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Journal articles on the topic 'The compound'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Journal, Baghdad Science. "SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME (2-AMINO-5-THIOL-1, 3, 4-THIADIAZOLE DERIVATIVES." Baghdad Science Journal 4, no. 1 (2007): 89–94. http://dx.doi.org/10.21123/bsj.4.1.89-94.

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Five derivatives of thiadiazole were prepared with aldehydes and alkyl halides, compoundA: 2-amino-5-thiol-1,3,4- thiadiazole, compound B :2-(o-hydroxybenzylidine)amino-5-thiol-1,3,4-thiadiazole, compoundC: 2(2-butan-lidine)amino-5-thiol-1,3,4-thiadiazole, compound E: 2- amino-5-(2-Propanylthio)-1,3,4-thiadiazol) and compound F:2(o-chlorobenzylamino)-5-(2-propanyl thio)-1,3,4 thiadiazol. All prepared compounds were diagnosed by (IR) and (UV) Spectroscopy. All of those compounds were screened for their anti-microbial activity in vitro. The results show that most of the compounds A, B, C exhibit

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Mageed, Fatimah Abdul Razzak, Zena T. Omran, and Shatha Abd Al-Jabbar. "Preparation and Characterization of a New Polymer for Mesalazine and Study of its Biological Activity against Colon Cancer." Cognizance Journal of Multidisciplinary Studies 5, no. 1 (2025): 139–46. https://doi.org/10.47760/cognizance.2025.v05i01.011.

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This work produced new homogenous and heterogeneous polymers with medical qualities to expand the controlled drug, as well as new drug-substituted monomers. The following three lines were included in this work: Preparation is the first stage (compound1) via reaction of furan-2,5-dione with 4-aminobenzoic acid, then compound (1) was reacted with amino drug such as (mesalazine) compound(2) monomer. Second line: The homogeneous polymer (compound 3) was produced by employing MEKP as an initiator in the polymerase reaction of the monomer's (compound 2) free radicals under nitrogen. Third line: Usin

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Fatimah, Abdul Razzak Mageed, T. Omran Zena, and Abd Al-Jabbar Shatha. "Preparation and Characterization of a New Polymer for Mesalazine and Study of its Biological Activity against Colon Cancer." Cognizance Journal of Multidisciplinary Studies (CJMS) 5, no. 1 (2025): 139–46. https://doi.org/10.47760/cognizance.2025.v05i01.011.

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This work produced new homogenous and heterogeneous polymers with medical qualities to expand the controlled drug, as well as new drug-substituted monomers. The following three lines were included in this work:<strong> </strong>Preparation is the first stage (compound1) via reaction of furan-2,5-dione with 4-aminobenzoic acid, then compound (1) was reacted with amino drug such as (mesalazine) compound(2) monomer.<strong> </strong>Second line: The homogeneous polymer (compound 3) was produced by employing MEKP as an initiator in the polymerase reaction of the monomer's (compound 2) free radical

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Kádár, György. "Is There A Reason for the Existence of An independent Finno-Ugric Musicology?" Folklore: Electronic Journal of Folklore 23 (2003): 86–106. http://dx.doi.org/10.7592/fejf2003.23.compound.

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Libben, Gary, Mira Goral, and R. Harald Baayen. "What does constituent priming mean in the investigation of compound processing?" Mental Lexicon 13, no. 2 (2018): 269–84. http://dx.doi.org/10.1075/ml.00001.lib.

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Abstract Most dictionary definitions for the term compound word characterize it as a word that itself contains two or more words. Thus, a compound word such as goldfish is composed of the constituent words gold and fish. In this report, we present evidence that compound words such as goldfish might not contain the words gold and fish, but rather positionally bound compound constituents (e.g., gold- and -fish) that are distinct and often in competition with their whole word counterparts. This conceptualization has significant methodological consequences: it calls into question the assumption th

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Hu, Yanmei, Megan Keniry, Stephanie O. Palmer, and James M. Bullard. "Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa." Antimicrobial Agents and Chemotherapy 60, no. 8 (2016): 4820–29. http://dx.doi.org/10.1128/aac.00800-16.

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ABSTRACTBacterial protein synthesis is the target for numerous natural and synthetic antibacterial agents. We have developed a poly(U) mRNA-directed aminoacylation/translation (A/T) protein synthesis system composed of phenylalanyl-tRNA synthetases (PheRS), ribosomes, and ribosomal factors fromPseudomonas aeruginosa. This system has been used for high-throughput screening of a natural-compound library. Assays were developed for each component of the system to ascertain the specific target of inhibitory compounds. In high-throughput screens, 13 compounds were identified that inhibit protein syn

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Cheng, Xueheng, Bing Yan, Lan Gao, et al. "Compound Transfer Efficiency from Polystyrene Surfaces: Application to Microarrayed Compound Screening." Journal of Biomolecular Screening 10, no. 4 (2005): 293–303. http://dx.doi.org/10.1177/1087057104272498.

