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Journal articles on the topic 'Testing mode administration'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Khoshsima, Hooshang, and Seyyed Morteza Hashemi Toroujeni. "Computer-Based Testing: Score Equivalence and Testing Administration Mode Preference in a Comparative Evaluation Study." International Journal of Emerging Technologies in Learning (iJET) 12, no. 10 (2017): 35. http://dx.doi.org/10.3991/ijet.v12i10.6875.

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The empirical evidences show that two identical Computer-Based Testing (henceforth CBT) and Paper-and-Pencil-Based Testing (henceforth PBT) do not always result in the same scores. Such conclusions are referred to as “the effect of testing administration mode” or “testing mode effect”. Moderators such as individual differences (e.g., prior computer experience or computer attitude) have been investigated [4] to see if they influence test takers’ performance. The Guidelines for Computer-Based Tests and Interpretations [1] recommended eliminating the possible effects of some moderator variables o

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Ebrahimi, Mohammad Reza, Seyyed Morteza Hashemi Toroujeni, and Vahide Shahbazi. "Score Equivalence, Gender Difference, and Testing Mode Preference in a Comparative Study between Computer- Based Testing and Paper-Based Testing." International Journal of Emerging Technologies in Learning (iJET) 14, no. 07 (2019): 128. http://dx.doi.org/10.3991/ijet.v14i07.10175.

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Abstract—Score equivalency of two Computer-Based Testing (henceforth CBT) and Paper-and-Pencil-Based Testing (henceforth PBT) versions has turned into a controversial issue during the last decade in Iran. The comparability of mean scores obtained from two CBT and PBT formats of test should be investigated to see if test takers’ testing performance is influenced by the effects of testing administration mode. This research was conducted to examine score equivalency across modes as well as the relationship of gender, and testing mode preference with test takers’ performance on computerized testin

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Russell, Michael, and Walt Haney. "Testing Writing on Computers." education policy analysis archives 5 (January 15, 1997): 3. http://dx.doi.org/10.14507/epaa.v5n3.1997.

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Computer use has grown rapidly during the past decade. Within the educational community, interest in authentic assessment has also increased. To enhance the authenticity of tests of writing, as well as of other knowledge and skills, some assessments require students to respond in written form via paper-and-pencil. However, as increasing numbers of students grow accustomed to writing on computers, these assessments may yield underestimates of students' writing abilities. This article presents the findings of a small study examining the effect that mode of administration -- computer versus paper

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Moe, Kim C., and Marilyn F. Johnson. "Participants' Reactions to Computerized Testing." Journal of Educational Computing Research 4, no. 1 (1988): 79–86. http://dx.doi.org/10.2190/qbqg-mrpx-hfd8-uvrp.

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This study investigated participants' reactions to computerized testing and assessed the practicability of this testing method in the classroom. Three hundred and fifteen students took a computerized and a printed version of a standardized aptitude test battery, and a survey assessing their reactions. Overall reactions to the computerized test were overwhelmingly positive. Students reported that computerized testing can be a workable alternative to printed standardized testing. Administrators' reactions were mixed; examiners were excited about this new mode of test administration but had some

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Khoshsima, Hooshang, Monirosadat Hosseini, and Seyyed Morteza Hashemi Toroujeni. "Cross-Mode Comparability of Computer-Based Testing (CBT) Versus Paper-Pencil Based Testing (PPT): An Investigation of Testing Administration Mode among Iranian Intermediate EFL Learners." English Language Teaching 10, no. 2 (2017): 23. http://dx.doi.org/10.5539/elt.v10n2p23.

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Advent of technology has caused growing interest in using computers to convert conventional paper and pencil-based testing (Henceforth PPT) into Computer-based testing (Henceforth CBT) in the field of education during last decades. This constant promulgation of computers to reshape the conventional tests into computerized format permeated the language assessment field in recent years. But, enjoying advantages of computers in language assessment raise the concerns of the effects that computerized mode of testing may have on CBT performance. Thus, this study investigated the score comparability

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Bartram, Dave, and Anna Brown. "Online Testing: Mode of Administration and the Stability of OPQ 32i Scores." International Journal of Selection and Assessment 12, no. 3 (2004): 278–84. http://dx.doi.org/10.1111/j.0965-075x.2004.282_1.x.

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Smith, Jason. "SHIFTING OF COGNITIVE ASSESSMENTS BETWEEN FACE-TO-FACE AND TELEPHONE ADMINISTRATION: MEASUREMENT CONSIDERATION." Innovation in Aging 8, Supplement_1 (2024): 415. https://doi.org/10.1093/geroni/igae098.1349.

