to produce more complex small molecule compounds that are difficult to derive. To that end, the first objective was to develop a schema for rational protein engineering using meta-analyses of a well-characterized sesquiterpene synthase family encoding two closely-related but different types of enzymes, using quantitative measures of natural selection on amino-acid positions previously demonstrated as important for neofunctionalization between two terpene synthase gene families. The change in the nonsynonymous to synonymous mutation rate ratio (dN/dS) between these two gene families was large at the sites known to be responsible for interconversion. This led to a metric (delta dN/dS) that might have some predictive power. This natural selection-oriented approach was tested on two related enzyme families involved in either nicotine/tropane alkaloid biosynthesis (putrescine N-methyltransferase) or primary metabolism (spermidine synthase) by attempting to interconvert a spermidine synthase to encode putrescine N-methyltransferase activity based upon past patterns of natural selection. In contrast to the HPS/TEAS system, using delta dN/dS metrics between SPDS and PMT and site directed mutagenesis of SPDS did not result in the desired neofunctionalization to PMT activity. Phylogenetic analyses were performed to investigate the molecular evolution of plant N-methyltransferases involved in three alkaloid biosynthetic pathways. The results from these studies indicated that unlike O-MTs that show monophyletic origins, plant N-MTs showed patterns indicating polyphyletic origins. To provide the foundation for future molecular-oriented studies of urushiol production in poison ivy, the complete poison ivy root and leaf transcriptomes were sequenced, assembled, and analyzed.
Ph. D.
APA, Harvard, Vancouver, ISO, and other styles
6

Barra, Lena [Verfasser]. "Studies on the Biosynthesis and Structure Elucidation of Terpene Natural Products by Isotopic Labeling Experiments / Lena Barra." Bonn : Universitäts- und Landesbibliothek Bonn, 2019. http://d-nb.info/1177881667/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Nagel, Raimund [Verfasser], Jonathan [Akademischer Betreuer] Gershenzon, Christian [Akademischer Betreuer] Hertweck, and Alain [Akademischer Betreuer] Tissier. "The regular function of isoprenyl diphosphate synthases in terpene biosynthesis / Raimund Nagel. Gutachter: Jonathan Gershenzon ; Christian Hertweck ; Alain Tissier." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2014. http://d-nb.info/105836037X/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Mondal, Prodyut [Verfasser], Jörg Gutachter] Degenhardt, Timo H. J. [Gutachter] [Niedermeyer, and Timothy Francis [Gutachter] Sharbel. "Biosynthesis and regulation of terpene production in accessions of chamomile (Matricaria recutita L.) / Prodyut Mondal ; Gutachter: Jörg Degenhardt, Timo H. J. Niedermeyer, Timothy Francis Sharbel." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2020. http://d-nb.info/1210732033/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Mondal, Prodyut [Verfasser], Jörg [Gutachter] Degenhardt, Timo H. J. [Gutachter] Niedermeyer, and Timothy Francis [Gutachter] Sharbel. "Biosynthesis and regulation of terpene production in accessions of chamomile (Matricaria recutita L.) / Prodyut Mondal ; Gutachter: Jörg Degenhardt, Timo H. J. Niedermeyer, Timothy Francis Sharbel." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:3:4-1981185920-330672.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Martinelli, Laure Marie Bernadette. "Étude de la biosynthèse des terpènes et de leur régulation chez Pelargonium x hybridum." Thesis, Lyon, 2020. http://www.theses.fr/2020LYSES010.

Full text
Abstract:
Le genre Pelargonium fait partie de la famille des Geraniaceae et réunit plus de 280 espèces, ainsi que de nombreux hybrides et variétés sélectionnés depuis le 18e siècle. Ces accessions regroupent notamment de pélargoniums commercialisés en tant que plantes ornementales (comme les P. x hortorum) mais également des pélargoniums odorants (comme les P. x hybridum cv rosat) qui sont cultivés pour leur huile essentielle (HE). L’HE de P. rosat est stockée dans des structures glandulaires (trichomes glandulaires) présentes sur les feuilles et se compose principalement de mono- et sesqui-terpénoïdes. Ces composés organiques volatils sont à l’origine du parfum « géranium », prisé des parfumeurs pour son profil olfactif complexe et rappelant l’odeur de rose. L’objectif de cette thèse était de mieux comprendre la diversité de terpénoïdes présents dans l’HE de pélargonium, de décrypter les mécanismes sous-jacents à la biosynthèse de ces nombreux composés odorants et plus particulièrement d’analyser les enzymes impliquées dans leur production. Afin de répondre à cet objectif, des études biochimiques et transcriptomiques ont été menées. Celles-ci ont permis de mettre en place une approche multi-omique afin d’étudier le terpénome de dix accessions de pélargoniums odorants, de caractériser structurellement et fonctionnellement des enzymes impliquées dans la biosynthèse de ce terpénome et d’analyser l’effet d’un stress climatique sur celui-ci
The Pelargonium genus belongs to the Geraniaceae family and includes more than 280 species as well as multiple hybrids and varieties, which have been selected by botanists since the 18th century. Among these accessions, several can be found on the market as ornemental plant (e.g. P. x hortorum) whereas some are cultivated for essential oil (EO) production (e.g. P. x hybridum cv rosat). P. rosat EO is stored in glandular trichomes from leaves and is mainly composed of mono- and sesqui-terpenoids. The resulting volatile organic compound mixture offers a characteristic “geranium” scent. Due to its sophisticated odour reminding of the rose scent, this scent is highly pursued by perfumers and fragrance industries. The purpose of this thesis was to improve our understanding of the terpenoid diversity in pelargonium EO and decipher mechanims underlying their biosynthesis, in particular by characterising enzymes responsible for their production. To this aim, biochemical and transcriptomic studies have been performed. Therefore, a multi-omic approach has been implemented to analyse the terpenome from ten scented-pelargoniums. Moreover, structural and functional analysis of several enzymes involved in terpenoid biosynthesis have been performed and the effect of a climatic stress on the EO composition has been studied
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Terpene biosynthesis"

