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Dissertations / Theses on the topic 'The chronic obstructive pulmonary disease (COPD)'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Baldrick, Francina Rose. "Diet and chronic obstructive pulmonary disease (COPD)." Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527657.

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2

McAllister, David Anthony. "Chronic obstructive pulmonary disease, pulmonary function and cardiovascular disease." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5615.

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Cardiovascular disease is common in Chronic Obstructive Pulmonary Disease (COPD), and forced expiratory volume in one second (FEV1) independently predicts cardiovascular morbidity and mortality. Pathological changes in the systemic vasculature have been proposed as potential mechanisms linking COPD to cardiovascular disease, and patients with COPD may be at increased risk of acute myocardial infarction during acute exacerbations. Notwithstanding causation, FEV1 may be a useful prognostic marker in patients undergoing cardiac surgery. This thesis examined these three aspects of cardiovascular c

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3

Alhaddad, Maath. "Cardiopulmonary manifestations in chronic obstructive pulmonary disease (COPD)." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/30008/.

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Rationale Chronic obstructive pulmonary disease (COPD) is a progressive lung condition with extrapulmonary manifestations- cardiovascular diseases (CVD), impaired physical function, activity and increased frailty. Integrating measures of function into community assessments is hindered by the space and time required. The association of function, activity and CVD has not been extensively investigated in COPD. Objectives Explore the potential utility of Time Up and Go (TUG) as a measure of physical function in COPD Assess association of non-invasive measures of haemodynamics to physical function

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4

Noell, Guillaume. "Multi-Level Integrated Analysis of Chronic Obstructive Pulmonary Disease (COPD) heterogeneity." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/667980.

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Non-Communicable Diseases (NCDs), including cancer, cardiovascular (heart diseases or stroke), respiratory (COPD or asthma) and metabolic diseases (diabetes) are chronic conditions that represent a major global health problem of the 21st century. All of them, however, are the end-result of a complex set of gene-environment interactions that develop over years and often lead to several NCDs co-existing in the same individual (multi-morbidity). Multi-level integrated analysis has the potential to uncover the heterogeneity of NCDs by conceptualizing them as emergent properties of a complex, no

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5

John, Michelle. "The extra-pulmonary effects of chronic obstructive pulmonary disease (COPD)." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14405/.

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Rationale Cardiovascular disease (CVD) is a leading cause of mortality in patients with COPD. Aortic stiffness, measured using aortic pulse wave velocity (PWV), an independent, non-invasive, predictor of CV risk; and inflammatory markers are increased in COPD. Screening tools for community based identification of increased CVD risk, and a proactive approach to addressing primary prevention of CVD is needed. Statins modulate aortic stiffness and are anti-inflammatory, but are not currently used for primary prevention in COPD. Objectives Proof of principle double-blind Randomised Control Trial (

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6

McPherson, E. A. "Equine chronic obstructive pulmonary disease (COPD) : publications 1974-1985." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/28607.

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7

Jones, Sharon Scardina. "Evaluating a Discharge Bundle for Chronic Obstructive Pulmonary Disease." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/4861.

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Acute exacerbation of chronic obstructive pulmonary disease (COPD) is one of the leading causes of hospital readmissions within 30 days. Frequent readmissions negatively affect hospital reimbursements and patient outcomes. Creative strategies, such as COPD care bundles, have been shown to reduce readmission rates according to existing studies. A COPD discharge bundle was developed and implemented at 1 community hospital in response to an identified problem with COPD readmissions. Evaluation of this quality improvement initiative was the purpose of this project study. The practice-focused quest

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8

Wadell, Karin. "Physical training in patients with chronic obstructive pulmonary disease - COPD." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-363.

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9

Bodduluri, Sandeep. "Analysis of chronic obstructive pulmonary disease (COPD) using CT images." Thesis, University of Iowa, 2012. https://ir.uiowa.edu/etd/2441.

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Chronic Obstructive Pulmonary Disease (COPD), a growing health concern, is the fourth leading cause of death in the United States. While people habituated to smoking constitute the highest COPD susceptible population, people exposed to air pollution or other lung irritants also form a major group of potential COPD patients. COPD is a progressive disease that is characterized by the combination of chronic bronchitis, small airway obstruction, and emphysema that causes an overall decrease in the lung elasticity affecting the

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10

Lewis, A. "Chronic Obstructive Pulmonary Disease (COPD) : patient experiences of COPD and pulmonary rehabilitation : an applied phenomenological study." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/349087/.

