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Relevant bibliographies by topics / Testis determination

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Academic literature on the topic 'Testis determination'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Testis determination"

1

KOBAYASHI, A. "Sox9 in Testis Determination." Annals of the New York Academy of Sciences 1061, no. 1 (2005): 9–17. http://dx.doi.org/10.1196/annals.1336.003.

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Turner, Monte E., Daniel Ely, Jeremy Prokop, and Amy Milsted. "Sry, more than testis determination?" American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 301, no. 3 (2011): R561—R571. http://dx.doi.org/10.1152/ajpregu.00645.2010.

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The Sry locus on the mammalian Y chromosome is the developmental switch responsible for testis determination. Inconsistent with this important function, the Sry locus is transcribed in adult males at times and in tissues not involved with testis determination. Sry is expressed in multiple tissues of the peripheral and central nervous system. Sry is derived from Sox3 and is similar to other SOXB family loci. The SOXB loci are responsible for nervous system development. Sry has been demonstrated to modulate the catecholamine pathway, so it should have functional consequences in the central and peripheral nervous system. The nervous system expression and potential function are consistent with Sry as a SOXB family member. In mammals, Sox3 is X-linked and undergoes dosage compensation in females. The expression of Sry in adult males allows for a type of sexual differentiation independent of circulating gonadal hormones. A quantitative difference in Sox3 plus Sry expression in males vs. females could drive changes in the transcriptome of these cells, differentiating male and female cells. Sry expression and its transcriptional effects should be considered when investigating sexual dimorphic phenotypes.

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Carrillo, Adriana Alejandra, and Gary David Berkovitz. "Genetic Mechanisms that Regulate Testis Determination." Reviews in Endocrine and Metabolic Disorders 5, no. 1 (2004): 77–82. http://dx.doi.org/10.1023/b:remd.0000016126.57801.c0.

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Meeks, Joshua J., Jeffrey Weiss, and J. Larry Jameson. "Dax1 is required for testis determination." Nature Genetics 34, no. 1 (2003): 32–33. http://dx.doi.org/10.1038/ng1141.

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Lovell-Badge, Robin. "Testis determination: soft talk and kinky sex." Current Opinion in Genetics & Development 2, no. 4 (1992): 596–601. http://dx.doi.org/10.1016/s0959-437x(05)80178-9.

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LOVELLBADGE, R. "Testis determination: soft talk and kinky sex." Current Biology 2, no. 9 (1992): 486. http://dx.doi.org/10.1016/0960-9822(92)90670-6.

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Clement, Tracy M., Matthew D. Anway, Mehmet Uzumcu, and Michael K. Skinner. "Regulation of the gonadal transcriptome during sex determination and testis morphogenesis: comparative candidate genes." Reproduction 134, no. 3 (2007): 455–72. http://dx.doi.org/10.1530/rep-06-0341.

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Gene expression profiles during sex determination and gonadal differentiation were investigated to identify new potential regulatory factors. Embryonic day 13 (E13), E14, and E16 rat testes and ovaries were used for microarray analysis, as well as E13 testis organ cultures that undergo testis morphogenesis and develop seminiferous cordsin vitro. A list of 109 genes resulted from a selective analysis for genes present in male gonadal development and with a 1.5-fold change in expression between E13 and E16. Characterization of these 109 genes potentially important for testis development revealed that cytoskeletal-associated proteins, extracellular matrix factors, and signaling factors were highly represented. Throughout the developmental period (E13–E16), sex-enriched transcripts were more prevalent in the male with 34 of the 109 genes having testis-enriched expression during sex determination. In ovaries, the total number of transcripts with a 1.5-fold change in expression between E13 and E16 was similar to the testis, but none of those genes were both ovary enriched and regulated during the developmental period. Genes conserved in sex determination were identified by comparing changing transcripts in the rat analysis herein, to transcripts altered in previously published mouse studies of gonadal sex determination. A comparison of changing mouse and rat transcripts identified 43 genes with species conservation in sex determination and testis development. Profiles of gene expression during E13–E16 rat testis and ovary development are presented and candidate genes for involvement in sex determination and testis differentiation are identified. Analysis of cellular pathways did not reveal any specific pathways involving multiple candidate genes. However, the genes and gene network identified influence numerous cellular processes with cellular differentiation, proliferation, focal contact, RNA localization, and development being predominant.

