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Journal articles on the topic 'Terpenes – Metabolism'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

Powell, Jaimie S., and Kenneth F. Raffa. "Fate of Conifer Terpenes in a Polyphagous Folivore: Evidence for Metabolism by Gypsy Moth (Lepidoptera: Lymantriidae)." Journal of Entomological Science 38, no. 4 (2003): 583–601. http://dx.doi.org/10.18474/0749-8004-38.4.583.

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Conifers comprise a substantial portion of the host range of the gypsy moth, Lymantria dispar L. In this study, the effects and fates of the predominant conifer phytochemicals, monoterpenes and diterpene acids, were determined. Gypsy moth larvae were fed physiological levels of three monoterpenes (bornyl acetate, limonene, and myrcene) and two diterpene acids (isopimaric acid and neoabietic acid) for the duration of their second, third, and fourth stadia. Frass was collected daily, and larvae and exuviae were collected after the completion of the stadium. These samples were chemically analyzed

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2

Dickschat, Jeroen S., Ersin Celik, and Nelson L. Brock. "Volatiles from three genome sequenced fungi from the genusAspergillus." Beilstein Journal of Organic Chemistry 14 (April 24, 2018): 900–910. http://dx.doi.org/10.3762/bjoc.14.77.

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The volatiles emitted by agar plate cultures of three genome sequenced fungal strains from the genusAspergilluswere analysed by GC–MS. All three strains produced terpenes for which a biosynthetic relationship is discussed. The obtained data were also correlated to genetic information about the encoded terpene synthases for each strain. Besides terpenes, a series of aromatic compounds and volatiles derived from fatty acid and branched amino acid metabolism were identified. Some of these compounds have not been described as fungal metabolites before. For the compound ethyl (E)-hept-4-enoate know

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3

Hillier, Stephen G., and Richard Lathe. "Terpenes, hormones and life: isoprene rule revisited." Journal of Endocrinology 242, no. 2 (2019): R9—R22. http://dx.doi.org/10.1530/joe-19-0084.

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The year 2019 marks the 80th anniversary of the 1939 Nobel Prize in Chemistry awarded to Leopold Ruzicka (1887–1976) for work on higher terpene molecular structures, including the first chemical synthesis of male sex hormones. Arguably his crowning achievement was the ‘biogenetic isoprene rule’, which helped to unravel the complexities of terpenoid biosynthesis. The rule declares terpenoids to be enzymatically cyclized products of substrate alkene chains containing a characteristic number of linear, head-to-tail condensed, C5 isoprene units. The number of repeat isoprene units dictates the typ

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4

Krill, Christian, Simone Rochfort, and German Spangenberg. "A High-Throughput Method for the Comprehensive Analysis of Terpenes and Terpenoids in Medicinal Cannabis Biomass." Metabolites 10, no. 7 (2020): 276. http://dx.doi.org/10.3390/metabo10070276.

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Cannabis and its secondary metabolite content have recently seen a surge in research interest. Cannabis terpenes and terpenoids in particular are increasingly the focus of research efforts due to the possibility of their contribution to the overall therapeutic effect of medicinal cannabis. Current methodology to quantify terpenes in cannabis biomass mostly relies on large quantities of biomass, long extraction protocols, and long GC gradient times, often exceeding 60 min. They are therefore not easily applicable in the high-throughput environment of a cannabis breeding program. The method pres

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Poudel, Nirmal, Jens Pfannstiel, Oliver Simon, Nadine Walter, Anastassios C. Papageorgiou, and Dieter Jendrossek. "The Pseudomonas aeruginosa Isohexenyl Glutaconyl Coenzyme A Hydratase (AtuE) Is Upregulated in Citronellate-Grown Cells and Belongs to the Crotonase Family." Applied and Environmental Microbiology 81, no. 19 (2015): 6558–66. http://dx.doi.org/10.1128/aem.01686-15.

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ABSTRACTPseudomonas aeruginosais one of only a fewPseudomonasspecies that are able to use acyclic monoterpenoids, such as citronellol and citronellate, as carbon and energy sources. This is achieved by the acyclic terpene utilization pathway (Atu), which includes at least six enzymes (AtuA, AtuB, AtuCF, AtuD, AtuE, AtuG) and is coupled to a functional leucine-isovalerate utilization (Liu) pathway. Here, quantitative proteome analysis was performed to elucidate the terpene metabolism ofP. aeruginosa. The proteomics survey identified 187 proteins, including AtuA to AtuG and LiuA to LiuE, which w

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Boutanaev, Alexander M., Tessa Moses, Jiachen Zi, et al. "Investigation of terpene diversification across multiple sequenced plant genomes." Proceedings of the National Academy of Sciences 112, no. 1 (2014): E81—E88. http://dx.doi.org/10.1073/pnas.1419547112.

