Relevant bibliographies by topics / Testicular toxicity

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Testicular toxicity'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Testicular toxicity"

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Rovira, Jordi, Fritz Diekmann, María José Ramírez-Bajo, Elisenda Bañón-Maneus, Daniel Moya-Rull, and Josep M. Campistol. "Sirolimus-Associated Testicular Toxicity." Transplantation Journal 93, no. 9 (2012): 874–79. http://dx.doi.org/10.1097/tp.0b013e31824bf1f0.

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Chatani, Fumio. "Drug-induced testicular toxicity." Folia Pharmacologica Japonica 133, no. 2 (2009): 82–86. http://dx.doi.org/10.1254/fpj.133.82.

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Mostofi, F. K. "Commentary On Testicular Toxicity." Toxicologic Pathology 25, no. 4 (1997): 418. http://dx.doi.org/10.1177/019262339702500416.

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Takahashi, Michihito, and Hajime Matsui. "Mechanisms of testicular toxicity." Journal of Toxicologic Pathology 6, no. 2 (1993): 161–74. http://dx.doi.org/10.1293/tox.6.161.

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Shigeru, Suna, and Jitsunari Fumihiko. "Effect of caffeine and ethanol intake on di (2-ethylhexyl) phthalate (DEHP)-induced testicular atrophy." World Journal of Biology Pharmacy and Health Sciences 13, no. 3 (2023): 252–61. https://doi.org/10.5281/zenodo.8036103.

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<strong>Background:</strong>&nbsp;Di(2-ethylhexyl) phthalate (DEHP) is the most widely used polyvinyl chloride (PVC) plasticizer. Therefore, DEHP pollution is spreading all over the world. In recent years, it has attracted attention as an endocrine disrupting chemical. In animal experiments using rodents, testicular toxicity has been confirmed by feeding diets containing DEHP. Mono(2-ethylhexyl) phthalate (MEHP), a potent oxidative stressor, is thought to be directly involved in testicular toxicity. On the other hand, caffeine and ethanol, which are hydroxyl radical scavengers, are taken in re
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Levi, Mattan, Moran Tzabari, Naphtali Savion, Salomon M. Stemmer, Ruth Shalgi, and Irit Ben-Aharon. "Dexrazoxane exacerbates doxorubicin-induced testicular toxicity." REPRODUCTION 150, no. 4 (2015): 357–66. http://dx.doi.org/10.1530/rep-15-0129.

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Infertility induced by anti-cancer treatments pose a major concern for cancer survivors. Doxorubicin (DXR) has been previously shown to exert toxic effects on the testicular germinal epithelium. Based upon the cardioprotective traits of dexrazoxane (DEX), we studied its potential effect in reducing DXR-induced testicular toxicity. Male mice were injected with 5 mg/kg DXR, 100 mg/kg DEX, combination of both or saline (control) and sacrificed either 1, 3 or 6 months later. Testes were excised and further processed. Glutathione and apoptosis assays were performed to determine oxidative stress. Im
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Gugic, Jasenka, Lorna Zadravec Zaletel, and Irena Oblak. "Treatment-related cardiovascular toxicity in long-term survivors of testicular cancer." Radiology and Oncology 51, no. 2 (2017): 221–27. http://dx.doi.org/10.1515/raon-2016-0021.

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Abstract Backgrounds Testicular cancer is the most common malignancy in young men. Considering increasing incidence, exceptionally high cure rate, as well as long life expectancy, assessment of long term toxicity in testicular cancer survivors is of great importance. In the last decades a major effort has been made in order to reduce toxicity of treatment, while maintaining its high effectiveness. Conclusions Actual knowledge on treatment toxicity is based on outdated treatment modalities. Hopefully, modern treatment modalities could reduce toxicity, but, there is no firm confirmation for that
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Aldossary, Sara Abdulraman. "Sesamol counter act toxicity of arsenic on testicular tissues." Journal of medical pharmaceutical and allied sciences 11, no. 5 (2022): 5259–63. http://dx.doi.org/10.55522/jmpas.v11i5.3794.

