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Journal articles on the topic 'Tetanus'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 June 2025

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1

Dewata, Intan Permata, and I. Ketut Sumada. "Tetanus Generalisata pada Pasien Luka Bakar dan Komplikasinya." Action Research Literate 9, no. 1 (January 29, 2025): 270–77. https://doi.org/10.46799/arl.v9i1.2614.

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Tetatus merupakan penyakit infeksi akut yang disebabkan oleh bakteri gram positif basil anaeorb Clostridium Tetani. Bakteri ini dapat menghasilkan toksin tetanospasmin yang dapat menyebabkan kelumpuhan spastik dengan menghalangi pelepasan Asam Gamma-Aminobutyric (GABA) yang muncul sebagai peningkatan kontraksi otot rangka ditandai dengan adanya gejala spasme otot berat dan periodik. Tetanus umum sering kali dimulai dengan trismus yang berkembang menjadi kekakuan nuchal, kekakuan perut, dan spasme tetanik pada ekstremitas. Laporan ini menampilkan kasus pasien laki-laki berusia 52 tahun dengan t

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2

Celichowski, Jan, and Kazimierz Grottel. "The influence of a doublet of stimuli at the beginning of the tetanus on its time course." Acta Neurobiologiae Experimentalis 58, no. 1 (March 31, 1998): 47–53. http://dx.doi.org/10.55782/ane-1998-1258.

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The influence of a pair of stimuli generated in a short time sequence (doublet) at the beginning of stimulation on the time course of the following tetanus was investigated. Experiments were performed on single motor units in rat's medial gastrocnemius. The doublet evoked an increase in tetanic tension, tetanic fusion and the area under tension record. These effects were measured in tetani fused to varying degrees. It was found that for all types of motor units the strongest influence of the doublet was observed in half- fused tetani. Moreover, the doublet influenced the first part of tetanus

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3

Carp, J. S., P. A. Herchenroder, X. Y. Chen, and J. R. Wolpaw. "Sag During Unfused Tetanic Contractions in Rat Triceps Surae Motor Units." Journal of Neurophysiology 81, no. 6 (June 1, 1999): 2647–61. http://dx.doi.org/10.1152/jn.1999.81.6.2647.

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Sag during unfused tetanic contractions in rat triceps surae motor units. Contractile properties and conduction velocity were studied in 202 single motor units of intact rat triceps surae muscles activated by intra-axonal (or intra-myelin) current injection in L5 or L6 ventral root to assess the factors that determine the expression of sag (i.e., decline in force after initial increase during unfused tetanic stimulation). Sag was consistently detected in motor units with unpotentiated twitch contraction times <20 ms. However, the range of frequencies at which sag was expressed varied among

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4

Ćakić, Elena, Suzana Hađina, Krešimir Martinković, Vladimir Stevanović, Matko Perharić, Iva Šmit, Josipa Habuš, and Zrinka Štritof. "Tetanus u pasa." Veterinarska stanica 53, no. 6 (April 29, 2022): 757–68. http://dx.doi.org/10.46419/vs.53.6.10.

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Tetanus je akutna zarazna bolest u pasa koja nastaje uslijed djelovanja neurotoksina bakterije C. tetani. Ulazna vrata su najčešće ubodne rane ili ozljede na koži. Inkubacija može trajati u vremenskom rasponu od tri dana do tri tjedna. Razlikujemo dva klinička oblika bolesti: lokalizirani i generalizirani. Kod lokaliziranog oblika vidljiva je ukočenost ekstremiteta na kojem se nalazi ozljeda ili rana. Tipični klinički znaci generalizirang oblika bolesti su grč muskulature lica, a tijekom progresije bolesti dolazi do generalizirane ukočenosti svih ekstremiteta, intermitentnih toničkih grčeva di

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5

Popoff, Michel R. "Tetanus in animals." Journal of Veterinary Diagnostic Investigation 32, no. 2 (February 18, 2020): 184–91. http://dx.doi.org/10.1177/1040638720906814.

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Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by Clostridium tetani, an environmental soilborne, gram-positive, sporulating bacterium. The disease most often results from wound contamination by soil containing C. tetani spores. Horses, sheep, and humans are highly sensitive to TeNT, whereas cattle, dogs, and cats are more resistant. The diagnosis of tetanus is mainly based on the characteristic clinical signs. Identification of C. tetani at the wound site is often difficult.

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6

B Tongun, Justin, Amanda BB Madison, Joseph D Lako, and Kenneth L Sube. "Neonatal tetanus in South Sudan: a case series." African Health Sciences 24, no. 3 (October 6, 2024): 75–80. http://dx.doi.org/10.4314/ahs.v24i3.11.

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Introduction: Neonatal tetanus is a life-threatening disease of public health importance; it is yet to be eliminated and is still occurring in South Sudan. It is caused by a neurotoxin from a bacterium Clostridium tetani whose spores exist in the environment. Compared to high-income countries, most low-income countries lack intensive care units, and magnesium sulfate shown to improve neonatal tetanus outcomes. Objectives: We aimed to determine the outcome of neonatal tetanus in Al Sabah Children’s Hospital, Juba, South Sudan. Methods: We conducted a case series study in Al Sabah Children’s Hos

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7

Hao, Nguyen Van, Nguyen Ngoc My Huyen, Nguyen Thi Han Ny, Vo Thi Nhu Trang, Nguyen Van Minh Hoang, Duong Bich Thuy, Nguyen Thanh Nguyen, et al. "The Role of the Gastrointestinal Tract in Toxigenic Clostridium tetani Infection: A Case-Control Study." American Journal of Tropical Medicine and Hygiene 105, no. 2 (August 11, 2021): 494–97. http://dx.doi.org/10.4269/ajtmh.21-0146.

