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1

Lai, Shih-Ming, I.-Wen Chen, and Ming-Jyi Tsai. "Preparative isolation of terpene trilactones from Ginkgo biloba leaves." Journal of Chromatography A 1092, no. 1 (2005): 125–34. http://dx.doi.org/10.1016/j.chroma.2005.01.028.

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2

Trapp, Susan C., and Rodney B. Croteau. "Genomic Organization of Plant Terpene Synthases and Molecular Evolutionary Implications." Genetics 158, no. 2 (2001): 811–32. http://dx.doi.org/10.1093/genetics/158.2.811.

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Abstract Terpenoids are the largest, most diverse class of plant natural products and they play numerous functional roles in primary metabolism and in ecological interactions. The first committed step in the formation of the various terpenoid classes is the transformation of the prenyl diphosphate precursors, geranyl diphosphate, farnesyl diphosphate, and geranylgeranyl diphosphate, to the parent structures of each type catalyzed by the respective monoterpene (C10), sesquiterpene (C15), and diterpene synthases (C20). Over 30 cDNAs encoding plant terpenoid synthases involved in primary and seco
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3

Coleman, W. M., Bert M. Gordon, and Brian M. Lawrence. "Examinations of the Matrix Isolation Fourier Transform Infrared Spectra of Organic Compounds: Part XII." Applied Spectroscopy 43, no. 2 (1989): 298–304. http://dx.doi.org/10.1366/0003702894203273.

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Matrix isolation Fourier transform infrared spectra (MI/FT-IR), mass spectra (MS), carbon-13 Nuclear Magnetic Resonance (13C-NMR) spectra, condensed-phase infrared spectra, and vapor-phase infrared (IR) spectra are presented for a series of terpene compounds. Subtle differences in positional and configurational isomers commonly found with terpenes could be easily detected by the MI/FT-IR spectra. The results are comparable in some aspects to those obtainable from 13C-NMR and thin-film IR; however, most importantly, they are acquired at the low nanogram level for MI/FT-IR, as compared to the mi
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4

Yang, Chang-Qing, Xiu-Ming Wu, Ju-Xin Ruan, et al. "Isolation and characterization of terpene synthases in cotton (Gossypium hirsutum)." Phytochemistry 96 (December 2013): 46–56. http://dx.doi.org/10.1016/j.phytochem.2013.09.009.

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5

Awakawa, Takayoshi. "Enzymatic reactions in teleocidin B biosynthesis." Journal of Natural Medicines 75, no. 3 (2021): 467–74. http://dx.doi.org/10.1007/s11418-021-01504-2.

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AbstractThe teleocidin B family members are terpene indole compounds isolated from Streptomyces bacteria, and they strongly activate protein kinase C (PKC). Their unique structures have attracted many researchers in the natural product chemistry and pharmacology fields, and numerous isolation and bioactivity studies have been conducted. The accumulated information has facilitated the identification of the enzymatic reactions in teleocidin biosynthesis, and new developments in structural biology have strongly aided efforts to clarify the finer points of these reactions. This review describes th
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Weiss, Eve R., Jana Pika, and Robert J. Braddock. "Isolation and Identification of Terpene Chlorohydrins Found in Cold-Pressed Orange Oil." Journal of Agricultural and Food Chemistry 51, no. 8 (2003): 2277–82. http://dx.doi.org/10.1021/jf026122n.

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7

Wang, Piao-Yi, Rong Ni, Ting-Ting Zhu, et al. "Isolation and functional characterization of four microbial type terpene synthases from ferns." Plant Physiology and Biochemistry 155 (October 2020): 716–24. http://dx.doi.org/10.1016/j.plaphy.2020.08.037.

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8

Hattan, Jun-ichiro, Kazutoshi Shindo, Tetsuya Sasaki, and Norihiko Misawa. "Isolation and Functional Characterization of New Terpene Synthase Genes from Traditional Edible Plants." Journal of Oleo Science 67, no. 10 (2018): 1235–46. http://dx.doi.org/10.5650/jos.ess18163.

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9

Jasiem, Thamer Mouhi. "Isolation of terpene and pharmacognostical study of iraqi caper shrubs (Capparis spinosa) L." Research Journal of Pharmacy and Technology 11, no. 6 (2018): 2388. http://dx.doi.org/10.5958/0974-360x.2018.00441.9.

