Journal articles: 'The Ultimate Guide to E.D'

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Leitáo, V. "The ultimate guide to the vi and ex text editors." Advances in Engineering Software 14, no. 4 (January 1992): 305. http://dx.doi.org/10.1016/0965-9978(92)90010-d.

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Laudicina, Matthew. "Book Review: D-Day: The Essential Reference Guide." Reference & User Services Quarterly 58, no. 1 (October 10, 2018): 62. http://dx.doi.org/10.5860/rusq.58.1.6852.

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The Normandy Landings, commonly referred to as D-Day, was a pivotal moment in the course of the Second World War. This successful invasion of the northwestern beaches of France marked the beginning of the Allied liberation of the western front, and would ultimately lead to the defeat of Nazi Germany. D-Day: The Essential Reference Guide successfully provides quality reference information on this major historical event.

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Yulan, Wang, Dong Zhao, Wei Lu, and Lei Fan. "Experimental Research on Destruction Mode and Anchoring Performance of Carbon Fiber Phyllostachys pubescens Anchor Rod with Different Forms." Advances in Civil Engineering 2018 (2018): 1–14. http://dx.doi.org/10.1155/2018/1841267.

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The anchoring technology is extensively applied in reinforcing protection of the earth relics. Now that no specification is available for different new anchor rods in earth relics protection due to diversified destruction modes of earth relics and complexity of engineering technology conditions, it is urgent to guide reinforcing design and construction with a complete detailed anchor rod research document. With the new carbon fiber Phyllostachys pubescens anchor rod as the research object, six lots of in situ tests are designed to, respectively, study the destruction mode and anchoring performance of the carbon fiber Phyllostachys pubescens anchor rod under different anchor length L, anchor rod diameter D, bore diameter H, grouting material S, rib spacing R, and inclination angle A in this paper. By studying load shift curve experiment in drawing of the anchor rod, the destruction mode and ultimate bearing capacity of the carbon fiber Phyllostachys pubescens anchor rod in different experiment lots are obtained, and the concept of permitted application value N in anchor rod design is proposed. By studying strain distribution characteristics of anchor rods in experimental lots along the length direction under action of the permitted application value N and combining the existing destruction mode and ultimate bearing capacity, this paper analyzes influences of L, D, H, S, R, and A on anchoring effect of the carbon fiber Phyllostachys pubescens anchor rod; gives the reasonable value range of L, D, H, and R when the carbon fiber Phyllostachys pubescens anchor rod is used for reinforcing design of the earth relics; and provides favorable experiment basis for reinforcing design of the earth relics based on the carbon fiber Phyllostachys pubescens anchor rod.

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Shi, Peiying, Chunlei Yang, Ya Su, Liying Huang, Xinhua Lin, and Hong Yao. "Simultaneous Determination of Five Phenolic Acids and Four Flavonoid Glycosides in Rat Plasma Using HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Intravenous Administration of Kudiezi Injection." Molecules 24, no. 1 (December 25, 2018): 64. http://dx.doi.org/10.3390/molecules24010064.

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This study has developed a reliable and precise high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of five phenolic acids and four flavonoid glycosides in rat plasma after a single intravenous administration of Kudiezi injection (KI). Chromatographic separation was carried out on an Ultimate®XB-C18 column (4.6 × 100 mm, 3.5 μm) using a gradient elution program with a mobile phase consisting of water containing 0.5% acetic acid and acetonitrile at a flow rate of 0.6 mL/min. Detection was performed on a triple-quadrupole tandem mass spectrometry using multiple reaction monitoring in negative electrospray ionization mode. The calibration curves of all analytes showed good linearity (R2 > 0.990). The results of selectivity, intra-day and inter-day precisions, extraction recoveries, matrix effects and stability were satisfactory. Pharmacokinetic parameters showed that luteolin-7-O-β-d-gentiobioside, luteolin-7-O-β-d-glucuronide, luteolin-7-O-β-d-glucoside and apigenin-7-O-β-d-glucuronide were eliminated quickly (0.07 h < t1/2 < 0.66 h), whereas 5-caffeoylquinic acid, caftaric acid, chlorogenic acid, 4-caffeoylquinic acid and caffeic acid were eliminated relatively slowly (2.22 h < t1/2 < 6.09 h) in rat blood. The pharmacokinetic results would be valuable to identify bioactive constituents, elucidate mechanisms of pharmacological actions or adverse drug reactions and guide the rational clinical use of KI.

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Mondello, Stefania, Firas Kobeissy, Yehia Mechref, Jingfu Zhao, Farid R. Talih, Filomena Cosentino, Elena Antelmi, Monica Moresco, Giuseppe Plazzi, and Raffaele Ferri. "Novel biomarker signatures for idiopathic REM sleep behavior disorder." Neurology 91, no. 18 (September 26, 2018): e1710-e1715. http://dx.doi.org/10.1212/wnl.0000000000006439.

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ObjectiveTo perform a rigorous in-depth proteomics analysis to identify circulating biomarker signatures for idiopathic REM sleep behavior disorder (RBD), capable of providing new insights into the underlying pathogenic mechanisms and putative α-synuclein-related neurodegenerative processes.MethodsSerum samples from patients with idiopathic RBD (n = 9) and healthy controls (n = 10) were subjected to a thorough liquid chromatography–mass spectrometry (MS)/MS proteomics analysis using ultimate 3,000 nanoLC interfaced to an ESI-orbitrap velos. Data were analyzed with a systems biology approach to identify altered pathways in RBD.ResultsWe identified 259 proteins, 11 of which displayed significantly altered expression level in patients with RBD as compared to controls. Significant reduction in serum levels of dopamine β-hydroxylase (DBH) and vitamin D binding protein (GC) were consistent with alterations in the norepinephrinergic (NErgic) and dopaminergic systems, respectively. Additional altered protein profiles indicated that immunity, inflammation, complement, and coagulation also play a role in RBD pathophysiology.ConclusionsOur results shed light on the protein signature profile, molecular pathways, and mechanisms involved in the pathogenesis of RBD and its clinical manifestation. This knowledge opens a new avenue towards more accurate and timely diagnosis and characterization of RBD, which might ultimately translate into new therapeutic strategies with disease-modifying effects. Further evaluation of the identified markers is required to confirm their diagnostic value and potential to guide clinical decision-making.