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ABSTRACT. Tetanus arises from wound contamination with Clostridium tetani, but approximately one fifth of patients have no discernable entry wound. Clostridium tetani is culturable from animal feces, suggesting the gastrointestinal tract could be an endogenous reservoir or direct-entry portal, but human data are lacking. In this study of 101 Vietnamese adults with tetanus and 29 hospitalized control subjects, admission stool samples were cultured for C. tetani. Anti-tetanus toxin antibodies were measured by ELISA. Clostridium tetani toxigenicity was evaluated using polymerase chain reaction an

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8

Andrade, Luiz Augusto F., and Sonia Maria D. Brucki. "Botulinum toxin A for trismus in cephalic tetanus." Arquivos de Neuro-Psiquiatria 52, no. 3 (September 1994): 410–13. http://dx.doi.org/10.1590/s0004-282x1994000300021.

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Cephalic tetanus is a localized form of tetanus. As in generalized forms , trismus is a prominent feature of the disease, leading to considerable difficulty in feeding, swallowing of the saliva and mouth hygiene. These difficulties often precede respiratory problems and aspiration bronchopneumonia is a frequent life-threatening complication. Muscle relaxants other than curare drugs may show a limited benefit for relieving trismus. Tetanospasmin, the tetanic neurotoxin, and botulinum toxin share many similarities, having a closely related chemical structure, an origin from related microorganism

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9

Düğeroğlu, Harun. "Things to know about tetanus." Ankyra Medical Journal 3, no. 5 (September 30, 2024): 120–23. http://dx.doi.org/10.51271/ankmj-0027.

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Tetanus is a disease of the nervous system characterised by muscle spasms caused by toxins produced by an anaerobic bacterium called Clostridium tetani (C. tetani) found in soil. These muscle spasms may occur frequently in the jaw and neck but may also be generalised throughout the body. The diagnosis can be made clinically and by history. The causative agent of tetanus, C. tetani, produces toxins that trigger muscle contractions after contamination from saliva, faeces, contaminated products and soil. Tetanus is a disease that can be prevented by vaccination. In case of a possible tetanus risk

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10

Möller, Jens, Max Edmund Kraner, and Andreas Burkovski. "More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines." Proteomes 7, no. 2 (April 16, 2019): 15. http://dx.doi.org/10.3390/proteomes7020015.

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Clostridium tetani is the etiological agent of tetanus, a life-threatening bacterial infection. The most efficient protection strategy against tetanus is a vaccination with the C. tetani neurotoxin, which is inactivated by formaldehyde-crosslinking. Since we assumed that besides the tetanus toxin, other proteins of C. tetani may also be present in toxoid preparations, we analyzed commercially available vaccines from different countries in respect to their protein content using mass spectrometry. In total 991 proteins could be identified in all five analyzed vaccines, 206 proteins were common i

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11

Tosun, Selma, Ahmet Deniz Uçar, Ömer Çağlıyan, Alpay Arı, Hülya Özkan Özdemir, and Mehmet Yıldırım. "Investigation of Tetanus Vaccination Status and Tetanus Protection Levels of Cases Admitted with Burns." İzmir Tıp Fakültesi Dergisi 4, no. 1 (March 15, 2025): 3–9. https://doi.org/10.57221/izmirtip.1583544.

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Amaç: Yanık nedeni ile başvuran hastalarda tetanoz aşısı durumunun bilinmesi oldukça önemlidir. Bu çalışmada yanık şikayetiyle başvuran hastaların aşı durumları incelendi. Gereç ve Yöntem: Yanık nedeniyle yanık tedavi merkezine başvuran hastaların tetanoz aşı durumları, ilk sağlık kuruluşunda aşılanma durumları ve serum antitoksin düzeyleri incelendi. Bulgular: Çalışmaya yaşları 24-64 arasında değişen 50'si kadın (%55) olmak üzere toplam 91 hasta dahil edildi. Tetanoz antikorları 15 hastada (%16) kesin negatif, 9 hastada (%10) zayıf pozitifti ve bu hastalar ağırlıklı olarak 40 yaş ve üzerindey

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12

Ali, Rizvan. "Management of Tetanus in Burns: Current Clinical Guidelines in the Emergency Department." Scholars Journal of Applied Medical Sciences 12, no. 05 (May 29, 2024): 682–83. http://dx.doi.org/10.36347/sjams.2024.v12i05.027.

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Tetanus remains a significant concern in patients with burns due to the potential contamination of wounds with Clostridium tetani spores. Prompt and appropriate management in the emergency department (ED) is vital to prevent tetanus-related complications. This article provides a comprehensive overview of the current clinical guidelines for the management of tetanus in burns in the ED setting, emphasizing tetanus vaccination, wound management, tetanus immune globulin (TIG) administration, antibiotic prophylaxis, and monitoring strategies.

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13

B.B.V, Ramanan, Ajit Kumar Pegu, Anupam Dutta, Arjit Das, and Sanchu T. K. Sreeraj. "Cephalic Tetanus without Injury – A Rare Presentation of Tetanus." Journal of Evolution of Medical and Dental Sciences 10, no. 20 (May 17, 2021): 1555–57. http://dx.doi.org/10.14260/jemds/2021/324.

