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Journal articles on the topic 'Test 3F'

Author: Grafiati

Published: 28 June 2021

Last updated: 29 July 2025

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1

Casupanan, Ivy Hipolito, and Lady Grace FabeliÑa Madriaga. "3F-PT technique in improving the spelling and vocabulary skills of grade 2 pupils at Sta. Rita Elementary School." HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE - SOCIAL SCIENCES 15, no. 2 (2024): 24–36. https://doi.org/10.46223/hcmcoujs.soci.en.15.2.3180.2025.

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This study aimed to evaluate the impact of the three Fridays spelling day and a post-test on the last Friday of the month (3F-PT) technique in improving the spelling and vocabulary skills of Grade 2 pupils at Sta. Rita Elementary School. The research focused on 138 Grade 2 pupils during the academic year 2020 - 2021 and investigated the level of spelling and vocabulary skills on the pre-test and post-test of the experimental group taught using the 3F-PT technique and the control group taught using the traditional method. Mean scores, standard deviations, paired t-test and t-test for independen

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Tran, Huu Tam, Oanh Nhu Thi Vu, Thuy Nhu Thi Le, Bao Dam Chau Nguyen, and Ngoc Nguyen Vo. "Substitution to Position Number 2 of 4(3H)-Quinazolinone to Create New Derivatives and to Test the Antibacterial or Antifungal Effects." Applied Sciences 12, no. 5 (2022): 2710. http://dx.doi.org/10.3390/app12052710.

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The campaign “No action today, no cure tomorrow” against antimicrobial resistance proposed by the World Health Organization (WHO) has not only propeled people to take action to prevent antimicrobial resistance, but has also encouraged researchers to develop new antimicrobial agents. 4(3H)-quinazolinone and its derivatives belong to a group of compounds with many potential applications; this study was conducted to find new derivatives of heterocyclic 4(3H)-quinazolinone with biological effects, contributing to research on antibacterial and antifungal compounds. Using the closed-loop method betw

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Akhtar, Muhammad Shoaib, Aziz-Ur Rehman, Haroon Arshad, et al. "In Vitro Antioxidant Activities and the Therapeutic Potential of Some Newly Synthesized Chalcones Against 4-Acetaminophenol Induced Hepatotoxicity in Rats." Dose-Response 19, no. 1 (2021): 155932582199695. http://dx.doi.org/10.1177/1559325821996955.

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The lack of safety and efficacy of existing hepatoprotective agents urge the need to explore novel hepatoprotective agents. The research work was planned to study the therapeutic potential of some newly synthesized chalcones against 4-acetaminophenol induced hepatotoxicity in rats. Male albino rats (N = 30) were divided into 6 groups of 5 animals each i.e. group I; Toxic control (4-acetaminophenol), group II; normal control (Normal saline), group III; Positive control (silymarin; 50 mg/kg bw) and groups IV-VI (test groups) treated with 3 chalcone analogues i-e 3a, 3f & 3 g (100, 150, 150 m

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Robin, Nicolas, Guillaume R. Coudevylle, Aymeric Guillot, and Lucette Toussaint. "French translation and validation of the Movement Imagery Questionnaire-third version (MIQ-3f)." Movement & Sport Sciences - Science & Motricité, no. 108 (2020): 23–31. http://dx.doi.org/10.1051/sm/2019035.

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Objectives: Imagery ability is a variable influencing the effectiveness of imagery practice that can be estimated by means of questionnaires. Among them, the Movement Imagery Questionnaire-Revised, translated and validated in French, is widely used by French speakers. However, it does not allow for the distinction between the two visual imagery perspectives (internal vs. external). The Movement Imagery Questionnaire-3 has been recently proposed in the English literature to differentiate between the ease of performing internal visual, external visual and kinesthetic imagery. The aim of this stu

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Sarkar, Biplab, and Anirudh Pradhan. "Choice of appropriate beam model and gantry rotational angle for low-dose gradient-based craniospinal irradiation using volumetric-modulated arc therapy." Journal of Radiotherapy in Practice 16, no. 1 (2016): 53–64. http://dx.doi.org/10.1017/s146039691600042x.

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AbstractObjectivesWe aimed to assess the impact of advanced multileaf collimator (MLC) models and flattening filter-free (3F) beam in volumetric-modulated arc therapy (VMAT)-based craniospinal irradiation (CSI).MethodsCT scans of five medulloblastoma patients who previously received CSI at our hospital were used for the present study. Patients were planned for a prescription dose of 35 Gy to craniospinal axis. A three-dimensional conformal radiotherapy (3DCRT) plan and a VMAT plan using 1 cm MLC leaf width were generated as the gold standard (reference arm). Test VMAT plans were generated usin

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Mishra, Shweta, Debashree Das, Adarsh Sahu, et al. "Electronegativity in Substituted-4(H)-quinazolinones Causes Anxiolysis without a Sedative-hypnotic Adverse Reaction in Female Wistar Rats." Central Nervous System Agents in Medicinal Chemistry 20, no. 1 (2020): 26–40. http://dx.doi.org/10.2174/1871524920666191220112545.

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Objectives: In the current study, the synthesis, characterization, and neuropharmacology of quinazolinone tethered with aromatic (3a-3i) and heteroaromatic substitution (3j, 3k, and 3l) as effective anxiolytic agents are reported. Background: Anxiety and depression are often comorbid with neurological as well as other medical maladies. Clinically known anxiolytics (Benzodiazepines) are accompanied by untoward sedation and other CNS depressive actions. The quinazolinone moiety is a privileged pharmacophore with a wide pharmacological spectrum. Herein, the synthesis, characterization, and neurop

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Jia, Chengshu, Bin Hu, Yingying Ji, et al. "Synthesis of Limonin Derivatives with Improved Anti-inflammatory and Analgesic Properties." Letters in Drug Design & Discovery 17, no. 3 (2020): 285–99. http://dx.doi.org/10.2174/1570180816666181113102359.

