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Dissertations / Theses on the topic 'Tetramino'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Patience, J. M. "Routes to substituted tetramic acids." Thesis, University of Nottingham, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235998.

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2

Schollin, Mårten. "Formulation and Assessment of Hexamethylene-tetramine Filled Solid Fuel Grains." Thesis, KTH, Fiber- och polymerteknologi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-297507.

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Hybridraketer har inte sett så mycket användning som dess motsvarigheter som använder flytande eller fasta drivmedel. De främsta orsakerna kan förklaras med att hybridraketer historiskt sett haft lägre regressionshastighet och bränsletäthet. Inverkan av nackdelarna har dock minskat tack vare fortsatt forskning rörande hybridraketer. Tillsammans med de säkerhetsoch ekonomiska fördelar som kommer med hybridraketer har gjort hybridraketer ett mer konkurrenskraftiga. Hexaminbaserade fasta bränslen har formulerats och utvärderats med betoning att förbättra härdningstid och mekaniska egenskaper. Gen

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3

Bates, Andrew D. "New reactions in tetramic acid synthesis." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252629.

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4

Pillainayagam, Terence Anthony. "New methods in tetramic acid synthesis." Thesis, Loughborough University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416685.

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5

Law, Ching-Man (Carole). "Novel tetramic acids via 1,3-dipolar cycloaddition." Thesis, Loughborough University, 2008. https://dspace.lboro.ac.uk/2134/34454.

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This Ph.D. thesis has been concerned with the reinvestigation and improvement of the intermolecular 1,3-dipolar cycloaddition strategy using isoxazoles, towards the 3-acyltetramic acids (3-acylpyrrrolidine-2,4-diones) and also the investigation and development of the corresponding intramolecular strategy. A second generation of the intermolecular route was developed previously within our group and we have synthesised a variety of pyrroloisoxazoles, the 'masked' tetramic acids. We have modified and improved both the isoxazole formations and the peptide coupling reactions; we have further develo

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6

林躍年 and Yeuk-nin Lam. "Kinetic and mechanistic studies of some cis-macrocyclic tetramine and tetrathioether complexes of ruthenium." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1985. http://hub.hku.hk/bib/B31206979.

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7

Lam, Yeuk-nin. "Kinetic and mechanistic studies of some cis-macrocyclic tetramine and tetrathioether complexes of ruthenium /." [Hong Kong : University of Hong Kong], 1985. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12264015.

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8

Lewis, Ian. "Studies in the synthesis of polyene tetramic acid antibiotics." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/12412.

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9

Wilson, Jason B. "Synthesis and evaluation of tetramic acids as antimicrobial agents." View the abstract Download the full-text PDF version, 2008. http://etd.utmem.edu/ABSTRACTS/2008-055-Wilson-Index.htm.

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Thesis (M.S.)--University of Tennessee Health Science Center, 2008.<br>Title from title page screen (viewed on February 27, 2009). Research advisor: Richard E. Lee, Ph.D. Document formatted into pages (viii, 40 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 36-40).

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10

Duller, Kathryn April Marion. "A cycloaddition route to heterocyclic tricarbonyl natural products." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307821.

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11

Zhang, Jin. "Regulation of apolipoprotein A-I gene expression in Hep G2 cells depleted of copper by cupruretic tetramine." Diss., The University of Arizona, 1994. http://hdl.handle.net/10150/186914.

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Two cupruretic chelators, 2,3,2-tetramine and diamsar were used to deplete copper from Hep G2 cells. Studies using incremental concentrations of chelators, an average maximal depletion of 45% of cellular Cu amounting to 2.4 or 2.3 pmol Cu/μg DNA were attained after 24 h of incubation with 10 μM of tetramine or diamsar in basal medium containing 0.63 μM of Cu. In time-course studies, maximal depletion of Cu was rapidly reached after only 5 h of treatment with 50 μM of these chelators for cells cultured in basal medium. In long-term Cu depletion studies, cellular Cu was reduced more than 40% as

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12

Moore, M. Caragh. "Biosynthetic studies on tenellin and aminoisobutyrate metabolism in Streptomyces sp." Thesis, Durham University, 1998. http://etheses.dur.ac.uk/4837/.