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Graves, Jennifer A. Marshall. "From brain determination to testis determination: evolution of the mammalian sex-determining gene." Reproduction, Fertility and Development 13, no. 8 (2001): 665. http://dx.doi.org/10.1071/rd01093.

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In mammals, sex is determined by an XY male:XX female sex chromosome system in which a male-dominant gene on the Y chromosome (SRY) determines testis formation. Sex chromosomes evolved from an ordinary autosome pair as the Y chromosome was progressively degraded. The Y chromosome has lost nearly all of its 1500 original genes, and those that survived did so because they evolved a critical role in male determination or differentiation. SRY is typical of Y-borne genes. Comparative gene mapping and sequencing shows that SRY arose quite recently as a degraded version of the SOX3 gene on the X chromosome. SOX3 is expressed predominantly in brain, and so is more likely to be a brain-determining than a testis-determining gene. The male-dominant action of SRY may be an illusion, as its structure suggests that it works by interfering with the action of a related gene, which in turn inhibits testis development. This hypothesis can give a good account of how a brain-determining gene acquired a role in testis determination via differential dosage of SOX3. SRY has no central role in sex determination and it can be replaced as a trigger and lost, as have many other Y-borne genes in recent evolutionary history. The absence of SRY in two species of the mole vole (Ellobius) suggests that its useful life is already running out.

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Veitia, Reiner A., Laura Salas-Cortés, Chris Ottolenghi, Eric Pailhoux, Corinne Cotinot, and Marc Fellous. "Testis determination in mammals: more questions than answers." Molecular and Cellular Endocrinology 179, no. 1-2 (2001): 3–16. http://dx.doi.org/10.1016/s0303-7207(01)00460-9.

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Sekido, Ryohei. "SRY: A transcriptional activator of mammalian testis determination." International Journal of Biochemistry & Cell Biology 42, no. 3 (2010): 417–20. http://dx.doi.org/10.1016/j.biocel.2009.12.005.

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Dissertations / Theses on the topic "Testis determination"

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May, Joel. "Gadd45g and mammalian testis determination." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:6ce4cf97-83da-4cc6-a433-25947f53a7f3.

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Mammalian sex is determined by the presence or absence of Sry. This gene, located on the Y chromosome, promotes the development of a testis from the biopotential gonad by initiating a transcriptional programme that results in Sertoli cell formation. SRY is required to reach a specific threshold level during a critical time-period in order to induce the testicular differentiation pathway. We have previously shown that XY mouse embryos lacking Growth arrest and DNA damage inducible 45 gamma (Gadd45g) exhibit gonadal sex reversal due to a delay in Sry expression. Efforts to study the role of GADD45γ in sex determination have been stymied by the lack of a working antibody. As an alternative, I have produced a BAC transgene produces a similar expression profile to endogenous Gadd45g. This BAC was also shown to rescue the sex reversal found in B6-Y<sup>POS</sup> gonads, though further research is required to understand the molecular mechanisms through which this occurs. As a result, this BAC was chosen for modification using BAC recombineering to contain the sequence for a poly-His/FLAG epitope tag. Though this edited BAC was generated successfully, no transgenic lines have yet been produced. Members of the Gadd45 family have previously been associated with active DNA demethylation. Assuch, I have conducted whole genome bisulphite sequencing on DNA from XY wild-type, XX wild-type and XY Gadd45g<sup>-/-</sup> embryos at the 18 tail somite stage, where Sry expression is at its peak. Gadd45g and Sry are only expressed in the somatic cells of the gonads, which have been purified through fluorescence-activated flow cytometry using the transgenic line Sf1-EGFP. Due to the low number of cells that are purified from the embryonic gonad at this stage, sequencing libraries were generated using post-bisulphite adaptor tagging (PBAT). Analysis of the acquired sequences revealed that there are no significant differences between the methylomes of XY wild-type, XX wild-type and XY Gadd45g<sup>-/-</sup> mutant gonadal somatic cells. It therefore appears that GADD45γ does not have a role in establishing the methylome at this particular stage of sex determination.

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Clement, Tracy M. "Molecular mechanisms of sex determination and testis differentiation." Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Dissertations/Spring2009/t_clement_050709.pdf.

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Hacker, Adam Michael. "Gene expression during testis determination in the mouse." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283285.

