Academic literature on the topic 'Terpene biosynthesis'

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Journal articles on the topic "Terpene biosynthesis"

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Sayari, Mohammad, Magrieta A. van der Nest, Emma T. Steenkamp, Saleh Rahimlou, Almuth Hammerbacher, and Brenda D. Wingfield. "Characterization of the Ergosterol Biosynthesis Pathway in Ceratocystidaceae." Journal of Fungi 7, no. 3 (2021): 237. http://dx.doi.org/10.3390/jof7030237.

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Terpenes represent the biggest group of natural compounds on earth. This large class of organic hydrocarbons is distributed among all cellular organisms, including fungi. The different classes of terpenes produced by fungi are mono, sesqui, di- and triterpenes, although triterpene ergosterol is the main sterol identified in cell membranes of these organisms. The availability of genomic data from members in the Ceratocystidaceae enabled the detection and characterization of the genes encoding the enzymes in the mevalonate and ergosterol biosynthetic pathways. Using a bioinformatics approach, fu
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Chekan, Jonathan R., Shaun M. K. McKinnie, Joseph P. Noel, and Bradley S. Moore. "Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into anN-prenyltransferase." Proceedings of the National Academy of Sciences 117, no. 23 (2020): 12799–805. http://dx.doi.org/10.1073/pnas.2001325117.

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Prenylation is a common biological reaction in all domains of life wherein prenyl diphosphate donors transfer prenyl groups onto small molecules as well as large proteins. The enzymes that catalyze these reactions are structurally distinct from ubiquitous terpene cyclases that, instead, assemble terpenes via intramolecular rearrangements of a single substrate. Herein, we report the structure and molecular details of a new family of prenyltransferases from marine algae that repurposes the terpene cyclase structural fold for theN-prenylation of glutamic acid during the biosynthesis of the potent
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Helfrich, Eric J. N., Geng-Min Lin, Christopher A. Voigt, and Jon Clardy. "Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering." Beilstein Journal of Organic Chemistry 15 (November 29, 2019): 2889–906. http://dx.doi.org/10.3762/bjoc.15.283.

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Terpenoids are the largest and structurally most diverse class of natural products. They possess potent and specific biological activity in multiple assays and against diseases, including cancer and malaria as notable examples. Although the number of characterized terpenoid molecules is huge, our knowledge of how they are biosynthesized is limited, particularly when compared to the well-studied thiotemplate assembly lines. Bacteria have only recently been recognized as having the genetic potential to biosynthesize a large number of complex terpenoids, but our current ability to associate genet
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Kemper, Katarina, Max Hirte, Markus Reinbold, Monika Fuchs, and Thomas Brück. "Opportunities and challenges for the sustainable production of structurally complex diterpenoids in recombinant microbial systems." Beilstein Journal of Organic Chemistry 13 (May 8, 2017): 845–54. http://dx.doi.org/10.3762/bjoc.13.85.

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With over 50.000 identified compounds terpenes are the largest and most structurally diverse group of natural products. They are ubiquitous in bacteria, plants, animals and fungi, conducting several biological functions such as cell wall components or defense mechanisms. Industrial applications entail among others pharmaceuticals, food additives, vitamins, fragrances, fuels and fuel additives. Central building blocks of all terpenes are the isoprenoid compounds isopentenyl diphosphate and dimethylallyl diphosphate. Bacteria like Escherichia coli harbor a native metabolic pathway for these isop
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Wang, Xin, Wei Liu, Changpeng Xin, et al. "Enhanced limonene production in cyanobacteria reveals photosynthesis limitations." Proceedings of the National Academy of Sciences 113, no. 50 (2016): 14225–30. http://dx.doi.org/10.1073/pnas.1613340113.

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Terpenes are the major secondary metabolites produced by plants, and have diverse industrial applications as pharmaceuticals, fragrance, solvents, and biofuels. Cyanobacteria are equipped with efficient carbon fixation mechanism, and are ideal cell factories to produce various fuel and chemical products. Past efforts to produce terpenes in photosynthetic organisms have gained only limited success. Here we engineered the cyanobacterium Synechococcus elongatus PCC 7942 to efficiently produce limonene through modeling guided study. Computational modeling of limonene flux in response to photosynth
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Agliassa, Chiara, and Massimo Maffei. "Origanum vulgare Terpenoids Induce Oxidative Stress and Reduce the Feeding Activity of Spodoptera littoralis." International Journal of Molecular Sciences 19, no. 9 (2018): 2805. http://dx.doi.org/10.3390/ijms19092805.