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Moreton, Alan J., Arthur L. Wolek, Garrett G. Hoffman, Juan J. Goñi, and José M. Rodriguez. "Performance of Precast Segmental Structures with External Tendons Under Moderate Seismic Conditions." Transportation Research Record: Journal of the Transportation Research Board 1696, no. 1 (January 2000): 216–23. http://dx.doi.org/10.3141/1696-66.

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The 1998 draft of the AASHTO Guide Specifications for Segmental Bridges restricts the use of external posttensioning tendons in regions of severe seismic activity, Seismic Performance Category (SPC) C and SPC D, by requiring that at least 50 percent of the tendons be internal to the concrete. This requirement has also been applied to selected projects in SPC B designed before or during the development of the 1998 draft. A case study is presented that substantiates the use of purely externally posttensioned structures in SPC B and indicates that the requirement may not even be necessary for SPCs C and D. The case study concerns a project in which precast segmental superstructures carry a light-rail access system to the John F. Kennedy International Airport in New York. Two different precast segmental superstructures with external tendons are modeled using a multimode spectral analysis. The goal is to determine the stress levels under the worst possible seismic conditions for SPC B and, in particular, to establish whether the joints would open or crack and the external tendons would suffer any distress. For both models, results show conclusively that the forces, moments, and stresses in the superstructure are less severe than under normal service level loads. Thus, there is no risk of cracking or opening of joints, and the external tendons experience no increase in stress over their normal service conditions. In addition, research shows that there is no significant difference in behavior between external and internal tendons for loads within ultimate conditions.

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Wieringa, Edwin. "The Illusion of an Allusion: A Soothing Song for the Exiled Prince Dipasana (d. ca 1840) in Ambon." Journal of the Royal Asiatic Society 10, no. 2 (July 2000): 193–204. http://dx.doi.org/10.1017/s1356186300012451.

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Javanese literature can boast a distinct genre of works about the adventures of wandering students/scholars, who travel about the countryside in pursuit of esoteric knowledge. Journeying and undergoing various trials and tribulations on the way is regarded in Javanese culture as an ascetic practice, preparatory to ultimate enlightenment. An early, pre-Islamic representative of this genre is the Kidung Subrata, dated 1541. The best-know examples, at least by name, i.e. the Cĕnṭini and Jatiswara, probably originate from the beginning of the seventeenth century. In the course of time these two stories were constantly reworked until by the beginning of the nineteenth century they reached massive proportions and were made into storehouses of encyclopaedic knowledge of all kinds of things Javanese. The so-called Major Cěntini, compiled in 1814 at the Surakarta Crown Prince's court, has hitherto received most attention. Quite a few scholars, guided by Pigeaud's table of contents, have tapped this source for information on many topics.

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Yangin, Hatice, İlkay Boz, Arzu Akpinar, and Şule Çiftcioğlu. "Theory-Based Nursing Research: A Qualitative Evaluation of the Experiences of Nurse Educators." Research and Theory for Nursing Practice 34, no. 3 (August 1, 2020): 223–36. http://dx.doi.org/10.1891/rtnp-d-19-00111.

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Background and PurposeInvestigation of thoughts, experiences, and attitudes of nurse educators regarding theory-based research is important. Ultimately, nurse educators are the producers of nursing knowledge and providers of education. The aim of this study is to understand the experiences of nurse educators in selecting and using nursing theory to guide and inform the quality of their research.MethodsThis study has a descriptive phenomenological design, and the sample was comprised of nine nurse educators who had experience with theory-based research. The data were collected via in-depth personal interviews using a semi-structured survey form. The data were analyzed with content analysis as described by Graneheim and Lundman.ResultsFour themes emerged from the results of the study: “awareness of theory,” “meaning of theory-based research,” “harmony with the theory,” and “changing towards scholarship,” with 10 subthemes. It was determined that theory-based research helps nurse educators to improve themselves in academic and personal terms.Implications for PracticeAlthough the process of translating theory into research presents several challenges, all participants expressed that theory-based research contributed to their “theory advancing nursing science.”

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Jo, Yeong Ran, Chan Woo Cho, Jee Eun Kim, Sung Joo Lee, and Jea Wook Yoon. "A Framework for Evaluating R&D Process Using a Best Practice Approach." Advanced Materials Research 433-440 (January 2012): 1620–28. http://dx.doi.org/10.4028/www.scientific.net/amr.433-440.1620.

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Recently a strong increase in R&D investment has encouraged a firm to create a more effective and efficient R&D process, which allows it to save time and costs significantly. In order to build such a process, a firm should be able to evaluate its process, based on which the process can be improved. With all its importance and value, however, the previous studies on R&D process have seldom focused on the method of evaluating the process. Therefore this study aims to develop a framework for evaluating R&D process. For the purpose, CMMI (Capability Maturity Model Integrated) is used as a main method, which is a process improvement approach that provides organizations with the essential elements of effective processes that ultimately improve their performance and thus considered suitable for this research. We tried to develop a framework for evaluating R&D process based on the CMMI approach by modifying it to be suitable for measuring R&D performance where the essential elements for effective R&D process are obtained from the literature on best practices. A simple case study was conducted to illustrate how the proposed framework could be applied. The research results are expected to guide R&D process improvement across a project, a division, or an entire organization.

