Log in

Relevant bibliographies by topics / Thalamic neuron / Journal articles

To see the other types of publications on this topic, follow the link: Thalamic neuron.

Journal articles on the topic 'Thalamic neuron'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Thalamic neuron.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Alloway, K. D., M. B. Wallace, and M. J. Johnson. "Cross-correlation analysis of cuneothalamic interactions in the rat somatosensory system: influence of receptive field topography and comparisons with thalamocortical interactions." Journal of Neurophysiology 72, no. 4 (1994): 1949–72. http://dx.doi.org/10.1152/jn.1994.72.4.1949.

Full text

Abstract:

1. We simultaneously recorded neuronal responses to cutaneous stimulation from matched somatotopic representations in the nucleus cuneatus and ventrobasal complex of intact, halothane-anesthetized rats. A total of 95 cuneate and 86 thalamic neurons representing hairy skin on the forelimb were activated by hair movements produced by air jets at multiple skin sites. Mean responsiveness was higher among neurons in nucleus cuneatus (34.4 spikes per stimulus) than in thalamus (23.7 spikes per stimulus), a result that was consistent with the greater proportion of “sustained” responses recorded in nu

APA, Harvard, Vancouver, ISO, and other styles

2

Pesavento, Michael J., Cynthia D. Rittenhouse, and David J. Pinto. "Response Sensitivity of Barrel Neuron Subpopulations to Simulated Thalamic Input." Journal of Neurophysiology 103, no. 6 (2010): 3001–16. http://dx.doi.org/10.1152/jn.01053.2009.

Full text

Abstract:

Our goal is to examine the relationship between neuron- and network-level processing in the context of a well-studied cortical function, the processing of thalamic input by whisker-barrel circuits in rodent neocortex. Here we focus on neuron-level processing and investigate the responses of excitatory and inhibitory barrel neurons to simulated thalamic inputs applied using the dynamic clamp method in brain slices. Simulated inputs are modeled after real thalamic inputs recorded in vivo in response to brief whisker deflections. Our results suggest that inhibitory neurons require more input to r

APA, Harvard, Vancouver, ISO, and other styles

3

Lytton, William W., Diego Contreras, Alain Destexhe, and Mircea Steriade. "Dynamic Interactions Determine Partial Thalamic Quiescence in a Computer Network Model of Spike-and-Wave Seizures." Journal of Neurophysiology 77, no. 4 (1997): 1679–96. http://dx.doi.org/10.1152/jn.1997.77.4.1679.

Full text

Abstract:

Lytton, William W., Diego Contreras, Alain Destexhe, and Mircea Steriade. Dynamic interactions determine partial thalamic quiescence in a computer network model of spike-and-wave seizures. J. Neurophysiol. 77: 1679–1696, 1997. In vivo intracellular recording from cat thalamus and cortex was performed during spontaneous spike-wave seizures characterized by synchronously firing cortical neurons correlated with the electroencephalogram. During these seizures, thalamic reticular (RE) neurons discharged with long spike bursts riding on a depolarization, whereas thalamocortical (TC) neurons were eit

APA, Harvard, Vancouver, ISO, and other styles

4

Kasten, Michael R., and Matthew P. Anderson. "Self-regulation of adult thalamocortical neurons." Journal of Neurophysiology 114, no. 1 (2015): 323–31. http://dx.doi.org/10.1152/jn.00800.2014.

Full text

Abstract:

The thalamus acts as a conduit for sensory and other information traveling to the cortex. In response to continuous sensory stimulation in vivo, the firing rate of thalamocortical neurons initially increases, but then within a minute firing rate decreases and T-type Ca2+ channel-dependent action potential burst firing emerges. While neuromodulatory systems could play a role in this inhibitory response, we instead report a novel and cell-autonomous inhibitory mechanism intrinsic to the thalamic relay neuron. Direct intracellular stimulation of thalamocortical neuron firing initially triggered a

APA, Harvard, Vancouver, ISO, and other styles

5

Khatri, Vivek, Randy M. Bruno, and Daniel J. Simons. "Stimulus-Specific and Stimulus-Nonspecific Firing Synchrony and Its Modulation by Sensory Adaptation in the Whisker-to-Barrel Pathway." Journal of Neurophysiology 101, no. 5 (2009): 2328–38. http://dx.doi.org/10.1152/jn.91151.2008.

Full text

Abstract:

The stimulus-evoked response of a cortical neuron depends on both details of the afferent signal and the momentary state of the larger network in which it is embedded. Consequently, identical sensory stimuli evoke highly variable responses. Using simultaneous recordings of thalamic barreloid and/or cortical barrel neurons in the rat whisker-to-barrel pathway, we determined the extent to which the responses of pairs of cells covary on a trial-by-trial basis. In the thalamus and cortical layer IV, a substantial component of trial-to-trial variability is independent of the specific parameters of

APA, Harvard, Vancouver, ISO, and other styles

6

Kumbhare, Deepak, Md Ali Azam, Ravi Hadimani, et al. "Healthy and pathological pallidal regulation of thalamic burst versus tonic mode firing: a computational simulation." NeuroReport 34, no. 16 (2023): 773–80. http://dx.doi.org/10.1097/wnr.0000000000001955.