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Terpenoids are toxic compounds produced by plants as a defense strategy against insect herbivores. We tested the effect of Origanum vulgare terpenoids on the generalist herbivore Spodoptera littoralis and the response of the plant to herbivory. Terpenoids were analyzed by GC-FID and GC-MS and quantitative gene expression (qPCR) was evaluated on selected plant genes involved in both terpene biosynthesis. The insect detoxification response to terpenes was evaluated by monitoring antioxidant enzymes activity and expression of insect genes involved in terpene detoxification. O. vulgare terpenoid b
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He, Xueying, Huan Wang, Jinfen Yang, Ke Deng, and Teng Wang. "RNA sequencing on Amomum villosum Lour. induced by MeJA identifies the genes of WRKY and terpene synthases involved in terpene biosynthesis." Genome 61, no. 2 (2018): 91–102. http://dx.doi.org/10.1139/gen-2017-0142.

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Amomum villosum Lour. is an important Chinese medicinal plant that has diverse medicinal functions, and mainly contains volatile terpenes. This study aims to explore the WRKY transcription factors (TFs) and terpene synthase (TPS) unigenes that might be involved in terpene biosynthesis in A. villosum, and thus providing some new information on the regulation of terpenes in plants. RNA sequencing of A. villosum induced by methyl jasmonate (MeJA) revealed that the WRKY family was the second largest TF family in the transcriptome. Thirty-six complete WRKY domain sequences were expressed in respons
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Oldfield, Eric, and Fu-Yang Lin. "Terpene Biosynthesis: Modularity Rules." Angewandte Chemie International Edition 51, no. 5 (2011): 1124–37. http://dx.doi.org/10.1002/anie.201103110.

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Lancaster, Jason, Ashot Khrimian, Sharon Young, et al. "De novo formation of an aggregation pheromone precursor by an isoprenyl diphosphate synthase-related terpene synthase in the harlequin bug." Proceedings of the National Academy of Sciences 115, no. 37 (2018): E8634—E8641. http://dx.doi.org/10.1073/pnas.1800008115.

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Insects use a diverse array of specialized terpene metabolites as pheromones in intraspecific interactions. In contrast to plants and microbes, which employ enzymes called terpene synthases (TPSs) to synthesize terpene metabolites, limited information from few species is available about the enzymatic mechanisms underlying terpene pheromone biosynthesis in insects. Several stink bugs (Hemiptera: Pentatomidae), among them severe agricultural pests, release 15-carbon sesquiterpenes with a bisabolene skeleton as sex or aggregation pheromones. The harlequin bug, Murgantia histrionica, a specialist
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Ichikawa, Yoshiyasu, Toshiki Yamasaki, Keisuke Nakanishi, Yutaro Udagawa, Seijiro Hosokawa, and Toshiya Masuda. "Bioinspired Synthesis of the Central Core of Halichonadin H: The Passerini Reaction in a Hypothetical Biosynthesis of Marine Natural Products." Synthesis 51, no. 11 (2019): 2305–10. http://dx.doi.org/10.1055/s-0037-1610867.

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A pathway is proposed for the biosynthesis of the unique homodimeric terpene, halichonadin H. The proposed biosynthetic pathway involves two key Passerini reactions of eudesmane-type terpene isocyanides. The Passerini reaction of a model terpene isocyanide and formaldehyde afforded an α-hydroxy acetamide, which was further subjected to oxidation and a second Passerini reaction. This reaction sequence furnished an α-hydroxy malonamide connected with two identical terpene units which is the identical structural motif found in halichonadin H.
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Dissertations / Theses on the topic "Terpene biosynthesis"

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Greenhagen, Bryan T. "ORIGINS OF ISOPRENOID DIVERSITY: A STUDY OF STRUCTURE-FUNCTION RELATIONSHIPS IN SESQUITERPENE SYNTHASES." UKnowledge, 2003. http://uknowledge.uky.edu/gradschool_diss/440.

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Plant sesquiterpene synthases catalyze the conversion of the linear substrate farnesyl diphosphate, FPP, into a remarkable array of secondary metabolites. These secondary metabolites in turn mediate a number of important interactions between plants and their environment, such as plant-plant, plant-insect and plant-pathogen interactions. Given the relative biological importance of sesquiterpenes and their use in numerous practical applications, the current thesis was directed towards developing a better understanding of the mechanisms employed by sesquiterpene synthases in the biosynthesis of s
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Lehner, Bryan W. "Aggregation Pheromone Biosynthesis and Engineering in Plants for Stinkbug Pest Management." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/100605.

