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Journal articles on the topic 'Testosterone'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Andriyanto, Aryani Sismin Satyaningtijas, Raden Yufiandri, Regina Wulandari, Vinda Mulyetti Darwin, and Santa Nova A. Siburi. "Performa dan Kecernaan Pakan Ayam Broiler yang diberi Hormon Testosteron dengan Dosis Bertingkat." Acta VETERINARIA Indonesiana 3, no. 1 (2016): 29–37. http://dx.doi.org/10.29244/avi.3.1.29-37.

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Testosteron merupakan salah satu hormon anabolik yang dapat memacu pertumbuhan massa otot dan tulang. Hormon testosteron mampu merangsang sekresi growth hormone yang berperan dalam pertumbuhan. Penelitian ini bertujuan untuk mempelajari pengaruh pemberian hormon testosteron dengan dosis bertingkat terhadap performa dan kecernaan pakan ayam broiler. Sebanyak 44 ekor ayam broiler berumur 15 hari dengan rata-rata bobot badan antara 650 ± 71 g dibagi menjadi 4 kelompok (K, T1, T2, dan T3). K adalah kelompok kontrol; T1, T2, dan T3 adalah kelompok yang diberi testosteron dosis 1, 2, dan 4 mg per ek

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Qadarsina, Qadarsina, Dasrul Dasrul, and Sri Wahyuni. "Konsentrasi Hormon Testosteron Kerbau Simeulue dan Korelasinya dengan Tingkat Umur dan Lingkar Skrotum." Jurnal Agripet 19, no. 1 (2019): 13–21. http://dx.doi.org/10.17969/agripet.v19i1.8692.

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ABSTRAK. Penelitian ini bertujuan mengetahui konsentrasi hormon testosteron kerbau Simeulue dan korelasinya dengan tingkat umur dan lingkar skrotum. Sebanyak 15 ekor kerbau Simeulue jantan dibagi dalam tiga kelompok yaitu umur 2,1-3,0 tahun; 3,1-4,0 tahun, dan 4,1-5,0 tahun. Parameter yang diamati terdiri dari lingkar skrotum dan konsentrasi hormon testosteron. Data yang diperoleh dianalisis dengan analisis varian satu arah dan selanjutnya diuji dengan uji berganda Duncan. Untuk mengetahui hubungan antara umur, lingkar skrotum dengan konsentrasi hormon testosteron digunakan analisis regresi se

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Bhasin, Shalendar. "How Does Testosterone Augment the Anabolic Response to Exercise in Frail Older Adults?" Innovation in Aging 5, Supplement_1 (2021): 295. http://dx.doi.org/10.1093/geroni/igab046.1146.

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Abstract Testosterone treatment increases muscle mass, strength, and leg power in menopausal women, hypogonadal men, older men with mobility limitation, COPD and ESRD. Testosterone's effects on muscle mass and strength are augmented by exercise training and growth hormone. Testosterone treatment improves some measures of physical performance, such as stair climbing power and aerobic capacity; the improvements in gait speed have been modest. Testosterone increases muscle mass by inducing the hypertrophy of type 1 and 2 muscle fibers, and by increasing satellite cell number. Testosterone promote

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Nave, Gideon, Amos Nadler, David Zava, and Colin Camerer. "Single-Dose Testosterone Administration Impairs Cognitive Reflection in Men." Psychological Science 28, no. 10 (2017): 1398–407. http://dx.doi.org/10.1177/0956797617709592.

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In nonhumans, the sex steroid testosterone regulates reproductive behaviors such as fighting between males and mating. In humans, correlational studies have linked testosterone with aggression and disorders associated with poor impulse control, but the neuropsychological processes at work are poorly understood. Building on a dual-process framework, we propose a mechanism underlying testosterone’s behavioral effects in humans: reduction in cognitive reflection. In the largest study of behavioral effects of testosterone administration to date, 243 men received either testosterone or placebo and

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Constantino, John N. "Dominance and aggression over the life course: Timing and direction of causal influences." Behavioral and Brain Sciences 21, no. 3 (1998): 369. http://dx.doi.org/10.1017/s0140525x9831122x.

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Studies of testosterone's effect on dominance are confounded by the effects of dominance experiences on testosterone. Furthermore, antisocial behavior tends to originate prepubertally, when testosterone levels are the same for aggressive males, nonaggressive males, and females. It seems more parsimonious to view variation in testosterone as an effect of dominance-related mood states than to invoke a reciprocal model.

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Grotzinger, Andrew D., Frank D. Mann, Megan W. Patterson, Jennifer L. Tackett, Elliot M. Tucker-Drob, and K. Paige Harden. "Hair and Salivary Testosterone, Hair Cortisol, and Externalizing Behaviors in Adolescents." Psychological Science 29, no. 5 (2018): 688–99. http://dx.doi.org/10.1177/0956797617742981.

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Although testosterone is associated with aggression in the popular imagination, previous research on the links between testosterone and human aggression has been inconsistent. This inconsistency might be because testosterone’s effects on aggression depend on other moderators. In a large adolescent sample ( N = 984, of whom 460 provided hair samples), we examined associations between aggression and salivary testosterone, hair testosterone, and hair cortisol. Callous-unemotional traits, parental monitoring, and peer environment were examined as potential moderators of hormone-behavior associatio

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Augusto Alves Alcantara, Pedro, Amanda Talys Sampaio, Marilice Zundt, et al. "Testosterone, Cortisol and Weight Gain in Confined Texel Lambs Supplemented with Commercial Probiotic and its Association with Selenium and Chromium." Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde 28, no. 5 (2024): 581–85. https://doi.org/10.17921/1415-6938.2024v28n5p581-585.

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The aim of this study was to evaluate lambs’ supplementation with the yeast Saccharomyces cerevisiae, with or without added selenium and chromium, on the plasma levels of testosterone, cortisol and weight gain. Twenty-four male Texel lambs were used, mean age of 120 days and weight 29.0 ± 2.44 kg, divided into 3 groups: G-Control (commercial feed without additives), G-Pro (commercial feed + 5 g yeast Saccharomyces cerevisiae), and G-Pro+Se/Cr (commercial feed + 3 g yeast Saccharomyces cerevisiae + 50 mg/kg organic selenium + 300 mg/kg organic chromium). Weight measurement and blood sampling we

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Fedy, Bradley C., and Bridget J. M. Stutchbury. "Testosterone Does not Increase in Response to Conspecific Challenges in the White-Bellied Antbird (Myrmeciza Longipes), A Resident Tropical Passerine." Auk 123, no. 1 (2006): 61–66. http://dx.doi.org/10.1093/auk/123.1.61.

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Abstract Resident tropical passerines that exhibit year-round territorial aggression do not fit well into the temperate-zone model, because testosterone does not increase substantially during the breeding season. We studied patterns of testosterone secretion in the White-bellied Antbird (Myrmeciza longipes), a resident tropical species in Panama that maintains territories year-round and is capable of aggression throughout the year, regardless of its stage of reproduction. Levels of plasma testosterone were low (mean = 0.30 ng mL−1) throughout the breeding and nonbreeding seasons and did not di

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Geniole, Shawn N., Tanya L. Procyshyn, Nicole Marley, et al. "Using a Psychopharmacogenetic Approach To Identify the Pathways Through Which—and the People for Whom—Testosterone Promotes Aggression." Psychological Science 30, no. 4 (2019): 481–94. http://dx.doi.org/10.1177/0956797619826970.

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Little is known about the neurobiological pathways through which testosterone promotes aggression or about the people in whom this effect is observed. Using a psychopharmacogenetic approach, we found that testosterone increases aggression in men ( N = 308) with select personality profiles and that these effects are further enhanced among those with fewer cytosine-adenine-guanine (CAG) repeats in exon 1 of the androgen receptor (AR) gene, a polymorphism associated with increased AR efficiency. Testosterone’s effects were rapid (~30 min after administration) and mediated, in part, by subjective

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Banov, Daniel, Bruce Biundo, Kendice Ip, et al. "Testosterone Therapy for Late-Onset Hypogonadism: A Clinical, Biological, and Analytical Approach Using Compounded Testosterone 0.5–20% Topical Gels." Pharmaceutics 16, no. 5 (2024): 621. http://dx.doi.org/10.3390/pharmaceutics16050621.

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Testosterone is integral to men’s sexual and overall health, but there is a gradual decline in the ageing male. The topical administration of testosterone is a valuable option as a supplement (replacement) therapy to alleviate hypogonadal symptoms. The clinical efficacy of a compounded testosterone 5% topical gel was assessed retrospectively in a male patient in his seventies by evaluating the laboratory testing of the serum total testosterone and the results of a validated androgen deficiency questionnaire. After treatment, the patient’s hypogonadal symptoms improved and the serum total testo

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Linares, Mauricio, José Luis Pruneda-Paz, Luciana Reyna, and Susana Genti-Raimondi. "Regulation of testosterone degradation in Comamonas testosteroni." Journal of Steroid Biochemistry and Molecular Biology 112, no. 1-3 (2008): 145–50. http://dx.doi.org/10.1016/j.jsbmb.2008.09.011.

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Saldes, Erick Benjamin, Alexandra Erdmier, Jai Velpula, et al. "Abstract 269: TRPM8 as a testosterone receptor: Exploring its role in prostate cancer and male behavior." Cancer Research 85, no. 8_Supplement_1 (2025): 269. https://doi.org/10.1158/1538-7445.am2025-269.

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Abstract The transient receptor potential melastatin 8 (TRPM8) channel has emerged as a critical mediator of testosterone signaling in prostate cancer (PC), influencing both tumor progression and sexually dimorphic behaviors. Our research expands upon TRPM8's role as a testosterone receptor, facilitating calcium influx that modulates cell proliferation and apoptosis in PC cells. Notably, TRPM8 mRNA is overexpressed in androgen-dependent benign PC tumors, but exhibits decreased expression in metastatic tumors, indicating a potential tumor-suppressive function in early-stage PC. This suggests th

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Balvočius, Antanas. "Vyrų sutrikusios lytinės funkcijos androgeniniai aspektai." Lietuvos chirurgija 3, no. 4 (2005): 0. http://dx.doi.org/10.15388/lietchirur.2005.4.2302.

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Antanas BalvočiusTarptautinis medicinos centras Union Clinic Vilnius,Tilto g. 1/2, VilniusEl paštas: balvociusa@delfi.lt Įvadas / tikslas Lytinių steroidinių hormonų endokrininiai sutrikimai neigiamai paveikia vyrų lytinę funkciją. Straipsnio tikslas – pateikti pagyvenusių vyrų lytinės disfunkcijos tyrimų ir gydymo rezultatus, apžvelgti mokslinę literatūrą apie endokrininę vyrų lytinės disfunkcijos patofiziologiją, diagnostiką ir gydymą. Ligoniai ir metodai Nuo lytinės disfunkcijos gydyti 64 pagyvenę (50–75 metų, vidutinis amžius 59 metai) vyrai. Erekcijos sutrikimai pagal TEFR-5 skalę svyravo

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Enter, Dorien, Philip Spinhoven, and Karin Roelofs. "Dare to Approach." Clinical Psychological Science 4, no. 6 (2016): 1073–79. http://dx.doi.org/10.1177/2167702616631499.

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Persistent fear and avoidance in patients with social anxiety disorder (SAD) has been associated with reduced testosterone levels. Because threat avoidance is a major maintaining factor in SAD, and because testosterone administration promotes social approach, we tested whether testosterone administration can directly facilitate threat approach behavior in SAD. In a double-blind, placebo-controlled study, 17 female participants with SAD received a single dose of testosterone before performing a well-established social Approach-Avoidance Task. This objective implicit measure of social motivation

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Cashdan, Elizabeth. "Why is testosterone associated with divorce in men?" Behavioral and Brain Sciences 21, no. 3 (1998): 366. http://dx.doi.org/10.1017/s0140525x9826122x.

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There is evidence that in women high levels of testosterone are associated with more sexual partners and more permissive sexual attitudes. If a similar relationship holds true for men, the higher basal testosterone levels of divorced and unmarried men may be caused by this relationship rather than by testosterone's effect on dominance striving.

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BOBOC, Daniela, Manole COJOCARU, and Natalia ROȘOIU. "THE INFLUENCE OF TESTOSTERONE ON THE BEHAVIOR OF THE AUTISTIC CHILD." Annals of the Academy of Romanian Scientists Series on Biological Sciences 13, no. 1 (2024): 120–31. http://dx.doi.org/10.56082/annalsarscibio.2024.1.120.

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Background The impact of testosterone on autism symptoms is still being studied, and the precise mechanisms are not yet fully understood. Objectives Numerous studies have been conducted to investigate the relationship between autism and testosterone levels. The biochemical analysis of testosterone is important to perform for boys, especially for those diagnosed with autism spectrum disorders who also present a high level of aggression. Materials and methods While the exact causes of autism are still unknown, researchers have been studying the relationship between autism and testosterone levels

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Gouveia, Maria, Raquel Sanches, Sara Andrade, Sara Carmona, and Carolina Ferreira. "O Papel da Testosterona na Melhoria do Desejo Sexual da Mulher Pós-Menopáusica: Uma Revisão Baseada na Evidência." Acta Médica Portuguesa 31, no. 11 (2018): 680. http://dx.doi.org/10.20344/amp.9277.

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Introduction: Female sexual dysfunction is a common problem, affecting more than 1/3 of women during their lives. The aim of this review is to review the evidence for the effectiveness of testosterone in sexual dysfunction in postmenopausal women, particularly in the improvement of sexual desire.Material and Methods: The authors searched in international databases National Guidelines Clearinghouse, Guidelines Finder, Cochrane Library and MEDLINE/PubMed, for guidelines, systematic reviews, meta-analysis and randomized controlled trials, published between January 2005 and February 2017, using th

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Md Harashid, Khadijah Abdullah, Che Mohd Nasril Che Mohd Nassir, Mohamed Ayaaz Ahmed, Rahmah Ahmad H. Osman, and Usman Jaffer. "TESTOSTERONE AND SOCIAL HIERARCHIES: FROM NEURAL MECHANISMS TO BEHAVIOURAL OUTCOMES." International Journal of Education, Psychology and Counseling 9, no. 56 (2024): 1028–41. https://doi.org/10.35631/ijepc.956064.

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Testosterone is traditionally linked to aggression and dominance, yet growing evidence indicates that its influence on social behaviour is multifaceted. This review synthesizes key findings on testosterone’s role in shaping both aggressive and prosocial forms of dominance, drawing from animal and human research. Three cornerstone papers—Watanabe and Yamamoto (2015), Terburg and Van Honk (2013), and Johnson et al. (2012)—provide a foundation for understanding how testosterone interacts with multiple neural circuits, notably the amygdala, prefrontal cortex, and reward systems. These interactions

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Sembiring, Dewi Prisca, and Dr Soetjipto. "Korelasi Antara Kadar Testosteron Total dengan Kepribadian Antisosial dan Jenis Kriminalitas pada Penghuni Lapas Jember." Jurnal Psikiatri Surabaya 6, no. 2 (2017): 79. http://dx.doi.org/10.20473/jps.v6i2.19431.

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Latarbelakang. Hormon testosterone telah lama diasosiasikan dengan berbagai macam sifat pria pada umumnya dan berhubungan dengan perilaku agresif, dominasi dan kepribadian antisocial dalam berbagai kondisi masyarakat, bahkan dalam beberapa kasus disebutkan tin dakan criminal menjadi salah satu efek dari tingginya kadar hormonini.Tujuan. Korelasi antara kadar hormone testosteron total pada penghuni Lapas Jember, dengan kepribadian antisosial yang dimiliki dan jenis kriminal yang dilakukan.Metode. Studi kuantitatif cross sectional. Menggunakan form MCMI-IV dan uji kadar terstosteron total pada p

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Littleton-Kearney, Marguerite, and Patricia D. Hurn. "Testosterone as a Modulator of Vascular Behavior." Biological Research For Nursing 5, no. 4 (2004): 276–85. http://dx.doi.org/10.1177/1099800403262927.

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Male sex is an acknowledged risk factor for many forms of cardiovascular disease, and vascular disease prevalence patterns appear to be different in men versus women. The vascular properties of the principal mammalian androgen, testosterone, are complex and linked to dose, duration of exposure, presence of underlying vascular disease, and, possibly, biological sex. Data from isolated vessels and animal models suggest that pharmacological doses of testosterone, or its potent intracellular metabolite dihydrotestosterone, produce vasodilation. Testosterone’s major effect on vascular beds at physi

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Dayan, Dan, Avital Kozlovsky, Haim Tal, Noam Kariv, Mordechai Shemesh, and Abraham Nyska. "Castration prevents calcium channel blocker-induced gingival hyperplasia in beagle dogs." Human & Experimental Toxicology 17, no. 7 (1998): 396–402. http://dx.doi.org/10.1177/096032719801700706.

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1 The purpose of this study was to investigate testosterone's role on the calcium channel antagonist oxodi-pine-inducing gingival hyperplasia in a dog model. 2 Two experiments were conducted using castrated and intact male dogs. Oxodipine was administered orally for 90 days, at a dose of 24 mg/kg/day. In the first experiment, the occurrence of gingival hyperplasia was evaluated. In the second, the gingival index (GI) and gingival hyperplasia index (GHI) were recorded and correlated with serum levels of testosterone. 3 A significant positive correlation between GI, GHI and plasma testosterone w

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Osadshiy, Y., and V. Soldatkin. "Depression in men with testosterone deficiency (Preliminary results of the study)." European Psychiatry 65, S1 (2022): S319—S320. http://dx.doi.org/10.1192/j.eurpsy.2022.813.

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Introduction Clinical practice in psychiatry is shifting toward personalized approach. In other words, clinicians aim to help patients based on their individual characteristics. It’s known that testosterone play a crucial role in the regulation of the emotions specially in men. The problems of hypogonadism and its possible role as an etiological factor in the development of depression in men are available in detail. But there is no solid date about the features of depression in men with testosteron defficency and theraputic approach including testosterone replacement therapy and antidepressant

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Arini, Luh Ari. "Studi Literatur Perbedaan Ekspresi Messenger Ribonucleid Acid (mRNA) Reseptor Androgen Setelah Pemberian Testosteron antara Penis dan Kelenjar Prostat Tikus Wistar Jantan (Rattus Norvegicus) Pascakastrasi." Jurnal Kesehatan Reproduksi 6, no. 1 (2019): 29. http://dx.doi.org/10.22146/jkr.37823.

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Background: Aging process (andropause) in men will cause a decrease in testosterone hormones, in other that decrese of androgen receptor (testosteron and dhyhidrtestosterone) in target organ, can be seen from AR mRNA expression. Andropause finaly impact of male reproductive organ, so given testosterone hormone therapy is important to restore the condition. Giving testosterone hormone causes increase the expression of AR mRNA in the prostate gland and penis, but in these two organs there is a different increase.Objective: to know the difference of expression AR mRNA after administration of test

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Cheng, Jian, Weidong Hu, Thomas J. Toung, et al. "Age-Dependent Effects of Testosterone in Experimental Stroke." Journal of Cerebral Blood Flow & Metabolism 29, no. 3 (2008): 486–94. http://dx.doi.org/10.1038/jcbfm.2008.138.

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Although male sex is a well-recognized risk factor for stroke, the role of androgens in cerebral ischemia remains unclear. Therefore, we evaluated effects of testosterone on infarct size in both young adult and middle-aged rats (Wistar, 3-month versus 14-month old) and mice (C57/BL6, 3-month versus 12-month old) subjected to middle cerebral artery occlusion. In young adult groups, castrates displayed less ischemic damage as compared with intact males and castrates with testosterone replacement (Cortex: 24% in castrates versus 42% in intact versus 40% with testosterone; Striatum: 45% versus 73%

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Traustadóttir, Tinna, S. Mitchell Harman, Panayiotis Tsitouras, et al. "Long-Term Testosterone Supplementation in Older Men Attenuates Age-Related Decline in Aerobic Capacity." Journal of Clinical Endocrinology & Metabolism 103, no. 8 (2018): 2861–69. http://dx.doi.org/10.1210/jc.2017-01902.

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Abstract Context Testosterone increases skeletal muscle mass and strength, but long-term effects of testosterone supplementation on aerobic capacity, or peak oxygen uptake (V̇O2peak), in healthy older men with low testosterone have not been evaluated. Objective To determine the effects of testosterone supplementation on V̇O2peak during incremental cycle ergometry. Design A double-blind, randomized, placebo-controlled, parallel-group trial (Testosterone’s Effects on Atherosclerosis Progression in Aging Men). Setting Exercise physiology laboratory. Participants Healthy men aged ≥ 60 years with t

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Dreher, Jean-Claude, Simon Dunne, Agnieszka Pazderska, Thomas Frodl, John J. Nolan, and John P. O’Doherty. "Testosterone causes both prosocial and antisocial status-enhancing behaviors in human males." Proceedings of the National Academy of Sciences 113, no. 41 (2016): 11633–38. http://dx.doi.org/10.1073/pnas.1608085113.

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Although popular discussion of testosterone’s influence on males often centers on aggression and antisocial behavior, contemporary theorists have proposed that it instead enhances behaviors involved in obtaining and maintaining a high social status. Two central distinguishing but untested predictions of this theory are that testosterone selectively increases status-relevant aggressive behaviors, such as responses to provocation, but that it also promotes nonaggressive behaviors, such as generosity toward others, when they are appropriate for increasing status. Here, we tested these hypotheses

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Coviello, Andrea D., Kishore Lakshman, Norman A. Mazer, and Shalender Bhasin. "Differences in the Apparent Metabolic Clearance Rate of Testosterone in Young and Older Men with Gonadotropin Suppression Receiving Graded Doses of Testosterone." Journal of Clinical Endocrinology & Metabolism 91, no. 11 (2006): 4669–75. http://dx.doi.org/10.1210/jc.2006-0822.

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Abstract Background: Recently we found that testosterone levels are higher in older men than young men receiving exogenous testosterone. We hypothesized that older men have lower apparent testosterone metabolic clearance rates (aMCR-T) that contribute to higher testosterone levels. Objective: The objective of the study was to compare aMCR-T in older and young men and identify predictors of aMCR-T. Methods: Sixty-one younger (19–35 yr) and 60 older (59–75 yr) men were given a monthly GnRH agonist and weekly testosterone enanthate (TE) (25, 50, 125, 300, or 600 mg) for 5 months. Estimated aMCR-T

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Clay, Patrick G., and Amy I. Lam. "Testosterone Replacement Therapy for Bone Loss Prevention in HIV-Infected Males." Annals of Pharmacotherapy 37, no. 4 (2003): 582–85. http://dx.doi.org/10.1345/aph.1c345.

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OBJECTIVE: To review the use of testosterone for the prevention of bone loss in men with HIV infection. DATA SOURCES: A MEDLINE search (1966–May 2002) on the use of testosterone in osteoporosis/HIV infection was performed. A reference bibliography search was also completed. DATA SYNTHESIS: Osteopenia/osteoporosis is reported in HIV-infected men due to a myriad of factors. Sex hormone deficiency is a frequent endocrine abnormality in this population. CONCLUSIONS: In HIV-negative men, testosterone may be beneficial for preventing bone loss and hastening the resolution of fractures. Testosterone'

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Culbert, K. M., S. A. Burt, C. L. Sisk, J. T. Nigg, and K. L. Klump. "The effects of circulating testosterone and pubertal maturation on risk for disordered eating symptoms in adolescent males." Psychological Medicine 44, no. 11 (2014): 2271–86. http://dx.doi.org/10.1017/s0033291713003073.

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BackgroundTestosterone may be a biological factor that protects males against eating disorders. Elevated prenatal testosterone exposure is linked to lower levels of disordered eating symptoms, but effects emerge only after mid-puberty. Whether circulating levels of testosterone account for decreased risk for disordered eating in boys after mid-puberty is currently unknown; however, animal data support this possibility. In rodents, prenatal testosterone's masculinizing effects on sex-differentiated behaviors emerge during puberty when circulating levels of testosterone increase and ‘activate’ t

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Harris, Autumn N., Hyun-Wook Lee, Jill W. Verlander, and I. David Weiner. "Testosterone modulates renal ammonia metabolism." American Journal of Physiology-Renal Physiology 318, no. 4 (2020): F922—F935. http://dx.doi.org/10.1152/ajprenal.00560.2019.

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There are substantial sex differences in renal structure and ammonia metabolism that correlate with differences in expression of proteins involved in ammonia generation and transport. This study determined the role of testis-derived testosterone in these differences. We studied 4-mo-old male C57BL/6 mice 4 and 8 wk after either bilateral orchiectomy (ORCH) or sham-operated control surgery and determined the effect of testosterone replacement to reverse the effects of ORCH. Finally, we determined the cellular expression of androgen receptor (AR), testosterone’s canonical target receptor. ORCH d

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Maharjan, Dhruba Tara, Ali Alamdar Shah Syed, Guan Ning Lin, and Weihai Ying. "Testosterone in Female Depression: A Meta-Analysis and Mendelian Randomization Study." Biomolecules 11, no. 3 (2021): 409. http://dx.doi.org/10.3390/biom11030409.

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Testosterone’s role in female depression is not well understood, with studies reporting conflicting results. Here, we use meta-analytical and Mendelian randomization techniques to determine whether serum testosterone levels differ between depressed and healthy women and whether such a relationship is casual. Our meta-analysis shows a significant association between absolute serum testosterone levels and female depression, which remains true for the premenopausal group while achieving borderline significance in the postmenopausal group. The results from our Mendelian randomization analysis fail

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Dănciulescu Miulescu, Rucsandra, Suzana Dănoiu, Denisa Margină, Sorin Păun, and Cătălina Poiană. "Dynamics of Prostate-Specific Antigen Levels During Treatment with Testosterone Undecanoate in Patients with Type 2 Diabetes Mellitus." Romanian Journal of Diabetes Nutrition and Metabolic Diseases 19, no. 4 (2012): 397–403. http://dx.doi.org/10.2478/v10255-012-0046-9.

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AbstractObjectives. Prostate-specific antigen (PSA) is the most used and validated marker ofprostate cancer risk. The aim of this study was to assess PSA levels during treatmentwith testosteronum undecanoat in patients with type 2 diabetes (T2DM). Material and Methods. We evaluated 38 T2DM patients aged between 48 and 61 years withconfirmed hypogonadism. 1000 mg testosterone undecanoate was injectedintramuscular every 10 to 14 weeks. Total testosterone and PSA levels were assessedat baseline and after 6, 12, 24 months of treatment. Results. The average age was55.03 ± 2.40 years and 3 patients

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Pruneda-Paz, José Luis, Mauricio Linares, Julio E. Cabrera, and Susana Genti-Raimondi. "TeiR, a LuxR-Type Transcription Factor Required for Testosterone Degradation in Comamonas testosteroni." Journal of Bacteriology 186, no. 5 (2004): 1430–37. http://dx.doi.org/10.1128/jb.186.5.1430-1437.2004.

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ABSTRACT We have identified a new steroid-inducible gene (designated teiR [testosterone-inducible regulator]) in Comamonas testosteroni that is required for testosterone degradation. Nucleotide sequence analysis of teiR predicts a 391-amino-acid protein which shows homology between residues 327 and 380 (C-terminal domain) to the LuxR helix-turn-helix DNA binding domain and between residues 192 and 227 to the PAS sensor domain. This domain distribution resembles that described for TraR, a specific transcriptional regulator involved in quorum sensing in Agrobacterium tumefaciens. Analysis of the

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Putri, Hylda Khairah, Muhammad Zairin Jr., Odang Carman та Iis Diatin. "The use of different 17β-estradiol hormone doses and water temperatures to control cannibalism in catfish Clarias gariepinus seed". Jurnal Akuakultur Indonesia 19, № 2 (2020): 171–80. http://dx.doi.org/10.19027/jai.19.2.171-180.

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Cannibalism is a major problem in the intensive catfish hatchery that caused high mortality. This phenomenon is allegedly due to the high level of testosterone hormones in the early larvae and seed stages. Testosterone is a maternal steroid hormone that is transferred directly by the parent to the egg. Catfish broodstock has high testosterone levels during the gonad maturation phase and it enters the eggs during the process of vitellogenesis. A high level of testosterone is considered to cause catfish seeds to behave aggressively and subsequently encourage cannibalism. This testosterone level

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Lazarov, Georgi, and Vladislav Mladenov. "PERMANENT LOW NORMAL TESTOSTERONE LEVELS AND SEMINOLOGICAL DAMAGES IN MEN FROM 37 TO 45 YEARS OLD." Journal of IMAB - Annual Proceeding (Scientific Papers) 29, no. 2 (2023): 5009–13. http://dx.doi.org/10.5272/jimab.2023292.5009.

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In our practice, we are increasingly seeing men aged from 37 to 45 years' old who have permanent low normal testosterone levels. Aim: We set out to investigate whether there is an association between permanent low normal testosterone levels and negative change in seminal fluid parameters in young men. Patients and Methods: For the period from January 2013 to December 2015 at the Andrology office at Hospital "St. Sofia" we examined 73 men aged 37 to 45 years with normal or elevated body mass index, permanent low normal testosterone level, and negative change in seminal fluid parameters. In orde

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Ibero, Juan, Beatriz Galán, Eduardo Díaz, and José L. García. "Testosterone Degradative Pathway of Novosphingobium tardaugens." Genes 10, no. 11 (2019): 871. http://dx.doi.org/10.3390/genes10110871.

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In this work, we have shown that Novosphingobium tardaugens NBRC 16725 (strain ARI-1), a bacterial strain that was isolated due to its capacity to mineralize the estrogenic endocrine compound 17β-estradiol, is also able to mineralize testosterone, the androgenic endocrine compound. Using in silico analysis, we predicted a new putative steroid degradation (SD) gene cluster in strain ARI-1, which resembles genes involved in testosterone degradation in Comamonas testosteroni and other testosterone degrading bacteria like Actinobacteria (like Rhodococcus and Mycobacteria genera) although with sign

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Rice, Timothy R., and Leo Sher. "Low testosterone levels in aging men may mediate the observed increase in suicide in this age group." International Journal on Disability and Human Development 16, no. 1 (2017): 123. http://dx.doi.org/10.1515/ijdhd-2016-0007.

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Abstract This short communication suggests that there may be biological in addition to psychosocial reasons underlying the rise in suicide among older men. Testosterone, the major male sex hormone, has attracted interest as a putative biological mediator of suicide risk, but observational data have been mixed. Age stratification may reveal that high levels of testosterone in adolescents and young adults but low levels in the elderly may mediate suicide risk. A putative age-testosterone-suicide differential may be mediated by divergent central nervous system architecture between adolescents and

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Lazarov, Georgi, Philip Kumanov, and Vladislav Mladenov. "PERMANENT LOW NORMAL TESTOSTERONE AND LOWER URINARY TRACT SYMPTOMS IN MEN 35 - 45 YEARS OF AGE." Journal of IMAB - Annual Proceeding (Scientific Papers) 29, no. 1 (2023): 4814–19. http://dx.doi.org/10.5272/jimab.2023291.4814.

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In our outpatient practice, we are increasingly seeing men aged 35 to 45 years who have permanent low normal testosterone levels. Aim We set out to investigate whether there is an association between permanent low normal testosterone levels and lower urinary tract symptoms in young men. Patients and Methods For the period from January 2013 to December 2015 at the Andrology office at Hospital "St. Sofia", we examined 73 men aged 35 to 45 years with normal or elevated body mass index, permanent low normal testosterone level and micturition disorders. In order to compare the results we obtained,

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Cross, Ericha, та Charles E. Roselli. "17β-Estradiol rapidly facilitates chemoinvestigation and mounting in castrated male rats". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 276, № 5 (1999): R1346—R1350. http://dx.doi.org/10.1152/ajpregu.1999.276.5.r1346.

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Testosterone and estradiol act synergistically to stimulate male sexual behavior. Previous studies demonstrated that testosterone’s actions are mediated genomically. Attempts to show that estradiol acts in a similar fashion have been inconclusive. However, estrogens have been shown to exert short-latency effects by acting directly on neuronal membranes. The present experiment examined whether testosterone or estradiol rapidly facilitates copulatory behaviors in castrated sexually experienced rats. Within 35 min of administration, estradiol stimulated chemoinvestigation and frequency of mountin

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Huang, Grace, Guilherme V. Rocha, Karol M. Pencina, et al. "Circulating Biomarkers of Testosterone’s Anabolic Effects on Fat-Free Mass." Journal of Clinical Endocrinology & Metabolism 104, no. 9 (2019): 3768–78. http://dx.doi.org/10.1210/jc.2019-00505.

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Abstract Background Biomarkers that predict response to anabolic therapies could expedite the development of function-promoting anabolic drugs. This study aimed to identify serum biomarkers that are responsive to testosterone administration and associated with increases in fat-free mass (FFM). Methods Serum samples were obtained from the 5α-Reductase Trial, a randomized trial that compared the effects of graded doses of testosterone enanthate for 20 weeks in healthy men randomized with placebo or dutasteride (dual SRD5A inhibitor). Testosterone’s effects on FFM or strength measures did not dif

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Ishrat, Sultana, Mahmood Alam Junaid, Ali Humaira, and Noureen Shazia. "Analysis and Comparison of Total, Bio-available and Free Testosterone Levels in Various Age Groups of Men." Chemistry Research Journal 3, no. 2 (2018): 181–86. https://doi.org/10.5281/zenodo.13923732.

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In recent years several studies recommended the estimation of total as well as bio-available and free testosterone levels to assess the variations provided by the measurements and thus developing the foundation for interpreting hormone status in all groups of men. Therefore present study documents the current testosterone status i.e. total, free and bio-available, including sex hormone binding globulin (SHBG) in variable age groups of men aged 16-24 yrs “young” (n = 26), 25-35 yrs “adult” (n = 22), 36-50 yrs “middle aged” (n = 33) and 51-70 yrs “older&

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Holmes, Shaletha, Meharvan Singh, Chang Su, and Rebecca L. Cunningham. "Effects of Oxidative Stress and Testosterone on Pro-Inflammatory Signaling in a Female Rat Dopaminergic Neuronal Cell Line." Endocrinology 157, no. 7 (2016): 2824–35. http://dx.doi.org/10.1210/en.2015-1738.

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Parkinson's disease, a progressive neurodegenerative disorder, is associated with oxidative stress and neuroinflammation. These pathological markers can contribute to the loss of dopamine neurons in the midbrain. Interestingly, men have a 2-fold increased incidence for Parkinson's disease than women. Although the mechanisms underlying this sex difference remain elusive, we propose that the primary male sex hormone, testosterone, is involved. Our previous studies show that testosterone, through a putative membrane androgen receptor, can increase oxidative stress–induced neurotoxicity in dopamin

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Samsudewa, D., S. S. Capitan, C. C, Sevilla, R. S. A. Vega, and P. P. Ocampo. "Body measurements and testosteron level of male Timor deer (Rusa timorensis) at various hierarchies." Journal of the Indonesian Tropical Animal Agriculture 42, no. 4 (2017): 227. http://dx.doi.org/10.14710/jitaa.42.4.227-232.

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The aim of this research was to observe body (neck, chest and scrotum) circumferences and testosterone level of α-male, β-male and subordinate male Timor deer reared under captivity after establisment of the dominance hierarchy. Twelve males (51 ± 6 months old; 68.29 ± 8.41 kg body weight and in same antler stages) were used in this research. The bucks was grouped into three stall each containing four bucks. ELISA kit and tape measurements were used for plasma Testosterone assay and body measurement, respectively. Data was collected before and 43 days after establishment of the dominance hiera

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&NA;. "Testosterone." Reactions Weekly &NA;, no. 1376 (2011): 28–29. http://dx.doi.org/10.2165/00128415-201113760-00093.

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&NA;. "Testosterone." Reactions Weekly &NA;, no. 1381 (2011): 28. http://dx.doi.org/10.2165/00128415-201113810-00101.

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&NA;. "Testosterone." Reactions Weekly &NA;, no. 1385 (2012): 42. http://dx.doi.org/10.2165/00128415-201213850-00154.

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&NA;. "Testosterone." Reactions Weekly &NA;, no. 1388 (2012): 29. http://dx.doi.org/10.2165/00128415-201213880-00114.

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&NA;. "Testosterone." Reactions Weekly &NA;, no. 718 (1998): 12. http://dx.doi.org/10.2165/00128415-199807180-00029.

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&NA;. "Testosterone." Reactions Weekly &NA;, no. 759 (1999): 12. http://dx.doi.org/10.2165/00128415-199907590-00035.

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&NA;. "Testosterone." Reactions Weekly &NA;, no. 1163 (2007): 24. http://dx.doi.org/10.2165/00128415-200711630-00074.

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