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The main aim of the study includes analyzing the protective effects of sesamol of testicular in arsenic-induced toxicity. Primarily there have been different treatments and sample preparation methods that includethe mixing of drugs seasonal and arsenic, as they were immersed into the aqueous solution of tween 80 and further arsenic stabilisation was done using gum of 0.2%. A total of four groups, each group having 8 rats selected. Testicular catalase is decreased in arsenic treated rats whereas testicular (Glutathione synthetase) GSH, testicular (nitric oxide) NO and testicular malondialdehyde
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Ichihara, Gaku, Nobuyuki Asaeda, Toshihiko Kumazawa, et al. "Testicular Toxicity of 2‐Bromopropane." Journal of Occupational Health 38, no. 4 (1996): 205–6. http://dx.doi.org/10.1539/joh.38.205.

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Ohara, Masao. "ULTRASTRUCTURAL STUDY OF TESTICULAR TOXICITY." Japanese Journal of Urology 79, no. 5 (1988): 788–98. http://dx.doi.org/10.5980/jpnjurol1928.79.5_788.

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Dissertations / Theses on the topic "Testicular toxicity"

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Elkin, Naomi D. "Evaluation of biomarkers for testicular toxicity." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4412.

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Non-clinical safety assessment is essential during the drug development process in the pharmaceutical industry, and involves numerous, detailed in vitro and in vivo toxicology tests (general, reproductive and genetic), and safety pharmacology studies. The testis is a common organ for adverse drug effects leading to attrition of potential compounds. It would, therefore, be useful to detect testicular toxicity as early as possible in the drug development process. Histopathology is the standard method for assessing testis toxicity, but a biomarker for ‘early warning’ detection of testicular toxic
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Adegoke, Oluwajoba Oluwapelumi. "Transcriptional and post-transcriptional regulation in testicular toxicity." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/31979.

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The control of gene expression occurs at multiple levels one of which is controlled by epigenetic regulation. In this work, it was hypothesised that changes in DNA methylation (transcriptional level) and miRNA expression (post-transcriptional level) might be involved in the mechanism of compound-induced testicular toxicity. mRNA and miRNA analysis of mouse testis was performed following exposure to dibutyl phthalate, 17β-estradiol and doxorubicin. Pathway analysis of transcriptional changes revealed all three chemicals interfered with the steroidogenic pathway, with further modulation of oxida
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Wahed, I. A. "Testicular toxicity of standard and investigational anti-cancer drugs." Thesis, University of Bradford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380578.

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Piner, J. A. "The novel testicular toxicity of a 5HT-1 receptor agonist." Thesis, University of Edinburgh, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.660620.

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The aims of the work presented in this Thesis were to establish the nature and mechanism of the testicular and epididymal toxicity in Charles River Wistar rats, at least 10 weeks of age, after administration of high dosages of GR403370D, a 5HT-1 receptor agonist that was under development by Glaxo Wellcome for the potential relief of migrainous headaches. Initial investigations used a detailed morphological examination of perfusion-fixed tissues which were confirmed and/or further characterised using image analysis. The testicular vasculature was implicated as the initial target, since a reduc
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Rajeh, Nisreen A. "Acrylamide-induced testicular toxicity in rat: modulatory effect of 5-aminosalicylic acid." Thesis, University of Surrey, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583321.

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Acrylamide (AA) is a vinyl monomer that has many applications in chemical industries. The aim of this work was to assess the reproductive toxicity of AA and clarity its underlying mechanism of action in rat; in particular, whether AA or its reactive metabolite glycidamide is responsible for the majority of the noted adverse effects. Moreover, the protective effect of 5-aminosalicylic acid (5-ASA) against AA testicular and genotoxicity was investigated. Acrylamide gavaged at doses from 5-60mg/kg daily for 5 consecutive days caused dose- dependent toxicity. Light microscopy examination showed mu
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Roberts, A. "The metabolism and pharmacokinetics of cyclohexylamine and their relevance to testicular toxicity." Thesis, University of Southampton, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235156.