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Sprintall, Janet, Victoria J. Coles, Kevin A. Reed, Amy H. Butler, Gregory R. Foltz, Stephen G. Penny, and Hyodae Seo. "Best Practice Strategies for Process Studies Designed to Improve Climate Modeling." Bulletin of the American Meteorological Society 101, no. 10 (October 1, 2020): E1842—E1850. http://dx.doi.org/10.1175/bams-d-19-0263.1.

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AbstractProcess studies are designed to improve our understanding of poorly described physical processes that are central to the behavior of the climate system. They typically include coordinated efforts of intensive field campaigns in the atmosphere and/or ocean to collect a carefully planned set of in situ observations. Ideally the observational portion of a process study is paired with numerical modeling efforts that lead to better representation of a poorly simulated or previously neglected physical process in operational and research models. This article provides a framework of best practices to help guide scientists in carrying out more productive, collaborative, and successful process studies. Topics include the planning and implementation of a process study and the associated web of logistical challenges; the development of focused science goals and testable hypotheses; and the importance of assembling an integrated and compatible team with a diversity of social identity, gender, career stage, and scientific background. Guidelines are also provided for scientific data management, dissemination, and stewardship. Above all, developing trust and continual communication within the science team during the field campaign and analysis phase are key for process studies. We consider a successful process study as one that ultimately will improve our quantitative understanding of the mechanisms responsible for climate variability and enhance our ability to represent them in climate models.

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Wemmer, David E. "The ultimate guide." Trends in Biochemical Sciences 25, no. 11 (November 2000): 577–78. http://dx.doi.org/10.1016/s0968-0004(00)01650-9.

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Knippertz, Peter, Hugh Coe, J. Christine Chiu, Mat J. Evans, Andreas H. Fink, Norbert Kalthoff, Catherine Liousse, et al. "The DACCIWA Project: Dynamics–Aerosol–Chemistry–Cloud Interactions in West Africa." Bulletin of the American Meteorological Society 96, no. 9 (September 1, 2015): 1451–60. http://dx.doi.org/10.1175/bams-d-14-00108.1.

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Abstract Massive economic and population growth, and urbanization are expected to lead to a tripling of anthropogenic emissions in southern West Africa (SWA) between 2000 and 2030. However, the impacts of this on human health, ecosystems, food security, and the regional climate are largely unknown. An integrated assessment is challenging due to (a) a superposition of regional effects with global climate change; (b) a strong dependence on the variable West African monsoon; (c) incomplete scientific understanding of interactions between emissions, clouds, radiation, precipitation, and regional circulations; and (d) a lack of observations. This article provides an overview of the DACCIWA (Dynamics–Aerosol–Chemistry–Cloud Interactions in West Africa) project. DACCIWA will conduct extensive fieldwork in SWA to collect high-quality observations, spanning the entire process chain from surface-based natural and anthropogenic emissions to impacts on health, ecosystems, and climate. Combining the resulting benchmark dataset with a wide range of modeling activities will allow (a) assessment of relevant physical, chemical, and biological processes; (b) improvement of the monitoring of climate and atmospheric composition from space; and (c) development of the next generation of weather and climate models capable of representing coupled cloud–aerosol interactions. The latter will ultimately contribute to reduce uncertainties in climate predictions. DACCIWA collaborates closely with operational centers, international programs, policymakers, and users to actively guide sustainable future planning for West Africa. It is hoped that some of DACCIWA’s scientific findings and technical developments will be applicable to other monsoon regions.

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Gleason, R. L., L. A. Taber, and J. D. Humphrey. "A 2-D Model of Flow-Induced Alterations in the Geometry, Structure, and Properties of Carotid Arteries." Journal of Biomechanical Engineering 126, no. 3 (June 1, 2004): 371–81. http://dx.doi.org/10.1115/1.1762899.

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Evidence from diverse investigations suggests that arterial growth and remodeling correlates well with changes in mechanical stresses from their homeostatic values. Ultimately, therefore, there is a need for a comprehensive theory that accounts for changes in the 3-D distribution of stress within the arterial wall, including residual stress, and its relation to the mechanisms of mechanotransduction. Here, however, we consider a simpler theory that allows competing hypotheses to be tested easily, that can provide guidance in the development of a 3-D theory, and that may be useful in modeling solid-fluid interactions and interpreting clinical data. Specifically, we present a 2-D constrained mixture model for the adaptation of a cylindrical artery in response to a sustained alteration in flow. Using a rule-of-mixtures model for the stress response and first order kinetics for the production and removal of the three primary load-bearing constituents within the wall, we illustrate capabilities of the model by comparing responses given complete versus negligible turnover of elastin. Findings suggest that biological constraints may result in sub-optimal adaptations, consistent with reported observations. To build upon this finding, however, there is a need for significantly more data to guide the hypothesis testing as well as the formulation of specific constitutive relations within the model.

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Zhang, Yi. "Construction of Bid Evaluation Index System in Government Public Project Green Procurement in China Based on D-S Evidence Theory." Sustainability 12, no. 2 (January 16, 2020): 651. http://dx.doi.org/10.3390/su12020651.

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It is of great theoretical and practical significance to construct a bid evaluation index system characterized by green for government public project green procurement. With the combination of sustainable development theory and system theory, and with the goal of government public project procurement as the guide, this paper uses the documentary research method, questionnaire survey method, and expert consultation method to analyze the influential factors of bid evaluation for government public project procurement with the perspective of green development from the aspects of qualification, economy, technology, management, and public welfare and to construct the bid evaluation index system for government public project green procurement; based on Dempster-Shafer evidence theory, using the D-S evidence synthesis method to construct a comprehensive judgment matrix for group decision-making (which effectively solves the problem of synthesizing expert opinions), and combined with the analytic hierarchy process, the index weights are determined. Ultimately, a bid evaluation index system for government public project green procurement is obtained, including 5 first-level indexes, 18 secondary indexes, and 56 tertiary indexes, providing theoretical guidance for the government to implement green procurement in the field of public projects.

