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1

Meid, Andreas D., Camilo Scherkl, Michael Metzner, David Czock, and Hanna M. Seidling. "Real-World Application of a Quantitative Systems Pharmacology (QSP) Model to Predict Potassium Concentrations from Electronic Health Records: A Pilot Case towards Prescribing Monitoring of Spironolactone." Pharmaceuticals 17, no. 8 (2024): 1041. http://dx.doi.org/10.3390/ph17081041.

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Quantitative systems pharmacology (QSP) models are rarely applied prospectively for decision-making in clinical practice. We therefore aimed to operationalize a QSP model for potas-sium homeostasis to predict potassium trajectories based on spironolactone administrations. For this purpose, we proposed a general workflow that was applied to electronic health records (EHR) from patients treated in a German tertiary care hospital. The workflow steps included model exploration, local and global sensitivity analyses (SA), identifiability analysis (IA) of model parameters, and specification of their inter-individual variability (IIV). Patient covariates, selected parameters, and IIV then defined prior information for the Bayesian a posteriori prediction of individual potassium trajectories of the following day. Following these steps, the successfully operationalized QSP model was interactively explored via a Shiny app. SA and IA yielded five influential and estimable parameters (extracellular fluid volume, hyperaldosteronism, mineral corticoid receptor abundance, potassium intake, sodium intake) for Bayesian prediction. The operationalized model was validated in nine pilot patients and showed satisfactory performance based on the (absolute) average fold error. This provides proof-of-principle for a Prescribing Monitoring of potassium concentrations in a hospital system, which could suggest preemptive clinical measures and therefore potentially avoid dangerous hyperkalemia or hypokalemia.
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Elashry, A., and C. Toth. "IMPROVING CAMERA POSE ESTIMATION USING SWARM PARTICLE ALGORITHMS." International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLVIII-M-3-2023 (September 5, 2023): 87–93. http://dx.doi.org/10.5194/isprs-archives-xlviii-m-3-2023-87-2023.

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Abstract. Most computer vision and photogrammetry applications rely on accurately estimating the camera pose, such as visual navigation, motion tracking, stereo photogrammetry, and structure from motion. The Essential matrix is a well-known model in computer vision that provides information about the relative orientation between two images, including the rotation and translation, for calibrated cameras with a known camera matrix. To estimate the Essential matrix, the camera calibration matrices, which include focal length and principal point location must be known, and the estimation process typically requires at least five matching points and the use of robust algorithms, such as RANSAC to fit a model to the data as a robust estimator. From the usually large number of matched points, choosing five points, the Essential matrix can be determined based on a simple solution, which could be good or bad. Obtaining a globally optimal and accurate camera pose estimation, however, requires additional steps, such as using evolutionary algorithms (EA) or swarm algorithms (SA), to prevent getting trapped in local optima by searching for solutions within a potentially huge solution space.This paper aims to introduce an improved method for estimating the Essential matrix using swarm particle algorithms that are known to efficiently solve complex problems. Various optimization techniques, including EAs and SAs, such as Particle Swarm Optimization (PSO), Gray Wolf Optimization (GWO), Improved Gray Wolf Optimization (IGWO), Genetic Algorithm (GA), Salp Swarm Algorithm (SSA) and Whale Optimization Algorithm (WOA), are explored to obtain the global minimum of the reprojection error for the five-point Essential matrix estimation based on using symmetric geometric error cost function. The experimental results on a dataset with known camera orientation demonstrate that the IGWO method has achieved the best score compared to other techniques and significantly speeds up the camera pose estimation for larger number of point pairs in contrast to traditional methods that use the collinearity equations in an iterative adjustment.
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Feri, Rose, Marcellus Simadibrata, and Anwar Jusuf. "Self-Assessment dalam Kegiatan Diskusi Problem-Based Learning Fakultas Kedokteran: Kajian Naratif." Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education 4, no. 3 (2015): 122. http://dx.doi.org/10.22146/jpki.25284.

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Background: Student peformance assessment during problem-based learning (PBL) discussion is still debatable. One of the assessments that applies adult learning principle is self-assessment (SA). In fact, many medical schools prefer to use tutor assessment than SA because it is considered less accurate. Many studies have reported that the accuracy of SA is poor because of their own lack of knowledge and SA skills. This literature review aims to explore deeper in SA and its basic principles in designing SA instrument for PBL discussion in medical school.Method: This study was conducted using narrative review method. Ten articles were reviewed. Five articles were chosen from google search engine and the other five from medical education textbooks.Results: SA is the ability of a student to observe, analyze and assess his own performance based on the criteria and he determines a way to fix it. SA skills that have been practiced during PBL discussions will equip the students to become future health professionals who are competent in determining their own continuous professional development (CPD) programs. When designing a SA instrument, one needs to explore these five main issues, including acceptance, accuracy, power, feasibility and context.Conclusion: SA is the most effective assessment to assess a student’s achievement in PBL discussion if implemented properly. The completion of SA should be made in the normal context and one must explore the five main issues constantly so that SA can be done properly and well.
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Peng, Bao Ying, and Qiu Shi Han. "NURBS Curve Design and CNC Machining Principle." Applied Mechanics and Materials 141 (November 2011): 392–96. http://dx.doi.org/10.4028/www.scientific.net/amm.141.392.

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Used fixed equal step cubic spline interpolation in non-circular machining, the influence of acceleration may be too strong to cause burns and vibration. To suppress the acceleration influence of feed axis, take cam grinding as an illustration, first derived acceleration and its change from the cubic spline function, then adopting the method of off-line fuzzy model logical reasoning combined with five points of three power smooth, obtained the modified variable interpolation time steps. The experiment results that the feed axis acceleration stability used fuzzy step cubic spline interpolations is much better than equal step spline in cam grinding under the same processing efficiency.
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PARASURAMAN, S., ARIF WICAKSONO OYONG, and VERONICA LESTARI JAUW. "ROBOT ASSISTED STROKE REHABILITATION: JOINT TORQUE/FORCE CONVERSION FROM EMG USING SA PROCESS." Journal of Mechanics in Medicine and Biology 11, no. 03 (2011): 691–704. http://dx.doi.org/10.1142/s0219519411004368.

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This paper focuses on the implementation of robot-assisted stroke rehabilitation using electromyography (EMG) as the interface between the robot and subjects. The key issue in implementing EMG for this application is the conversion process of EMG signal into torque/force, which is used as a input to the control system. This paper presents a methodology of EMG signal conversion into estimated joint torque by using simulated annealing (SA) technique. Basic principle of SA, formulation, and implementation to the problem are discussed in this paper. Experimental studies with real life EMG data have been carried out for five subjects. These studies are used to evaluate the feasibility of the methodology proposed for robot-assisted stroke rehabilitation problem. Experimental investigations and results are discussed at the end of the paper.
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Smith, John D., and Gary Guerra. "Quantifying Step Count and Oxygen Consumption with Portable Technology during the 2-Min Walk Test in People with Lower Limb Amputation." Sensors 21, no. 6 (2021): 2080. http://dx.doi.org/10.3390/s21062080.

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Step counts and oxygen consumption have yet to be reported during the 2-min walk test (2MWT) test in persons with lower-limb amputations (LLA). The purpose of this study was to determine step counts and oxygen consumption during the 2MWT in LLA. Thirty-five men and women walked for two minutes as quickly as possible while wearing activity monitors (ActiGraph Link on the wrist (LW) and ankle (LA), Garmin vivofit®3 on the wrist (VW) and ankle (VA), and a modus StepWatch on the ankle (SA), and a portable oxygen analyzer. The StepWatch on the ankle (SA) and the vivofit3 on the wrist (VW) had the least error and best accuracy of the activity monitors studied. While there were no significant differences in distance walked, oxygen consumption (VO2) or heart rate (HR) between sexes or level of amputation (p > 0.05), females took significantly more steps than males (p = 0.034), and those with unilateral transfemoral amputations took significantly fewer steps than those with unilateral transtibial amputations (p = 0.023). The VW and SA provided the most accurate step counts among the activity monitors and were not significantly different than hand counts. Oxygen consumption for all participants during the 2MWT was 8.9 ± 2.9 mL/kg/min, which is lower than moderate-intensity activity. While some may argue that steady-state activity has not yet been reached in the 2MWT, it may also be possible participants are not walking as fast as they can, thereby misclassifying their performance to a lower standard.
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Yang, Zhenyu, Liyuan Zhang, and Zhou Gao. "Development of preliminary design of the energy system of the Ningdong, Ningxia thermal power plant." E3S Web of Conferences 458 (2023): 01018. http://dx.doi.org/10.1051/e3sconf/202345801018.