Full text

Abstract:

The mechanisms by which the basal ganglia influence the pallidal-receiving thalamus remain to be adequately defined. Our prior in vivo recordings in fully alert normal and dystonic rats revealed that normally fast tonic discharging entopeduncular [EP, rodent equivalent of the globus pallidus internus (GPi)] neurons are pathologically slow, highly irregular, and bursty under dystonic conditions. This, in turn, induces pallidal-receiving thalamic movement-related neurons to change from a healthy burst predominant to a pathological tonic-predominant resting firing mode. This study aims to underst

APA, Harvard, Vancouver, ISO, and other styles

7

Azimirad, Vahid, and Mohammad Fattahi Sani. "Experimental Study of Reinforcement Learning in Mobile Robots Through Spiking Architecture of Thalamo-Cortico-Thalamic Circuitry of Mammalian Brain." Robotica 38, no. 9 (2019): 1558–75. http://dx.doi.org/10.1017/s0263574719001632.

Full text

Abstract:

SUMMARYIn this paper, the behavioral learning of robots through spiking neural networks is studied in which the architecture of the network is based on the thalamo-cortico-thalamic circuitry of the mammalian brain. According to a variety of neurons, the Izhikevich model of single neuron is used for the representation of neuronal behaviors. One thousand and ninety spiking neurons are considered in the network. The spiking model of the proposed architecture is derived and prepared for the learning problem of robots. The reinforcement learning algorithm is based on spike-timing-dependent plastici

APA, Harvard, Vancouver, ISO, and other styles

8

Viaene, Angela N., Iraklis Petrof, and S. Murray Sherman. "Synaptic Properties of Thalamic Input to Layers 2/3 and 4 of Primary Somatosensory and Auditory Cortices." Journal of Neurophysiology 105, no. 1 (2011): 279–92. http://dx.doi.org/10.1152/jn.00747.2010.

Full text

Abstract:

We studied the synaptic profile of thalamic inputs to cells in layers 2/3 and 4 of primary somatosensory (S1) and auditory (A1) cortices using thalamocortical slices from mice age postnatal days 10–18. Stimulation of the ventral posterior medial nucleus (VPM) or ventral division of the medial geniculate body (MGBv) resulted in two distinct classes of responses. The response of all layer 4 cells and a minority of layers 2/3 cells to thalamic stimulation was Class 1, including paired-pulse depression, all-or-none responses, and the absence of a metabotropic component. On the other hand, the majo

APA, Harvard, Vancouver, ISO, and other styles

9

Thomas, Elizabeth, and Thierry Grisar. "Increased Synchrony with Increase of a Low-Threshold Calcium Conductance in a Model Thalamic Network: A Phase-Shift Mechanism." Neural Computation 12, no. 7 (2000): 1553–71. http://dx.doi.org/10.1162/089976600300015268.

Full text

Abstract:

A computer model of a thalamic network was used in order to examine the effects of an isolated augmentation in a low-threshold calcium current. Such an isolated augmentation has been observed in the reticular thalamic (RE) nucleus of the genetic absence epilepsy rat from the Strasbourg (GAERS) model of absence epilepsy. An augmentation of the low-threshold calcium conductance in the RE neurons (gTs) of the model thalamic network was found to lead to an increase in the synchronized firing of the network. This supports the hypothesis that the isolated increase in gTs may be responsible for epile

APA, Harvard, Vancouver, ISO, and other styles

10

Johnson, M. J., and K. D. Alloway. "Cross-correlation analysis reveals laminar differences in thalamocortical interactions in the somatosensory system." Journal of Neurophysiology 75, no. 4 (1996): 1444–57. http://dx.doi.org/10.1152/jn.1996.75.4.1444.

Full text

Abstract:

1. Spontaneous and stimulus-induced activity were recorded from corresponding somatotopic representations in the ventroposterolateral nucleus (VPL) of the thalamus and primary somatosensory (SI) cortex of intact, halothane-anesthetized cats. Thalamic and cortical neurons with overlapping receptive fields on the hairy skin of the forelimb were excited by a series of interleaved air jets aimed at multiple skin sites. 2. The laminar locations of 68% (240 of 355) of the neurons recorded in SI cortex were histologically reconstructed and responses of these 240 SI neurons were analyzed with respect

APA, Harvard, Vancouver, ISO, and other styles

11

Goldberg, Jesse H., Michael A. Farries, and Michale S. Fee. "Integration of cortical and pallidal inputs in the basal ganglia-recipient thalamus of singing birds." Journal of Neurophysiology 108, no. 5 (2012): 1403–29. http://dx.doi.org/10.1152/jn.00056.2012.

Full text

Abstract:

The basal ganglia-recipient thalamus receives inhibitory inputs from the pallidum and excitatory inputs from cortex, but it is unclear how these inputs interact during behavior. We recorded simultaneously from thalamic neurons and their putative synaptically connected pallidal inputs in singing zebra finches. We find, first, that each pallidal spike produces an extremely brief (∼5 ms) pulse of inhibition that completely suppresses thalamic spiking. As a result, thalamic spikes are entrained to pallidal spikes with submillisecond precision. Second, we find that the number of thalamic spikes tha

APA, Harvard, Vancouver, ISO, and other styles

12

Zhang, Yusheng, Shihui Xing, Jian Zhang та ін. "Reduction of β-Amyloid Deposits by γ-Secretase Inhibitor is Associated with the Attenuation of Secondary Damage in the Ipsilateral Thalamus and Sensory Functional Improvement after Focal Cortical Infarction in Hypertensive Rats". Journal of Cerebral Blood Flow & Metabolism 31, № 2 (2010): 572–79. http://dx.doi.org/10.1038/jcbfm.2010.127.

