Relevant bibliographies by topics / The developed method is stability indicating

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'The developed method is stability indicating'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "The developed method is stability indicating"

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Upadhyay, Priya Shitalaprasad* Dr Vinay C. Darji Bhumi Patel Jaymin Patel. "DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ASSAY METHOD FOR ESTIMATION OF TERIFLUNOMIDE IN TABLET DOSAGE FORM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 04 (2018): 3209–19. https://doi.org/10.5281/zenodo.1240480.

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A simple, rapid, economical, precise and accurate Stability indicating RP-HPLC method for Teriflunomide In its Pharmaceutical Dosage Form has been developed. A reverse phase high performance liquid chromatographic method was developed for the Teriflunomide in its Pharmaceutical Dosage Form has been developed. The separation was achieved by Cosmosil (250mm x 4.6 mm) column and Buffer (pH 4.0): Methanol (40:60) as mobile phase, at a flow rate of 1 ml/min. Detection was carried out at 248 nm. Retention time of Teriflunomide was found to be 3.300 min. The method has been validated for linearity, a
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Alam, Prawez, Faiyaz Shakeel, Mohammed H. Alqarni, et al. "Determination of Cordycepin Using a Stability-Indicating Greener HPTLC Method." Separations 10, no. 1 (2023): 38. http://dx.doi.org/10.3390/separations10010038.

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A wide range of analytical techniques have been reported to determine cordycepin (CDN) in various sample matrices. Nevertheless, greener analytical approaches for CDN estimation are scarce in the literature. As a result, this study was designed to develop and validate a stability-indicating greener “high-performance thin-layer chromatography (HPTLC)” technique for CDN determination in a laboratory-developed formulation. The greener eluent system for CDN detection was ethanol–water (75:25 v/v). At a wavelength of 262 nm, CDN was measured. The greenness scale of the proposed analytical technolog
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Satheesha, Babu Birur Kotappa, Rohith Ganapathi Bhatta, and Sadashivaiah Rudragangaiah. "New Stability Indicating LC Method for Novel Antidiabetic Drug Canagliflozin Hemihydrate Quantification; Development and Validation." Pharmaceutical Methods 10, no. 2 (2019): 6. https://doi.org/10.5281/zenodo.14586135.

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Introduction: The present research includes a new RP-HPLC method development and validation of Canagliflozin Hemihydrate (CANAG) a novel antidiabetic drug. The novel analytical method developed was employed for the quantification of CANAG in bulk drug and as an Active Pharmaceutical Ingredient (API) in tablet formulation. Methods: The present study utilized HPLC instrument (Shimadzu) comprises of ultraviolet detector and COSMICSIL 100 C18 (250 × 4.6 mm) 5 µm column. The mobile phase consists of acetonitrile: water (70:30%v/v) of pH 3.0±0.05 adjusted by addition of ortho-phos
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Sangeetha, M., Tirumala ., and Nagamallika . "STABILITY INDICATING RP-LC ASSAY METHOD FOR CARISOPRODOL." International Journal of Current Pharmaceutical Research 9, no. 6 (2017): 79. http://dx.doi.org/10.22159/ijcpr.2017v9i6.23434.

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Objective: A reverse phase stability-indicating HPLC method was developed for the determination of Carisoprodol in pharmaceutical dosage forms. The chromatographic elution was achieved on C18, 250 mm × 4.6 mm, 5-μm particle size column.Methods: The mobile phase contains a mixture of water and acetonitrile in ratio of 60:40 v/v. The flow rate was 1.0 ml min-1 and was detected by Refractive index detector.Results: The method was proven to be linear over a range of 1 to 4 mg/ml with a mean correlation coefficient of 0.99998. The %mean recovery is in the range of 100.55% to 101.11% and %RSD was le
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Sonal, Vaishnav H. Dr Vinay C.Darji Jaymin G.Patel Bhumi patel. "STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF TIAGABINE HYDROCHLORIDE IN TABLET." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 04 (2018): 2836–28641. https://doi.org/10.5281/zenodo.1226742.

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A simple, rapid, economical, precise and accurate Stability indicating RP-HPLC method for estimation of Tiagabine Hydrochloride in their dosage form has been developed. A reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of Tiagabine Hydrochloride. in their dosage form has been developed. The separation was achieved by column C18 (250mm x 4.6 mm) Hypersil BDS and Buffer (pH 4.5): Methanol (85:15 % v/v) as mobile phase, at a flow rate of 1 ml/min. Detection was carried out at 260 nm. Retention times of Tiagabine Hydrochloride were found t
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Ghante, Minal, Pooja Siddheshware, Vidhya Bhusari, Sanjay Sawant, Vasundhara Sawant, and Preeti Kulkarni. "STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF ELIGLUSTAT TARTRATE." Indian Drugs 59, no. 04 (2022): 57–59. http://dx.doi.org/10.53879/id.59.04.12344.

