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Journal articles on the topic 'Testicular disease'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Prokhorov, A. V. "Testicular abscess." Kazan medical journal 97, no. 4 (2016): 592–98. http://dx.doi.org/10.17750/kmj2015-592.

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In the present literature review modern view on the etiopathogenesis, clinical course, diagnosis, treatment and prognosis of testicular abscess, which is a rare disease, are described. Testicular abscess develops most often as a result of acute epididymo-orchitis (more than 80% of all cases), much rarer due to testicular inversion and injury. The etiological agent is often E. coli. The disease occurs at any age, especially in immunocompromised patients. Clinical and laboratory picture of testicular abscess has symptomatic nature and consists of local and general signs of purulent inflammation.

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2

Veselyy, M. U., and S. V. Veselyy. "Diagnostics, treatment and rehabilitation of testicular torsion in children (literature review)." Paediatric Surgery. Ukraine, no. 2(71) (June 25, 2021): 63–71. http://dx.doi.org/10.15574/ps.2021.71.63.

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Testiculat torsion (TT) is an emergency condition that is accompanied by partial or complete chorda spermatica vessels compression resulting in testicular infraction. TT main symptoms are sharp pain, scrotal hyperemia, generalized edema, nausea, vomiting and unconsciousness. However, these symptoms are characteristic of many other acute diseases of genital gland. In course of time the symptoms are less defined, which in its turn raises the issue of timely differential diagnostics. Purpose – to optimize and generalize about modern literature data on testicular torsion in children diagnostics, t

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Atis, Gokhan, Omer Faruk Memis, Hasan Samet Güngör, Ozgur Arikan, Yesim Saglican, and Turhan Caskurlu. "Testicular Polyarteritis Nodosa Mimicking Testicular Neoplasm." Scientific World JOURNAL 10 (2010): 1915–18. http://dx.doi.org/10.1100/tsw.2010.194.

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Polyarteritis nodosa (PAN) presents mostly as a systemic disease characterized by necrotizing vasculitis affecting small- and medium-sized arteries. Rarely, the inflammatory process is isolated and involves a single organ without systemic manifestations. We described the case of a 57-year-old patient with isolated testicular PAN who presented with a testicular mass mimicking a primary testicular tumor.

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ARRUDA, H. O., A. P. CEDENHO, and L. H. F. ARRUDA. "Testicular alterations in hansen's disease." Hansenologia Internationalis: hanseníase e outras doenças infecciosas 16, no. 1/2 (1991): 35–43. http://dx.doi.org/10.47878/hi.1991.v16.35229.

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Fifty testicular specimens and seminal fluid of 10 normal individuals and 24 patients with Hansen's disease were studied. General and early histological alterations, the frequency of young spermatides in tubular lumen and the measure of the diameters of 1.450 seminiferous tubules were checked. According to the results, it was not possible to establish a qualifying correlation within histological descriptions and/or a quantifying correlation within morphometry from a specific clinical group with Hansen's disease. Thus, the simultany and the variability of the findings seen in a same testis are

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5

Handelsman, David J. "Testicular Dysfunction in Systemic Disease." Endocrinology and Metabolism Clinics of North America 23, no. 4 (1994): 839–56. http://dx.doi.org/10.1016/s0889-8529(18)30071-9.

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6

Van Raamsdonk, Jeremy M., Zoe Murphy, David M. Selva, et al. "Testicular degeneration in Huntington disease." Neurobiology of Disease 26, no. 3 (2007): 512–20. http://dx.doi.org/10.1016/j.nbd.2007.01.006.

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7

Gooding, Gretchen A. W. "Ultrasound in acute testicular disease." Emergency Radiology 6, no. 5 (1999): 313–15. http://dx.doi.org/10.1007/s101400050075.