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Emond, M., A. Laguë, T. O’Brien, B. Mitra, P. Tardif, N. Le Sage, M. D. Astous, and E. Mercier. "LO45: Incidence of delayed intracranial hemorrhage following a mild traumatic brain injury in patients taking anticoagulants or anti-platelets therapies: systematic review and meta-analysis." CJEM 20, S1 (May 2018): S22. http://dx.doi.org/10.1017/cem.2018.107.

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Introduction: Head injury is a common presentation to all emergency departments. Previous research has shown that such injuries may be complicated by delayed intracranial hemorrhage (D-ICH) after the initial scan is negative. Exposure to anticoagulant or anti-platelet medications (ACAP) may be a risk factor for D-ICH. We have conducted a systematic review and meta-analysis to determine the incidence of delayed traumatic intracranial hemorrhage in patients taking anticoagulants, anti-platelets or both. Methods: The literature search was conducted in March 2017 with an update in April 2017. Keyword and MeSH terms were used to search OVID Medline, Embase and the Cochrane database as well as grey literature sources. All cohort and experimental studies were eligible for selection. Inclusion criteria included pre-injury exposure to oral anticoagulant and / or anti-platelet medication and a negative initial CT scan of the brain (CT1). The primary outcome was delayed intracranial hemorrhage present on repeat CT scan (CT2) within 48 hours of the presentation. Only patients who were rescanned or observed minimally were included. Clinically significant D-ICH were those that required neurosurgery, caused death or necessitated a change in management strategy, such as admission. Results: Fifteen primary studies were ultimately identified, comprising a total of 3801 patients. Of this number, 2111 had a control CT scan. 39 cases of D-ICH were identified, with the incidence of D-ICH calculated to be 1.31% (95% CI [0.56, 2.27]). No more than 12 of these patients had a clinically significant D-ICH representing 0.09% (95% CI [0.00, 0.31]). 10 of them were on warfarin and two on aspirin. There were three deaths recorded and three patients needed neurosurgery. Conclusion: The relatively low incidence suggests that repeat CT should not be mandatory for patients without ICH on first CT. This is further supported by the negligibly low rate of clinically significant D-ICH. Evidence-based assessments should be utilised to indicate the appropriate discharge plan, with further research required to guide the balance between clinical observation and repeat CT.

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Muskiewicz, Marion S. "Sources: Penguins: the Ultimate Guide." Reference & User Services Quarterly 54, no. 3 (2015): 64–65. http://dx.doi.org/10.5860/rusq.54n3.64b.

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Lippi, Giuseppe, and Gian Cesare Guidi. "Laboratory Diagnostics in Septic Disseminated Intravascular Coagulation." European Oncology & Haematology 03, no. 01 (2009): 19. http://dx.doi.org/10.17925/eoh.2009.03.1.19.

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The diagnosis of septic disseminated intravascular coagulation (DIC) relies on clinical signs and symptoms, identification of the underlying disease and results of laboratory testing. Since no single test result alone can definitely establish or rule out the diagnosis, the laboratory diagnostics of septic DIC encompass a combination of tests for which simple diagnostic algorithms are now available. Global tests of haemostasis provide evidence of activation of blood coagulation and, ultimately, consumption of coagulation factors, but their diagnostic efficiency is as yet questionable. Fibrinolytic markers, namely D-dimer, reflect the extent of activation of both coagulation and fibrinolysis, so a normal value can be used in a ruling-out strategy. Decreased levels of the natural inhibitors are frequently observed in patients with septic DIC, but antithrombin and protein C measurements are not incorporated in any of the widely used diagnostic algorithms. Among the inflammatory biomarkers, procalcitonin is currently regarded as the gold standard to differentiate the type of infection and guide antibiotic therapy, but its clinical usefulness in identifying and predicting the outcome of patients with septic DIC is still circumstantial.

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Deborah Stevenson. "The Ultimate Teen Book Guide (review)." Bulletin of the Center for Children's Books 61, no. 9 (2008): 408. http://dx.doi.org/10.1353/bcc.0.0060.

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Adler, Robert. "The ultimate guide to the multiverse." New Scientist 212, no. 2840 (November 2011): 42–47. http://dx.doi.org/10.1016/s0262-4079(11)62920-5.

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McConnell, Mary, Debra Bell, David H. Albert, Michael Card, Susan Card, Linda Dobson, Jessie Wise, and Susan Wise Bauer. "The Ultimate Guide to Home Schooling." Journal of Law and Religion 16, no. 2 (2001): 471. http://dx.doi.org/10.2307/1051681.

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Oetting, William S. "The Ultimate Guide to DMD Variants." Human Mutation 36, no. 4 (March 31, 2015): v. http://dx.doi.org/10.1002/humu.22780.

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Haroldson, Amber. "The Ultimate Guide to Sugars & Sweeteners." Journal of Nutrition Education and Behavior 47, no. 5 (September 2015): 484.e5. http://dx.doi.org/10.1016/j.jneb.2015.04.330.

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Brugge, Roger. "Weather: The ultimate guide to the elements." Weather 51, no. 12 (December 1996): 436. http://dx.doi.org/10.1002/j.1477-8696.1996.tb06179.x.

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Steinman, Lisa M. "Poetry: The Ultimate Guide. By Richard Bradford." European Legacy 17, no. 6 (October 2012): 853–54. http://dx.doi.org/10.1080/10848770.2012.715863.