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10

French, Larry G. "Isolation and Structure Elucidation of the Terpene β-Thujone from Cedar Leaf Oil". Journal of Chemical Education 88, № 6 (2011): 829–31. http://dx.doi.org/10.1021/ed100620b.

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11

Weyerstahl, Peter, Helga Marschall-Weyerstahl, Martin Schröder, and Vijay K. Kaul. "Terpenes and terpene derivatives, XXIV. Isolation and stereochemistry of the four artedouglasia oxides." Liebigs Annalen der Chemie 1988, no. 9 (1988): 917–18. http://dx.doi.org/10.1002/jlac.198819880919.

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12

de Mesquita, Mariana L., José E. de Paula, Laila S. Espindola, et al. "Protoflavanones from the Wood Stem of Salvertia convallariodora." Natural Product Communications 12, no. 4 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200413.

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Phytochemical analysis of the ethyl acetate extract of stem wood of Salvertia convallariodora A. St.-Hil. (Vochysiaceae), a Brazilian Cerrado species, led to the isolation and full characterization of three new non-aromatic B-ring flavanones (1-3) as well as the terpene mixture of sericic acid (4), 24-hydroxytormentic acid (5), 24-hydroxytormentic acid glucosyl ester (6), and sericoside (7), all identified for the first time from S. convallariodora. The structures of the new flavanones (1-3) were established from IR, LC-PDA-qTOF-MS, and NMR spectral data, including 2D NMR experiments.
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13

Atolani, Olubunmi, and Gabriel A. Olatunji. "Isolation and evaluation of antiglycation potential of polyalthic acid (furano-terpene) from Daniella oliveri." Journal of Pharmaceutical Analysis 4, no. 6 (2014): 407–11. http://dx.doi.org/10.1016/j.jpha.2014.05.002.

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14

Okoth, Dorothy A., Joachim J. Hug, Ronald Garcia, Cathrin Spröer, Jörg Overmann, and Rolf Müller. "2-Hydroxysorangiadenosine: Structure and Biosynthesis of a Myxobacterial Sesquiterpene–Nucleoside." Molecules 25, no. 11 (2020): 2676. http://dx.doi.org/10.3390/molecules25112676.

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Myxobacteria represent an under-investigated source for biologically active natural products featuring intriguing structural moieties with potential applications, e.g., in the pharmaceutical industry. Sorangiadenosine and the here-discovered 2-hydroxysorangiadenosine are myxobacterial sesquiterpene–nucleosides with an unusual structural moiety, a bicyclic eudesmane-type sesquiterpene. As the biosynthesis of these rare terpene–nucleoside hybrid natural products remains elusive, we investigated secondary metabolomes and genomes of several 2-hydroxysorangiadenosine-producing myxobacteria. We repo
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15

Прокопчук (Prokopchuk), Денис (Denis) Игоревич (Igorevich), Олег (Oleg) Игоревич (Igorevich) Покровский (Pokrovskiy), Ольга (Ol'ga) Олеговна (Olegovna) Паренаго (Parenago), et al. "COMPARISON OF THE QUALITATIVE COMPOSITION OF LAURUS NOBILIS LEAVES EXTRACTS OBTAINED BY SUPERCRITICAL FLUID EXTRACTION AND MICROWAVE-ASSISTED EXTRACTION." chemistry of plant raw material, no. 3 (March 20, 2018): 169–77. http://dx.doi.org/10.14258/jcprm.2018033758.

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Along with traditional methods for processing aroma plants, such as steam distillation or extraction with organic solvents, novel alternative approaches are developed which provide the means for a more effective isolation of biologically active compounds from plant matrices and simultaneously possess ecological attractiveness. Supercritical fluid extraction and microwave-assisted extraction can be attributed to such approaches. Their implementation into routine practice is partially hampered by somewhat vague understanding of applicability areas of these methods as well as by the lack of knowl
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16

Kung, Chen, Chao, Wu, Lin, and Chen. "Analysis of Volatile Constituents in Platostoma palustre (Blume) Using Headspace Solid-Phase Microextraction and Simultaneous Distillation-Extraction." Foods 8, no. 9 (2019): 415. http://dx.doi.org/10.3390/foods8090415.