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For determination of eliglustat tartrate, a new, specific, simple, accurate (recovery) and precise stability indicating HPLC method has been developed and validated according to ICH Q2(R1) guidelines. The HPLC method was developed using acetonitrile: 0.1 % orthophosphoric acid 40:60 (V/V) as mobile phase, with pH of mobile phase adjusted to 3.0. The column used was HiQSil C-18 (250 mm x 4.6 mm, 5 μm) as stationary phase at a flow rate of 0.7 mL min-1. Retention time for eliglustat tartarate was found to be 5.9 min. The eluted compounds were detected using a PDA detector. The drug was subjected
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Mrinalini, C. Damle* and Shital P. Ghode. "STABILITY INDICATING CHROMATOGRAPHIC METHOD FOR ESTIMATION OF BEPOTASTINE BESILATE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 06 (2018): 5222–28. https://doi.org/10.5281/zenodo.1289735.

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A Simple, rapid, stability indicating HPTLC method has been developed for estimation of bepotastine besilate. HPTLC separation was carried out on Merck TLC aluminium sheets precoated with silica gel 60F254 using mobile phase as chloroform : methanol. Bepotastine besilate gave sharp peak at RF 0.53 ±0.03 at 225nm.calibration curve was linear in range 5-25ug/band for bepotastine besilate. Stress degradation study was carried out according to ICH guidelines Q1A (R2) and the method was validated as per ICH guideline.
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Mehta, Tushar N., Gunta Subbaiah, and Kilambi Pundarikakshudu. "Determination of Cefdinir by a Stability-Indicating Liquid Chromatographic Method." Journal of AOAC INTERNATIONAL 88, no. 6 (2005): 1661–65. http://dx.doi.org/10.1093/jaoac/88.6.1661.

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Abstract A simple, fast, specific, stability-indicating, and precise reversed-phase liquid chromatographic method was developed for the determination of Cefdinir in its different dosage forms, i.e., capsules and suspensions. The method was developed and optimized by analyzing the placebo preparation, formulations, and degraded samples of the drug substance according to the International Conference on Harmonization. The proposed method can successfully separate the drug from degradation products formed under stress conditions along with pharmaceutical ingredients such as preservatives. The deve
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Amareshwar, Shabada Nikhat Fatima Humera Badar Syeda Saba Sultana. "DETERMINATION OF PAZOPANIB HYDROCHLORIDE IN SOLID DOSAGE FORM BY RP-HPLC METHOD: DEVELOPMENT AND VALIDATION." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 4094–99. https://doi.org/10.5281/zenodo.1048471.

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A simple, accurate, precise, sensitive and stability indicating RP-HPLC method has been developed for the determination of Pazopanib hydrochloride in bulk drug and pharmaceutical dosage form, in which separations are done using develosil C18, 5μm, 150 × 4.6mm i.d. column at a flow rate of 1.0mL/min with an injection volume of 20μL. The beer’s law was obeyed over the concentration range of 5 - 35μg/mL. The correlation coefficient was found to be 0.996 and it showed good linearity, reproducibility, precision in this concentration range. The aim of this paper was to develop and validate the stabi
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Purvasha, S. Khot* Jaymin Ghanshyambhai Patel Bhumi Rajdevbhai Patel. "ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR ESTIMATION OF LERCANIDIPINE HYDROCHLORIDE AND ENALAPRIL MALEATE IN COMBINATION." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 04 (2018): 3144–51. https://doi.org/10.5281/zenodo.1237984.

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Stability indicating RP-HPLC method for simultaneous estimation of Lercanidipine Hydrochloride and Enalapril Maleate in their Combined Dosage Form has been developed. A reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of Lercanidipine HCl and Enalapril Maleate in their combined dosage form. The separation was achieved by column C18 (250mm x 4.6 mm) Hypersil BDS and Buffer (pH 5.0): Methanol (30:70 % v/v) as mobile phase, at a flow rate of 1 ml/min. Detection was carried out at 233 nm. Retention time of Lercanidipine HCl and Enalapril Ma
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Dissertations / Theses on the topic "The developed method is stability indicating"

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Van, den Berg Elaine. "Development of a stability indicating HPLC method for the Pheroid™ delivery system / Elaine van den Berg." Thesis, North-West University, 2010. http://hdl.handle.net/10394/5105.

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Stability plays an important role in the development of a new drug product. High Performance Liquid Chromatography (HPLC) is considered a stability indicating method of analysis. It is widely used in the pharmaceutical industry for the quantification of small organic molecules during stability testing. Previous stability studies conducted on Pheroid™-based drug products, experienced problems with the generation of reliable data by means of HPLC analysis. With these studies it was concluded that the inconclusive results could either be attributed to the stability of the delivery system itself a
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Bae, Stacy S. "A HPLC/ESI-MS method developed and validated to evaluate the quantity, identity, and stability of the alkylamides in ethanolic extracts of Spilanthes acmella." Greensboro, N.C. : University of North Carolina at Greensboro, 2007. http://libres.uncg.edu/edocs/etd/1411/umi-uncg-1411.pdf.