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Gordon, Kerry. "Determination of the glycosylation requirements for active human testis angiotensin-converting enzyme." Master's thesis, University of Cape Town, 2002. http://hdl.handle.net/11427/3392.

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Collignon, Jerome Vincent. "Study of a new family of genes relating to the mammalian testis determining gene." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316658.

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Pope, Madeleine Jane. "Loss- and gain-of-function analyses of the role of MAP kinase signalling in testis determination." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:b02ff1d1-2b16-44f7-8008-7cd7867d1536.

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Sexual differentiation is the process by which an organism develops as either male or female. In mammals, this process is governed chromosomally, principally by the presence or absence of the Y chromosome. In the mouse, sex determination occurs at 11.5 days post coitum (dpc), when expression of Sry in the XY gonad kick-starts testis determination. SRY drives the subsequent expression of genes that both promote testis differentiation and inhibit ovarian differentiation, leading to specification of the testis. In cases where sex determination is disrupted, disorders of sexual development (DSD) can occur. Many genes have been described that are required for testis determination. However, we still know relatively little about how Sry itself is regulated. MAP kinase (MAPK) signalling is involved in testis determination in mice and humans. MAP3K4 is required for testis determination in the mouse: loss of MAP3K4 is associated with male-to-female sex reversal in embryos and insufficient expression of Sry at 11.5 dpc. Likewise, loss of function of a protein known to interact with MAP3K4, GADD45?, also leads to sex reversal. In humans, mutations in the gene encoding the related kinase, MAP3K1, have been identified as a key cause of DSD. Thus, MAPK signalling appears to play a key role in testis determination both in humans and mice. This thesis describes experiments designed to further elucidate the role of MAPK-related signalling in testis determination. Firstly, an attempt was made to generate mice bearing a human sex-reversing mutation in Map3k1, however this was not successful. Additionally, RNA-seq was employed to investigate transcriptional targets of GADD45?. Finally, the role of MAP3K4 as a dose-dependent modifier of sensitivity to sex reversal in mice is described, utilising a Map3k4 transgene to rescue sex reversal in B6 mice harbouring a Y chromosome from the Mus poschiavinus strain. These mice undergo sex reversal in the absence of the Map3k4 transgene, and also exhibit delayed Sry expression. By utilising this genetic tool, this thesis investigates the mechanism of sex reversal in these mice, with particular focus on the role pf Map3k4 in Sry expression.

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Chen, Yen-Shan. "MAMMALIAN TESTIS-DETERMINING FACTOR SRY HAS EVOLVED TO THE EDGE OF AMBIGUITY." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1372888881.

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Wobser, Madison June. "Determination of the Structure of Human Testis Protein Maelstrom and Examination of Functional Differences among Human Genome Variants." Walsh University Honors Theses / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=walshhonors1555605939425746.

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Brixey, Rachel J. E. "Genetic analyses of MAP kinase signalling in mouse gonad development." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:54242de2-8e43-4cf2-ad12-d94a2c187c44.

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Sexual development begins with the process by which the bipotential gonads of the embryonic urogenital ridge develop into either testes or ovaries. In the mouse, sex determination occurs at around 11.5 dpc and depends on the presence or absence of the Y chromosome and the associated activity of the testis-determining gene, Sry, in supporting cell precursors. The mutually antagonistic male and female developmental pathways are regulated by many cellular and molecular processes, disruption of which can lead to disorders of sex development (DSDs). However, many of the molecular mechanisms regulating the differentiation of the two gonads are still unknown. The boygirl (byg) mutant was identified in an ENU-based forward genetic screen for embryos with gonadal abnormalities. On the C57BL/6J background, XY byg/byg homozygotes exhibited complete embryonic gonadal sex reversal. The defective gene in byg, Map3k4, is a component of the mitogen-activated protein (MAP) kinase signalling pathway and provides the first evidence for a function of this pathway in sex determination. This thesis describes experiments aimed at investigating the cellular and molecular basis of the sex reversal phenotype associated with the XY Map3k<sup>4byg/byg</sup> mutant. Cellular characterisations revealed a defect in male-specific proliferation at 11.5 dpc, which was attributed to a defect in Sry up-regulation. Elucidation of the downstream kinases activated by MAP3K4 during sex determination was attempted, with particular focus on identifying a role for p38α MAP kinase (MAPK). Using a conditional knockout approach, the function of p38α in Steroidogenic factor-1 (Sf1)-positive somatic cells was assessed. However, specific inactivation in these cells did not affect gonad development. Conditional inactivation of Map3k4 itself in these Sf1¬-positive cells also did not disrupt gonad development, suggesting that this pathway is either initiated in a different cell lineage or at an earlier stage than deletion driven by Sf1-Cre can disrupt. Conditional inactivation of p38α in the Müllerian duct mesenchyme and ovarian granulosa cells using Amhr2-Cre did reveal a function for p38α in female fertility, but did not disrupt embryonic sexual development. Gene knockdown in organ culture was attempted to determine a role for multiple p38 MAPKs in all cell types of the gonad. Therefore, this thesis details further characterisations of a novel signalling pathway important for the expression of Sry, focussing on the role of the p38 MAPKs.