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Background: Limonoids represent an important class of natural products which possess a broad range of biological activities. Albeit their enormous potentials as therapeutic candidates, they usually suffer from low bioavailability, poor aqueous solubility and relatively weak biological activities which result in significant challenges in the clinic applications. Therefore, the exploration and development of novel limonin derivatives with improved drug-like properties through the structural modifications recently have attracted great attention in the biological and medicinal chemistry field. Met

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Andreeva-Gateva, P., J. Tchekalarova, K. Kamenova, et al. "Aryl Hydrocarbon Receptors in Indole Derivative Treated Mice: Neuropharmacological Perspectives." Acta Medica Bulgarica 48, no. 1 (2021): 25–33. http://dx.doi.org/10.2478/amb-2021-0004.

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Abstract Aim/objective. When applied in pharmacological doses, the indole derivative melatonin exhibits neuroactive and neuroprotective effects. Indoles and their metabolites, such as kynurenine, are ligands of aryl hydrocarbon receptors (AhR). This study aimed to evaluate the antiepileptic and analgesic activity of melatonin and two synthetic melatonin derivatives. The possible involvement of AhR and kynurenine in their neuropharmacological effects were also tested. Methods. The tested substances were: melatonin, two melatonin derivatives bearing aryl hydrocarbon moiety with either furyl or t

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Ibrahim, Elisurya, Nur Rosida, Khaerana, and Muhammad Haiqal. "Growth and result performance of 10 promising resistant lines of tungro disease in Lanrang South Sulawesi." IOP Conference Series: Earth and Environmental Science 1230, no. 1 (2023): 012132. http://dx.doi.org/10.1088/1755-1315/1230/1/012132.

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Abstract Increased rice production is constrained by various limiting factors, One of these is tungro disease, which can limit productivity. When resistant tungro varieties are available, they are regarded as an affective control tool that is also more environmental friendly. Advanced yield experiment represents a phase in the process of producing cultivars that are resistant to tungro disease. The study aimed to determine the growth and result performance of tungro-resistant lines with greater phenotypic characteristics and yield potential compared to other tungro resistant varieties. The stu

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Racané, Livio, Mirela Sedić, Nataša Ilić, Maja Aleksić, Sandra Kraljević Pavelić, and Grace Karminski-Zamola. "Novel 2-Thienyl- and 2-Benzothienyl-Substituted 6-(2-Imidazolinyl)Benzothiazoles: Synthesis; in vitro Evaluation of Antitumor Effects and Assessment of Mitochondrial Toxicity." Anti-Cancer Agents in Medicinal Chemistry 17, no. 1 (2017): 57–66. http://dx.doi.org/10.2174/1871520615666160504094753.

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Background: Differently substituted thiophenes are largely studied due to their diverse pharmacological properties, especially anticancer activity. Recent studies have reported on interesting benzothiophene compounds antitumor properties and we also recently reported on the synthesis, strong antitumor activities and DNA binding features of substituted thieno[3',2':4,5]thieno- and benzo[b]thieno[2,3-c]quinolones, containing different substituents, mostly amidino- or substituted amidino- groups. Objective: The objective of presented paper was to prepare a series of novel cationic 2-thiophene and

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Todić, Maida, Sanela Bakić, Begler Begović, Sanja Krošnjar, and Irfan Zulić. "Food and water consumption in assessment of acute oral toxicity of HEPALIP FORTE in rats." Bosnian Journal of Basic Medical Sciences 3, no. 4 (2003): 47–53. http://dx.doi.org/10.17305/bjbms.2003.3493.

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Body weight variations during toxicological testing can be one of the indicators of the test substance toxic effects. Data on food and water consumption are true indicators of the rate of growth of experimental animals (Stevens & Gallo, 1989). Daily recording of the food and water consumption was done during the acute toxicity testing of HEPALIP FORTE. The study was performed on Wistar rats. The active component of HEPALIP FORTE is EPL substance--essential phospholipids, a natural substance present in every living cell. Essential phospholipids in combination with vitamins have been used in

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Yücel, Nazlı Turan, Derya Osmaniye, Ümmühan Kandemir, Asaf Evrim Evren, Özgür Devrim Can, and Ümide Demir Özkay. "Synthesis and Antinociceptive Effect of Some Thiazole-Piperazine Derivatives: Involvement of Opioidergic System in the Activity." Molecules 26, no. 11 (2021): 3350. http://dx.doi.org/10.3390/molecules26113350.

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In this study, we aimed to design and synthesize novel molecules carrying both the thiazole and piperazine rings in their structures and to investigate their antinociceptive activity. Targeted compounds were obtained by reacting thiosemicarbazide derivative and appropriate 2-bromoacetophenone in ethanol. The structures of the obtained compounds were determined using data from various spectroscopic methods (IR, 1H-NMR, 13C-NMR, and LCMSMS). Experimental data from in vivo tests showed that test compounds 3a–3c, 3f, and 3g (50 mg/kg) significantly prolonged reaction times of animals in tail-clip

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Ibrahim, Elisurya, Fausiah T. Ladja, and I. Nyoman Widiarta. "ADVANCE YIELD TRIAL OF 10 RESISTANT RICE LINES TUNGRO DISEASE AT TUNGRO DISEASE RESEARCH STATION LANRANG SIDRAP." Agric 34, no. 1 (2022): 69–78. http://dx.doi.org/10.24246/agric.2022.v34.i1.p69-78.