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Thesis (M.S.)--University of North Carolina at Greensboro, 2007.<br>Title from PDF t.p. (viewed Oct. 18, 2007). Directed by Nadja B. Cech; submitted to the Dept. of Chemistry and Biochemistry. Includes bibliographical references (p. 68-71).
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SANTOS, Bruno Aires dos. "Desenvolvimento e Validação de Método Indicativo de Estabilidades Para Comprimidos Revestidos de Metildopa." Universidade Federal de Pernambuco, 2014. https://repositorio.ufpe.br/handle/123456789/17159.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-06-28T14:51:48Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) UNIVERSIDADE FEDERAL DE PERNAMBUCO (Salvo Automaticamente)_correto.pdf: 1889034 bytes, checksum: eb0752322509ac8a41b42b336e30870a (MD5)<br>Made available in DSpace on 2016-06-28T14:51:48Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) UNIVERSIDADE FEDERAL DE PERNAMBUCO (Salvo Automaticamente)_correto.pdf: 1889034 bytes, checksum: eb0752322509ac8a41b42b336
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Souza, Aline de. "Desenvolvimento de metodologias indicativas de estabilidade para medicamentos utilizados como diuréticos." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-15122015-084128/.

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Os diuréticos aumentam o fluxo urinário e a excreção de sódio e são utilizados para ajustar o volume e/ou a composição dos líquidos corporais em uma variedade de situações clínicas. A furosemida é um agente diurético potente que induz uma poderosa diurese. É utilizada no tratamento de edema associado com o coração e doenças renais. Nesta pesquisa objetivou-se desenvolver métodos indicativos de estabilidade para a furosemida, por eletroforese capilar em solução livre (FSCE) e cromatografia liquida de alta eficiência (CLAE). O método por FSCE utilizou um capilar de sílica fundida com comprimento
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Galdos, Angel Arturo Gaona. "Desenvolvimento de metodologias indicativas de estabilidade para medicamentos que atuam no diabetes mellitus tipo II." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-04042013-092152/.

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O diabetes mellitus (DM) é uma síndrome na qual o metabolismo de hidratos de carbono, gorduras e proteínas está alterado, por falta de secreção de insulina ou por diminuição da sensibilidade tissular a este hormônio. O DM pode ser do tipo I, também denominado diabetes mellitus insulinodependente (DMID), caracterizado pela falta de secreção da insulina, e do tipo II, também denominado diabetes mellitus não insulinodependente (DMNID), caracterizado pela menor sensibilidade dos tecidos efetores às ações metabólicas da insulina. Embora ainda não haja cura definitiva, há vários tratamentos disponív
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Maranho, Rafael Finocchiaro. "Desenvolvimento de um método indicativo de estabilidade para ondansetrona." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/46/46137/tde-14122017-144542/.

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ultravioleta e espectrometria de massas para análise do teor e limite de impurezas e compostos de degradação para o principio ativo farmacêutico ondansetrona e três diferentes formas farmacêuticas foi desenvolvido utilizando conceitos de qualidade analítica por planejamento (aQbD) e validado de acordo com os requerimentos da USP-NF e do ICH. O método desenvolvido apresentou capacidade de separação de vinte compostos detectados nas amostras envolvidas no estudo: o princípio ativo ondansetrona, sete impurezas descritas nos principais compêndios farmacopéicos mundiais (United States Pharmacopeia-
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Stubbs, C., J. M. Haigh, and I. Kanfer. "A stability-indicating liquid chromatographic method for the analysis of erythromycin in stored biological fluids using amperometric detection." 1987. http://hdl.handle.net/10962/d1006592.

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A simple, sensitive and reliable high-performance liquid chromatographic procedure has been developed for the determination of erythromycin in human serum and urine using amperometric detection. A solid-phase extraction procedure was used followed by chromatography on a reverse-phase column. The mean recovery of erythromycin from serum and urine was 80%. This method allows both erythromycin and its principle degradation product, anhydroeythromycin, to be determined during a period of sample storage at 4 degree C and minus 15 degree C. The method is sufficiently sensitive and precise and is thu
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Chaibva, F. A., and Roderick Walker. "Development and validation of a stability-indicating analytical method for the quantitation of oxytocin in pharmaceutical dosage forms." 2006. http://hdl.handle.net/10962/d1006030.

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A single stability-indicating assay for oxytocin (OT) in pharmaceutical dosage forms using gradient elution over 21 min has been reported in the literature. Furthermore, published and compendial methods for the analysis of OT containing dosage forms also involve using HPLC with gradient elution and complicated mobile phases that include hydrophobic ion pairing agents. A simple isocratic and stability-indicating assay was developed and validated. The conditions are as follows, column: Phenomenex® C18 Hypersil, 5 μm packing, 4.6 mm × 150 mm with acetonitrile–phosphate buffer (pH 5; 0.08 M) (20:8
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Lin, Chia-yu, and 林佳諭. "Development of Rosuvastatin calcium oral tablet bioequivalent with Crestatinâ -Investigate the degradation of this product by a Stability- Indicating LC Method." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/38793410768564788803.