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In microarrayed compound screening (μARCS), compounds are spotted and dried onto a polystyrene sheet (ChemCard)ata high density and introduced into the assay by contacting with agarose gels that contain reagents for the assay. The authors have conducted studies to characterize the compound transfer process using 59 compounds of diverse properties. The amount of compounds remaining on the ChemCard was determined by liquid chromatography/mass spectrometry after incubation with agarose gels for predetermined time periods. The results showed good correlation with kinetics of compound transfer to p

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Jarallah, Aziz Latif, Khalid Fahad Ali, Raied Mustafa Shakir, and Shaimaa Abed Saoud. "Synthesis, Antibacterial and Antifungal Activities for Novel Derivatives of 2,2'-(((1-benzylbenzoimidazol-2-yl)methyl)azanediyl)bis(ethan-1-ol)." Ibn AL- Haitham Journal For Pure and Applied Science 32, no. 1 (2019): 56. http://dx.doi.org/10.30526/32.1.1966.

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The compound 2,2'-(((1H-benzo(d)imidazol-2-yl)methyl)azanediyl)bis(ethan-1-ol) was reacted with benzyl bromide to afford compound (1) which used as row material to prepare a series of compounds through condensation reaction, the starting compound were reacted with tosyl chloride to protect the OH group to afford compound 2, then reacted benzyl bromide to produce compound (2), then the compound (2) treated with three compounds ( 2-mercaptobenzthiazole, 2-mercaptobenimidazol and 2-chloromethyl benzimidazole) to form compounds 3a,b, 4a,b and 5a,b respectively. In the another step the click reacti

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Jacky, (Yibu Luo), and (Junjie Ma) Martin. "A Brief Analysis of Chinese Compound Features." INTERNATIONAL JOURNAL OF SOCIAL SCIENCE, INNOVATION AND EDUCATIONAL TECHNOLOGIES (ONLINE) - ISSN: 2717-7130 1, no. 3 (2020): 311–15. https://doi.org/10.5281/zenodo.3977179.

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As Booij (2016) stated, morphology refers to the study of the “internal structure of words” and the rules by which words are formed (p. 7) 0. As a significant branch of morphology, English speakers are accustomed to composing a compound phrase with several single lexemes or free morphemes. As a ubiquitous linguistic phenomenon, compounds have become an indispensable component of language lexeme formation. Compounds, by definition, are “words that are composed of two (or more) bases, roots, or stems” (Lieber, 2010, p. 43). In Mandarin Chinese, almost all words can be con

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Gomes, Ligia R., John N. Low, Alan B. Turner, Alexander W. Nowicki, Thomas C. Baddeley, and James L. Wardell. "Crystal structures and Hirshfeld surface analyses of a des-A-B-aromatic steroidal compound, and two of its derivatives, having a trans-2,3,4,5-tetrahydro-3a-methyl-7-methoxybenz[e]indane skeleton – structural comparisons with reported tetrahydrobenz[e]indene derivatives." Zeitschrift für Naturforschung B 74, no. 9 (2019): 649–63. http://dx.doi.org/10.1515/znb-2019-0094.

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AbstractThe crystal structures and Hirshfeld surface analyses of the des-A-B-aromatic steroid derivative, (3a,9b)-1,2,3a,4,5,9b-hexahydro-7-methoxy-3a-methyl-3H-benz[e]-inden-3-one (or 5-methoxy-des-A-estra-5,7,9-triene-17-one) 1, its acetohydrazide derivative, 2, and its hydrazone derivative, 3, are reported. All three compounds crystallize in chiral space groups: compounds 1 and 2 in the orthorhombic space group P212121 each with one molecule in the asymmetric unit, and compound 3 in the monoclinic space group P21 with two similar but independent molecules, Mol A and Mol B, in the asymmetric

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Faridah, Shirly Kumala, Gumilar Adhi Nugroho, and Partomuan Simanjuntak. "Study of Potential Antiobesity Compounds from Amylchlorogenate Derivates on Leptin Hormone and their Toxicity using Molecular Docking Approach." Journal of Natural Product for Degenerative Diseases 1, no. 2 (2024): 67–79. http://dx.doi.org/10.58511/jnpdd.v1i2.6070.

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Chlorogenic acid, a type of phenolic acid, is a polar compound that has anti-obesity effects with unclear mechanisms. This study aims to obtain compounds that are active as antiobesity, their interaction with receptors and its toxicity. This research was carried out in several steps, internal validation of targets and methods using Yasara, docking of test compounds and positive control using PLANTs, interaction visualization using Pymol and toxicity testing using Protox-II. Validation results show four receptors and test method meet the requirements. Docking results of setmelanotide on recepto

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Li, Hong Zheng, He Zhou, and Yao Hong Jin. "A Method for Identifying V+N Compound Nouns in Patent Machine Translation." Applied Mechanics and Materials 513-517 (February 2014): 4617–20. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.4617.

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In this paper, we introduced one kind of special compound noun in Chinese patent texts composed of verb and noun, and presented a rule-based method for Chinese-English patent Machine Translation (MT) to improve the identification of compound nouns, with the purpose of decreasing the possibilities that verbs may disturb the identification of core predicate verb. The system first tagged different weights on verbs then determined the properties of verbs and recognized the compounds according to the weights. We then conducted experiments with the method, which proved that the method could identify

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BENCZES, RÉKA. "Repetitions which are not repetitions: the non-redundant nature of tautological compounds." English Language and Linguistics 18, no. 3 (2014): 431–47. http://dx.doi.org/10.1017/s1360674314000112.

