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Journal articles on the topic 'The synthetic index of costs'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Bollen, Nicolas P. B., and Jeffrey A. Busse. "Tick Size and Institutional Trading Costs: Evidence from Mutual Funds." Journal of Financial and Quantitative Analysis 41, no. 4 (2006): 915–37. http://dx.doi.org/10.1017/s0022109000002696.

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AbstractThis paper measures changes in mutual fund trading costs following two reductions in the tick size of U.S. equity markets: the switch from eighths to sixteenths and the subsequent switch to decimals. We estimate trading costs by comparing a mutual fund's daily returns to the daily returns of a synthetic benchmark portfolio that matches the fund's holdings but has zero trading costs by construction. We find that the average change in trading costs of actively managed funds was positive following both reductions in tick size with a larger and statistically significant increase following

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Leszczyńska, Agnieszka. "Ceny usług związanych z użytkowaniem mieszkań przez właścicieli we wskaźniku cen towarów i usług konsumpcyjnych." Wiadomości Statystyczne. The Polish Statistician 2011, no. 3 (2011): 1–10. http://dx.doi.org/10.59139/ws.2011.03.1.

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The Consumer Price Index (CPI) is a main synthetic measure of changes in living expenses of an average household. In order to fulfill this role, the structure of the index should correspond with the actual consumption pattern of households. The housing service consumed by the homeowners (owner occupied housing – OOH), a very important component of consumption, is currently omitted in the Polish CPI. The article presents a summary of the ongoing discussion on including the housing service costs in the CPI. Some theoretical arguments are followed by the description of the most frequently used wa

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Dore, R. K., J. Antonova, L. Chang, M. Gorritz, X. Wang, and M. C. Genovese. "THU0555 HEALTHCARE COSTS IN PATIENTS WITH RHEUMATOID ARTHRITIS SWITCHING FROM THEIR FIRST CONVENTIONAL SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUG TO ANOTHER DISEASE-MODIFYING ANTIRHEUMATIC DRUG REGIMEN." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 518–19. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2017.

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Background:EULAR and ACR guidelines recommend a treat-to-target approach for rheumatoid arthritis (RA). For patients failing their first conventional synthetic disease-modifying antirheumatic drug (csDMARD), EULAR recommends switching to or adding another DMARD. Understanding treatment patterns, durability, and healthcare costs associated with treatments initiated after first csDMARD can help optimize treatment for these patients.Objectives:To describe real-world healthcare costs among patients with RA who failed their first csDMARD.Methods:The study included adults with ≥2 RA claims ≥30 days

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CADOT, OLIVIER, CELINE CARRERE, JAIME DE MELO, and BOLORMAA TUMURCHUDUR. "Product-specific rules of origin in EU and US preferential trading arrangements: an assessment." World Trade Review 5, no. 2 (2006): 199–224. http://dx.doi.org/10.1017/s1474745606002758.

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Building on earlier work by Estevadeordal (2000), we construct a synthetic index (R-index) intending to capture the restrictiveness of rules of origin in preferential trading agreements. The R-index is applied to NAFTA and the Single List of the EU's PANEURO system covering all of the EU's preferential trade agreements. The R-index highlights how a common set of rules of origin can affect countries differently depending on their export structures, and how their complexity varies across sectors. Having controlled for the extent of tariff preference at the tariff-line level, the R-index contribu

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Sikora, Adam Tomasz, and Joanna Ukalska. "The main costs of natural disasters in the Forest District of Węgierska Górka." Forest Research Papers 75 (3) (September 1, 2014): 263–75. https://doi.org/10.2478/frp-2014-0026.

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The aim of the study was to determine the impact of increased forest management due to natural disasters on particular core unit costs. We analysed the direct costs for the Forest District of Węgierska Górka in the years 2004–2010 based on information from the State Forests lnformation System (SFIS) database compared with selected forest districts within the Regional Directorate of State Forests in Cracow (RDSF). The forest districts were divided into two groups with two and six forest districts and confidence intervals around the mean were determined and the significance of linea

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Alves, Lucas da Silva, Cinthia Elen Cardoso Caitano, Samuel Ferrari, et al. "Application of Spent Sun Mushroom Substrate in Substitution of Synthetic Fertilizers at Maize Topdressing." Agronomy 12, no. 11 (2022): 2884. http://dx.doi.org/10.3390/agronomy12112884.

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Synthetic fertilization can increase maize yields, but also cause environmental impacts, as well as increasing production costs and food security risks. Sun mushroom (Agaricus subrufescens) is an important Brazilian fungus used to generate large amounts of spent mushroom substrate. This residue can be used for maize fertilization, but little is known about its ideal application rates to reduce maize dependence on synthetic fertilizers. Therefore, this study aimed to evaluate the agronomic performance of a maize crop under different combinations of synthetic fertilizers and two different spent

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Mihailova-Toneva, Mariya, and Tanya Ivanova. "Influence of factors on change in gross profit and level of profitability in milk production from Bulgarian Dairy Synthetic Population." Bulgarian Journal of Animal Husbandry 60, no. 5 (2023): 57–65. http://dx.doi.org/10.61308/mywg7582.