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碩士<br>大仁科技大學<br>製藥科技研究所<br>100<br>Rosuvastatin calcium, bis [(E)-7 [4-(4-fluorophenyl)-6 isopropyl- 2-[methyl (methyl-sulphonyl) amino] pyrimidin-5-yl] (3R, 5S) -3,5-dihydroxyhept-6-enoic acid] calcium salt, was approved by the US FDA in August 2003 to reduce cholesterol levels in patients with hypercholesterolaemia. This agent is a selective, potent and competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase catalizing the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in cholesterol biosynthesis. In the literature, the Rosuvastatin ca
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Llobet, Maria Teresa Pardal Porto. "Forced degradation study of fencarol 10 mg/ml solution for injection using UPLC method." Master's thesis, 2014. http://hdl.handle.net/10451/38739.

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Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2014<br>Force degradation study is an important tool in pharmaceutical process in order to develop stability-­‐indicating methods that lead to quality data and to understand degradation pathways of drug substances and drug product. In this study, Fencarol 10mg/mL solution for injection was submitted to different conditions to determine the effect of excipients present in the formulation in assessing drug product stability and to develop and demonstrate the specificity of stability-indi
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Books on the topic "The developed method is stability indicating"

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Voronin, Evgeniy, Aleksandr Chibunichev, and Yuriy Blohinov. Reliability of solving inverse problems of analytical photogrammetry. INFRA-M Academic Publishing LLC., 2023. http://dx.doi.org/10.12737/2010462.

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The monograph is devoted to computational aspects of photogrammetric reconstruction of narrow-angle bundles of projecting beams that existed during the survey. Methods of improving the conditionality of systems of linear equations, ensuring the convergence of iterative refinement of their roots, increasing the stability of calculations in finite precision machine arithmetic are considered. The main efforts are focused on solving the problem of establishing reliable measurement weights within the framework of the least squares method. The criteria for the reliability of the weights are determin
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Kesoretskikh, Ivan, and Sergey Zotov. Landscape vulnerability: concept and assessment. INFRA-M Academic Publishing LLC., 2019. http://dx.doi.org/10.12737/1045820.

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The monograph presents a methodology for assessing the vulnerability of landscapes to external influences. A comparative analysis of the concepts of "stability", "sensitivity", "vulnerability" in relation to natural complexes. An overview of existing methods for assessing the vulnerability of natural complexes is presented. The author's method of assessing the vulnerability of landscapes to anthropogenic impacts is described. The methodology is based on: selection and justification of criteria for assessing the vulnerability of landscapes; preparation of a parametric matrix and gradation of as
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Rp-Hplc Stability Indicating Assay and Simultaneous Estimation Method for the Combination of Glecapravir and Pibrentasvir in Tablet Dosage Form. Independently Published, 2020.

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Boudreau, Joseph F., and Eric S. Swanson. Continuum dynamics. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198708636.003.0019.

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The theory and application of a variety of methods to solve partial differential equations are introduced in this chapter. These methods rely on representing continuous quantities with discrete approximations. The resulting finite difference equations are solved using algorithms that stress different traits, such as stability or accuracy. The Crank-Nicolson method is described and extended to multidimensional partial differential equations via the technique of operator splitting. An application to the time-dependent Schrödinger equation, via scattering from a barrier, follows. Methods for solv
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Sobczyk, Eugeniusz Jacek. Uciążliwość eksploatacji złóż węgla kamiennego wynikająca z warunków geologicznych i górniczych. Instytut Gospodarki Surowcami Mineralnymi i Energią PAN, 2022. http://dx.doi.org/10.33223/onermin/0222.

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Hard coal mining is characterised by features that pose numerous challenges to its current operations and cause strategic and operational problems in planning its development. The most important of these include the high capital intensity of mining investment projects and the dynamically changing environment in which the sector operates, while the long-term role of the sector is dependent on factors originating at both national and international level. At the same time, the conditions for coal mining are deteriorating, the resources more readily available in active mines are being exhausted, m
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Book chapters on the topic "The developed method is stability indicating"

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Dhiraj, Kumar, and Himansu Bhusan Samal. "Development of stability indicating RP-HPLC method for simultaneous estimation of sacubitril and valsartan in pure and pharmaceutical dosage form." In Advancement in Animal Handling and Generative AI for Pre-clinical Studies. CRC Press, 2025. https://doi.org/10.1201/9781003672869-20.

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Cheong, Chikako, and Tsutomu Miura. "Certification of Reference Materials of Nutrients in Seawater, NMIJ CRM 7601-a, 7602-a, and 7603-a." In Springer Oceanography. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-2520-8_5.

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Abstract The National Metrology Institute of Japan (NMIJ) has developed three levels of certified reference materials (CRMs) (NMIJ CRM 7601-a, 7602-a, and 7603-a) for nutrient analysis to provide SI traceability of analysis values of nutrients (nitrate, nitrite, phosphate, and dissolved silica) in oceanographic observations and to enable the comparison of these values across time and space. These property values were determined using the analytical results of multiple analytical methods and standard solutions of inorganic ions and elements as the SI traceability source. Depending on their char
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Han, Wenbin, Zechuan Guan, Shanfang Huang, and Jian Deng. "Multi-physics Coupling Analyses of Nuclear Thermal Propulsion Reactor." In Springer Proceedings in Physics. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-1023-6_80.