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Stinkbugs (Pentatomidae) and other agricultural pests such as bark beetles and flea beetles are known to synthesize terpenoids as aggregation pheromones. Knowledge of the genes and enzymes involved in pheromone biosynthesis may allow engineering of pheromone biosynthetic pathways in plants to develop new forms of trap crops and agricultural practices for pest management. The harlequin bug, Murgantia histrionica, a specialist pest on crucifer crops, produces the sesquiterpene, murgantiol, as a male-specific aggregation pheromone. Similarly, the southern green stink bug, Nezara viridula, a gener
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Ly, Thuy Thi Bich [Verfasser], and Rita [Akademischer Betreuer] Bernhardt. "Characterization of CYP264B1 and a terpene cyclase of a terpene biosynthesis gene cluster from the myxobacterium Sorangium cellulosum So ce56 / Thuy Thi Bich Ly. Betreuer: Rita Bernhardt." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2011. http://d-nb.info/1057789291/34.

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Molnar, Istvan, David Lopez, Jennifer Wisecaver, et al. "Bio-crude transcriptomics: Gene discovery and metabolic network reconstruction for the biosynthesis of the terpenome of the hydrocarbon oil-producing green alga, Botryococcus braunii race B (Showa)*." BioMed Central, 2012. http://hdl.handle.net/10150/610020.

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BACKGROUND:Microalgae hold promise for yielding a biofuel feedstock that is sustainable, carbon-neutral, distributed, and only minimally disruptive for the production of food and feed by traditional agriculture. Amongst oleaginous eukaryotic algae, the B race of Botryococcus braunii is unique in that it produces large amounts of liquid hydrocarbons of terpenoid origin. These are comparable to fossil crude oil, and are sequestered outside the cells in a communal extracellular polymeric matrix material. Biosynthetic engineering of terpenoid bio-crude production requires identification of genes a
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Weisberg, Alexandra Jamie. "Investigations into the molecular evolution of plant terpene, alkaloid, and urushiol biosynthetic enzymes." Diss., Virginia Tech, 2014. http://hdl.handle.net/10919/64408.

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Plants produce a vast number of low-molecular-weight chemicals (so called secondary or specialized metabolites) that confer a selective advantage to the plant, such as defense against herbivory or protection from changing environmental conditions. Many of these specialized metabolites are used for their medicinal properties, as lead compounds in drug discovery, or to impart our food with different tastes and scents. These chemicals are produced by various pathways of enzyme-mediated reactions in plant cells. It is suspected that enzymes in plant specialized metabolism evolved from those in pri
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Barra, Lena [Verfasser]. "Studies on the Biosynthesis and Structure Elucidation of Terpene Natural Products by Isotopic Labeling Experiments / Lena Barra." Bonn : Universitäts- und Landesbibliothek Bonn, 2019. http://d-nb.info/1177881667/34.

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Nagel, Raimund [Verfasser], Jonathan [Akademischer Betreuer] Gershenzon, Christian [Akademischer Betreuer] Hertweck, and Alain [Akademischer Betreuer] Tissier. "The regular function of isoprenyl diphosphate synthases in terpene biosynthesis / Raimund Nagel. Gutachter: Jonathan Gershenzon ; Christian Hertweck ; Alain Tissier." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2014. http://d-nb.info/105836037X/34.

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Mondal, Prodyut [Verfasser], Jörg Gutachter] Degenhardt, Timo H. J. [Gutachter] [Niedermeyer, and Timothy Francis [Gutachter] Sharbel. "Biosynthesis and regulation of terpene production in accessions of chamomile (Matricaria recutita L.) / Prodyut Mondal ; Gutachter: Jörg Degenhardt, Timo H. J. Niedermeyer, Timothy Francis Sharbel." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2020. http://d-nb.info/1210732033/34.

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Mondal, Prodyut [Verfasser], Jörg [Gutachter] Degenhardt, Timo H. J. [Gutachter] Niedermeyer, and Timothy Francis [Gutachter] Sharbel. "Biosynthesis and regulation of terpene production in accessions of chamomile (Matricaria recutita L.) / Prodyut Mondal ; Gutachter: Jörg Degenhardt, Timo H. J. Niedermeyer, Timothy Francis Sharbel." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:3:4-1981185920-330672.

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Martinelli, Laure Marie Bernadette. "Étude de la biosynthèse des terpènes et de leur régulation chez Pelargonium x hybridum." Thesis, Lyon, 2020. http://www.theses.fr/2020LYSES010.