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Hsian-tsao (Platostoma palustre Blume) is a traditional Taiwanese food. It is admired by many consumers, especially in summer, because of its aroma and taste. This study reports the analysis of the volatile components present in eight varieties of Hsian-tsao using headspace solid-phase microextraction (HS-SPME) and simultaneous distillation-extraction (SDE) coupled with gas chromatography (GC) and gas chromatography-mass spectrometry (GC/MS). HS-SPME is a non-heating method, and the results show relatively true values of the samples during flavor isolation. However, it is a kind of headspace a
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17

J. Fradi, Ahmed. "Evaluation the Effectiveness of Different Concentrations Phenols, Alkaloids and Terpenes Extracted from Pimpinella anisum against Phytophthora Fungi." Ibn AL- Haitham Journal For Pure and Applied Sciences 35, no. 2 (2022): 1–6. http://dx.doi.org/10.30526/35.2.2746.

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This study did the isolation, purification, and identification of the fungus Phytophthora cinnamomi of some infected plants, including Chili pepper, cucumber, and eggplant. The green parts of Pimpinella anisum plant were grounded to a semi-powdered state. Phenols, alkaloids and terpenes were extracted from this plant, then the anti-fungal activity was evaluated at different concentrations of 5% and 10%. The percentage of radial growth inhibition of fungi with plant extracts was measured after seven days of incubation. The results showed that the terpene extract was the most effective against f
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18

Garson, Mary J., Annette F. Dexter, Lynette K. Lambert, and Vicky Liokas. "Isolation of the Bioactive Terpene 7-Deacetoxy-olepupuane from the Temperate Marine Spong Dysidea Sp." Journal of Natural Products 55, no. 3 (1992): 364–67. http://dx.doi.org/10.1021/np50081a013.

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19

Sulastri, Lilik, Ristanti Mega Lestari, and Partomuan Simanjuntak. "Isolasi Dan Identifikasi Senyawa Kimia Monoterpen Dari Fraksi Etilasetat Daun Keji Beling (Strobilanthes crispa (L.) Blume) Yang Mempunyai Daya Sitotoksik." Jurnal Fitofarmaka Indonesia 8, no. 1 (2021): 12–17. http://dx.doi.org/10.33096/jffi.v8i1.721.

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Isolation and identification one of chemical compound mono-terpene from Keji beling plant (local name) (Strobilanthes crispa) has been done. Extraction was carried out by maceration of the keji beling leaf powder with ethanol 96%, then partitioned with water-ethyl acetate. Ethylacetate extract was isolated and purified by a cytotoxic guide fractionation system with Brine Shrimp Lethality Test (BSLT) on column chromatography (SiO2; n-hexane - ethylacetate = 20 : 1); and preparative Thin Layer Chromatography (TLC) (SiO2; n-hexane - ethylaseate = 10 : 1) which gave one compound in oily form. Base
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20

Katavic, Peter L., Pinus Jumaryatno, John N. A. Hooper, Joanne T. Blanchfield, and Mary J. Garson. "Oxygenated Terpenoids from the Australian Sponges Coscinoderma matthewsi and Dysidea sp., and the Nudibranch Chromodoris albopunctata." Australian Journal of Chemistry 65, no. 5 (2012): 531. http://dx.doi.org/10.1071/ch12010.

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The isolation and structure elucidation of seven new oxygenated terpenoids and eight known terpene metabolites from marine invertebrates collected at the Inner Gneerings Reef, South East Queensland, is discussed. Investigation of the sponge Coscinoderma matthewsi yielded an epoxylactone derivative (1) of the known furanoterpene tetradehydrofurospongin-1 (2). A chemical investigation of the dissected nudibranch Chromodoris albopunctata provided the new oxygenated diterpenes 12α-acetoxyspongian-16-one (10), 20-acetoxyspongian-16-one (12), 20-oxyspongian-16-one propionate (13) and 12α,20-dioxyspo
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Katavic, Peter L., Pinus Jumaryatno, John N. A. Hooper, Joanne T. Blanchfield, and Mary J. Garson. "Note of clarification about: Oxygenated Terpenoids from the Australian Sponges Coscinoderma matthewsi and Dysidea sp., and the Nudibranch Chromodoris albopunctata [vol. 65, pp. 531–538]." Australian Journal of Chemistry 66, no. 11 (2013): 1461. http://dx.doi.org/10.1071/ch12010_nc.