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8

Lindsay, Christopher, Lisa Boardman, and Michael Farrell. "Testicular hamartomas in Cowden disease." Journal of Clinical Ultrasound 31, no. 9 (2003): 481–83. http://dx.doi.org/10.1002/jcu.10209.

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9

Zeng, Chen, Lixiang Fang, Wei Li, and Hailan Chen. "Diagnostic efficacy and value of ultrasound in children’s scrotal testicular torsion: A retrospective analysis." Medicine 103, no. 41 (2024): e39884. http://dx.doi.org/10.1097/md.0000000000039884.

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The purpose of this study is to explore the diagnostic efficacy and value of ultrasound detection for testicular torsion in children with scrotal and testicular diseases. A total of 120 children with acute scrotal swelling and pain who were treated in our hospital from August 2017 to August 2022 were selected for preliminary diagnosis through color Doppler ultrasound diagnostic instrument examination. The final diagnosis was made through surgical or conservative treatment. At the same time, 40 children with acute epididymitis during the same period were selected as the control group, and the c

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10

Kellie, S. J., C. H. Pui, and S. B. Murphy. "Childhood non-Hodgkin's lymphoma involving the testis: clinical features and treatment outcome." Journal of Clinical Oncology 7, no. 8 (1989): 1066–70. http://dx.doi.org/10.1200/jco.1989.7.8.1066.

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Among 131 boys with advanced (stage III or IV) non-Hodgkin's lymphoma (NHL) consecutively treated at St. Jude Children's Research Hospital, testicular involvement was present at the time of diagnosis in six and as an isolated site of relapse in three. Testicular involvement was not seen in any patient with localized (stage I or II) disease. Four of the six patients with involvement at presentation are free of disease 2.9+ to 8.3+ years after diagnosis, following chemotherapy alone (three patients) or chemotherapy plus orchiectomy. Overt testicular relapse while on therapy resulted in death fro

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11

Afandiyev, Faraj, Haydar Celasin, and Serdar Culcu. "Factors that predict testicular atrophy in patients who underwent inguinal hernia repair." International Surgery Journal 7, no. 11 (2020): 3550. http://dx.doi.org/10.18203/2349-2902.isj20204422.

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Background: Some of the patients that undergo inguinal hernia repair develop testicular atrophy. Testicular atrophy development also brings about a lot of problems. In our study, we aimed to determine the rate of development of testicular atrophy and predicting factors in patients that undergo inguinal hernia repair in our hospital.Methods: Patients who underwent inguinal hernia repair in our centre from January 2017 to January 2020 were included in our study. Total number of patients was 158 divided into 2 groups i.e. group-1 (those who developed testicular atrophy after inguinal hernia repai

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12

Buetow, Stephen A. "Testicular Cancer: To Screen or Not to Screen?" Journal of Medical Screening 3, no. 1 (1996): 3–6. http://dx.doi.org/10.1177/096914139600300103.

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Objectives— To evaluate the evidence for and against routine testicular cancer screening by primary health care providers and patients (testicular self examination). Setting— Low reported frequency of routine screening for testicular cancer attributed to poor knowledge of the disease and how to screen for it. Methods— Literature based evaluation of the screening suitability of testicular cancer as a disease and palpation of the testis as the proposed screening test, and of the effectiveness of screening for testicular cancer. Results— Testicular cancer is not a major public health problem. Its

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13

Jalolov, Oybek, and Dilfuzakhon Mamarasulova. "EPIDEMIOLOGY OF TESTICULAR CANCER." Medical science of Uzbekistan, no. 2 (April 16, 2025): 120–30. https://doi.org/10.56121/2181-3612-2025-2-120-130.