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One of the factors that influence national rice production instability is an attack of tungro disease that can lead to decreased production by up to 90% even if attacking in the vegetative period can cause crop failure. To reduce tungro disease in the field can be by using resistant varieties which are the most effective components in tungro control.Advanced yield trial is one step toprocess of producing tungro resistant varieties. This research aimed to identify the results of tungro resistant strains that have higher phenotypic character and yield potential than other tungro resistant variet

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Zhao, Wennan, Mingxia Song, Yi Hua, et al. "Design, Synthesis, and Pharmacology of New Triazole-Containing Quinolinones as CNS Active Agents." Molecules 28, no. 4 (2023): 1987. http://dx.doi.org/10.3390/molecules28041987.

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Epilepsy and major depressive disorder are the two of the most common central nervous system (CNS) diseases. Clinicians and patients call for new antidepressants, antiseizure medicines, and in particular drugs for depression and epilepsy comorbidities. In this work, a dozen new triazole-quinolinones were designed, synthesized, and investigated as CNS active agents. All compounds reduced the immobility time significantly during the forced swim test (FST) in mice at the dosage of 50 mg/kg. Compounds 3f–3j gave superior performance over fluoxetine in the FST with more reductions of the immobility

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Surana, Khemchand R., Pallavi S. Jadhav, Harshada S. Shewale, et al. "Insilico and Biological Evaluation of Anti-Inflammatory Activity of synthesized Benzimidazoles Derivatives." Biosciences Biotechnology Research Asia 21, no. 3 (2024): 1241–53. http://dx.doi.org/10.13005/bbra/3300.

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ABSTRACT: We have developed a mild, easy, and highly efficient green catalyst for the synthesis of 2-substituted benzimidazole. In this study, Ace-dock and DockThore performed molecular docking of the designed benzimidazole molecules with the selected protein FAAH (PDB ID: 3LJ7). We assessed the drug's likeliness (Lipinski's rule of 5) and potential toxicity using the Protox-II software. We can confidently state that the synthesized molecules adhere to Lipinski's rule of five, given that the design molecules' properties are within acceptable limits. In comparison to the reference Ibuprofen, th

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Wu, Duo, Wei Fang, Kai Wang, et al. "Spaceborne Relative Radiometer: Instrument Design and Pre-Flight Test." Remote Sensing 15, no. 12 (2023): 3085. http://dx.doi.org/10.3390/rs15123085.

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In order to simultaneously determine the values of total solar irradiance (TSI) and the Earth’s radiation at the top of the atmosphere (TOA) on board the Fengyun-3F satellite, a spaceborne relative radiometer (SRR) was developed. It adopts a dual-channel structure, including a solar radiometer channel (SR) with an unobstructed field of view (FOV) of 1.5° and an Earth radiometer channel (ER) with a wide field of view (WFOV) of 95.3° and a diameter of about 1900 km on the ground. Before the launch, both the SR and ER were calibrated. The SR, installed on the inner frame of the solar tracker of t

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Collado-Mateo, Daniel, Francisco Javier Domínguez-Muñoz, Jose C. Adsuar, et al. "Test-Retest Intra-Session Reliability of Isokinetic Knee Strength Measurements in Obese Children." Applied Sciences 10, no. 17 (2020): 5923. http://dx.doi.org/10.3390/app10175923.

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Background: Childhood obesity is one of the most critical global health challenges. Poor knee extensor strength is associated with disability and difficulties with physical function in obese patients. The objective of this study was to evaluate the test-retest reliability of peak torque and total work in concentric flexion and concentric extension in obese children. Methods: 25 obese children aged between 6 and 11 years performed 3F maximal unilateral isokinetic repetitions with the knee extensors/flexors performing concentric actions at 60°/s. Peak torque (Nm), total work (J), and the ratio a

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Jagadapillai, Rekha, Xiaolu Qiu, Kshama Ojha, et al. "Potential Cross Talk between Autism Risk Genes and Neurovascular Molecules: A Pilot Study on Impact of Blood Brain Barrier Integrity." Cells 11, no. 14 (2022): 2211. http://dx.doi.org/10.3390/cells11142211.

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Autism Spectrum Disorder (ASD) is a common pediatric neurobiological disorder with up to 80% of genetic etiologies. Systems biology approaches may make it possible to test novel therapeutic strategies targeting molecular pathways to alleviate ASD symptoms. A clinical database of autism subjects was queried for individuals with a copy number variation (CNV) on microarray, Vineland, and Parent Concern Questionnaire scores. Pathway analyses of genes from pathogenic CNVs yielded 659 genes whose protein–protein interactions and mRNA expression mapped 121 genes with maximal antenatal expression in 1

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Banarouei, Nasimossadat, Asghar Davood, Hamed Shafaroodi, Ghazaleh Saeedi, and Abbas Shafiee. "N-arylmethylideneaminophthalimide: Design, Synthesis and Evaluation as Analgesic and Anti-inflammatory Agents." Mini-Reviews in Medicinal Chemistry 19, no. 8 (2019): 679–87. http://dx.doi.org/10.2174/1389557518666180424101009.