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Tomaszkiewicz, Marta. "Molecular characterization of the Y chromosome-linked sex-determining region of the platyfish Xiphophorus maculatus." Thesis, Lyon, École normale supérieure, 2012. http://www.theses.fr/2012ENSL0791.

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De par leur diversité de mécanismes de déterminisme du sexe et de chromosomes sexuels, les poissons téléostéens représentent d’excellents modèles pour mieux comprendre les bases moléculaires et évolutives du contrôle du développement sexuel chez les vertébrés. Grâce à l’analyse de chromosomes artificiels bactériens couvrant les chromosomes sexuels du platy Xiphophorus maculatus, trois copies d’un nouveau gène nommé teximY ont été découvertes dans la région de déterminisme du sexe du chromosome Y mais pas du chromosome X. Un gène texim1 très apparenté à teximY ainsi que trois gènes plus divergents ont été identifiés sur les autosomes. Les gènes teximY sont préférentiellement exprimés dans les testicules, au niveau des cellules germinales lors des étapes tardives de la spermatogénèse, alors que texim1 est également transcrit dans les gonades femelles. Des gènes texim ont été détectés chez d'autres poissons téléostéens mais pas chez le poisson-zèbre, ainsi que chez des céphalocordés, des urocordés et des échinodermes mais pas chez les tétrapodes. Les gènes texim codent pour des estérases putatives à domaine SGNH apparentées à des protéines cellulaires procaryotes et eucaryotes ou codées par des retrotransposons animaux. Les gènes texim sont associés à des transposons Helitron chez les poissons mais pas chez les autres animaux, suggérant capture et mobilisation du gène ancestral texim par un transposon à la base de la radiation des téléostéens. TeximY pourrait jouer un rôle dans la transposition du transposon Helitron dans la lignée germinale mâle, ou correspondre à un gène de spermatogenèse mobilisé par le transposon Helitron sur les nouveaux chromosomes sexuels de poissons<br>The molecular and evolutionary basis of sex determination in vertebrates needs to be unveiled via comparison of different systems. Fish exhibit hypervariability of sex determination mechanisms. Thanks to the analysis of the Bacterial Artificial Chromosome (BAC) library covering the sex chromosomes of the platyfish Xiphophorus maculatus (Rio Jamapa population, XX /XY), three copies of a new gene have been identified in the sex-determining region of the Y but not the X chromosome, and named teximY. Four autosomal counterparts of teximY have been also detected in the genome of the platyfish with one of them, texim1 presenting 95% of cDNA sequence identity with the Y-linked copies. RT-qPCR expression analyses have been performed for each copy in male and female tissues. Two Y-linked teximY copies were preferentially expressed in testis, whereas the autosomal copy texim1 showed preferential expression in male and female gonads. In situ hybridizations with a teximY/1 probe revealed expression in late spermatids and spermatozeugmata. Texim sequences were detected in several fish species, but not in zebrafish, as well as in cephalochordates, urochordates and sea echinoderms but not in tetrapods. Predicted Texim proteins are related to proteins from different origins. Interestingly, texim genes are associated with a Helitron transposon in fish but neither in cephalochordates nor in echinoderms, suggesting capture and mobilization of an ancestral texim gene at the base of the bony fish lineage. TeximY proteins may play a role in Helitron transposition in the male germ line in fish, or texim genes are spermatogenesis genes mobilized and spread by transposable elements in fish genomes

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Books on the topic "Testis determination"

1

Connecticut. General Assembly. Legislative Program Review and Investigations Committee. Medicaid eligibility determination process. Connecticut General Assembly, Legislative Program Review and Investigations Committee, 2004.