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The isolation and structure elucidation of seven new oxygenated terpenoids and eight known terpene metabolites from marine invertebrates collected at the Inner Gneerings Reef, South East Queensland, is discussed. Investigation of the sponge Coscinoderma matthewsi yielded an epoxylactone derivative (1) of the known furanoterpene tetradehydrofurospongin-1 (2). A chemical investigation of the dissected nudibranch Chromodoris albopunctata provided the new oxygenated diterpenes 12?-acetoxyspongian-16-one (10), 20-acetoxyspongian-16-one (12), 20-oxyspongian-16-one propionate (13) and 12?,20-dioxyspo
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22

Li, Huanhuan, Hongji Li, Shuo Chen, Wenhui Wu, and Peng Sun. "Isolation and Identification of Pentalenolactone Analogs from Streptomyces sp. NRRL S-4." Molecules 26, no. 23 (2021): 7377. http://dx.doi.org/10.3390/molecules26237377.

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Terpene synthases are widely distributed in Actinobacteria. Genome sequencing of Streptomyces sp. NRRL S-4 uncovered a biosynthetic gene cluster (BGC) that putatively synthesizes pentalenolactone type terpenes. Guided by genomic information, the S-4 strain was chemically investigated, resulting in the isolation of two new sesquiterpenoids, 1-deoxy-8α-hydroxypentalenic acid (1) and 1-deoxy-9β-hydroxy-11-oxopentalenic acid (2), as shunt metabolites of the pentalenolactone (3) biosynthesis pathway. Their structures and absolute configurations were elucidated by analyses of HRESIMS and NMR spectro
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23

Yuping, Tang, and Lou Fengchang. "SEPARATION AND ISOLATION OF TERPENE LACTONES FROM GINKGO BILOBA L. BY DIRECT HIGH PERFORMANCE LIQUID CHROMATOGRAPHY." Journal of Liquid Chromatography & Related Technologies 23, no. 18 (2000): 2897–900. http://dx.doi.org/10.1081/jlc-100101241.

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24

Suciati, Lynette K. Lambert, Benjamin P. Ross, Myrna A. Deseo, and Mary J. Garson. "Phytochemical Study of Fagraea spp. Uncovers a New Terpene Alkaloid with Anti-Inflammatory Properties." Australian Journal of Chemistry 64, no. 4 (2011): 489. http://dx.doi.org/10.1071/ch10421.

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Phytochemical investigation of the stem bark of F. racemosa JACK ex WALL (Loganiaceae) from East Java, Indonesia, has resulted in the isolation of a new alkaloid fagraeoside along with the iridoid glycoside secologanoside. Fagraeoside may be derived from the condensation of secologanin with L-asparagine, and represents a rare example of a terpene alkaloid in which the amino acid component is non-aromatic. Investigation of three additional species of Fagraea provided known lignans, iridoid or secoiridoid glycosides, and flavanol-6-C-glucosides, thus it is likely that iridoid and secoiridoid glu
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Jørgensen, Lars, Steven J. McKerrall, Christian A. Kuttruff, Felix Ungeheuer, Jakob Felding, and Phil S. Baran. "14-Step Synthesis of (+)-Ingenol from (+)-3-Carene." Science 341, no. 6148 (2013): 878–82. http://dx.doi.org/10.1126/science.1241606.

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Ingenol is a diterpenoid with unique architecture and has derivatives possessing important anticancer activity, including the recently Food and Drug Administration–approved Picato, a first-in-class drug for the treatment of the precancerous skin condition actinic keratosis. Currently, that compound is sourced inefficiently from Euphorbia peplus. Here, we detail an efficient, highly stereocontrolled synthesis of (+)-ingenol proceeding in only 14 steps from inexpensive (+)-3-carene and using a two-phase design. This synthesis will allow for the creation of fully synthetic analogs of bioactive in
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Mazur, Marcelina. "SYNTEZA ORAZ AKTYWNOŚĆ ANTYFIDANTNA LAKTONÓW." Wiadomości Chemiczne 77, no. 5 (2023): 533–54. https://doi.org/10.53584/wiadchem.2023.05.6.

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Antifeedants, or food deterrents, are substances that, by acting on the sense of taste of insects, entirely or partially inhibit their feeding and can be used to reduce the population of harmful species. Antifeedants have the advantage of low toxicity and high selectivity towards selected groups of pests, providing an alternative to the classically used insecticides, which usually have a broad spectrum of action and greater toxicity, even towards vertebrates. Among their numerous activities, lactones can exhibit antifeedant properties. However, the use of natural lactones as antifeedants is li
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Oladimeji, Olawale H., and Kufre E. Eberefiak. "Isolation and antimicrobial analysis of a steroidal terpene from the butanol fraction of Byrophyllum pinnatum (Lam.) Oken." European Chemical Bulletin 6, no. 7 (2017): 292. http://dx.doi.org/10.17628/ecb.2017.6.292-294.