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Batalden, Karin B. "The Ultimate Guide to Choosing a Medical Specialty." Mayo Clinic Proceedings 79, no. 11 (November 2004): 1473. http://dx.doi.org/10.4065/79.11.1471-a.

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O'Sullivan, Sue. "The ultimate guide to anal sex for women." Reproductive Health Matters 6, no. 12 (January 1998): 187–89. http://dx.doi.org/10.1016/s0968-8080(98)90076-3.

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Klander, Lars, and Janus Press. "Hacker Proof: The Ultimate Guide to Network Security." EDPACS 26, no. 3 (September 1998): 14–15. http://dx.doi.org/10.1201/1079/43275.26.3.19980901/31738.4.

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Katz, David. "Michael Garnice, The Ultimate Guide To Great Reggae." Volume !, no. 13 : 2 (April 21, 2017): 208–10. http://dx.doi.org/10.4000/volume.5169.

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Bissett, Gaby. "The ULTIMATE secret formula – our guide for success." Dental Nursing 15, no. 5 (May 2, 2019): 216–18. http://dx.doi.org/10.12968/denn.2019.15.5.216.

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What character traits do you think are needed for a long and fruitful career? Here, we learn from award winners and educators on what you need to tweak, what is cherished – and what you need to lose in order to get the best out of your role

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Johns, Gregg A. "The Ultimate Hitchhiker's Guide to Borderline Personality Organization." Contemporary Psychology 49, no. 6 (December 2004): 774–76. http://dx.doi.org/10.1037/004878.

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Hamilton, Kate. "XSLT: The Ultimate Guide to Transforming Web Data." Markup Languages: Theory and Practice 3, no. 4 (September 1, 2001): 480–82. http://dx.doi.org/10.1162/109966202760152266.

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Matthews, Annette. "The ultimate guide: PPE and skin health hacks." Dental Nursing 17, no. 3 (March 2, 2021): 118–19. http://dx.doi.org/10.12968/denn.2021.17.3.118.

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Blanche, Pierre-Alexandre. "Toward the Ultimate 3-D Display." Information Display 28, no. 2-3 (February 2012): 32–37. http://dx.doi.org/10.1002/j.2637-496x.2012.tb00475.x.

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Paik, Jeom Kee. "A Guide for the Ultimate Longitudinal Strength Assessment of Ships." Marine Technology and SNAME News 41, no. 03 (July 1, 2004): 122–39. http://dx.doi.org/10.5957/mt1.2004.41.3.122.

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The aim of the present paper is to establish a practical guide for the ultimate longitudinal strength assessment of ships. The ultimate hull girder strength of a ship hull can be calculated using either the progressive collapse analysis method or closed-form design formulas. In the present paper, both the progressive collapse analysis method and the design formulas are presented. A comparison between the progressive collapse analysis results and the design formula solutions for merchant cargo ship hulls is undertaken. The total design (extreme) bending moment of a ship hull is estimated as the sum of the still-water and wave-induced bending moment components as usual. The safety measure of a ship hull is then defined as a ratio of the ultimate longitudinal strength to the total design bending moment. The developed guidelines are applied to safety measure calculations of merchant ship hulls with respect to hull girder collapse. It is concluded that the guidance and insights developed from the present study will be very useful for the ultimate limit state design of newly built ships as well as the safety measure calculations of existing ship hulls. The essence of the proposed guide shall form ISO code 18072-2: Ships and Marine Technology— Ship Structures—Part 2: Requirements of Their Ultimate Limit State Assessment.

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Vargas, Jorge A. "Mexican Law on the Web: The Ultimate Research Guide." International Journal of Legal Information 32, no. 1 (2004): 34–108. http://dx.doi.org/10.1017/s0731126500003905.

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Today, there are literally hundreds of online resources which contain information on Mexican law and related subjects with varying degrees of authoritativeness, accuracy and accessability. This note does not include information on Mexican legal materials provided by commercial companies, paid subscribers or law firms in the U.S. or Mexico.

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Phark, Jin-Ho, and Giuseppe Romeo. "Dental Anatomical Combinations : A Guide to Ultimate Dental Esthetics." Smile Dental Journal 12, no. 3 (September 2017): 10–20. http://dx.doi.org/10.12816/0044019.

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Kara, Jay. "The ultimate guide to your at-home fitness regime." Dental Nursing 16, no. 6 (June 2, 2020): 276–77. http://dx.doi.org/10.12968/denn.2020.16.6.276.

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Bird, Drayton, and Robin Fairlie. "Write to Sell — The Ultimate Guide to Great Copywriting." Journal of Direct, Data and Digital Marketing Practice 10, no. 1 (July 2008): 96–98. http://dx.doi.org/10.1057/dddmp.2008.18.

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Shuker, Roy. "Review & Booknote: The Ultimate Guide to Science Fiction." Media International Australia 85, no. 1 (November 1997): 126–27. http://dx.doi.org/10.1177/1329878x9708500133.

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Liverpool and Lancaster Medical Schools, Medical Students, and Nick Mullen. "The ultimate alphabet GP guide to unusual psychiatric disorders." Morecambe Bay Medical Journal 8, no. 4 (August 1, 2019): 101–7. http://dx.doi.org/10.48037/mbmj.v8i4.62.

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Hanaoka, Mimi. "The World in a Book: Al-Nuwayri an the Islamic Encyclopedic Tradition." American Journal of Islamic Social Sciences 35, no. 3 (July 1, 2018): 72–76. http://dx.doi.org/10.35632/ajiss.v35i3.482.