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Plants produce an array of specialized metabolites, including chemicals that are important as medicines, flavors, fragrances, pigments and insecticides. The vast majority of this metabolic diversity is untapped. Here we take a systematic approach toward dissecting genetic components of plant specialized metabolism. Focusing on the terpenes, the largest class of plant natural products, we investigate the basis of terpene diversity through analysis of multiple sequenced plant genomes. The primary drivers of terpene diversification are terpenoid synthase (TS) “signature” enzymes (which generate s

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7

Djaafar, Zemali, and Ouahrani M. Ridha. "Phytochemical Study of Selected Medicinal Plant, Solanum Nigrum, the Algerian Desert." International Letters of Chemistry, Physics and Astronomy 20 (October 2013): 25–30. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.20.25.

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Solanum Nigrum plant contains many compounds of High utility, such as: alkaloids, saponin, and others. Through this study in the field of plant chemistry that we can know all the components of the various parts (leaves, twigs, flowers, fruits and roots) of the plant Solanum Nigrum, and enhance the classification of the operations during the disclosure of the components of the plant and contents of secondary metabolism and some of which adopted the newly particularly alkaloids and terpenes as genetic indicators.

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8

Balestrini, Raffaella, Cecilia Brunetti, Maria Cammareri, et al. "Strategies to Modulate Specialized Metabolism in Mediterranean Crops: From Molecular Aspects to Field." International Journal of Molecular Sciences 22, no. 6 (2021): 2887. http://dx.doi.org/10.3390/ijms22062887.

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Plant specialized metabolites (SMs) play an important role in the interaction with the environment and are part of the plant defense response. These natural products are volatile, semi-volatile and non-volatile compounds produced from common building blocks deriving from primary metabolic pathways and rapidly evolved to allow a better adaptation of plants to environmental cues. Specialized metabolites include terpenes, flavonoids, alkaloids, glucosinolates, tannins, resins, etc. that can be used as phytochemicals, food additives, flavoring agents and pharmaceutical compounds. This review will

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9

Germoush, Mousa O., Hassan A. Elgebaly, Sherif Hassan, Emadeldin M. Kamel, May Bin-Jumah та Ayman M. Mahmoud. "Consumption of Terpenoids-Rich Padina pavonia Extract Attenuates Hyperglycemia, Insulin Resistance and Oxidative Stress, and Upregulates PPARγ in a Rat Model of Type 2 Diabetes". Antioxidants 9, № 1 (2019): 22. http://dx.doi.org/10.3390/antiox9010022.

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Seaweeds are rich in structurally diverse bioactive compounds with promising therapeutic effects. This study aimed to isolate and identify terpenes from the brown alga Padina pavonia and to investigate its antidiabetic activity, pointing to the possible involvement of peroxisome proliferator-activated receptor (PPAR)γ. Type 2 diabetes was induced by feeding rats a high fat diet (HFD) for 4 weeks followed by injection of 35 mg/kg streptozotocin (STZ). The diabetic rats received P. pavonia extract (PPE; 50, 100 and 200 mg/kg) for 4 weeks and samples were collected for analyses. HFD/STZ-induced r

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10

Sardans, Jordi, Albert Gargallo-Garriga, Otmar Urban, et al. "Ecometabolomics for a Better Understanding of Plant Responses and Acclimation to Abiotic Factors Linked to Global Change." Metabolites 10, no. 6 (2020): 239. http://dx.doi.org/10.3390/metabo10060239.

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The number of ecometabolomic studies, which use metabolomic analyses to disentangle organisms’ metabolic responses and acclimation to a changing environment, has grown exponentially in recent years. Here, we review the results and conclusions of ecometabolomic studies on the impacts of four main drivers of global change (increasing frequencies of drought episodes, heat stress, increasing atmospheric carbon dioxide (CO2) concentrations and increasing nitrogen (N) loads) on plant metabolism. Ecometabolomic studies of drought effects confirmed findings of previous target studies, in which most ch

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Silva, Evandro, José Perez da Graça, Carla Porto, et al. "Untargeted Metabolomics Analysis by UHPLC-MS/MS of Soybean Plant in a Compatible Response to Phakopsora pachyrhizi Infection." Metabolites 11, no. 3 (2021): 179. http://dx.doi.org/10.3390/metabo11030179.

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Phakopsora pachyrhizi is a biotrophic fungus, causer of the disease Asian Soybean Rust, a severe crop disease of soybean and one that demands greater investment from producers. Thus, research efforts to control this disease are still needed. We investigated the expression of metabolites in soybean plants presenting a resistant genotype inoculated with P. pachyrhizi through the untargeted metabolomics approach. The analysis was performed in control and inoculated plants with P. pachyrhizi using UHPLC-MS/MS. Principal component analysis (PCA) and the partial least squares discriminant analysis (

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12

Hubich, Aksana I., Yanina A. Bandyk, Natalya A. Zalesskaya, Svyatlana S. Okarakava, Alena I. Kapanic, and Alina E. Herasimava. "The investigation of adaptogenic, hypoglycemic and hepatoprotective properties of Clitoria ternatea L. on experimental models in vivo." Journal of the Belarusian State University. Biology, no. 1 (February 24, 2020): 27–38. http://dx.doi.org/10.33581/2521-1722-2020-1-27-38.