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Martin, Lisa Joy. "FK506, an inhibitor of calcineurin, prevents cadmium-induced testicular toxicity in mice." Diss., Restricted to subscribing institutions, 2007. http://proquest.umi.com/pqdweb?did=1320950781&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Ludwig, Sophie. "Comportement d'un "Perturbateur Endocrinien" et d'un "non Perturbateur Endocrinien" vis à vis de la toxicité testiculaire chez le rat." Phd thesis, Université Paris Sud - Paris XI, 2011. http://tel.archives-ouvertes.fr/tel-00658641.

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Depuis plusieurs années, des agents exogènes environnementaux appelés perturbateurs endocriniens (PE), sont soupçonnés d'interférer avec les fonctions essentielles de reproduction et de développement chez de nombreux organismes vivants. Au travers de ce travail, nous avons tenté de combler certaines lacunes afin de mieux comprendre les dangers pour l'Homme posés par ces produits. Des études ont été menées visant à caractériser la toxicité testiculaire, chez le rat adulte, induite par des composés aux mécanismes d'action toxique divers (PE et non PE), ceci dans le but d'établir in fine l'existe
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Lesné, Laurianne. "Antiépileptiques et antalgiques pendant la grossesse et homéostasie du testicule foetal humain." Electronic Thesis or Diss., Université de Rennes (2023-....), 2023. http://www.theses.fr/2023URENB075.

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Le développement fœtal est une période particulièrement vulnérable aux déséquilibres du milieu dans lequel il se déroule. Le testicule fœtal joue un rôle capital dans la masculinisation des organes reproducteurs via sa fonction endocrine, et toute altération peut engendrer un spectre de malformations pouvant impacter la fertilité future de l’homme. Au cours du développement, l’embryon puis le fœtus va être exposé à un l’environnement chimique complexe qu’est l’exposome maternel. Parmi les familles de substances constituant l’exposome se trouvent les médicaments que la femme enceinte consomme p
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Azouri, Tannous Hayat. "Étude de la toxicité de deux complexes du platine : description d'un nouveau modèle d'appréciation de la toxicité testiculaire." Paris 11, 1989. http://www.theses.fr/1989PA114822.

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Books on the topic "Testicular toxicity"

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1952-, Scialli Anthony R., and Clegg Eric D, eds. Reversibility in testicular toxicity assessment. CRC Press, 1992.

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2

Sjoberg, Per. Studies on the disposition and testicular toxicity of di-(2-ethylhexyl) phthalate. Sveriges Lantbruksuniversitet, 1985.

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Wahed, Ismaeel Abrahim. Testicular toxicity of standard and investigational anti-cancer drugs: Cytotoxic effects ofstandard and investigational anti-cancer drugs on the histology and physiology of the mouse testis. 1988.

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Book chapters on the topic "Testicular toxicity"

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Hoyes, Katharine P., N. Colin Jackson, Harold Jackson, Harbans L. Sharma, Jolyon H. Hendry, and Ian D. Morris. "Genotoxic Consequences of Testicular Localization of Indium-114m." In Male-Mediated Developmental Toxicity. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-1877-8_28.

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Robaire, Bernard, and Barbara F. Hales. "Post-Testicular Mechanisms of Male-Mediated Developmental Toxicity." In Male-Mediated Developmental Toxicity. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-1877-8_9.

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Dybing, E., E. J. Soderlund, M. Låg, et al. "Testicular Metabolism and Toxicity of Halogenated Propanes." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5877-0_63.

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Knight, Julia A., Loraine D. Marrett, and Hannah K. Weir. "Occupations of Fathers before Conception and the Risk of Testicular Cancer in their Sons." In Male-Mediated Developmental Toxicity. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-1877-8_31.