Full text

Abstract:

Abnormal β-amyloid (Aβ) deposits in the thalamus have been reported after cerebral cortical infarction. In this study, we investigated the association of Aβ deposits, with the secondary thalamic damage after focal cortical infarction in rats. Thirty-six stroke-prone renovascular hypertensive rats were subjected to distal middle cerebral artery occlusion (MCAO) and then randomly divided into MCAO, vehicle, and N-[ N-(3,5-difluorophenacetyl)-l-alanyl]- S-phenylglycine t-butyl ester (DAPT) groups and 12 sham-operated rats as control. The DAPT was administered orally at 72 hours after MCAO. Seven

APA, Harvard, Vancouver, ISO, and other styles

13

Shoykhet, Michael, and Daniel J. Simons. "Development of Thalamocortical Response Transformations in the Rat Whisker-Barrel System." Journal of Neurophysiology 99, no. 1 (2008): 356–66. http://dx.doi.org/10.1152/jn.01063.2007.

Full text

Abstract:

Extracellular single-unit recordings were used to characterize responses of thalamic barreloid and cortical barrel neurons to controlled whisker deflections in 2, 3-, and 4-wk-old and adult rats in vivo under fentanyl analgesia. Results indicate that response properties of thalamic and cortical neurons diverge during development. Responses to deflection onsets and offsets among thalamic neurons mature in parallel, whereas among cortical neurons responses to deflection offsets become disproportionately smaller with age. Thalamic neuron receptive fields become more multiwhisker, whereas those of

APA, Harvard, Vancouver, ISO, and other styles

14

Gursky, Zachary H., and Anna Y. Klintsova. "Changes in Representation of Thalamic Projection Neurons within Prefrontal-Thalamic-Hippocampal Circuitry in a Rat Model of Third Trimester Binge Drinking." Brain Sciences 11, no. 3 (2021): 323. http://dx.doi.org/10.3390/brainsci11030323.

Full text

Abstract:

Alcohol exposure (AE) during the third trimester of pregnancy—a period known as the brain growth spurt (BGS)—could result in a diagnosis of a fetal alcohol spectrum disorder (FASD), a hallmark of which is impaired executive functioning (EF). Coordinated activity between prefrontal cortex and hippocampus is necessary for EF and thalamic nucleus reuniens (Re), which is required for prefrontal-hippocampal coordination, is damaged following high-dose AE during the BGS. The current experiment utilized high-dose AE (5.25 g/kg/day) during the BGS (i.e., postnatal days 4–9) of Long-Evans rat pups. AE

APA, Harvard, Vancouver, ISO, and other styles

15

Pesavento, Michael J., and David J. Pinto. "Network and neuronal membrane properties in hybrid networks reciprocally regulate selectivity to rapid thalamocortical inputs." Journal of Neurophysiology 108, no. 9 (2012): 2452–72. http://dx.doi.org/10.1152/jn.00914.2011.

Full text

Abstract:

Rapidly changing environments require rapid processing from sensory inputs. Varying deflection velocities of a rodent's primary facial vibrissa cause varying temporal neuronal activity profiles within the ventral posteromedial thalamic nucleus. Local neuron populations in a single somatosensory layer 4 barrel transform sparsely coded input into a spike count based on the input's temporal profile. We investigate this transformation by creating a barrel-like hybrid network with whole cell recordings of in vitro neurons from a cortical slice preparation, embedding the biological neuron in the sim

APA, Harvard, Vancouver, ISO, and other styles

16

Crunelli, Vincenzo, Kate L. Blethyn, David W. Cope, et al. "Novel neuronal and astrocytic mechanisms in thalamocortical loop dynamics." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 357, no. 1428 (2002): 1675–93. http://dx.doi.org/10.1098/rstb.2002.1155.

Full text

Abstract:

In this review, we summarize three sets of findings that have recently been observed in thalamic astrocytes and neurons, and discuss their significance for thalamocortical loop dynamics. (i) A physiologically relevant ‘window’ component of the low–voltage–activated, T–type Ca 2+ current ( I Twindow ) plays an essential part in the slow (less than 1 Hz) sleep oscillation in adult thalamocortical (TC) neurons, indicating that the expression of this fundamental sleep rhythm in these neurons is not a simple reflection of cortical network activity. It is also likely that I Twindow underlies one of

APA, Harvard, Vancouver, ISO, and other styles

17

Kwegyir-Afful, E. E., H. T. Kyriazi, and D. J. Simons. "Weaker feedforward inhibition accounts for less pronounced thalamocortical response transformation in mouse vs. rat barrels." Journal of Neurophysiology 110, no. 10 (2013): 2378–92. http://dx.doi.org/10.1152/jn.00574.2012.