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Attendance at Pulmonary Rehabilitation (PR) in the UK is sub-optimal and reasons for this have been explored. However, Chronic Obstructive Pulmonary Disease (COPD) patient experiences have rarely been explored longitudinally through PR regardless of patient participation. Therefore, understanding sub-optimal attendance remains limited for the broad population who are referred. Furthermore, limited Primary Care PR research has been performed, where many programmes are run in the UK. This research aimed to explore COPD patient experiences before and after PR, whether they completed, did not atte

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11

Ravi, Arjun Kumar. "Macrophages, monocytes and interleukin-6 in chronic obstructive pulmonary disease." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/macrophages-monocytes-and-interleukin6-in-chronic-obstructive-pulmonary-disease(806db259-02de-4d50-8c2e-5b57cb2425c0).html.

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Background: COPD is associated with an increased lung macrophage burden. Whilst lung macrophages may self-renew, recruitment of peripheral blood monocytes from the systemic circulation is considered to represent their principal means of replenishment. Through modulating expression of monocytic chemokines CCL2/CCL3 and their respective receptors (CCR2/CCR1+CCR5), IL-6 could play a key role in facilitating the recruitment of monocytes to the lungs of COPD patients. COPD is associated with enhanced pulmonary and systemic IL-6 levels; concentrations of the soluble IL-6 receptor sIL-6R may be an im

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12

Lethbridge, Mark William. "The role of T cells in chronic obstructive pulmonary disease (COPD)." Thesis, King's College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407475.

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13

Johnson, Lorna Claire. "Respiratory and peripheral muscle with severe chronic obstructive pulmonary disease (COPD)." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420413.

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14

McGorum, Bruce C. "Studies on the aetiopathogenesis of equine chronic obstructive pulmonary disease (COPD)." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/30476.

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Inhalation challenges with antigenic extracts of <i>Micropolyspora faeni</i> and <i>Aspergillus fumigatus</i> induced pulmonary disease, similar to naturally occurring chronic obstructive pulmonary disease (COPD), only in COPD affected horses, implicating these agents in the aetiology of equine COPD. In this study, bronchoalveolar lavage fluid (BALF) cytology examination proved to be the most valuable technique for detecting pulmonary disease. Two methods for standardising the variable recovery of pulmonary epithelial lining fluid (PELF), in BALF, namely the urea and albumen dilution technique

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15

Collins, Peter Francis. "Nutritional screening and nutritional support in chronic obstructive pulmonary disease (COPD)." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/379646/.

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Malnutrition is a common problem in chronic obstructive pulmonary disease (COPD) and associated with poorer prognosis. Currently controversies surround the importance of nutritional intervention and how best to nutritionally manage those identified as at risk of malnutrition. Dietary advice (DA) and oral nutritional supplements (ONS) are two of the most common first line treatments for malnutrition in COPD but the evidence base for DA is lacking and for ONS appears uncertain. To date there have been no randomised trials comparing these two treatments in COPD. The aims of this thesis were three

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16

Pakhale, Smita. "Development and Validation of the new McGill COPD Quality of Life Questionnaire." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95663.

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Introduction: There is a need for a health-related quality of life questionnaire in COPD that fulfills the advantages of both, generic and disease-specific questionnaires. Objective: To finalize the development of a new, hybrid questionnaire (disease-specific items supplemented with items from the SF-36), the McGill COPD Quality of Life Questionnaire and to evaluate its psychometric properties (reliability, validity, responsiveness) in COPD subjects. [...]<br>Introduction: Il y a nécessité d'avoir accès à un questionnaire de qualité de vie qui pourrait offrir les avantages d'un questionnaire g

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17

Ubhi, Baljit Kaur. "A metabolomic study of chronic obstructive pulmonary disease (COPD) and its phenotypes." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608237.

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18

Brandén, Eva. "Chronic infection with Chlamydia pneumoniae in COPD and lung cancer." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-344-2/.

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19

Suh, Sooyeon. "STRESS, ANXIETY, AND HEART RATE VARIABILITY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1275495558.

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20

Arnardóttir, Ragnheiður Harpa. "Physical Training and Testing in Patients with Chronic Obstructive Pulmonary Disease (COPD)." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7632.