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The purpose of the present study is an analysis of the influence of various factors on the indicators of gross profit and level of profitability in the production of milk from sheep of the Bulgarian Dairy Synthetic Population breed for a period of 3 years. Data from the accounting department of Institute of Animal Sciences -Kostinbrod were used. The indicators were analyzed: average yield (l), average selling price of 1 l of milk, cost of variable production costs for 1 l of milk, gross income from milk, gross profit, level of profitability of variable costs. The index factor analysis (method

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José Herrera, Juan, Valeria Rivera, and Alexander Obando. "Productive behavior of piglets (Sus scrofa domesticus) fed concentrates with an inclusion of six natural flavorings and one commercial synthetic flavoring." Agroindustrial Science 13, no. 3 (2024): 143–48. http://dx.doi.org/10.17268/agroind.sci.2023.03.04.

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Natural additives can provide positive characteristics that help make animal feed more palatable, thereby increasing feed intake and improving productivity. In this study, 260 piglets from 14 to 56 days of age were monitored, with an initial weight of 4.34 ± 0.75 kilograms. There were 6 treatments with natural flavorings with pro-nutrients, plus 1 treatment with a commercial product, and 1 control without flavorings. The average daily feed consumption per piglet was between 408 and 525 g, the average final weights between 19.90 and 26.30 kg, the average daily weight gains between 0.367 and 0.5

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Boyce, Eric G., Edward L. Rogan, Deepti Vyas, Neel Prasad, and Yvonne Mai. "Sarilumab: Review of a Second IL-6 Receptor Antagonist Indicated for the Treatment of Rheumatoid Arthritis." Annals of Pharmacotherapy 52, no. 8 (2018): 780–91. http://dx.doi.org/10.1177/1060028018761599.

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Major Objectives: To review the efficacy, safety, and economics of sarilumab, an interleukin-6 (IL-6) receptor antagonist, in the treatment of rheumatoid arthritis (RA). Data Sources: PubMed (1966 to January 2018), Clinicaltrials.gov (January 2018), and Scopus (1970 to January 2018) were searched using sarilumab, Kevzara, REGN88, and SAR153191. Study Selection and Data Extraction: Human studies published in peer-reviewed publications in English were the primary sources for efficacy and safety. Data Synthesis: Data from randomized, double-blind, controlled, published clinical studies weeks demo

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Staartjes, Victor E., Peter R. Seevinck, W. Peter Vandertop, Marijn van Stralen, and Marc L. Schröder. "Magnetic resonance imaging–based synthetic computed tomography of the lumbar spine for surgical planning: a clinical proof-of-concept." Neurosurgical Focus 50, no. 1 (2021): E13. http://dx.doi.org/10.3171/2020.10.focus20801.

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OBJECTIVEComputed tomography scanning of the lumbar spine incurs a radiation dose ranging from 3.5 mSv to 19.5 mSv as well as relevant costs and is commonly necessary for spinal neuronavigation. Mitigation of the need for treatment-planning CT scans in the presence of MRI facilitated by MRI-based synthetic CT (sCT) would revolutionize navigated lumbar spine surgery. The authors aim to demonstrate, as a proof of concept, the capability of deep learning–based generation of sCT scans from MRI of the lumbar spine in 3 cases and to evaluate the potential of sCT for surgical planning.METHODSSyntheti

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Woo, Hyuna, Hyeonjin Choi, Minyoung Kim, and Seong Jin Noh. "Physics-Guided Deep Learning for Spatiotemporal Evolution of Urban Pluvial Flooding." Water 17, no. 8 (2025): 1239. https://doi.org/10.3390/w17081239.

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Climate change and rapid urbanization have increased the risk of urban flooding, making timely and accurate flood prediction crucial for disaster response. However, conventional physics-based models are limited in real-time applications due to their high computational costs. Recent advances in deep learning have enabled the development of efficient surrogate models that capture complex nonlinear relationships in hydrological processes. This study presents a deep learning-based surrogate model designed to efficiently reproduce the spatiotemporal evolution of urban pluvial flooding using data fr

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Silva, Grazielle, Juliana Alvares, Eli Iola Andrade, et al. "VP53 Cost-Utility Analysis: Adalimumab Verus Etanercept in Rheumatoid Arthritis – Brazil." International Journal of Technology Assessment in Health Care 33, S1 (2017): 171–72. http://dx.doi.org/10.1017/s0266462317003336.

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INTRODUCTION:Rheumatoid arthritis (RA) is an inflammatory, autoimmune disease of unknown etiology that usually results in joint lesions and physical incapacitation. RA treatment includes disease-modifying antirheumatic drugs (DMARD), synthetic (sDMARD) and/or biologics (bDMARD). In this study we carried out a cost-utility analysis comparing Adalimumab (ADA) versus Etanercept (ETA), with or without synthetic DMARDs (± sDMARD).METHODS:Effectiveness measures used were the Clinical Disease Activity Index (CDAI) and Quality-Adjusted Life Years (QALY) obtained from an open prospective cohort study w

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Golovina, N. V., and M. V. Matveeva. "Improvement of pricing in the construction industry: Integrating information modeling technologies and transitioning regions to the resource index method." Journal «Izvestiya vuzov Investitsiyi Stroyitelstvo Nedvizhimost» 13, no. 3 (2023): 410–22. http://dx.doi.org/10.21285/2227-2917-2023-3-410-422.