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This review article, devoted to the study of the epidemiology of testicular tumors, presents the analysis of global statistics on oncological diseases, collected from the materials of the World Health Organization (WHO), especially from the International Agency for Research on Cancer, as well as from the GLOBOCAN database. The article highlights the key trends in the incidence of disease and survival of patients with testicular cancer in various regions, including the countries of America, Western, Eastern and Central Europe, as well as the states of the Middle East and East Asia, Southeast an

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14

Gochhait, Debasis, Shailesh Kekade, Jinkala Sree Rekha, and Bhawana Ashok Badhe. "Fine Needle Aspiration Cytology of Primary and Secondary Testicular Lymphoma and its Clinical Mimickers- A Definite Indication." Annals of Pathology and Laboratory Medicine 8, no. 1 (2021): C1–5. http://dx.doi.org/10.21276/apalm.2914.

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Albeit being rare, the testicular lymphoma is the most common testicular malignancy in elders. In early stages, its symptoms are non-specific and can mimic other underlying diseases. The available knowledge of cytology on this entity is not adequate. In case when a clinician comes across a testicular enlargement case, a decision has to be made when to send the patient for FNAC. Similarly, the pathologist who is assessing the patient should also make a decision whether to perform Fine Needle Aspiration Cytology (FNAC) on the patient or not, and what morphology is expected on cytological smears

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15

Shurbaji, Muhammad S., and Jonathan I. Epstein. "Testicular vasculitis: Implications for systemic disease." Human Pathology 19, no. 2 (1988): 186–89. http://dx.doi.org/10.1016/s0046-8177(88)80347-2.

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16

Kabani, Amin, Ari Joffe, Mireille LeMay, and Taj Jadavji. "Testicular findings early in Kawasaki disease." Progress in Pediatric Cardiology 1, no. 1 (1992): 83. http://dx.doi.org/10.1016/s1058-9813(06)80074-3.

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17

Bhatia, Komal, Ashok Kumar Vaid, Sachin Gupta, Dinesh Chandra Doval, and Vineet Talwar. "Primary testicular non-Hodgkin's lymphoma: a review article." Sao Paulo Medical Journal 125, no. 5 (2007): 286–88. http://dx.doi.org/10.1590/s1516-31802007000500007.

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Primary testicular non-Hodgkin's lymphoma was first described as a clinical entity in 1866. It is a rare disease and accounts for 1% of all non-Hodgkin's lymphoma, 2% of all extranodal lymphomas and 5% of all testicular neoplasms. It is the most common testicular tumor in males between sixty and eighty years of age. Testicular non-Hodgkin's lymphoma is unique in its high incidence of bilateral involvement (8-38%), and it is also the most common bilateral testicular tumor. Testicular non-Hodgkin's lymphoma has a predilection for spreading to non-contiguous extranodal sites, especially the centr

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18

O'Connor, A., A. Dias, and C. Timon. "Role of neck dissection for metastatic nonseminomatous testicular carcinoma: case report and literature review." Journal of Laryngology & Otology 127, no. 10 (2013): 1038–39. http://dx.doi.org/10.1017/s0022215113002090.

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AbstractObjectives:To review the incidence, treatment and prognosis of testicular carcinoma metastatic to the neck, and to propose a selective neck dissection be performed for residual disease post-chemotherapy.Case report:A 17-year-old young man with metastatic testicular carcinoma presented with a left neck mass. A palpable neck mass is the initial sign in approximately 5 per cent of cases of metastatic testicular teratoma. Approximately 30 per cent of patients with advanced-stage testicular cancer have extra-retroperitoneal disease post-chemotherapy, which requires resection. The presented

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19

Li, Jenny, and Nicholas Power. "Scrotal recurrence of germ cell tumour in a non-violated scrotum." Canadian Urological Association Journal 10, no. 11-12 (2016): 388. http://dx.doi.org/10.5489/cuaj.3505.