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Abstract There is limited information concerning differences in cognitive performance attributable to assessment (telephone versus in-person) method instead of cognition. We evaluated mode effects on individual cognitive items and overall cognitive score in adults aged 65-79 in the 2014 Health and Retirement Study (n=6825). We assessed mode differences in test means and reliability, whether mode modifies associations of cognition with criterion variables, and formal measurement invariance testing by mode. People assessed by telephone tended to have higher scores for memory and calculation item

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Hooshang, Khoshsima, and Morteza Hashemi Toroujeni Seyyed. "TRANSITIONING TO AN ALTERNATIVE ASSESSMENT: COMPUTER-BASED TESTING AND KEY FACTORS RELATED TO TESTING MODE." European Journal of English Language Teaching 2, no. 1 (2017): 54–74. https://doi.org/10.5281/zenodo.268576.

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Computer-Based Testing (CBT) is becoming widespread due to its many identified positive merits including productive item development, flexible delivery testing mode, existence of self-selection options for test takers, immediate feedback, results management, standard setting and so on. Transitioning to CBT raised the concern over the effects of testing administration mode on test takers’ scores compared to Paper-and-Pencil-Based testing. In this comparability study, we compared the effects of two different media (CBT vs. PPT) by investigating the score comparability of General English test tak

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AKBAY, TUNCER. "Test Delivery Medium Matters: Cognitive Effort Exertion on Assessment." Malaysian Online Journal of Educational Technology 9, no. 2 (2021): 76–85. http://dx.doi.org/10.52380/mojet.2021.9.2.273.

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Integration of e-learning and computerized assessments into many levels of educational programs has been increasing as digital technology progresses. Due to a handful of prominent advantages of computer-based-testing (CBT), a rapid transition in test administration mode from paper-based-testing (PBT) to CBT has emerged. Recently, many national and international testing agencies have been offering an electronic version of some low- and high-stake tests along with their paper versions. In this study, we aim to examine test administration mode effect from a standpoint of cognitive effort exertion

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Smith, Jason, Laura Gibbons, Dan Mungas, et al. "ADAPTATION OF FACE-TO-FACE COGNITIVE ASSESSMENTS FOR TELEPHONE ADMINISTRATION: A POTENTIAL THREAT TO VALIDITY." Innovation in Aging 6, Supplement_1 (2022): 229–30. http://dx.doi.org/10.1093/geroni/igac059.912.

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Abstract Telephone-administered cognitive assessments are a cost-effective, feasible, and sometimes necessary alternative to in-person assessments. However, there is a scarcity of information in large cohort studies concerning mode effects, or differences in cognitive performance attributable to assessment method instead of underlying cognition, as a potential measurement threat. We evaluated mode effects on individual cognitive items and overall cognitive score using a population-based sample of community-living older adults aged 65-79 in the US in the 2014 Health and Retirement Study for who

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Hosseini, Monirosadat. "Replacing Paper-Based Testing with an Alternative for the Assessment of Iranian Undergraduate Students: Administration Mode Effect on Testing Performance." International Journal of Language and Linguistics 5, no. 3 (2017): 78. http://dx.doi.org/10.11648/j.ijll.20170503.13.

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Ong, Thai Q., Becky Krumm, Margaret Wells, et al. "A Comparison of Remote vs In-Person Proctored In-Training Examination Administration for Internal Medicine." Academic Medicine 99, no. 7 (2024): 778–83. http://dx.doi.org/10.1097/acm.0000000000005651.

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Abstract Purpose In response to COVID-19, the American College of Physicians provided residents the option to complete the 2020 Internal Medicine In-Training Examination (IM-ITE) via in-person and remote proctoring. This study evaluated the extent to which scores obtained from both testing modalities were comparable. Method Data were analyzed from residents from all U.S.-based Accreditation Council for Graduate Medical Education–accredited IM residency programs and participating Canadian and international programs who completed the IM-ITE in 2020. The final sample contained 27,115 IM residents

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Hol, A. Michiel, Harrie C. M. Vorst, and Gideon J. Mellenbergh. "Computerized Adaptive Testing for Polytomous Motivation Items: Administration Mode Effects and a Comparison With Short Forms." Applied Psychological Measurement 31, no. 5 (2007): 412–29. http://dx.doi.org/10.1177/0146621606297314.

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Mugford, Gerrard. "In search of one’s own evaluation criteria: The case of Mexican higher education." Verbum et Lingua, no. 3 (December 30, 2013): 36–48. http://dx.doi.org/10.32870/vel.vi3.25.

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n Mexico, the evaluation and assessment of teaching and learning of English as a foreign language is all too often undertaken by international examination boards. This paper examines the administration of language testing in the local context of Guadalajara, Mexico, and explores how testing could be developed to respond to local needs. By revisiting the concept of linguistic imperialism, I attempt to establish a framework for a mode of evaluation could be structured more closely to students’ needs and wants

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Alkhuseyn-Kulyaginova, Margarita S., Elizaveta M. Kotieva, Violetta M. Kotieva, Mohamad S. Abou Alou, Margarita A. Dodokhova, and Inga M. Kotieva. "Pathogenetic Aspects of Metronomic Administration of Compounds with an Alleged Antitumour Effect (Review)." Journal of Medical and Biological Research, no. 3 (September 1, 2023): 341–50. http://dx.doi.org/10.37482/2687-1491-z151.