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Le genre Pelargonium fait partie de la famille des Geraniaceae et réunit plus de 280 espèces, ainsi que de nombreux hybrides et variétés sélectionnés depuis le 18e siècle. Ces accessions regroupent notamment de pélargoniums commercialisés en tant que plantes ornementales (comme les P. x hortorum) mais également des pélargoniums odorants (comme les P. x hybridum cv rosat) qui sont cultivés pour leur huile essentielle (HE). L’HE de P. rosat est stockée dans des structures glandulaires (trichomes glandulaires) présentes sur les feuilles et se compose principalement de mono- et sesqui-terpénoïdes.
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Books on the topic "Terpene biosynthesis"

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Medicinal natural products: A biosynthetic approach. 3rd ed. Wiley, 2008.

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Medicinal natural products: A biosynthetic approach. Wiley, 1997.

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The way of synthesis: Evolution of design and methods for natural products. Wiley-VCH, 2007.

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Bjarke, Albin. Terpenes: Biosynthesis, Applications and Research. Nova Science Publishers, Incorporated, 2018.

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Bates, Alanna R. Terpenoids and Squalene: Biosynthesis, Functions and Health Implications. Nova Science Publishers, Incorporated, 2015.

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Dewick, Paul M. Medicinal Natural Products: A Biosynthetic Approach. Not Avail, 2004.

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Medicinal Natural Products: A Biosynthetic Approach. John Wiley & Sons, 2001.

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Medicinal Natural Products: A Biosynthetic Approach. 2nd ed. Wiley, 2002.

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1951-, Taylor Peter G., Royal Society of Chemistry (Great Britain), and Open University, eds. Mechanism and synthesis. Royal Society of Chemistry, 2002.

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Taylor, P. G. Mechanism and Synthesis. Royal Society of Chemistry, 2002.

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Book chapters on the topic "Terpene biosynthesis"

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Lichtenthaler, Hartmut K., and Johannes G. Zeidler. "Isoprene and terpene biosynthesis." In Tree Physiology. Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-015-9856-9_4.

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Cheniclet, C., C. Bernard-Dagan, and G. Pauly. "Terpene Biosynthesis Under Pathological Conditions." In Mechanisms of Woody Plant Defenses Against Insects. Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3828-7_6.

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Pengelly, Andrew. "Terpenes." In The constituents of medicinal plants, 3rd ed. CABI, 2021. http://dx.doi.org/10.1079/9781789243079.0005.

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Abstract This chapter provides an overview of the various structures and biosynthesis and biosynthetic pathways of terpenes and terpenoids (terpenes with oxygen) from medicinal plants, such as Ginkgo biloba, Picrorhiza kurroa, Rehmannia glutinosa, olives and ginger, among others.
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Zerbe, Philipp, and Jörg Bohlmann. "Bioproducts, Biofuels, and Perfumes: Conifer Terpene Synthases and their Potential for Metabolic Engineering." In Phytochemicals – Biosynthesis, Function and Application. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04045-5_5.

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Breitmaier, Eberhard. "Terpene, Bedeutung, Bauprinzip, Biosynthese." In Terpene. Vieweg+Teubner Verlag, 1999. http://dx.doi.org/10.1007/978-3-322-94727-7_1.

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Herbert, R. B. "Terpenes and steroids." In The Biosynthesis of Secondary Metabolites. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-010-9132-9_4.

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Ishihara, Kazuaki. "Higher Terpenes and Steroids." In From Biosynthesis to Total Synthesis. John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118754085.ch9.

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Ibdah, Mwafaq, Andrew Muchlinski, Mossab Yahyaa, Bhagwat Nawade, and Dorothea Tholl. "Carrot Volatile Terpene Metabolism: Terpene Diversity and Biosynthetic Genes." In The Carrot Genome. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03389-7_16.

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Alonso, William R., and Rodney Croteau. "Comparison of Two Monoterpene Cyclases Isolated from Higher Plants; γ-Terpinene Synthase from Thymus Vulgaris, and Limonene Synthase from Mentha x Piperita." In Secondary-Metabolite Biosynthesis and Metabolism. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3012-1_16.

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Abraham, W. R. "Biosynthetic Oils, Fats, Terpenes, Sterols, Waxes: Analytical Methods, Diversity, Characteristics." In Handbook of Hydrocarbon and Lipid Microbiology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-77587-4_4.

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Conference papers on the topic "Terpene biosynthesis"

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Ștefan, G.-A., M.-M. Zamfirache, and LD Gorgan. "Expression profile of three genes involved in terpene biosynthesis in Lavandula angustifolia cultivars." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399781.

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