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28

Vezzaro, Alice, Sandra T. Krause, Alberto Nonis, Angelo Ramina, Jörg Degenhardt, and Benedetto Ruperti. "Isolation and characterization of terpene synthases potentially involved in flavor development of ripening olive (Olea europaea) fruits." Journal of Plant Physiology 169, no. 9 (2012): 908–14. http://dx.doi.org/10.1016/j.jplph.2012.01.021.

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29

Nurhayati, Awik Puji Dyah, Rarastoeti Pratiwi, Subagus Wahyuono, and Istriyati . "PROLIFERATION INHIBITORY ACTIVITY OF THE ACTIVE FRACTION MARINE SPONGE Cinachyrella sp. AGAINST CELL LINE T47D." KnE Life Sciences 2, no. 1 (2015): 663. http://dx.doi.org/10.18502/kls.v2i1.243.

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<p>Marine sponges Cinachyrella sp. (Family:Tetillidae) in Kukup beach, Kemadang Village, Tanjungsari District, Gunung Kidul, DIY were producing diversity secondary metabolites such as polyketides, alkaloids, peptide and terpene. The purpose of this study was investigated proliferation inhibitory activity of active fraction Cinachyrella sp. against cell line T47D. Sponges samples were collected manually from rocky substrate at depth 0.5 m. The sponges was minced and extracted with 95% ethanol. The ethanol extract was partitioned sequentially with ethyl acetate. The extract ethyl acetate w
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30

Jones, Christopher G., Christopher I. Keeling, Emilio L. Ghisalberti, Elizabeth L. Barbour, Julie A. Plummer, and Jörg Bohlmann. "Isolation of cDNAs and functional characterisation of two multi-product terpene synthase enzymes from sandalwood, Santalum album L." Archives of Biochemistry and Biophysics 477, no. 1 (2008): 121–30. http://dx.doi.org/10.1016/j.abb.2008.05.008.

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31

Guidoti, Daniela Granella Gomes, David Teixeira Guidoti, Adriano Lopes Romero, et al. "Kaurenoic acid from Annona squamosa L. exhibits antiproliferative effect on human tumor cell lines and induces apoptosis in Aspergillus nidulans." Revista Fitos 13, no. 2 (2019): 122–36. http://dx.doi.org/10.17648/2446-4775.2019.716.

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Annona squamosa is a source of bioactive compounds, with several pharmacological activities. However, tests are needed to confirm the safety of these compounds in terms of cytogenotoxic potential and their possible medicinal activity. Thus, the aims of the present study were to isolate kaurenoic acid from sugar apple peel and determine its antiproliferative activity in nine human tumor cell lines and mutagenic activity in germinating Aspergillus nidulans conidia. Chemical extraction resulted in the isolation of kaurenoic acid, a terpene that demonstrated a cytostatic effect at concentrations o
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El Midaoui, Adil, Farid Khallouki, Réjean Couture, et al. "Thymus atlanticus: A Source of Nutrients with Numerous Health Benefits and Important Therapeutic Potential for Age-Related Diseases." Nutrients 15, no. 18 (2023): 4077. http://dx.doi.org/10.3390/nu15184077.

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Thymus atlanticus (Lamiaceae) is a plant endemic to the Mediterranean basin that is found in significant quantities in the arid regions of Morocco. Thymus atlanticus is used in traditional medicine to treat infectious and non-infectious diseases. It is also used for the isolation of essential oils and for the seasoning of many dishes in the Mediterranean diet. The major constituents of Thymus atlanticus are saponins, flavonoids, tannins, alkaloids, various simple and hydroxycinnamic phenolic compounds, and terpene compounds. Several of these compounds act on signaling pathways of oxidative str
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Mierza, Vriezka, Antolin Antolin, Audi Ichsani, Nurma Dwi, Sridevi Sridevi, and Syfa Dwi. "Research Article: Isolasi dan Identifikasi Senyawa Terpenoid." Jurnal Surya Medika 9, no. 2 (2023): 134–41. http://dx.doi.org/10.33084/jsm.v9i2.5681.