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The purpose of this design is to master the basic steps, calculation methods, and equipment selection methods of the thermal power system of the thermal power plant, and to familiarize with the composition, connection, and operation characteristics of the thermal power system through the preliminary design of 600MW thermal power plant thermal power plant. This paper is divided into five parts, selecting the principle thermal system formulation, calculating the principle thermal system, the selection of unit auxiliary equipment, steam pipeline calculation, and selection after and after successful calibration. The preliminary design of the thermal system is completed by drawing the comprehensive thermal system diagram and the local system diagram using the above calculation data.
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Chen, Qi, Wenfeng Tian, Wuwei Chen, Qadeer Ahmed, and Yanming Wu. "Model-Based Fault Diagnosis of an Anti-Lock Braking System via Structural Analysis." Sensors 18, no. 12 (2018): 4468. http://dx.doi.org/10.3390/s18124468.

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The anti-lock braking system (ABS) is an essential part in ensuring safe driving in vehicles. The Security of onboard safety systems is very important. In order to monitor the functions of ABS and avoid any malfunction, a model-based methodology with respect to structural analysis is employed in this paper to achieve an efficient fault detection and identification (FDI) system design. The analysis involves five essential steps of SA applied to ABS, which includes critical faults analysis, fault modelling, fault detectability analysis and fault isolability analysis, Minimal Structural Over-determined (MSO) sets selection, and MSO-based residual design. In terms of the four faults in the ABS, they are evaluated to be detectable through performing a structural representation and making the Dulmage-Mendelsohn decomposition with respect to the fault modelling, and then they are proved to be isolable based on the fault isolability matrix via SA. After that, four corresponding residuals are generated directly by a series of suggested equation combinations resulting from four MSO sets. The results generated by numerical simulations show that the proposed FDI system can detect and isolate all the injected faults, which is consistent with the theoretical analysis by SA, and also eventually validated by experimental testing on the vehicle (EcoCAR2) ABS.
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Shadiq, Fadjar. "What Can We Learn from the ELPSA, SA, and PSA Frameworks? The Experience of SEAQiM." Southeast Asian Mathematics Education Journal 7, no. 1 (2017): 65–76. http://dx.doi.org/10.46517/seamej.v7i1.46.

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One of education problems in Indonesia according to Dr. Anies Baswedan, the former Minister of Education and Culture of the Republic of Indonesia, was: “How to help Indonesian students to be independent learners and have good characters?” This question then raises an issue: “What kinds of knowledge, skills, and attitudes are needed by our students to survive in the 21st Century and beyond?” Earlier the author stated (Shadiq, 2016a) that to change and improve the quality of the teaching and learning process from a ‘typical’ or ‘traditional’ mathematics classroom to a more innovative one was not easy. Afurther issue was: “How to change real teaching practice?” Mathematics teachers need to experience ways that they will be expected to implement in their teaching. Isoda (2011) proposed a Problem Solving Approach (PSA) which consists of four steps: (1) problem posing, (2) independent solving, (3) comparison and discussion, and (4) summary and integration. In Indonesia, we can learn from Scientific Approach (SA) which covers five steps: (1) observing, (2) questioning, (3) collecting data or experimenting, (4) reasoning, and (5) communicating. In addition, Lowrie and Patahuddin (2015) proposed Experiences, Language, Pictures, Symbols, Application (ELPSA) as a lesson design framework for mathematics teaching and learning process. A problem is examined based on these three frameworks where at least 11 alternatives can be identified to solve it. The paper ends with some recommendations on how to improve Indonesian mathematics teaching.
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Purnamawati, Frimha, and Rizqi Fajar Pradipta. "TRANSFORMATIVE LEARNING MODEL FOR PARENTING EDUCATION PROGRAM." Journal Of Educational Experts (JEE) 5, no. 1 (2022): 13. http://dx.doi.org/10.30740/jee.v5i1p13-20.

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The purpose of this study is to produce a transformative learning model in parenting education programs organized by early childhood education institutions in changing the terms of reference for children's education to be even better and in synergy with those carried out by educational institutions. This research includes development model research. The results of this study are a transformative learning model in a parenting education program that uses five components, namely (1) syntax; (2) Social System; (3) Reaction Principle; (4) Support System and (5) Instructional Impact and Accompaniment. The steps of Transformative Learning used in the parenting education process consist of 4 steps of field activities, namely: (1) problem development steps; (2) critical reflection development steps; (3) location of determination and implementation of action; and (4) assistance steps taken by educators of early childhood education institutions to early childhood parents in the form of consultations, group discussion activities, and face-to-face activities (class sessions). The success of transformative learning in this parenting education program is that there is a change in the frame of reference of the parents of early childhood which comes from themselves, and the function of educators in this transformative learning process is as a facilitator and counselor in helping towards the change process.
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11

Lakshmi, R., and Pramod Gopinath. "Nonlinear optical properties of AIE doped PMMA thin film upon restriction of intramolecular motion." Journal of Physics: Conference Series 2357, no. 1 (2022): 012014. http://dx.doi.org/10.1088/1742-6596/2357/1/012014.

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Aggregation Induced Emission (AIE) is an interesting Photophysical phenomenon in which a series of molecules non-emissive in solution state become fluorescent upon aggregation or by structural rigidification. Restriction of intramolecular motion (RIM) is the basic principle of this phenomenon. Nonlinear absorption properties of AIE dye named Tertraphenylethylene (TPE) in Anisole and doping it in PMMA matrix is studied using Open Apperture (OA) Z-scan technique. OA Z-scan trace of TPE in anisole showed RSA in SA behaviour due to two photon induced excited state absorption while TPE doped PMMA film showed RSA behaviour with two photon absorption (TPA) as an underlying mechanism. Five level energy model is used to understand this change in nonlinearity. Optical limiting threshold shows only a slight change upon RIM.
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12

Sijia, Xue, Guo Yanling, Li Jingzhi, Ke Shaoyong, and Duan Liping. "Synthesis and biological activity of N'-(substituted pyrimidin-2-yl)- N-dichlorochrysanthemoyl thioureas and their fused heterocyclic compounds." Journal of Indian Chemical Society Vol. 82, Mar 2005 (2005): 262–64. https://doi.org/10.5281/zenodo.5827025.

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College of Life-and Environmental Science, Department of Chemistry, Shanghai Normal University, Shanghai, 200234, P. R. China <em>E-mail</em> : ylguo420@ 163.com <em>Manuscript received 25 June 2004, accepted 24 November 2004</em> Five <em>N&#39;</em> -(substituted pyrimidin-2-yi)-<em>N</em>-dichlorochrysanthemoyl thioureas (Sa-Se) were synthesized from corresponding dichlorochrysanthemic acid in three steps. And two dichlorochrysanthemoylimino-2<em>H</em>-1,2,4-thiadiazolo[2,3-a]pyrimidines were prepared by oxidizing cyclization of 5a, 5b. The structures of these novel target compounds were confirmed by IR, <sup>1</sup>H NMR and elemental analyses. The preliminary biological activity tests indicated that some target compounds had better insecticidal activity, fungicidal activity and so on multiple efficacies.
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McDermott, Martina S. J., Neil Conlon, Brigid C. Browne, et al. "HER2-Targeted Tyrosine Kinase Inhibitors Cause Therapy-Induced-Senescence in Breast Cancer Cells." Cancers 11, no. 2 (2019): 197. http://dx.doi.org/10.3390/cancers11020197.