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Testicular cancer is the most common cancer diagnosis in males aged 15‒30 years. For over a century, radical inguinal orchiectomy has been the standard of care for initial treatment of testicular cancer. This approach is preferred over trans-scrotal interventions, in an effort to avoid tumour seeding, spermatic cord invasion, and disturbance to lymphatic drainage. Scrotal violation is defined as any trans-scrotal intervention that may impact spread of disease in testicular cancer, including scrotal orchiectomy, fine-needle aspiration, and testicular biopsy. Studies have shown statistically sig

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20

Yule, Terecita D., Cherrie A. Mahi-Brown, and Kenneth S. K. Tung. "Role of testicular autoantigens and influence of lymphokines in testicular autoimmune disease." Journal of Reproductive Immunology 18, no. 1 (1990): 89–103. http://dx.doi.org/10.1016/0165-0378(90)90026-3.

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21

Bumbasirevic, Uros, Nebojsa Bojanic, Marija Pljesa-Ercegovac, et al. "The Polymorphisms of Genes Encoding Catalytic Antioxidant Proteins Modulate the Susceptibility and Progression of Testicular Germ Cell Tumor." Cancers 14, no. 4 (2022): 1068. http://dx.doi.org/10.3390/cancers14041068.

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The simultaneous analysis of redox biomarkers and polymorphisms encoding for regulatory and catalytic antioxidant proteins was performed in order to evaluate their potential role in the development of testicular germ cell tumor (GCT), as well as the progression of the disease. NRF2 (rs6721961), GSTM3 (rs1332018), SOD2 (rs4880) and GPX3 (rs8177412) polymorphisms were assessed in 88 patients with testicular GCT (52 with seminoma) and 88 age-matched controls. The plasma levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG), thiol groups and the plasma activity of glutathione peroxidase were measured. A

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22

Molnár, Zsuzsanna, Mátyás Benyó, Zsuzsa Bazsáné Kassai, Írisz Lévai, Attila Varga, and Attila Jakab. "Influence of malignant tumors occurring in the reproductive age on spermiogenesis: Studies on patients with testicular tumor and lymphoma." Orvosi Hetilap 155, no. 33 (2014): 1306–11. http://dx.doi.org/10.1556/oh.2014.29951.

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Introduction: The application of chemo- and radiotherapy results in good survival prognosis for young men with malignant tumors, but long-term gonadoxic effect has to be considered. In addition, malignant disease itself has a negative impact on spermiogenesis. Aim: The aim of the authors was to examine the spermiogenetic effect of the most common tumors occurring in the reproductive age in men: testicular cancer, Hodgkin disease and non-Hodgkin disease. Method: Spermiogram of men with testicular cancer (N = 68), Hodgkin disease (N = 37) and non-Hodgkin disease (N = 14) who were referred for sp

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23

Baxter, Mark A., Graham MacDonald, Jahangeer Malik, et al. "Testicular cancer: improving outcomes with national quality performance indicators." BMJ Open Quality 9, no. 1 (2020): e000726. http://dx.doi.org/10.1136/bmjoq-2019-000726.

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Testicular cancer is the most common malignancy in young adult men. The prognosis is excellent in limited disease and cure is possible even in advanced disease. Quality performance indicators (QPI) are used in many developed countries as a measure of healthcare performance. We report and discuss the development of a national set of QPIs in Scotland for testicular cancer as a method of gathering demographic data and driving improvement in nationwide testicular cancer outcomes.

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24

Chatar, Achraf, Abdelaziz Amoch, Mohamed Amine Lakmichi, Zakaria Dahami, and Ismail Sarf. "Isolated Hydatid Cyst: A Misleading Diagnosis." Société Internationale d’Urologie Journal 5, no. 4 (2024): 263–65. http://dx.doi.org/10.3390/siuj5040041.

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Cystic hydatid disease is an endemic disease caused by the larval form of Echinococcus granulosis. It is especially evident in the liver, lungs, and kidney. Testicular hydatidosis is extremely rare. A case of a hydatid cyst of the testis is reported that was misdiagnosed clinically as a testicular hydrocele. Echinococcosis should be considered in the differential diagnosis of testicular masses especially in endemic countries. Treatment is mainly surgical and, with proper diagnosis and treatment, the prognosis is good.