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Elias Muhanna’s The World in a Book: Al-Nuwayri and the Islamic Ency- clopedic Tradition is an erudite, scrupulously researched, and eminently readable book that marks a significant contribution to studies in Arabic lit- erature, Mamluk history, and the production and circulation of knowledge in the medieval Islamicate world. Muhanna successfully analyzes—over the course of 232 pages with almost a dozen images and as many tables—the monumental, 31-volume encyclopedic compendium that consists of over two million words, titled Nihāyat al-arab fī funūn al-adab (The Ultimate Ambition in the Arts of Erudition), composed by Shihāb al-Dīn Aḥmad ibn ‘Abd al-Wahhāb al-Nuwayrī, an Egyptian bureaucrat and scholar, during the early fourteenth century. Muhanna’s goals are to consider why al-Nuwayrī composed his ambi- tious work; to analyze the disciplines al-Nuwayrī’s work encompassed and the models, sources, and methods that guided its composition; and to trace its reception among al-Nuwayrī’s contemporaries as well as its later recep- tion in Europe and the Islamicate world. Centering these questions on The Ultimate Ambition, Muhanna analyzes Arabic encyclopedism, a phenom- enon that reached its zenith in Egypt and Syria during the thirteenth to fifteenth centuries. Muhanna challenges the argument that the rise in encyclopedism re- flected anxiety about the Mongol invasions and fears about the obliteration of civilization’s knowledge and heritage. He instead argues that encyclope- dists such as al-Nuwayrī were motivated by various factors, “chief among them the feeling of an overcrowding of authoritative knowledge in Cairo and Damascus, the great school cities of the empire” (3) which, coupled with the expansion of higher education and the migration patterns of scholars in West and Central Asia, meant that there were “new texts available for study and prompting the formation of new genres and knowledge practices” (3). The story of al-Nuwayrī is, thus, a story about the production, reception, and transmission of knowledge. Muhanna’s primary raconteurs are schol- ars of Mamluk history and historiography, Islamicate literature, and studies in the transmission of knowledge, including T. Bauer, J. Berkey, A. Blair, M. Chamberlain, L. Guo, K. Hirschler, H. Kilpatrick, D. Little, L. Northrup, C. Petry, J. Schmidt, M. van Berkel, and G. van Gelder. The World in a Book is both sweeping and specific, and it considers al-Nuwayrī’s compendium directly—not merely as a source to reconstruct Mamluk history—and assesses why encyclopedism surged during the thir- teenth through fifteenth centuries. Amongst the genres of medieval Arabic Islamicate literature to which scholars have directed their attention during the past several decades—such as adab, poetry, mirrors for princes, histo- ries, chronicles, hadith collections, and pilgrimage manuals—relatively few have studied Arabic encyclopedism. Chapter 1, “Encyclopedism in the Mamluk Empire,” explores why al-Nuwayrī compiled his work. Muhanna offers a useful distinction be- tween “encyclopedism and encyclopedia” (pp. 11-13) and grounds his ap- proach in encyclopedism, which is the idea that there is a “spectrum…upon which we might situate a variety of works belonging to different premodern genres and possessing different principles of order, structure, focus, agen- da, audience, and modes of reading” (12). The merit of this approach is that it casts a wider, less restrictive net, since “reading these texts as tokens of a similar knowledge practice rather than members of a common genre per- mits us to see the continuities between strategies of knowledge-ordering that cut across different bibliographical categories” (12). Given the fluc- tuating and complex notions of genre—the genre of medieval Arabic and Persian tārīkh, for example, encompasses a heterogeneous variety of texts, from local histories, chronicles, biographical dictionaries, and often some combination of all of the above—encyclopedism is a compelling conceptual approach to this body of literatures. Muhanna argues that while al-Nuwayrī himself situated his work within the tradition of adab, his inspirations and sources belonged to other genres, which lead to the rise of this hybrid genre of encyclopedism. Al-Nuwayrī was an esteemed copyist who directly ad- dressed the scribal arts in The Ultimate Ambition, which “both described the expectations of the scribe and provided the content of his education: it styled itself as an encyclopedic guide for an encyclopedic education” (21). Chapter 2, “Structures of Knowledge,” offers a 30,000ft view of al-Nu- wayrī’s work, including its arrangement, structure, and overall composi- tion, and compares it to other Mamluk encyclopedic texts and to earlier adab works. This chapter is particularly useful to scholars who want an introduction into The Ultimate Ambition and Arabic encyclopedism, which Muhanna argues was itself a mélange of other extant genres: the work is “not recognizably a literary anthology, a cosmographical compendium, a chronicle, a pharmacopia, or a scribal manual, but an amalgam of all of these genres” (49). Chapter 3, “Sources of Knowledge,” contextualizes al-Nuwayrī’s com- pendium by situating it within the scholarly milieu of centers of learning within the Mamluk Empire, particularly Cairo and Damascus, during the thirteenth to fifteenth centuries. By situating al-Nuwayrī within the Nā- siriyya madrasa in Cairo and the intellectual, familial, and professional connections he cultivated and from which he benefitted, the author brings a granular depth to al-Nuwayrī and his work. This chapter is of particular interest to scholars of the production and circulation of knowledge. In Chapter 4, “Encyclopedism and Empire,” Muhanna turns to the im- perial and administrative scaffolding of the Mamluk Empire. The author argues that since compilers like al-Nuwayrī were part of the Mamluk bu- reaucracy, they “were particularly attuned to the processes of centralization and consolidation that transformed the politics of their time (4),” and wrote for an audience that reflected the nexus between literary encyclopedism and the imperial Mamluk state. Muhanna considers administrative knowl- edge and scholarly knowledge as separate but related spheres, arguing that “gathering vast quantities of information, collating sources, and synthe- sizing diverse types of knowledge represented the core activities of both the administrator and the large-scale compiler… a career in bureaucracy helped develop the skills of archiving and itemization that any compiler would have possessed…What set the two domains apart, however, was a difference in the types of knowledge that were valued. The world of admin- istration was one of contemporary, mutable information” (104). Muhanna’s more important argument in this chapter, however, is his claim about the unique position of Mamluk bureaucrats to be curators of knowledge and practices in the Mamluk Empire. He argues, “The common thread uniting the diverse professionals that comprised the administra- tion…was the importance attached to gathering data in the service of the state… By virtue of their access to demographic, financial, historical, and legal materials about the empire’s subjects, institutions, and communities, the bureaucratic class was in a unique position to shape the politics of their day in a manner that no other professional group could achieve” (104). As a bureaucrat-turned-scholar and an expert copyist, al-Nuwayrī embodied the related spheres of knowledge gathering, organization, and transmission in Mamluk Cairo. Chapter 5, “Working Methods,” delves into the manuscript tradition and reconstructs the composition history of al-Nuwayrī’s work. Muhanna addresses the strategies of collation, edition, and the management of sourc- es involved in the production of large compilations during the Mamluk period. The Chapter 6, “The Reception of the Ultimate Ambition,” addresses the literary afterlife of al-Nuwayrī’s work by discussing its reception in the Islamicate world and in Europe, with particular attention to the Dutch re- ception. By considering reception history of al-Nuwayrī’s work, Muhanna’s brief but engaging final chapter considers the impact of Mamluk encyclo- pedism in shaping the way Islamicate thought was perceived both within Europe and the Islamicate world. Muhanna’s appendices will prove valuable to scholars. “Appendix A: The Contents of the Ultimate Ambition” is extremely useful for those who do not share Muhanna’s patience to delve into the 31-volume work itself. In Appendix B, Muhanna compares the tables of contents of the two editions of The Ultimate Ambition: that of the standard Dar al-Kutub al-Misriyya edition, which was begun in 1923 but only completed in 1997, which is dif- ficult to access; and the more recent Dar al-Kutub al-‘Ilmiyya edition, pub- lished in Beirut in 2004, which is more widely available. The 11 figures that Muhanna intersperses throughout his book are attractive additions to his work, but it is the 13 tables that showcase Muhanna’s service to organize, divide, and categorize the sources, focusing primarily on al-Nuwayrī’s Ulti- mate Ambition itself. Some of these tables include: identifying The Ultimate Ambition’s chapter word counts for the Cairo and Beirut editions; outlining the arrangement of seven classical adab encyclopedias; and identifying and listing the sources of The Ultimate Ambition in its books 1, 3, and 4. These are valuable sources that the author has produced to help scholars and stu- dents make better sense and use of al-Nuwayrī’s massive tome. The World in a Book is a valuable contribution to studies in Arabic lit- erature, Mamluk history, and the production and circulation of knowledge in the medieval Islamicate world. Specialists will benefit most from this work, but its excellent readability makes it a valuable volume for graduate and undergraduate students as well as those interested in the production of knowledge in the Middle East more broadly. Mimi HanaokaAssociate Professor of Religious StudiesUniversity of Richmond