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This work is devoted to the study of the effect of Clitoria ternatea L. decoction for energy and carbohydrate metabolism in conditions of increased physical activity, the analysis of possibilities carbohydrate and lipid metabolism markers correcting in a model of experimental hyperphagia and experimental diabetes, and the efficiency of the stabilization of liver injury and lipid peroxidation markers in rats in an experimental model of chronic alcohol intoxication. It’s established that Clitoria ternatea L. has a stabilizing effect on carbohydrate metabolism in rats with experimental diabetes a

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13

Shoker, Roaa M. H. "A Review Article: The Importance of the Major groups of Plants Secondary Metabolism Phenols, Alkaloids, and Terpenes." International Journal For Research in Applied Sciences and Biotechnology 7, no. 5 (2020): 354–58. http://dx.doi.org/10.31033/ijrasb.7.5.47.

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14

Gil, Mariana, Mariela Pontin, Federico Berli, Rubén Bottini, and Patricia Piccoli. "Metabolism of terpenes in the response of grape (Vitis vinifera L.) leaf tissues to UV-B radiation." Phytochemistry 77 (May 2012): 89–98. http://dx.doi.org/10.1016/j.phytochem.2011.12.011.

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15

Yuan, Fang, Ke Cheng, Jihui Gao, and Siyi Pan. "Characterization of Cultivar Differences of Blueberry Wines Using GC-QTOF-MS and Metabolic Profiling Methods." Molecules 23, no. 9 (2018): 2376. http://dx.doi.org/10.3390/molecules23092376.

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A non-targeted volatile metabolomic approach based on the gas chromatography-quadrupole time of fight-mass spectrometry (GC-QTOF-MS) coupled with two different sample extraction techniques (solid phase extraction and solid phase microextraction) was developed. Combined mass spectra of blueberry wine samples, which originated from two different cultivars, were subjected to orthogonal partial least squares-discriminant analysis (OPLS-DA). Principal component analysis (PCA) reveals an excellent separation and OPLS-DA highlight metabolic features responsible for the separation. Metabolic features

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16

Ahanger, Mohammad Abass, Javaid Akhter Bhat, Manzer H. Siddiqui, Jörg Rinklebe, and Parvaiz Ahmad. "Integration of silicon and secondary metabolites in plants: a significant association in stress tolerance." Journal of Experimental Botany 71, no. 21 (2020): 6758–74. http://dx.doi.org/10.1093/jxb/eraa291.

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Abstract As sessile organisms, plants are unable to avoid being subjected to environmental stresses that negatively affect their growth and productivity. Instead, they utilize various mechanisms at the morphological, physiological, and biochemical levels to alleviate the deleterious effects of such stresses. Amongst these, secondary metabolites produced by plants represent an important component of the defense system. Secondary metabolites, namely phenolics, terpenes, and nitrogen-containing compounds, have been extensively demonstrated to protect plants against multiple stresses, both biotic

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17

Pedišius, Vilmantas. "UV-B absorbing and bioactive secondary compounds in lichens Xanthoria elegans and Xanthoria parietina: A review." Czech Polar Reports 10, no. 2 (2020): 252–62. http://dx.doi.org/10.5817/cpr2020-2-19.

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Secondary metabolites are the bioactive compounds of plants which are synthesized during primary metabolism, have no role in the development process but are needed for defense and other special purposes. These secondary metabolites, such as flavonoids, terpenes, alkaloids, anthraquinones and carotenoids, are found in Xanthoria genus lichens. These lichens are known as lichenized fungi in the family Teloschistaceae, which grows on rock and produce bioactive compounds. A lot of secondary compounds in plants are induced by UV (100-400 nm) spectra. The present review showcases the present identifi

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18

Auti, Sandip T., and Yogesh A. Kulkarni. "A Systematic Review on the Role of Natural Products in Modulating the Pathways in Alzheimer’s Disease." International Journal for Vitamin and Nutrition Research 87, no. 1-2 (2017): 99–116. http://dx.doi.org/10.1024/0300-9831/a000405.

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Abstract. Alzheimer’s disease (AD) is the most common neurodegenerative disorder to date, with no cure or preventive therapy. Histopathological hallmarks of AD include deposition of β-amyloid plaques and formation of neurofibrillary tangles in brain. Despite extensive research, only five approved drugs are available for the management of AD. Hence, there is a need to look for alternative therapies and new drugs. Use of natural products in medicine has gained popularity in recent years and several natural compounds with neuroprotective effects have been studied in detail. Some of them target th

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19

Nicault, Matthieu, Abdoul-Razak Tidjani, Anthony Gauthier, et al. "Mining the Biosynthetic Potential for Specialized Metabolism of a Streptomyces Soil Community." Antibiotics 9, no. 5 (2020): 271. http://dx.doi.org/10.3390/antibiotics9050271.

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The diversity and distribution of specialized metabolite gene clusters within a community of bacteria living in the same soil habitat are poorly documented. Here we analyzed the genomes of 8 Streptomyces isolated at micro-scale from a forest soil that belong to the same species or to different species. The results reveal high levels of diversity, with a total of 261 biosynthesis gene clusters (BGCs) encoding metabolites such as terpenes, polyketides (PKs), non-ribosomal peptides (NRPs) and ribosomally synthesized and post-translationally modified peptides (RiPPs) with potential bioactivities.