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Background and Objective: N-aryl derivatives of phthalimide and 4-nitro phthalimide have demonstrated cyclooxygenase inhibitory activity. Also, they possess excellent analgesic and antiinflammatory activity. In this work, a new series of N-arylmethylideneamino derivatives of phthalimide and 4-nitro phthalimide were designed and synthesized. Methods: The designed compounds were synthesized by condensation of the appropriate aldehyde and N-aminophthalimide in ethanol at room temperature at PH around 3. Their analgesic and antiinflammatory activity were evaluated by acetic acid-induced pain test

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Rokhayati, Tri, Tukiran Tanuredja, and Akhmad Jazuli. "PENGARUH PERMAINAN CROSSWORD PUZZLE TERHADAP MOTIVASI DAN HASIL BELAJAR PESERTA DIDIK SD IT HARAPAN UMAT PURBALINGGA." Tunjuk Ajar: Jurnal Penelitian Ilmu Pendidikan 3, no. 1 (2020): 65. http://dx.doi.org/10.31258/jta.v3i1.65-76.

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This research purpose to knowing affected of: 1) crosswords puzzle learning to learn motivation at third class in Harapan Umat Elementary School IT Purbalingga, 2) crosswords puzzle learning to learn result in third class. The research method was an experiment, with two group treatments that were the control group and experiment group. Group control was 3C class and the experiment group was 3F class. Data using in this research were primary and secondary data. And then data be analyzed by the Independent Sample t-test. Result of the research has shown: 1) crosswords puzzle learning significant

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Holt, Dayna M., Cindy Lewis, Kathy Klimpel, Christine Sloan, and Claire Aguda. "The Effects of Focused Nursing Education on 3F Groshong™ PICC Occlusion Rates: The Experience of One Tertiary Pediatric Care Facility." Journal of the Association for Vascular Access 15, no. 4 (2011): 213–21. http://dx.doi.org/10.2309/java.15-4-6.

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Abstract OBJECTIVE: The primary aim of this project is to reduce the incidence of 3 Fr. Groshong™ PICC occlusions through focused nursing education. BACKGROUND: The use of Peripherally Inserted Central Catheters (PICC) has become an essential tool in the care of pediatric patients. The small lumen and long length of PICCs requires specialized skill and knowledge in proper care, maintenance and flushing in order to prevent catheter occlusion and other complications. Occluded catheters compromise patient care and increase costs. Reducing the incidence of catheter occlusion, will have a significa

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Scheiber, S. M., Carol D. Robacker, and Orville M. Lindstrom. "Stem and Leaf Hardiness of 12 Abelia Taxa." Journal of Environmental Horticulture 20, no. 4 (2002): 195–200. http://dx.doi.org/10.24266/0738-2898-20.4.195.

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Abstract Twelve taxa of Abelia were evaluated using laboratory procedures to determine maximum stem and leaf hardiness and to evaluate timing of acclimation and deacclimation over a two-year period. Among the 12 Abelia taxa evaluated, ‘John Creech’ was among the hardiest taxa for both stems and leaves on the majority of test dates. Stems and leaves of ‘John Creech’ survived to at least −26C (−15F) and −21C (−6F), respectively, in January 2001. ‘Edward Goucher’ and ‘Confetti’ had the least hardy stems and leaves, respectively. Stems of ‘Edward Goucher’ survived to at least −16C (3F) in January

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Yasar, Zerbu, Susan Dewhurst, and Lawrence D. Hayes. "Peak Power Output Is Similarly Recovered After Three- and Five-Days’ Rest Following Sprint Interval Training in Young and Older Adults." Sports 7, no. 4 (2019): 94. http://dx.doi.org/10.3390/sports7040094.

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(1) Background: High-intensity interval training (HIIT) exerts effects indicative of improved health in young and older populations. However, prescribing analogous training programmes is inappropriate, as recovery from HIIT is different between young and older individuals. Sprint interval training (SIT) is a derivative of HIIT but with shorter, maximal effort intervals. Prior to prescribing this mode of training, it is imperative to understand the recovery period to prevent residual fatigue affecting subsequent adaptations. (2) Methods: Nine older (6M/3F; mean age of 70 ± 8 years) and nine you

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Kumaraswamy, Gullapelli, Ravichandar Maroju, Srinivas Bandari, Gouthami Dasari, and Gullapelli Sadanandam. "Design and synthesis of novel benzimidazoles containing 1,2,3-triazolesas in vitro, anticancer and anti-oxidant agents." Research Journal of Chemistry and Environment 25, no. 11 (2021): 104–9. http://dx.doi.org/10.25303/2511rjce104109.

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A novel series of 2-(1-((1-substitutedphenyl-1H-1,2,3- triazol-4-yl)methoxy)ethyl)-1-((1-substituted phenyl- 1H-1,2,3-triazol-4-yl)methyl)-1H-benzo[d]imidazole (3a-j)derivatives was synthesized in moderate to high yields. The structures of all the synthesized compounds were characterized by 1HNMR, 13CNMR and Mass spectroscopic methods. The title compounds were screened for their anti-oxidant activity and anti-cancer activity. The cancer activity results reveal that the compounds 3j, 3b and 3f are showing promising activity and remaining compounds exhibited moderate activity against all the tes

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Saravanabhavan, Munusamy, Ambason Franklin Ebenazer, Venkatesan Murugesan, and Marimuthu Sekar. "Synthesis, Spectroscopic Characterization and Biological Evaluation of 1-(4'-Hydroxybenzamido)-Imine-1,2,3,4-Tetrahydrocarbazole Derivatives." Journal of Advanced Physics 6, no. 1 (2017): 30–40. http://dx.doi.org/10.1166/jap.2017.1286.