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Chemotherapy is the main treatment method for malignant neoplasms. Classical administration regimens for chemotherapeutic agents are accompanied by strong side effects. Thus, there is a need for a rational mode of administration that can increase the effectiveness of chemotherapy and reduce its side effects. Development of new antitumour drugs must involve testing their pharmacological activity at various administration regimens. At the stage of preclinical studies of new compounds with an alleged antitumour effect, determining an optimal dosage regimen is an urgent task for interdisciplinary

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Bonifacci, Paola, Diego Compiani, Viola Ravaldini, Benedetta Peri, Alexandra Affranti, and Valentina Tobia. "A Multi-Informant Approach Testing an Expanded Home Numeracy Mode." Education Sciences 13, no. 3 (2023): 278. http://dx.doi.org/10.3390/educsci13030278.

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The role of home numeracy activities in the development of numeracy skills is receiving growing interest, although some mixed results highlight the need to consider models that include different contextual variables. The present study was aimed at investigating, using a multi-method and multi-informant approach, how parents’ educational levels, parents’ numerical attitudes, home numeracy, and expectations toward their offspring’s numeracy attitudes concurrently predict children’s early numeracy abilities as measured with early numeracy tasks and through teachers’ evaluations. The sample includ

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Mahajan, Rupali A. "A Future Online Analyzer for Hidden Project Management Risks." International Journal of Advanced Research in Computer Science and Software Engineering 7, no. 7 (2017): 99. http://dx.doi.org/10.23956/ijarcsse.v7i7.105.

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The aim of this qualitative study was to investigate and comprehend the conditions that impact software cost, requirement tracking as well as scheduled software testing as an online administration and inspire essential exploration issues. Interviews were led with administrators from five associations. Thestudy utilized qualitative grounded hypothesis as its exploration system. The effects show that the interest for software testing and online requirement monitoring as an online administration is on the ascent and is impacted by conditions, for example, the level of area information required to

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POTOSKY, DENISE. "PERSONNEL TESTING À LA MODE: A CONCEPTUAL FRAMEWORK FOR THE ROLE OF THE ADMINISTRATION MEDIUM IN THE ASSESSMENT PROCESS." Academy of Management Proceedings 2006, no. 1 (2006): L1—L6. http://dx.doi.org/10.5465/ambpp.2006.27162009.

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Narapong, Paweena, Thanomwan Prasertcharoensuk, Saowanee Sirisooksilp, and Keow Ngang Tang. "A Confirmatory Factor Analysis of Developing a High-Performance Primary School Model in the Northeast Region of Thailand." International Journal of Religion 5, no. 11 (2024): 1077–86. http://dx.doi.org/10.61707/74zy5c52.

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This study intended to explore the factors and indicators of high-performing administration for primary school in the northeast region of Thailand. The researchers employed a mixed-mode design. They conceptualized high-performing primary school administrative factors and indicators by analyzing documents and past studies, followed by a survey of 400 respondents with the purpose of testing the goodness of fit of the identified factors and indicators of high-performing primary school with the empirical data. The results discovered a total of 15 indicators resulting from the five factors in a hig

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Forkmann, T., H. Glaesmer, and L. Spangenberg. "“Mit Computern kenne ich mich eigentlich nicht aus …”." Nervenheilkunde 33, no. 09 (2014): 631–37. http://dx.doi.org/10.1055/s-0038-1627718.

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SummaryObjective: Self-report data is increasingly gathered by electronic devices. The present study aimed at testing usability and patient acceptance of two administration modes (tablet vs. paper-pencil) in primary care patients _ 60 years. Material and methods: Two depression instruments were administered using a randomized crossover design (n = 193). Results: Patients positively evaluated the usability of the tablet (clear presentation, well manageable). Additionally, the majority of patients preferred the tablet over the paper-pencil mode (more suitable, less stressful and difficult). Tabl

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Malec, Wojciech. "COMPUTER-BASED TESTING: A NECESSARY EVIL OR A SENSIBLE CHOICE?" Modern Higher Education Review, no. 5 (2020): 100–113. http://dx.doi.org/10.28925/2518-7635.2020.5.10.