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20

Rzajew, Jowita, Tomasz Radzik, and Elzbieta Rebas. "Calcium-Involved Action of Phytochemicals: Carotenoids and Monoterpenes in the Brain." International Journal of Molecular Sciences 21, no. 4 (2020): 1428. http://dx.doi.org/10.3390/ijms21041428.

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Background: Neurodegenerative and mood disorders represent growing medical and social problems, many of which are provoked by oxidative stress, disruption in the metabolism of various neurotransmitters, and disturbances in calcium homeostasis. Biologically active plant compounds have been shown to exert a positive impact on the function of calcium in the central nervous system. Methods: The present paper reviews studies of naturally occurring terpenes and derivatives and the calcium-based aspects of their mechanisms of action, as these are known to act upon a number of targets linked to neurol

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21

Pass, G. J., and S. McLean. "Inhibition of the microsomal metabolism of 1,8-cineole in the common brushtail possum (Trichosurus vulpecula) by terpenes and other chemicals." Xenobiotica 32, no. 12 (2002): 1109–26. http://dx.doi.org/10.1080/0049825021000022294.

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22

Cao, Yang, Wei Ding, and Chang Liu. "Unraveling the Metabolite Signature of Endophytic Bacillus velezensis Strain Showing Defense Response towards Fusarium oxysporum." Agronomy 11, no. 4 (2021): 683. http://dx.doi.org/10.3390/agronomy11040683.

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Seedling blight, caused by the fungus Fusarium oxysporum, significantly lowers rice production globally. Earlier reports have opined that endophytic bacteria strains could be possible biocontrol agents, but the mechanistic actions involved are still unclear. Therefore, this study aimed to isolate the endophytic bacteria with high inhibitory activity and elucidate its possible mechanisms for inducing resistance by metabolomics. The results showed that mdj-36 had the strongest in vitro pathogen inhibition of F. oxysporum, while mdj-34 displayed the lowest inhibitory activity identified as Bacill

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23

YANI, A., G. PAULY, M. FAYE, F. SALIN, and M. GLEIZES. "The effect of a long-term water stress on the metabolism and emission of terpenes of the foliage of Cupressus sempervirens." Plant, Cell and Environment 16, no. 8 (1993): 975–81. http://dx.doi.org/10.1111/j.1365-3040.1993.tb00521.x.

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24

S, Mukunthan K., Balaji B, and Patrl Tn. "BLACK TURMERIC DATABASE: A DATABASE OF NATURAL COMPOUNDS FROM CURCUMA CAESIA ROXB." Asian Journal of Pharmaceutical and Clinical Research 11, no. 3 (2018): 406. http://dx.doi.org/10.22159/ajpcr.2018.v11i3.24204.

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Objective: Most species have their trademark metabolites or a class of chemicals that are generally disseminated inside the genus variety. Secondary metabolites from the black turmeric are predominantly camphor, terpenes, lactones, alkaloids, and phenols classification. A database was constructed with the predicted absorption, distribution, metabolism, elimination, and toxicity, druglikeliness, and physiochemical properties of the exclusive black turmeric 103 compounds. Methods: The interface has been designed using Microsoft Structured Query Language platform, keeping in mind the ease of use

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25

Swamy, Mallappa Kumara, Mohd Sayeed Akhtar, and Uma Rani Sinniah. "Antimicrobial Properties of Plant Essential Oils against Human Pathogens and Their Mode of Action: An Updated Review." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–21. http://dx.doi.org/10.1155/2016/3012462.

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A wide range of medicinal and aromatic plants (MAPs) have been explored for their essential oils in the past few decades. Essential oils are complex volatile compounds, synthesized naturally in different plant parts during the process of secondary metabolism. Essential oils have great potential in the field of biomedicine as they effectively destroy several bacterial, fungal, and viral pathogens. The presence of different types of aldehydes, phenolics, terpenes, and other antimicrobial compounds means that the essential oils are effective against a diverse range of pathogens. The reactivity of

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Ahmad, Javed, Rita Bagheri, Humayra Bashir, et al. "Organ-Specific Phytochemical Profiling and Antioxidant Analysis of Parthenium hysterophorus L." BioMed Research International 2018 (June 20, 2018): 1–10. http://dx.doi.org/10.1155/2018/9535232.

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Parthenium hysterophorus is a weed of global concern with high threshold of tolerance against most of biotic and abiotic stresses. Phytochemical profile and in vitro antioxidant analysis may help in understanding its tolerance to stresses. Root, stem, leaf, phyllary, and receptacle (including disc and ray florets) were chemotyped employing GC tof-MS and assessed for antioxidant activity by DPPH, FRAP, HRSA, and TAC assays. Phytochemicals identified were terpenes, fatty acids, hydrocarbons, phytosterols, and compounds of miscellaneous chemical nature. Organ-specific maximum concentration of met

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Ziko, Laila, Mustafa Adel, Mohamed N. Malash, and Rania Siam. "Insights into Red Sea Brine Pool Specialized Metabolism Gene Clusters Encoding Potential Metabolites for Biotechnological Applications and Extremophile Survival." Marine Drugs 17, no. 5 (2019): 273. http://dx.doi.org/10.3390/md17050273.