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Prolonged treatment of HER2 positive breast cancer cells with tyrosine kinase inhibitors (TKIs) leads to the emergence of acquired resistance. However, the effects of continuous TKI exposure on cell fate, and the steps leading to the acquisition of a resistant phenotype are poorly understood. To explore this, we exposed five HER2 positive cells lines to HER2 targeted therapies for periods of up to 4 weeks and examined senescence associated β-galactosidase (SA-β-gal) activity together with additional markers of senescence. We found that lapatinib treatment resulted in phenotypic alterations consistent with a senescent phenotype and strong SA-β-gal activity in HER2-positive cell lines. Lapatinib-induced senescence was associated with elevated levels of p15 and p27 but was not dependent on the expression of p16 or p21. Restoring wild type p53 activity either by transfection or by treatment with APR-246, a molecule which reactivates mutant p53, blocked lapatinib-induced senescence and caused increased cell death. In contrast to lapatinib, SA-β-gal activity was not induced by exposing the cells to trastuzumab as a single agent but co-administration of lapatinib and trastuzumab induced senescence, as did treatment of the cells with the irreversible HER2 TKIs neratinib and afatinib. Neratinib- and afatinib-induced senescence was not reversed by removing the drug whereas lapatinib-induced senescence was reversible. In summary, therapy-induced senescence represents a novel mechanism of action of HER2 targeting agents and may be a potential pathway for the emergence of resistance.
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Munjin Nasih, Ahmad. "Pergeseran pola maqasid al-shari‘ah dari tradisional menuju modern: membaca pemikiran Jasser Auda." Ijtihad : Jurnal Wacana Hukum Islam dan Kemanusiaan 11, no. 1 (2011): 1. http://dx.doi.org/10.18326/ijtihad.v11i1.1-20.

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In study of Islamic law there is an interesting topic to discuss, that is maqasid al-shari‘ah. Recently some Muslim scholars study further the applying of principle of daruriyat al-khamsah in a legal problem. Unfortunately Islamic jurists often apply the principle of daruriyat al-khamsah independently apart from other sciences besides usul al-fiqh. Difficulties and failure in deciding many contemporary legal problems rise to the result. Jasser Audah, a Muslim scholar from Egypt and lives in London proposes new idea to cope with this problem. According to Audah, at first we must separate maqasid al-shari‘ah from usul alfiqh in order to be independent knowledge. Then we combine it with modern sciences in studying legal problem. Only through this method, Auda believes that Islamic law will be more adaptable with the changing situation. In order to do his idea in developing maqasid al-shari‘ah, Auda specifically suggests five steps, that are: validating all cognitios, holism, openness and self-renewal, multi-dimensionality, and purposefulness.
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Juliastuti, Putri, Suryadi Suryadi, and Ngudining Rahayu. "PRINSIP KERJA SAMA PERCAKAPAN DI KANTOR IMIGRASI KELAS 1 BENGKULU." Jurnal Ilmiah KORPUS 2, no. 1 (2018): 93–100. http://dx.doi.org/10.33369/jik.v2i1.5561.

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This research aims to describe the forms of compliance and violation of cooperation principle which have been occurred at Class 1 of Bengkulu Immigration Office. This research is a qualitative descriptive research. Sources of data in this research were officers and applicants. This research data was a speech event that it told by officers and applicants which contain of cooperation principle in it. Data collection was conducted start from date March 20th until April 6th, 2017. The instrument used in this research were a human instrument with hardware tools in the form of notebooks and smartphones, and software such as limitation and understanding maxims of conversation/cooperation principle (maxim quantity, maxim quality, maxim relevance, and maxim manner. Data collected by recording technique and note technique. Data analysis were done by steps as follow; data transcription, data identification, data classification, data interpretation, data validation, and data conclusion. The results of this research showed that two conclusions. First, the forms of compliance with the cooperation principle which have been occurred at center of Class 1 of Bengkulu Immigration Service which consist from four maxims based on Grice maxim and six maxims of mixed results between the maxim of quantity, quality, relevance, and manner were found when conducting research in the field. Second is the forms of violation of cooperation principle at center of Class 1 of Bengkulu Immigration Service which consist from four maxims based on Grice maxim and five maxims mixed found when conducting research in the field. Keywords: Cooperation Principle, Conversation, Maxim
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Stepukonis, Aivaras. "Re-Thinking Cultural Hedonism." Dialogue and Universalism 33, no. 1 (2023): 181–94. http://dx.doi.org/10.5840/du202333111.

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Hedonism, driven by mass culture and widespread consumerism, is a salient factor in the modus vivendi of contemporary Western civilization. This general psychological and behavioral backdrop is exploited in the article as an opportunity to both reinvigorate and re-appraise the theoretical underpinnings of modern hedonism as developed by John Stuart Mill in his Utilitarianism. The article proceeds in two steps: Firstly, a detailed exposition of Mill’s arguments for the principle of utility is undertaken, with an accompanying elucidation of the core notions of utility, expediency, happiness, and pleasure. Secondly, five points of criticism (logical, phenomenological, and analytical in method) are raised to challenge what the author thinks are the weakest links in Mill’s syllogistic chain.
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Hidayat Ur Rehman, Dr. Syed Raza Shah Gilani, and Dr. Ilyas Khan. "Rule of Law and the Doctrine of Proportionality; Appraisal, Rational and Validation." sjesr 4, no. 1 (2021): 222–29. http://dx.doi.org/10.36902/sjesr-vol4-iss1-2021(222-229).

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In Germany, many researchers – including judges – believe that the idea of proportionality should stem from the notion of Rechsstaat. The term, when translated into English, is Rule of Law, and “Etat de Droit” in French. Applying the rule of law as a reason for adopting proportionality as a factor for limiting constitutional rights via the constitutionality of sub-constitutional law has also been implemented by other legal organizations. To understand the liaison connecting the rule of law and the doctrine of proportionality, it is essential to determine whether the proportionality could have a harmony with the values of rule of law in five steps. First, it is necessary to enquire whether the rule of law principle has a constitutional position. Next, it must be determined whether the rule of law as a principle of the constitution includes a feature of Human Rights. Third, we must ascertain whether the rule of law, as a principle of the constitution, is based upon an equilibrium amid constitutional rights and their limitations. Fourth, it must be determined that such a balance is conducted through the use of limitation clauses (statutes or the common law). Fifth, it is essential to establish an opinion on whether limitation clauses, which advance the standard of the rule of law, are based on proportionality.
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PRASONGTHAN, Supaporn, and Rabhas SILPSRIKUL. "THE CONNECTION OF SLOW FOOD PRINCIPLE WITH COMMUNITY- BASED TOURISM IN THAILAND: INVESTIGATING GENERATION Y PERCEPTION." GeoJournal of Tourism and Geosites 48, no. 2 supplement (2023): 709–16. http://dx.doi.org/10.30892/gtg.482spl04-1070.

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The slow food movement, a new gastronomic trend, arisen as a striking response to negative impacts of globalization with three principles of “Good, Fair and Clean. Community-based tourism covers a variety of local culture, especially local food products, services, and experiences. As the generation Y cohort represents a significant market for tourists, this article aims to explore the connection between slow food principle and community-based tourism, and evaluate slow food attributes that need to be improved related to Gen Y perspective. A questionnaire was used to collect data with 385 respondents. Five steps of the importance-performance analysis were evaluated to acquire reliability and validity issues. The findings imply the slow food principle associated with CBT food-related activities with high level of perceived importance and performance. The results of IPA reveal that the quality of food in CBT destination needs to be urgently managed to establish a memorable experience. A collaboration among CBT enterprises, government, private sector, and marketers to strengthen public awareness about slow food could be one of steppingstone toward sustainable development and healthy food culture.
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Pan, Chenghao. "Solar Active Layer Materials and Research Progress." Highlights in Science, Engineering and Technology 106 (July 16, 2024): 459–65. http://dx.doi.org/10.54097/dqw8xg56.

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Solar cell is an electrical device, which converts the light energy into electrical energy through the photovoltaic (PV) effect. It is an efficient way to alleviate global warming effect. This work explains the principle and the structure of OPV. There are mainly five layers of OPV and five steps of how OPV works. Besides, a brief review of the history of OPV’s development is given in this work. As a matter of fact, the active layer is the most important part of the solar cell. It directly determines the conversion efficiency of solar cell. The stucture of active layer is shown in the paper as well. The active layer is divided into two main categories: organic and inorganic. The research progress of each type of active layer is illustrated in this work. A detailed description of the types of active layer of solar cell and the pros and cons of each type are given in this work.
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Lacour, Philippe. "Signification et réflexivité dans la philosophie de Ricœur." Études Ricoeuriennes / Ricoeur Studies 11, no. 1 (2020): 86–116. http://dx.doi.org/10.5195/errs.2020.497.

