Relevant bibliographies by topics / Testing of embryotoxicity

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters

Academic literature on the topic 'Testing of embryotoxicity'

Author: Grafiati
Published: 4 June 2021
Last updated: 8 February 2022

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Journal articles on the topic "Testing of embryotoxicity"

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Aikawa, Nobuo, Atsushi Kunisato, Kenji Nagao, Hideaki Kusaka, Katsumi Takaba, and Kinya Ohgami. "Detection of Thalidomide Embryotoxicity by In Vitro Embryotoxicity Testing Based on Human iPS Cells." Journal of Pharmacological Sciences 124, no. 2 (2014): 201–7. http://dx.doi.org/10.1254/jphs.13162fp.

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Delaroche, L., P. Oger, E. Genauzeau, et al. "Embryotoxicity testing of IVF disposables: how do manufacturers test?" Human Reproduction 35, no. 2 (2020): 283–92. http://dx.doi.org/10.1093/humrep/dez277.

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Abstract STUDY QUESTION How do manufacturers perform embryotoxicity testing in their quality control programs when validating IVF consumables? SUMMARY ANSWER The Mouse Embryo Assay (MEA) and Human Sperm Survival Assay (HSSA) used for IVF disposables differed from one manufacturer to another. WHAT IS KNOWN ALREADY Many components used in IVF laboratories, such as culture media and disposable consumables, may negatively impact human embryonic development. STUDY DESIGN, SIZE, DURATION Through a questionnaire-based survey, the main manufacturers of IVF disposable devices were contacted during the
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Romero, Andrea C., Eugenio Vilanova, and Miguel A. Sogorb. "Shortening and Improving the Embryonic Stem Cell Test through the Use of Gene Biomarkers of Differentiation." Journal of Toxicology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/286034.

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The embryonic Stem cell Test (EST) is a validated assay for testing embryotoxicityin vitro. The total duration of this protocol is 10 days, and its main end-point is based on histological determinations. It is suggested that improvements on EST must be focused toward molecular end-points and, if possible, to reduce the total assay duration. Five days of exposure of D3 cells in monolayers under spontaneous differentiation to 50 ng/mL of the strong embryotoxic 5-fluorouracil or to 75 μg/mL of the weak embryotoxic 5,5-diphenylhydeantoin caused between 20 and 74% of reductions in the expression of
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Boos, Julia Alicia, Patrick Mark Misun, Astrid Michlmayr, Andreas Hierlemann, and Olivier Frey. "Microfluidic Multitissue Platform for Advanced Embryotoxicity Testing In Vitro." Advanced Science 6, no. 13 (2019): 1900294. http://dx.doi.org/10.1002/advs.201900294.

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Aikawa, N. "The development of in vitro embryotoxicity testing using human iPS cells." Toxicology Letters 295 (October 2018): S70. http://dx.doi.org/10.1016/j.toxlet.2018.06.521.

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Giavini, Erminio, Maria Luisa Broccia, and Mariangela Prati. "Teratogenicity Testing In Vitro: Post-implantation Whole-embryo Culture." Alternatives to Laboratory Animals 19, no. 1 (1991): 94–98. http://dx.doi.org/10.1177/026119299101900118.

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Various in vitro models have recently been tested for the assessment of developmental toxicity. Since the mechanisms involved in chemically-induced embryotoxicity are complex and numerous, a good in vitro assay must be able to detect developmental toxicants which act via most or all of these mechanisms. The rodent whole-embryo culture seems to fit this requirement, because it undergoes all of the fundamental processes of development. Also physical relationships between cells and tissues are maintained and morphogenesis can proceed normally. In fact, in vitro development of early post-implantat
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Bremer, Susanne, Cristian Pellizzer, Sarah Adler, Martin Paparella, and Jan de Lange. "Development of a Testing Strategy for Detecting Embryotoxic Hazards of Chemicals In Vitro by using Embryonic Stem Cell Models." Alternatives to Laboratory Animals 30, no. 2_suppl (2002): 107–9. http://dx.doi.org/10.1177/026119290203002s16.