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Rune, Gabriele M., Jutta Hartmann, and Philippe De Souza. "Quantitative Morphological Tests for Evaluation of Testicular Toxicity." In Risk Assessment of Prenatally-Induced Adverse Health Effects. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77753-0_29.

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Lloyd, S. C., and P. M. D. Foster. "1,3-Dinitrobenzene: Toxicity and Metabolism in Rat Testicular Cell Cultures." In Mechanisms and Models in Toxicology. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-72558-6_52.

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Bechter, R., R. Haebler, R. A. Ettlin, and R. L. Dixon. "Testicular Toxicity of Antineoplastic Drugs During Postnatal Development of the Rat." In Archives of Toxicology. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-69928-3_82.

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Foster, P. M. D. "m-Dinitrobenzene: Studies on its Toxicity to the Testicular Sertoli Cell." In Archives of Toxicology. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74117-3_1.

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Bobadilla, Maria, Laura Suter, and Rudolf Bechter. "Flow Cytometry as a Tool for the Evaluation of Testicular Toxicity." In Advances in Experimental Medicine and Biology. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4899-0089-0_9.

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"Testicular Toxicity." In Dictionary of Toxicology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9283-6_2647.

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Conference papers on the topic "Testicular toxicity"

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Levi, Mattan, Aaron Popovtzer, Moran Tzabari, Salomon M. Stemmer, Ruth Shalgi, and Irit Ben-Aharon. "Abstract 3840: Cetuximab-induced testicular toxicity." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3840.

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Alex, Aneesh, Jang Hyuk Lee, Jose J. Rico-Jimenez, Sunish Mohanan, Stephen A. Boppart, and Zane A. Arp. "Detecting testicular toxicity using label-free multimodal nonlinear optical imaging (Conference Presentation)." In Design and Quality for Biomedical Technologies XI, edited by Ramesh Raghavachari, Rongguang Liang, and T. Joshua Pfefer. SPIE, 2018. http://dx.doi.org/10.1117/12.2290646.

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Yildiz, Mustafa. "Effect of folic acid on testicular toxicity induced by bisphenol A in male Wistar rats." In 15th International Congress of Histochemistry and Cytochemistry. LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.op-13.

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Mustafa, Hesham N. "Ameliorative potentials of a combination of fenugreek and alpha-tocopherol on cadmium induced testicular toxicity: an ultrastructural study." In 15th International Congress of Histochemistry and Cytochemistry. LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.pp-165.

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Al-Mousaw, Mohammed, Ghadeer Sabah Bustani, Murtadha Jawad Al Barqaawee, and Yesar Mh AL-Shamma. "Evaluation of histology and sperm parameters of testes treated by lycopene against cyclophosphamide that induced testicular toxicity in Male rats." In 3RD INTERNATIONAL SCIENTIFIC CONFERENCE OF ALKAFEEL UNIVERSITY (ISCKU 2021). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0067059.

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Mohammad Hasan AL-MURSHIDI, Manar, Walaa Salih HASSAN, and Hala M.N. AL-SAILY. "AMELIORATIVE EFFECT OF BETA CAROTENE AGAINST TITANIUM DIOXIDE NANOPARTICLES REPRODUCTIVE TOXICITY ON TESTIS AND EPIDIDYMIS OF MALE ALBINO MICE MUS MUSCULUS." In IV.International Scientific Congress of Pure,Appliedand Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress4-20.

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The present study aimed to evaluate the improving or ameliorative effect of beta carotene on titanium dioxide nanoparticles induced testicular toxicity at the histological level. Forty adult healthy male albino mice weighting between 30-37gm and aged 12 to 15. Animals were randomly grouped in to four groups with ten mice in each: the first one was administered normal saline, whereas second group mice were administered 10 mg\kg body weight of beta carotene, third group were given 300 mg\kg body weight of titanium dioxide solution, last fourth group were administered 300 mg\kg body weight of tit
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Journal articles Dissertations / Theses
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