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Chaudhari, Vipul, Simran Jatin Thakkar, Namita Padwal, and Niteen Karnik. "Idiopathic multicentric Castleman disease." Journal of Cancer Research and Therapeutics 20, no. 5 (2023): 1602–4. http://dx.doi.org/10.4103/jcrt.jcrt_2190_22.

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ABSTRACT An elderly man presented with fever and chills for six months, associated with loss of appetite and weight loss, bilateral edema, and non-tender inguinal lymphadenopathy. The left-sided testicle was bulky, firm, and non-tender. Investigations revealed anemia, leukopenia, elevated erythrocyte sedimentation rate, and hypergammaglobulinemia. Ultrasound of the abdomen revealed multiple enlarged necrotic lymph nodes in the periaortic, preaortic, precaval, and bilateral pelvic regions. Fine-needle aspiration cytology (FNAC) of the inguinal nodes showed no acid-fast bacilli (AFB). However, e

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Romics, Miklós, Judit Demeter, Imre Romics, and Péter Nyirády. "Diagnosis and treatment of primary testicular non-Hodgkin lymphoma." Orvosi Hetilap 155, no. 2 (2014): 69–71. http://dx.doi.org/10.1556/oh.2014.29798.

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The primary testicular non-Hodgkin lymphoma, which has been first described in 1866, is a very uncommon type of urological neoplasia occuring mostly in the elderly ages. It only gives 5% of the testicular tumors, 2% of extranodal lymphomas, and barely 1% of all non-Hodgkin diseases. Patients with testicular non-Hodgkin lymphomas need prompt multidisciplinary aid because without treatment the outcome can be unfavorable. The authors discuss the attributes, diagnostic modalities and treatment options of the primary testicular non-Hodgkin lymphoma and present a case of a 68-year-old patient who un

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Anguiano-García, Sergio A., and Andrea Ledesma-Blanhir. "Testicular teratoma in scrotal trauma: a case report." International Surgery Journal 10, no. 11 (2023): 1820–23. http://dx.doi.org/10.18203/2349-2902.isj20233347.

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Testicular teratoma as first described by Virchow in 1863 may be one of the oldest known tumours. Patients usually course asymptomatic, early signs consist of testicular enlargement. We present a case of a male patient in his fourth decade of life with no prior documentation of testicular enlargement, he suffers from scrotal trauma presenting, pain, dysuria, scrotal swelling and nausea. Tumoral markers were normal and ultrasound revealed right testicle with cystic degeneration and malignant aspect. Radical orchiectomy was performed revealing a pure testicular teratoma. This disease may change

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28

Suleymanov, S. I., Z. A. Kadyrov, D. A. Fedorov, A. S. Babkin, A. M. Aguzarov, and A. V. Babkina. "Thrombosis of the testicular vein with outcome in testicular infarction. Clinical case." Andrology and Genital Surgery 24, no. 3 (2023): 101–6. http://dx.doi.org/10.17650/2070-9781-2023-24-3-101-106.

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This article describes the clinical manifestations of testicular vein thrombosis, methods for diagnosing this disease, as well as possible complications and methods for their elimination.The presented nosology is a rare pathology with a clinical picture of an acute scrotum that can develop at any age. In most cases, the symptom group of acute scrotum syndrome is caused by orchiepididymitis, testicular torsion. In a small percentage of cases, according to the results of the examination, testicular vein thrombosis is detected.As an example, clearly illustrating the treatment options for a compli

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29

Beyazal, Mehmet, Fatma Beyazal Çeliker, Mehmet Fatih İnecikli, Maksude Esra Kadioğlu, Hasan Rıza Aydın, and Tuğba Durakoğlugil. "The Monitoring of Preoperative External Detorsion with Diffusion-Weighted Imaging in a Patient with Acute Testicular Torsion." Case Reports in Radiology 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/3702873.