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A facile synthetic approach towards 1-(4'-hydroxybenzamido)-imine-1,2,3,4-tetrahydrocarbazole derivatives 3a–g was reported via reaction of 1-oxo-1,2,3,4-tetrahydrocarbazoles 1a–g, with p-hydroxybenzhydrazide in ethanol in the presence of sufficient amount of acetic acid. The structure of all the compounds was confirmed by spectroscopic studies. The antioxidant properties of all the derivatives have also been checked against DPPH and OH radicals. Further, in vitro anticancer activities of all the synthesized compounds were investigated by MTT assay method. All the prepared analogues exhibited

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Althobaiti, Fayez, Ola A. Abu Ali, Islam Kamal, et al. "New Ionic Liquid Microemulsion-Mediated Synthesis of Silver Nanoparticles for Skin Bacterial Infection Treatments." Antibiotics 12, no. 2 (2023): 247. http://dx.doi.org/10.3390/antibiotics12020247.

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This work reports a new approach for the synthesis of extremely small monodispersed silver nanoparticles (AgNPs) (2.9–1.5) by reduction of silver nitrate in a new series of benzyl alkyl imidazolium ionic liquids (BAIILs)-based microemulsions (3a–f) as media and stabilizing agents. Interestingly, AgNPs isolated from the IILMEs bearing the bulkiest substituents (tert-butyl and n-butyl) (3f) displayed almost no nanoparticle agglomeration. In an in vitro antibacterial test against ESKAPE pathogens, all AgNPs-BAIILs had potent antibiotic activity, as reflected by antibacterial efficiency indices. F

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Tian, Tao, Hanli Wang, Sam Kwong, and C. C. Jay Kuo. "Perceptual Image Compression with Block-Level Just Noticeable Difference Prediction." ACM Transactions on Multimedia Computing, Communications, and Applications 16, no. 4 (2021): 1–15. http://dx.doi.org/10.1145/3408320.

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A block-level perceptual image compression framework is proposed in this work, including a block-level just noticeable difference (JND) prediction model and a preprocessing scheme. Specifically speaking, block-level JND values are first deduced by utilizing the OTSU method based on the variation of block-level structural similarity values between two adjacent picture-level JND values in the MCL-JCI dataset. After the JND value for each image block is generated, a convolutional neural network–based prediction model is designed to forecast block-level JND values for a given target image. Then, a

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Liu, Weipeng, Fuyan He, Wenke Yang, Zhizhou Yang, Jinshui Yao, and Hui Zhao. "Study on the Thermal Properties and Enzymatic Degradability of Chiral Polyamide-Imides Films Based on Amino Acids." Applied Sciences 9, no. 3 (2019): 578. http://dx.doi.org/10.3390/app9030578.

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Six kinds of chiral polyamide-imides (PAI3a–3f) have successfully been synthesized via direct polycondensation. The thermal properties of the materials were evaluated by the gravimetric analysis (TGA) and differential scanning calorimetry (DSC). A thermal test was conducted and showed that the polymers have good thermal stability. The Tg values were affected by the volume effect of the side groups, the internal plasticizing effect and the isolation effect. Polyamide-imides (PAIs) with L configuration showed higher Tg values than PAIs with D configuration. In the enzymatic degradation experimen

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Yang, Xiang, Wen Jin, Wang Yi, et al. "Degradation of Al 2 O 3f /SiO 2 composites exposed to Na 2 SO 4 environment and MMH/N 2 O 4 bipropellants test." International Journal of Applied Ceramic Technology 17, no. 5 (2020): 2114–22. http://dx.doi.org/10.1111/ijac.13528.

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Fernandez, Sophie, Chrystèle Charles-Delobel, Angèle Geldreich, et al. "Quantification of the 35S Promoter in DNA Extracts from Genetically Modified Organisms Using Real-Time Polymerase Chain Reaction and Specificity Assessment on Various Genetically Modified Organisms, Part I: Operating Procedure." Journal of AOAC INTERNATIONAL 88, no. 2 (2005): 547–57. http://dx.doi.org/10.1093/jaoac/88.2.547.

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Abstract A highly sensitive quantitative real-time assay targeted on the 35S promoter of a commercial genetically modified organism (GMO) was characterized (sF/sR primers) and developed for an ABI Prism® 7700 Sequence Detection System and TaqMan® chemistry. The specificity assessment and performance criteria of sF/sR assay were compared to other P35S-targeted published assays. sF/sR primers amplified a 79 base pair DNA sequence located in a part of P35S that is highly conserved among many caulimovirus strains, i.e., this consensus part of CaMV P35S is likely to be present in many GM events. Ac

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Setiyono, Setiyono, and Kunto Wibowo. "Simulation design and analysis 9-level H-bridge single phase stepdown cyclo inverter." International Journal of Power Electronics and Drive Systems (IJPEDS) 14, no. 4 (2023): 2264. http://dx.doi.org/10.11591/ijpeds.v14.i4.pp2264-2272.

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This DC-to-AC voltage converter is designed for output frequency controlled by a 9-level cascade H-bridge cyclo inverter with pulse width adjustment. The aim of the study was to determine the pattern and format of the voltage, output frequency, and Total Harmonic Distortion index of a 9-level IGBT cyclo inverter. The method used is to build a unidirectional power converter design modeling into 9 alternating levels with cyclo converter-controlled frequency settings using the Simulink MATLAB tool. The cyclo converter section is constructed with two P and N converters in a parallel arrangement. T

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Minosse, Claudia, Daniele Lapa, Antonio Coppola, et al. "Anti-HEV IgG Avidity Testing: Utility for Diagnosing Acute and Resolved Genotype 3 Infections." Viruses 13, no. 2 (2021): 236. http://dx.doi.org/10.3390/v13020236.