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In English morphological literature, the term ‘tautological compound’ has been typically used to refer to two distinct – but closely related – phenomena: (1) compounds composed of a hyponym and a superordinate term (such as oak tree); and/or (2) compounds based upon two synonymous units (such as subject matter). Such combinations are one of the quirkiest – and least researched – phenomena of English compounding. Their oddity can be attributed to two main factors. First, as their name, ‘tautological compound’ implies, at face value such combinations can be considered as prime examples of the re

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Guoyong, Mao, Liu Runzhan, and Zhang Ning. "A network study of chemical relations: From elements to polynary compounds." Chemistry International 8, no. 4 (2022): 130–35. https://doi.org/10.5281/zenodo.7115552.

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The chemical compounds are composed of elements of different numbers. So far, more than 100 million compounds made up of 103 elements have been discovered. The aim of this study is to investigate the relation between compounds that have different number of elements. Using compounds extracted from a famous website (ignoring the stoichiometric of elements), we found that for compounds with <em>n</em> elements, <em>n-1</em> elements in this compound can form at least one compound that has <em>n-1</em> elements, suggesting that compounds with lower number of elements are foundations of compounds w

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Bús, Csaba, Norbert Kúsz, Gusztáv Jakab, et al. "Phenanthrenes from Juncus Compressus Jacq. with Promising Antiproliferative and Anti-HSV-2 Activities." Molecules 23, no. 8 (2018): 2085. http://dx.doi.org/10.3390/molecules23082085.

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Juncaceae species are rich sources of phenanthrenes. The present study has focused on the isolation and structure determination of biologically active components from Juncus compressus. Eleven compounds (nine phenanthrenes and two flavonoids) have been isolated from the plant by the combination of different chromatographic methods. Two compounds (compressins A (Compound 1) and B (Compound 2)) are novel natural products, while seven phenanthrenes (effusol (Compound 3), effususol (Compound 4), juncusol (Compound 5), 2-hydroxy-1-methyl-4-oxymethylene-5-vinyl-9,10-dihydrophenanthrene (Compound 6),

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16

Asamiya, Yuki, Takahiro Yamada, and Hisanori Yamane. "Synthesis and Characterization of NaCd0.92Sn1.08, Na(Cd0.28Sn0.72)2 and Na2CdSn5 with Three-Dimensional Cd-Sn Frameworks." Inorganics 9, no. 3 (2021): 19. http://dx.doi.org/10.3390/inorganics9030019.

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The crystal structures of three new ternary compounds, NaCd0.92Sn1.08 (I), Na(Cd0.28Sn0.72)2 (II), and Na2CdSn5 (III) synthesized in a sodium-cadmium-tin system were determined by single-crystal X-ray analysis to be the following: (I) LiGeZn-type structure (hexagonal, a = 4.9326(1) Å, c = 10.8508(3) Å, space group P-6m2); (II) CaIn2-type structure (hexagonal, a = 4.8458(2) Å, c = 7.7569(3) Å, P63/mmc); and (III) isotype with tI-Na2ZnSn5 (tetragonal, a = 6.4248(1) Å, c = 22.7993(5) Å, I-42d). Each compound has a three-dimensional framework structure mainly composed of four-fold coordinated Cd a

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He, Han Wei, Xiao Wang та Deng Yu Pan. "Study of Preparing β''-Alumina by Solid-State Synthesis". Advanced Materials Research 1004-1005 (серпень 2014): 533–37. http://dx.doi.org/10.4028/www.scientific.net/amr.1004-1005.533.

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In this paper, β''-alumina powders were prepared by solid-state synthesis method with different kinds of sodium compounds such as sodium carbonate, sodium bicarbonate, sodium oxalate, sodium acetate and sodium citrate. Each sodium compound was mixed with α-alumina by ball-milling, and then dried and calcined in muffle furnace, respectively. In order to confirm the superior condition for different sodium compound to prepare β''-alumina, original raw material with different powders molar ratio and calcination temperature were applied. The phase compositions of mixed powders after calcination wer

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Bowes, Scott, Dongyu Sun, Azita Kaffashan, et al. "Quality Assessment and Analysis of Biogen Idec Compound Library." Journal of Biomolecular Screening 11, no. 7 (2006): 828–35. http://dx.doi.org/10.1177/1087057106290993.

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A subset of the compound repository for lead identification at Biogen Idec was characterized for its chemical stability over a 3-year period. Compounds were stored at 4 °C as 10 mM DMSO stocks, and a small subset of compounds was stored as lyophilized dry films. Compound integrity of 470 discrete compounds (Compound Set I) and 1917 combinatorial chemistry-derived compounds (Compound Set II) was evaluated by liquid chromatography/mass spectrometry from the time of acquisition into the library collection and after 3 years of storage. Loss of compound integrity over the 3 years of storage was obs

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Muhammad Irsyad Hamid Nugroho, Gita Bintang Aulia, Listiana Pramudita, et al. "Kualitas Isi dan Penggunaan Kalimat Majemuk pada Buku Antologi Cerpen Berjudul “Rinduku Sederas Hujan Sore Itu” Penerbit Noura Books Publishing sebagai Sumber Bacaan Siswa Kelas 12 SMA." Atmosfer: Jurnal Pendidikan, Bahasa, Sastra, Seni, Budaya, dan Sosial Humaniora 2, no. 4 (2024): 57–79. https://doi.org/10.59024/atmosfer.v2i4.1013.