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Testicular torsion is one of the main causes of acute scrotum and may result in permanent damage of the testicular tissue. Color Doppler imaging has been frequently used in the diagnosis of testicular torsion and posttreatment follow-up period of the disease. There are some studies reporting the value and usefulness of diffusion-weighted imaging in the diagnosis of testicular torsion. However, to the best of our knowledge, there is no report regarding the monitoring of preoperative external detorsion in testicular torsion with diffusion-weighted imaging examination. In this article, diffusion-

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Faniev, M. V., S. I. Suleymanov, Z. A. Kadyrov, D. M. Уagudaev, and M. A. Giyoev. "Typical errors in the diagnosis and treatment of testicular torsion in adults. Clinical observation." Andrology and Genital Surgery 24, no. 2 (2023): 121–25. http://dx.doi.org/10.17650/2070-9781-2023-24-2-121-125.

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Testicular torsion refers to diseases of the acute scrotum group and requires early diagnosis and emergency surgical care. Despite the characteristic clinical signs, sometimes there are difficulties in diagnosis, which leads to delayed treatment and irreversible damage to the testicle.The article describes a clinical case of testicular torsion in a young patient with errors in diagnosis, which led to the removal of the testicle. As a result of a diagnostic error – an incorrect collected anamnesis and not timely execution of ultrasound dopplerography, conservative treatment for epididymoorchiti

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Resorlu, Berkan, Kadir Onem, and Rustu Cankon Germiyanoglu. "Primary testicular osteosarcoma." Urologia Journal 85, no. 2 (2018): 44–45. http://dx.doi.org/10.1177/0391560317749429.

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Primary testicular osteosarcoma is an extremely rare type of malignant tumor, and to our knowledge, only two other cases have previously been reported in the medical literature. A 63-year-old man, who presented with a large painless left inguinal and scrotal mass, underwent radical orchiectomy. Pathological examination was suggestive of testiscular osteosarcoma. The patient received no adjuvant therapy and after 12 months of follow-up, the patient remains free of disease.

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Azandariani, Ahmad Rezayi, Leili Ebrahimi, and Sedigheh Saedi. "Testicular Lipomatosis without Evidence of Cowden’s Disease." Case Reports in Clinical Medicine 04, no. 12 (2015): 364–68. http://dx.doi.org/10.4236/crcm.2015.412074.

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33

Subramanyam, BR, SC Horii, and S. Hilton. "Diffuse testicular disease: sonographic features and significance." American Journal of Roentgenology 145, no. 6 (1985): 1221–24. http://dx.doi.org/10.2214/ajr.145.6.1221.

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&NA;. "CV disease: complication of testicular cancer treatment?" Reactions Weekly &NA;, no. 956 (2003): 5. http://dx.doi.org/10.2165/00128415-200309560-00015.

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CHUBB, CURTIS. "Testicular Function of Mice with Kidney Disease." Annals of the New York Academy of Sciences 513, no. 1 Cell Biology (1987): 520–22. http://dx.doi.org/10.1111/j.1749-6632.1987.tb25094.x.

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36

Withington, John. "Testicular cancer outcome inequality: a curable disease?" BJU International 124, no. 3 (2019): 359–60. http://dx.doi.org/10.1111/bju.14860.

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HOLMES, NICHOLAS M., and CHRISTOPHER J. KANE. "TESTICULAR INFARCTION ASSOCIATED WITH SICKLE CELL DISEASE." Journal of Urology 160, no. 1 (1998): 130. http://dx.doi.org/10.1016/s0022-5347(01)63058-1.

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La Vignera, Sandro, Roberto Vita, Rosita A. Condorelli, et al. "Impact of thyroid disease on testicular function." Endocrine 58, no. 3 (2017): 397–407. http://dx.doi.org/10.1007/s12020-017-1303-8.