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Terpenoids are a group of hydrocarbons that are produced in large quantities by plants and are mainly contained in the sap and cell vacuoles. In plants, terpene compounds and their modifications, terpenoids, are secondary metabolites. Terpenoids make up many of the essential oils produced by plants. The content of essential oils influences the use of spice products, both as seasonings, as fragrances, as well as ingredients for medicine, health, etc. The terpenoid-steroid test was carried out using the Lieberman-Buchard reagent which yielded positive results for terpenoids for all fractions. Th
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Schroeder, Daniel R., and Frank R. Stermitz. "Isolation and synthesis of bishordeninyl terpene alkaloids. Some experiments relating to the natural occurrence of formal Diels-Alder adducts." Tetrahedron 41, no. 19 (1985): 4309–20. http://dx.doi.org/10.1016/s0040-4020(01)97202-3.

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Оленников (Olennikov), Даниил (Daniil) Николаевич (Nikolaevich), and Нина (Nina) Игоревна (Igorevna) Кащенко (Kashchenko). "PHYTOECDYSTEROIDS OF SERRATULA L. AND KLASEA CASS. GENERA: CHEMODIVERSITY, METHODS OF ISOLATION AND ANALYSIS." chemistry of plant raw material, no. 4 (September 14, 2017): 123–35. http://dx.doi.org/10.14258/jcprm.2017042016.

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Serratula L. and Klasea Cass. are two systematically related genera of Asteraceae family containing phytoecdysteroids, a group of natural terpene compounds with various biological activity. Beginning from the 1970s, 76 phytoecdysteroids were isolated and identified in 13 species of Serratula and 5 species of Klasea. This review presented information on the chemodiversity of phytoecdysteroids of Serratula and Klasea genera and their occurrence in individual species. It was shown that the structural features of Serratula and Klasea phytoecdysteroids include the presence of a complete side chain
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36

Lee, Sae-Byuk, and Heui-Dong Park. "Isolation and Investigation of Potential Non-Saccharomyces Yeasts to Improve the Volatile Terpene Compounds in Korean Muscat Bailey A Wine." Microorganisms 8, no. 10 (2020): 1552. http://dx.doi.org/10.3390/microorganisms8101552.

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The Muscat Bailey A (MBA) grape, one of the most prominent grape cultivars in Korea, contains considerable amounts of monoterpene alcohols that have very low odor thresholds and significantly affect the perception of wine aroma. To develop a potential wine starter for Korean MBA wine, nine types of non-Saccharomyces yeasts were isolated from various Korean food materials, including nuruk, Sémillon grapes, persimmons, and Muscat Bailey A grapes, and their physiological, biochemical, and enzymatic properties were investigated and compared to the conventional wine fermentation strain, Saccharomyc
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Weyerstahl, Peter, Christian Christiansen, and Helga Marschall. "Terpenes and Terpene Derivatives, XXX. Isolation and Synthesis of Isohumbertiol, the First Naturally Occurring Sesquiterpene Alcohol with a Humbertiane Skeleton." Liebigs Annalen der Chemie 1992, no. 12 (1992): 1325–28. http://dx.doi.org/10.1002/jlac.1992199201218.

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38

Chang, Yung-Jin, Seung-Hwan Song, Si-Hyung Park, and Soo-Un Kim. "Amorpha-4,11-diene Synthase of Artemisia annua: cDNA Isolation and Bacterial Expression of a Terpene Synthase Involved in Artemisinin Biosynthesis." Archives of Biochemistry and Biophysics 383, no. 2 (2000): 178–84. http://dx.doi.org/10.1006/abbi.2000.2061.

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39

KABORE, Ibrahim, Mamounata DIAO, Samson GUENNE, et al. "Phytochemistry and Alternative use of Sweeteners in Metabolic Diseases." Annals of the Academy of Romanian Scientists Series on Biological Sciences 11, no. 1 (2022): 109–19. http://dx.doi.org/10.56082/annalsarscibio.2022.1.109.

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The plants native to tropical climates and even southern Africa (5/8) are considerable, which served as a matrix for the isolation and identification of natural sweeteners. These compounds of plant origin have become essential in many fields. From the agronomic industry to the pharmaceutical industry, their use is aimed at combating the supply of glucose and additional calories to consumers who wage a fierce fight against metabolic diseases. In this context, that vascular plants capable of harboring new molecules with similar sweet principles are of interest to researchers. Indeed, these molec
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Maksimovic, Svetolik, Vanja Tadic, Jasna Ivanovic, et al. "Utilization of the integrated process of supercritical extraction and impregnation for incorporation of Helichrysum italicum extract into corn starch xerogel." Chemical Industry and Chemical Engineering Quarterly 24, no. 2 (2018): 191–200. http://dx.doi.org/10.2298/ciceq170223031m.