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Tetanus is a rare, severe, and potentially life-threatening disease caused by Clostridium tetani, which accounted 58,900 deaths worldwide in 2013.1 Usually tetanus is generalized, rarely it can be localized also. 20-30% of cases will not have any puncture wound. In this case report, we present a case of tetanus with rare manifestation (localized tetanus presented with trismus without any puncture wound). Multiple rare associations like tetanus presenting with trismus, tetanus occurring in the absence of puncture wound strengthens the need for reporting this case which if left unnoticed would h

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14

Faqih, Fauzan, M. Awalul Rizky Aritiah, Illiyani Solihatin, Fiza Afifah, Hagia Faranajhia, Teguh Budi Wicaksono, and Tomi Irmayanto. "Getting to Know More about Tetanus." PROMOTOR 8, no. 3 (June 2, 2025): 346–51. https://doi.org/10.32832/pro.v8i3.1188.

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Tetanus is an acute disease that affects the central nervous system caused by tetanospasmin toxin produced by Clostridium tetani. Tetanus is a deadly disease in developing countries, killing approximately 500,000 people per year. This is due to lack of hygiene, easy contamination, poor wound care, lack of public awareness of the importance of hygiene and tetanus vaccination. In general, tetanus is characterized by rigidity, muscle spasm and autonomic disorders. Spasms almost always occur in the neck and jaw muscles causing jaw closure (trismus, lockjaw) and involve not only the extremity muscl

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15

Catherine, K., Johny Vakayil Francis, and Sarath Babu. "Successful management of severe tetanus in a 10-year-old unvaccinated girl: A case report." Journal of Pediatric Critical Care 11, no. 2 (2024): 89–91. http://dx.doi.org/10.4103/jpcc.jpcc_79_23.

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Tetanus is a potentially fatal disease caused by Clostridium tetani, which produces muscle spasms, autonomic dysfunction, and respiratory failure by the action of a powerful neurotoxin. Tetanus can be prevented by vaccination, proper wound care, and tetanus prophylaxis, but it remains a significant public health concern in regions with inadequate vaccination coverage. We report a case of severe tetanus in an unvaccinated 10-year-old girl following a tetanus prone injury on her right big toe and was treated with antibiotics, tetanus immunoglobulin, tetanus toxoid, sedatives, neuromuscular block

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16

Pagehgiri, Elma Shari, Dian Kusumastuti Anggraeni Putri, Ni Wayan Nurlina Ekasari, and Bagus Ngurah Mahasena Putera Awatara. "KASUS SERIAL: TETANUS GENERALISATA PADA PASIEN USIA LANJUT." Jurnal Medika Malahayati 8, no. 1 (April 15, 2024): 95–101. http://dx.doi.org/10.33024/jmm.v8i1.12725.

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Abstrak: Kasus Serial: Tetanus Generalisata Pada Pasien Usia Lanjut. Tetanus merupakan penyakit infeksi yang dapat dicegah dengan vaksin dan mengancam jiwa di negara berkembang. Infeksi ini disebabkan oleh neurotoksin yang dihasilkan oleh Clostridium tetani. Kami memaparkan tiga kasus tetanus generalisata yang masuk RSD Mangusada selama Juli 2023. Ketiga kasus tersebut merupakan tetanus generalisata pada lansia yang tidak memiliki status imunisasi. Semua pasien telah menerima terapi yang memadai dengan antitoksin, antibiotik, dan perawatan suportif. Dari 3 kasus tersebut, 1 pasien menunjukan p

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17

Noor, Nawsabah, Homayra Tahseen Hossain, Mohammad Mohsin, Mahbub Mayukh Rishad, and Mohammad Zahiruddin. "If the Mind Doesn’t Know, the Eyes cannot See: A Case report of Localized Tetanus." Bangladesh Journal of Medicine 34, no. 2 (April 30, 2023): 168–70. http://dx.doi.org/10.3329/bjm.v34i2.65556.

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Tetanus is a vaccine-preventable disease caused by a potent neurotoxin released by an obligate anaerobic bacterium, Clostridium tetani infection. Presentations of tetanus include generalized tetanus, neonatal tetanus, cephalic tetanus, and localized tetanus, the latter two being much rarer. This is a case report of localized tetanus involving the facial muscle in the form of lock jaw in 63-year inadequately immunized gentleman following an unhygienic tooth extraction from rural area. The condition deteriorated further, and the patient was under ventilatory support for 3days. The patient had an

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18

Selim, A. M., E. M. Ibrahim, Meshad El, and F. K. Hamouda. "Development of IgY antibodies for control of tetanus." Biotehnologija u stocarstvu 31, no. 1 (2015): 109–22. http://dx.doi.org/10.2298/bah1501109s.

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Tetanus is a cut and often highly fatal infectious disease that affects both human and animals; the disease caused by exotoxin which produced by C. tetani. In the current study, we try to get hyperimmune IgY in chicken egg against tetanus toxin and use it as prophylaxis and therapeutic treatment for tetanus. The obtained IgY titer after inoculation of tetanus toxin in chicken eggs was 1320 limit of flocculation (Lf-eq) after 72 hr. IgY in adose of 4500 Lf-eq can be protect donkey after artificial infection by 1 minimum lethal dose (MLD) of C. tetani. While a dose of 30000 Lf-eq IgY intramuscul

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Chawla, Dr Anil Kumar, Chandrani Das, Paramdeep Singh, Mansha Tiwari, and Dr Seema Chaudhary. "Production of tetanus toxin by using media substantially free from meat and blood." Asian Journal of Pharmaceutical and Clinical Research 9, no. 6 (November 1, 2016): 284. http://dx.doi.org/10.22159/ajpcr.2016.v9i6.14410.