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European Association of the Study of the Liver (EASL) guidelines specify HEV RNA, as well as anti-HEV IgG and IgM as positive markers for acute HEV infection. HEV RNA assay sensitivity limitations may lead to false negative test results in patients with low levels of viremia. Moreover, anti-HEV IgM positivity is not a reliable indicator for distinguishing between acute and resolved infections given the ability of this antibody to persist several months after a resolved infection. Our study aims were to assess HEV IgG avidity for diagnosing acute and resolved infections, regardless of the anti-

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ME Shelke. "Synthesis and evaluation of newly1-substituted-(2H)-2-thio-4-(3-substitutedthiocarbamido-1-yl)-6-(2-imino-4-thio-5- substitutedbiureto-1-yl) 1, 2-dihydro-S-triazines as potent antimicrobial agents." GSC Biological and Pharmaceutical Sciences 13, no. 3 (2020): 109–12. http://dx.doi.org/10.30574/gscbps.2020.13.3.0245.

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The search for novel antibiotics is of immense importance in research areas around the world for agricultural, pharmaceutical, and industrial applications. The s-triazines are widely used as an important biological tool for the production of a wide range of novel secondary metabolites. In the present study, the series of 1-substituted-(2H)-2-thio-4-(3- substitutedthiocarbamido-1-yl)-6-(2-imino-4-thio- 5- substitutedbiureto-1-yl) 1,2-dihydro-s-triazine [4a(i) to 4f(iii)] have been obtained by the isomerisation of 2-(2-imino-4-thio-5- substitutedbiureto-1-yl)-4-(3- substitutedthio-carbamido-1-yl

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Vola, Marco, Juan Pablo Maureira, Vito Giovanni Ruggieri, et al. "Proof of Concept of an Endoscopic Sutureless Valve Sizer." Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 11, no. 5 (2016): 337–41. http://dx.doi.org/10.1097/imi.0000000000000313.

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Objective In this paper, we present an endoscopic expandable sizer conceived to allow thoracoscopic aortic valve replacement with a sutureless prosthesis using a dynamic sizing of the aortic annulus. Methods Ten aortic torsos were prepared using a five-trocar thoracoscopic setting. Once the aortotomy was performed and the aortic valve leaflets removed, the technical feasibility of the endoscopic sizing (introduction into the trocar, expansion into the aortic annulus, determination of the valve size, and retraction) with the device was assessed. In case of successful thoracoscopic sizing, endos

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ME, Shelke. "Synthesis and evaluation of newly1-substituted-(2H)-2-thio-4-(3-substitutedthiocarbamido-1-yl)-6-(2-imino-4-thio-5- substitutedbiureto-1-yl) 1, 2-dihydro-S-triazines as potent antimicrobial agents." GSC Biological and Pharmaceutical Sciences 13, no. 3 (2020): 109–12. https://doi.org/10.5281/zenodo.4415130.

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The search for novel antibiotics is of immense importance in research areas around the world for agricultural, pharmaceutical, and industrial applications. The s-triazines are widely used as an important biological tool for the production of a wide range of novel secondary metabolites. In the present study, the series of 1-substituted-(2H)-2-thio-4-(3- substitutedthiocarbamido-1-yl)-6-(2-imino-4-thio- 5- substitutedbiureto-1-yl) 1,2-dihydro-s-triazine [4a(i) to 4f(iii)]  have been obtained by the isomerisation of 2-(2-imino-4-thio-5- substitutedbiureto-1-yl)-4-(3- substitutedthio-carbamid

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36

Setiyono and Wibowo Kunto. "Simulation design and analysis 9-level H-bridge single phase stepdown cyclo inverter." Simulation design and analysis 9-level H-bridge single phase stepdown cycloinverter 14, no. 4 (2023): 2264–72. https://doi.org/10.11591/ijpeds.v14.i4.pp2264-2272.

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This DC-to-AC voltage converter is designed for output frequency controlled by a 9-level cascade H-bridge cyclo inverter with pulse width adjustment. The aim of the study was to determine the pattern and format of the voltage, output frequency, and Total Harmonic Distortion index of a 9-level IGBT cyclo inverter. The method used is to build a unidirectional power converter design modeling into 9 alternating levels with cyclo converter-controlled frequency settings using the Simulink MATLAB tool. The cyclo converter section is constructed with two P and N converters in a parallel arrangement. T

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Kumar, Rakesh, Ritika Sharma, Inder Kumar, et al. "Evaluation of Antiplasmodial Potential of C2 and C8 Modified Quinolines: in vitro and in silico Study." Medicinal Chemistry 15, no. 7 (2019): 790–800. http://dx.doi.org/10.2174/1573406414666181015144413.

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Background: Malaria remains a common life-threatening infectious disease across the globe due to the development of resistance by Plasmodium parasite against most antimalarial drugs. The situation demands new and effective drug candidates against Plasmodium. Objectives: The objective of this study is to design, synthesize and test novel quinoline based molecules against the malaria parasite. Methods: C2 and C8 modified quinoline analogs obtained via C-H bond functionalization approach were synthesized and evaluated for inhibition of growth of P. falciparum grown in human red blood cells using

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Zhong, Sheng, and LaDora V. Thompson. "The roles of myosin ATPase activity and myosin light chain relative content in the slowing of type IIB fibers with hindlimb unweighting in rats." American Journal of Physiology-Cell Physiology 293, no. 2 (2007): C723—C728. http://dx.doi.org/10.1152/ajpcell.00009.2007.

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We tested the hypothesis that slowing of shortening velocity generated by type IIB fibers from hindlimb-unweighted (HU) rats resulted from a reduced ATPase activity and/or a reduction in the relative content of myosin light chain 3f isoform content (MLC3f). After 2, 3, and 4 wk of HU, maximal unloaded shortening velocity ( Vo) of single permeabilized semimembranosus muscle fibers was determined by the slack test. Subsequently, the myosin heavy chain and the relative content of MLC were determined by SDS-PAGE. The ratio of MLC3f to MLC2f was determined by densitometric analysis. In addition, my

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Miladinović, Aleksandar, Christian Quaia, Miloš Ajčević, et al. "Non-Invasive Recording of Ocular-Following Responses in Children: A Promising Tool for Stereo Deficiency Evaluation." Journal of Clinical Medicine 13, no. 6 (2024): 1596. http://dx.doi.org/10.3390/jcm13061596.