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AbstractNuclear thermal propulsion (NTP) reactors have high-temperature solid-state characteristics and significant thermal expansion, which therefore require multi-physics coupling analyses. In this paper, the framework of Neutronics, Thermal-Hydraulics and Mechanics coupling (N/T-H/M) of nuclear thermal propulsion reactor is developed, and the typical reactor XE-2 is analyzed with this method. The results show that the N/T-H/M coupling will bring -1049 pcm negative reactivity, of which the thermal expansion effect accounts for 22%, indicating that the nuclear thermal propulsion reactor has a
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Liu, Junliang, Guangxiu Fang, Jiaxing Lu, and Han Jin. "Study on the New Preparation Method and Properties of Green Self-Compacting Transparent Concrete." In Lecture Notes in Civil Engineering. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-4090-1_11.

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AbstractThrough reading and integrating a large amount of literature, this paper innovatively proposed a new method of making transparent concrete. On this basis, we added fly ash and slag powder to replace cement according to different volume ratios, and developed four new types of green self-compacting transparent concrete with different mix ratios. By testing the compressive strength, tensile strength, elastic modulus and thermal conductivity of these concrete, found that according to (20%, 20%) added fly ash and slag powder cement instead of new green self-dense light transparent concrete
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Mitsuda, Hitoshi, Takeshi Fujii, Chisato Nagaya, and Naoyuki Tahara. "Production History of Certified Reference Materials of Nutrients in Seawater Developed by KANSO TECHNOS CO., LTD." In Springer Oceanography. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-2520-8_2.

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Abstract The development of reference materials for nutrients in seawater (RMNS) started in 1993, and production and distribution of RMNS began in 2000. In 2011, KANSO TECHNOS CO., LTD. (KANSO) became accredited as a reference material producer (International Organization for Standardization, ISO 17034). Since then, RMNS has been distributed worldwide as an SI-traceable certified reference material. RMNS (1) is 100% natural seawater (no additives); (2) contains all nutrients in one bottle; (3) is used directly without any dilution step; (4) is available as several lots of low to high nutrient
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Wang, Zhijun, Riyu Cong, Ruihong Wang, and Zhihui Wang. "Digital Twin for Power Load Forecasting." In Lecture Notes in Electrical Engineering. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-2409-6_36.

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Abstract In this work, a novel Digital Twin model using attention mechanism integrated with LSTM to forecast the future power load of a specific user is developed. The power load prediction research is done in detail by taking into account important factors such as temperature, humidity, and the price of electricity. Therefore, LSTM networks are adopted for deep learning of the historical power load data, while the attention mechanism is used to assign weights to the significance of various factors that affect the power load and make better predictions of the future power load. The results of
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Zhu, Yanbei. "Certified Reference Material of Trace Elements in Seawater, NMIJ CRM 7204-a." In Springer Oceanography. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-2520-8_16.

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Abstract A certified reference material (CRM) for the determination of trace elements in seawater samples was developed by the National Metrology Institute of Japan (NMIJ) and coded as NMIJ CRM 7204-a, in which the concentrations of trace elements were elevated to facilitate the quality control in analysis for environment conservation purpose. It is a complement to CRMs aimed at quality control in natural seawater samples, e.g. NASS and CASS series by National Research Council of Canada, as well as GEOTRACES standards and reference materials. NMIJ CRM 7204-a was characterized for the analysis
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Weyer, Johannes. "Safe Transitions in Complex Systems." In Climate Change and Safety in High-Risk Industries. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-56995-1_5.

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AbstractComplex systems, including energy and transportation systems, constitute a crucial part of modern societies’ critical infrastructure. It is imperative to ensure their stability even during periods of crisis or fundamental transformation, such as sustainability transformation. It is difficult to anticipate how individuals will respond to policy interventions aimed at preserving stability, for example, by banning cars from congested roads, or to policy interventions aimed at fundamentally altering the system, for instance, by promoting renewable energies. A conflict of interest may occur
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Varfolomeev, Sergey, Bella Grigorenko, Sofya Lushchekina, Patrick Masson, Galina Mahaeva, and Alexander Nemuchin. "Human cholinesterases." In ORGANOPHOSPHORUS NEUROTOXINS. Publishing Center RIOR, 2020. http://dx.doi.org/10.29039/21_069-126.

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The work is devoted to modeling the elementary stages of the hydrolysis reaction in the active site of enzymes belonging to the class of cholinesterases — acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The study allowed to describe at the molecular level the effect of the polymorphic modification of BChE, causing serious physiolog ical consequences. Cholinesterase plays a crucial role in the human body. AChE is one of the key enzymes of the central nervous system, and BChE performs protective functions in the body. According to the results of calculations using the combined meth
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Varfolomeev, Sergey, Bella Grigorenko, Sofya Lushchekina, and Alexander Nemuchin. "Human cholinesterases." In Organophosphorous Neurotoxins. Publishing Center RIOR, 2020. http://dx.doi.org/10.29039/chapter_5e4132b5f22366.15634219.