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This research is motivated by the quality of content and compound sentences. A compound sentence is a sentence that has two or more subordinate clauses connected by a conjunction. Compound sentences with several types will expand the scope of analysis in this research. These types include equivalent compounds, multilevel compounds, dense compounds, expanded compounds, and mixed compounds. However, our team's analysis was limited to three compound sentences, namely equivalent compound sentences (coordinative compound sentences), graded compound sentences (subordinating compound sentences), and

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Izka, Riska Agustina, Nur Isnainiyah Nur, and Rulik Setiani Rulik. "An Analysis of Compound Words on Culinary and Cooking Terms in MasterChef Indonesia Program from Top 5 until Grand Final Session 7." Griya Cendikia 8, no. 1 (2023): 463–75. http://dx.doi.org/10.47637/griyacendikia.v8i1.316.

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ABSTRACTMorphology is a field of linguistics that studies the formation of words or morphemes in a language. One of the developments of a language is word formation by combining two or more existing words to create new meanings. The word formation in this case is called compound words. In studying linguistics, there is certainly encounter a lot of foreign terms, and one of the terms may include compound words. Therefore, some words may sound foreign to the general public. In the process of learning compound words, there is can use this as a learning medium to modify boring learning strategies

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Yunrong, Ren, Xu Ya, Sun Zuqing, and Chen Guoliang. "Site Occupation of Ternary Element in an Alti Compound by Alchemi." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 2 (1990): 418–19. http://dx.doi.org/10.1017/s0424820100135691.

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Site occupation of alloying additions in AlTi compounds is important for high temperature alloys development. In this paper, we intend to locate the ternary element Nb in an AITi compound using the ALCHEMI technique. With the L10_type structure, the planes of either (110) or (001) are composed of Al and Ti atoms alterately. Therefore, the ternary element dissolved in the AITi compound can be easily located by ALCHEMI technique[1,2].A Specimen of 51.1 at%Al-41.5at%Ti-7.4at%Nb alloy was used. The structure of this specimen is composed of AlTi, Ti3Al, and other intermetallic compounds which were

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Mousavi, Seiedeh Negar, Davood Nori-Shargh, Hooriye Yahyaei, and Kobra Mazrae Frahani. "Complete basis set, hybrid-density functional theory study, and natural bond orbital interpretations of the conformational behavior of halocarbonyl, thiocarbonyl, and selenocarbonyl isocyanates." Canadian Journal of Chemistry 90, no. 4 (2012): 333–43. http://dx.doi.org/10.1139/v2012-002.

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Complete basis set CBS-QB3, hybrid-density functional theory (B3LYP/Def2-TZVPP) based methods and NBO interpretation were used to investigate the impacts of the stereoelectronic effects and electrostatic and steric interactions on the conformational properties of halocarbonyl isocyanates (halo = F (1), Cl (2), and Br (3)), halothiocarbonyl isocyanates (halo = F (4), Cl (5), and Br (6)), and haloselenocarbonyl isocyanates(halo = F (7), Cl (8), and Br (9)). Both methods showed that the Z-conformations of compounds 1, 4, and 7 are more stable than their corresponding E conformations, but the stab

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Yang, Jian, Yongtian Zhao, Jun Wan, et al. "Synthesis and Biological Evaluation of Novel Benodanil-Heterocyclic Carboxamide Hybrids as a Potential Succinate Dehydrogenase Inhibitors." Molecules 25, no. 18 (2020): 4291. http://dx.doi.org/10.3390/molecules25184291.

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In order to discover new antifungal agents, twenty novel benodanil-heterocyclic carboxamide hybrids were designed, synthesized, and characterized by 1H NMR and HRMS. In vitro, their antifungal activities against four phytopathogenic fungi were evaluated, as well as some of the target compounds at 50 mg/L demonstrated significant antifungal activities against Rhizoctonia solani. Especially, compounds 17 (EC50 = 6.32 mg/L) and 18 (EC50 = 6.06 mg/L) exhibited good antifungal activities against R. solani and were superior to the lead fungicide benodanil (a succinate dehydrogenase inhibitor, SDHI)

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Kuswoyo, Heri, and Eva Tuckyta Sari Sujatna. "“Economy Struggle to Escape Coronacoma”: Compound Word Formation Processes of COVID-19 Related Terms in Online English News Articles." Theory and Practice in Language Studies 13, no. 4 (2023): 957–64. http://dx.doi.org/10.17507/tpls.1304.17.

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This study aimed to uncover the types of compound word formation and how the compound word formation processes of related new terms in the COVID-19 pandemic's online English news articles were formed. This study used Lieber (2009) and Plag’s (2002) compound word formation frameworks. The data were obtained from ten news articles related to the COVID-19 pandemic using a qualitative descriptive method. The results showed that there were so varied types of the derivation of compound word processes, namely coordinative, subordinative, and attributive. Meanwhile, based on the stress of compound, th

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Jang, Gwanghoon, Sungjoon Park, Sanghoon Lee, Sunkyu Kim, Sejeong Park, and Jaewoo Kang. "Predicting mechanism of action of novel compounds using compound structure and transcriptomic signature coembedding." Bioinformatics 37, Supplement_1 (2021): i376—i382. http://dx.doi.org/10.1093/bioinformatics/btab275.