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In this article, I investigate Ricœur’s definition of philosophy by addressing two of its most fundamental conditions: meaning, which somehow constitutes its inner material, and reflexivity, which is the principle of its dynamic articulation. I proceed in two steps. First, I distinguish five different levels of discourse, underlining the originality of each of them: descriptive, transphrastic, self-comprehensive, anthropological, metaphysical. Then I explain the role played by reflexivity, both in its intra- and inter-semiotic dimension, in delimitating these various levels and helping the transition from one to another. In conclusion, I show that the whole of Ricœur’s philosophy can be characterized by a confidence in language, in its both obstinate and cautious effort to “enlighten existence” by pushing the limits of its fontiers.
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Fakhruddin, Anas. "Kontra Ideologi Terorisme Menurut Nahdlatul Ulama dan Muhammadiyah di Lamongan." JRP (Jurnal Review Politik) 7, no. 1 (2017): 181–209. http://dx.doi.org/10.15642/jrp.2017.7.1.181-209.

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This article explained how the two major organizations Muhammadi­yah and Nahdlatul Ulama addressing steps fundamentalist groups in Lamongan. Muhammadiyah change the pattern of motion to promote and conduct large-scale reproduction for the muballigh. Muhammadi­yah accommodated in preachers bank. And expanding missionary that has been more advanced aspects of speech to the missionary movement that led to the context aspect, which contains the values ??of action. While NU through Nahdliyah fikrah principle has five characteristics, namely: 1). Moderate, 2). Tolerant, 3). Reformative 4). Dynamic 5). Metho­­­do­lo­gical mindset. Both organizations have equal society in terms of doing routine for Improving the quality of the religious with the aim of fortifying the community of Islam to understand the influence of non Ahlus Sunnah wal Jama'ah
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Newman, Saul. "Anarcho-Cosmopolitanism: Towards a New Ethos of Hospitality." Revista Portuguesa de Filosofia 78, no. 4 (2023): 1407–30. http://dx.doi.org/10.17990/rpf/2022_78_4_1407.

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This paper develops a new understanding of hospitality on the basis of an anarchist philosophy of cosmopolitanism. It is argued that anarchism – in its radical critique of the principle of sovereignty and sovereign ipseity – is primarily a philosophy and politics of hospitality. The argument proceeds in five key steps. Firstly, the relationship between ontological anarchism (Schürmann and Levinas) and political anarchism (Bakunin, Kropotkin, Proudhon, Godwin) is explored. Secondly, anarchism’s critique of nation state sovereignty is linked to a radical cosmopolitanism based on cross-border solidarity, mutual aid, and human rights activism, including the defence of the rights of migrants and asylum seekers. Thirdly, I show how the anarchic subject cannot be reduced to a fixed or definable identity with closed borders, but, rather, embodies an attitude of hospitality towards the Other and an openness to being transformed by this encounter. On this basis, I aim to develop an anarchist ethics formulated around the idea of care – for the other, both human and non-human, for the world, for the natural environment (Four) – and an alternative cosmopolitan ethical and political horizon (Five).
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Heo, Hoon. "The five-element principle as a Philosophy at Sa-Sang Constitutional Medicine - The point of views of the Lee eul-ho(李乙浩) -". Korean Journal of Philosophy 128 (31 серпня 2016): 1. http://dx.doi.org/10.18694/kjp.2016.08.128.1.

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LEȘTARU, Marius. "PRE-ESTABLISHED FIGHTING EXERCISES IN FIVE STEPS FOR PHYSICAL EDUCATION LESSONS, SPECIFICALLY KARATE-DO, BUCHAREST UNIVERSITY." UNIVERSITY ARENA 1, no. 1/2018 (2018): 36–38. https://doi.org/10.62229/uai_1_18-6.

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Premises. During the physical education Karate-Do lessons and also for the grade examination for the yellow belt at the end of the first year of University, the students will include in their current practice the pre-established five steps fighting exercises (Japanese: Gohon Kumite). Progress in Karate-Do will be established the same as in others physical education disciplines, following the principle of accessibility, by applying the three classical rules of didactic practice: from easy to difficult, from simple to complex and from known to unknown. The first step of Karate-Do is to correctly learn the fighting techniques by exercising alone, without a partner (Jap.: Kihon). The second step is to apply them by fighting one or more adversaries (Jap.: Kumite). By practicing the fighting exercises with a Karate-Do partner one can also attain the specific principals of physical education, by bettering physical development and motric capacities. A very important factor during the physical exercises will be the mental side, the student developing in short time understanding for the other side, for the activity immersion, for controlling emotions and techniques, for focusing one’s mind better and for will strength and developing a fighting spirit. Objectives. Internalizing the basic techniques for attacking and defense, controlling the breathing techniques, moving the body in the right sequence. Mentally, we will look for controlling emotions, fighting spirit, trusting yourself and determination. Methods. The method used for this presentation concerning the specific Gohon Kumite exercises, practiced by the Japan Karate Association will also be used by the students of The University of Bucharest in the first year of studies. The fore mentioned practice techniques are available for all the basic techniques to help attain the desired objectives. Conclusions. During the lessons with the students of the University of Bucharest, an important step is fighting one or more partners, following the Gohon Kumite exercises. By exercising these techniques, students will develop mental capacity, motric qualities, rhythm, breathing and following the right steps to attain the right techniques. Corectly practiced, the Gohon Kumite exercises will form a solid base for the next fighting techniques needed in superior levels of instruction and knowledge, by helping the formation of a strong fighting spirit and a strong, focused mind.
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Mardiah, Zaqiatul, Afdol Tharik Wastono та Abdul Muta’ali. "A COGNITIVE PERSPECTIVE ON THE ARABIC SPATIAL NOUN/ فَوْقَ /FAWQA/ APPLYING THE PRINCIPLE POLYSEMY MODEL". Paradigma: Jurnal Kajian Budaya 9, № 2 (2019): 154. http://dx.doi.org/10.17510/paradigma.v9i2.286.

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&lt;p class="TeksAbstrak"&gt;The present paper provides a cognitive linguistics (CL) framework for analyzing the semantic structure of Arabic spatial noun &lt;em&gt;fawqa&lt;/em&gt; based on &lt;em&gt;Principled Polysemy Model &lt;/em&gt;(PPM) of Tyler and Evans (2003). PPM approach can broaden the narrow view of classical cognitive linguists regarding the semantic variation in the concept of physical-geometry of a preposition. As a polysemous lexeme,&lt;em&gt; fawqa&lt;/em&gt; used by Arabian native to express a broad range of meanings, not only spatial relation but also non-spatial relation. The substantial sense of the lexeme is investigated using a large amount of corpus data (&lt;em&gt;corpus.kacst.edu.sa&lt;/em&gt;) and applying the five steps of PPM approach. Through this approach, we ascertain that every single usage of &lt;em&gt;fawqa &lt;/em&gt;expressing extended senses is always in its semantic network. Our study reveals that the usages of this lexeme in many situations and many cases show non-up down spatial relation, and non-physical relation, but they essentially refer to the primary sense.&lt;/p&gt;
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Srivastav, Aditi, Melissa Strompolis, Amy Moseley, and Kelsay Daniels. "The Empower Action Model: A Framework for Preventing Adverse Childhood Experiences by Promoting Health, Equity, and Well-Being Across the Life Span." Health Promotion Practice 21, no. 4 (2019): 525–34. http://dx.doi.org/10.1177/1524839919889355.

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The empower action model addresses childhood adversity as a root cause of disease by building resilience across multiple levels of influence to promote health, equity, and well-being. The model builds on the current evidence around adverse childhood experiences and merges important frameworks within key areas of public health—the socio-ecological model, protective factors, race equity and inclusion, and the life course perspective. The socio-ecological model is used as the foundation for this model to highlight the multilevel approach needed for improvement in public health. Five key principles that build on the protective factors literature are developed to be applied at each of the levels of the socio-ecological model: understanding, support, inclusion, connection, and growth. These principles are developed with actions that can be implemented across the life span. Finally, actions suggested with each principle are grounded in the tenets of race equity and inclusion, framing all actionable steps with an equity lens. This article discusses the process by which the model was developed and provides steps for states and communities to implement this tool. It also introduces efforts in a state to use this model within county coalitions through an innovative use of federal and foundation funding.
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Duret, Christophe. "Five more steps and you will be a new person: the procedural closure of the experiential field in Every Day the Same Dream." Comunicação e Sociedade 27 (June 29, 2015): 115–32. http://dx.doi.org/10.17231/comsoc.27(2015).2092.