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Ensuring accurate cost estimation for project implementation, while accounting for regional specifics, is a crucial task for pricing practices in the construction industry. To address this challenge, the transition from the base index method with cost item indexation to the resource index method for estimating project costs is planned in the 1st quarter of 2023. Additionally, starting from 2024, the mandatory use of information modeling technologies for project design will be implemented. This article examines the rationale behind implementing modifications in the pricing system, outlines the

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Pompilio, Giuseppe, and Davide Integlia. "Cost per responder for methotrexate versus other therapies in patients with moderate-to-severe plaque psoriasis in Italy." Global & Regional Health Technology Assessment 9 (November 10, 2022): 138–45. http://dx.doi.org/10.33393/grhta.2022.2474.

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Objective: Conventional synthetic disease modifying antirheumatic drugs (csDMARDs) were recommended in 2019 as first line therapy from Italian Medicines Agency (AIFA) for the treatment of moderate to severe psoriasis. Updated local guidelines recommended methotrexate (MTX) as the drug of first choice. Nevertheless, MTX is reported by AIFA to be underused. Since no study evaluated jointly the first-line efficacy and costs of the most widely used biologic drugs (adalimumab, etanercept, secukinumab and ustekinumab) and methotrexate in Italy, a cost per responder (CPR) analysis was performed. Meth

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Łada, Magdalena. "The competitive potential of the advanced technology sector." Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu 64, no. 7 (2020): 60–73. http://dx.doi.org/10.15611/pn.2020.7.05.

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The increasing use of advanced technologies by enterprises increases the importance of the advanced technology sector in national economies. For this reason, the purpose of the research presented in the study was to determine the competitive potential of the advanced technology sector on the intra-EU market in recent years. The evaluation was conducted using the labour productivity index, labour costs and the share of the number of high technology sector enterprises in the total number of enterprises in the EU sector. Based on partial indicators, a synthetic indicator was built which allowed f

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Akhter, Pervaiz, Zafar Iqbal Khan, Muhammad Iftikhar Hussain, et al. "Assessment of Heavy Metal Accumulation in Soil and Garlic Influenced by Waste-Derived Organic Amendments." Biology 11, no. 6 (2022): 850. http://dx.doi.org/10.3390/biology11060850.

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In South Asia, the high costs of synthetic fertilizers have imposed research on alternative nutrient inputs. We aimed to identify potential trace elements (PTE) present in some organic manure that might be a source of environmental pollutions and risk to public health following consumption. The study aims to evaluate how different organic waste (poultry waste, PW; press mud, PM; and farmyard manure, FYM) influences the heavy metal migration in soil, the accumulation in garlic, and their potential health risks. Organic waste caused a higher accumulation of certain metals (Zn, Cu, Fe, and Co), w

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Darmawan, Hendri, Mike Yuliana, Moch Zen Samsono Hadi, and Rahardhita Widyatra Sudibyo. "Fine-tuning GAN Models with Unpaired Aerial Images for RGB to NDVI Translation in Vegetation Index Estimation." International Journal on Advanced Science, Engineering and Information Technology 14, no. 5 (2024): 1654–62. http://dx.doi.org/10.18517/ijaseit.14.5.20063.

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Calculating the Normalized Difference Vegetation Index (NDVI) requires expensive multispectral cameras, posing challenges such as high costs and the need for technical expertise. This research aims to develop a method to transform RGB images obtained from Unmanned Aerial Vehicle (UAV) into NDVI images. Our proposed method leverages the CycleGAN model, an unsupervised image-to-image translation framework, to learn the intricate mapping between RGB values and NDVI. The model was trained on unpaired datasets of RGB and NDVI images, sourced from paddy fields located in Gresik and Yogyakarta, Indon

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Imani, Mahdi, Seyede Fatemeh Ghoreishi, Douglas Allaire, and Ulisses M. Braga-Neto. "MFBO-SSM: Multi-Fidelity Bayesian Optimization for Fast Inference in State-Space Models." Proceedings of the AAAI Conference on Artificial Intelligence 33 (July 17, 2019): 7858–65. http://dx.doi.org/10.1609/aaai.v33i01.33017858.

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Nonlinear state-space models are ubiquitous in modeling real-world dynamical systems. Sequential Monte Carlo (SMC) techniques, also known as particle methods, are a well-known class of parameter estimation methods for this general class of state-space models. Existing SMC-based techniques rely on excessive sampling of the parameter space, which makes their computation intractable for large systems or tall data sets. Bayesian optimization techniques have been used for fast inference in state-space models with intractable likelihoods. These techniques aim to find the maximum of the likelihood fu

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Balcerzak, Adam P., and Michał Bernard Pietrzak. "The Impact of the Efficiency of the Institutions on the Quality of Life in the European Union. Panel Data Evidence for the Years 2004–2010." Przegląd Statystyczny 62, no. 1 (2015): 71–92. http://dx.doi.org/10.5604/01.3001.0014.1705.