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Abstract Motivation Identifying mechanism of actions (MoA) of novel compounds is crucial in drug discovery. Careful understanding of MoA can avoid potential side effects of drug candidates. Efforts have been made to identify MoA using the transcriptomic signatures induced by compounds. However, these approaches fail to reveal MoAs in the absence of actual compound signatures. Results We present MoAble, which predicts MoAs without requiring compound signatures. We train a deep learning-based coembedding model to map compound signatures and compound structure into the same embedding space. The m

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Tolba, Mahmoud S., Mostafa Sayed, Shaban A. A. Abdel-Raheem, Taher A. Gaber, Adel M. Kamal El-Dean, and Mostafa Ahmed. "Synthesis and spectral characterization of some new thiazolopyrimidine derivatives." Current Chemistry Letters 10, no. 4 (2021): 471–78. http://dx.doi.org/10.5267/j.ccl.2021.4.004.

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Thiazolopyrimidnes are considered one of the most interesting classes in heterocyclic chemistry due to their pharmaceutical importance. Herein, we report the synthesis of some new heterocyclic compounds containing thiazolopyrimidine starting from compound (1) which was previously prepared in literature. The starting compound was allowed to react with different alkylating agents such as chloroacetone, chloroacetyl chloride, and phenacyl bromide to afford derivatives (2-4). Compound (5), benzylidene derivative, was obtained by the reaction of compound (2) with benzaldehyde while amino-dicarbonit

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Hamid Mohammed Saleh Al-Jubori. "Synthesis And Identification Of from HEMA Schiff Base Derivatives Contains Aldehyde Group For Hexa and Hepta Cyclization." Tikrit Journal of Pure Science 22, no. 1 (2023): 83–94. http://dx.doi.org/10.25130/tjps.v22i1.612.

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In this research the polymer which contains aldehyde group [H1] has been prepared by oxidation [H] using the oxidizing agent (Dess Martin Periodinane), [H1] has been dialyzed by ethanol, Schiff bases[H2,H5andH8] compounds have been prepared through the reaction of compound [H1] with appropriate amines, [H3] compound which contains hydroquinazolin ring has been prepared by the reaction of [H2] compound with 2-amino benzoic acid.[H4]which has been prepared by cyclization reaction of compound [H2] with phthalic anhydride. compounds [H6,H7]were prepared by the reaction of [H5] compound with 2-amin

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Adikayon, Leonilla Yolanda Kintan. "Compound words on the Jakarta post newspaper and Việtnam news newspaper". Journal of Applied Studies in Language 4, № 2 (2020): 260–72. http://dx.doi.org/10.31940/jasl.v4i2.2107.

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A newspaper has become the major news source around the world, either the printed or online newspaper. A newspaper provides many kinds of news and from different perspectives. Words in the newspaper play a significant role to deliver the information to the readers. The morpho-semantic study is needed to find out the uncommon words and their meaning in the newspaper. News in The Jakarta Post newspaper and Việt Nam News newspaper were analyzed, applying Hamawand’s (2001) compound categorization. Endocentric compound and exocentric compound by O’Grady et al (2016) are also being used in this stud

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El-Bialy, Rowan, Christina L. Gagné, and Thomas L. Spalding. "Processing of English compounds is sensitive to the constituents’ semantic transparency." Mental Lexicon 8, no. 1 (2013): 75–95. http://dx.doi.org/10.1075/ml.8.1.04elb.

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Compounds vary in terms of the extent to which the constituents’ meanings contribute to the meaning of the compound, and there is an ongoing debate about whether the semantic representations of the constituents of opaque compounds are available during compound processing. Three lexical decision experiments investigated whether semantically priming the first constituent of a compound influenced the processing of that compound. Experiment 1 found semantic priming for fully transparent (TT) compounds but not for OT compounds. Experiment 2 found semantic priming for TT compounds, but not for TO co

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Liu, Chao, Weiwei Zhang, and Gaigai Cai. "Synthesis, Crystal Structures and Catalytic Activities of Two Copper Coordination Compounds Bearing an N,N’-Dibenzylethylenediamine Ligand." Crystals 10, no. 6 (2020): 528. http://dx.doi.org/10.3390/cryst10060528.

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Two copper coordination compounds bearing an N,N’-dibenzylethylenediamine ligand, namely [Cu3L(CH3COO)6]n (1) and [(CuCl4)∙(C6H5CH2NH2CH2)2] (2) (L = N,N’-dibenzylethylenediamine) were synthesized by the ethanol refluxing method. Powder X-ray diffraction (PXRD), infrared spectra (IR), elemental analyses, and single crystal X-ray diffraction were used to characterize and verify their structures. Structural analyses showed that the asymmetric unit of compound (1), composed of two Cu(II) cations, three acetate anions, and half of the ligand, was bridged by one acetate to obtain an infinite 1D cha

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Sadiq, Zainab Majid, and Ahlam Marouf Al-Azzawi. "Design, synthesis and antimicrobial activity screening of new dimethyl maleimidyl heterocyclic derivatives based on 4-(N-dimethyl maleimidyl) phenyl hydrazide." Edelweiss Applied Science and Technology 9, no. 5 (2025): 120–35. https://doi.org/10.55214/25768484.v9i5.6806.

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The research involved the design and synthesis of a collection of innovative dimethyl maleimide heterocyclic derivatives through a multistep synthesis process. The synthesis of compound [1] ethyl-4-(N-dimethyl maleimidyl) benzoate was achieved through the reaction of dimethyl maleic anhydride with ethyl-4-amino benzoate. In the second stage, molecule [1] was reacted with hydrazine hydrate to provide compound [2] 4-(N-dimethyl maleimidyl)phenyl hydrazide. Compound [2] is the crucial precursor from which all objectives compounds were produced. In the third step, compound [2] was subjected to a c

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Muharni, Muharni, Fitrya Fitrya, Milanti Okta Ruliza, Dwi Anjar Susanti, and Elfita Elfita. "Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi Penicillium sp the Leave of Kunyit Putih (Curcuma zedoaria)." Indonesian Journal of Chemistry 14, no. 3 (2014): 290–96. http://dx.doi.org/10.22146/ijc.21241.