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Greco, Raffaella, Fabio Ciceri, Maddalena Noviello, Attilio Bondanza, Luca Vago, Giacomo Oliveira, Jacopo Peccatori, et al. "How to Monitor Immune Reconstitution Following Allogeneic Hematopoietic Stem Cell Transplantation: A Survey from the EBMT- Cellular Therapy & Immunobiology Working Party." Blood 128, no. 22 (December 2, 2016): 4581. http://dx.doi.org/10.1182/blood.v128.22.4581.4581.

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Abstract Background: Post transplant immune reconstitution plays a major role in determining the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT), and is currently monitored with different techniques in different Centers, with the aim of identifying clinically relevant immunological biomarkers. However, it is unclear which and how many of these immunological tests are currently performed on a routine basis, and which ones have the potential to predict patient outcome, and possibly guide patient care after allo-HSCT. Methods: The EBMT Cellular Therapy & Immunobiology Working Party (CTIWP) conducted a survey to identify current policies to monitor immune reconstitution in patients undergoing allo-HSCT and possibly reach a general consensus. This study followed the EBMT study guidelines. All EBMT Centers were invited to participate. Each participating Center received a questionnaire on the availability of specific immunomonitoring assays, specifying the use in clinical practice and/or within investigational trials. Assays were based on relatively simple and readily available parameters such as absolute lymphocyte counts (ALC) to more complex cellular and molecular tests. Moreover, the Centers were asked to define the transplant platform (HLA-identical sibling, matched unrelated donor, haploidentical and/or cord blood) on which each test is generally performed. Results: Policies for post-transplant immunomonitoring have been reported by 35 participating EBMT Centers active in 14 Countries and performing allo-HSCT from HLA identical related (35 centers), matched unrelated (33), haploidentical (34), unrelated cord blood (27). Complete blood counts and immunoglobulins are routinely tested for patients' care by all centers. Relative proportions of T cell subsets are currently tested by flow-cytometry as "standard of care" or "investigational" by 82% and 17% of centers respectively. B cell and NK cell counts are quantified routinely by 46% and 23% of Centers, and investigationally by 40% of Centers. The availability of molecular tests (STR, qPCR, Fish) to measure post-transplant engraftment are reported by all Centers, except two, as a standard of care measure. T cell receptor-expressing circles (TRECs) and/or K-deleting recombination excision circles (KRECs) are quantified within selected clinical trials by 37% of Centers. Interestingly, 60% of Centers evaluate, mostly as an investigational measure, antigen specific T cell responses by: proliferation assays (49%), interferon-gamma enzyme-linked immunospot-Elispot (49%), intracellular cytokine staining (46%) and tetramer/dextramer staining (37%). Most of these Centers test responses to Cytomegalovirus and Epstein Barr Virus, and 5 Centers use at least one of these assays on a routine basis. About half of the participating Centers (43%) commonly test antigen-specific antibodies, mainly as responses to vaccines, and not routinely. T-cell receptors (TCR) and B-cell receptors (BCR) repertoires are measured by spectratyping in 14 out of 35 Centers (4 as clinical practice and 10 in selected trials), or, in selected trials, by next generation sequencing (in 11 out of 35 the participating Centers). Conclusions: Results of this survey indicate that country- and center expertise are associated with heterogeneous and distinct protocols, and underline the clinical need to harmonize methods and to provide practical recommendations for monitoring post-transplant immune reconstitution, both for routine purposes and investigational studies. Adequate reporting and connection between individual Centers exploiting these data will foster collaborative and comparative research studies, with the ultimate goals of improving patient care and refining our understanding of the immunological correlates to clinical outcome. Acknowledgments: R. Ram, M. A. Diaz, G. McQuaker, D. Russo, E. Faber, P. Chiusolo, C. Rössig, S. M. Martin, A. Anagnostopoulos, M. Stelljes, K. Orchard, P. Jindra, A. Sampol, K. Patrick, M. A. Bekadja, J. Gayoso, A. Olivieri, J. Passweg, E. Jost, H Labussiere-Wallet, Y Koc, A. Lange, I. Garcia Cadenas, N. Kröger, A. Biondi, N. Milpied, D. Olive, E. Lanino, G. Stuhler, J.H. Dalle, J.R. Cabrera Marín, F. Ciceri, D. Uckan-Cetinkaya, R. Parody Porras, G. Kriván. Disclosures Ciceri: MolMed SpA: Consultancy. Bonini:TxCell: Membership on an entity's Board of Directors or advisory committees; Molmed SpA: Consultancy.