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The work is devoted to modeling the elementary stages of the hydrolysis reaction in the active site of enzymes belonging to the class of cholinesterases — acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The study allowed to describe at the molecular level the effect of the polymorphic modification of BChE, causing serious physiolog ical consequences. Cholinesterase plays a crucial role in the human body. AChE is one of the key enzymes of the central nervous system, and BChE performs protective functions in the body. According to the results of calculations using the combined meth
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Conference papers on the topic "The developed method is stability indicating"

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Imano, Shinya, Jun Sato, Koji Kajikawa, and Tatsuya Takahashi. "Mechanical Properties and Manufacturability of Ni-Fe Base Superalloy (FENIX-700) for A-USC Steam Turbine Rotor Large Forgings." In AM-EPRI 2007, edited by R. Viswanathan, D. Gandy, and K. Coleman. ASM International, 2007. https://doi.org/10.31399/asm.cp.am-epri-2007p0424.

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Abstract To develop 10-ton class forgings with adequate long-term strength and without segregation defects for A-USC steam turbine rotors, researchers modified the chemical composition of Alloy 706 to improve its microstructure stability and segregation properties. The modified Alloy, named FENIX-700, is a γ' phase strengthened alloy without a γ" phase, and its microstructure stability is superior to Alloy 706 at 700°C, as demonstrated by short-term aging tests and phase stability calculations using the CALPHAD method. A trial disk 1-ton class forging of FENIX-700 was manufactured from a doubl
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Feasey, N. D., R. J. Wintle, E. R. Freiter, and M. M. Jordan. "Field Experiences with a Novel near Real Time Monitor for Scale Deposition in Oilfield Systems." In CORROSION 2000. NACE International, 2000. https://doi.org/10.5006/c2000-00117.

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Abstract Mineral scale deposition is a well-known problem for the petroleum industry. The application of scale inhibitors can often prevent such deposits forming, but assessment of the concentrations of these needed for control has relied on indirect methods for assessing brine stability. Such methods use laboratory tests and measurement of scale inhibitor residuals. Recently a new technique for direct measurement of the stability of oilfield brines has been developed. This technique uses TSMR (Thickness Shear Mode Resonator) technology. Deposition on the probe alters resonant frequency, measu
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Bem, Milena Jonas, Samuel Chabot, and Jonas Braasch. "Exploring Spatialization: A Method for Subjective Assessment of Soundscape Preference Using Immersive Environments." In ICAD 2024: The 29th International Conference on Auditory Display. International Community for Auditory Display, 2024. http://dx.doi.org/10.21785/icad2024.026.

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This research explores the application of immersive environments, like the Panorama Screen System, for perception and psychoacoustic experiments. A system is developed to present architectural scenarios visually and sonically by using panoramic images combined with spatialized sound. These audiovisual results are displayed on a human-scale panoramic display, which is integrated with eight loudspeakers for spatial audio rendering. While immersed in this system, participants use a wireless interface as a controller to interact with the experiment and give subjective ratings for their preferences
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Reveles, Nicolas, Adam Weiss, and Parthiv Shah. "An Indirect Stability Method Applied to Whirl Flutter using Computational Fluid Dynamics Actuator Disc Models." In Vertical Flight Society 80th Annual Forum & Technology Display. The Vertical Flight Society, 2024. http://dx.doi.org/10.4050/f-0080-2024-1367.

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A recently developed indirect eigenvalue method is applied to propeller whirl flutter stability using computational fluid dynamics. The use of computationally efficient actuator disc models is compared to actuator blade and wall-resolved models. Actuator disc and blade results are confirmed to be both mesh and time-step independent. Actuator disc models produce stability results that closely emulate analytic quasi-steady approximations, whereas actuator blade models are observed to most closely resemble analytic unsteady approximations. The wall-resolved model of the propeller produces the mos
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Loomis, Jean, Jaye Falls, and Sarah Mouring. "Measured and Predicted Response of a Submerged Towed Sonar Array to Maneuvering Input." In Vertical Flight Society 71st Annual Forum & Technology Display. The Vertical Flight Society, 2015. http://dx.doi.org/10.4050/f-0071-2015-10222.

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There exists a necessity to increase helicopter pilot's safety during mine countermeasure operations. Models have been developed for scenarios involving a cable that is fully submerged in either air or water, but there has been very little testing when the cable is partially submerged. This change in fluid type along the length of the cable has a significant impact on the stability and drag forces that has not yet been extensively studied. A series of experimental investigations examining speed, acceleration, length of cable and path of motion were paired with predictions from a simulation for
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Čakanišin, Adrián, and Mária Halenárová. "Monte Carlo as a Method for Examining of Business Changes in Tourism in Slovakia." In 25th International Joint Conference Central and Eastern Europe in the Changing Business Environment. Vydavateľstvo EKONÓM, 2025. https://doi.org/10.53465/ceecbe.2025.9788022552257.50-63.