Full text

Abstract:

Feedforward inhibition is a common motif of thalamocortical circuits. Strong engagement of inhibitory neurons by thalamic inputs enhances response differentials between preferred and nonpreferred stimuli. In rat whisker-barrel cortex, robustly driven inhibitory barrel neurons establish a brief epoch during which synchronous or near-synchronous thalamic firing produces larger responses to preferred stimuli, such as high-velocity deflections of the principal whisker in a preferred direction. Present experiments in mice show that barrel neuron responses to preferred vs. nonpreferred stimuli diffe

APA, Harvard, Vancouver, ISO, and other styles

18

Lenz, F. A., C. J. Jaeger, M. S. Seike, Y. C. Lin, and S. G. Reich. "Single-Neuron Analysis of Human Thalamus in Patients With Intention Tremor and Other Clinical Signs of Cerebellar Disease." Journal of Neurophysiology 87, no. 4 (2002): 2084–94. http://dx.doi.org/10.1152/jn.00049.2001.

Full text

Abstract:

Tremor that occurs as a result of a cerebellar lesion, cerebellar tremor, is characteristically an intention tremor. Thalamic activity may be related to cerebellar tremor because transmission of some cerebellar efferent signals occurs via the thalamus and cortex to the periphery. We have now studied thalamic neuronal activity in a cerebellar relay nucleus (ventral intermediate—Vim) and a pallidal relay nucleus (ventralis oral posterior—Vop) during thalamotomy in patients with intention tremor and other clinical signs of cerebellar disease (tremor patients). The activity of single neurons and t

APA, Harvard, Vancouver, ISO, and other styles

19

Verhagen, Justus V., Barbara K. Giza, and Thomas R. Scott. "Effect of Amiloride on Gustatory Responses in the Ventroposteromedial Nucleus of the Thalamus in Rats." Journal of Neurophysiology 93, no. 1 (2005): 157–66. http://dx.doi.org/10.1152/jn.00823.2003.

Full text

Abstract:

The existence of gustatory neuron types has been demonstrated in the chorda tympani nerve and the nucleus of the solitary tract (NTS) of rats and hamsters through the oral application of amiloride, a sodium channel blocker. At these lower-order levels, amiloride was shown to reduce the response to sodium and lithium salts in sodium- and sugar-oriented cells, while leaving those of acid- and quinine-oriented neurons unmodified. We extended this investigation to higher-order levels by determining whether amiloride suppressed the responses of cells at the 4th-order gustatory relay in the thalamus

APA, Harvard, Vancouver, ISO, and other styles

20

Yoshioka, Takashi, Jonathan B. Levitt, and Jennifer S. Lund. "Independence and merger of thalamocortical channels within macaque monkey primary visual cortex: Anatomy of interlaminar projections." Visual Neuroscience 11, no. 3 (1994): 467–89. http://dx.doi.org/10.1017/s0952523800002406.

Full text

Abstract:

AbstractAn important issue in understanding the function of primary visual cortex in the macaque monkey is how the several efferent neuron groups projecting to extrastriate cortex acquire their different response properties. To assist our understanding of this issue, we have compared the anatomical distribution of VI intrinsic relays that carry information derived from magno- (M) and parvocellular (P) divisions of the dorsal lateral geniculate nucleus between thalamic recipient neurons and interareal efferent neuron groups within area VI. We used small, iontophoretic injections of biocytin pla

APA, Harvard, Vancouver, ISO, and other styles

21

Pinto, David J., Joshua C. Brumberg, and Daniel J. Simons. "Circuit Dynamics and Coding Strategies in Rodent Somatosensory Cortex." Journal of Neurophysiology 83, no. 3 (2000): 1158–66. http://dx.doi.org/10.1152/jn.2000.83.3.1158.

Full text

Abstract:

Previous experimental studies of both cortical barrel and thalamic barreloid neuron responses in rodent somatosensory cortex have indicated an active role for barrel circuitry in processing thalamic signals. Previous modeling studies of the same system have suggested that a major function of the barrel circuit is to render the response magnitude of barrel neurons particularly sensitive to the temporal distribution of thalamic input. Specifically, thalamic inputs that are initially synchronous strongly engage recurrent excitatory connections in the barrel and generate a response that briefly wi

APA, Harvard, Vancouver, ISO, and other styles

22

Deymeer, F., T. W. Smith, U. DeGirolami, and D. A. Drachman. "Thalamic dementia and motor neuron disease." Neurology 39, no. 1 (1989): 58. http://dx.doi.org/10.1212/wnl.39.1.58.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Lu, Meili, Yingmei Qin, Huiyan Li, Yanqiu Che, Chunxiao Han, and Xile Wei. "Calcium conductance-dependent network synchronization is differentially modulated by firing frequency." International Journal of Modern Physics B 33, no. 15 (2019): 1950160. http://dx.doi.org/10.1142/s0217979219501601.