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The article concentrates on the problem of the effi ciency of the institutional system of the European Union countries in relation to the potential of the global knowledge-based economy (KBE) and its impact on quality of life. In order to defi ne the effi ciency of the institutional system, the authors refereed to the analytical structure of the new institutional economics, in particular, the transaction costs theory. On this basis, it is assumed that effective institutional factors are conducive to the reduction of transaction costs. To measure the effectiveness of the institutional system au

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Akram, Hesham, Hozayen A. Hozayen, Akmal Abdelfatah, and Farag Khodary. "Fiber Showdown: A Comparative Analysis of Glass vs. Polypropylene Fibers in Hot-Mix Asphalt Fracture Resistance." Buildings 14, no. 9 (2024): 2732. http://dx.doi.org/10.3390/buildings14092732.

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Cracks in asphalt mixtures compromise the structural integrity of roads, increase maintenance costs, and shorten pavement lifespan. These cracks allow for water infiltration, accelerating pavement deterioration and jeopardizing vehicle safety. This research aims to evaluate the impact of synthetic fibers, specifically glass fiber (GF) and polypropylene fiber (PPF), on the crack resistance of Hot-Mix Asphalt (HMA). An optimal asphalt binder content of 5% was used in all sample designs. Using the dry mixing technique, GFs and PPFs were incorporated into the HMA at dosages of 0.50%, 1.00%, and 1.

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Dore, R. K., J. Antonova, L. Chang, H. Huang, H. Kim, and M. C. Genovese. "SAT0066 BURDEN OF MALIGNANCY, VENOUS THROMBOEMBOLISM, ANEMIA, AND INFECTIONS IN PATIENTS WITH RHEUMATOID ARTHRITIS WHO SWITCHED FROM A FIRST CONVENTIONAL SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUG TO ANOTHER DISEASE-MODIFYING ANTIRHEUMATIC DRUG REGIMEN." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 966–67. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2141.

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Background:EULAR and ACR guidelines recommend a variety of treatment options for rheumatoid arthritis (RA) patients who failed a first conventional synthetic disease-modifying antirheumatic drug (csDMARD). The recent launches of Janus kinase inhibitors (JAKi) have stimulated interest in comorbidities such as malignancy, venous thromboembolism (VTE: deep vein thrombosis [DVT] or pulmonary embolism [PE]), anemia, and infections in patients with RA. Understanding the epidemiology of these conditions can help optimize treatment decisions within the treat-to-target approach following the first csDM

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De Petris, S., F. Sarvia, and E. Borgogno-Mondino. "SENTINEL-1 DATA TIME SERIES TO SUPPORT FOREST POLICE IN HARVESTINGS DETECTION." ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences V-3-2022 (May 17, 2022): 225–32. http://dx.doi.org/10.5194/isprs-annals-v-3-2022-225-2022.

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Abstract. Satellite remote sensing has long been used to monitor forest harvesting with accuracies appropriate for practical mapping across a wide range of forest types by using different sensors. Unfortunately, in Italy, most of the cuts take place in winter where the cloud cover is very high, making it impossible an early detection by optical data. In this framework, synthetic aperture radar (SAR) data such as Sentinel-1 (S1) allows a better land monitoring by penetrating cloud cover. In this work we tested some methods for time series breakpoint detection with the aim of mapping significant

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Li, Fangda, Zhenwei Guo, Xinpeng Pan, Jianxin Liu, Yanyi Wang, and Dawei Gao. "Deep Learning with Adaptive Attention for Seismic Velocity Inversion." Remote Sensing 14, no. 15 (2022): 3810. http://dx.doi.org/10.3390/rs14153810.

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The subsurface velocity model is crucial for high-resolution seismic imaging. Although full-waveform inversion (FWI) is a high-accuracy velocity inversion method, it inevitably suffers from challenging problems, including human interference, strong nonuniqueness, and high computing costs. As an efficient and accurate nonlinear algorithm, deep learning (DL) has been used to estimate velocity models. However, conventional DL is insufficient to characterize detailed structures and retrieve complex velocity models. To address the aforementioned problems, we propose a hybrid network (AG-ResUnet) in

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Valy, Assamo Esmael Amad, and José Aurélio Medeiros da Luz. "Size effects in itabirite jigging under high frequency." Ciência e Natura 47 (April 1, 2025): e85455. https://doi.org/10.5902/2179460x85455.

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Concentration jigs have been used in ore dressing since the Middle Ages. Contrary to other sorting methods, gravity separation is a unit operation that implies low operational and environmental costs. This work describes the effect of particle size on separation efficiency using synthetic quartz and hematite mixes, simulating itabirite ores. The technological parameters of a Harz-Denver type jig were studied as a rougher stage at bench scale, employing previously sized samples. The experiments were carried out using 12 size classes, under a stroke amplitude of 7.0 mm and various pulse frequenc

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Morello, Maria, Simone Mastrogiovanni, Fabio Falcione, et al. "Laboratory Diagnosis of Intrathecal Synthesis of Immunoglobulins: A Review about the Contribution of OCBs and K-index." International Journal of Molecular Sciences 25, no. 10 (2024): 5170. http://dx.doi.org/10.3390/ijms25105170.