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Supercritical CO2 extraction of Helichrysum italicum and impregnation of starch xerogels with the extract by using an integrated scCO2 extraction and impregnation process were performed at 350 bar and 40?C in order to produce biomaterials for possible oral intake of the extract. Xerogels produced by air-drying of acetogels and alcogels were used as carriers in the supercritical impregnation process. The effect of ethanol as a co-solvent, contact time, plant material/carrier mass ratio and xerogel preparation on the impregnation loading was studied. The highest impregnation loading (1.26?0.22%)
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Zou, Ran, Xin Li, Xiaochen Chen, Yue-Wei Guo, and Baofu Xu. "Chemical and biosynthetic potential of Penicillium shentong XL-F41." Beilstein Journal of Organic Chemistry 20 (March 15, 2024): 597–606. http://dx.doi.org/10.3762/bjoc.20.52.

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Penicillium strains are renowned for producing diverse secondary metabolites with unique structures and promising bioactivities. Our chemical investigations, accompanied by fermentation media optimization, of a newly isolated fungus, Penicillium shentong XL-F41, led to the isolation of twelve compounds. Among these are two novel indole terpene alkaloids, shentonins A and B (1 and 2), and a new fatty acid 3. Shentonin A (1) is distinguished by an unusual methyl modification at the oxygen atom of the typical succinimide ring, a feature not seen in the structurally similar brocaeloid D. Additiona
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Smit, Samuel J., Melané A. Vivier, and Philip R. Young. "Seeing the Forest through the (Phylogenetic) Trees: Functional Characterisation of Grapevine Terpene Synthase (VviTPS) Paralogues and Orthologues." Plants 10, no. 8 (2021): 1520. http://dx.doi.org/10.3390/plants10081520.

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Gene families involved in specialised metabolism play a key role in a myriad of ecophysiological and biochemical functions. The Vitis vinifera sesquiterpene synthases represent the largest subfamily of grapevine terpene synthase (VviTPS) genes and are important volatile metabolites for wine flavour and aroma, as well as ecophysiological interactions. The functional characterisation of VviTPS genes is complicated by a reliance on a single reference genome that greatly underrepresents this large gene family, exacerbated by extensive duplications and paralogy. The recent release of multiple phase
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Alicandri, Enrica, Stefano Covino, Bartolomeo Sebastiani, et al. "Diterpene Resin Acids and Olefins in Calabrian Pine (Pinus nigra subsp. laricio (Poiret) Maire) Oleoresin: GC-MS Profiling of Major Diterpenoids in Different Plant Organs, Molecular Identification and Expression Analysis of Diterpene Synthase Genes." Plants 10, no. 11 (2021): 2391. http://dx.doi.org/10.3390/plants10112391.

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A quali-quantitative analysis of diterpenoid composition in tissues obtained from different organs of Pinus nigra subsp. laricio (Poiret) Maire (Calabrian pine) was carried out. Diterpene resin acids were the most abundant diterpenoids across all the examined tissues. The same nine diterpene resin acids were always found, with the abietane type prevailing on the pimarane type, although their quantitative distribution was found to be remarkably tissue-specific. The scrutiny of the available literature revealed species specificity as well. A phylogeny-based approach allowed us to isolate four cD
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WEYERSTAHL, P., C. CHRISTIANSEN, and H. MARSCHALL. "ChemInform Abstract: Terpenes and Terpene Derivatives. Part 30. Isolation and Synthesis of Isohumbertiol, the First Naturally Occurring Sesquiterpene Alcohol with a Humbertiane Skeleton." ChemInform 24, no. 15 (2010): no. http://dx.doi.org/10.1002/chin.199315239.

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Klimek, Katarzyna, Katarzyna Tyśkiewicz, Malgorzata Miazga-Karska, Agnieszka Dębczak, Edward Rój, and Grazyna Ginalska. "Bioactive Compounds Obtained from Polish “Marynka” Hop Variety Using Efficient Two-Step Supercritical Fluid Extraction and Comparison of Their Antibacterial, Cytotoxic, and Anti-Proliferative Activities In Vitro." Molecules 26, no. 8 (2021): 2366. http://dx.doi.org/10.3390/molecules26082366.