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For many students and teachers working in online environments during the current pandemic crisis, the use of computers for educational testing is often an unavoidable predicament. This may be due to the fact that computer- based materials are not merely a useful addition to the learning and teaching resources, but rather the only option available. However, although in some contexts computers may indeed be a significant hindrance to test developers and test takers alike, they actually offer a number of substantial benefits. It is also worth pointing out that, by and large, educational tests del

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Covella, Bianca, Marica Giliberti, Adriano Montinaro, Luigi Rossi, and Vincenzo Montinaro. "Hereditary Angioedema: Novel Molecules for Treatment of Acute Attacks and Long-Term Prophylaxis." Future Pharmacology 4, no. 1 (2024): 41–53. http://dx.doi.org/10.3390/futurepharmacol4010005.

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Hereditary angioedema (HAE) is a rare disease caused by a genetic alteration of the SERPING1 gene and characterized by recurrent attacks of angioedema that involve the skin, and the mucosae of the gastrointestinal tract and upper airways, which significantly affect the quality of life of patients. Nowadays there are effective drugs for both 1. treating acute attacks and 2. preventing attacks with a long-term prophylaxis. However, there are some unmet needs for HAE treatment, and therefore several novel molecules are under active testing for this clinical condition. Novel drugs will simplify th

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Shalansky, Karen F., Eileen Y. H. Htan, Don M. Lyster, Brenda Mouat, and Martin G. Tweeddale. "In Vitro Evaluation of the Effect of Metered‐Dose Inhaler Administration Technique on Aerosolized Drug Delivery." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 13, no. 3 (1993): 233–38. http://dx.doi.org/10.1002/j.1875-9114.1993.tb02730.x.

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The administration of aerosolized metered‐dose inhalers (MDIs) to mechanically ventilated patients is labor intensive due to the large number of activations required and the currently recommended 30‐ to 60‐second “wait and shake” between each puff. No studies have been published that assess the relationship between this delay between puffs and drug delivery. To address this issue, we conducted an in vitro, randomized, single‐blind study using fenoterol MDI containing technetium‐99m pertechnetate. Four modes of MDI administration were tested in triplicate by random sequence. Eight activations o

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Yazan, Brahim. "Computer-Based Vs. Face-to-Face Speaking Assessment: Fitness for Purpose from a Communicative Language Testing View." International Journal of Social Science And Human Research 06, no. 01 (2023): 22–30. https://doi.org/10.5281/zenodo.7501172.

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Thanks to the ever-developing educational technologies, more and more educational institutions and testing organizations around the world have been delivering their testing events through computer-based formats. As far as language assessment is concerned, these developments have led to questions on all sorts of validity being raised by educational and assessment researchers, especially regarding the speaking skill. This exploratory paper compares and contrasts the pros and cons of computer- based and face-to-face assessment of speaking from a communicative view of language, by exploring what e

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Kolybanov, K. Yu, R. E. Kuzin, S. S. Pisanenko, and T. N. Tairov. "INFORMATION SYSTEM OF TESTING LABORATORY FOR RADIATION CONTROL." Fine Chemical Technologies 13, no. 4 (2018): 74–80. http://dx.doi.org/10.32362/2410-6593-2018-13-4-74-80.

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Development of information-analytical system of radiation control is based on existing methods and hardware-software measuring instruments for the purpose of systematizing, storing and processing the results of analysis of samples of various composition and origin. Studying a large flow of environmental and technological samples includes the most difficult task to ensure the required accuracy of calculation of activities and errors, especially at low activities levels at the threshold of detectable area. The information system hardware includes a set of devices designed to measure the activity

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Košak-Babuder, Milena, Judit Kormos, Michael Ratajczak, and Karmen Pižorn. "The effect of read-aloud assistance on the text comprehension of dyslexic and non-dyslexic English language learners." Language Testing 36, no. 1 (2018): 51–75. http://dx.doi.org/10.1177/0265532218756946.

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One of the special arrangements in testing contexts is to allow dyslexic students to listen to the text while they read. In our study, we investigated the effect of read-aloud assistance on young English learners’ language comprehension scores. We also examined whether students with dyslexia identification benefit from this assistance differently from their peers with no official identification of dyslexia. Our research was conducted with young Slovenian learners of English who performed four language assessment tasks adapted from a standardized battery of Slovenian national English language t

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Kang, Mary-Grace, Gabriella Isabel Tablante, Kristofferson Mendoza, et al. "CONTENT VALIDATION AND PILOT TESTING OF THE PROMOTING ACTIVE LIFESTYLE AMONG CHILDREN WITH DISABILITY (PALS) QUESTIONNAIRE." Philippine Journal of Physical Therapy 3, no. 1 (2024): 32. http://dx.doi.org/10.46409/002.nobg9032.