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Two compounds from cultivation of the endophytic fungi Penicillium sp of leaves of kunyit putih (Curcuma zedoaria have been isolated. The endophytic fungus was cultivated on 5 L of Potatos Dextrose Broth (PDB) medium at room temperature (no shaking) for 3 weeks. The cultures were extracted with ethyl acetate to afford 3.0 g of residue after removal of the solvent under reduced pressure. The extract was separated and purified by silica gel column chromatography (CC) and afforded two pure compounds as colorless oily liquid (compound 1) and yellow crystal (compound 2). The structure of these comp

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Al-darraji, Asmaa Safwan, and Mohamed H.Mohamed. "The Synthesis and Preliminary Anticancer Evaluation of 6-Mercaptopurine -Methotrexate Conjugate as Possible Mutual Prodrug." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 28, no. 1 (2019): 114–24. http://dx.doi.org/10.31351/vol28iss1pp114-124.

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Small molecules drug conjugate mutual prodrug design (SMDC) composed of folate &lethal agent conjugate , rigidly bonded via hydrophilic bridge& self immolative disulfide bond ; represent new interesting approaches for cancer treatment , the component of SMDC intended to be as possible suit targeted folate receptor , along with greater conservation of component until reaching targeting tumor tissue . The designing & synthesis of compound VI & IIX derived from 6-MP & MTX conjugate altogether as mutual prodrug were processed forward successfully by multiple steps procedure , a

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Rudawska, Anna. "The Impact of the Acidic Environment on the Mechanical Properties of Epoxy Compounds in Different Conditions." Polymers 12, no. 12 (2020): 2957. http://dx.doi.org/10.3390/polym12122957.

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The aim of this work was to determine the impact of the acidic environment on the mechanical properties of two epoxy compounds in different conditions. The samples were made from the epoxy compounds composed of the epoxy resin (based on Bisphenol A), triethylenetetramine curing agent (unmodified compound), and calcium carbonate (CaCO3) (modified compound). The epoxy compound samples were seasoned for the following period of time (i.e., one week, one month, and three months). The environment was tap water and the acidic environment had three different concentrations of acetic acid (3%, 6%, and

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Dofuor, Aboagye Kwarteng, Temitayo Samson Ademolue, Cynthia Mmalebna Amisigo, Kwaku Kyeremeh, and Theresa Manful Gwira. "Chemical Derivatization and Characterization of Novel Antitrypanosomals for African Trypanosomiasis." Molecules 26, no. 15 (2021): 4488. http://dx.doi.org/10.3390/molecules26154488.

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The search for novel antitrypanosomals and the investigation into their mode of action remain crucial due to the toxicity and resistance of commercially available antitrypanosomal drugs. In this study, two novel antitrypanosomals, tortodofuordioxamide (compound 2) and tortodofuorpyramide (compound 3), were chemically derived from the natural N-alkylamide tortozanthoxylamide (compound 1) through structural modification. The chemical structures of these compounds were confirmed through spectrometric and spectroscopic analysis, and their in vitro efficacy and possible mechanisms of action were, s

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Corrêa, Rodrigo S., Lucienir P. Duarte, Grácia D. F. Silva, Djalma M. de Oliveira, Javier Ellena та Antônio C. Doriguetto. "16α-Hydroxyfriedelin and 3-Oxo-16-methylfriedel-16-ene as Building Blocks: Crystal Structure and Hirshfeld Surfaces Decoding Intermolecular Contacts". Journal of Crystallography 2013 (24 жовтня 2013): 1–6. http://dx.doi.org/10.1155/2013/539163.

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In this paper the importance of C–H⋯O intermolecular hydrogen bonds and van der Waals forces in crystal packing stabilization of 16α-hydroxyfriedelin (1) and 3-oxo-16-methylfriedel-16-ene (2) is described. Compound 1 is a natural product isolated from the hexane extract of Salacia elliptica branches, whereas compound 2 is obtained from compound 1 after dehydration accompanied by methyl migration of C-17 to C-16. The single-crystal X-ray diffraction experiments for 1 and 2 were carried out at 150 K, and the crystallographic study demonstrated that these compounds crystallize in noncentrosymmetr

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Viriyaadhammaa, Natsima, Aroonchai Saiai, Waranya Neimkhum, et al. "Cytotoxic and Antiproliferative Effects of Diarylheptanoids Isolated from Curcuma comosa Rhizomes on Leukaemic Cells." Molecules 25, no. 22 (2020): 5476. http://dx.doi.org/10.3390/molecules25225476.

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Curcuma comosa belongs to the Zingiberaceae family. In this study, two natural compounds were isolated from C. comosa, and their structures were determined using nuclear magnetic resonance. The isolated compounds were identified as 7-(3,4-dihydroxyphenyl)-5-hydroxy-1-phenyl-(1E)-1-heptene (1) and trans-1,7-diphenyl-5-hydroxy-1-heptene (2). Compound 1 showed the strongest cytotoxicity effect against HL-60 cells, while its antioxidant and anti-inflammatory properties were stronger than those of compound 2. Compound 1 proved to be a potent antioxidant, compared to ascorbic acid. Neither compounds

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Appenzeller, Tim. "Compound Compound Eye." Scientific American 258, no. 6 (1988): 30. http://dx.doi.org/10.1038/scientificamerican0688-30a.