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The present study was to redesign the conventional Mueller and Miller medium to produce tetanus toxin from Clostridium tetani. Meat based ingredients (such as Bovine Heart/ Brain/ Liver Infusion) were replaced with vegetable peptone & alternate casein hydrolysate and scaled up from 100mL to 1000mL. Modified Mueller and Miller Medium containing vegetable peptone (substitute of BHI) and alternate casein hydrolysate were used for production and scale -up of tetanus toxin. Detoxification of tetanus toxin was carried out by using formaldehyde to produce tetanus toxoid. Purification of tetanus t

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20

Celichowski, J. "Tetanic depression: a phenomenon influencing the production of tension in fast-twitch motor units in rat medial gastrocnemius." Acta Neurobiologiae Experimentalis 61, no. 2 (June 30, 2001): 119–23. http://dx.doi.org/10.55782/ane-2001-1392.

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The influence of an increase or a decrease in the stimulation frequency on tension development during a tetanus was studied in motor units of the rat medial gastrocnemius muscle. These effects were tested in one tetanus evoked at two frequencies of stimulation, a lower immediately followed by a higher one or the reverse. For all fast motor units it was observed that after the first part of a tetanus at a lower frequency of stimulation the tension of the following part, of the better fused contraction, was depressed. This effect was called a tetanic depression. When the lower stimulation freque

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21

Lai, Xiaofei, Felycia Fernanda Hosyanto, and Lei Xu. "Risk of Clostridium tetani infection in an elderly patient following hemorrhoid ligation." Journal of International Medical Research 48, no. 10 (October 2020): 030006052096398. http://dx.doi.org/10.1177/0300060520963983.

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Tetanus after gastrointestinal surgery is an extremely rare but very dangerous disease caused by infection with Clostridium tetani. Tetanus can occur due to bacterial infection during surgery or dressing change, or the bacteria may exist in the patient’s intestines and be discharged with feces. This report describes a 71-year-old woman who developed tetanus 3 days after a hemorrhoidal ligation. Clinicians need to be aware of symptoms of C. tetani infection that might present in patients who have undergone gastrointestinal procedures.

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22

Seo, Seung Won, Jaewon Lee, Bong-Goo Yoo, Jehun Kim, and So-Young Huh. "Autonomic instability in severe tetanus: a case report." Annals of Clinical Neurophysiology 23, no. 2 (October 29, 2021): 117–20. http://dx.doi.org/10.14253/acn.2021.23.2.117.

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Tetanus is an infectious disease of the nervous system caused by Clostridium tetani, and is characterized by tonic muscle contractions, painful spasms, and autonomic dysfunction. Severe autonomic dysfunction associated with tetanus can be life-threatening. We present a 62-year-old female who experienced lockjaw after an ankle fracture. The patient was diagnosed with tetanus and received tetanus immunoglobulin and a vaccination. The patient subsequently experienced labile hypertension. This case highlights the challenge and importance of managing cardiovascular instability.

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Pouillon, JM, and BD Caldwell. "The risk of tetanus in podiatric medicine." Journal of the American Podiatric Medical Association 88, no. 7 (July 1, 1998): 349–52. http://dx.doi.org/10.7547/87507315-88-7-349.

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Although tetanus is a preventable disease, several cases are reported to the Centers for Disease Control and Prevention each year. Many conditions treated by podiatric physicians carry the risk of infection by Clostridium tetani, and it is advisable for podiatrists to update a patient's tetanus immunization status if the patient presents with a tetanus-prone wound.

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Barclay, C. J. "Effect of fatigue on rate of isometric force development in mouse fast- and slow-twitch muscles." American Journal of Physiology-Cell Physiology 263, no. 5 (November 1, 1992): C1065—C1072. http://dx.doi.org/10.1152/ajpcell.1992.263.5.c1065.

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Changes in the rate of isometric force development with fatigue were measured in vitro (25 degrees C) using mouse soleus and extensor digitorum longus (EDL) muscles. Muscles were fatigued using 30 tetanic contractions. Rate of force development was determined from the rate constant of an exponential curve fitted to the rising force phase of a tetanus. For both muscles, when the intertetanus interval was 3 s, maximum isometric force and relaxation rate were significantly reduced in the final tetanus relative to the values in the first tetanus. Rate of force development in soleus muscles transie

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Hirka, E. I., and M. S. Popov. "IMMUNOLOGICAL EFFICIENCY OF THE TETANUS TOXOID USE FOR THE URGENT SPECIFIC TETANUS PREVENTION IN PATIENTS WITH THE WOUND INFECTION." Kharkiv Surgical School, no. 3 (March 20, 2020): 54–57. http://dx.doi.org/10.37699/2308-7005.3.2020.11.

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Summary. Aim. The present study aimed to analyze the effectiveness of tetanus toxoid administration during the urgent specific tetanus prevention. Materials and methods. The determination of tetanus immunity levels in patients with the wound infection before immunization, then 2 and 4 weeks after vaccination. Studies of blood sera of patients were carried out in dynamics by enzyme-linked immunosorbent assay using a set of test systems for determining IgG antibodies to tetanus toxoid «Clostridium tetani toxin IgG», ELISA, Nova Tec Immundiagnostica GmbH, Germany. Results of the study were

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Simovanyan, E. M., E. L. Goncharova, and V. B. Denisenko. "Tetanus is a difficult diagnosis in children." CHILDREN INFECTIONS 18, no. 4 (December 6, 2019): 70–72. http://dx.doi.org/10.22627/2072-8107-2019-18-4-70-72.