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Introduction: Primary carers and school teachers and administrators are key influencers in promoting active lifestyle among children with disabilities. The Promoting Active Lifestyle among Children with Disability (PALS) Questionnaire aims to determine these influencers' perceptions, capabilities, opportunities, and motivations in active healthy lifestyle promotion. This study evaluated the content validity and feasibility of the Filipino and English versions of the PALS Questionnaire. Methods: Six (6) experts rated the relevance of the items in the Filipino and English versions of the PALS Qu

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Kuhlmann, Sabine, Geert Bouckaert, Davide Galli, Renate Reiter, and Steven Van Hecke. "Opportunity management of the COVID-19 pandemic: testing the crisis from a global perspective." International Review of Administrative Sciences 87, no. 3 (2021): 497–517. http://dx.doi.org/10.1177/0020852321992102.

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This article provides a conceptual framework for the analysis of COVID-19 crisis governance in the first half of 2020 from a cross-country comparative perspective. It focuses on the issue of opportunity management, that is, how the crisis was used by relevant actors of distinctly different administrative cultures as a window of opportunity. We started from an overall interest in the factors that have influenced the national politics of crisis management to answer the question of whether and how political and administrative actors in various countries have used the crisis as an opportunity to f

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Chen, Kai, Hong Tan, Jie Gao, and Yang Lu. "Big Data Based Design of Food Safety Cloud Platform." Applied Mechanics and Materials 536-537 (April 2014): 583–87. http://dx.doi.org/10.4028/www.scientific.net/amm.536-537.583.

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Food safety has been in the spotlight of the global attention. In 2013, Chinas food safety supervision policy was undertaken a major reform. China Food and Drug Administration (CFDA) takes over the responsibility of food safety management, which in the past was conducted by different government sectors. Under this new management system, how to carry out the practical work has become a new issue. This paper introduces an innovative food safety management mode adopted by Guizhou province. On the basis of latest information technology, food production enterprises, government, testing organization

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Dvornikova, Olga, Vasily Samokhin, and Sergey Dvornikov. "Analyzing the first-year students’ motivation in choosing a technical university during the pandemic." Ergodesign, no. 1 (March 15, 2022): 45–50. http://dx.doi.org/10.30987/2658-4026-2022-1-45-50.

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The results of studying the motivational aspects of young people’s choice for admission to the Bonch-Bruevich Saint Petersburg State University of Telecommunications during the pandemic are presented based on processing the data from the first-year students’ annual testing. The characteristics of the respondents participating in the study are given. The areas covered by the research methodology are substantiated, and the stages of its implementation are disclosed, since testing was carried out in a delayed online mode. A detailed analysis of the results obtained is presented, some indicators o

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Levy, Robert M. "Quantitative, crossover, double-blind trial paradigm for patient screening for chronic intraspinal narcotic administration." Neurosurgical Focus 2, no. 1 (1997): E4. http://dx.doi.org/10.3171/foc.1997.2.1.5.

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Careful preoperative screening of candidates for indwelling drug administration systems for the relief of intractable pain can help to exclude patients who will not benefit from this technology and predict efficacy in others. Unfortunately, bias on the part of both the treating physician and the patient can inappropriately skew the results of subjective or improperly controlled trials and lead to the implantation of drug administration systems in patients who will not benefit from chronic intrathecal narcotic administration. The author and his coworkers have designed a quantitative, crossover,

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Sachs, Bonnie C., Stephen R. Rapp, Sarah A. Gaussoin, et al. "51 Feasibility of Remote Administration of a Modified UDSv3 Cognitive Battery." Journal of the International Neuropsychological Society 29, s1 (2023): 563–64. http://dx.doi.org/10.1017/s1355617723007221.

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Objective:Face-to-face administration is the “gold standard” for both research and clinical cognitive assessments. However, many factors may impede or prevent face-to-face assessments, including distance to clinic, limited mobility, eyesight, or transportation. The COVID19 pandemic further widened gaps in access to care and clinical research participation. Alternatives to face-to-face assessments may provide an opportunity to alleviate the burden caused by both the COVID-19 pandemic and longer standing social inequities. The objectives of this study were to develop and assess the feasibility o

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Peebles, Kathryn, Michael Witt, Jo-Anne Caton, et al. "Population-based estimates of COVID-19 period prevalence and cumulative monthly incidence in New York City: A comparison of estimates from three surveys, July–August 2020." Survey Practice 16, no. 1 (2023): 1–16. http://dx.doi.org/10.29115/sp-2023-0016.

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Background Diagnosis-based surveillance of COVID-19 underestimates COVID-19 burden. Questions about COVID-19-consistent symptoms were added to three population-based surveys to obtain representative estimates of COVID-19 period prevalence and monthly cumulative incidence. Objective To evaluate if estimates of COVID-19 period prevalence and cumulative monthly incidence differed when collected from surveys with different sampling frames and modes of administration. Methods Data were collected from adult New York City (NYC) residents via the Community Health Survey (CHS) (sampling frame: random d

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Aboyan, I. A., D. I. Pakus, S. M. Pakus, S. V. Grachev, and K. V. Berezin. "ROBOT-ASSISTED PELVIC LYMPH NODE DISSECTION USING ICG TESTING IN PATIENTS WITH PROSTATE CANCER." Cancer Urology 14, no. 3 (2018): 51–57. http://dx.doi.org/10.17650/1726-9776-2018-14-3-51-57.