Full text

Abstract:

Synchronous oscillations in certain frequencies of the sub-thalamic nucleus (STN) neurons are closely related to the physical symptoms of Parkinson’s disease (PD). Recent results have highlighted the importance of calcium channels in the synchronization properties and regulation of STN neurons. In this paper, a novel hybrid neuron model which can capture the electrophysiological signature of neurons with low or high density of calcium channels is used to explore the synchronization propensity and regulation by firing frequencies of neurons. Numerical simulations show that the synchronization p

APA, Harvard, Vancouver, ISO, and other styles

24

Shu, Yousheng, and David A. McCormick. "Inhibitory Interactions Between Ferret Thalamic Reticular Neurons." Journal of Neurophysiology 87, no. 5 (2002): 2571–76. http://dx.doi.org/10.1152/jn.00850.2001.

Full text

Abstract:

The thalamic reticular nucleus (nRt) provides an important inhibitory input to thalamic relay nuclei and is central in the generation of both normal and abnormal thalamocortical activities. Although local inhibitory interactions between these neurons may play an important role in controlling thalamocortical activities, the physiological features of this interaction have not been fully investigated. Here we sought to establish the nature of inhibitory interaction between nRt neurons with intracellular and extracellular recordings in slices of ferret nRt maintained in vitro. In many nRt neurons,

APA, Harvard, Vancouver, ISO, and other styles

25

Alloway, K. D., M. J. Johnson, and M. B. Wallace. "Thalamocortical interactions in the somatosensory system: interpretations of latency and cross-correlation analyses." Journal of Neurophysiology 70, no. 3 (1993): 892–908. http://dx.doi.org/10.1152/jn.1993.70.3.892.

Full text

Abstract:

1. Isolated extracellular neuronal responses to cutaneous stimulation were simultaneously recorded from corresponding peripheral representations in the ventrobasal nucleus and primary somatosensory cortex of intact, halothane-anesthetized rats. Thalamic and cortical neurons representing hairy skin on the forelimb were activated by hair movements produced by a series of 50 or 100 discrete air jets. A corresponding set of neurons representing the glabrous pads of the hind paw were activated by a similar number of punctate mechanical displacements. 2. Cortical electrode penetrations were histolog

APA, Harvard, Vancouver, ISO, and other styles

26

Herrero-Navarro, Álvaro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al. "Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming." Science Advances 7, no. 15 (2021): eabe8978. http://dx.doi.org/10.1126/sciadv.abe8978.

Full text

Abstract:

Neural cell diversity is essential to endow distinct brain regions with specific functions. During development, progenitors within these regions are characterized by specific gene expression programs, contributing to the generation of diversity in postmitotic neurons and astrocytes. While the region-specific molecular diversity of neurons and astrocytes is increasingly understood, whether these cells share region-specific programs remains unknown. Here, we show that in the neocortex and thalamus, neurons and astrocytes express shared region-specific transcriptional and epigenetic signatures. T

APA, Harvard, Vancouver, ISO, and other styles

27

Drexler, Richard, Antonia Drinnenberg, Avishai Gavish, et al. "CNSC-28. BRAINSTEM NEUROMODULATORY NEURONS PROMOTE GLIOMA GROWTH LOCALLY AND VIA LONG-RANGE PROJECTIONS TO MIDLINE AND CORTICAL STRUCTURES." Neuro-Oncology 26, Supplement_8 (2024): viii47. http://dx.doi.org/10.1093/neuonc/noae165.0184.

Full text

Abstract:

Abstract Neuronal activity robustly drives glioma progression, mediated through paracrine and synaptic neuron-to-glioma interactions. Recent research has focused on glutamatergic and GABAergic neurons, while the impact of neuromodulatory neuron subpopulations and their long-range projections remain unexplored. Here, we explore the glioma-promoting effects of serotonergic and cholinergic brainstem neurons, which project to defined regions throughout the brain. By employing optogenetic stimulation of midbrain serotonergic or cholinergic neurons in mice bearing high-grade glioma allografts or xen

APA, Harvard, Vancouver, ISO, and other styles

28

Govindaiah, G., and Charles L. Cox. "Modulation of thalamic neuron excitability by orexins." Neuropharmacology 51, no. 3 (2006): 414–25. http://dx.doi.org/10.1016/j.neuropharm.2006.03.030.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Golomb, D., X. J. Wang, and J. Rinzel. "Synchronization properties of spindle oscillations in a thalamic reticular nucleus model." Journal of Neurophysiology 72, no. 3 (1994): 1109–26. http://dx.doi.org/10.1152/jn.1994.72.3.1109.

Full text

Abstract:

1. We address the hypothesis of Steriade and colleagues that the thalamic reticular nucleus (RE) is a pacemaker for thalamocortical spindle oscillations by developing and analyzing a model of a large population of all-to-all coupled inhibitory RE neurons. 2. Each RE neuron has three ionic currents: a low-threshold T-type Ca2+ current (ICa-T), a calcium-activated potassium current (IAHP) and a leakage current (IL). ICa-T underlies a cell's postinhibitory rebound properties, whereas IAHP hyperpolarizes the neuron after a burst. Each neuron, which is a conditional oscillator, is coupled to all ot

APA, Harvard, Vancouver, ISO, and other styles

30

Moreno, Sandra, Roberta Nardacci, and Maria Paola Cerù. "Regional and Ultrastructural Immunolocalization of Copper-Zinc Superoxide Dismutase in Rat Central Nervous System." Journal of Histochemistry & Cytochemistry 45, no. 12 (1997): 1611–22. http://dx.doi.org/10.1177/002215549704501204.

