Relevant bibliographies by topics / Tetrahydropyridine derivatives

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Tetrahydropyridine derivatives'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Tetrahydropyridine derivatives"

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W. Ardley, Tiffany. "The Chemistry and Pharmacology of Tetrahydropyridines: Part 2." Clinical Medical Reviews and Reports 5, no. 01 (2023): 01–16. https://doi.org/10.31579/2690-8794/135.

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Tetrahydropyridines (THPs) have sparked notable interest as an auspicious heterocyclic moiety. Existing in distinct structural isomers including 1,2,3,4-tetrahydropyridine, 1,2,3,6-tetrahydropyridine, 2,3,4,5-tetrahydropyridine, its presence has been identified in both natural products and synthetic pharmaceutical agents. Many THP-containing compounds have been synthesized by the inspiration of known bioactive natural products and have been found to possess biologically active properties. For this reason, more innovative methods have been developed for the synthesis of substituted-tetrahydropy
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Šilhánková, Alexandra, Dagmar Davidová, Michaela Šputová, et al. "Photoaddition of alcohols to some 1,2,3,6-tetrahydropyridines." Collection of Czechoslovak Chemical Communications 52, no. 5 (1987): 1298–304. http://dx.doi.org/10.1135/cccc19871298.

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Photochemical addition of methanol to 1,2,3,6-tetrahydropyridine derivatives Ia, Ib, Id-Ii and III afforded methoxypiperidines IIa-IIg and IV as Markovnikov type addition products. Reduction of 4-methyl-1-(2-propenyl)pyridinium bromide with sodium borohydride yielded 4-methyl-1-(2-propenyl)-1,2,3,6-tetrahydropyridine (Ig).
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Li, Jun, Xiaochen Chi, Long Meng, et al. "Palladium-catalyzed heck-type cascade cyclization of (Z)-1-iodo-1,6-dienes with N-tosyl hydrazones." Organic & Biomolecular Chemistry 16, no. 40 (2018): 7356–60. http://dx.doi.org/10.1039/c8ob01821a.

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Berti, Francesco, Federico Malossi, Fabio Marchetti, and Mauro Pineschi. "A highly enantioselective Mannich reaction of aldehydes with cyclic N-acyliminium ions by synergistic catalysis." Chemical Communications 51, no. 71 (2015): 13694–97. http://dx.doi.org/10.1039/c5cc04416b.

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A novel enantioselective synthesis of carbamoyl isoquinoline and tetrahydropyridine derivatives is accomplished using matched combinations of Lewis or Brønsted acids and secondary amine organocatalysts.
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Jahanshahi, R., and B. Akhlaghinia. "Cu(ii)-grafted SBA-15 functionalized S-methylisothiourea aminated epibromohydrin (SBA-15/E-SMTU-CuII): a novel and efficient heterogeneous mesoporous catalyst." New Journal of Chemistry 41, no. 15 (2017): 7203–19. http://dx.doi.org/10.1039/c7nj00849j.

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Jiang, Yu, Xiang-Ying Tang, and Min Shi. "A Rh-catalyzed 1,2-sulfur migration/aza-Diels–Alder cascade initiated by aza-vinyl carbenoids from sulfur-tethered N-sulfonyl-1,2,3-triazoles." Chemical Communications 51, no. 11 (2015): 2122–25. http://dx.doi.org/10.1039/c4cc08829h.

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A novel Rh(ii) catalyzed intramolecular 1,2-sulfur migration/intermolecular aza-Diels–Alder cascade of sulfur-tethered N-sulfonyl-1,2,3-triazoles has been developed, efficiently affording sulfur-containing tetrahydropyridine derivatives.
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Zhu, Yu-Jie, Xiao-Feng Guo, Zhi-Jin Fan, et al. "Approach to thiazole-containing tetrahydropyridines via Aza–Rauhut–Currier reaction and their potent fungicidal and insecticidal activity." RSC Advances 6, no. 113 (2016): 112704–11. http://dx.doi.org/10.1039/c6ra24342h.

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Insecticidal and fungicidal active thiazole-containing tetrahydropyridine derivatives with accurately predicted 3D QSAR model againstAphis LaburniKaltenbach and predicted potential anti-fungus target of fumarate reductase without cross resistance were synthesized.
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Shakurova, Elvira R., and Lyudmila V. Parfenova. "Synthesis of N-Heterocyclic Analogues of 28-O-Methyl Betulinate, and Their Antibacterial and Antifungal Properties." Molbank 2020, no. 1 (2019): M1100. http://dx.doi.org/10.3390/m1100.

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The paper presents the results on the one-pot pyridine quaternization using betulinic 28-O-methyl ester (1) and Tempo+Br3− cation followed by reduction of the resulting salt (2) to 1,2,5,6-tetrahydropyridine derivative (3). The structures of new compounds are confirmed by means of 1D and 2D-NMR spectroscopy, as well as MALDI TOF/TOF spectrometry. The derivatives 2 and 3 are active against S. aureus at the minimum inhibitory concentration (MIC) of 4 μg/mL and 16 μg/mL, correspondingly.
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Ivanova, Evgeniya V., Nikolay N. Zhukov, Irina I. Surova, Maria B. Nikishina, Loik G. Mukhtorov, and Yuri M. Atroshchenko. "STUDY OF THE EFFECT OF NEW 6-R-3,5-DINITRO-1,2,3,4-TETRAHYDROPYRIDINES ON THE ACCUMULATION OF PHOTOSYNTHETIC PIGMENTS AND ASCORBIC ACID IN PLANT TISSUES." Siberian Journal of Life Sciences and Agriculture 14, no. 6 (2022): 372–87. http://dx.doi.org/10.12731/2658-6649-2022-14-6-372-387.