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The objective is to investigate the possibility of using fluorescent testing in robot-assisted radical prostatectomy using indocyanine green (ICG testing) during pelvic lymph node dissection (PLND) in patients with localized prostate cancer.Materials and methods. Fifteen minutes prior to robot-assisted PLND, intraprostatic transperineal administration of 0.4 ml of indocyanine green (ICG) per lobe under transrectal ultrasound control was performed. Fluorescence map was used. After activation of the FireFly mode, fluorescence of the lymph nodes was evaluated. If a sentinel lymph node was present

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Ravazzi, Stefania. "Philanthropic Foundations and Local Policy Making in the Austerity Era: Does Urban Governance Matter?" Lex localis - Journal of Local Self-Government 14, no. 4 (2016): 917–35. http://dx.doi.org/10.4335/14.4.917-935(2016).

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Over the last decades, European cities have been facing serious constraints. In particular, decreasing transfers from central governments, the introduction of domestic ‘Stability pacts’ and the economic crisis have significantly challenged the capacity of local governments to address societal issues. Within this context, local governments have tried to find new ways by establishing collaborations with a wide range of private actors, including non-profit organizations and the civil society as a whole. Among these private actors, big philanthropic organizations are gaining prominence, acting as

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Coda, Barbara A., Mary Cleveland Brown, Linda BS Risler, Karen Syrjala, and Danny D. Shen. "Equivalent Analgesia and Side Effects during Epidural and Pharmacokinetically Tailored Intravenous Infusion with Matching Plasma Alfentanil Concentration." Anesthesiology 90, no. 1 (1999): 98–108. http://dx.doi.org/10.1097/00000542-199901000-00015.

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Background Recently, several clinical studies comparing intravenous and epidural infusions of fentanyl and its derivatives suggested that epidural infusions act primarily by systemic absorption to produce supraspinal analgesia. To evaluate this hypothesis, the authors used pharmacokinetically tailored intravenous infusions to produce matching plasma alfentanil concentrations during epidural and intravenous administration. The analgesia and side effects achieved with each mode of administration were compared. Methods Twelve volunteers participated in this placebo-controlled crossover study. The

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Parker, Samuel D., Michael R. Haberman, and Daniel R. Roettgen. "Time-varying elastic wave mode conversion in vibrating elastic beams with subwavelength nonlinearity." Journal of the Acoustical Society of America 152, no. 4 (2022): A294. http://dx.doi.org/10.1121/10.0016326.

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Introduction of time-varying properties in a background medium can enable unconventional wave behavior. Furthermore, it is well-known that subjecting nonlinear materials to time-varying stress can be used for material characterization [Appl. Phys. Lett. 94, 011905 (2009)]. We propose a technique called Dynamic Asymmetric Transmission Measurement (DATM) that combines structural dynamic (SD) and ultrasonic (US) testing modalities in an elastic waveguide to detect and characterize changes in the global stress state of a structure that result in local time-varying stress conditions due to local no

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Yairo, Akira, Ahmed S. Mandour, Katsuhiro Matsuura, et al. "Effect of Loading Changes on the Intraventricular Pressure Measured by Color M-Mode Echocardiography in Rats." Diagnostics 11, no. 8 (2021): 1403. http://dx.doi.org/10.3390/diagnostics11081403.

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Evaluation of diastolic function is a pivotal challenge due to limitations of the conventional echocardiography, especially when the heart rate is rapid as in rats. Currently, by using color M-mode echocardiography (CMME), intraventricular pressure difference (IVPD) and intraventricular pressure gradient (IVPG) in early diastole can be generated and are available as echocardiographic indices. These indices are expected to be useful for the early diagnosis of heart failure (HF), especially diastolic dysfunction. There have not been any studies demonstrating changes in IVPD and IVPG in response

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Chevalier, Joshua M., Karla Therese L. Sy, Sarah J. Girdwood, et al. "Optimal use of COVID-19 Ag-RDT screening at border crossings to prevent community transmission: A modeling analysis." PLOS Global Public Health 2, no. 5 (2022): e0000086. http://dx.doi.org/10.1371/journal.pgph.0000086.

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Countries around the world have implemented restrictions on mobility, especially cross-border travel to reduce or prevent SARS-CoV-2 community transmission. Rapid antigen testing (Ag-RDT), with on-site administration and rapid turnaround time may provide a valuable screening measure to ease cross-border travel while minimizing risk of local transmission. To maximize impact, we developed an optimal Ag-RDT screening algorithm for cross-border entry. Using a previously developed mathematical model, we determined the daily number of imported COVID-19 cases that would generate no more than a relati

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Zhang, Weiwei, Yan Wan, Shuding Sun, et al. "A Pharmacokinetic Study of Sixteen Major Bioactive Components of Jinshui-Huanxian Granules in Pulmonary Fibrosis Model and Control Rats Using Orbitrap Fusion Mass Spectrometry." Molecules 28, no. 18 (2023): 6492. http://dx.doi.org/10.3390/molecules28186492.