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<p>The overall aims of the studies were to investigate the effects of different training modalities on exercise capacity and health-related quality of life (HRQoL) in patients with moderate or severe COPD and, further, to explore two of the physical tests used in pulmonary rehabilitation.</p><p>In <b>study I</b>, the 12-minute walking distance (12MWD) did not increase on retesting in patients with exercise-induced hypoxemia (EIH) whereas 12MWD increased significantly on retesting in the non-EIH patients. In <b>study II</b>, we found that the incremental shuttle walking test was as good a predi

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21

Arnardóttir, Ragnheiður Harpa. "Physical training and testing in patients with chronic obstructive pulmonary disease (COPD) /." Uppsala : Acta Universitatis Upsaliensis, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7632.

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22

Haddad, Donna L. "Nutritional status indicators in hospitalized patients with chronic obstructive pulmonary disease (COPD)." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=67536.

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Malnutrition, as evidenced by low weight for height, low triceps skinfold thickness and low midarm muscle circumference, is prevalent among COPD patients. A stepped decline in nutritional status has been postulated as a mechanism for malnutrition wherein patients progressively suffer weight loss with each COPD exacerbation. A randomized clinical trial of continuous enteral nutrition could not successfully address whether or not the stepped decline in weight can be prevented. Despite this, sixteen patients admitted for a COPD exacerbation, participated in an observational prospective study wher

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23

Forslund, Linus, and Emil Sjödin. "Experiences of living with Chronic Obstructive Pulmonary Disease (COPD) : A literature review." Thesis, Umeå universitet, Institutionen för omvårdnad, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-161652.

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24

Kren, Erin McGuire. "Physical Activity and Veteran Status in Obesity and Chronic Obstructive Pulmonary Disease." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/4931.

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There are few data available regarding the relationship between physical activity and veteran status in those with combined chronic obstructive pulmonary disease (COPD) and obesity. COPD is a common illness and a leading cause of death in the United States. Veterans represent a distinct subpopulation in the United States and are more likely to have COPD, which is a disease with a high rate of comorbidities such as obesity. Physical activity can improve outcomes for those with COPD and obesity. However, recommendations for physical activity for those with COPD and obesity are vague. This study,

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25

Akiki, Zeina. "Biological Markers For Chronic Obstructive Pulmonary Disease And Asthma." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS081/document.

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L’étude des marqueurs biologiques dans la broncho-pneumopathie chronique obstructive (BPCO) et l'asthme, deux maladies respiratoires chroniques affectant des millions de personnes dans le monde, pourrait améliorer leur diagnostic, leur traitement et leur prévention.Cette thèse comprend deux parties. La première visait à évaluer l'association entre un marqueur spécifique des poumons, la protéine surfactant D (SP-D) sérique, et la BPCO, et à trouver un seuil de SP-D capable de discriminer les patients BPCO des témoins. Elle a été réalisée dans le cadre d’une étude cas-témoin au Liban incluant de

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26

Farooqi, Nighat. "Nutrition and energy expenditure in women with chronic obstructive pulmonary disease." Doctoral thesis, Umeå universitet, Lungmedicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-128680.

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Aim The overall objective of this thesis was to increase the knowledge and validate methods for assessment of total daily energy expenditure (TEE), energy requirement and energy intake (EI) in women with COPD. We also investigated the relationship of BMI with clinical characteristics of COPD in a population-based study. Due to the substantial and increasing morbidity in women with COPD, special attention was given to this group. Methods Resting metabolic rate (RMR) was measured by indirect calorimetry (IC). TEE was measured by criterion method, doubly labeled water (DLW) (Paper I-III) during a

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27

Higham, Andrew James. "The role of the liver X receptor in chronic obstructive pulmonary disease." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/the-role-of-the-liver-x-receptor-in-chronic-obstructive-pulmonary-disease(b1916ddb-6514-4407-b657-0dede8d7fa28).html.

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COPD is a condition characterised by chronic inflammation in which macrophages arethought to play a central role. Corticosteroids are the most widely used antiinflammatoryagents to treat COPD. There is a subset of inflammatory mediatorswhich are corticosteroid insensitive and so there is a need for novel anti-inflammatorytherapies to treat COPD. One such target is the liver X receptor (LXR), a cholesterolsensing nuclear hormone receptor with anti-inflammatory properties. Before investigating the anti-inflammatory potential of LXR, I aimed to validate thealveolar macrophage in vitro culture mod

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Machado, Stacey Jerrick. "Reducing 30-Day Readmission Rates in Chronic Obstructive Pulmonary Disease Patients." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6609.