1

Medicinal natural products: A biosynthetic approach. 3rd ed. Hoboken: Wiley, 2008.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Medicinal natural products: A biosynthetic approach. Chichester [England]: Wiley, 1997.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

The way of synthesis: Evolution of design and methods for natural products. Weinheim, DE: Wiley-VCH, 2007.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Bjarke, Albin. Terpenes: Biosynthesis, Applications and Research. Nova Science Publishers, Incorporated, 2018.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Bates, Alanna R. Terpenoids and Squalene: Biosynthesis, Functions and Health Implications. Nova Science Publishers, Incorporated, 2015.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Dewick, Paul M. Medicinal Natural Products: A Biosynthetic Approach. Not Avail, 2004.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

Medicinal Natural Products: A Biosynthetic Approach. John Wiley & Sons, 2001.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Medicinal Natural Products: A Biosynthetic Approach. 2nd ed. Wiley, 2002.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

1951-, Taylor Peter G., Royal Society of Chemistry (Great Britain), and Open University, eds. Mechanism and synthesis. Cambridge: Royal Society of Chemistry, 2002.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

Taylor, P. G. Mechanism and Synthesis. Royal Society of Chemistry, 2002.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Terpene biosynthesis"

1

Lichtenthaler, Hartmut K., and Johannes G. Zeidler. "Isoprene and terpene biosynthesis." In Tree Physiology, 79–99. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-015-9856-9_4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Cheniclet, C., C. Bernard-Dagan, and G. Pauly. "Terpene Biosynthesis Under Pathological Conditions." In Mechanisms of Woody Plant Defenses Against Insects, 117–30. New York, NY: Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3828-7_6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Pengelly, Andrew. "Terpenes." In The constituents of medicinal plants, 73–94. 3rd ed. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789243079.0005.

Full text
Abstract:
Abstract This chapter provides an overview of the various structures and biosynthesis and biosynthetic pathways of terpenes and terpenoids (terpenes with oxygen) from medicinal plants, such as Ginkgo biloba, Picrorhiza kurroa, Rehmannia glutinosa, olives and ginger, among others.
APA, Harvard, Vancouver, ISO, and other styles
4

Zerbe, Philipp, and Jörg Bohlmann. "Bioproducts, Biofuels, and Perfumes: Conifer Terpene Synthases and their Potential for Metabolic Engineering." In Phytochemicals – Biosynthesis, Function and Application, 85–107. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04045-5_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Breitmaier, Eberhard. "Terpene, Bedeutung, Bauprinzip, Biosynthese." In Terpene, 11–19. Wiesbaden: Vieweg+Teubner Verlag, 1999. http://dx.doi.org/10.1007/978-3-322-94727-7_1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Herbert, R. B. "Terpenes and steroids." In The Biosynthesis of Secondary Metabolites, 63–95. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-010-9132-9_4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Ishihara, Kazuaki. "Higher Terpenes and Steroids." In From Biosynthesis to Total Synthesis, 296–330. Hoboken, NJ: John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118754085.ch9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Ibdah, Mwafaq, Andrew Muchlinski, Mossab Yahyaa, Bhagwat Nawade, and Dorothea Tholl. "Carrot Volatile Terpene Metabolism: Terpene Diversity and Biosynthetic Genes." In The Carrot Genome, 279–93. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03389-7_16.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Alonso, William R., and Rodney Croteau. "Comparison of Two Monoterpene Cyclases Isolated from Higher Plants; γ-Terpinene Synthase from Thymus Vulgaris, and Limonene Synthase from Mentha x Piperita." In Secondary-Metabolite Biosynthesis and Metabolism, 239–51. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3012-1_16.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Abraham, W. R. "Biosynthetic Oils, Fats, Terpenes, Sterols, Waxes: Analytical Methods, Diversity, Characteristics." In Handbook of Hydrocarbon and Lipid Microbiology, 79–95. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-77587-4_4.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Terpene biosynthesis"

1

Ștefan, G.-A., M.-M. Zamfirache, and LD Gorgan. "Expression profile of three genes involved in terpene biosynthesis in Lavandula angustifolia cultivars." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399781.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Terpene biosynthesis' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography