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Journal articles on the topic 'Tetanus – Vaccination'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 January 2023

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1

Cheng, Alvan, Angie Ghanem-Uzqueda, Nicole A. Hoff, Hayley Ashbaugh, Reena H. Doshi, Patrick Mukadi, Roger Budd, et al. "Tetanus seroprotection among children in the Democratic Republic of the Congo, 2013–2014." PLOS ONE 17, no. 5 (May 19, 2022): e0268703. http://dx.doi.org/10.1371/journal.pone.0268703.

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Background Tetanus is a potentially fatal disease that is preventable through vaccination. While the Democratic Republic of the Congo (DRC) has continued to improve implementing routine vaccination activities throughout the country, they have struggled to maintain high childhood vaccine coverage. This study aims to examine the seroprevalence of tetanus in children 6 to 59 months to identify areas for intervention and improvement of vaccination coverage. Methods In collaboration with the 2013–2014 Demographic and Health Survey, we assessed the seroprevalence of tetanus antibodies among children

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2

Hirka, E. I., and M. S. Popov. "IMMUNOLOGICAL EFFICIENCY OF THE TETANUS TOXOID USE FOR THE URGENT SPECIFIC TETANUS PREVENTION IN PATIENTS WITH THE WOUND INFECTION." Kharkiv Surgical School, no. 3 (March 20, 2020): 54–57. http://dx.doi.org/10.37699/2308-7005.3.2020.11.

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Summary. Aim. The present study aimed to analyze the effectiveness of tetanus toxoid administration during the urgent specific tetanus prevention. Materials and methods. The determination of tetanus immunity levels in patients with the wound infection before immunization, then 2 and 4 weeks after vaccination. Studies of blood sera of patients were carried out in dynamics by enzyme-linked immunosorbent assay using a set of test systems for determining IgG antibodies to tetanus toxoid «Clostridium tetani toxin IgG», ELISA, Nova Tec Immundiagnostica GmbH, Germany. Results of the study were

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3

Langhorst, Silvan Elias, Niklas Frahm, Michael Hecker, Pegah Mashhadiakbar, Barbara Streckenbach, Julia Baldt, Felicita Heidler, and Uwe Klaus Zettl. "Vaccination Coverage against Tetanus, Diphtheria, Pertussis and Poliomyelitis and Validity of Self-Reported Vaccination Status in Patients with Multiple Sclerosis." Journal of Personalized Medicine 12, no. 5 (April 23, 2022): 677. http://dx.doi.org/10.3390/jpm12050677.

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Multiple sclerosis (MS) is a chronic immune-mediated disease with a neurodegenerative component of the central nervous system. Immunomodulatory therapy can increase the risk of infection, which is a particular risk for MS patients. Therefore, a complete vaccination status is of utmost importance as protection against vaccine-preventable infectious diseases. Our aim was to investigate the vaccination status, vaccination card knowledge and the vaccination behavior of MS patients with regard to vaccinations against tetanus, diphtheria, pertussis and poliomyelitis. Three hundred twenty-seven patie

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Fletcher, Meghan, Shannon Rankin, and Preeyaporn Sarangarm. "The Effect of Pharmacy-Driven Education on the Amount of Appropriately Administered Tetanus Vaccines in the Emergency Department." Hospital Pharmacy 54, no. 1 (April 18, 2018): 45–50. http://dx.doi.org/10.1177/0018578718769239.

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Background: Tetanus vaccinations for wound prophylaxis are routinely administered in emergency departments (ED). Current recommendations from the Centers for Disease Control and Prevention (CDC) and Advisory Committee on Immunization Practices (ACIP) regarding tetanus administration for wound prophylaxis differentiate between the tetanus and diphtheria (Td) and the tetanus, diphtheria, acellular pertussis (Tdap) formulations and when they should be administered. Lack of knowledge regarding these recommendations, different formulations, and techniques to locate patient immunization history can

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5

Cassimos, Dimitrios C., Evgnosia Effraimidou, Snezana Medic, Theoharis Konstantinidis, Maria Theodoridou, and Helena C. Maltezou. "Vaccination Programs for Adults in Europe, 2019." Vaccines 8, no. 1 (January 20, 2020): 34. http://dx.doi.org/10.3390/vaccines8010034.

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Background: While all European countries implement vaccination programs for children, there are gaps in terms of vaccination programs for adults. Methods: We studied the 2019 vaccination policies for adults in 42 European countries. Results: Vaccination programs for adults were in place in all countries. However, there were considerable differences between countries in terms of number of vaccinations, target populations and frame of implementation (recommended or mandatory vaccinations). In particular the following vaccination policies were in place: influenza (42 countries), tetanus (31), dip

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Seo, Seung Won, Jaewon Lee, Bong-Goo Yoo, Jehun Kim, and So-Young Huh. "Autonomic instability in severe tetanus: a case report." Annals of Clinical Neurophysiology 23, no. 2 (October 29, 2021): 117–20. http://dx.doi.org/10.14253/acn.2021.23.2.117.

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Tetanus is an infectious disease of the nervous system caused by Clostridium tetani, and is characterized by tonic muscle contractions, painful spasms, and autonomic dysfunction. Severe autonomic dysfunction associated with tetanus can be life-threatening. We present a 62-year-old female who experienced lockjaw after an ankle fracture. The patient was diagnosed with tetanus and received tetanus immunoglobulin and a vaccination. The patient subsequently experienced labile hypertension. This case highlights the challenge and importance of managing cardiovascular instability.

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7

Segarra-Newnham, Marisel. "Tracking Vaccination Rates among HIV-Positive Patients with a Computerized Reminder System." Hospital Pharmacy 38, no. 8 (August 2003): 758–62. http://dx.doi.org/10.1177/001857870303800814.

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Objective This study deterimined vaccination rates at a Veterans Affairs HIV clinic before and after the 1997 implementation of a computerized reminder system. Methods Before implementation of a computerized reminder system, vaccinations were not always recorded on patients' medical records. After implementation, vaccinations were documented in the computer record and the system alerted providers when patients became due for a pneumococcal vaccine, tetanus booster, or other immunization. Charts for all patients (n = 211) enrolled in the HIV clinic were assessed for vaccination dates. Vaccinati

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Hao, Nguyen Van, Nguyen Ngoc My Huyen, Nguyen Thi Han Ny, Vo Thi Nhu Trang, Nguyen Van Minh Hoang, Duong Bich Thuy, Nguyen Thanh Nguyen, et al. "The Role of the Gastrointestinal Tract in Toxigenic Clostridium tetani Infection: A Case-Control Study." American Journal of Tropical Medicine and Hygiene 105, no. 2 (August 11, 2021): 494–97. http://dx.doi.org/10.4269/ajtmh.21-0146.

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ABSTRACT. Tetanus arises from wound contamination with Clostridium tetani, but approximately one fifth of patients have no discernable entry wound. Clostridium tetani is culturable from animal feces, suggesting the gastrointestinal tract could be an endogenous reservoir or direct-entry portal, but human data are lacking. In this study of 101 Vietnamese adults with tetanus and 29 hospitalized control subjects, admission stool samples were cultured for C. tetani. Anti-tetanus toxin antibodies were measured by ELISA. Clostridium tetani toxigenicity was evaluated using polymerase chain reaction an

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9

Mortelmans, Luc J. M., Colpin Gert, and Jutten Y. C. Guido. "Thrombocytopenia after tetanus vaccination." European Journal of Emergency Medicine 16, no. 6 (December 2009): 345–46. http://dx.doi.org/10.1097/mej.0b013e328321b7a4.

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10

Puri, Ajit S. "Tetanus Following Smallpox Vaccination." Journal of Nepal Medical Association 5, no. 1 (January 1, 2003): 53–56. http://dx.doi.org/10.31729/jnma.924.

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11

Moura, Sofia, and Maria do Rosário O. Martins. "Determinants of Tetanus Vaccination among Adult Immigrants: Findings from the Portuguese National Health Survey 2014." International Journal of Environmental Research and Public Health 16, no. 9 (May 9, 2019): 1619. http://dx.doi.org/10.3390/ijerph16091619.

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Vaccination is an effective strategy to prevent tetanus, and in Portugal this service is provided free of charge. Despite this, immigrants reported lower tetanus vaccination coverage than did Portuguese natives. The objective of this study was to identify sociodemographic, migration-related, and access-to-care factors associated with tetanus vaccination coverage among adult immigrants, using data from the Portuguese National Health Survey 2014. For the sample of 1277 immigrants aged ≥18 years, we estimated self-reported tetanus vaccination within the preceding 10 years and its determinants usi

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Sayar, Merve Sefa, Mustafa Özgür Akca, Ali Asan, Ali Gümüş, Sibel Yorulmaz Göktaş, İsmail Necati Hakyemez, Özgür Dağlı, and Çınar Öztürk. "Tetanus immunization among healthcare professionals: cross-sectional study in Turkey." Journal of Infection in Developing Countries 16, no. 10 (October 31, 2022): 1596–601. http://dx.doi.org/10.3855/jidc.16787.

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Introduction: Vaccine-preventable diseases can be effectively managed through timely vaccine booster doses. In this study, the tetanus vaccination status of healthcare professionals and their level of knowledge about tetanus vaccination were investigated Methodology: The data were obtained through a survey questionnaire from 336 healthcare professionals. The survey participants were recruited on a voluntary basis among the personnel working in a tertiary hospital between 1 July 2021 and 30 September 2021. The participants were asked about their tetanus vaccination status and general awar

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13

Candido, R. "The perception of Italian diabetologists on anti-influenza and anti-diphtheria-tetanus-pertussis vaccinations in subjects with diabetes mellitus: the AMD survey." Journal of AMD 22, no. 3 (October 2019): 99. http://dx.doi.org/10.36171/jamd19.22.3.03.

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Diabetes mellitus is associated with an increased incidence of some infections and a greater severity and/or frequency of complications related to these diseases. Influenza is characterized by an increased severity of clinical course and risk of complications, especially in diabetic patients who are more susceptible to influenza infection. For these reasons, the Italian Vaccine Prevention Plan 2017-19 provides an active and free offer of influenza vaccine for the diabetic subjects. In addition, among the vaccinations recommended by the Italian Prevention Plan in adults, including the diabetes

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Amoak, Daniel, Nancy Osei Kye, Florence Wullo Anfaara, Yujiro Sano, and Roger Antabe. "Maternal Tetanus Toxoid Vaccination in Benin: Evidence from the Demographic and Health Survey." Vaccines 11, no. 1 (December 29, 2022): 77. http://dx.doi.org/10.3390/vaccines11010077.

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Tetanus toxoid vaccination is critical for improving maternal and child health. Yet, the prevalence and correlates of maternal tetanus toxoid vaccination coverage remain largely underexplored in Benin where infant and child mortality rates are high. Using the 2017–18 Benin Demographic and Health Survey, we apply logistic regression analysis to address this void in the literature. We find that overall maternal vaccination coverage is 69%. A range of demographic, health care, and socioeconomic factors are associated with maternal tetanus toxoid vaccination coverage. Women aged 20–34 (OR = 0.84,

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Veronese, Nicola, Giusy Vassallo, Maria Armata, Laura Cilona, Salvatore Casalicchio, Roberta Masnata, Claudio Costantino, et al. "Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study." Vaccines 10, no. 4 (April 3, 2022): 555. http://dx.doi.org/10.3390/vaccines10040555.

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It is known that influenza, herpes zoster, pneumococcal and pertussis infections may increase morbidity and mortality in older people. Vaccinations against these pathogens are effective in older adults. Frailty seems to be an important determinant of vaccination rates, yet data supporting this association are still missing. Therefore, we aimed to investigate the prevalence of four recommended vaccinations (influenza, herpes zoster, pneumococcal and diphtheria-tetanus-pertussis) and the association with multidimensional frailty assessed using a self-reported comprehensive geriatric assessment t

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Möller, Jens, Max Edmund Kraner, and Andreas Burkovski. "More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines." Proteomes 7, no. 2 (April 16, 2019): 15. http://dx.doi.org/10.3390/proteomes7020015.

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Clostridium tetani is the etiological agent of tetanus, a life-threatening bacterial infection. The most efficient protection strategy against tetanus is a vaccination with the C. tetani neurotoxin, which is inactivated by formaldehyde-crosslinking. Since we assumed that besides the tetanus toxin, other proteins of C. tetani may also be present in toxoid preparations, we analyzed commercially available vaccines from different countries in respect to their protein content using mass spectrometry. In total 991 proteins could be identified in all five analyzed vaccines, 206 proteins were common i

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17

MUAZZAM, MUHAMMAD, SHEHZAD ADIL MANSOOR, SUMERA BADAR, Asif Nadeem, Bilal Anwar, M. Hussain Waseer, and Shoukat Ali. "TETANUS;." Professional Medical Journal 20, no. 06 (December 15, 2013): 1026–34. http://dx.doi.org/10.29309/tpmj/2013.20.06.1740.

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Background: Tetanus still remains a major public health problem in Pakistan like in most other developing countries, with ahigh morbidity and mortality. Objectives: To study the demographic profile the clinical profile, the outcome of the tetanus patients andeffectiveness of tetanus immunization coverage in district Faisalabad. Design: Retrospective record based study. Place and Duration:Surgical unit-5 DHQ Hospital, Faisalabad from January 2010 to December 2012. Subjects and Methods: All data of 198 patients oftetanus of any age and sex, diagnosed clinically was collected, compiled and analyz

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18

Chawla, Dr Anil Kumar, Chandrani Das, Paramdeep Singh, Mansha Tiwari, and Dr Seema Chaudhary. "Production of tetanus toxin by using media substantially free from meat and blood." Asian Journal of Pharmaceutical and Clinical Research 9, no. 6 (November 1, 2016): 284. http://dx.doi.org/10.22159/ajpcr.2016.v9i6.14410.

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The present study was to redesign the conventional Mueller and Miller medium to produce tetanus toxin from Clostridium tetani. Meat based ingredients (such as Bovine Heart/ Brain/ Liver Infusion) were replaced with vegetable peptone & alternate casein hydrolysate and scaled up from 100mL to 1000mL. Modified Mueller and Miller Medium containing vegetable peptone (substitute of BHI) and alternate casein hydrolysate were used for production and scale -up of tetanus toxin. Detoxification of tetanus toxin was carried out by using formaldehyde to produce tetanus toxoid. Purification of tetanus t

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Zanetti, Giulia, Andrea Mattarei, Florigio Lista, Ornella Rossetto, Cesare Montecucco, and Marco Pirazzini. "Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin." Pharmaceuticals 14, no. 11 (November 8, 2021): 1134. http://dx.doi.org/10.3390/ph14111134.

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Tetanus neurotoxin (TeNT) is a protein exotoxin produced by Clostridium tetani that causes the deadly spastic neuroparalysis of tetanus. It consists of a metalloprotease light chain and of a heavy chain linked via a disulphide bond. TeNT binds to the neuromuscular junction (NMJ) and it is retro-axonally transported into vesicular compartments to the spinal cord, where it is released and taken up by inhibitory interneuron. Therein, the catalytic subunit is translocated into the cytoplasm where it cleaves its target protein VAMP-1/2 with consequent blockage of the release of inhibitory neurotran

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Arnold, Jana Nele, Nils Gundlach, Irina Böckelmann, and Stefan Sammito. "Impfstatus von jungen Arbeitnehmern – Eine Erhebung bei Berufsanfängern der Bundeswehr." ASU Arbeitsmedizin Sozialmedizin Umweltmedizin 2020, no. 12 (November 27, 2020): 770–75. http://dx.doi.org/10.17147/asu-2012-8715.

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Vaccination status of young employees: A survey of entrants in the Bundeswehr (German Federal Armed Forces) Objectives: In addition to the recommendations of the Standing Committee on Vaccination (STIKO) at the Robert-Koch-Institut, there are also jobrelated vaccination recommendations for special occupational groups. This applies equally to soldiers, but there is insufficient scientific data on vaccination rates. For this reason, the following study examined the extent of the vaccination gaps among young people entering the armed forces. Methods: As part of a cross-sectional study at Rotenbur

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Simovanyan, E. M., E. L. Goncharova, and V. B. Denisenko. "Tetanus is a difficult diagnosis in children." CHILDREN INFECTIONS 18, no. 4 (December 6, 2019): 70–72. http://dx.doi.org/10.22627/2072-8107-2019-18-4-70-72.

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The sporadic incidence of tetanus, the identity of symptoms with the clinical picture of a number of common neuroinfections, the high frequency of various background pathologies create difficulties in disease diagnosing in children. On the case history example of a 3 years 9 months old child with two diseases (tetanus, enterovirus infection) that developed against the background of the active form of herpesvirus infection, an algorithm of diagnostic and therapeutic measures is presented.A differential diagnosis was made between the generalized form of tetanus and meningoencephalitis of enterov

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Maltezou, Helena C., Christos Rahiotis, Maria Tseroni, Phoebus Madianos, and Ioannis Tzoutzas. "Attitudes toward Vaccinations and Vaccination Coverage Rates among Dental Students in Greece." International Journal of Environmental Research and Public Health 19, no. 5 (March 1, 2022): 2879. http://dx.doi.org/10.3390/ijerph19052879.

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Our aim was to study attitudes toward vaccinations, full vaccination rates and susceptibility rates against vaccine-preventable diseases among students attending a University Dental School. A total of 134 students were studied. Full vaccination rates were as follows: 56.5% against measles and mumps, 70.6% against rubella, 32.3% against varicella, 44.1% against hepatitis A, 45.9% against hepatitis B, and 87.7% against COVID-19. In the past decade, 63.2% of students had received a booster shot against tetanus–diphtheria, 47.8% against pertussis, and 28.1% against poliomyelitis, while 29.4% of st

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Tovikkai, Dissaruj, Jakapat Vanichanan та Kamonwan Jutivorakool. "2709. Immune Response After Diphtheria and Tetanus Toxoid Booster in Patients with Adult-Onset Immunodeficiency with Anti-interferon-γ Autoantibody". Open Forum Infectious Diseases 6, Supplement_2 (жовтень 2019): S952—S953. http://dx.doi.org/10.1093/ofid/ofz360.2386.

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Abstract Background Immunization were the key of prevention in tetanus and diphtherial disease. Nevertheless, in previous observational study, low seroprotection rate of both diphtheria and tetanus were observed in Thai healthy population. Reduced-dose diphtheria and tetanus toxoid vaccine (dT) was recommended to all adult patients regardless of immunologic status. However, data on vaccine efficacy in interferon gamma (IFN-γ) autoantibody were limited. We therefore conducted clinical study to evaluate efficacy and safety of one dose of dT in IFN-γ autoantibody patient compared with healthy ind

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Mohammed Frage, Abeer Magthop, Prof Hatim Rahamtalla Mohamed Ahmed, and Fatima Fadol Ali Osman. "Role of Health Education in Raising Tetanus Toxoid Vaccination Coverage among Pregnant Women and Mothers with Newborns in Khartoum North-Sudan, 2019." Applied Science and Innovative Research 3, no. 2 (April 30, 2019): 66. http://dx.doi.org/10.22158/asir.v3n2p66.

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<p><em>Tetanus is an acute disease caused by the toxin of a bacterium called C</em><em>lostridium tetani which is often found in soil. It is a life-threatening bacterial disease, which causes severe mortality among maternal, neonatal, and young infant. It is so serious even it can waste pregnancy, harm her baby during pregnancy or after delivery. A quasi experimental community based study was conducted among pregnant women and mothers with newborns in Khartoum North Locality from 2015-2019 with the aim to assess the effectiveness of health education intervening in raisi

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Booy, Robert, E. Richard Moxon, RichardT Mayon-White, StuartJ Aitken, Helen Griffiths, and HelenM Chapel. "Diphtheria, pertussis, and tetanus vaccination." Lancet 339, no. 8808 (June 1992): 1538–39. http://dx.doi.org/10.1016/0140-6736(92)91302-o.

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Cutts, FelicityT, Norman Begg, and NoelW Preston. "Diphtheria, pertussis, and tetanus vaccination." Lancet 339, no. 8805 (May 1992): 1355–56. http://dx.doi.org/10.1016/0140-6736(92)91999-o.

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Scherrer, Jeffrey, Joanne Salas, Timothy Wiemken, Christine Jacobs, John Morley, and Daniel Hoft. "ADULT TETANUS, DIPHTHERIA, AND PERTUSSIS VACCINATION AND INCIDENT DEMENTIA." Innovation in Aging 6, Supplement_1 (November 1, 2022): 244. http://dx.doi.org/10.1093/geroni/igac059.969.

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Abstract Adult vaccinations may reduce risk for dementia. We determined whether tetanus, diphtheria, pertussis (Tdap) vaccination is associated with lower risk for dementia. Analysis conducted with Veterans Health Affairs (VHA) administrative medical record data and replicated in private sector medical claims data. Patients were ≥65 years of age and free of dementia for 2 years prior to index date. Tdap vaccination in 2011 or 2012. Follow-up through 2018. Controls had no Tdap vaccination for the duration of follow-up. After controlling for confounding, patients with, compared to without Tdap v

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Fontanilla, Jose-Mario, Kathryn B. Kirkland, J. Gavin Cotter, and Elizabeth A. Talbot. "Ability of Healthcare Workers to Recall Previous Receipt of Tetanus-Containing Vaccination." Infection Control & Hospital Epidemiology 31, no. 6 (June 2010): 647–49. http://dx.doi.org/10.1086/652771.

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Vaccination of healthcare workers (HCWs) is an important strategy in the control and prevention of hospital outbreaks. The decision to vaccinate is often based on self-report of vaccination status. Self-report of previous receipt of tetanus-diphtheria or tetanus toxin vaccination was validated using an electronic medical record. Results showed that HCWs' self-report is reliable during a vaccination campaign.

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Imaralu, JO, AO Adekoya, AA Akadri, FE Bamidele, CC Nwankpa, and JO Sotunsa. "A Facility-Based Survey of Maternal Anti-Tetanus Vaccination Schedule Completion in a Nigerian University Community." Annals of Health Research 8, no. 2 (June 1, 2022): 141–53. http://dx.doi.org/10.30442/ahr.0802-06-165.

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Background: Maternal anti-tetanus vaccination is required to prevent maternal and neonatal tetanus. In the absence of lifetime protective dosing, repeat vaccination in every new pregnancy is needed to achieve protection of the newborn against tetanus. Objectives: To determine maternal anti-tetanus vaccination schedule completion rates and the reasons for non-completion of the schedule. Methods: This cross-sectional survey was conducted among Nigerian antenatal clinic attendees using an interviewee-administered questionnaire. Results: Most (291/347; 83.9%) respondents had rece

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SL, Medina Zavaleta. "Parental Rejection to Vaccination. A Tetanus Case Report, La Libertad, Perú." Pediatrics & Neonatal Biology Open Access 4, no. 2 (2019): 1–4. http://dx.doi.org/10.23880/pnboa-16000141.

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Introduction : Maternal and neonatal tetanus is considered an eliminated but not eradicated disease in America. However, there are still small groups of people who delay or reject immunizations causing isolated cases or outbreaks of preventable diseases such as measles or tetanus. In Peru, the National Vaccination Scheme is mandatory in all health facilities and starts within the first hours of life, when the child does not yet have the capacity to make decisions for himself, therefore, the responsibility for their heal th lies with the parents or guardians. Objective : To report a clinical ca

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Mayaki, A. M., and A. O. Talabi. "Knowledge, attitude and practice of equine vaccination among horse owners in Kano, Northern Nigeria." Nigerian Journal of Animal Production 42, no. 2 (December 30, 2015): 282–87. http://dx.doi.org/10.51791/njap.v42i2.2688.

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Equine infectious diseases continue to be one of the most important threats to the overall health of domesticated horses and proper vaccination is one the most important preventive measure against such infectious diseases. This study assessed the knowledge, attitude and practice of equine vaccination among horse owners. Forty horse owners completed the questionnaire and all the respondents were male with an average mean age of 41.9years and 50% were degree holders. A positive attitude 14(35%) toward equine vaccination was recorded. 10% had training on horse management and 19(47.5%) were aware

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Shi, Zhongkai, Mingtao Zeng, Guang Yang, Felix Siegel, Laura J. Cain, Kent R. van Kampen, Craig A. Elmets, and De-Chu C. Tang. "Protection against Tetanus by Needle-Free Inoculation of Adenovirus-Vectored Nasal and Epicutaneous Vaccines." Journal of Virology 75, no. 23 (December 1, 2001): 11474–82. http://dx.doi.org/10.1128/jvi.75.23.11474-11482.2001.

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ABSTRACT The effectiveness of vaccination programs would be enhanced greatly through the availability of vaccines that can be administered simply and, preferably, painlessly without the need for timed booster injections. Tetanus is a prime example of a disease that is readily preventable by vaccination but remains a major threat to public health due to the problems associated with administration of the present vaccine. Here we show that a protective immune response against liveClostridium tetani infection in mice can be elicited by an adenovirus vector encoding the tetanus toxin C fragment whe

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Boyarchuk, Oksana, Lubov Volyanska, Vira Synytska, Grygoriy Korytsky, and Emilia Burbela. "A Report of Five Child Tetanus Cases." Journal of Pediatric Infectious Diseases 15, no. 04 (July 30, 2018): 200–205. http://dx.doi.org/10.1055/s-0038-1667152.

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AbstractWe present five cases of generalized tetanus in children 5 to 13 years old, who were admitted to the intensive care unit of Ternopil Regional Children's Hospital (Western Ukraine) during the past 6 years (2012–2017). In our study, four children were unvaccinated and one received the full series of vaccinations. Proper vaccination in cases of infected wound may not prevent the development of the disease but improves the prognosis for recovery. Treatment of tetanus in Ukraine requires standardization of treatment protocols according to the World Health Organization recommendations, inclu

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Turan, Gökçe, and Gülnur Kul. "Tetanus immunization in pregnant women: the factors affecting maternal evaluation, tetanus vaccination and vaccination rate." Perinatal Journal 27, no. 3 (December 1, 2019): 137–42. http://dx.doi.org/10.2399/prn.19.0273003.

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Bühler, Silja, Veronika Katharina Jaeger, Sabine Adler, Bettina Bannert, Carolin Brümmerhoff, Adrian Ciurea, Oliver Distler, et al. "Safety and immunogenicity of tetanus/diphtheria vaccination in patients with rheumatic diseases—a prospective multi-centre cohort study." Rheumatology 58, no. 9 (March 15, 2019): 1585–96. http://dx.doi.org/10.1093/rheumatology/kez045.

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Abstract Objectives We aimed to assess the safety and immunogenicity of a diphtheria/tetanus vaccine booster dose in three different patient groups with rheumatic diseases on a variety of immunosuppressive/immunomodulatory medications compared with healthy controls (HCs). Methods We conducted a multi-centre prospective cohort study in Switzerland. We enrolled patients with RA, axial SpA/PsA, vasculitis (Behçet’s disease, ANCA-associated vasculitis) and HCs. Diphtheria/tetanus vaccination was administered according to the Swiss vaccination recommendations. Blood samples were drawn before vaccin

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Costantino, Claudio, Walter Mazzucco, Nicole Bonaccorso, Livia Cimino, Arianna Conforto, Martina Sciortino, Gabriele Catalano, et al. "Educational Interventions on Pregnancy Vaccinations during Childbirth Classes Improves Vaccine Coverages among Pregnant Women in Palermo’s Province." Vaccines 9, no. 12 (December 8, 2021): 1455. http://dx.doi.org/10.3390/vaccines9121455.

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Maternal immunization is considered the best intervention in order to prevent influenza infection of pregnant women and influenza and pertussis infection of newborns. Despite the existing recommendations, vaccination coverage rates in Italy remain very low. Starting from August 2018, maternal immunization against influenza and diphtheria-tetanus-pertussis were strongly recommended by the Italian Ministry of Health. We conducted a cross sectional study to estimate the effectiveness of an educational intervention, conducted during childbirth classes in three general hospitals in the Palermo metr

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Rencken, Camerin, Siraj Amanullah, Annie Gjelsvik, and Shira Dunsiger. "1646. Education Level is Associated with Tetanus Vaccine Coverage: Results from the 2016 BRFSS." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S601—S602. http://dx.doi.org/10.1093/ofid/ofz360.1510.

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Abstract Background Vaccination coverage among US adults for tetanus, a potentially fatal disease, continues to be lower than the national goals. Education has been considered to have positive impact on vaccination coverage. However, recently there have been outbreaks of vaccine preventable conditions in areas with high college completion rates. This study aims to assess the relationship between education and vaccination coverage. Specifically, we looked at the association between education level and tetanus vaccination status of the US adults. Methods Data from the 2016 Behavioral Risk Factor

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Nigussie, Jemberu, Bekahegn Girma, Alemayehu Molla, and Moges Mareg. "Tetanus Toxoid Vaccination Coverage and Associated Factors among Childbearing Women in Ethiopia: A Systematic Review and Meta-Analysis." BioMed Research International 2021 (November 8, 2021): 1–10. http://dx.doi.org/10.1155/2021/5529315.

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Background. Tetanus is a bacterial disease caused by the Clostridium tetani, which is a highly fatal, noncommunicable, and toxin-mediated disease. Globally, maternal and neonatal tetanus is a public health problem due to low maternal tetanus toxoid immunization. Ethiopia has the highest neonatal mortality and morbidity related to tetanus due to low tetanus toxoid immunization and the high number of home deliveries. The main objective of this systematic review and meta-analysis was to estimate the pooled coverage of at least two doses of tetanus toxoid immunization, and the pooled effect sizes

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Vicente-Alcalde, Nancy, Tamara Martín-Casquero, Esther Ruescas-Escolano, and José Tuells. "The Survivor: A Clinical Case of Tetanus in a Non-Immunized, Parenteral Drug User, Former Female Convict with HIV and HCV." Vaccines 8, no. 2 (June 17, 2020): 308. http://dx.doi.org/10.3390/vaccines8020308.

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Tetanus is a serious and potentially fatal systemic disease, caused by the bacterium Clostridium tetani. It is estimated that 1 million cases occur worldwide annually. Immunization programs have drastically decreased tetanus in developed countries, and the sporadic cases have been linked to injecting drug users (IDUs), immunosuppressed individuals, or those older than 65 without complete vaccination. Regrettably, it is still endemic in under-developed countries. In Spain, an average of 10 cases are notified each year, especially affecting those older than 65. The present article describes a ca

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Holland, Catherine, and Ann K. Carruth. "Exposure Risks and Tetanus Immunization in Women of Family Owned Farms." AAOHN Journal 49, no. 3 (March 2001): 130–36. http://dx.doi.org/10.1177/216507990104900305.

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A sampling pool of 4,808 farms in 10 parishes across southeast Louisiana was used to examine the risk factors of farm women who engage in activities putting them at risk for tetanus and to examine the circumstances related to vaccination. Data were collected, via stratified random sampling, in summer 1998 resulting in 657 completed interviews. Only 53.6% of women were current with a tetanus booster, having received their immunization within the past 10 years. Just as many women received tetanus vaccination following an injury or accident as for prevention. As women aged, they were less likely

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Kroon, F. P., M. J. D. van Tol, C. M. Jol-van der Zijde, R. van Furth, and J. T. van Dissel. "Immunoglobulin G (IgG) Subclass Distribution and IgG1 Avidity of Antibodies in Human Immunodeficiency Virus-Infected Individuals after Revaccination with Tetanus Toxoid." Clinical Diagnostic Laboratory Immunology 6, no. 3 (May 1, 1999): 352–55. http://dx.doi.org/10.1128/cdli.6.3.352-355.1999.

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ABSTRACT In human immunodeficiency virus (HIV)-infected individuals the amount of antibodies formed after vaccination with T-cell-dependent recall antigens such as tetanus toxoid is proportional to the peripheral blood CD4+ T-lymphocyte counts. To investigate whether the immunoglobulin G (IgG) subclass distribution and avidity of the antibodies produced after vaccination are affected as well, we gave 13 HIV-infected adults with low CD4+ T-lymphocyte counts (<200 × 106/liter; group I), 11 HIV-infected adults with intermediate CD4+ T-lymphocyte counts (≥200 × 106/liter; group II), and 5 healt

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Dilber, Embiya, Tevfik Karagöz, Kudret Aytemir, Sema Özer, Dursun Alehan, Ali Oto, and Alpay Çeliker. "Acute Myocarditis Associated With Tetanus Vaccination." Mayo Clinic Proceedings 78, no. 11 (November 2003): 1431–33. http://dx.doi.org/10.4065/78.11.1431-a.

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Macias, Vasco Coelho, and Daniela Cunha. "Psoriasis triggered by tetanus-diphtheria vaccination." Cutaneous and Ocular Toxicology 32, no. 2 (October 10, 2012): 164–65. http://dx.doi.org/10.3109/15569527.2012.727936.

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De Francisco, A., and J. Chakraborty. "Maternal recall of tetanus toxoid vaccination." Annals of Tropical Paediatrics 16, no. 1 (March 1996): 49–54. http://dx.doi.org/10.1080/02724936.1996.11747803.

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Bleul, G. "Failure to thrive after tetanus vaccination." British Homoeopathic journal 85, no. 2 (April 1996): 87. http://dx.doi.org/10.1016/s0007-0785(96)80203-1.

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Cozzani, E., M. Cacciapuoti, A. .Parodi, and A. Rebora. "Pemphigus following tetanus and diphtheria vaccination." British Journal of Dermatology 147, no. 1 (July 2002): 180–95. http://dx.doi.org/10.1046/j.1365-2133.2002.47958.x.

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Gindi, Michael, Peter Oravitz, Regina Sexton, Mikhail Shpak, and Anita Eisenhart. "Unreliability of reported tetanus vaccination histories." American Journal of Emergency Medicine 23, no. 2 (March 2005): 120–22. http://dx.doi.org/10.1016/j.ajem.2004.03.015.

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Petráš, Oleár, Molitorisová, Dáňová, Čelko, Nováková, Štefkovičová, Krištúfková, Malinová, and Lesná. "Factors Influencing Persistence of Diphtheria Immunity and Immune Response to a Booster Dose in Healthy Slovak Adults." Vaccines 7, no. 4 (October 7, 2019): 139. http://dx.doi.org/10.3390/vaccines7040139.

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We assessed the long-term persistence of humoral immunity against diphtheria in adults with childhood vaccination and the immunogenicity of a booster dose considering demographic, behavioural and vaccinating factors. We conducted a trial in 200 healthy Slovak adults aged 24–65 years, immunised against diphtheria in childhood and against tetanus at regular 10–15 year intervals, and receiving a dose of a tetanus-diphtheria toxoid vaccine. The response was determined by ELISA antibody concentrations of paired sera before and at 4 weeks post-vaccination. A seroprotection rate of 21% (95% confidenc

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Ahmed, Mahir, Bayan Alorinan, Abdullah AlYemni, Mohammed Albakri, Mohamme Alahmari, Ayan Hassan, Abdulaziz Alrahili, Abdullah Alfawzan, Abdulrahman Alazzouni, and Abdulaziz Alansari. "Vaccines for adults: a review of recent literature." International Journal Of Community Medicine And Public Health 5, no. 11 (October 25, 2018): 4947. http://dx.doi.org/10.18203/2394-6040.ijcmph20184601.

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Vaccinations in adults and older patients are of special importance due to two main reasons: physiological and anatomical alterations in the body as it ages, making diseases more serious and possibly fatal, and so that adult individuals have a decreased immunological response when they are exposed to infections. Major adult vaccination includes influenza, pneumococcal pneumonia and meningitis, pertussis, tetanus, diphtheria, and hepatitis. In this study, our aim was to understand the recent updates on adult immunization and their efficacy in disease prevention. We conducted this review using a

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Petrovic, Vladimir, Zorica Seguljev, Mladen Petrovic, and Svetlana Ilic. "Epidemiological characteristics of tetanus in Vojvodina." Medical review 59, no. 11-12 (2006): 551–55. http://dx.doi.org/10.2298/mpns0612551p.

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Introduction. Vojvodina is an endemic area for tetanus. Material and Methods. Epidemiological characteristics of tetanus were analyzed based on registered cases of disease and death in the period 1960 - 2004, and epidemiological investigation of 50 registered cases during the last 10 years of this period. Epidemiological characteristics were analyzed chronologically, demographically and topographically. Results and Discussion. During the period of observation, the incidence rate of tetanus declined steadily. Due to immunization and extremely high coverage, tetanus has been practically eliminat

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