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This paper will provide an analysis of the editorial game Every Day the Same Dream (EDSD). EDSD assumes the specific characteristics of a thesis novel (a “thesis game”, in this specific case) which Suleiman (1983: 1) defined as a type of novel which explicitly puts forth “recognized body of doctrine or system of ideas” and which has an “unambiguous dualistic system of values [...] rules of action addressed to the reader [and a] doctrinal intertext” (Suleiman, 1983: 54). According to the principle of procedural rhetoric (Bogost, 2008), the thesis of EDSD is mainly defended through the formal structure of the game, especially in the problem solving processes performed by the player. We therefore analyze EDSD as a thesis game by putting forward the concept of “micro-apparatus of procedural closure of the experiential field”, which arises from the meeting of hermeneutic and cognitive sciences, the objective being to describe the strategies used to disseminate a persuasive message among players and to analyze its reception.
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Li, Jianying, Qizheng Zhang, Yang Zhang, Chen Peng, and Yu Yang. "Modeling and Simulation Analysis of Speed-Regulating Valve Flow Fluctuations under Differential Pressure Steps." Electronics 11, no. 16 (2022): 2580. http://dx.doi.org/10.3390/electronics11162580.

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As an important component of the movement speed adjustment components of the executive elements in a hydraulic system, the speed-control valve should have good dynamic response ability and dynamic and static flow stability. In the working state, due to the fluctuation of oil supply pressure, load variation, valve spool movement, force variation, etc., the pressure difference between the inlet and outlet of the speed-regulation valve is prone to a step response. Due to the nonlinear relationship between the flow and pressure, the phenomenon of instantaneous fluctuations in the controlled flow occurs, which in turn leads to the unstable phenomenon of the speed of the execution element. Based on the working principle of the internal core components of a speed-control valve with a pressure compensation function, this study establishes a dynamic mathematical model of the valve, which is analyzed using AMEsim software. Aiming at the key problem of sudden changes in the differential pressure steps, the characteristics of a speed-regulation valve are analyzed in relation to the differential pressure increment, spring stiffness, spring preload, and initial opening of the pressure compensator and its viscous damping coefficient. The influence of the above five variables on the flow fluctuation is studied and a reasonable parameter adjustment range is given. The simulation and analysis results provide strong theoretical support for the performance and parameter optimization configuration of the speed-regulation valve.
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Luu, Phuong Thi, Ji-Young Lee, Ji-Heon Lee, and Byung-Chul Woo. "Design and Analysis of a Permanent Magnet Synchronous Motor Considering Axial Asymmetric Position of Rotor to Stator." Energies 12, no. 24 (2019): 4816. http://dx.doi.org/10.3390/en12244816.

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This paper presents the design and analysis of a permanent magnet synchronous motor (PMSM) considering the axial asymmetric PM overhang for a smart actuator (SA) application such as an isokinetic exercise machine. This structure helps take advantage of the motor space effectively and makes the system small in size and light in weight. However, two drawbacks related to the performance of motor occur when the axial asymmetric PM overhang is used: (1) an axial attractive force (AAF) is created, which can produce motor noise and vibration; (2) the torque of motor is reduced compared with the symmetric PM overhang model. We used five steps to solve these problems. Firstly, the AAF according to the variation in axial position of the rotor to the stator was calculated and analyzed. Secondly, the torque was calculated under the same conditions to confirm that the system requirements were satisfied. The three-dimensional finite element analysis was used to determine the AAF and torque. Thirdly, the appropriate axial position of the rotor to the stator was suggested considering the analysis results and space inside the housing. Next, the commercial bearing type was chosen so that the total force acting on the bearing was below the bearing load limit to ensure motor stability. Finally, a prototype model was made and tested to confirm the accuracy of the analytical results. Through this study, by using the axial asymmetric PM overhang, the total length of SA was reduced by 5mm and the performance of motor was guaranteed.
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Ni, Wei-Tou. "Searches for the Role of Spin and Polarization in Gravity: A Five-Year Update." International Journal of Modern Physics: Conference Series 40 (January 2016): 1660010. http://dx.doi.org/10.1142/s2010194516600107.

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Searches for the role of spin in gravitation dated before the firm establishment of the electron spin in 1925. Since mass and spin, or helicity in the case of zero mass, are the Casimir invariants of the Poincaré group and mass participates in universal gravitation, these searches are natural steps to pursue. In this update, we report on the progress on this topic in the last five years after our last review. We begin with how is Lorentz/Poincaré group in local physics arisen from spacetime structure as seen by photon and matter through experiments/observations. The cosmic verification of the Galileo Equivalence Principle for photons/electromagnetic wave packets (Universality of Propagation in spacetime independent of photon energy and polarization, i.e. nonbirefringence) constrains the spacetime constitutive tensor to high precision to a core metric form with an axion degree and a dilaton degree of freedom. Hughes-Drever-type experiments then constrain this core metric to agree with the matter metric. Thus comes the metric with axion and dilation. In local physics this metric gives the Lorentz/Poincaré covariance. Constraints on axion and dilaton from polarized/unpolarized laboratory/astrophysical/cosmic experiments/observations are presented. In the end, we review the theoretical progress on the issue of gyrogravitational ratio for fundamental particles and the experimental progress on the measurements of possible long range/intermediate range spin-spin, spin-monopole and spin-cosmos interactions.
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Salma, Nurul Fathia. "Exploring Critical Discourse Analysis’s Renowned Studies: Seeking for Aims and Approaches." REiLA: Journal of Research and Innovation in Language 1, no. 1 (2019): 17–22. http://dx.doi.org/10.31849/reila.v1i1.2769.

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This paper is trying hard to linked all its resources the study conducted by renowned researchers which discuss about Introduction to Critical Discourse Analysis (CDA) where includes the definitions, the manner to do Critical Discourse analysis guided by the established framework. Based on the theories of Michel Foucault, “discourse analysis is focusing on power of relationships in society as expressed by means of language and practices” this study puts its stand of viewpoint. Besides, there are several renowned studies to help understand the principle e.g.,, aims and approaches of CDA. This study believed and stick to the Foucauldian discourse analysis look at how the figures used language to propose their power dominance, and request obedience and honor from those subordinate to them which the are five steps are recommended based on the identification of rules in using "Foucauldian discourse analysis". However this study also still a high admiration to others scholars aims and approaches used e.g,. van Dijk, Wodak and Faiclough.
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Vemuru, Krishnamurthy V. "Implementation of the Canny Edge Detector Using a Spiking Neural Network." Future Internet 14, no. 12 (2022): 371. http://dx.doi.org/10.3390/fi14120371.

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Edge detectors are widely used in computer vision applications to locate sharp intensity changes and find object boundaries in an image. The Canny edge detector is the most popular edge detector, and it uses a multi-step process, including the first step of noise reduction using a Gaussian kernel and a final step to remove the weak edges by the hysteresis threshold. In this work, a spike-based computing algorithm is presented as a neuromorphic analogue of the Canny edge detector, where the five steps of the conventional algorithm are processed using spikes. A spiking neural network layer consisting of a simplified version of a conductance-based Hodgkin–Huxley neuron as a building block is used to calculate the gradients. The effectiveness of the spiking neural-network-based algorithm is demonstrated on a variety of images, showing its successful adaptation of the principle of the Canny edge detector. These results demonstrate that the proposed algorithm performs as a complete spike domain implementation of the Canny edge detector.
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Huldiansyah, Denny, Tiara Rukmaya Dewi, and Nadia Almira Jordan. "Rancangan Lansekap Gedung Kuliah E Kampus Institut Teknologi Kalimantan Sebagai Ruang Multi Fungsi." JAUR (JOURNAL OF ARCHITECTURE AND URBANISM RESEARCH) 6, no. 1 (2022): 20–31. http://dx.doi.org/10.31289/jaur.v6i1.6215.

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The presence of open spaces in the spatial order of the campus can encourage students to engage in outdoor activities aimed at improving their quality of life and academic performance. Providing an integrated, open campus space is the key to creating a unique, dynamic, and aesthetic campus. During development, Institut Teknologi Kalimantan (ITK) continues to develop the infrastructure to support all lecture events, one of which is an open space configuration for College Building E. The landscape design process for this college building is in progress. It consists of five steps consisting of (1) problem identification; (2) data collection; (3) data analysis; (4) formulation of concepts; and (5) Design. The landscape design concept of College Building E conceptually applies the principle of multifunctional space as seen in the design of public green open spaces that combine the functions of public and green spaces. The coexistence of public and green spaces creates harmony in the design of educational, recreational, interactive, aesthetic, and dynamic open spaces.
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Ismail and Siti Ainim Liusti. "Kesantunan Mengkritik Bossman Mardigu Di Acara Youtube." Persona: Kajian Bahasa dan Sastra 2, no. 2 (2023): 275–86. http://dx.doi.org/10.24036/jpers.v2i2.146.