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Easton, Graham. "Books: Making a Medic: the Ultimate Guide to Medical School." British Journal of General Practice 70, no. 694 (April 30, 2020): 252. http://dx.doi.org/10.3399/bjgp20x709793.

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Lunn, Jeffrey J., and David O. Warner. "The Ultimate Guide to Finding the Right Job after Residency." Anesthesiology 105, no. 5 (November 1, 2006): 1066. http://dx.doi.org/10.1097/00000542-200611000-00040.

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Hejtmanek, Michael. "The Ultimate Guide to Finding the Right Job After Residency." Regional Anesthesia and Pain Medicine 31, no. 5 (September 2006): 477. http://dx.doi.org/10.1097/00115550-200609000-00015.

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Mullin, Nick. "The ultimate alphabet GP guide to unusual psychiatric disorders continued." Morecambe Bay Medical Journal 8, no. 5 (November 29, 2019): 144–50. http://dx.doi.org/10.48037/mbmj.v8i5.244.

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Schneider, Peter A. "Write to Sell: The Ultimate Guide to Great Copywriting20082Andy Maslen. Write to Sell: The Ultimate Guide to Great Copywriting. Marshall Cavendish Business, 192 pp. $16.95." Journal of Consumer Marketing 25, no. 2 (March 21, 2008): 132–33. http://dx.doi.org/10.1108/07363760810858873.

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Blazsek, Istvan, Estelle Oberlin, Michele Souyri, and Bruno Peault. "The Osteo-Hematon: Modeling the Ontogenic Development of Stem-Cell Niches into Discrete Organotypic Proliferative Units." Blood 104, no. 11 (November 16, 2004): 667. http://dx.doi.org/10.1182/blood.v104.11.667.667.

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Abstract Hemogenic stem cells (HSC) emerge at distinct allocation territories during ontogenesis. They irrigate freely the whole body by the blood stream, but the adult HSC expand and differentiate exclusively in the bone marrow (BM). This implies that stem cells are not autonomous units of development; rather, tissue specific niches control their destiny. We investigated the spatio-temporal emergence of stem cells and nest-forming cells, and basic mechanisms by which they shape together the functional-proliferative units in the liver and BM during ontogenesis. Video microscopy in gut/liver primordium cultures provided direct evidence for intrinsic emergence of a primitive vasculo-hemogenic meshwork guided by pulsative, cardiomyogenic cells around nascent hepatic cords in E8.75-E10 mouse embryos. Gain-of-competence and development of hepatic units required firm aggregation of cholangio-hepatic (CK19+/CK18+), hemogenic (CAFC) and vasculogenic stem/progenitor cells and nest-forming cells into compact 3-D structures, similarly to BM hematons. Colonization and expansion of HSC in the mouse liver at E12, then in the BM at postnatal d2, numerically correlated with the increase in isolatable niches/hematons. Time-lapse video microscopy, quantitative colony assays, FACS and immunocytochemistry analyses of the adult human BM showed that the hematon is enriched in mesenchymal stem cells, preadipocytes/adipocytes, contractile myogenic cells, a vascular meshwork, guardian macrophages and hemopoietic stem/progenitor cells (Sca-1/c-kit/CD34/Thy-1/CD31+). A hematon module plays the role of an organizing center that emits growth signalling factors and accumulates morphogen/differenciator factors, retinoids and 1,25-di(OH)-vitaminD3. The physical attachment of many hematons to spongy bone suggests that they form the basic structural-functional units in the ultimate, fully competent BM. We suggest designating these units osteo-hematons. A comparative analysis of BM aspirates from healthy donors (n=75) and patients (n=210) revealed the disorganization of osteo-hematon modules in AML prior to therapy and in CML during all stages of the disease.

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Ives, Jack D., and Peggy Wayburn. "Adventuring in Alaska: The Ultimate Travel Guide to the Great Land." Mountain Research and Development 14, no. 3 (August 1994): 270. http://dx.doi.org/10.2307/3673781.

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Quist, Ned, and James R. Campbell. "Festival Fever: The Ultimate Guide to Musical Celebrations in the Northeast." Notes 54, no. 2 (December 1997): 466. http://dx.doi.org/10.2307/899529.

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Journal articles on the topic 'The Ultimate Guide to E.D'

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