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The recent rise in antibiotic and chemotherapeutic resistance necessitates the search for novel drugs. Potential therapeutics can be produced by specialized metabolism gene clusters (SMGCs). We mined for SMGCs in metagenomic samples from Atlantis II Deep, Discovery Deep and Kebrit Deep Red Sea brine pools. Shotgun sequence assembly and secondary metabolite analysis shell (antiSMASH) screening unraveled 2751 Red Sea brine SMGCs, pertaining to 28 classes. Predicted categorization of the SMGC products included those (1) commonly abundant in microbes (saccharides, fatty acids, aryl polyenes, acyl-

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Hanifah, Abu, Awang Maharijaya, Sastia P. Putri, Walter A. Laviña, and Sobir. "Untargeted Metabolomics Analysis of Eggplant (Solanum melongena L.) Fruit and Its Correlation to Fruit Morphologies." Metabolites 8, no. 3 (2018): 49. http://dx.doi.org/10.3390/metabo8030049.

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Eggplant is one of the most widely cultivated vegetables in the world and has high biodiversity in terms of fruit shape, size, and color. Therefore, fruit morphology and nutrient content become important considerations for both consumers and breeders who develop new eggplant-based products. To gain insight on the diversity of eggplant metabolites, twenty-one eggplant accessions were analyzed by untargeted metabolomics using GC-MS and LC-MS. The dataset of eggplant fruit morphologies, and metabolites specific to different eggplant fruit accessions were used for correlation analysis. Untargeted

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Cadar, Emin, Aneta Tomescu, Cristina Luiza Erimia, Alef Mustafa, and Rodica Sîrbu. "The Impact of Alkaloids Structures from NaturalCompounds on Public Health." European Journal of Social Sciences Education and Research 5, no. 1 (2015): 34. http://dx.doi.org/10.26417/ejser.v5i1.p34-39.

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Alkaloids are organic heterocycle substances with nitrogen, of plant origin, with basic character, arising from the secondary metabolism of plants, which give characteristic reactions and exert an effect on animal bodies, most often of a toxic nature. Alkaloids have at least one atom of heterocycle nitrogen, in which case it is often tertiary, less frequently quaternary. The heterocycles can condense among themselves or with other cycles in such a way that alkaloid molecules may become poly- or macro-cycles. Alkaloids are classified on both the criterion of chemical structure, as well as based

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Islam, Md Asiful, Fahmida Alam, Md Solayman, Md Ibrahim Khalil, Mohammad Amjad Kamal, and Siew Hua Gan. "Dietary Phytochemicals: Natural Swords Combating Inflammation and Oxidation-Mediated Degenerative Diseases." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–25. http://dx.doi.org/10.1155/2016/5137431.

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Cumulatively, degenerative disease is one of the most fatal groups of diseases, and it contributes to the mortality and poor quality of life in the world while increasing the economic burden of the sufferers. Oxidative stress and inflammation are the major pathogenic causes of degenerative diseases such as rheumatoid arthritis (RA), diabetes mellitus (DM), and cardiovascular disease (CVD). Although a number of synthetic medications are used to treat these diseases, none of the current regimens are completely safe. Phytochemicals (polyphenols, carotenoids, anthocyanins, alkaloids, glycosides, s

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Bordunova, Olga, Evgeniya Samokhina, Leontiі Khmelnychyi, Mykola Povod, and Victoria Vechorka. "ZOOHYGIENIC CHARACTERISTICS OF BIOTECHNOLOGICAL METHODS OF METABOLISM REGULATING OF CHICKENS EMBRYO IN THE PROCESS OF INCUBATION." Bulletin of Sumy National Agrarian University. The series: Livestock, no. 4(43) (December 25, 2020): 100–105. http://dx.doi.org/10.32845/bsnau.lvst.2020.4.15.

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The research presents the results of experimental studies of the influence of various physicochemical factors (phonophoresis, electrophoresis, electrospray, diffusion, etc.) on the rate of transport of biologically active substances through the protective layer of hatchig eggs shell of crossbred Haysex Brown. The aim of the study was to compare the effectiveness of the use of physicochemical methods of transportation of biologically active substances through the shell of hatching eggs of chickens. For the experiment, three batches of eggs were formed, which were obtained from layer hens Haysex

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Bordunova, Olga, Evgeniya Samokhina, Leontiy Khmelnychyi, Mykola Povod, and Victoria Vechorka. "ZOOHYGIENIC CHARACTERISTICS OF BIOTECHNOLOGICAL METHODS OF METABOLISM REGULATING OF CHICKENS EMBRYO IN THE PROCESS OF INCUBATION." Bulletin of Sumy National Agrarian University. The series: Livestock, no. 1(44) (March 29, 2021): 36–41. http://dx.doi.org/10.32845/bsnau.lvst.2021.1.5.