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The importance of developing in vitro tests for embryotoxicity is discussed, and ECVAM's work with its collaborators is summarised. Studies are in progress to find new endpoints for use in the scientifically validated embryonic stem (ES) cell test, so that the potential for chemical effects on endodermal, mesodermal and/or ectodermal differentiation can be identified. This involves, inter alia, the use of genetically modified ES cells.
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Prelusky, Dan B., Robert M. G. Hamilton, Brian C. Foster, Locksley H. Trenholm, and Brian K. Thompson. "Optimization of Chick Embryotoxicity Bioassay for Testing Toxicity Potential of Fungal Metabolites." Journal of AOAC INTERNATIONAL 70, no. 6 (1987): 1049–55. http://dx.doi.org/10.1093/jaoac/70.6.1049.

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Abstract The optimization of a simple, sensitive procedure using a chick embryotoxicity screening test (CHEST) bioassay for detection of toxic compounds is presented. Dosing protocols of eggs, using several mycotoxins (aflatoxin B„ deoxynivalenol, T-2 toxin) and appropriate controls, were evaluated for embryonic sensitivity, overall practicality of the procedure, and consistency of results. It was found that both type of carrier solvent and volume injected could significantly affect overall embryonic mortality. The chick embryo was most sensitive to the effects of toxins and solvents after 1 o
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Babić, Sanja, Josip Barišić, Draženka Stipaničev, et al. "Assessment of river sediment toxicity: Combining empirical zebrafish embryotoxicity testing with in silico toxicity characterization." Science of The Total Environment 643 (December 2018): 435–50. http://dx.doi.org/10.1016/j.scitotenv.2018.06.124.

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Schrattenholz, Andre. "Proteomic surrogate biomarkers for in vitro testing of embryotoxicity: Quantitative differential investigation of ESC models." Toxicology Letters 189 (September 2009): S31. http://dx.doi.org/10.1016/j.toxlet.2009.06.058.

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Dissertations / Theses on the topic "Testing of embryotoxicity"

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Emelogu, Emmanuel Steven. "Combined effects of bioavailable organic contaminants in the aquatic environment." Thesis, Robert Gordon University, 2013. http://hdl.handle.net/10059/840.

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Passive sampling, as opposed to the conventional spot or bottle water sampling technique, has shown to be reliable and efficient in monitoring the toxicologically relevant, freely dissolved (e.g. bioavaialable) concentrations of a wide range of organic contaminants in water. At the same time, partitioning controlled delivery (passive dosing; PD) techniques promise to overcome many of the challenges associated with toxicity testing of hydrophobic substances that may bias the interpretation of toxicity data. The present study investigated the feasibility of coupling silicone rubber passive sampl
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Pavlíková, Zuzana. "Testování embryotoxicity vybraných lidských teratogenů na zárodcích kuřete." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-312523.

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Teratogenes are external environmental factors that can cause a developmental or a congenital defect in exposed individuals. The methods used for detecting the embryotoxic effect of substances are the classic when laboratory mammals are used and the alternative which use in vitro and in ovo systems. The main difference between these two is that the alternative methods lack metabolism of maternal organism. The metabolism of maternal organism brings a high variability of results to systems of the classic methods. We used two alternative methods in this thesis, both using chicken embryo. The firs
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Books on the topic "Testing of embryotoxicity"

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Joint American-Swiss Seminar on Alternative Embryotoxicity and Teratogenicity Tests (1984 Zurich, Switzerland). In vitro embryotoxicity and teratogenicity tests: Joint American-Swiss Seminar on Alternative Embryotoxicity and Teratogenicity Tests, Zürich, November 12, 1984. Edited by Homburger Freddy and Goldberg Alan M. New York, 1985.

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Book chapters on the topic "Testing of embryotoxicity"

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Davies, Wendy J., and Stuart J. Freeman. "Chick Embryotoxicity Screening Test (CHEST I and II)." In In Vitro Toxicity Testing Protocols. Humana Press, 1995. http://dx.doi.org/10.1385/0-89603-282-5:307.

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Popov, Vadim, and Galina Protasova. "In vitro embryotoxicity testing." In Reproductive and Developmental Toxicology. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-382032-7.10012-8.

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You might also be interested in the extended bibliographies on the topic 'Testing of embryotoxicity' for particular source types:
Journal articles
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