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The business environment in tourism encompasses a set of factors influencing the establishment, development, and sustainability of businesses in this sector, including economic, legislative, and market conditions. The dynamics of this environment are crucial for the economic stability of the sector. The main objective of this paper is to model the development of business establishments and closures in the tourism sector based on historical data and the influence of selected factors. The data used for this study were obtained from the Statistical Office of the Slovak Republic upon request. To a
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Abraham, J. J., C. Devers, C. Teodoriu, and M. Amani. "Scaling Field and Experimental Data Using Machine Learning Approaches to Evaluate Oilwell Cement Degradation, Stability and Integrity for CCUS Applications." In GOTECH. SPE, 2024. http://dx.doi.org/10.2118/219115-ms.

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Abstract Carbon Capture, Utilization and Storage (CCUS) processes are increasingly being utilized as a viable solution for carbon removal and meet the goal of net-zero carbon emissions by 2050. Captured carbon dioxide (CO2) is stored deep underground – typically in depleted oil or gas (O&amp;G) wells - utilizing technologies and methods currently employed by the energy industry. However, there are certain ongoing well integrity challenges that would need to be addressed – especially those relating to the cement layer. Cement present in wells used for CCUS applications – including old or abando
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Li, Deying, Yanping Song, Yunfeng Fu, Huanlong Chen, and Hiroharu Ooyama. "Numerical Investigation of Equilibrium Wet Steam Flow Property Based on S2 Calculation Code." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-25750.

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Though it is non-equilibrium wet steam flow in steam turbine, the droplets with micron dimension are usually not considered in the primary design of the steam turbine in the industrial application because the global properties of steam are concerned mostly. Two calculation models of equilibrium wet steam property are proposed and applied to the performance prediction of a one stage low pressure (LP) steam turbine with superheated vapor and a 1.5-stage LP steam turbine with superheated and saturation steam by the using of the central S2 stream surface calculation code developed in this paper. D
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Cancemi, Salvatore Angelo, Rosa Lo Frano, and Sandro Paci. "Preliminary Thermo-Mechanical Characterization of Cement-Based Materials for LLW Immobilization." In ASME 2023 International Conference on Environmental Remediation and Radioactive Waste Management. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/icem2023-110086.

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Abstract The aim of the study is to investigate the thermo-mechanical properties of cement-based materials for immobilization of low/intermediate level waste. The cementation is an important technology, nevertheless the durability of such waste form must be studied in consideration of the institutional period of storage or even under disposal conditions. Moreover, if liquid organic wastes are immobilized into cement matrix, we must face a significant technological challenge due to their complex chemical composition and relatively high activity. To investigate the durability of cement cement-ba
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Armin, Kueck, Everhard Eliah, Huang Xu, Valbuena Franklin, Reckmann Hanno, and Bomidi John. "Qualifying Bit Influence on High-Frequency Torsional Oscillations Based on Full-Scale Laboratory Experiments." In SPE/IADC International Drilling Conference and Exhibition. SPE, 2023. http://dx.doi.org/10.2118/212566-ms.

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Abstract High-Frequency-Torsional Oscillations (HFTO) generate dynamic loads that can damage drilling tools, resulting in, for example cracks, twist-offs or broken electronics. They are triggered by the interaction of bits and rocks and force operators to reduce rotary spped (RPM) and weight on bit (WOB) losing drilling performance in the process. Recently, a full-scale drilling test rig was proven to generate verified HFTO behavior under laboratory conditions (Everhard et. al. 2023). This rig allows for a comprehensive study of the influences of bit characteristics on HFTO for the first time.
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Reports on the topic "The developed method is stability indicating"

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Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was
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Conrady, Morgan, Markus Bauer, Kyoo Jo, Donald Cropek, and Ryan Busby. Solid-phase microextraction (SPME) for determination of geosmin and 2-methylisoborneol in volatile emissions from soil disturbance. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/42289.

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A method is described here for the concentration and determination of geosmin and 2-methylisoborneol (2-MIB) from the gaseous phase, with translation to field collection and quantification from soil disturbances in situ. The method is based on the use of solid-phase microextraction (SPME) fibers for adsorption of volatile chemicals from the vapor phase, followed by desorption into a gas chromatograph-mass spectrometer (GC-MS) for analysis. The use of a SPME fiber allows simple introduction to the GC-MS without further sample preparation. Several fiber sorbent types were studied and the 50/30 μ
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Pokrzywinski, Kaytee, Cliff Morgan, Scott Bourne, Molly Reif, Kenneth Matheson, and Shea Hammond. A novel laboratory method for the detection and identification of cyanobacteria using hyperspectral imaging : hyperspectral imaging for cyanobacteria detection. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/40966.

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To assist US Army Corps of Engineers resource managers in monitoring for cyanobacteria bloom events, a laboratory method using hyperspectral imaging has been developed. This method enables the rapid detection of cyanobacteria in large volumes and has the potential to be transitioned to aerial platforms for field deployment. Prior to field data collection, validation of the technology in the laboratory using monocultures was needed. This report describes the development of the detection method using hyperspectral imaging and the stability/reliability of these signatures for identification purpo
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Gehlhar, Mark. Reconciling Bilateral Trade Data for Use in GTAP. GTAP Technical Paper, 2000. http://dx.doi.org/10.21642/gtap.tp10.