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Lubamba, Bob, Timothy Jensen, and Randall McClelland. "Rapid Detection of Direct Compound Toxicity and Trailing Detection of Indirect Cell Metabolite Toxicity in a 96-Well Fluidic Culture Device for Cell-Based Screening Environments: Tactics in Six Sigma Quality Control Charts." Applied Sciences 12, no. 6 (2022): 2786. http://dx.doi.org/10.3390/app12062786.

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Microfluidic screening tools, in vitro, evolve amid varied scientific disciplines. One emergent technique, simultaneously assessing cell toxicity from a primary compound and ensuing cell-generated metabolites (dual-toxicity screening), entails in-line systems having sequentially aligned culture chambers. To explore dual-tox screens, we probe the dissemination of nutrients involving 1-way transport with upstream compound dosing, midstream cascading flows, and downstream cessation. Distribution of flow gives rise to broad concentration ranges of dosing compound (0→ICcompound100) and wide-ranging

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Arai, Naoki, Shunsuke Yoshikawa, Nobuaki Yasuo, Ryunosuke Yoshino, and Masakazu Sekijima. "Compound property enhancement by virtual compound synthesis." Journal of Bioinformatics and Computational Biology 16, no. 03 (2018): 1840016. http://dx.doi.org/10.1142/s0219720018400164.

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During drug discovery, drug candidates are narrowed down over several steps to develop pharmaceutical products. The theoretical chemical space in such steps is estimated to be [Formula: see text]. To cover that space, extensive virtual compound libraries have been developed; however, the compilation of extensive libraries comes at large computational cost. Thus, to reduce the computational cost, researchers have constructed custom-made virtual compound libraries that focus on target diseases. In this study, we develop a system that generates virtual compound libraries from input compounds. Whe

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AL-ALAAF, Hiba Ameen, and Mohammed A. AL-IRAQI. "Synthesis of Some New Hydrazones from Quinazolinone Moiety." Eurasia Proceedings of Science Technology Engineering and Mathematics 16 (December 31, 2021): 52–56. http://dx.doi.org/10.55549/epstem.1068546.

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Methyl α-[(4-oxoquinazolin-2-yl)thio]acetate (4) is one of the important heterocyclic compounds. It isused as a precursor to synthesis new derivatives of quinazolin-4-one moiety. The compound (4) was synthesized via a series of steps from anthranilic acid. The anthranilic acid was converted to its methyl ester (1) by esterification with methanol under acidic condition. The ester (1) was reacted with chloroacetyl chloride to produce methyl α-chloroacetamido benzoate (2). The chloro compound (2) was converted to the corresponding thiocyanato compound (3) by its reaction with ammonium thiocyanate

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Hosny, Mona A., Wafaa A. Mokbe, and Emtithal A. El-Sawi. "Synthesis and Evaluation of Important Biologically Active Heterocyclic Compounds: Schiff Bases, Oxadiazole and Pyrazolyl Derivatives." JOURNAL OF ADVANCES IN CHEMISTRY 9, no. 2 (2013): 1892–99. http://dx.doi.org/10.24297/jac.v9i2.2341.

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In this work, we prepared an excellent yield of (2-oxo-2H-pyrano[3,2-h] quinolin-4-yl) acetic acid; compound (1) and from the reaction of it with hydrazine hydrate (100%) we obtain 2-(2-oxo-2H-pyrano [3,2-h] quinolin-4-yl) aceto hydrazide (2) which is the starting material for the synthesis of several series of new compounds: such as schiff’s bases (3a-e) and compound (4) in good yields, hydrazide derivatives like compound (5), derivatives of mercapto oxadiazole as compound (6) and derivatives of pyrazolyl as compound (7). All these compounds were found to possess high antimicrobial activity a

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Journal, Baghdad Science. "Synthesis, Characterization and Biological Activates Studies of some New Derivatives From 2-aminoo-5-mercapto-1, 3, 4-thiadiazole." Baghdad Science Journal 15, no. 1 (2018): 48–56. http://dx.doi.org/10.21123/bsj.15.1.48-56.

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In this work, thiadiazole derivatives were prepared by taking advantage of active sites in (2-amino-5-mercapto-1, 3, 4-thiadiazole) as a starting material base. The main heterocyclic compounds (1, 3, 4-thiadiazole, oxazole) etc, 2-amino-5-mercapto-1,3,4-thiadiazole compound (1) was prepared by cyclic closure of thiosemicarbazide compound with anhydrous sodium carbonate and carbon disulfide. Oxidation of (1) via hydrogen peroxide, to have (2) which was treated with chloro acetyl chloride to get (3). Preparation of thiazole ring (4) was from reacting of (3) with thiourea. Synthesis of diazonium

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Dhey, Anselmania Kartini, Eka Rasuna Andriani, Berliana Mardawati, et al. "Isolation and activity test of antioxidant, antibacterial, and cytotoxic compounds from the stem bark of Aglaia foveolata Pannell." Pharmacia 70, no. 4 (2023): 1329–34. http://dx.doi.org/10.3897/pharmacia.70.e111111.