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2

Link, Carol L. Statistical determination of preservative threshold retention in soil block tests. Forest Products, 1988.

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Institution, British Standards. Plastics: Determination of temperature of deflection under load. BSI, 1994.

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Friedel, Michael. Stress determination in rock using the Kaiser effect. Bureau of Mines, U.S. Dept. of the Interior, 1990.

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Friedel, Michael. Stress determination in rock using the Kaiser effect. Dept. of the Interior, 1989.

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James, C. C. Determination of fat in milk. Dept. of Agriculture, 1993.

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Naik, Rajiv A. Determination of fiber-matrix interface failure parameters from off-axis tests. National Aeronautics and Space Administration, Langley Research Center, 1993.

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Naik, Rajiv A. Determination of fiber-matrix interface failure parameters from off-axis tests. National Aeronautics and Space Administration, Langley Research Center, 1993.

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Naik, Rajiv A. Determination of fiber-matrix interface failure parameters from off-axis tests. National Aeronautics and Space Administration, Langley Research Center, 1993.

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Naik, Rajiv A. Determination of fiber-matrix interface failure parameters from off-axis tests. National Aeronautics and Space Administration, Langley Research Center, 1993.

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Book chapters on the topic "Testis determination"

1

Singh, Neha, and Deepak Modi. "The Molecular Genetics of Testis Determination." In Genetics of Male Infertility. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-37972-8_1.

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de la Chapelle, A. "The genetic basis of testis determination in man." In Chromosomes Today. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9166-4_15.

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Harley, Vincent R. "The Molecular Action of Testis-Determining Factors SRY and SOX9." In The Genetics and Biology of Sex Determination. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/0470868732.ch6.

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T�h�nen, V., E. M. Ritz�n, K. Nordqvist, and A. Wedell. "Male Sex Determination and Prenatal Differentiation of the Testis." In Endocrine Development. KARGER, 2003. http://dx.doi.org/10.1159/000069299.

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Smith, Craig A., and Andrew H. Sinclair. "The Cell Biology and Molecular Genetics of Testis Determination." In Results and Problems in Cell Differentiation. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-540-48461-5_2.

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Graves, Jennifer A. Marshall. "Evolution of the Testis-Determining Gene-The Rise and Fall of SRY." In The Genetics and Biology of Sex Determination. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/0470868732.ch9.

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Koopman, Peter, Monica Bullejos, Kelly Loffler, and Josephine Bowles. "Expression-Based Strategies for Discovery of Genes Involved in Testis and Ovary Development." In The Genetics and Biology of Sex Determination. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/0470868732.ch19.

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Bell, Michael J., Michael L. Thompson, and Philip W. Moody. "Using Soil Tests to Evaluate Plant Availability of Potassium in Soils." In Improving Potassium Recommendations for Agricultural Crops. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59197-7_8.

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AbstractThe purpose of this chapter is to describe how bioavailable soil K is assessed or predicted by soil tests. Soil testing commonly refers to the collection of a sample of soil representative of a field or agronomic management unit and, by way of extraction using chemical reagents, determination of the quantity of a nutrient that can be related to plant uptake or yield. Normally only a small fraction of the total quantity of the nutrient present in the soil is extracted during the procedure, but if that amount can be correlated with actual crop uptake or overall crop productivity, then the soil test is deemed to have useful predictive power.Soil tests are routinely used to guide applications of fertilizer to soil so that crop demand for nutrients can be met effectively and economically. Here, we summarize the procedures involved in collecting a representative soil sample for K analysis, outline how that sample should be prepared for laboratory analysis, highlight the principles and mode of action of routine soil tests, and explore some common issues that may confound the correlation between a soil K test result and plant K acquisition or crop yield. Soil testing methods are discussed in the context of their relationship to the different forms of soil K and the in-soil chemical processes that may change these forms into K that can be taken up by roots.

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Koldovsky, P., and U. Koldovsky. "Tests for Determination of Lymphocyte Activity." In Lymphocytes in Immunotherapy of Cancer. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74225-5_5.

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de Jong, Eelke. "Exchange Rate Determination: Theory and Empirical Tests." In Lecture Notes in Economics and Mathematical Systems. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-51668-9_2.