Full text

Abstract:

We examined the distribution of copper-zinc superoxide dismutase (CuZn-SOD) in adult rat central nervous system by light and electron microscopic immunocytochemistry, using an affinity-purified polyclonal antibody. The enzyme appeared to be exclusively localized in neurons. No immunoreactivity was seen in non-neuronal cells. The staining intensity was variable, depending on the brain region and, within the same region, on the neuron type. Highly immunoreactive elements included cortical neurons evenly distributed in the different layers, hippocampal interneurons, neurons of the reticular thala

APA, Harvard, Vancouver, ISO, and other styles

31

Lenz, F. A., C. J. Jaeger, M. S. Seike, et al. "Thalamic Single Neuron Activity in Patients With Dystonia: Dystonia-Related Activity and Somatic Sensory Reorganization." Journal of Neurophysiology 82, no. 5 (1999): 2372–92. http://dx.doi.org/10.1152/jn.1999.82.5.2372.

Full text

Abstract:

Indirect evidence suggests that the thalamus contributes to abnormal movements occurring in patients with dystonia (dystonia patients). The present study tested the hypothesis that thalamic activity contributes to the dystonic movements that occur in such patients. During these movements, spectral analysis of electromyographic (EMG) signals in flexor and extensor muscles of the wrist and elbow exhibited peak EMG power in the lowest frequency band [0–0.78 Hz (mean: 0.39 Hz) dystonia frequency] for 60–85% of epochs studied during a pointing task. Normal controls showed low-frequency peaks for &l

APA, Harvard, Vancouver, ISO, and other styles

32

Minère, Marielle, Hannah Wilhelms, Bojana Kuzmanovic, et al. "Thalamic opioids from POMC satiety neurons switch on sugar appetite." Science 387, no. 6735 (2025): 750–58. https://doi.org/10.1126/science.adp1510.

Full text

Abstract:

High sugar–containing foods are readily consumed, even after meals and beyond fullness sensation (e.g., as desserts). Although reward-driven processing of palatable foods can promote overeating, the neurobiological mechanisms that underlie the selective appetite for sugar in states of satiety remain unclear. Hypothalamic pro-opiomelanocortin (POMC) neurons are principal regulators of satiety because they decrease food intake through excitatory melanocortin neuropeptides. We discovered that POMC neurons not only promote satiety in fed conditions but concomitantly switch on sugar appetite, which

APA, Harvard, Vancouver, ISO, and other styles

33

Gribkova, Ekaterina D., Baher A. Ibrahim, and Daniel A. Llano. "A novel mutual information estimator to measure spike train correlations in a model thalamocortical network." Journal of Neurophysiology 120, no. 6 (2018): 2730–44. http://dx.doi.org/10.1152/jn.00012.2018.

Full text

Abstract:

The impact of thalamic state on information transmission to the cortex remains poorly understood. This limitation exists due to the rich dynamics displayed by thalamocortical networks and because of inadequate tools to characterize those dynamics. Here, we introduce a novel estimator of mutual information and use it to determine the impact of a computational model of thalamic state on information transmission. Using several criteria, this novel estimator, which uses an adaptive partition, is shown to be superior to other mutual information estimators with uniform partitions when used to analyz

APA, Harvard, Vancouver, ISO, and other styles

34

Tanibuchi, Ikuo, Hiroyuki Kitano, and Kohnosuke Jinnai. "Substantia Nigra Output to Prefrontal Cortex Via Thalamus in Monkeys. I. Electrophysiological Identification of Thalamic Relay Neurons." Journal of Neurophysiology 102, no. 5 (2009): 2933–45. http://dx.doi.org/10.1152/jn.91287.2008.

Full text

Abstract:

A few studies have been performed in primate basal ganglia–thalamo–prefrontal pathways. Nevertheless, their electrophysiological properties and anatomical arrangements remain obscure. This study examined them in nigro-thalamo-cortical pathways from the substantia nigra pars reticulata (SNr) to the frontal cortex (FRC) via the mediodorsal (MD) and ventral anterior (VA) thalamus in monkeys. First, single thalamocortical neurons with SNr input were identified by antidromic responses to FRC stimulation and by inhibitory orthodromic responses with short latencies (<5 ms) to SNr stimulation. Seco

APA, Harvard, Vancouver, ISO, and other styles

35

Zhu, Zhi-ru, Fenglian Xu, Wei-gang Ji, et al. "Synaptic mechanisms underlying thalamic activation-induced plasticity in the rat auditory cortex." Journal of Neurophysiology 111, no. 9 (2014): 1746–58. http://dx.doi.org/10.1152/jn.00180.2013.

Full text

Abstract:

Electrical stimulation of ventral division of medial geniculate body (MGBv) neurons evokes a shift of the frequency-tuning curves of auditory cortical (AC) neurons toward the best frequency (BF) of the stimulated MGBv neurons (frequency-specific plasticity). The shift of BF is induced by inhibition of responses at the BF of the recorded AC neuron, with coincident facilitation of responses at the BF of the stimulated MGBv neuron. However, the synaptic mechanisms are not yet understood. We hypothesize that activation of thalamocortical synaptic transmission and receptor function may contribute t

APA, Harvard, Vancouver, ISO, and other styles

36

Smith, Gregory D., Charles L. Cox, S. Murray Sherman, and John Rinzel. "Fourier Analysis of Sinusoidally Driven Thalamocortical Relay Neurons and a Minimal Integrate-and-Fire-or-Burst Model." Journal of Neurophysiology 83, no. 1 (2000): 588–610. http://dx.doi.org/10.1152/jn.2000.83.1.588.