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Jinshui-Huanxian granules (JHGs), a Chinese herbal compound prescription, have shown a therapeutic effect in reducing lung tissue damage, improving the degree of pulmonary fibrosis, replenishing lungs and kidneys, relieving cough and asthma, reducing phlegm, and activating blood circulation. However, these active compounds’ pharmacokinetics and metabolic processes were unclear. This study aimed to compare the pharmacokinetics, reveal the metabolic dynamic changes, and obtain the basic pharmacokinetic parameters of 16 main bioactive compounds after intragastric administration of JHGs in control

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Zarrindast, M. R., M. Nasehi, and M. Pournaghshband. "Effects of dopaminergic drugs in the dorsal hippocampus of rats in the MK801-induced anxiolytic-like behavior." European Psychiatry 26, S2 (2011): 441. http://dx.doi.org/10.1016/s0924-9338(11)72148-4.

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IntroductionExcitatory transmission through glutamate receptors constitutes the main mode of synaptic signaling in the brain regions that are critical for cognition such as learning and anxiety.ObjectivesThe possible involvement of dorsal hippocampal (intra-CA1) dopaminergic receptor mechanism on the anxiolytic-like response induced by NMDA receptor antagonist, MK801 has been investigated in the present study.MethodsThe male wistar rats were used and the elevated plus maze apparatus has been used to test parameters (%OAT, %OAE, locomotor activity, grooming, rereading and defection) of anxiety-

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Vucetic-Arsic, S., M. Stankovic, S. Alcaz, and M. Nikic. "The transion of consumption patterns of heroin users in Belgrade." European Psychiatry 26, S2 (2011): 123. http://dx.doi.org/10.1016/s0924-9338(11)71834-x.

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ObjectiveDuring the last two decades illicit drug use in Belgrade has been changed.Previously, one of the most common methods of illicit heroin use was via intravenous injection. In 1987, injecting drug, as main consumption patterns was accepted by 90,6% of patients, although intravenous administration fell to 75,5% in 1995.The aim of the study was to observe if the main pattern of heroin consumption had changed lately.MethodsThe study included 382 illicit drug users (mean age 28,8 ± 4,7; both gender) treated in Special Hospital for Addiction, Belgrade in period of a year (Sept. 2009–2010).We

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Vosmerikov, Anton A., Andrey A. Stepanov, Ludmila N. Vosmerikova та Alexander V. Vosmerikov. "The effect of lanthanum additive on the physicochemical and catalytic properties of γ-Al2O3 in the process of propane conversion into olefin hydrocarbons". Vestnik Тomskogo gosudarstvennogo universiteta. Khimiya, № 35 (2024): 44–54. https://doi.org/10.17223/24135542/35/3.

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The effect of lanthanum concentration and introduction method on the physicochemical and catalytic properties of γ-Al2O3 in the process of propane conver-sion into olefin hydrocarbons was studied. It was found that modification of aluminum oxide with lanthanum by impregnation method resulted in decrease of the specific sur-face of the catalyst and increase of the pore size of the catalyst. Acid testing showed that the mode of administration and the concentration of lanthanum resulted in a change in the acid properties of the γ-Al2O3. It has been found that the addition of lanthanum to alumina

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Wolska, Eliza, Małgorzata Sznitowska, Juliusz Chorążewicz, et al. "Microscopic and Biopharmaceutical Evaluation of Emulsion and Self-Emulsifying Oil with Cyclosporine." Pharmaceuticals 16, no. 12 (2023): 1713. http://dx.doi.org/10.3390/ph16121713.

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Among the currently available commercial eye drops with cyclosporine A (Cs) there is a lack of long-acting dosage forms and products with a concentration of the drug substance higher than 0.1%, although Cs is widely used in ophthalmology. The aim of the research was to conduct the microscopic and biopharmaceutical evaluation of two formulations, an emulsion (EM) and a self-emulsifying oil (SEO), both with 0.5% of Cs, proposed for use in eye drops, and the comparison of both. SEO eye drops with Cs or any other drug substance are currently not available as marketed products, and the highest conc

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Fotiou, Aikaterini, Petros V. Vlastarakos, Angeliki-Eleni Sfetsiori, Evangelia-Filothei Tavoulari, Marianthi Liaska, and Iraklis Salvanos. "Respiratory problems in full term newborns, which parameters are related to the length of in-patient stay?" Česká gynekologie 88, no. 4 (2023): 264–72. http://dx.doi.org/10.48095/cccg2023264.