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Venkatanarasimha, Nanda, Shakira Hilmy, and Simon Freeman. "Case 175: Testicular Lipomatosis in Cowden Disease." Radiology 261, no. 2 (2011): 654–58. http://dx.doi.org/10.1148/radiol.11091151.

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Groot-Loonen, J. J., P. A. Voûte, and J. De Kraker. "Testicular tumor concomitant with von Recklinghausen's disease." Medical and Pediatric Oncology 16, no. 2 (1988): 116–17. http://dx.doi.org/10.1002/mpo.2950160210.

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41

Albuquerque, J., D. N. Silva, L. Leal-Costa, et al. "Thromboembolic disease in testicular germ cell tumors." European Urology Open Science 45 (November 2022): S213. http://dx.doi.org/10.1016/s2666-1683(22)02563-0.

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Sharma, Amit, Deepak Biswal, Satyadeo Sharma, and Kishore Roy. "Report of testicular tumour in a toddler: management beyond the testis." Therapeutic Advances in Urology 15 (January 2023): 175628722211483. http://dx.doi.org/10.1177/17562872221148382.

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Testicular tumours in prepubertal children tend to be pure yolk sac tumours detected in stage I and have good prognosis. We describe a case of a 2-year old male child with a mixed testicular tumour presenting with stage IIC disease and managed with retroperitoneal lymph node dissection for residual retroperitoneal disease post adjuvant chemotherapy.

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Bloom, J. R., P. Fobair, E. Gritz, et al. "Psychosocial outcomes of cancer: a comparative analysis of Hodgkin's disease and testicular cancer." Journal of Clinical Oncology 11, no. 5 (1993): 979–88. http://dx.doi.org/10.1200/jco.1993.11.5.979.

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PURPOSE The psychosocial outcomes of testicular cancer and Hodgkin's disease were compared to test our hypotheses that more specific dysfunction and less hiding of symptoms would be found in the former group, as cancer visibly affects a sexual organ. Since those with Hodgkin's disease could more easily deny the disease, poorer psychosocial adjustment was predicted. PATIENTS AND METHODS The sample consists of 85 men with Hodgkin's disease and 88 men with testicular cancer (seminomatous, n = 39; or nonseminomatous, n = 49). They were interviewed once, at least 1 year following the end of treatme

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Yazici, Sertac, Dario Del Biondo, Giorgio Napodano, et al. "Risk Factors for Testicular Cancer: Environment, Genes and Infections—Is It All?" Medicina 59, no. 4 (2023): 724. http://dx.doi.org/10.3390/medicina59040724.

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The incidence of testicular cancer is steadily increasing over the past several decades in different developed countries. If on one side better diagnosis and treatment have shone a light on this disease, on the other side, differently from other malignant diseases, few risk factors have been identified. The reasons for the increase in testicular cancer are however unknown while risk factors are still poorly understood. Several studies have suggested that exposure to various factors in adolescence as well as in adulthood could be linked to the development of testicular cancer. Nevertheless, the

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Aksglaede, L., and A. Juul. "Therapy of endocrine disease: Testicular function and fertility in men with Klinefelter syndrome: a review." European Journal of Endocrinology 168, no. 4 (2013): R67—R76. http://dx.doi.org/10.1530/eje-12-0934.

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Klinefelter syndrome, 47,XXY (KS), is the most frequent sex chromosome aberration in males, affecting 1 in 660 newborn boys. The syndrome is characterized by testicular destruction with extensive fibrosis and hyalinization of the seminiferous tubules resulting in small testes, hypergonadotropic hypogonadism, and azoospermia in the majority of cases. Until recently, infertility was considered an untreatable condition in KS. However, with the development of new advanced assisted reproductive techniques such as testicular sperm extraction (TESE) combined with ICSI it seems that KS patients should

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Victor, Abhulimen, and Danagogo Okigbeye. "Testicular Cancer - The Great Masquerader." American Journal of Health, Medicine and Nursing Practice 7, no. 10 (2022): 29–33. http://dx.doi.org/10.47672/ajhmn.1164.