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 The research presents the results of experimental studies of the influence of various physicochemical factors (phonophoresis, electrophoresis, electrospray, diffusion, etc.) on the rate of transport of biologically active substances through the protective layer of hatching eggs shell of crossbred Haysex Brown. The aim of the study was to compare the effectiveness of the use of physicochemical methods of transportation of biologically active substances through the shell of hatching eggs of chickens. For the experiment, three batches of eggs were formed, which were obtained from layer hen

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33

Zhao, Xiting, Lingyu Song, Mengdan Ma, et al. "RNA-Seq for excavation of genes involved in the biosynthesis of primary active components and identification of new EST-SSR markers in medicinal chrysanthemum." Archives of Biological Sciences 71, no. 3 (2019): 489–500. http://dx.doi.org/10.2298/abs181226032z.

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Chrysanthemum morifolium cv. ?Huaihuang? has great medicinal and commercial value. However, limited genomic and transcriptional information restricts the further research of ?Huaihuang?. In this study, using ?Huaihuang? leaf as the sample, we performed RNA-Seq and obtained numerous unigene sequences for functional characterization, and developed new EST-SSR markers. The results show that 176 unigenes were assigned to the ?antioxidant activity? in GO annotations, 998 unigenes were assigned to ?Secondary metabolite biosynthesis, transport and catabolism? in the KOG database, 381 unigenes were as

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Jaramillo-Colorado, Beatriz Eugenia, Flor María Palacio-Herrera, and Cruz Nayive Pino-Benítez. "Volatile chemical composition of Colombian Piper gorgonillense Trel. & Yunck. essential oil and its repellent and fumigant activity against Tribolium castaneum Herbst." Revista Colombiana de Ciencias Hortícolas 14, no. 3 (2020): 424–33. http://dx.doi.org/10.17584/rcch.2020v14i3.11061.

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Essential oils (EOs) are mixtures of volatile organic compounds, mostly terpenes, from the secondary metabolism of plants. These oils exert various activities on insects that damage crops and cause losses worldwide for the economy and agriculture. Tribolium castaneum Herbst (Coleoptera: Tenebrionidae) is one of the main pests causing the loss of a large amount of stored food. The objective of this study was to evaluate the volatile chemical composition of the essential oil from Piper gorgonillense Trel. & Yunck. and its repellent and fumigant activity on T. castaneum. The volatile composit

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Shehadeh, Mayadah Bashir, Ghadeer A. R. Y. Suaifan, and Ala’ Mustafa Abu-Odeh. "Plants Secondary Metabolites as Blood Glucose-Lowering Molecules." Molecules 26, no. 14 (2021): 4333. http://dx.doi.org/10.3390/molecules26144333.

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Recently, significant advances in modern medicine and therapeutic agents have been achieved. However, the search for effective antidiabetic drugs is continuous and challenging. Over the past decades, there has been an increasing body of literature related to the effects of secondary metabolites from botanical sources on diabetes. Plants-derived metabolites including alkaloids, phenols, anthocyanins, flavonoids, stilbenoids, saponins, tannins, polysaccharides, coumarins, and terpenes can target cellular and molecular mechanisms involved in carbohydrate metabolism. In addition, they can grant pr

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Neto, Luiz Jardelino de Lacerda, Andreza Guedes Barbosa Ramos, Thiago Sampaio de Freitas, et al. "Evaluation of Benzaldehyde as an Antibiotic Modulator and Its Toxic Effect against Drosophila melanogaster." Molecules 26, no. 18 (2021): 5570. http://dx.doi.org/10.3390/molecules26185570.

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Products of natural origin remain important in the discovery of new bioactive molecules and are less damaging to the environment. Benzaldehyde is a product of the metabolism of plants, and similarly to oxygenated terpenes, it can have antibacterial activity against Staphylococcus aureus and toxic action against Drosophila melanogaster; we aimed to verify these activities. The broth microdilution tests determined the minimum inhibitory concentration (MIC) of benzaldehyde alone and in association with antibiotics and ethidium bromide (EtBr). Toxicity against Drosophila melanogaster was determine

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Ben Saad, Amina, Mohamed Tiss, Henda Keskes, et al. "Antihyperlipidemic, Antihyperglycemic, and Liver Function Protection of Olea europaea var. Meski Stone and Seed Extracts: LC-ESI-HRMS-Based Composition Analysis." Journal of Diabetes Research 2021 (March 17, 2021): 1–10. http://dx.doi.org/10.1155/2021/6659415.

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Methanol and methanol/water extracts of olive stones and seeds from Olea europaea var. meski were analyzed by reversed-phase high-performance liquid chromatography (HPLC) with diode array detection and mass spectrometry (LC-MS/MS). A total of 28 metabolites were identified; among them are hydroxycinnamic acid derivatives, phenolic alcohols, flavonoids and flavonoid glucosides, secoiridoids, and terpenes. All the extracts were screened for the inhibitory effect of key enzymes related to diabetes and obesity, such as α-amylase and lipase. An in vitro study revealed that Olea meski stone ethanol

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Liu, Yu, Hui Zhang, Shivshankar Umashankar, et al. "Characterization of Plant Volatiles Reveals Distinct Metabolic Profiles and Pathways among 12 Brassicaceae Vegetables." Metabolites 8, no. 4 (2018): 94. http://dx.doi.org/10.3390/metabo8040094.