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The sporadic incidence of tetanus, the identity of symptoms with the clinical picture of a number of common neuroinfections, the high frequency of various background pathologies create difficulties in disease diagnosing in children. On the case history example of a 3 years 9 months old child with two diseases (tetanus, enterovirus infection) that developed against the background of the active form of herpesvirus infection, an algorithm of diagnostic and therapeutic measures is presented.A differential diagnosis was made between the generalized form of tetanus and meningoencephalitis of enterov

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Ahmed, Hafizuddin. "Tetanus Following Root Canal Surgery." KYAMC Journal 3, no. 1 (February 5, 2013): 265–68. http://dx.doi.org/10.3329/kyamcj.v3i1.13663.

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2400 years ago Hippocrates recognised Tetanus as a dreadful disease.It is caused by a straight slender gram positive anaerobic rod-Clostridium Tetani, the toxin of which interferes with acetylecholine/cholinesterase balance at peripheral motor end plate of central nervous system causing sustained tonic spasm. Children are routinely immunized these days everywhere against Diptheria,Pertisis,Tetanus,Poliomyelitis etc.But this does not apply with aged people who were not routinely immunized during their infancy making them vulnerable to these diseases including Tetanus. Majority of Tetanus cases

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Ishraq Ahmed Chiad and Ban Yousif Yaaqoob. "Pregnant women’s knowledge of Tetanus disease and immunization against Tetanus disease in the City of Baghdad." Journal of the Pakistan Medical Association 73, no. 9 (October 6, 2023): S36—S39. http://dx.doi.org/10.47391/jpma.iq-07.

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Objective: To estimate the understanding of tetanus and tetanus toxoid injections among pregnant women.Method: The cross-sectional study was conducted at the Baghdad General Hospital and a primary healthcare centrein Bab-Almuadham, Iraq, from November 15, 2020, to January 15, 2021, and comprised 100 pregnant women aged15-45 years. Data was gathered through face-to-face structured interviews using a complete self-assessmentquestionnaire. Data was analysed using SPSS 27.Results: Of the 100 women with mean age of 28.4±10.6 years (range: 15-44 years), 27(27%) were aged 20-24 years,70(70%) were fro

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ALTRINGHAM, J. D., and I. A. JOHNSTON. "Activation of Multiply Innervated Fast and Slow Myotomal Muscle Fibres of the Teleost Myoxocephalus Scorpius." Journal of Experimental Biology 140, no. 1 (November 1, 1988): 313–24. http://dx.doi.org/10.1242/jeb.140.1.313.

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A nerve-muscle preparation from the sculpin Myoxocephalus scorpius was used to study the membrane response of fast and slow muscle fibres to stimulation of the spinal nerves. There was no significant difference between resting potential in fast (−81.9mV) and slow fibres (−80.8mV). Fast fibres responded to a suprathreshold stimulus in the spinal nerve with an action potential. Overshoots of up to +32 mV were recorded. Both junction potentials and overshooting action potentials were observed in the slow fibres. The twitch/tetanus characteristics of myotomal muscle were investigated using isolate

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Taribuka, Netty, and Mirna Heluth. "Penyuluhan Tentang Suntik Tetanus Toksoid Kepada Ibu Hamil Primigravida Di Pesisir Loun." Jurnal Pengabmas Masyarakat Sehat (JPMS) 1, no. 4 (October 30, 2019): 256–60. http://dx.doi.org/10.33992/ms.v1i4.1362.

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In 2008 there were cases of Tetanus Neonatorum with 91 cases of death or a Case Fatality Rate (CFR) of 55%. Most of the cases of Tetanus Neonatorum were babies whose deliveries were assisted by traditional birth attendants. Tetanus neonatorum is a tetanus disease that occurs in neonates (infants less than 1 month old) caused by Clostridium tetani, which is a germ that releases toxins that attack central nervous system. Risk factors that cause neonatal tetanus are delivery that does not meet cleanliness, namely umbilical cord care does not meet health requirements and administration of Tetanus

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Tejaya, Novi, and Marina Musyawwirina Desiprimayanti Ruslan Ramli. "Generalized Tetanus in A Patient with Infected Sutured Wound: A Case Report." AKSONA 3, no. 1 (January 31, 2023): 13–19. http://dx.doi.org/10.20473/aksona.v3i1.37362.

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Highlight: Tetanus in patients with infected sutured wound. Complications of death in generalized tetanus. The importance of education about tetanus. ABSTRACT Introduction: Tetanus is a disease caused by Clostridium tetani, which produces an exotoxin. Tetanus can rapidly progress into life-threatening muscle spasms accompanied by respiratory insufficiency with or without autonomic dysfunction. Case: A 43-year-old male patient was referred from the public health center to Tora Belo Hospital with mouth stiffness and difficulty swallowing food. He also had stiffness and pain in the neck, abdomen,

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Listyono Putro, Jati Febriyanto Adi, Andy Nugroho, Septian Adi Permana, and Andi Hermawan. "Successful Management of Grade III Tetanus with Therapeutic Plasma Exchange: A Case Report." Journal of Anesthesiology and Clinical Research 5, no. 3 (September 20, 2024): 706–18. http://dx.doi.org/10.37275/jacr.v5i3.644.