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Early avoidable 30-day post discharge readmission among patients diagnosed with chronic obstructive pulmonary disease (COPD) is associated with poor transition care processes. The purpose of this project was to analyze organizational system processes for admission and discharge transition care of patients diagnosed with COPD to identify key intervention strategies that could decrease the rate of 30-day post-discharge readmission by 1%. The project used the transitional care model as the framework to target specific care transition needs and create patient-centered, supportive, evidence-based r

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29

Lytras, Theodoros 1987. "The Role of occupational exposures in Chronic Obstructive Pulmonary Disease." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/586017.

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Introduction: Occupational exposures are considered to be one of the newer and important risk factors for Chronic Obstructive Pulmonary Disease (COPD) besides tobacco smoking. However, the evidence mostly comes from smaller and cross-sectional studies and important questions remain unanswered, such as which specific exposures are responsible, the magnitude of the risk involved, and how the risk varies between men and women and between smokers and nonsmokers. The aim of this thesis was to examine the association between objectively assessed occupational exposures and changes in COPD-related out

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30

Jantarakupt, Peeranuch. "The experience of men who were managing symptoms of COPD." Diss., Columbia, Mo. : University of Missouri-Columbia, 2005. http://hdl.handle.net/10355/5814.

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Thesis (Ph. D.)--University of Missouri-Columbia, 2005.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Vita. "May 2005" Includes bibliographical references.

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31

Mantoani, Leandro Cruz. "Role of physical activity in daily life in Chronic Obstructive Pulmonary Disease (COPD)." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31402.

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Background: Chronic obstructive pulmonary disease (COPD) is an important common chronic lung condition that is a leading cause of morbidity and mortality worldwide, resulting in a substantial and increasing economic and social burden to health care systems. Physical activity (PA) is the strongest predictor of mortality in this population, playing an important role determining the quality of life in COPD, with better outcomes being reported by those who have higher levels of PA. Therefore, improving PA levels has been considered a key component in the management of patients with COPD. Likewise,

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32

Hodson, Matthew. "Development of a patient reported experience measure in chronic obstructive pulmonary disease (COPD)." Thesis, University of Portsmouth, 2014. https://researchportal.port.ac.uk/portal/en/theses/development-of-a-patient-reported-experience-measure-in-chronic-obstructive-pulmonary-disease-copd(c7bf6540-155f-4245-b764-daa61ea6f73a).html.

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The experience of patients living with chronic obstructive pulmonary disease (COPD) and their views on the quality of healthcare they receive is not currently captured in patient reported measures. Aim: To develop and validate a patient reported experience measure to assess experiences of living with COPD and perceived quality of healthcare provision. Method: Previous work with 83 COPD patients identified 38 items for inclusion in a patient reported experience measure. These, together with the COPD Assessment Test and Hospital Anxiety and Depression Scale were administered to patients with COP

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33

Brozyna, Sheree. "The role of chemokines and chemokine receptors in chronic obstructive pulmonary disease (COPD) /." Title page and abstract only, 2005. http://web4.library.adelaide.edu.au/theses/09SB/09sbb8859.pdf.

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34

Kumar, Manish [Verfasser]. "Senescence, DNA damage and repair in chronic obstructive pulmonary disease (COPD) / Manish Kumar." Gießen : Universitätsbibliothek, 2014. http://d-nb.info/1068772697/34.

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35

Al-Khdour, Maher Rateb. "An integrated disease and medicines management programme for patients with chronic obstructive pulmonary disease (COPD)." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501233.

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36

Shaw, I., JM Loots, L. Lategan, and BS Shaw. "Effectiveness of aerobic exercise training in improving pulmonary function in asthmatics." African Journal for Physical, Health Education, Recreation and Dance, 2009. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1001698.

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ABSTRACT Asthma exemplifies a major medical concern and is a considerable cause of morbidity and mortality in Western society. Controversy still exists regarding the most effective mode and intensity of exercise training for asthmatics. Thus, the purpose of the study was to determine whether walking or jogging at 60% of age-predicted heart rate maximum can increase effort-dependent pulmonary function parameters in moderate, persistent asthmatics. Forty-four sedentary asthmatics were randomly assigned to either a non-exercising control (NE) group (n = 22) or an eight-week moderate-intensity aer

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37

Hallin, Runa. "Nutritional Depletion in Chronic Obstructive Pulmonary Disease (COPD) : Effect on Morbidity, Mortality and Physical Capacity." Doctoral thesis, Uppsala universitet, Institutionen för medicinska vetenskaper, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9512.