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The diagnosis of MS relies on a combination of imaging, clinical examinations, and biological analyses, including blood and cerebrospinal fluid (CSF) assessments. G-Oligoclonal bands (OCBs) are considered a “gold standard” for MS diagnosis due to their high sensitivity and specificity. Recent advancements have involved the introduced of kappa free light chain (k-FLC) assay into cerebrospinal fluid (CSF) and serum (S), along with the albumin quotient, leading to the development of a novel biomarker known as the “K-index” or “k-FLC index”. The use of the K-index has been recommended to decrease

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Musteata, Vasile. "Updates in the management of non-Hodgkin’s lymphomas: epidemiological and socio-economical profile." Public Health, Economy and Management in Medicine, no. 2(89) (August 2021): 26–32. http://dx.doi.org/10.52556/2587-3873.2021.2(89).05.

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The increase of incidence in the working-age population, commonly late diagnosis and signifi cant levels of disability in non-Hodgkin’s lymphomas (NHL) may be considered as key topics of clinical hematooncology and public health management. An analytical study was performed – the narrative review of the literature under the form of a synthesis article. To achieve this goal, we searched by keywords for medical scientifi c publications in the database Google Search, PubMed, Z-library, NCIB, Medscape, Hinari. The incidence of NHL in Western countries is 14–19 new cases per 100000 of population (4

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Łukiewska, Katarzyna, and Małgorzata Juchniewicz. "Identification of the Relationships between Competitive Potential and Competitive Position of the Food Industry in the European Union." Sustainability 13, no. 8 (2021): 4160. http://dx.doi.org/10.3390/su13084160.

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The competitiveness of the food industry, which is among the most important areas in the Central European economy, is a significant and topical research area in economics. The sector is particularly important for long-term sustainable growth in Central European national economies. Its high competitiveness is an important stabiliser in an environment of global economic instability. This study aimed to assess the relationships between elements of competitive potential and the competitive position of the food industry in E.U. countries. The relationships between these categories were examined usi

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Gudiña, Eduardo J., Márcia R. Couto, Soraia P. Silva, et al. "Sustainable Exopolysaccharide Production by Rhizobium viscosum CECT908 Using Corn Steep Liquor and Sugarcane Molasses as Sole Substrates." Polymers 15, no. 1 (2022): 20. http://dx.doi.org/10.3390/polym15010020.

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Microbial exopolysaccharides (EPS) are promising alternatives to synthetic polymers in a variety of applications. Their high production costs, however, limit their use despite their outstanding properties. The use of low-cost substrates such as agro-industrial wastes in their production, can help to boost their market competitiveness. In this work, an alternative low-cost culture medium (CSLM) was developed for EPS production by Rhizobium viscosum CECT908, containing sugarcane molasses (60 g/L) and corn steep liquor (10 mL/L) as sole ingredients. This medium allowed the production of 6.1 ± 0.2

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Novais, Jean J., Raul R. Poppiel, Marilusa P. C. Lacerda, Manuel P. Oliveira, and José A. M. Demattê. "Spectral Mixture Modeling of an ASTER Bare Soil Synthetic Image Using a Representative Spectral Library to Map Soils in Central-Brazil." AgriEngineering 5, no. 1 (2023): 156–72. http://dx.doi.org/10.3390/agriengineering5010011.

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Pedological maps in suitable scales are scarce in most countries due to the high costs involved in soil surveying. Therefore, methods for surveying and mapping must be developed to overpass the cartographic material obtention. In this sense, this work aims at assessing a digital soil map (DSM) built by multispectral data extrapolation from a source area to a target area using the ASTER time series modeling technique. For that process, eight representative toposequences were established in two contiguous micro-watersheds, with a total of 42 soil profiles for analyses and classification. We foun

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Langer, Arielle L., Amey Rane, Louise Lombard та ін. "Association of Hemoglobin Levels with Healthcare Resource Utilization and Costs in Non-Transfusion-Dependent α- and β-Thalassemia: A Retrospective Observational Study Using Real-World Data". Blood 142, Supplement 1 (2023): 5244. http://dx.doi.org/10.1182/blood-2023-189236.

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Introduction: Alpha (α)- and beta (β)-thalassemia result from reduced synthesis of α- or β-globin, respectively, leading to ineffective erythropoiesis, chronic hemolytic anemia (HA), and related complications. Thalassemia can also be characterized phenotypically as transfusion-dependent thalassemia (TDT) or non-transfusion-dependent thalassemia (NTDT). Decrease in hemoglobin (Hb) has been linked to increased risk of comorbidities and number of comorbidities in NTD β-thalassemia. Healthcare resource utilization (HCRU) has been analyzed in TDT in the US, but there is limited research on the asso

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Damtie, Destaw, and Yalemtsehay Mekonnen. "Toxicity and Oviposition Deterrent Activities of Thyme Essential Oils against Anopheles arabiensis." Psyche: A Journal of Entomology 2021 (June 7, 2021): 1–7. http://dx.doi.org/10.1155/2021/6684156.