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Background: The ability to merge the two retinal images to perceive depth (stereopsis) plays an important role in human vision. Its proper development requires binocular alignment and good visual acuity in both eyes during childhood. Because treatments are more effective when applied early, early diagnosis is important. Unfortunately, assessing stereo deficiencies in infants and young children remains challenging. Recently, it has been shown that ocular-following responses (OFRs; reflexive, short-latency eye movements induced by the sudden motion of a large textured pattern) are sensitive to c

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Magwaza, Nontokozo M., Garland K. More, Samantha Gildenhuys та Malose J. Mphahlele. "In Vitro α-Glucosidase and α-Amylase Inhibition, Cytotoxicity and Free Radical Scavenging Profiling of the 6-Halogeno and Mixed 6,8-Dihalogenated 2-Aryl-4-methyl-1,2-dihydroquinazoline 3-Oxides". Antioxidants 12, № 11 (2023): 1971. http://dx.doi.org/10.3390/antiox12111971.

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Series of the 6-bromo/iodo substituted 2-aryl-4-methyl-1,2-dihydroquinazoline-3-oxides and their mixed 6,8-dihalogenated (Br/I and I/Br) derivatives were evaluated for inhibitory properties against α-glucosidase and/or α-amylase activities and for cytotoxicity against breast (MCF-7) and lung (A549) cancer cell lines. The 6-bromo-2-phenyl substituted 3a and its corresponding 6-bromo-8-iodo-2-phenyl-substituted derivative 3i exhibited dual activity against α-glucosidase (IC50 = 1.08 ± 0.02 μM and 1.01 ± 0.05 μM, respectively) and α-amylase (IC50 = 5.33 ± 0.01 μM and 1.18 ± 0.06 μM, respectively)

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Jarazo, J., A. Gambini, L. Muredas, R. Fernandez-Martin, and D. Salamone. "151 HORSE EMBRYO BIOPSY: EFFECT ON PREGNANCY RATES AND SUCCESSFUL SEX DETERMINATION DEPENDING ON THE SIZE OF THE EMBRYO." Reproduction, Fertility and Development 25, no. 1 (2013): 224. http://dx.doi.org/10.1071/rdv25n1ab151.

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Commercial horse embryo transfer centers in certain parts of the world are in need of different procedures to streamline their production, for instance, by transferring only sexed embryos. A possible method to do so is PCR sex determination of biopsied embryos. The aim of this study was to (1) evaluate the impact of embryo biopsy on pregnancy rates with regard to embryo size; and (2) assess the feasibility of determining the sex of the embryo with that sample. Horse embryos were produced by artificial insemination. Embryos were recovered by transcervical uterine flush on day 7 after ovulation,

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Rechul, D., and K. Rechul. "0708 A Study To Determine Efficacy Of A Device In Anticipating Obstructive Sleep Apnea Events." Sleep 43, Supplement_1 (2020): A269—A270. http://dx.doi.org/10.1093/sleep/zsaa056.704.

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Abstract Introduction Current treatment options for obstructive sleep apnea pose multiple challenges ranging from issues with therapy adherence (i.e. PAP) to partial effectiveness (i.e. MAD) or invasiveness (i.e. implantable nerve stimulation devices). SleepMethods, Inc. designed a device that proposed to solve these issues. It consisted of two integrated mechanisms; one to anticipate the development of an obstructive event and the other to deliver therapeutic intervention to abort the process of airway collapse before it ensued. A clinical trial was conducted to test the efficacy of the syste

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Apolzan, John W., Owen T. Carmichael, Krystal M. Kirby, Sreekrishna R. Ramakrishnapillai, Robbie A. Beyl, and Corby K. Martin. "The effects of the form of sugar (solid vs. beverage) on body weight and fMRI activation: A randomized controlled pilot study." PLOS ONE 16, no. 5 (2021): e0251700. http://dx.doi.org/10.1371/journal.pone.0251700.

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Objective To test if sugar sweetened beverages (SSBs) and sugar sweetened solids (SSSs) have differential effects on body weight and reward processing in the brain. Methods In a single blind randomized controlled pilot trial (RCT), twenty participants with BMI between 20 and 40 kg/m2 were randomized to consume a 20 fluid ounce soda (SSB, 248 kcal) or the equivalent in solid form (SSS; similar to thick gelatin or gummy candy) daily. At baseline and day 28, fasting body weight and fed-state BOLD fMRI of the brain were assessed. Differences in fMRI signals between views of low-fat (LF (<30%))

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Okamura, Ken, Kaori Sato, Hiroshi Ikenoue, et al. "Primary hypothyroidism manifested in childhood with special reference to various types of reversible hypothyroidism." European Journal of Endocrinology 131, no. 2 (1994): 131–37. http://dx.doi.org/10.1530/eje.0.1310131.