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Introduction: Tetanus, a severe neurologic disorder caused by Clostridium tetani neurotoxin, presents with progressive muscle rigidity and spasms. Grade III tetanus, characterized by generalized tetanus with severe spasms, carries a high mortality risk. Therapeutic plasma exchange (TPE) has emerged as an adjunctive therapy to remove circulating toxins and inflammatory mediators. Case presentation: We report a 50-year-old male with grade III tetanus following a minor injury. Despite standard treatment with tetanus immunoglobulin, antibiotics, and muscle relaxants, his condition deteriorated, ne

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Moniuszko, Anna, Agata Zajkowska, Ewa Tumiel, Krzysztof Rutkowski, Piotr Czupryna, Sławomir Pancewicz, Ryszard Rutkowski, Agnieszka Zdrodowska, and Joanna Zajkowska. "Meningitis, Clinical Presentation of Tetanus." Case Reports in Infectious Diseases 2015 (2015): 1–2. http://dx.doi.org/10.1155/2015/372375.

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Background. Tetanus is an acute disease caused by a neurotoxin produced byClostridium tetani. Tetanus immunization has been available since the late 1930s but sporadic cases still occur, usually in incompletely vaccinated or unvaccinated individuals.Case Report. An elderly previously vaccinated female contracted tetanus following foot injury. Clinically she presented with meningitis causing diagnostic and therapeutic delays.Why Should Physician Be Aware of This?Even in developed countries the differential diagnosis of meningitis, especially in the elderly, should include tetanus. Treatment in

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van den Bosch, W. J. H. M. "Tetanus, nieuwe richtlijnentetanus tetanus, richtlijnen tetanus, vaccinatie tetanus, booster tetanus, TIG." Bijblijven 19, no. 10 (October 2003): 400–402. http://dx.doi.org/10.1007/bf03059743.

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Bernal, O. R. Aguilar, M. A. Bender, and ME Lacy. "Efficacy of Dantrolene Sodium in Management of Tetanus in Children." Journal of the Royal Society of Medicine 79, no. 5 (May 1986): 277–81. http://dx.doi.org/10.1177/014107688607900507.

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The effectiveness of dantrolene sodium in controlling tetanic spasms was evaluated in 21 children (aged 4 days-13 years) with tetanus. These dantrolene-treated patients were compared with an historical control group of 26 children previously treated for tetanus by traditional means at the same institution. The groups were comparable in terms of age, other treatments, and severity of disease. All patients received standard treatments for tetanus, including sedatives, antibiotics, and tetanus-immune globulin. Patients in the dantrolene-treated group also received dantrolene, either intravenously

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Prasanty, Cindy Aprilia Eka, Gianina Angelia Santoso, and Nikmatul Choiriyah. "FROM TOOTH TO TETANUS: A CASE REPORT ON TETANUS FOLLOWING AN ODONTOGENIC INFECTION." JPHV (Journal of Pain, Vertigo and Headache) 5, no. 2 (September 1, 2024): 43–46. https://doi.org/10.21776/ub.jphv.2024.005.02.05.

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Tetanus is an infectious nervous system disease characterized by increased muscle tone, caused by the toxin of the bacterium Clostridium tetani (C. tetani). Tetanus infection generally starts from contaminated open wounds. However,we have found an unexpected consequence of tetanus with odontogenic infection as a potential port of entry. A sixty-year-old male patient with a cavity in the second molar of the lower right region complained of weakness and fever since one day before admission to the hospital. The patient's tetanus immunization status was unknown. On the first day of treatment, the

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Gobbur, R. H., P. Jagruthi, Anilkumar Sajjan, and S. S. Kalyanshettar. "An unusual cause for neck rigidity?" IP International Journal of Medical Paediatrics and Oncology 7, no. 3 (October 15, 2021): 161–63. http://dx.doi.org/10.18231/j.ijmpo.2021.031.

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Otogenic tetanus is a subtype of cephalic tetanus, limited to the head & neck, but can progress to a more generalized form. Caused by the spore-forming bacillus, Clostridium tetani, It produces a potent toxin, tetanospasmin, preventing inhibitory neurotransmitters' release, hence causing rigidity.

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Chua, Michael, and Angela F. Dulhunty. "Diazepam reveals different rate-limiting processes in rat skeletal muscle contraction." Canadian Journal of Physiology and Pharmacology 65, no. 2 (February 1, 1987): 272–73. http://dx.doi.org/10.1139/y87-048.

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The action of the tranquilizer diazepam on rat skeletal muscle showed that relaxation of isometric twitches is controlled by different processes in extensor digitorum longus (fast-twitch) and soleus (slow-twitch) muscles. Diazepam caused an increase in the amplitude of twitches in fibres from both muscles but increased the twitch duration only in soleus. The amplitude of fused tetani were reduced in both muscles and the rate of relaxation after the tetanus slowed by as much as 34% when the amplitude of the tetanus was reduced by only 11%. The slower tetanic relaxation indicated that calcium up

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Sunarsih, Sunarsih, Ana Mariza, Fijri Rachmawati, and Putu Candrawati. "Edukasi Imunisasi TT (Tetanus Toxoid) pada Calon Pengantin." JURNAL KREATIVITAS PENGABDIAN KEPADA MASYARAKAT (PKM) 5, no. 7 (July 1, 2022): 2238–42. http://dx.doi.org/10.33024/jkpm.v5i7.6305.