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Background. Malaria is one of the deadliest mosquito-borne diseases in sub-Saharan Africa and Ethiopia. Owing to their costs and environmental issues, synthetic insecticides are poor choices to control mosquitoes. Plant-based products can be considered as safe and biodegradable alternatives. The present study aimed to test the toxicity and oviposition deterrent activities of Thymus serrulatus and Thymus schimperi essential oils (EOs) against Anopheles arabiensis. Methods. Thyme EOs were extracted by hydrodistillation using the Clevenger-type apparatus. They were named Tar, Ala, and Yil after t

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Grigore, Daniela-Mihaela, Silvia Mironeasa, Georgeta Ciurescu, Mădălina Ungureanu-Iuga, Ana Batariuc, and Narcisa Elena Babeanu. "Carcass Yield and Meat Quality of Broiler Chicks Supplemented with Yeasts Bioproducts." Applied Sciences 13, no. 3 (2023): 1607. http://dx.doi.org/10.3390/app13031607.

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The utilization of synthetic additives (vitamins, proteins, and pigments) in broiler chicks’ feeds may cause problems in the future, such as competitive availability, extra productive induced costs, and human health risks relayed on sole ingredients commonly used on human and animal food and feeds. A total of 320-day-old broiler chicks were randomly assigned to eight experimental groups (a four × two factorial design), receiving two dietary yeasts, lyophilizate lysates yeasts:brewer’s spent yeasts: Saccharomyces cerevisiae (SC: 0, 0.6, 1 and 1.3 g/kg) and Rhodotorula mucilaginosa (RM: with 0.3

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Aldawood, Asma, Daniel Hind, Simon Rushton, and Becky Field. "Theories, models and frameworks to understand barriers to the provision of mobility-assistive technologies: a scoping review." BMJ Open 14, no. 5 (2024): e080633. http://dx.doi.org/10.1136/bmjopen-2023-080633.

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ObjectivesThere is strong evidence that mobility-assistive technologies improve occupational performance, social participation, educational and employment access and overall quality of life in people with disabilities. However, people with disabilities still face barriers in accessing mobility products and related services. This review aims to summarise and synthesise: (1) theories, models and frameworks that have been used to understand mobility-assistive technology access, (2) determinants of access and (3) gaps in knowledge.DesignA scoping review using the five-step framework by Arksey and

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Rumiantsev, Anatolii, Lesya Pobochenko, Zoia Pichkurova, Tatiana Tolpezhnikova, Tatiana Kovbych, and Dmytro Lyashov. "THE IMPACT OF GLOBAL DIGITALIZATION ON THE UKRAINIAN LABOR MARKET DEVELOPMENT." Financial and credit activity problems of theory and practice 5, no. 46 (2022): 334–48. http://dx.doi.org/10.55643/fcaptp.5.46.2022.3854.

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The article examines the labor market of Ukraine (LMU) as a systemic formation. The features of its development in the conditions of its global distribution and intensive use of digital technologies in the world economy are determined. It was substantiated the expediency of taking into account such modern trends in the development of the world, regional and domestic labor market as: a) the digitalization transformation of regional labor markets takes place, especially the European Union, b) on the global, regional and national labor markets level is the untimely legal, institutional and financ

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Tanaka, E., E. Inoue, R. Sakai, I. Katsuhiko, A. Shoji, and M. Harigai. "POS0551 MEDICAL COSTS FOR PATIENTS STARTING TREATMENT FOR RHEUMATOID ARTHRITIS WHO HAVE COMORBID DIABETES MELLITUS IN JAPAN." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 510.1–510. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2770.

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Background:Rheumatoid arthritis (RA) patients can experience various comorbidities1. The incidence of diabetes mellitus (DM) is reported higher in patients with RA2 and comorbid DM is likely to affect treatment outcomes3 and then healthcare resource uses, however, no previous study has not focused on it.Objectives:To evaluate medical costs and resource use in patients starting treatment for RA with and without DM using a large claims database in Japan.Methods:We used a large Japanese administrative claims database constructed by the Japan Medical Data Center (JMDC)4. Patients with the Internat

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Mancuso, Teresina, Luca Croce, and Monica Vercelli. "Total Brood Removal and Other Biotechniques for the Sustainable Control of Varroa Mites in Honey Bee Colonies: Economic Impact in Beekeeping Farm Case Studies in Northwestern Italy." Sustainability 12, no. 6 (2020): 2302. http://dx.doi.org/10.3390/su12062302.

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Honey bee colonies are affected by many threats, and the Varroa mite represents one of the most important causes of honey bee disease. The control of the Varroa population is managed by different methods, and in recent years, biotechnical practices are considered preferable to chemical approaches in order to safeguard honey bee health and avoid residues in bee products as well as the appearance of acaricide resistance. However, little is known about the economic performance of beekeeping exploitations in relation to the methods used for tackling Varroa. This study aims to investigate the econo

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Monti, Luciano. "Generational Divide: A New Model to Measure and Prevent Youth Social and Economic Discrimination." Review of European Studies 9, no. 3 (2017): 151. http://dx.doi.org/10.5539/res.v9n3p151.