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Objective: To analyse respiratory problems of full term newborn babies during their first hours of life, compare parameters related to the length of neonatal intensive care unit (NICU) in-patient stay, and discuss perinatal care practices, which could prevent consequences, and/or reduce associated costs of NICU hospitalization. Material and methods: Retrospective chart review between July 31st 2017 and March 2nd 2018 in a tertiary maternity hospital. Chi-square testing analysed qualitative data. Mann-Whitney test was used for quantitative variables. Multiple linear regression models determined

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Dahlin, Jayme L., Michael J. Palte, John LaMacchia, and Athena K. Petrides. "A Rapid Dilute-and-Shoot UPLC-MS/MS Assay to Simultaneously Measure 37 Drugs and Related Metabolites in Human Urine for Use in Clinical Pain Management." Journal of Applied Laboratory Medicine 3, no. 6 (2019): 974–92. http://dx.doi.org/10.1373/jalm.2018.027342.

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Abstract Background Monitoring of medication compliance and drug abuse is used by clinicians to increase patient prescription drug compliance and reduce illicit drug abuse and diversion. Despite available immunoassays, chromatography-mass spectrometry–based methods are considered the gold standard for urine drug monitoring owing to higher sensitivities and specificities. Herein, we report a fast, convenient ultraperformance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS) assay to detect or quantify 37 clinically relevant prescription drugs, drugs of abuse, and related glucuronides

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Martin, Jeffrey S., Keiko Y. Gibson, and Lisa C. Huston. "Dichotic Listening Performance in Young Adults Using Low-Pass Filtered Speech." Journal of the American Academy of Audiology 23, no. 03 (2012): 192–205. http://dx.doi.org/10.3766/jaaa.23.3.6.

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Background: Assessment of interaural asymmetry (IA) on dichotic listening tests becomes challenging when accuracy on one or both ears are at ceiling. Cognitive task demands are often increased to avoid this situation, raising the possibility that non-auditory-specific processes will further influence IA estimation. Purpose: To investigate the utility of low-pass filtered dichotic speech stimuli (dichotic filtered words [DFWs]) as a potential auditory-specific technique for increasing task difficulty in the dichotic listening paradigm. Research Design: A prospective experimental study investiga

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Raghuvanshi, Ashish, Urooj A. Khan, Uzma Parveen, Anshul Gupta, and Gaurav K. Jain. "Development and Validation of UPLC-MS/MS Method for the Determination of Aripiprazole in Rat Plasma Using Liquid-Liquid Extraction: Pharmacokinetic and Bioequivalence Application." Asian Journal of Chemistry 32, no. 10 (2020): 2671–76. http://dx.doi.org/10.14233/ajchem.2020.22899.

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A selective, simple, sensitive and rapid ultra-performance liquid chromatographic tandem mass spectrometric (UPLC-MS/MS) method for the detection of aripiprazole in rat plasma has been developed and validated using aripiprazole-D8 as internal standard (IS). A simple single step sample preparation process was accomplished by liquid-liquid extraction (LLE). The post-treatment samples were chromato-graphed and analyzed on a UPLC bridged ethyl hybrid (BEH) C-18 column using mobile phase composition of acetonitrile: 0.1% formic acid in water::70:30 (v/v). Aripiprazole was analyzed by MS detector in

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ANDREEV, A. V., M. V. KRASNOV, and L. P. NIKITINA. "Compression stenosis of the abdominal trunk in the practice of a pediatrician." Practical medicine 20, no. 3 (2022): 111–16. http://dx.doi.org/10.32000/2072-1757-2022-3-111-116.

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The purpose — to analyze the Russian and foreign scientific literature on the features of compression stenosis of the abdominal trunk (CSAT) in the practice of a pediatrician, to conduct a clinical and laboratory examination of patients with chronic abdominal ischemia syndrome. Material and methods. This study included: group A (control) — 47 children without impaired blood flow in the abdominal trunk, group B (clinical) — 75 patients with chronic abdominal ischemia syndrome. The groups were comparable by the patients’ age and gender, which ensured the comparability of the data obtained. All c

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A., Venkatesh, and Manikandan R. "FUZZY MATHEMATICAL MODEL RELATIVE ANALYSIS FOR THE EFFECT OF OXYTOCIN IN PPH." International Journal of Interdisciplinary Research in Arts and Humanities 3, no. 1 (2018): 5–9. https://doi.org/10.5281/zenodo.1134403.

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In this study we discussed relative analysis for the various fuzzy mathematical models based on generalized gamma distribution, log-logistic distribution, generalized Rayleigh distribution and Rayleigh distribution for the effect of oxytocin.Testing of hypothesis between the expected values of cardiac output changes after the administration of oxytocinfor different distribution models.

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