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This study aims to describe (1) the politeness principles used by Bossman Mardigu on the YouTube show, (2) the language politeness strategies used by Bossman Mandigu. The research data are in the form of words, phrases, clauses, and sentences related to politeness criticizing Bossman Mardigu on the YouTube program. The data collection techniques used in this study are as follows: (1) Download videos of the Bossman Mardigu podcast via YouTube. (2) listening to Bossman Mardigu's podcast and transcribing the data into written form, (3) inventorying the data into an inventory format. The validation technique in this study uses a triangulation technique. Furthermore, data analysis in this study was carried out with the following work steps: (1) grouping data in the form of polite speeches criticizing Bossman Mardigu on YouTube; (2) analyzing data that has been grouped through the data classification stage; (3) interpreting the data found; and (4) summarizing the data and writing reports or analyses that have been carried out. There are two findings in this research. First found as many as six violations of the principle of politeness. Secondly, there were five speech strategies used by Bossman Mardigu. Based on the research findings, it can be concluded that Bossman Mardigu violates the principle of politeness more when criticizing, or can be said to be impolite.
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Nyabuga, Douglas Omwenga, Jinling Song, Guohua Liu, and Michael Adjeisah. "A 3D-2D Convolutional Neural Network and Transfer Learning for Hyperspectral Image Classification." Computational Intelligence and Neuroscience 2021 (August 21, 2021): 1–19. http://dx.doi.org/10.1155/2021/1759111.

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As one of the fast evolution of remote sensing and spectral imagery techniques, hyperspectral image (HSI) classification has attracted considerable attention in various fields, including land survey, resource monitoring, and among others. Nonetheless, due to a lack of distinctiveness in the hyperspectral pixels of separate classes, there is a recurrent inseparability obstacle in the primary space. Additionally, an open challenge stems from examining efficient techniques that can speedily classify and interpret the spectral-spatial data bands within a more precise computational time. Hence, in this work, we propose a 3D-2D convolutional neural network and transfer learning model where the early layers of the model exploit 3D convolutions to modeling spectral-spatial information. On top of it are 2D convolutional layers to handle semantic abstraction mainly. Toward simplicity and a highly modularized network for image classification, we leverage the ResNeXt-50 block for our model. Furthermore, improving the separability among classes and balance of the interclass and intraclass criteria, we engaged principal component analysis (PCA) for the best orthogonal vectors for representing information from HSIs before feeding to the network. The experimental result shows that our model can efficiently improve the hyperspectral imagery classification, including an instantaneous representation of the spectral-spatial information. Our model evaluation on five publicly available hyperspectral datasets, Indian Pines (IP), Pavia University Scene (PU), Salinas Scene (SA), Botswana (BS), and Kennedy Space Center (KSC), was performed with a high classification accuracy of 99.85%, 99.98%, 100%, 99.82%, and 99.71%, respectively. Quantitative results demonstrated that it outperformed several state-of-the-arts (SOTA), deep neural network-based approaches, and standard classifiers. Thus, it has provided more insight into hyperspectral image classification.
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Joshi, Pinki Mayankkumar, and Urmi Kalrav Patel. "Performance evaluation of routine analytes using six sigma principle in a stand-alone clinical laboratory." International Journal of Clinical Biochemistry and Research 9, no. 2 (2022): 127–34. http://dx.doi.org/10.18231/j.ijcbr.2022.026.

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Sigma metrics of analytes based on data generated from IQC and EQAS is a reliable way of assessing and improving quality performance in the clinical laboratory. This study was undertaken to assess the sigma metrics of analytes used on a routine basis on a VITROS integrated analyser. Steps to improve quality based on the IQC and EQAS results was done monthly, based on QGI scores. The average sigma metrics at the end of year was compared with subsequent year. Data is presented for this comparison for four consecutive years between April 2017 to March 2021. 75% of analytes (12 out of 16) performed ≥ six sigma level on the current analyser in 2020-21, while 25% to 57% of routine analytes performed ≥ six sigma across published studies cited. Tests used for diagnostics which have high severity risk index such as Sodium, Creatinine, Glucose, Calcium and Uric Acid, all except Sodium had average sigma scores of more than six in VITROS 5600 analyzer used in this laboratory. On comparing performance of these important analytes across studies cited here, it was noticed that creatinine was a differentiator in this study which consistently performed at &amp;#62;6 sigma while in five of six studies cited the sigma score is less than six. In the context of the revised CLIA guidelines in 2019 wherein TE(a) for ten routine analytes have been reduced, it was noticed that with the lowering of TE(a) for many of these analytes, except uric acid, Triglycerides and AST, the performance shifted from &amp;#62; six sigma to a sigma lower than six.
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Jum’a, Luay, and Muath Esam Basheer. "Analysis of Warehouse Value-Added Services Using Pareto as a Quality Tool: A Case Study of Third-Party Logistics Service Provider." Administrative Sciences 13, no. 2 (2023): 51. http://dx.doi.org/10.3390/admsci13020051.

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The study aims to analyse warehouse value-added services (VAS) data for a third-party logistics (3PL) service provider, which leads to identifying service improvements and cost-cutting opportunities in performing VAS for clients using Pareto analysis as a quality tool. Using a case study approach, qualitative and quantitative data were collected from a leading 3PL firm in Belgium. The approach is conducted by applying major steps of Pareto analysis. Two pharmaceutical products were analysed according to medical general classification, namely narcotic analgesics (NA) and ophthalmic antihistamines and decongestants (OAD). The results showed that the Pareto principle is proven in the NA—ticketing case, and five activities consumed 83.3 percent of the total time of VAS operations. Furthermore, in the OAD—display case, the Pareto principle is proven and six activities were validated as they accounted for 81.26 percent of the total time of primary VAS operations. The study recommended a solution to each of the four causes of delay, including lack of training/best practices, inefficient space utilization, lack of automation, and lack of cohesiveness and planning. Despite the recognized importance of avoiding warehouse operation inefficiencies, the literature lacks studies applied to practice, and few contributions exist regarding analysing 3PL service providers’ warehousing VAS operations data. This study identified all VAS activities for temperature-controlled pharmaceutical products. Moreover, the study proposes a warehouse operations improvement framework for non-automated 3PL warehouses and guides managers through Pareto analysis to cut costs and improve service level.
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Goldoni, Marco, and Christopher McCorkindale. "Why We (Still) Need a Revolution." German Law Journal 14, no. 12 (2013): 2197–227. http://dx.doi.org/10.1017/s207183220000273x.

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This paper posits a (very British!) call to arms, and does so in five steps. In part A, we address the need for constitutional fictions by which the many surrender political power to the few, in the name of stability, order and security. In part B, however, we will show that conflict is both a necessary and a core principle of political constitutionalism—that it is the latent possibility of conflict, the (re)awkening of the many where the few abuse that power, that acts as the final check on government. In part C, we trace the steps by which recent re-interpretations of the work of J.A.G. Griffith, with a focus on the work of Tomkins and Bellamy, have reduced politics to its parliamentary form, thereby closing—rather than “enlarging”—the “areas for argument and discussion”—a narrow view of the constitution to which, admittedly, Griffith himself might have subscribed. In part D, we will assess the limits of such a narrow reading of the political and argue that a more dynamic and reflexive approach is needed if we are to remain in—or recover to—rude constitutional health. Finally, in part E, we will use the political and constitutional background to the devolution of legislative and executive power to Scotland in order to demonstrate the power of political conflict, in extraordinary moments, to expose, break down and create new constitutional fictions.
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Ab-Samat, Hasnida, and Shahrul Kamaruddin. "Development of opportunistic maintenance policy towards optimal maintenance system (OPTOMS) model." Journal of Quality in Maintenance Engineering 26, no. 1 (2019): 129–65. http://dx.doi.org/10.1108/jqme-07-2018-0057.