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Measures concerning intergenerational inequality generally refer to youth unemployment or youth household income and wealth. The common conclusion is that the generational gap is represented by negative trend of youth unemployment and NEETS. In this paper, I argue that this phenomenon is not the cause of intergenerational unfairness, but one of its effects.The pioneering efforts to measure the intergenerational fairness through a set of multidimensional indicators are the starting point for deeper analysis. The purpose of this paper, however, is not only to measure unfairness, but to quantify

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Ferreccio, C., S. Maidana, R. Tau, et al. "Reduction of in vitro viral replication of caprine alphaherpesvirus 1 (CPHV-1) through natural antiviral treatment with plant extracts." Revista Veterinaria 36, no. 1 (2025): 1–8. https://doi.org/10.30972/vet.3618088.

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Caprine herpesvirus 1 (CpHV-1) is distributed worldwide, causing significant economic losses. The application of acyclovir interferes with viral replication to varying degrees of efficacy, but it does not prevent the establishment of latency. Due to the costs and side effects associated with synthetic drugs, the search for new chemotherapeutic agents is essential for the treatment and control of viral diseases. The objective of this study is to evaluate and compare the in vitro antiviral activity of three native plants from Argentina as a therapeutic antiviral treatment against CpHV-1. Larrea

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Xie, Jiadong, Jeffrey Xu Yu, and Yingfan Liu. "Fast Approximate Similarity Join in Vector Databases." Proceedings of the ACM on Management of Data 3, no. 3 (2025): 1–26. https://doi.org/10.1145/3725403.

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Recent advancements in deep learning, particularly in embedding models, have enabled the effective representation of various data types such as text, images, and audio as vectors, thereby facilitating semantic analysis. A large number of massive vector datasets are maintained in vector databases. Approximate similarity join is a core operation in vector database systems that joins two datasets, and outputs all pairs of vectors from the two datasets, if the distance between such a pair of two vectors is no more than a specified value. Existing approaches for similarity join are selection-based

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Rudakova, A. V., and Т. V. Korotaeva. "Pharmacoeconomic study of active psoriatic arthritis treatment." FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology 17, no. 4 (2025): 504–12. https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.291.

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Objective: to conduct a clinical and economic analysis of the therapy for adult patients with psoriatic arthritis (PsA) using netakimab, a Russian interleukin-17 inhibitor, in comparison with other biological (b) and targeted synthetic (ts) disease-modifying antirheumatic drugs (DMARDs), available on the pharmaceutical market of the Russian Federation.Material and methods. The evaluation of clinical and economic effectiveness was carried out from the perspective of the healthcare system for a population of patients with active PsA, based on the results of a network meta-analysis. Clinical effe

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SADOWSKA, BEATA. "The financial results of Polish State Forests and profit distribution – in the opinions of stakeholders." Zeszyty Teoretyczne Rachunkowości 47, no. 3 (2023): 133–56. http://dx.doi.org/10.5604/01.3001.0053.7699.

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Purpose: The main aim of the study is to present and evaluate the essence, the principles of determining (measuring), and the means of presenting the result of Polish State Forests (LP) in financial reporting, as well as the presentation of the initial distribution of profit.Methodology/approach: The considerations in the study are contrasted with selected authors from the source literature. The methods of critical analysis and synthesis, inference, and a case study were used. The data for the analyses were collected from the financial and economic reports of LP for 2011–2021 and from the acco

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Horton, Dustin, Joel T. Johnson, Ismail Baris, et al. "Wildfire Threshold Detection and Progression Monitoring Using an Improved Radar Vegetation Index in California." Remote Sensing 16, no. 16 (2024): 3050. http://dx.doi.org/10.3390/rs16163050.

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To address the recent increase in wildfire severity and incidence, as well as the subsequent financial and physical costs, forest managers and wildland firefighting agencies rely on remotely sensed products for better decision-making and mitigation efforts. To address the remote sensing needs of these agencies, which include high spatial resolution, immunity to atmospheric and solar illumination effects, and day/night capabilities, the use of synthetic aperture radar (SAR) is under investigation for application in current and upcoming systems for all phases of a wildfire. Focusing on the activ

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Zinchenko, O. A. "Development of new approaches to information transparency diagnostics in the regional market." Economies' Horizons, no. 3-4(18) (February 14, 2022): 14–26. http://dx.doi.org/10.31499/2616-5236.3-4(18).2021.247305.

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The purpose of the research is to develop a methodological approach to the information transparency diagnostics in regional markets based on the analysis of the transaction costs dynamics. Methodology. To achieve this goal, methods of logical generalization, dialectical, system-structural methods, methods of analysis, synthesis and grouping, regression analysis were used. Results. It is proved that the level and structure of transaction costs are influenced by the peculiarities of the functioning of a particular market, so the approbation of the approach took place in a regional re

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Du, HaiChao, Li Lv, Hongliang Wang, and An Guo. "A novel method for detecting credit card fraud problems." PLOS ONE 19, no. 3 (2024): e0294537. http://dx.doi.org/10.1371/journal.pone.0294537.

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Credit card fraud is a significant problem that costs billions of dollars annually. Detecting fraudulent transactions is challenging due to the imbalance in class distribution, where the majority of transactions are legitimate. While pre-processing techniques such as oversampling of minority classes are commonly used to address this issue, they often generate unrealistic or overgeneralized samples. This paper proposes a method called autoencoder with probabilistic xgboost based on SMOTE and CGAN(AE-XGB-SMOTE-CGAN) for detecting credit card frauds.AE-XGB-SMOTE-CGAN is a novel method proposed fo

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Tanaka, E., E. Inoue, R. Sakai, I. Katsuhiko, A. Shoji, and M. Harigai. "POS0554 MEDICAL COST AND RESOURCE USE IN PATIENTS STARTING TREATMENT FOR RHEUMATOID ARTHRITIS TREATED WITH AND WITHOUT CORTICOSTEROIDS IN JAPAN." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 511.2–512. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2805.