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This thesis is divided into two parts. Part 1 covers the biosynthesis of the fungal metabolite tenellin, and Part 2 the metabolism of β-aminoisobutyrate m Streptomyces sp. Tenellin is a yellow pigment of the fungus Beamaria bassiana. It is of mixed biosynthetic origin, being derived from a polyketide moiety and the amino acid L-phenylalanine. The timing of the C-methylations of the polyketide chain is discussed in Chapter 2, which describes attempts to incorporate deuterium labelled partially assembled putative intermediates into the polyketide. The biosynthesis of the pyridone ring of tenelli

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13

Loscher, Sebastian [Verfasser], and Rainer [Akademischer Betreuer] Schobert. "Total synthesis of naturally occurring glycosylated tetramic acids / Sebastian Loscher. Betreuer: Rainer Schobert." Bayreuth : Universität Bayreuth, 2015. http://d-nb.info/1075249473/34.

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14

Hing, Sherry Ann Ong 1957. "COPPER DEFICIENCY AND HYPERLIPOPROTEINEMIA INDUCED BY N,N'-BIS-(2-AMINOETHYL)-1,3-PROPANE DIAMINE (2,3,2-TETRAMINE) IN RABBITS (CHELATORS)." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/276804.

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15

Melanophy, Claire. "Keteneylidenetriphenylphosphorane as a C2O building block in the synthesis of highly functionalised tetramic and tetronic acids." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972529942.

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16

Fischer, Joshua. "HIV-1 Integrase Inhibitors: A Formal Total Synthesis of Lithospermic Acid And Synthetic Studies Towards Integramycin." Thesis, The University of Sydney, 2007. http://hdl.handle.net/2123/2397.

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This thesis describes synthetic studies towards the HIV-1 integrase inhibitory natural products lithospermic acid and integramycin, resulting in a formal total synthesis of the former. A modular, flexible and convergent synthetic strategy to lithospermic acid was devised. In this approach, a Sonogashira coupling was used to unite the C1–C7 and C20–C27 fragments that were subsequently manipulated to then participate in the key step of the synthesis, a palladium-mediated carbonylative annulation. Reduction of the benzofuran nucleus with magnesium in methanol then provided the desired dihyd

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17

Fischer, Joshua. "HIV-1 Integrase Inhibitors: A Formal Total Synthesis of Lithospermic Acid And Synthetic Studies Towards Integramycin." University of Sydney, 2007. http://hdl.handle.net/2123/2397.

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Doctor of Philosophy (PhD)<br>This thesis describes synthetic studies towards the HIV-1 integrase inhibitory natural products lithospermic acid and integramycin, resulting in a formal total synthesis of the former. A modular, flexible and convergent synthetic strategy to lithospermic acid was devised. In this approach, a Sonogashira coupling was used to unite the C1–C7 and C20–C27 fragments that were subsequently manipulated to then participate in the key step of the synthesis, a palladium-mediated carbonylative annulation. Reduction of the benzofuran nucleus with magnesium in methanol then pr

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18

Sagiraju, Sarada. "Synthesis and Spectroscopic Study of Anticancer agent A-007 Prodrugs and Progress Towards the Synthesis of Tetramic acid Antibiotics." ScholarWorks@UNO, 2008. http://scholarworks.uno.edu/td/900.

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4, 4'-Dihydroxybenzophenone-2, 4-dinitrophenylhydrazone (A-007) has recently completed a phase-I clinical trial, and objective responses were seen in advanced breast cancer, lung cancer, ovarian cancer, melanoma, skin cancer and non-Hodgkin's lymphoma. Despite the promising results in the clinical trials, the major disadvantage to using A-007 as a broad-scale therapeutic is its poor water solubility. To make use of this promising anticancer drug either orally or intravenously, the short-term obstacle must be to overcome the limited solubility of A-007 in water. There are several approaches to

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19

Pingali, Subramanya. "Towards the Synthesis of Magnesidin." ScholarWorks@UNO, 2011. http://scholarworks.uno.edu/td/447.

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Magnesidin is a magnesium chelate of the 3-hexanoyl and 3-octanoyl tetramic acid derivatives isolated from Psuedomonas magensiorubra. Its activity against grampositive bacteria was found to be a specific target for Gingivitis, a dental plaque.Although the synthesis of magnesidin has been reported earlier, it was not reproducible. The highly polar nature and it’s ability to exhibit tautomerization makes their chemical behavior complex and difficult to predict its structure. A variety of reactions and an in depth understanding of the chemical structure is necessary to attain the synthesis of the

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20

Panduwawala, Tharindi. "Natural product guided antibacterial drug discovery : tetramates as core scaffolds." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:b507ca4d-ef35-4928-90a2-0a3f774a4ed2.