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Plants emit characteristic organic volatile compounds (VOCs) with diverse biological/ecological functions. However, the links between plant species/varieties and their phytochemical emission profiles remain elusive. Here, we developed a direct headspace solid-phase microextraction (HS-SPME) technique and combined with non-targeted gas chromatography‒high-resolution mass spectrometry (GC-HRMS) platform to investigate the VOCs profiles of 12 common Brassicaceae vegetables (watercress, rocket, Brussels sprouts, broccoli, kai lan, choy sum, pak choi, cabbage, Chinese cabbage, cauliflower, radish a

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Deryabin, Dmitry, Anna Galadzhieva, Dianna Kosyan, and Galimjan Duskaev. "Plant-Derived Inhibitors of AHL-Mediated Quorum Sensing in Bacteria: Modes of Action." International Journal of Molecular Sciences 20, no. 22 (2019): 5588. http://dx.doi.org/10.3390/ijms20225588.

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Numerous gram-negative phytopathogenic and zoopathogenic bacteria utilise acylated homoserine lactone (AHL) in communication systems, referred to as quorum sensing (QS), for induction of virulence factors and biofilm development. This phenomenon positions AHL-mediated QS as an attractive target for anti-infective therapy. This review focused on the most significant groups of plant-derived QS inhibitors and well-studied individual compounds for which in silico, in vitro and in vivo studies provide substantial knowledge about their modes of anti-QS activity. The current data about sulfur-contain

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Nanou, Alexandra, Athanasios Mallouchos, and Efstathios Z. Panagou. "Elucidation of the Volatilome of Packaged Spanish-Style Green Olives of Conservolea and Halkidiki Varieties Using SPME-GC/MS." Proceedings 70, no. 1 (2020): 75. http://dx.doi.org/10.3390/foods_2020-07629.

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Olives are characterized by a wide variety of volatile compounds, which are primarily products of microbial metabolism that contribute to the organoleptic characteristics of the final product and especially to its flavor. The volatilome in Spanish-style processed green olives of Conservolea and Halkidiki cultivars were analytically characterized. A solid phase micro-extraction (SPME) technique was used for the extraction of volatile components from the olive samples that were further identified and quantified by gas chromatography coupled to mass spectrometry (GC–MS). Eighty-eight (88) compoun

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Landi, Simone, Roberto Berni, Giorgia Capasso, Jean-Francois Hausman, Gea Guerriero, and Sergio Esposito. "Impact of Nitrogen Nutrition on Cannabis sativa: An Update on the Current Knowledge and Future Prospects." International Journal of Molecular Sciences 20, no. 22 (2019): 5803. http://dx.doi.org/10.3390/ijms20225803.

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Nitrogen (N) availability represents one of the most critical factors affecting cultivated crops. N is indeed a crucial macronutrient influencing major aspects, from plant development to productivity and final yield of lignocellulosic biomass, as well as content of bioactive molecules. N metabolism is fundamental as it is at the crossroad between primary and secondary metabolic pathways: Besides affecting the synthesis of fundamental macromolecules, such as nucleic acids and proteins, N is needed for other types of molecules intervening in the response to exogenous stresses, e.g. alkaloids and

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Eberhardt, HJ. "The Regulation and Biochemical Action of Natural Fungicides in Tobacco." Beiträge zur Tabakforschung International/Contributions to Tobacco Research 16, no. 4 (1995): 157–70. http://dx.doi.org/10.2478/cttr-2013-0644.

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AbstractThe biochemical interactions between the tobacco plant and a fungal pathogen are complex and poorly understood. Upon infection, the fungus overcomes the natural defence mechanism of the host by the lytic activity of enzymes and by suppressing the hypersensitive reaction of N. tabacum. The ability of the tobacco plant to resist a fungal attack is based on macroscopic properties and the biosynthesis of natural fungicides. The physical and biochemical character of the leaf surface (e.g. trichome exudates, cuticular components) may prevent the fungus from entering the organism. Constitutiv

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Bicker, Joana, Ana Fortuna, Gilberto Alves, and Amílcar Falcão. "Nose-to-brain Delivery of Natural Compounds for the Treatment of Central Nervous System Disorders." Current Pharmaceutical Design 26, no. 5 (2020): 594–619. http://dx.doi.org/10.2174/1381612826666200115101544.

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Background: Several natural compounds have demonstrated potential for the treatment of central nervous system disorders such as ischemic cerebrovascular disease, glioblastoma, neuropathic pain, neurodegenerative diseases, multiple sclerosis and migraine. This is due to their well-known antioxidant, anti-inflammatory, neuroprotective, anti-tumor, anti-ischemic and analgesic properties. Nevertheless, many of these molecules have poor aqueous solubility, low bioavailability and extensive gastrointestinal and/or hepatic first-pass metabolism, leading to a quick elimination as well as low serum and

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King, Drew J., Roslyn M. Gleadow, and Ian E. Woodrow. "The accumulation of terpenoid oils does not incur a growth cost in Eucalyptus polybractea seedlings." Functional Plant Biology 33, no. 5 (2006): 497. http://dx.doi.org/10.1071/fp05304.