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The overall aim of this work was to examine the effects of depleted nutritional status on some aspects of Chronic Obstructive Pulmonary Disease (COPD). Morbidity. In paper І, we found that energy intake was lower than the calculated energy demand for all patients. A low body mass index (BMI) at inclusion and weight loss, during the one year follow-up period were independent risk factors for having a new exacerbation (p = 0.003 and 0.006, respectively). Mortality. Nineteen percent of the patients in paper ІІ, where underweight (BMI<20). A significant positive correlation was found between BM

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Sohanpal, Ratna. "Understanding the reasons for non-participation in self-management interventions amongst patients with chronic conditions : addressing and increasing opportunities for patients with advanced chronic obstructive pulmonary disease to access self-management." Thesis, Queen Mary, University of London, 2015. http://qmro.qmul.ac.uk/xmlui/handle/123456789/15031.

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Background: In chronic obstructive pulmonary disease (COPD), understanding the problem of poor patient participation in evidence-based self-management (SM) and pulmonary rehabilitation (PR) programmes (together referred to as SM support programmes) is critical. This thesis aimed to improve understanding of poor patient participation and retention in these programmes; how participation might be improved; and how might patients be better supported with their SM. Methods: Using the Medical Research Council guidance on complex interventions this thesis (1) quantified the 'actual' patient participa

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Ramis, Cabrer Daniel 1993. "From chronic obstructive pulmonary disease to lung cancer : an immunologic approach." Doctoral thesis, Universitat Pompeu Fabra, 2019. http://hdl.handle.net/10803/667310.

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Se ha establecido que un subconjunto de pacientes con cáncer debuta con infiltrados inmunes que se organizan en agregados en el nicho tumoral y sus alrededores. Estas estructuras linfoides se desarrollan en respuesta a estímulos inflamatorios a través de un proceso estrechamente regulado. Además de su valor pronóstico, las TLSs pueden representar una nueva vía para las estrategias terapéuticas, pero actualmente se encuentra en etapas iniciales. En contraste con el papel en la activación inmune de las TLSs, en ciertos tumores, su efecto puede apuntar hacia la progresión tumoral como con

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Chatila, Wissam M. F. "MicroRNA Expression in Regulatory T Cells in Chronic Obstructive Pulmonary Disease." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/333572.

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Microbiology and Immunology<br>Ph.D.<br>COPD is characterized by an abnormal regulatory T cell (Treg) response with a shift towards a Th1 and Th17 cell responses. However, it is unclear if the function of Treg cells is impaired by smoking and in COPD. In addition, the miRNA profile of Treg cells in COPD is unknown and whether miRNA deregulation contributes to COPD immunopathogenesis. We set the objective to study Treg cell function isolated from peripheral blood of patients with COPD versus controls and to compare their miRNA profiles. We also were interested in exploring the function of some

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Stone, Ian. "Effects of COPD and its treatment on cardiovascular structure and function assessed through advanced imaging techniques." Thesis, Queen Mary, University of London, 2016. http://qmro.qmul.ac.uk/xmlui/handle/123456789/23199.

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Significant cardiovascular morbidity and mortality exists in chronic obstructive pulmonary disease independent of traditional risk factors. A number of different hypotheses exist to explain this association including the contribution arterial stiffness and lung hyperinflation. Non-invasive cardiovascular imaging and assessment are ideal methods through which this relationship can be further studied although a number of the techniques have yet to be validated in COPD. In this thesis we aimed to achieve a number of goals. First, we aimed to assess the reproducibility and level of agreement betwe

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Tatari, Wisam. "Using Pharmacist-Led Tele-Consultation to Review Patients with Chronic Obstructive Pulmonary Disease." Thesis, University of Bradford, 2018. http://hdl.handle.net/10454/17311.

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Bhunthurat, Anurak. "The Vitamin B-6 Status of Patients with Chronic Obstructive Pulmonary Disease." Thesis, North Texas State University, 1986. https://digital.library.unt.edu/ark:/67531/metadc500541/.