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This thesis describes the synthesis and biological evaluation of a library of compounds containing the tetramic acid core in search of novel antibacterial drug candidates. Chapter 1 discusses the need for new antibiotics due to the emergence of virulent bacterial strains resistant to clinically available drugs and the hiatus in the discovery of new replacement antibitoics that has become a global threat to human health. Different platforms for antibacterial drug discovery and the re-emergence of natural products-based approach that has gained importance in the quest for novel antibiotics are d

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21

Healy, Alan R. "Development of novel modulators of protein-protein interactions associated with cancer." Thesis, University of St Andrews, 2014. http://hdl.handle.net/10023/6316.

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An understanding of the underlying mechanisms by which proteins engage and communicate within the complex cellular environment is critical to the elucidation of the molecular basis of disease states and the development of safer, more efficacious drug therapies. Diverse cellular functions, including replication, transcription, cell growth and intracellular signal transduction, are governed by extensive networks of protein-protein interactions (PPIs). Disruption of the finely-tuned cellular networks due to the formation of aberrant or unregulated PPIs is implicated in the development and progres

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22

Pöhlmann, Milena. "Thermisch härtende Polymerverbundmaterialien als Basis für neue Befestigungssysteme." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2006. http://nbn-resolving.de/urn:nbn:de:swb:14-1165492370619-99312.

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Mit der Entwicklung und Einführung ökologischer Bauweise im Neubau sowie neuen Baustoffsystemen in Sandwichbauweise wird es zunehmend erforderlich, neue effektive Befestigungsvarianten zu entwickeln, die eine dauerhafte Fixierung auch unter sicherheitstechnischen Bestimmungen sowie aus Garantie- bzw. haftungsrechtlichen Gründen ermöglichen. Die aus der Praxis bisher bekannten chemischen Befestigungssysteme (Zweikomponentenverbundmörtel, Verbundankerpatronen) weisen hinsichtlich der Applikation unter bautechnischen Bedingungen noch einige Nachteile auf. Dazu gehören vor allem längere Aushärtung

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23

Amann, Jean-Marc. "Etude de procédés de captage du CO2 dans les centrales thermiques." Phd thesis, École Nationale Supérieure des Mines de Paris, 2007. http://pastel.archives-ouvertes.fr/pastel-00003445.

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La présente étude a pour objectif d'évaluer et de comparer entre eux divers procédés de captage du CO2 appliqués aux centrales thermiques alimentées en gaz naturel (NGCC) et au charbon pulvérisé (CP). Ces procédés consistent en un captage du CO2 des fumées en post-combustion par des solvants chimiques, une décarbonisation du gaz naturel avec captage du CO2 en pré-combustion par un solvant physique et l'oxy-combustion du combustible avec séparation frigorifique du CO2. Ces procédés ont été évalués à l'aide du logiciel de procédés Aspen PlusTM pour aider à choisir la meilleure option pour chaque

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24

余建和, Jian-He Yu, and 余建和. "Characteristics of a New Photosensitizer (tetramino-zinc-phthalocyanine) and Its Cancer Cell Damage Effects." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/j2q59n.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>105<br>A new type of Pc-series photosensitizer, tetramino-zinc-phthalocyanine (ZnPcN), which can link with alpha-Thio-omega-carboxy poly(ethylene glycol) (HS-PEG-COOH) through covalent bonding, such that its linkage with an Au nanoparticle (NP) becomes stronger for reducing the escape rate is synthesized. After demonstrating its fundamental photosensitizer characteristics, its escape behavior is compared with that of the commonly used PcS-series photosensitizer, tetrasulfonate-aluminum-phthalocyanine (AlPcS), through the measurements of the decreasing trends of abso

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25

Su, Jia-Yi, and 蘇家誼. "A New Approach to Chiral Tetramic Acid Derivatives." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/k5w7dq.

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26

Katzka, Catherine P. [Verfasser]. "Synthesis of tetramic acids and investigation of their biological properties / von Catherine P. Katzka." 2006. http://d-nb.info/997869550/34.

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27

Schab-Balcerzak, Ewa. "Badania nad nowymi semidrabinkowymi polimerami." Rozprawa doktorska, 1998. https://repolis.bg.polsl.pl/dlibra/docmetadata?showContent=true&id=3080.

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28

Schab-Balcerzak, Ewa. "Badania nad nowymi semidrabinkowymi polimerami." Rozprawa doktorska, 1998. https://delibra.bg.polsl.pl/dlibra/docmetadata?showContent=true&id=3080.

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29

Melanophy, Claire [Verfasser]. "Keteneylidenetriphenylphosphorane as a C2O building block in the synthesis of highly functionalised tetramic and tetronic acids / vorgelegt von Claire Melanophy." 2004. http://d-nb.info/972529942/34.

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