Full text

Abstract:

We performed intracellular recordings of relay neurons from the lateral geniculate nucleus of a cat thalamic slice preparation. We measured responses during both tonic and burst firing modes to sinusoidal current injection and performed Fourier analysis on these responses. For comparison, we constructed a minimal “integrate-and-fire-or-burst” (IFB) neuron model that reproduces salient features of the relay cell responses. The IFB model is constrained to quantitatively fit our Fourier analysis of experimental relay neuron responses, including: the temporal tuning of the response in both tonic a

APA, Harvard, Vancouver, ISO, and other styles

37

Tancredi, Virginia, Giuseppe Biagini, Margherita D'Antuono, Jacques Louvel, René Pumain, and Massimo Avoli. "Spindle-Like Thalamocortical Synchronization in a Rat Brain Slice Preparation." Journal of Neurophysiology 84, no. 2 (2000): 1093–97. http://dx.doi.org/10.1152/jn.2000.84.2.1093.

Full text

Abstract:

We obtained rat brain slices (550–650 μm) that contained part of the frontoparietal cortex along with a portion of the thalamic ventrobasal complex (VB) and of the reticular nucleus (RTN). Maintained reciprocal thalamocortical connectivity was demonstrated by VB stimulation, which elicited orthodromic and antidromic responses in the cortex, along with re-entry of thalamocortical firing originating in VB neurons excited by cortical output activity. In addition, orthodromic responses were recorded in VB and RTN following stimuli delivered in the cortex. Spontaneous and stimulus-induced coherent

APA, Harvard, Vancouver, ISO, and other styles

38

Rush, Maureen E., and John Rinzel. "Analysis of bursting in a thalamic neuron model." Biological Cybernetics 71, no. 4 (1994): 281–91. http://dx.doi.org/10.1007/bf00239616.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Gupta, Shruti, and Jyotsna Singh. "Effect of applied current on sub-thalamic neuron." CSI Transactions on ICT 4, no. 2-4 (2016): 183–85. http://dx.doi.org/10.1007/s40012-016-0120-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Rush, Maureen E., and John Rinzel. "Analysis of bursting in a thalamic neuron model." Biological Cybernetics 71, no. 4 (1994): 281–91. http://dx.doi.org/10.1007/s004220050090.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Cox, C. L., J. R. Huguenard, and D. A. Prince. "Cholecystokinin depolarizes rat thalamic reticular neurons by suppressing a K+ conductance." Journal of Neurophysiology 74, no. 3 (1995): 990–1000. http://dx.doi.org/10.1152/jn.1995.74.3.990.

Full text

Abstract:

1. The thalamic reticular nucleus (nRt) is innervated by cholecystokinin (CCK)-containing neurons and contains CCK binding sites. We used tight-seal, whole cell recording techniques with in vitro rat thalamic slices to investigate the action of CCK on neurons in nRt and ventrobasal thalamus (VB). 2. Brief applications of the CCK agonist cholecystokinin octapeptide (26-33) sulfated (CCK8S) evoked prolonged spike discharges in nRt neurons but had no direct effects on VB neuron activity. This selective excitatory action of CCK8S in nRt resulted from a long-lasting membrane depolarization (2-10 mi

APA, Harvard, Vancouver, ISO, and other styles

42

Nielsen, Rune Damgaard, Maja Abitz, and Bente Pakkenberg. "NEURON AND GLIAL CELL NUMBERS IN THE MEDIODORSAL THALAMIC NUCLEUS IN BRAINS OF SCHIZOPHRENIC SUBJECTS." Image Analysis & Stereology 27, no. 3 (2011): 133. http://dx.doi.org/10.5566/ias.v27.p133-141.

Full text

Abstract:

Several stereological studies of schizophrenic subjects have shown reduction in both the total number of neurons and in the total volume of the mediodorsal thalamic nucleus (MD). This is in contrast to other studies in that no differences have been found. Using systematic random sampling and an optical fractionator design, the total number of neuron and glial cells in the MD subdivisions: parvocellular (MDPC), magnocellular (MDMC), and densocellular (MDDC) were counted in brains from 9 schizophrenic and 8 control subjects. The control subjects were age, height and body-weight matched to the sc

APA, Harvard, Vancouver, ISO, and other styles

43

Douglas, Rodney J., Kevan A. C. Martin, and David Whitteridge. "A Canonical Microcircuit for Neocortex." Neural Computation 1, no. 4 (1989): 480–88. http://dx.doi.org/10.1162/neco.1989.1.4.480.