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Conference papers on the topic "Testis determination"

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Stratil, Ludek, Filip Siska, Ivo Dlouhy, and Marta Serrano. "The Application of Miniaturized Three-Point-Bend Specimens for Determination of the Reference Temperature of JRQ Steel." In ASME 2015 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/pvp2015-45706.

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This contribution deals with determination of the reference temperature of JRQ steel using miniaturized specimens. The dimensions of used miniaturized specimens were 3 × 4 × 27 mm (thickness × width × length). This specimen type offers the utilization of limited amount of test material or broken halves of precracked Charpy and larger specimens. The test material comes from the broken halves of 0.5T SEB specimens previously tested for purposes of the reference temperature determination in Ciemat, Madrid. The fracture toughness tests of specimens were performed in the transition region of the steel according to the recommendations of standard ASTM E1921 and according Wallin’s recommended temperature range for miniaturized specimens. The determined reference temperature of the Master Curve was very similar to the determined ones from three-point-bend specimen of sizes 0.2T, 0.4T and 0.5T. The obtained results confirm a necessity of conduct of tests at low temperatures and testing sufficient number of specimens in order to generate enough valid data for determination of the reference temperature.

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Dandos, Rostislav. "DETERMINATION OF BUSHING VERTICALITY FOR LOADING TESTS IN THE PAVILION OF TESTING FAST." In 14th SGEM GeoConference on INFORMATICS, GEOINFORMATICS AND REMOTE SENSING. Stef92 Technology, 2014. http://dx.doi.org/10.5593/sgem2014/b22/s9.023.

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Steinert, W., R. Fuchs, and H. Starken. "Inlet Flow Angle Determination of Transonic Compressor Cascades." In ASME 1991 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1991. http://dx.doi.org/10.1115/91-gt-274.

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Tests of transonic compressor cascades require special measuring techniques to determine the inlet flow angle around sonic inlet flow conditions. One of the main requirements for these methods is the ability to adjust the inlet flow angle during the test to a prescribed value. A method has been successfully applied which relies on theoretically determined suction surface velocities. The described method was applied in testing cascades at inlet Mach numbers between M1=0.75–1.18. The test results confirmed the practicability of this method.

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Li, Yingzhi, and Roman Sˇturm. "Determination of Creep Properties From Small Punch Test." In ASME 2008 Pressure Vessels and Piping Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/pvp2008-61437.

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The small punch test is one of the techniques, which can directly assess the current material properties of components on situ. The main advantages of this method are that only small amount of material is needed and no repair is required afterwards. In addition, the test itself is rather simple to perform. Since early 1980’s, the technique has been developed and applied to nuclear reactors, electric power plants for safety assessment. European researchers have carried out the pioneer work on small punch testing at the creep region. Recently the European Code of Practice documents are available for both high and low temperature properties, which summarizes the international experiences in last 20 years and provides a guide line to perform small punch test for metallic materials. This paper gives an overview of the research work on determination of creep properties from small punch test. Verification is performed by comparison of creep properties derived by small punch test and uni-axial tests. An agreement is found and shows that small punch test is able to predict reasonable creep properties of materials. Considerations how to improve the approach are also addressed. Further work is needed as available tests are still limited. This paper makes a starting point that others can improve further.

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Zhu, Xian-Kui. "Determination of Pipeline Yielding Occurred in Hydrostatic Pressure Testing." In ASME 2019 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/pvp2019-93087.

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Abstract The pipeline industry has traditionally utilized the “double stroke” concept to define line pipe yielding for limiting plastic deformation of the pipeline during hydrostatic pressure testing. Practice showed that double stroke may define a nominal yield point lying between the elastic limit and the offset yield strength. Recently, a set of field hydrostatic tests were conducted on an X70 pipeline at Enterprise Products, and the test pressure at double stroke was as high as 129% of SMYS, but the von Mises stress was less than the actual yield strength. The entire pipeline was thought in the elastic conditions at double stroke during the hydrostatic testing. It is well recognized that the classical Tresca and von Mises yield criteria determines a lower and an upper bound of the limit load at yielding, and a newly proposed Zhu-Leis yield criterion determines a medium result of the two classical solutions. Extensive full-scale tests have confirmed that the Zhu-Leis yield solution is the best prediction of experimental data on average. This paper attempts to use the more accurate Zhu-Leis yield criterion to reanalyze the real-world hydrostatic tests of the X70 pipeline to see if pipe yielding occurs and to determine pipe diameter expansion at double stroke during the hydrostatic pressure testing.