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Given the health-beneficial properties of compounds from hop, there is still a growing trend towards developing successful extraction methods with the highest yield and also receiving the products with high added value. The aim of this study was to develop efficient extraction method for isolation of bioactive compounds from the Polish “Marynka” hop variety. The modified two-step supercritical fluid extraction allowed to obtain two hop samples, namely crude extract (E1), composed of α-acids, β-acids, and terpene derivatives, as well as pure xanthohumol with higher yield than that of other avai
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Umaña, Eduardo, Godofredo Solano, Gabriel Zamora, and Giselle Tamayo-Castillo. "Costa Rican Propolis Chemical Compositions: Nemorosone Found to Be Present in an Exclusive Geographical Zone." Molecules 28, no. 20 (2023): 7081. http://dx.doi.org/10.3390/molecules28207081.

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Background: The chemistry of Costa Rican propolis from Apis mellifera remains underexplored despite its potential applications. This study identified its chemical composition, linking chemotypes to antioxidant potential. Methods: Proton nuclear magnetic resonance (1H NMR) spectra were obtained for 119 propolis extracts and analyzed using multivariate analyses. In parallel, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay was used to assess antioxidant activity. A generalized linear regression model (GLM) correlated this with its chemical profiles and geographical origin. Chromatog
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Tran, Thi Diem Huong, Ngoc Tuyet Nguyen, and Thi Hong Thuong Nguyen. "Isolation and in silico analysis of a transcript variant for a putative terpene synthase (HbTPS6L-X1) from the bark tissues of rubber Hevea brasiliensis RRIV 209." Ministry of Science and Technology, Vietnam 65, no. 12 (2023): 70–76. http://dx.doi.org/10.31276/vjst.65(12).70-76.

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Hevea brasiliensis is the only tree species grown to produce natural rubber. The method of harvesting latex by slicing a groove into the bark of the tree mimics a mechanical wounding. In addition, rubber trees could be frequently exposed to pest and pathogen attacks through the scraped bark region. Terpenoids are a group of specialised compounds that play an important role in plant-environment interactions, especially in plant response to stress factors. The diversity of terpenoids is mainly determined by enzymes of the terpene synthase (TPS) family. Screening the RNA-seq data of H. brasiliens
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Hsu, Chih-Yao, Pung-Ling Huang, Chih-Ming Chen, Chi-Tang Mao, and Shu-Miaw Chaw. "Tangy Scent in Toona sinensis (Meliaceae) Leaflets: Isolation, Functional Characterization, and Regulation of TsTPS1 and TsTPS2, Two Key Terpene Synthase Genes in the Biosynthesis of the Scent Compound." Current Pharmaceutical Biotechnology 13, no. 15 (2012): 2721–32. http://dx.doi.org/10.2174/138920112804724864.

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Sundaraj, Yasotha, Hasdianty Abdullah, Nima Ghahremani Nezhad, Kenneth Francis Rodrigues, Suriana Sabri та Syarul Nataqain Baharum. "Cloning, Expression and Functional Characterization of a Novel α-Humulene Synthase, Responsible for the Formation of Sesquiterpene in Agarwood Originating from Aquilaria malaccensis". Current Issues in Molecular Biology 45, № 11 (2023): 8989–9002. http://dx.doi.org/10.3390/cimb45110564.

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This study describes the cloning, expression and functional characterization of α-humulene synthase, responsible for the formation of the key aromatic compound α-humulene in agarwood originating from Aquilaria malaccensis. The partial sesquiterpene synthase gene from the transcriptome data of A. malaccensis was utilized for full-length gene isolation via a 3′ RACE PCR. The complete gene, denoted as AmDG2, has an open reading frame (ORF) of 1671 bp and encodes for a polypeptide of 556 amino acids. In silico analysis of the protein highlighted several conserved motifs typically found in terpene
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Iyekowa, Osaro, and Mary Olire Edema. "Chemosuppressive activities in in vivo studies of Plasmodium falciparum-infected mice using isolated oil of Stigmaphyllon ovatum (Amazon vine) Cav." Ovidius University Annals of Chemistry 28, no. 1 (2017): 1–6. http://dx.doi.org/10.1515/auoc-2017-0001.

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AbstractProblem: In sub-Saharan Africa, malaria remains one of the leading health problems. This situation has been aggravated by the increasing spread of drug-resistant Plasmodium falciparum strains. The study was conducted to determine the chemosuppressive activities in in vivo studies of Plasmodium falciparum-infected mice with isolated oil of Stigmaphyllon ovatum leaves used in the traditional treatment of malaria in Nigeria. Methodology: The plant leaves were collected, dried, pulverized and extracted in Soxhlet extractor with hexane solvent. The crude extract was concentrated using a rot
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