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Purpose Opportunistic maintenance (OM) policy is a prospective maintenance approach that instigates for a more effective and optimized system. The purpose of this paper is to provide the steps and methods used in model development processes for the application of the OM policy. Design/methodology/approach Dubbed as opportunistic principle toward optimal maintenance system (OPTOMS) for OM policy toward optimal maintenance system, the model is devised as a decision support system model and contains five phases. The motivation and focus of the model resolve around the need for a practical framework or model of maintenance policy for the application in an industry. In this paper, the OPTOMS model was verified and validated to ensure that the model is applicable in the industry and robust as a support system in decision making for the optimal maintenance system. Findings From the verification steps conducted in a case study company, it was found that the developed model incorporated simple but practical tools like check sheet, failure mode and effect analysis (FMEA), control chart that has been commonly used in the industry. Practical implications This paper provides the general explanations of the developed model and tools used for each phase in implementing OM to achieve an optimal maintenance system. Based on a case study conducted in a semiconductor company, the OPTOMS model can align and prepare the company in increasing machine reliability by reducing machine downtime. Originality/value The novelty of this paper is based on the in-depth discussion of all phases and steps in the model that emphasize on how the model will become practical theories in conducting an OM policy in a company. The proposed methods and tools for data collection and analysis are practical and commonly used in the industry. The framework is designed for practical application in the industry. The users would be from the Maintenance and Production Department.
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Ghimire, Srijana, and Xiang-Sheng Wang. "Traveling waves in cooperative predation: relaxation of sublinearity." Mathematics in Applied Sciences and Engineering 2, no. 1 (2021): 22–31. http://dx.doi.org/10.5206/mase/13393.

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In this paper, we investigate traveling wave solutions of a diffusive predator-prey model which takes into consideration hunting cooperation. Sublinearity condition is violated for the function of cooperative predation. When the basic reproduction number for the diffusion-free model is greater than one, we find a critical wave speed below which no positive traveling wave solution shall exist. On the other hand, if the wave speed exceeds this critical value, we prove the existence of a positive traveling wave solution connecting the predator-free equilibrium to the unique positive equilibrium under a technical assumption of weak cooperative predation. The key idea of the proof contains two major steps: (i) we construct a suitable pentahedron and find inside it a trajectory connecting the predator-free equilibrium; and (ii) we construct a suitable Lyapunov function and use LaSalle invariance principle to prove that the trajectory also connects the positive equilibrium. In the end of this paper, we propose five open problems related to traveling wave solutions in cooperative predation.
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Basedow, Jürgen, Jan Dietze, Stefan Griller, et al. "European integration: Quo vadis? A critical commentary on the PSPP judgment of the German Federal Constitutional Court of May 5, 2020." International Journal of Constitutional Law 19, no. 1 (2021): 188–207. http://dx.doi.org/10.1093/icon/moab017.

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Abstract In its judgment of May 5, 2020, the Second Senate of the German Constitutional Court qualified for the first time a judgment of the Court of Justice of the European Union (CJEU)—C-493/17 Weiss—as “arbitrary from an objective perspective” and declared the underlying European Central Bank (ECB) decisions regarding the Public Sector Purchase Programme (PSPP) to be ultra vires. It requested the German Government and the German Parliament to take steps against the PSPP in its current form and to ensure that the ECB conducts a proportionality assessment of its PSPP. The judgment also prohibits the German Central Bank from participating, after a grace period of three months, in the implementation and execution of the ECB decisions at issue, unless the ECB assesses and substantiates that the measures provided for in its decisions satisfy the principle of proportionality. The present article, which was written by academics, lawyers, and civil servants from five countries, casts a critical eye on the judgment of the German Constitutional Court. It identifies significant shortcomings from both a German constitutional and a European Union perspective.
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Nie, Cong. "Study on Reasonable Injection-Production Parameters of Water-Flooding Reservoir: A Case Study of Daqing Oilfield." E3S Web of Conferences 329 (2021): 01065. http://dx.doi.org/10.1051/e3sconf/202132901065.

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This paper, by conducting comprehensive analysis on water-flooding reservoir, intensively studied and discussed the characteristics of geological development, determined the evaluation indexes of development effect, carried out research from five steps, the first is the introduction part, it conducted indepth study and discussion from research background, research significance, literature review, and research methods four aspects. The second outlined the related theory from the optimization principle and mechanism of injection-production parameters, and the distribution mechanism of remaining oil two aspects. The third analyzed the current situation of reasonable injection-production of water-flooding reservoirs in Daqing Oilfield from reservoir characteristics and reservoir deposition. The fourth evaluated the water-flooding development effect from combined water cut, changing conditions of production and predicted recovery ratio. The fifth intensively studied the reasonable injection-production parameters of water- flooding reservoirs in Daqing oilfield from design of separated layer water injection plan, maintaining level reservoir formation pressure, and reasonable plan of injection-production ratio and oil recovery rate three aspects, and provides theoretical guidance for later targeted excavation of water-flooding reservoirs.
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Ahn, Jina, Ji Eun Yu, Hanna Kim, et al. "AB5-Type Toxin as a Pentameric Scaffold in Recombinant Vaccines against the Japanese Encephalitis Virus." Toxins 15, no. 7 (2023): 425. http://dx.doi.org/10.3390/toxins15070425.

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Japanese encephalitis virus (JEV) is an enveloped icosahedral capsid virus with a prime neutralizing epitope present in E protein domain III (EDIII). E dimers are rearranged into a five-fold symmetry of icosahedrons. Cholera toxin B (CTB) and heat-labile enterotoxin B (LTB) of AB5-type toxin was used as the structural scaffold for emulating the pentameric axis of EDIII. We produced homo-pentameric EDIII through the genetic fusion of LTB or CTB in E. coli without recourse to additional refolding steps. Harnessing an RNA-mediated chaperone further enhanced the soluble expression and pentameric assembly of the chimeric antigen. The pentameric assembly was validated by size exclusion chromatography (SEC), non-reduced gel analysis, and a GM1 binding assay. CTB/LTB−EDIII chimeric antigen triggered high neutralizing antibodies against the JEV Nakayama strain after immunization in mice. Altogether, our proof-of-principle study creating a JEV-protective antigen via fusion with an AB5-type toxin as both a pentameric scaffold and a built-in adjuvant posits the bacterially produced recombinant chimeric antigen as a cost-effective alternative to conventional inactivated vaccines against JEV.
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David, Lydia K., Hermine Iita, and Matheus Namidi. "experience of nurses worked at the COVID-19 unit in intermediate Hospital Oshakati, Oshana Region, Namibia." International journal of health sciences 9, no. 1 (2025): 244–57. https://doi.org/10.53730/ijhs.v9n1.14927.

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The Coronavirus Disease (COVID-19) is the world’s most significant public health emergency. Nurses, essential members of the COVID-19 patient care team, are facing the majority of the problems brought on by the disease. To enhance the quality of care provided to COVID-19 patients, this study explored the experience of nurses who worked at the COVID-19 unit in Intermediate Hospital Oshakati, Oshana Region, Namibia. The study employed an exploratory and descriptive research design with a qualitative approach to the population of thirty-five nurses who worked at the COVID-19 unit in Intermediate Hospital Oshakati during the COVID-19 pandemic. Purposive sampling was used to select eight participants for data saturation. A semi-structured interview was used for data collection, and a tape recorder was utilized to capture the data. Thematic analysis was used for data analysis using the six steps proposed by Creswell (2014). Findings were presented in themes and subthemes for better comprehension. Ethical considerations were observed, such as approval, the principle of justice, confidentiality, privacy, beneficence, and non-maleficence.
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Paillin, Daniel, Johan Tupan, Jacobus Paillin, Wilma Latuny, and Victor Lawalata. "RISK ASSESSMENT AND RISK MITIGATION IN A SUSTAINABLE TUNA SUPPLY CHAIN." Acta logistica 9, no. 1 (2022): 51–61. http://dx.doi.org/10.22306/al.v9i1.270.