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The problem of this study is to determine the vitamin B-6 status of patients who have chronic obstructive pulmonary disease (COPD). Erythrocyte aspartate transaminase assay was the method for measuring vitamin B-6 status. The vitamin B-6 status was examined in thirty subjects (ten COPD subjects and twenty control subjects). An unpaired t-test was used to compare the vitamin B-6 status of the COPD group versus the control group. Four determinants (percentage stimulation, ratio of basal to stimulated activity, basal activity, and stimulated activity) were used to determine vitamin B-6 status in

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Pang, Yu. "Human Anti-Histone 3.3 Antibodies as Potential Biotherapeutics for Chronic Obstructive Pulmonary Disease (COPD)." Master's thesis, Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/378762.

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Pharmaceutical Sciences<br>M.S.<br>Chronic Obstructive Pulmonary Disease (COPD), which is characterized by limitation of pulmonary air flow, is now the third major cause of death worldwide. Barrero et al. have reported that the elevation of extracellular hyperacetylated histone H3.3 in the lungs of COPD patients is associated with cytotoxicity and disease progression. They found that extracellular hyperacetylated H3.3 was cytotoxic to lung structural cells and resistant to proteasomal degradation, and that mouse antibodies to either the C- or N- termini of H3.3 could partially reverse H3.3 tox

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Donaire, Gonzalez David. "Measure and effects of physical activity in patients with Chronic Obstructive Pulmonary Disease (COPD)." Doctoral thesis, Universitat Ramon Llull, 2015. http://hdl.handle.net/10803/347216.

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Antecedents: La Malaltia Pulmonar Obstructiva Crònica (MPOC) és una de les principals causes de mortalitat i discapacitat a nivell mundial. L'activitat física és un dels pocs factors modificables que desacceleren l'evolució de la MPOC. No obstant, la dosi i les característiques de l'activitat física responsables de la desacceleració són encara desconegudes. En conseqüència, els objectius d'aquesta tesi són avançar i perfeccionar la metodologia i els instruments per avaluar l'activitat física realitzada pels malalts amb MPOC, aprofundir en el coneixement sobre les característiques i els patrons

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McCafferty, John. "Respiratory heat and moisture loss in health, asthma and chronic obstructive pulmonary disease (COPD)." Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/29259.

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It was hypothesized that Respiratory heat and moisture loss (RHML) would be altered in patients with Asthma and Chronic obstructive pulmonary disease (COPD) due to the effects of airway inflammation and re-modeling. By designing a novel device incorporating humidity, temperature and flow sensors, RHML was measured in 25 normal controls, 33 asthmatics and 17 patients with COPD. In normal subjects RHML was found to be dependent on breathing pattern as defined by tidal volume and minute ventilation whereas no association was found between RHML and body surface area. At matched breathing patterns

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47

Reavell, Colleen Frances. "Resolution of muscle wasting during an acute exacerbation of chronic obstructive pulmonary disease (COPD)." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0031/MQ64435.pdf.

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48

Lindberg, Anne. "Chronic obstructive pulmonary disease (COPD) : prevalence, incidence, decline in lung function and risk factors." Doctoral thesis, Umeå : Public Health and Clinical Medicine, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-347.

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49

Ng, Li Whye Cindy. "Evaluation and optimisation of physical activity in individuals with chronic obstructive pulmonary disease (COPD)." Thesis, Curtin University, 2014. http://hdl.handle.net/20.500.11937/186.

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The studies in this thesis evaluated the physical activity (PA) in individuals with chronic obstructive pulmonary disease (COPD), identified strategies to optimise PA, determined the effects of a supervised walking training program on performance during the endurance shuttle walk test (ESWT) and determined the minimal detectable difference for the ESWT.The measurement techniques used included: PA using motion sensors; HRQoL assessment; Fear of Falling Questionnaire, Hospital Anxiety and Depression Scale; and functional exercise testing.

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50

Janaudis-Ferreira, Tania. "Strategies for exercise assessment and training in patients with chronic obstructive pulmonary disease." Doctoral thesis, Umeå universitet, Sjukgymnastik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-35565.

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Rationale: Chronic obstructive pulmonary disease (COPD) is not only a common lung disease but is a major cause of morbidity and mortality worldwide. Pulmonary rehabilitation (PR) helps optimize function and independence by increasing exercise capacity, reducing symptoms and improving health related quality of life (HRQL). Exercise training is certainly a key component of the PR programs; however, many of its aspects still need to be better defined such as optimal exercise assessment and training modality for these patients. The general purpose of this thesis was to generate new knowledge that

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