Full text

Abstract:

We have used microanatomy derived from single neurons, and in vivo intracellular recordings to develop a simplified circuit of the visual cortex. The circuit explains the intracellular responses to pulse stimulation in terms of the interactions between three basic populations of neurons, and reveals the following features of cortical processing that are important to computational theories of neocortex. First, inhibition and excitation are not separable events. Activation of the cortex inevitably sets in motion a sequence of excitation and inhibition in every neuron. Second, the thalamic input

APA, Harvard, Vancouver, ISO, and other styles

44

Shosaku, A. "Cross-correlation analysis of a recurrent inhibitory circuit in the rat thalamus." Journal of Neurophysiology 55, no. 5 (1986): 1030–43. http://dx.doi.org/10.1152/jn.1986.55.5.1030.

Full text

Abstract:

Spontaneous activities of vibrissa-responding neurons in the rat ventrobasal complex (VB) and somatosensory part of the thalamic reticular nucleus (S-TR) were simultaneously recorded and subjected to cross-correlation analysis to investigate the functional organization of recurrent inhibitory action of the S-TR on VB neurons. Excitatory and/or inhibitory interactions were found between approximately 75% (25/34) of the pairs of S-TR and VB neurons with receptive fields (RFs) on the same vibrissa. In contrast, there was no significant interaction between 54 pairs of neurons having RFs on differe

APA, Harvard, Vancouver, ISO, and other styles

45

Swadlow, Harvey A., and Alexander G. Gusev. "The Influence of Single VB Thalamocortical Impulses on Barrel Columns of Rabbit Somatosensory Cortex." Journal of Neurophysiology 83, no. 5 (2000): 2802–13. http://dx.doi.org/10.1152/jn.2000.83.5.2802.

Full text

Abstract:

Extracellular recordings were obtained from single neurons in ventrobasal (VB) thalamus of awake rabbits while field potentials were recorded at various depths within topographically aligned and nonaligned barrel columns of somatosensory cortex (S1). Spike-triggered averages of cortical field potentials were obtained following action potentials in thalamic neurons. Action potentials in a VB neuron elicited a cortical response within layer 4 with three distinct components. 1) A biphasic, initially positive response (latency <1 ms) was interpreted to reflect activation of the VB axon terminal

APA, Harvard, Vancouver, ISO, and other styles

46

Zhou, Hui, Bo Lu, Huaguang Gu, Xianjun Wang, and Yifan Liu. "Complex nonlinear dynamics of bursting of thalamic neurons related to Parkinson's disease." Electronic Research Archive 32, no. 1 (2023): 109–33. http://dx.doi.org/10.3934/era.2024006.

Full text

Abstract:

<abstract><p>Parkinson's disease is associated with bursting of the thalamic (TC) neuron, which receives the inhibitory synaptic current of the basal ganglia composed of multiple nuclei; deep brain stimulation (DBS) applied to the basal ganglia can eliminate the bursting to recover to the normal state. In this paper, the complex nonlinear dynamics for the appearance and disappearance of the bursting are obtained in a widely used theoretical model of a neuronal network. First, through a bifurcation analysis, isolated TC neurons exhibit paradoxical bursting induced from the resting s

APA, Harvard, Vancouver, ISO, and other styles

47

Lytton, William W., and Terrence J. Sejnowski. "Computer model of ethosuximide's effect on a thalamic neuron." Annals of Neurology 32, no. 2 (1992): 131–39. http://dx.doi.org/10.1002/ana.410320204.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Devia, Christ, Manuel A. Duarte-Mermoud, and María de la Luz Aylwin O. "Knowledge-Based Expert Control of Thalamic Neuron Firing Mode." Asian Journal of Control 16, no. 1 (2012): 117–25. http://dx.doi.org/10.1002/asjc.599.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Morin, L. R., and J. H. Blanchard. "Neuropeptide Y and enkephalin immunoreactivity in retinorecipient nuclei of the hamster pretectum and thalamus." Visual Neuroscience 14, no. 4 (1997): 765–77. http://dx.doi.org/10.1017/s0952523800012712.

Full text

Abstract:

AbstractThis investigation was stimulated by the historical confusion concerning the identity of certain pretectal nuclei and by large differences reported between species with respect to which nuclei receive retinal innervation. Subcortical visual nuclei were studied using immunohistochemistry to identify retinal projections labeled following intraocular injection of cholera toxin, b fragment. In addition, neuropeptide Y (NPY) or enkephalin (ENK) immunoreactive cells and fibers were also evaluated in the retinorecipient pretectal and thalamic areas. The results confirm the established view th

APA, Harvard, Vancouver, ISO, and other styles

50

Tanibuchi, Ikuo, and Patricia S. Goldman-Rakic. "Dissociation of Spatial-, Object-, and Sound-Coding Neurons in the Mediodorsal Nucleus of the Primate Thalamus." Journal of Neurophysiology 89, no. 2 (2003): 1067–77. http://dx.doi.org/10.1152/jn.00207.2002.

Full text

Abstract:

The mediodorsal nucleus (MD) is the thalamic gateway to the prefrontal cortex, an area of the brain associated with spatial and object working memory functions. We have recorded single-neuron activities from the MD nucleus in monkeys trained to perform spatial tasks with peripheral visual stimuli and a nonspatial task with foveally presented pictures of objects and faces—tasks identical to those we have previously used to map regional specializations in the dorso- and ventro-lateral prefrontal cortex, respectively. We found that MD neurons exhibited categorical specificity—either responding se

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!