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ABSTRAK Pemeriksaan kesehatan pranikah lebih memfokuskan pada kesehatan reproduksi. Salah satu bentuk pemeriksaan yang juga merupakan syarat yang harus dipenuhi adalah imunisasi Tetanus Toxoid yang bertujuan untuk mencegah tetanus neonatorum. Penyakit tetanus neonatorum adalah penyakit tetanus yang terjadi pada neonatus (bayi berusia kurang 1 bulan). Angka kematian kasus (Case Fatality Rate) sangat tinggi. Pada kasus tetanus neonatorum yang tidak dirawat, angkanya mendekati 100%, terutama yang mempunyai masa inkubasi kurang dari 7 hari. Tujuan edukasi adalah untuk meningkatkan pengetahuan masa

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Guyennet, Eloïse, Jean-Laurent Guyomard, Emilie Barnay, Franck Jegoux, and Jean-François Charlin. "Cephalic Tetanus from Penetrating Orbital Wound." Case Reports in Medicine 2009 (2009): 1–3. http://dx.doi.org/10.1155/2009/548343.

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Tetanus is a neurologic disorder caused by tetanospasmin, a protein toxin elaborated by Clostridium tetani. Cephalic tetanus is a localized form of the disease causing trismus and dysfunction of cranial nerves. We report the case of a man who presented with facial trauma, complete ophthalmoplegia, exophthalmos, areactive mydriasis, and periorbital hematoma. An orbital CT revealed air bubbles in the right orbital apex. The patient was given a tetanus toxoid booster and antibiotherapy. After extraction of a wooden foreign body, the patient developed right facial nerve palsy, disorders of swallow

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Chaudhary, Raina, Binod Karki, Sabita Bhatta, and Manoj Pradhan. "Localized Tetanus: Rare and Elusive." Medical Journal of Shree Birendra Hospital 12, no. 1 (November 4, 2013): 47–49. http://dx.doi.org/10.3126/mjsbh.v12i1.9095.

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Tetanus is acute and fatal infectious disease which is acquired due to contamination of wound with soil or animal feces containing spores of Clostridium tetani. In this case, 24 old male, serving personnel of Nepalese Army, developed localized tetanus, a rare form of tetanus nearly 3 weeks following crocodile bite in his left thigh. It was painful with involvement of only local flexor muscles at the site of injury. The aim is to incite awareness of the rare form of the Tetanus in adult which is often overlooked in clinical practice.Medical Journal of Shree Birendra Hospital; January-June 2013/

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Eric, SHINGIRO, Luck MWIZERWA Jean, and HAKIZIMANA David. "Thoracic Spine Deformity Post Tetanus: A Case Report of Tetanus Post Circumcision." International Journal Of Medical Science And Clinical Research Studies 02, no. 10 (October 17, 2022): 1073–77. https://doi.org/10.5281/zenodo.7215135.

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Tetanus is caused by clostridium tetani bacteria through skin breach. The tetanus is characterized by tonic contraction and muscle spasm which can cause vertebral fracture in some patients.   we are reporting a young male patient who after ring circumcision technique had tetanus complicated into thoracic vertebral fracture with severe kyphotic deformity and lower limb functional impairment.   The surgical management was performed in two stages: First stage consisted of Shwab 2 osteotomy, pedicle screws and rod fixation with good result for deformity correction.   The second stag

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PETER, SAIKALI, SEQUEIRA HERMAN, WINTER STEPHEN, and SHUMBAIRERWA SAMSON. "TETANUS FROM WOUND CONTAMINATION BY ELEPHANT DUNG: A CASE REPORT AND REVIEW OF THE RECOGNITION AND EVIDENCE-BASED MANAGEMENT OF ACUTE TETANUS INFECTION." Journal of Medicine and Health Research 3, no. 1 (January 26, 2018): 1–7. https://doi.org/10.5281/zenodo.1412250.

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Tetanus, a vaccine-preventable neuroinvasive disease, is caused by <em>Clostridium tetani</em>. Although incidence rates in the western world have decreased drastically when compared with developing nations, these numbers will be on the rise given the increasing immigration rates to developed countries, as seen in recent outbreaks of several other vaccine-preventable diseases in the United States of America. This article highlights a case of a Zimbabwean man with an unexpected method of <em>C. tetani</em> inoculation through application of elephant dung on a malignant foot lesion, and the need

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Malinovská, Z., E. Čonková, and P. Váczi. "Tetanus in Animals — Summary of Knowledge." Folia Veterinaria 64, no. 3 (September 1, 2020): 54–60. http://dx.doi.org/10.2478/fv-2020-0027.

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AbstractTetanus is a neurologic non-transmissible disease (often fatal) of humans and other animals with a worldwide occurrence. Clostridium tetani is the spore producing bacillus which causes the bacterial disease. In deep penetrating wounds the spores germinate and produce a toxin called tetanospasmin. The main characteristic sign of tetanus is a spastic paralysis. A diagnosis is usually based on the clinical signs because the detection in the wound and the cultivation of C. tetani is very difficult. Between animal species there is considerable variability in the susceptibility to the bacill

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Dr, Sahibzada Aneesullah Muhammad Fayaz Dr Ghulam Murtaza Ali. "A COMPREHENSIVE STUDY ON RISK FACTORS, VACCINATION STATUS AND OUTCOME OF TETANUS IN CHILDREN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 06 (May 31, 2019): 11243–45. https://doi.org/10.5281/zenodo.3236376.