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The deployment of secondary metabolites, such as terpenes, as anti-herbivore defences is thought to be costly for plants in terms of primary metabolism. Moreover, it is assumed that the cost of this deployment is modified by resource availability. In this study we examined the impact of terpenoid oil accumulation on the growth of Eucalyptus polybractea R.T.Baker seedlings from four maternal half-sib families, under conditions of sufficient and limiting nitrogen. The foliar oil concentration measured was extremely variable, varying almost 20-fold to a maximum of 13% (w / DW). Oil concentration

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Gómez, Clemencia, Ricardo Arango, Ligia Patricia Arévalo, et al. "Algunos estudios de alelopatía de Rumex crispus L. y Polygonum segetum HBK., en Colombia." Corpoica Ciencia y Tecnología Agropecuaria 4, no. 1 (2003): 42. http://dx.doi.org/10.21930/rcta.vol4_num1_art:12.

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<p>La lengua de vaca (<em>Rumex crispus L.</em>) y la gualola (<em>Polygonum segetum </em>HBK.), son espécies de malezas comunes que crecen en las áreas subtropicales del mundo donde ocasionan grandes pérdidas en cosechas y praderas debido a su agresividad. En Colombia se encuentran en zonas ubicadas por encima de los 2000 msnm, y son muy difíciles de manejar por su alta competitividad y gran habilidad para propagarse, tanto sexual como vegetativamente; a menudo crecen solas en un campo gracias a su capacidad para prevalecer sobre otras especies de plantas. Con el

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Duggan, Peter J. "The Chemistry of Cannabis and Cannabinoids." Australian Journal of Chemistry 74, no. 6 (2021): 369. http://dx.doi.org/10.1071/ch21006.

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The science of cannabis and cannabinoids encompasses a wide variety of scientific disciplines and can appear daunting to newcomers to the field. The encroachment of folklore and ‘cannabis culture’ into scientific discussions can cloud the situation further. This Primer Review is designed to give a succinct overview of the chemistry of cannabis and cannabinoids. It is hoped that it will provide a useful resource for chemistry undergraduates, postgraduates and their instructors, and experienced chemists who require a comprehensive and up to date summary of the field. The Review begins with a bri

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Welling, Matthew T., Myrna A. Deseo, Antony Bacic, and Monika S. Doblin. "Untargeted Metabolomic Analyses Reveal Chemical Complexity of Dioecious Cannabis Flowers." Australian Journal of Chemistry 74, no. 6 (2021): 463. http://dx.doi.org/10.1071/ch21033.

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Cannabis is a mostly dioecious multi-use flowering plant genus. Sexual dimorphism is an important characteristic in Cannabis-based commercial production systems, which has consequences for fibre, seed, and the yield of secondary metabolites, such as phytocannabinoid and terpenes for therapeutic uses. Beyond the obvious morphological differences between male and female plants, metabolic variation among dioecious flowers is largely undefined. Here, we report a pilot metabolomic study comparing staminate (male) and pistillate (female) unisexual flowers. Enrichment of the α-linolenic acid pathway

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Tholl, Dorothea, and Sungbeom Lee. "Terpene Specialized Metabolism inArabidopsis thaliana." Arabidopsis Book 9 (January 2011): e0143. http://dx.doi.org/10.1199/tab.0143.

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Zhou, Si-Si, and Jian-Guo Jiang. "Anti-fatigue Effects of Active Ingredients from Traditional Chinese Medicine: A Review." Current Medicinal Chemistry 26, no. 10 (2019): 1833–48. http://dx.doi.org/10.2174/0929867324666170414164607.

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Background: The application of traditional Chinese medicine (TCM) in the treatment of fatigue has long been practiced in clinical and showed significant effects. Objective: This article summarizes the work done on the natural products from TCM that are reported to have effects of treating fatigue, in the past two decades. Method: Research status, sources, models, efficacy and mechanisms of active ingredients and their monomer in the treatment of fatigue are discussed. Results: Pharmacological research shows that active ingredients of polysaccharide can significantly improve body’s resistance t

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Iqbal, Sajid, John Vollmers, and Hussnain Ahmed Janjua. "Genome Mining and Comparative Genome Analysis Revealed Niche-Specific Genome Expansion in Antibacterial Bacillus pumilus Strain SF-4." Genes 12, no. 7 (2021): 1060. http://dx.doi.org/10.3390/genes12071060.

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The present study reports the isolation of antibacterial exhibiting Bacillus pumilus (B. pumilus) SF-4 from soil field. The genome of this strain SF-4 was sequenced and analyzed to acquire in-depth genomic level insight related to functional diversity, evolutionary history, and biosynthetic potential. The genome of the strain SF-4 harbor 12 Biosynthetic Gene Clusters (BGCs) including four Non-ribosomal peptide synthetases (NRPSs), two terpenes, and one each of Type III polyketide synthases (PKSs), hybrid (NRPS/PKS), lipopeptide, β-lactone, and bacteriocin clusters. Plant growth-promoting genes

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