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Wang, Zhengdong, Changjun Liu, Fu-Zhen Xuan, and Shan-Tung Tu. "Determination of Material Degradation at Various Environmental Conditions." In ASME 2011 Pressure Vessels and Piping Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/pvp2011-57570.

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There are growing interests in materials and system degradation at various environmental conditions, especially for structures in fossil fuel power station, nuclear power plants and petrochemical industry. Several testing and simulation approaches have been developed to determine the degradation of material properties with the influence of corrosion environment. A simulation technology is introduced to investigate the effects of irradiation on mechanical properties for a degraded reactor pressure vessel steel. The degradation procedure combines the application of cold prestrain together with high temperature heat treatment. It is found from the results of Charpy impact tests for degraded material that there is an increase of ductile-brittle transition temperature and a trend to a decrease of upper shelf energy because of irradiation embrittlement. Evaluation procedures of temper embrittlement and hydrogen-embrittlement are described for reactor pressure vessel steel exposed to hydrogen environment. A regular coupon sample test is adopted to determine the material degradation of hydrogen processing reactors. Numerical analysis and experimental hydrogen charging technique are explored to simulate the process of hydrogen embrittlement. A critical parameter of hydrogen concentration is defined to evaluate the susceptibility of hydrogen induced cracking for reactor steels. A fatigue testing system is designed to obtain the degradation of fatigue strength for materials under the low oxygen steam environment. The system couples a steam chamber with an axial force-controlled fatigue testing machine. The fatigue tests are performed for a titanium alloy with tension-compression loading up to 107 cycles. Test results show that the fatigue strength is obviously influenced by the steam environment and the stress ratios.

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Rogers, Ted, and Joe Geary. "Surface figure determination of vibrating optical membrane." In Optical Fabrication and Testing. OSA, 2002. http://dx.doi.org/10.1364/oft.2002.omd5.

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Munoz, Alberto, Christine Ehlig-Economides, and Michael J. Economides. "Principal Permeability Determination from Multiple Horizontal Well Tests." In SPE International Conference on Horizontal Well Technology. Society of Petroleum Engineers, 1998. http://dx.doi.org/10.2118/50396-ms.

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Brown, M., L. Taylor, and T. Sadek. "Determination of chalk structure using cone penetration tests." In Chalk 2018 Engineering in Chalk. ICE Publishing, 2018. http://dx.doi.org/10.1680/eiccf.64072.509.

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Yin, Decao, and Carl M. Larsen. "On Determination of VIV Coefficients Under Shear Flow Condition." In ASME 2010 29th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/omae2010-20306.

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Long marine risers exposed to ocean currents will experience vortex induced vibrations (VIV), which may cause severe fatigue damage. VIV is, however, generally less understood than other load effects. The offshore oil industry has therefore supported an intensive research activity on VIV during the last two decades. High mode VIV model tests with long flexible riser models were initiated by the Norwegian Deepwater Programme (NDP). A 38 m horizontally towed instrumented riser was tested in uniform and linearly sheared current profiles with varying towing speed. A second series of experiments has been conducted with a motion-controlled rigid cylinder in order to find the hydrodynamic coefficients for realistic cross-section trajectories. The pipe was forced to follow periodic patterns found from the NDP tests with flexible beam. The Reynolds’ number and the non-dimensional frequency, as well the amplitude ratio was kept identical for both types of tests, ensuring that the flow conditions for these two experiments remain the same. The hydrodynamic coefficients calculated from natural trajectories show a general agreement with pure harmonic forced motion tests. A slight change of excitation regions was, however, found for cross-flow response. Another observation is that in-line excitation force coefficients have much higher values than found from pure in-line test.

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Reports on the topic "Testis determination"

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Baxter, Carey, Susan Enscore, Ellen Hartman, Benjamin Mertens, and Dawn Morrison. Nationwide context and evaluation methodology for farmstead and ranch historic sites and historic archaeological sites on DoD property. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/39842.