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Purpose: Testicular cancer is rare with increasing incidence worldwide. Testicular cancer can mimic many other diseases leading to delay in diagnosis. Delays in diagnosis and management of testicular cancer are associated with advanced stage, increased morbidity and poor prognosis. This case report aims to highlight a case of testicular cancer who presented with metastasis due to delays in testicular cancer diagnosis and ways to improve diagnosis. Methodology: The study focused on a 17-year-old boy presented with severe intermittent abdominal pain for a month. He was reviewed by the gene

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Chu, Eric Chun Pu. "Taming of the Testicular Pain Complicating Lumbar Disc Herniation With Spinal Manipulation." American Journal of Men's Health 14, no. 4 (2020): 155798832094935. http://dx.doi.org/10.1177/1557988320949358.

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Degenerative disease of the lumbar spine is often ignored as a potential cause of testicular pain because the exact link between the two remains uncertain. This article reports the case of a 60-year-old man with a 3-year history of low back pain and unexplained right testicular pain for 2 years. Painful symptoms were negatively affecting his social, physical, and sexual functions. After failure to achieve pain relief through multiple types of therapy, the patient sought chiropractic treatment for his condition. Lumbar spine magnetic resonance imaging (MRI) revealed disc protrusion at the L1/L2

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Lin, Diwei, Amanda Jia Hui Tan, and Rajinder Singh-Rai. "A Literature Review and Case Report of Metastatic Pure Choriocarcinoma." Case Reports in Oncological Medicine 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/345018.

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In 2012, testicular cancer was estimated to account for 940 disability adjusted life years in Australia; of these, 450 were years lost due to premature death and 500 were years of healthy life lost due to disease, disability, or injury (Australian Institute of Health and Welfare and Australasian Association of Cancer Registries, 2012). Testicular choriocarcinoma is one of the rarest variants of testicular germ cell tumours, accounting for less than 1% of testicular germ cell tumours and only about 0.19% of all testicular tumours. Management involves radical orchidectomy and chemotherapy. Even

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Jain, Sanchay, Deepa Singh, and Suruchi Jain. "Tc-99m MDP Scan with Unusual and Isolated Skeletal Metastasis in Skull Bone in a Case of Testicular Seminoma." Indian Journal of Nuclear Medicine 38, no. 3 (2023): 289–91. http://dx.doi.org/10.4103/ijnm.ijnm_197_22.

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Seminomas are common germ cell tumors (GCT) that may arise in the testes as well as in extra testicular locations such as mediastinum with/without testicular tumor. Testicular tumors are usually detected early due to their location and presentation as testicular mass. The overall prognosis of the seminomatous GCTs is good with surgery as the mainstay of treatment in localized disease. Bone metastases, especially when present in isolation are exceedingly rare in seminoma. Here, we present a rare case of skull bone metastasis in a case of testicular seminoma which was detected on technetium-99m

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Amir Shaghaghi, Mandana, Brent Murphy, and Peter Eck. "The SLC2A14 gene: genomic locus, tissue expression, splice variants, and subcellular localization of the protein." Biochemistry and Cell Biology 94, no. 4 (2016): 331–35. http://dx.doi.org/10.1139/bcb-2015-0089.

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The SLC2A14 gene encodes for GLUT14, an orphan member of the facilitated membrane glucose transporter family, which was originally described to be exclusively expressed in human testis. However, genetic variations in SLC2A14 are associated with chronic diseases such as Alzheimer’s disease and Inflammatory Bowel Disease, which cannot be explained by a strictly testicular expression. Therefore we analyzed available information on the SLC2A14 gene to update knowledge of the locus and its encoded products. This report presents an expanded SLC2A14 gene locus and a more diverse tissue expression, co

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