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Background. The problem of finding new effective plant protection products remains an urgent task of modern agrochemistry. It is known that tetrahydropyridine derivatives exhibit a broad spectrum of biological activity, including fungicidal activity. However, compounds with potential biological activity can also be highly toxic to humans, cultivated crops, and the environment as a whole, so it is necessary to study their environmental safety. The content of photosynthetic pigments and ascorbic acid are one of the most important biochemical indicators of plant response to environmental stress f
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Gizur, T., B. Kiss, K. Harsányi, et al. "Novel 1,2,3,6-tetrahydropyridine derivatives with potent antihypoxic activity." European Journal of Medicinal Chemistry 29, no. 5 (1994): 349–55. http://dx.doi.org/10.1016/0223-5234(94)90059-0.

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Dissertations / Theses on the topic "Tetrahydropyridine derivatives"

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Anderson, Andrea H. "Mechanistic Studies on the Monoamine Oxidase B Catalyzed Oxidation of 1,4-Disubstituted Tetrahydropyridine Derivatives." Diss., Virginia Tech, 1997. http://hdl.handle.net/10919/30566.

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The flavin-containing monoamine oxidases (MAO) A and B catalyze the oxidative deamination of primary and secondary amines. The overall process involves a two electron oxidation of the amine to the iminium with concomitantreduction of the flavin. Based on extensive studies with a variety of chemical probes, Silverman and colleagues have proposed a catalytic pathway for the processing of amine substrates and inactivators by MAO-B that is initiated by a single electron transfer (SET) step from the nitrogen lone pair to the oxidized flavin followed by a-proton loss from the resulting amine radica
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McNaught, Kevin St Patrick. "The neurotoxic potential of isoquinoline derivatives structurally related to the Parkinsonism-inducing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321681.

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Shang, Xueqin. "Metabolic Studies on 1-Cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridinyl Derivatives by HPLC and LC-ESI/MS." Thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/9790.

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The MAO-B catalyzed metabolic bioactivation of the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to generate the neurotoxic 1-methyl-4-phenylpyridinium species (MPP+) is well documented. The N-cyclopropyl analog (CPTP) of MPTP is a mechanism based inactivator of MAO-B which presumably is processed by a single electron transfer (SET) pathway to generate a bioalkylating species. These results have prompted us to study how the cytochromes P450, the major liver drug metabolizing oxidases, interact with N-cyclopropyl analogs of MPTP. HPLC with diode array detection
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Isin, Emre Mehmet. "Studies on the Synthesis and Rearrangement of Indazolylpyridinium Derivatives Precursors to Potential Neuroprotective Prodrugs Bearing a 1,2,3,6-Tetrahydropyridinyl Carrier." Diss., Virginia Tech, 2004. http://hdl.handle.net/10919/27363.

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The neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazole (7-NI) protects against the neurotoxicity of MPTP in a mouse model of neurodegeneration. Since 7-NI also inhibits the monoamine oxidase-B (MAO-B) catalyzed bioactivation of MPTP, the role of nNOS inhibition as a mediator of 7-NI's neuroprotective properties have been challenged. In order to examine in greater detail the neuroprotective effects of indazolyl derivatives, the synthesis of water soluble indazolyltetrahydropyridinyl derivatives as potential "prodrugs" that may undergo MAO bioactivation in the brain was undertaken.
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Book chapters on the topic "Tetrahydropyridine derivatives"

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Satow, Jun, Kenzou Fukuda, Kaoru Itoh, and Tsutomu Nawamaki. "Tetrahydropyridazine Derivatives." In ACS Symposium Series. American Chemical Society, 1995. http://dx.doi.org/10.1021/bk-1995-0584.ch010.

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Sullivan, J. P., and K. F. Tipton. "The interactions of monoamine oxidase with some derivatives of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)." In Neurotransmitter Actions and Interactions. Springer Vienna, 1990. http://dx.doi.org/10.1007/978-3-7091-9050-0_26.

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"Product Subclass 19: 1,2,3,4-Tetrahydropyridines and Derivatives." In Houben–Weyl Methods of Molecular Transformations, edited by Molander, Trost, Abramite, et al. Georg Thieme Verlag, 2007. http://dx.doi.org/10.1055/sos-sd-033-00680.

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Taber, Douglass F. "Stereocontrolled C-N Ring Construction: The Pyne Synthesis of Hyacinthacine B 3." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0054.

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Keiji Maruoka of Kyoto University found (Organic Lett. 2010, 12, 1668) that the diazo amide 1 derived from the Oppolzer sultam condensed with the imine 2 to give the aziridine 3 with high stereocontrol. Andrei K. Yudin of the University of Toronto observed (Angew. Chem. Int. Ed. 2010, 49, 1607) that the unprotected aziridine aldehyde 4, which exists as a mixture of dimers, condensed smoothly with the Ohira reagent 5 to give the alkynyl aziridine 6. David M. Hodgson of the University of Oxford successfully (Angew. Chem. Int. Ed. 2010, 49, 2900) deprotonated the azetidine thioamide 7 to give, af
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Conference papers on the topic "Tetrahydropyridine derivatives"

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Callery, Patrick S., Wisut Wichitnithad, Elizabeth Borysiewicz, Gregory W. Konat, and Gregory W. Konat. "Abstract 3255: Tetrahydropyridine derivatives: Novel and potent histone demethylase LSD1 inhibitors." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3255.

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Journal articles
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