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The Army is tasked with managing the cultural resources on its lands. For installations that contain large numbers of historic farmsteads, meeting these requirements through traditional archaeological approaches entails large investments of personnel, time and organization capital. Through two previous projects, Engineer Research and Development Center, Construction Engineering Research Laboratory (ERDC-CERL) cultural resource management personnel developed a methodology for efficiently identifying the best examples of historic farmstead sites, and also those sites that are least likely to be deemed eligible for listing on the National Register of Historic Places. This report details testing the applicability of the methodology to regions across the country. Regional historic contexts were created to assist in the determination of “typical” farmsteads. The Farmstead/Ranch Eligibility Evaluation Form created by ERDC-CERL researchers was revised to reflect the broader geographic scope and the inclusion of ranches as a property type. The form was then used to test 29 sites at five military installations. The results of the fieldwork show this approach is applicable nationwide, and it can be used to quickly identify basic information about historic farmstead sites that can expedite determinations of eligibility to the National Register.

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Follett, Jordan R. Cone Penetrometer N Factor Determination Testing Results. Office of Scientific and Technical Information (OSTI), 2014. http://dx.doi.org/10.2172/1129801.

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Repond, J. Tests of QCD at HERA: determination of the gluon density. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/466752.

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Vinci, R., T. Delph, and R. Jaccodine. Determination of SiO2 Mechanical Behavior Via High Temperature Microtensile Testing. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada413920.

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Baumann, Peter. Beam position determination for the Test Storage Ring. Office of Scientific and Technical Information (OSTI), 1987. http://dx.doi.org/10.2172/7767265.

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Dighe, Kalpak Arvind. Determination of Transverse Impedance of Scorpius LIA Test Cell. Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/1511198.

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C.J. Byrne. Determination of Importance Evaluation for Exploratory Studies Facility (ESF) Subsurface Testing Activities. Office of Scientific and Technical Information (OSTI), 2001. http://dx.doi.org/10.2172/899934.

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S. Goodin. Determination of Importance Evaluation for Exploratory Studies Facility (ESF) Subsurface Testing Activities. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/894182.

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S. Goodin. Determination of Importance Evaluation for Exploratory Studies Facility (ESF) Subsurface Testing Activities. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/859149.

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Lee, Jusang, John E. Haddock, Dario D. Batioja Alvarez, and Reyhaneh Rahbar Rastegar. Quality Control and Quality Assurance of Asphalt Mixtures Using Laboratory Rutting and Cracking Tests. Purdue University, 2019. http://dx.doi.org/10.5703/1288284317087.

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The main objectives of this project were to review the available balanced-mix design (BMD) methodologies, understand the I-FIT and Hamburg Wheel Tracking Test (HWTT) test methods using INDOT asphalt mixtures, and to explore the application of these tests to both a BMD approach and as performance-related Quality Control (QC) and Quality Acceptance (QA) methods. Two QA mixture specimen types, plant-mixed laboratory-compacted (PMLC) and plant-mixed field-compacted (PMFC) were used in the determination of cracking and rutting parameters. Distribution functions for the flexibility index (FI) values and rutting parameters were determined for various mixture types. The effects of specimen geometry and air voids contents on the calculated Flexibility Index (FI) and rutting parameters were investigated. The fatigue characteristics of selected asphalt mixtures were determined using the S-VECD test according to different FI levels for different conditions. A typical full-depth pavement section was implemented in FlexPAVE to explore the cracking characteristics of INDOT asphalt mixtures by investigating the relationship between the FI values of QA samples with the FlexPAVE pavement performance predictions. The FI values obtained from PMFC specimens were consistently higher than their corresponding PMLC specimens. This study also found that FI values were affected significantly by variations in specimen thickness and air voids contents, having higher FI values with higher air voids contents and thinner specimens. These observations do not agree with the general material-performance expectations that better cracking resistance is achieved with lower air voids content and thicker layers. Additionally, PG 70-22 mixtures show the lowest mean FI values followed by the PG 76-22 and 64-22 mixtures. The same order was observed from the ΔTc (asphalt binder cracking index) of INDOT’s 2017 and 2018 projects. Finally, it was found that the HWTT showed reasonable sensitivity to the different characteristics (e.g., aggregate sizes, binder types, and air voids contents) of asphalt mixtures. Mixtures containing modified asphalt binders showed better rut resistance and higher Rutting Resistance Index (RRI) than those containing unmodified binders.

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