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Background:The 2019 update of the European League Against Rheumatism (EULAR) treatment recommendations strongly recommends co-administration of corticosteroids (CSs) with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) in patients with RA as bridging therapy to improve the success rate of the first-line treatment and to avoid disease flare-ups1; however, current treatment guidelines for RA in Japan do not clearly mention about their use. Poor disease management after the initial diagnosis can affect the overall use of health services and the economic burden on patients.

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Operti, Maria Camilla, Alexander Bernhardt, Jeanette Pots, et al. "Translating the Manufacture of Immunotherapeutic PLGA Nanoparticles from Lab to Industrial Scale: Process Transfer and In Vitro Testing." Pharmaceutics 14, no. 8 (2022): 1690. http://dx.doi.org/10.3390/pharmaceutics14081690.

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Poly(lactic-co-glycolic acid) (PLGA) nanoparticle-based drug delivery systems are known to offer a plethora of potential therapeutic benefits. However, challenges related to large-scale manufacturing, such as the difficulty of reproducing complex formulations and high manufacturing costs, hinder their clinical and commercial development. In this context, a reliable manufacturing technique suitable for the scale-up production of nanoformulations without altering efficacy and safety profiles is highly needed. In this paper, we develop an inline sonication process and adapt it to the industrial s

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Auliya, Diba G., Soni Setiadji, Zulfi Mofa Agasa, Fitrilawati, Norman Syakir, and Risdiana. "Synthesis of Low Viscosity Polydimethylsiloxane Using Low Grade of Octamethylcyclotetrasiloxane." Materials Science Forum 1028 (April 2021): 365–70. http://dx.doi.org/10.4028/www.scientific.net/msf.1028.365.

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Polydimethylsiloxane (PDMS) has been widely used as a vitreous humour substitution in vitreoretinal surgery. Due to its limited availability and increasing domestic needs, the price of PDMS in Indonesia became very expensive. Previously, we reported the synthesized of PDMS from a high grade of monomer of 98% of Octamethylcyclotetrasiloxane (D4) and found that all PDMS samples produced high quality samples similar to that of commercial one. However, by considering the ease of obtaining raw materials and also the production costs, the synthesis of PDMS using monomer which easy to be found in Ind

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Syromyatnikov, Denis, Varvara Druzyanova, Aleksandr Beloglazov, Alexander Bakshtanin, and Tatiana Matveeva. "Evaluation of the Economic Profitability of Using Renewable Energy Sources in Agro-Industrial Companies." International Journal of Renewable Energy Development 10, no. 4 (2021): 827–37. http://dx.doi.org/10.14710/ijred.2021.37908.

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The study of the impact of the availability of renewable energy sources (RES) on the competitiveness and cost reduction opportunities is an actual objective for agro-industrial enterprises in the present time. The purpose of this paper was to develop a methodological approach based on a questionnaire survey, an integrated indicator of enterprise competitiveness, a model for assessing energy conservation costs, and regression analysis combined with a hierarchical synthesis of 20 Russian agro-industrial companies. The solution of the problem of nonlinear optimization of agro-industrial companies

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Syngle, D., I. Verma, K. Chauhan, S. Patyal, and A. Syngle. "AB0510 COST-EFFECTIVE ANALYSIS OF GENERIC TARGETED SYNTHETIC DISEASE-MODIFYING ANTI-RHEUMATIC DRUG - TOFACITINIB IN RHEUMATOID ARTHRITIS (TIRA CEA STUDY)." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1449.2–1449. http://dx.doi.org/10.1136/annrheumdis-2023-eular.5306.

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BackgroundWith the introduction of generic version of tsDMARD tofacitinib in different parts of the world, its important to perform a cost-effective analysis of introducing generic tofacitinib to the current treatment sequence for patients with moderate-to-severe rheumatoid arthritis who have inadequate response or intolerance to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs-IR).ObjectivesPerform pharmacoeconomic analysis of introducing generic tofacitinib into the current treatment sequence for patients with moderate-to-severe rheumatoid arthritis who are csDMARDs-IR.

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Kasprzyk, Leszek, Andrzej Tomczewski, Robert Pietracho, et al. "Optimization of a PV-Wind Hybrid Power Supply Structure with Electrochemical Storage Intended for Supplying a Load with Known Characteristics." Energies 13, no. 22 (2020): 6143. http://dx.doi.org/10.3390/en13226143.

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An important aspect of the off-grid utilization of hybrid generation systems is the integration of energy storage facilities into their structures, which allows for improved power supply reliability. However, this results in a significant increase in the cost of such systems. Therefore, it is justified to use optimization resulting in the minimization of the selected economic indicator taking into account the most important technical constraints. For this reason, this work proposes an algorithm to optimize the structure of a hybrid off-grid power distribution system (with electrochemical energ

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