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Okamura K, Sato K, Ikenoue H, Nakagawa M, Kuroda T, Yoshinari M, Fujishima M. Primary hypothyroidism manifested in childhood with special reference to various types of reversible hypothyroidism. Eur J Endocrinol 1994;131:131–7. ISSN 0804–4643 The clinical courses of 15 patients with overt primary hypothyroidism manifested in childhood were studied. Nine female patients with goitrous hypothyroidism due to chronic thyroiditis showed almost normal height and became euthyroid spontaneously during iodine restriction. The other 6 non-goitrous patients (3M and 3F) (atrophic thyroiditis in 2, lingual

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Wang, Xiujian, Tao Sun, Yongxian Hu, et al. "Chimeric Antigen Receptor T-Cell Therapy Shapes T Cell Repertoire in Chinese Patients with B-Cell Acute Lymphocyte Leukemia." Blood 132, Supplement 1 (2018): 1413. http://dx.doi.org/10.1182/blood-2018-99-115780.

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Abstract Introduction: Chimeric antigen receptor (CAR) T-cell therapy has displayed potent anti-leukemia activity in refractory/relapsed acute lymphocytic leukemia (ALL). However, the influence of CAR-T therapy on host systemic and local immunity has not been well examined. We therefore applied high-throughput T cell receptor β chain sequencing to track dynamic change of T-cell repertoire in vivo induced by CAR-T therapy in B-cell acute lymphocytic leukemia patients. Patients and Methods: Six patients with 45 samples were under observation. The samples obtained to be tested were the peripheral

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Afonkina, M. V., O. Yu Martynova, S. S. Nazarova, et al. "Predictors of rethrombosis and death in patients with COVID-19 after lower limb arterial thrombectomy for acute ischemia." Russian Journal of Cardiology 27, no. 12 (2023): 5279. http://dx.doi.org/10.15829/1560-4071-2022-5279.

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Aim. To identify predictors of rethrombosis and death in patients with coronavirus disease (COVID-19) after thrombectomy for acute lower limb ischemia.Material and methods. For the period from April 2020 to January 2022, 189 pa tients with acute arterial lower limb thrombosis and acute lower limb ischemia were included in this study. In all cases, a positive polymerase chain reaction test for SARS-CoV-2 was obtained. According to chest multislice computed tomography, bilateral multisegmental pneumonia was identified as follows: 76 patients — grade 2 (25-50% of lung tissue involvement); 52 pati

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Afonkina, M. V., O. Yu Martynova, S. S. Nazarova, et al. "Predictors of rethrombosis and death in patients with COVID-19 after lower limb arterial thrombectomy for acute ischemia." Russian Journal of Cardiology 27, no. 12 (2023): 5279. http://dx.doi.org/10.15829/1560-4071-20225279.

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Aim. To identify predictors of rethrombosis and death in patients with coronavirus disease (COVID-19) after thrombectomy for acute lower limb ischemia.Material and methods. For the period from April 2020 to January 2022, 189 pa tients with acute arterial lower limb thrombosis and acute lower limb ischemia were included in this study. In all cases, a positive polymerase chain reaction test for SARS-CoV-2 was obtained. According to chest multislice computed tomography, bilateral multisegmental pneumonia was identified as follows: 76 patients — grade 2 (25-50% of lung tissue involvement); 52 pati

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Rubio-Martinez, Araceli, Valle Recasens, Maria D. Odero, et al. "CML and Imatinib Mesylate: Response Related to Karyotype." Blood 106, no. 11 (2005): 4866. http://dx.doi.org/10.1182/blood.v106.11.4866.4866.

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Abstract Background: Imatinib mesylate (STI571), as a specific inhibitor for tyrosine kinase product of oncoprotein Bcr/Abl. Efficacy of Imatinib is questioned when other cytogenetics abnormalities associated to t(9;22) are present. We describe our experience in CML patients treated with Imatinib in one centre, evaluating hematological (HR) and cytogenetic response (CR) related to kariotype. Patients and methods: 28 patients diagnosed as having CML, 1990–2005, Imatinib 400–800 mg/d, were stratified according to cytogenetic abnormalities: Group A: t(9;22) typical in 19 patients, Group B: patien

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Santiago-Bassora, Fernanda Dutra, Aline Barnabé, Andrey dos Santos, et al. "Increased Expression of Secretory Leukocyte Protease Inhibitor (SLPI) In Mononuclear Cells From Patients with Deep Vein Thrombosis." Blood 118, no. 21 (2011): 1232. http://dx.doi.org/10.1182/blood.v118.21.1232.1232.

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Abstract Abstract 1232 Deep venous thrombosis (DVT) is a common and potentially fatal condition affecting 1% to 2% of the population worldwide, with an annual incidence of 1 in 500. Several studies have demonstrated the association between inflammation and DVT. In this study, we performed a comparative analysis of gene expression from mRNA extracted from leukocytes of 20 patients with previous DVT of the lower limbs (14F/6M; mean age: 39.7 years). An array of inflammation-related genes was selected for this study. Patients were divided in subgroups: (1) spontaneous DVT (n=10; 7F/3M). (2) risk

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Burgess, Keith R., Samuel J. E. Lucas, Katie M. E. Burgess, et al. "Increasing cerebral blood flow reduces the severity of central sleep apnea at high altitude." Journal of Applied Physiology 124, no. 5 (2018): 1341–48. http://dx.doi.org/10.1152/japplphysiol.00799.2017.

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Earlier studies have indicated an important role for cerebral blood flow in the pathophysiology of central sleep apnea (CSA) at high altitude, but were not decisive. To test the hypothesis that pharmacologically altering cerebral blood flow (CBF) without altering arterial blood gas (ABGs) values would alter the severity of CSA at high altitude, we studied 11 healthy volunteers (8M, 3F; 31 ± 7 yr) in a randomized placebo-controlled single-blind study at 5,050 m in Nepal. CBF was increased by intravenous (iv) acetazolamide (Az; 10 mg/kg) plus intravenous dobutamine (Dob) infusion (2–5 μg·kg−1·mi

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