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<strong><em>Introduction: </em></strong><em>Tetanus is an acute neurological but vaccine-preventable disease caused by <em>Clostridium tetani</em> that causes significant morbidity and mortality among children in developing countries. <strong>Aims and objectives: </strong>The basic purpose of the study is to analyse the study on risk factors, vaccination status and outcome of tetanus in children.<strong> Methodology of the study: </strong>This cross sectional study was conducted in PIMS, Islamabad during March 2018 to January 2019. The data was collected from 100 children of both gen

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Dr, Sahibzada Aneesullah Muhammad Fayaz Dr Ghulam Murtaza Ali. "A COMPREHENSIVE STUDY ON RISK FACTORS, VACCINATION STATUS AND OUTCOME OF TETANUS IN CHILDREN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 06 (May 26, 2019): 11246–48. https://doi.org/10.5281/zenodo.3376610.

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<strong><em>Introduction: </em></strong><em>Tetanus is an acute neurological but vaccine-preventable disease caused by <em>Clostridium tetani</em> that causes significant morbidity and mortality among children in developing countries. <strong>Aims and objectives: </strong>The basic purpose of the study is to analyse the study on risk factors, vaccination status and outcome of tetanus in children.<strong> Methodology of the study: </strong>This cross sectional study was conducted in PIMS, Islamabad during March 2018 to January 2019. The data was collected from 100 children of both gen

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Wulandari, Annisa, Purwaningsih Purwaningsih, and Astuti Rofida. "PENDIDIKAN KESEHATAN PADA IBU HAMIL MELALUI PEMBERIAN IMUNISASI TT (TETANUS TOKSOID) DI WILAYAH KERJA UPT. PUSKESMAS PULO BRAYAN." SENTRI: Jurnal Riset Ilmiah 3, no. 1 (January 15, 2024): 442–54. http://dx.doi.org/10.55681/sentri.v3i1.2198.

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Imunisasi tetanus toksoid merupakan suatu cara untuk menimbulkan/meningkatkan kekebalan seseorang secara aktif terhadap infeksi Tetanus saat atau pasca persalinan. Tetanus yaitu gangguan neurologis yang ditandai dengan meningkatnya tonus otot dan spasme, yang disebabkan oleh Clostridum Tetani. Salah satu pencegahan Tetanus Neonatrum adalah dengan melakukan Imunisasi Tetanus Toksoid pada Ibu Hamil. Tujuan dari penelitian ini adalah memberi gambaran Pendidikan Kesehatan Pada Ibu hamil melalui pemberian imunisasi Tetanus Toksoid (TT). Metodeologi : Penelitian ini menggunakan metode deskriptif mel

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He, Qing, Yejian Wu, Shuiping Hou, Lei Luo, and Zhoubin Zhang. "Seroprevalence of Diphtheria and Tetanus Immunoglobulin G among the General Health Population in Guangzhou, China." Vaccines 12, no. 4 (April 4, 2024): 381. http://dx.doi.org/10.3390/vaccines12040381.

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A seroepidemiological study was conducted in 2018 to assess diphtheria and tetanus antibodies in Guangzhou, China. Diphtheria and tetanus antibody concentrations were measured with an enzyme-linked immunosorbent assay. A total of 715 subjects were enrolled in the study. The overall diphtheria and tetanus toxoid IgG-specific antibody levels were 0.126 IU/mL (95% CI: 0.115, 0.137) and 0.210 IU/mL (95% CI: 0.185, 0.240), respectively; the overall positivity rate was 61.82% (95% CI: 58.14, 65.39) and 71.61% (95% CI: 68.3, 74.92), respectively. The diphtheria and tetanus antibody concentration was

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Khadka, Bikash, Kishor Khanal, and Nisha Sharma. "Persistent Pyrexia in Tetanus: A Case Report from Nepal." Birat Journal of Health Sciences 7, no. 3 (December 31, 2022): 1919–20. http://dx.doi.org/10.3126/bjhs.v7i3.52774.

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Tetanus, an infection caused by the gram-positive, obligate anaerobic bacillus Clostridium tetani, is still prevalent in developing countries. Fever is an unusual symptom in tetanus. The disease must be managed by preventing tetanospasmin absorption, treating symptoms, stabilizing autonomic instability, using antibiotics, and controlling the airway with assisted ventilation if necessary. We present a case report of a tetanus patient who had persistent pyrexia despite ruling out all the obvious causes of fever ,that coincide with the persistence of muscle spasms and/or use of prolonged duration

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Mayousse, Vincent, Caroline Soete, and Aurélien Jeandel. "Suspected Generalized Neonatal Tetanus in a Litter of Puppies." Journal of the American Animal Hospital Association 59, no. 1 (December 30, 2022): 51–55. http://dx.doi.org/10.5326/jaaha-ms-7246.

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ABSTRACT Tetanus, caused by Clostridium tetani neurotoxin, is extensively described in adult dogs and is frequently associated with a recent history of wounds. Although this condition is reported in 2–3 mo old puppies, tetanus has not been described in neonates. Herein, we report the clinical signs of 3–5 day old American Bully puppies from the same litter, presenting with an acute onset of marked generalized stiffness of the extensor muscles, trismus, and an inability to suckle. Three puppies died because of tetanus: one died during consultation, one was euthanized owing to respiratory distre

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