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This study aimed to conduct a risk assessment and minimize the risk of sustainable tuna supply chains in Ambon. The House of Risk (HOR) approach was utilized in this study to identify risk occurrences and risk agents in three aspects of sustainability. The study results identified 15 risk events and 26 risk agents consisting of four risk events and five risk agents on the environmental dimension, five risk events and eleven risk agents on the social dimension, six risk events, and ten risk agents on the economic dimension. The HOR phase I shows that the risk agent with the highest Aggregat Risk Priority (ARP) value is the lack of environmental management system standards (A4), and the risk agent with the lowest ARP value is inhumane treatment/harassment (A12). Based on the Pareto principle, 7 Risk Agents will be prioritized to be handled according to the highest ARP value, such as lack of environmental management system standards (4170), lack of quality control inspection (3790), lack of maintenance management (3346), lack of quality control from suppliers (3000), lack of enthusiasm for work (2984), decreased level of discipline (2832). The internal communication system of the company is poor (2538). Furthermore, 15 mitigating techniques are proposed. Twelve mitigation technique steps are chosen from 15 recommended solutions to prevent the causes of risk based on the effectiveness to difficulty (ETD) value from HOR phase II.
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46

Listyani, Listyani. "Academic Writing Students’ Affective Reactions towards Joint Reconstruction Phase of Reading to Learn." Celt: A Journal of Culture, English Language Teaching & Literature 17, no. 2 (2017): 251. http://dx.doi.org/10.24167/celt.v17i2.1206.

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Academic Writing can be considered a difficult writing course which can make students exhausted and even frustrated. The principle of the more you read, the better you write may be applicable to this course. One way to make students write better is by asking them to read more and giving them some model texts to learn. Asking them to work collaboratively with their peer students can also help. The series of steps are included in Reading to Learn (R2L) teaching method that I developed for my Academic Writing Class in Semester II/ 2015-2016 Academic Year. This study mainly tried to describe how introverted and extroverted students of an Academic Writing class of the Faculty of Language and Literature, Universitas Kristen Satya Wacana Salatiga, Indonesia, reacted to the phase when they were supposed to work with their peers to produce an outline and an essay. Among other 21 students in the class, five who were found to be introverted, and five other extroverted, became the respondents of the study. They were selected based on questionnaires they filled in the previous semester. Data were mainly derived from journals that they submitted every time they passed a step, and also from observation done through video recording during the whole semester. Findings show that the ten students showed different affective reactions towards collaborative writing
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47

Edison, Edison, Abu Anwar, and Elbina Mamla Saidah. "KNOWLEDGE ISLAMIZATION MODEL OF ISMA'IL RAJI AL FARUQI'S PERSPECTIVES FACING THE EDUCATION CHALLENGES IN THE 21st CENTURY." Lentera Pendidikan : Jurnal Ilmu Tarbiyah dan Keguruan 25, no. 2 (2022): 296–310. http://dx.doi.org/10.24252/lp.2022v25n2i9.

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This study aims to compile the work steps of the Islamization of science based on the Islamization model formulated by Isma'il Raji Al Faruqi. This qualitative approach research uses literature study method. This study identifies unhealthy symptoms in the aspects of scientific jurisprudence among Muslims who have not shown symptoms of recovery even in the 21st century. The results of the analysis then prompted the prioritization of the work plan for the Islamization of science in accordance with the ideas of Isma'il Raji Al Faruqi. The work plan begins with strengthening the five principle of unity and focuses on Islamization with a scientific integration model in the five fields of science, namely religious studies, educational management, research methodology, politics, and economics.&#x0D; Abstrak: &#x0D; Penelitian ini bertujuan menyusun langkah-langkah kerja Islamisasi ilmu pengetahuan berdasarkan model Islamisasi yang dirumuskan oleh Isma’il Raji Al Faruqi. Penelitian dengan pendekatan kualitatif ini menggunakan metode studi literatur. Penelitian ini mengidentifikasi gejala tidak sehat dalam aspek fikrah keilmuan di kalangan umat Islam yang belum menunjukkan gejala kepulihan bahkan hingga abad 21 ini. Hasil analisis tersebut kemudian mendorong penetapan prioritas rencana kerja Islamisasi ilmu pengetahuan sesuai dengan gagasan Isma’il Raji Al Faruqi. Rencana kerja tersebut dimulai dengan penguatan prinsip panca kesatuan dan fokus melakukan Islamisasi dengan model integrasi keilmuan pada lima bidang ilmu pengetahuan yakni studi agama, manajemen pendidikan, metodologi penelitian, politik, dan ekonomi.
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Si, Binghui, Feng Liu, and Yanxia Li. "Metamodel-Based Hyperparameter Optimization of Optimization Algorithms in Building Energy Optimization." Buildings 13, no. 1 (2023): 167. http://dx.doi.org/10.3390/buildings13010167.

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Building energy optimization (BEO) is a promising technique to achieve energy efficient designs. The efficacy of optimization algorithms is imperative for the BEO technique and is significantly dependent on the algorithm hyperparameters. Currently, studies focusing on algorithm hyperparameters are scarce, and common agreement on how to set their values, especially for BEO problems, is still lacking. This study proposes a metamodel-based methodology for hyperparameter optimization of optimization algorithms applied in BEO. The aim is to maximize the algorithmic efficacy and avoid the failure of the BEO technique because of improper algorithm hyperparameter settings. The method consists of three consecutive steps: constructing the specific BEO problem, developing an ANN-trained metamodel of the problem, and optimizing algorithm hyperparameters with nondominated sorting genetic algorithm II (NSGA-II). To verify the validity, 15 benchmark BEO problems with different properties, i.e., five building models and three design variable categories, were constructed for numerical experiments. For each problem, the hyperparameters of four commonly used algorithms, i.e., the genetic algorithm (GA), the particle swarm optimization (PSO) algorithm, simulated annealing (SA), and the multi-objective genetic algorithm (MOGA), were optimized. Results demonstrated that the MOGA benefited the most from hyperparameter optimization in terms of the quality of the obtained optimum, while PSO benefited the most in terms of the computing time.
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Ma, Ying, Weihong Xiang, Sheng Lu, Hanjie Hu, and Xianjun Zeng. "A dynamic weaving simulator for filament-level 3D woven fabric modelling." Journal of Industrial Textiles 52 (August 2022): 152808372211395. http://dx.doi.org/10.1177/15280837221139554.

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A dynamic textile weaving simulator is established to connect weaving actions to fabric patterns and microstructures. It utilizes the Digital Element Approach (DEA) under the framework of the software package Digital Fabric and Composite Analyser (DFCA). The key components of a Jacquard loom are explicitly modelled utilising the ‘hole/no hole’ principle. Yarn interlacing motion is guided by weaving matrix specified by steps. Shedding, weft insertion, beat-up, and take-up actions are modelled and explained. The inter-fibre contact force, fibre forces (tensile, shear, and bending), and boundary conditions in the weft direction are considered. The weaving process of five cells in the warp direction of a 10-layer 3D orthogonal woven fabric is simulated at the filament level to derive for its microstructure. The results show that the fabric microstructure continues to change after being woven, and the thickness and length of each individual cell decrease with further weaving steps. The microstructures of newly woven cells converge after the weaving of two further cells in the lengthwise direction. The microstructure of the second cell closely matches that of an actual weaved fabric, as evaluated by microscopy images. Penetration occurs between adjacent weft yarns in the same column, which fundamentally changes their microstructure, composition, and material properties. Parametric studies show that the ratio of binder to warp yarn tension determines the fabric thickness. Increases in the take-up length and binder yarn tension lead to a decrease and increase in the reed tension, respectively. This work provides valuable insights into fabric design and manufacture instruction.
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Vorzhakova, Yuliia, and Kateryna Boiarynova. "The Application of Digitalization in Enterprises on the Basis of Multiple Criteria Selection Design." Central European Management Journal 28, no. 3 (2020): 127–48. http://dx.doi.org/10.7206/cemj.2658-0845.29.

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Purpose: The increasing role of digitalization in the operation of enterprises actualizes the implementation of the basic methods of proper digitalization processes. The selection of an appropriate method to introduce digitalization is crucial, as it affects the optimization level of the business processes. Methodology: Specific multicriteria selection method includes five steps to identify these approaches, considering the relative error for each approach, as it affects the outcome with the performance indicator of business process digitalization. The strongest criterion value is used to identify the optimal approach. The evaluation of the methods showed that the performance of the logistic, administrative, and innovative methods is not worse than the Pareto principle. Findings: Introducing digitalization in the administrative method has the biggest impact. The chosen method showed that Human Resources processes require modification to reduce costs. A mechanism to digitalize the personnel management processes using artificial intelligence was developed. Implications: The results of multivariate multicriteria analysis show that the implementation of artificial intelligence minimizes human factors and optimizes time and costs. Originality: The main contribution is the development of the method for the selection of an appropriate digitalization approach, which encompasses an implementation mechanism that can be adapted to enterprises’ needs.
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