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Bilateral trade flows are reported by both importers and exporters. Large discrepancies in reported import/export trade flows can be found when these two reports are compared. The GTAP database requires consistency between the export flow and its corresponding import flow for all partner pairs. Therefore, bilateral trade data in its reported form cannot be directly used for GTAP. Various methods can be used to produce a consistent set of bilateral trade flows. However, achieving consistency alone does not necessarily provide credible trade flows. Matrix balancing using trade totals published b
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Wang, Han, Issam Qamhia, Erol Tutumluer, and Youngdae Kim. Effectiveness of Geosynthetics in Soil/Aggregate Stabilization—Evaluation Using Bender Element Sensor Technology. Illinois Center for Transportation, 2025. https://doi.org/10.36501/0197-9191/25-007.

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This report presents laboratory evaluations of the effectiveness of geosynthetics in stabilizing unbound aggregate layers and develops design guidelines for using geosynthetic-stabilized pavements in Illinois. The research focused on quantifying benefits from geosynthetic mechanical stabilization and incorporating those benefits into pavement analysis and design procedures. An experimental program was conducted, including laboratory triaxial testing and large-scale test bed evaluations. Twelve geosynthetic products, including ten geogrids (integral or punched and drawn, welded, and woven) and
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D’Agostino, Martin, Nigel Cook, Liam O’Connor, et al. Optimising extraction and RT-qPCR-based detection of hepatitis E virus (HEV) from pork meat and products. Food Standards Agency, 2023. http://dx.doi.org/10.46756/sci.fsa.ylv958.

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Hepatitis E is an infection of the liver caused by the hepatitis E virus (HEV). HEV infection usually produces a mild disease, hepatitis E. However, disease symptoms can vary from no apparent symptoms to liver failure. There are 4 main types (genotypes) of the virus that cause concern in humans. Genotypes 1 and 2 infections are mainly restricted to humans but 3 and 4 can be identified in numerous other animal species including pigs. Transmission routes of HEV genotypes 3 and 4 have been identified to include the consumption of food products derived from infected animals and shellfish, and via
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Michelmore, Richard, Eviatar Nevo, Abraham Korol, and Tzion Fahima. Genetic Diversity at Resistance Gene Clusters in Wild Populations of Lactuca. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7573075.bard.

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Genetic resistance is often the least expensive, most effective, and ecologically-sound method of disease control. It is becoming apparent that plant genomes contain large numbers of disease resistance genes. However, the numbers of different resistance specificities within a genepool and the genetic mechanisms generating diversity are poorly understood. Our objectives were to characterize diversity in clusters of resistance genes in wild progenitors of cultivated lettuce in Israel and California in comparison to diversity within cultivated lettuce, and to determine the extent of gene flow, re
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Singhvi, Punit, Javier García Mainieri, Hasan Ozer, and Brajendra Sharma. Rheology-Chemical Based Procedure to Evaluate Additives/Modifiers Used in Asphalt Binders for Performance Enhancements: Phase 2. Illinois Center for Transportation, 2021. http://dx.doi.org/10.36501/0197-9191/21-020.

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The increased use of softer binders in Illinois over the past decade is primarily attributed to the increased use of recycled materials in asphalt pavement construction. The shift in demand of using PG 58-28 over PG 64-22 has resulted in potential alternative methods to produce softer binders more economically using proprietary products. However, there are challenges in using these proprietary products for asphalt modification because of uncertainty in their long-term performance and significant variability in binder chemistry. The current SuperPave performance grading specification for asphal
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Litaor, Iggy, James Ippolito, Iris Zohar, and Michael Massey. Phosphorus capture recycling and utilization for sustainable agriculture using Al/organic composite water treatment residuals. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7600037.bard.

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Objectives: 1) develop a thorough understanding of the sorption mechanisms of Pi and Po onto the Al/O- WTR; 2) determine the breakthrough range of the composite Al/O-WTR during P capturing from agro- wastewaters; and 3) critically evaluate the performance of the composite Al/O-WTR as a fertilizer using selected plants grown in lysimeters and test-field studies. Instead of lysimeters we used pots (Israel) and one- liter cone-tainers (USA). We conducted one field study but in spite of major pretreatments the soils still exhibited high enough P from previous experiments so no differences between
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Grumet, Rebecca, and Benjamin Raccah. Identification of Potyviral Domains Controlling Systemic Infection, Host Range and Aphid Transmission. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7695842.bard.

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Potyviruses form one of the largest and most economically important groups of plant viruses. Individual potyviruses and their isolates vary in symptom expression, host range, and ability to overcome host resistance genes. Understanding factors influencing these biological characteristics is of agricultural importance for epidemiology and deployment of resistance strategies. Cucurbit crops are subject to severe losses by several potyviruses including the highly aggressive and variable zucchini yellow mosaic virus (ZYMV). In this project we sought to investigate protein domains in ZYMV that infl
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