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Aglaia foveolata Pannell (A. foveolata) is a type of plant that has many benefits, including the skin, leaves, roots, and seeds as medicinal ingredients. The potential of this plant is inseparable from the content of various bioactive compounds. This study aims to isolate, characterize the active compound from the stem bark of A. foveolata and test its activity as an antioxidant with the ABTS method, cytotoxic (MCF-7 cancer cells) with the MTT method, and antibacterial (bacterial strains ATCC and MDR) with the MIC. There are four isolated compounds obtained, namely (1) 17,24-epoxy-25-hydroxyba

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Kucherenko, L. I., Yu V. Karpenko, M. V. Ohloblina, et al. "Monitoring the properties of 1,2,4-triazole derivatives for the development of original antimicrobial drugs." Zaporozhye Medical Journal 26, no. 6 (2024): 481–89. https://doi.org/10.14739/2310-1210.2024.6.309034.

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Aim. A comprehensive study on the antimicrobial properties of new 1,2,4-triazole derivatives using the tools of in silico and in vitro studies. Materials and methods. Computer search techniques were used to find a compound with a strong antibacterial activity; in silico molecular docking (receptors for class A (PDB id: 1n9b) and class A SHV-1 (PDB id: 2zd8) beta-lactamase) and in vitro studies on 16 types of microorganisms. Then, the in silico analyzed compounds were tested in vitro for antimicrobial activity. After preparing solutions of different concentrations, the culture growth was measur

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Saito, Tetsuji, and Hayai Watanabe. "Magnetic and Thermoelectric Properties of Fe2CoGa Heusler Compounds." Inorganics 13, no. 2 (2025): 33. https://doi.org/10.3390/inorganics13020033.

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The investigation of the properties of Heusler compounds is an important task that will pave the way for new applications in various fields related to magnetics and thermoelectrics. This study examines the magnetic and thermoelectric properties of Fe2CoGa Heusler compounds prepared by casting and subsequent annealing. The Fe2CoGa Heusler compound was found to be ferromagnetic, with a large saturation magnetization of 110 emu/g and a high Curie temperature of 1011 K. The Fe2CoGa Heusler compound was a good thermoelectric material, with a negative Seebeck coefficient of −44 μV/K, a low electrica

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Journal, Baghdad Science. "Synthesis, Characterization of Poly Heterocyclic Compounds, and Effect on Cancer Cell (Hep-2) In vitro." Baghdad Science Journal 15, no. 4 (2018): 415–524. http://dx.doi.org/10.21123/bsj.15.4.415-524.

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A synthesis series of new heterocyclic derivatives (A2-A7) (pyrrole, pyridazine, oxazine and imidazol) derived from 4-acetyl-2,5-dichloro-1-(3,5-dinitrophenyl)-1H-pyrrole-3-carboxylate(A1) have been synthesised. Synthesis of compound (A2) by the reaction of starting material (A1) with hydroxyl amine hydrochloride in the presence of pyridine. Compound (A2) was reacted with hydrazine hydrate in dry benzene to give (A3) derivative. The compound )A3( deals with sodium nitrite to give diazonium salt, and the reaction diazonium salt with ethyl acetoacetate to produce compound (A4). To a mixture of c

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Rybarski, Mateusz. "O różnicy między wielordzennymi złożeniami dwuczłonowymi i wieloczłonowymi." LingVaria 20, no. 1(39) (2025): 41–48. https://doi.org/10.12797/lv.20.2025.39.03.

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ABOUT THE DIFFERENCE BETWEEN TWO-MEMBER AND MULTI-MEMBER COMPOUNDS The aim of this article is to present terminological opposition two-member compound – multi-member compound. In its first part, the author defines the term two-member compound and describes examples of this category. In the second one he explains the term multi-member compound and discusses its examples, arguing why they cannot be interpreted as two-member compounds. Finally, the author claims that there is no simple way to distinguish between two-member and multi-member compounds.

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Sisvinda, Felix Stefani. "English Compound Words Used in The Jakarta Post’s Health Column on Third Week of June 2020." Indonesian Journal of English Language Studies (IJELS) 8, no. 1 (2022): 1–16. http://dx.doi.org/10.24071/ijels.v8i1.3231.

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This study aims to describe the orthographic features, word formation and the meaning of compound words related to COVID-19 pandemics used in The Jakarta Post’s Health Column Article on Third Week of June 2020. There are three research questions in this study: (1) What are orthographic features found in the compound words, (2) What are the type of compound words and their lexical categories, and (3) How do the compound words create meaning. To answer the research question, the writer use the theory of morphology and semantics. The findings showed there are 34 compound words in The Jakarta Post

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Matson, Sandra L., Moneesh Chatterjee, David A. Stock, et al. "Best Practices in Compound Management for Preserving Compound Integrity and Accurately Providing Samples for Assays." Journal of Biomolecular Screening 14, no. 5 (2009): 476–84. http://dx.doi.org/10.1177/1087057109336593.

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Preserving the integrity of the compound collection and providing high-quality materials for drug discovery in an efficient and cost-effective manner are 2 major challenges faced by compound management (CM) at Bristol-Myers Squibb (BMS). The demands on CM include delivering hundreds of thousands of compounds a year to a variety of operations. These operations range from single-compound requests to hit identification support and just-in-time assay plate provision for lead optimization. Support needs for these processes consist of the ability to rapidly provide compounds as solids or solutions i

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