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Relevant bibliographies by topics / Therapeutic enzymes

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Academic literature on the topic 'Therapeutic enzymes'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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Journal articles on the topic "Therapeutic enzymes"

1

Städler, Brigitte, and Alexander N. Zelikin. "Enzyme prodrug therapies and therapeutic enzymes." Advanced Drug Delivery Reviews 118 (September 2017): 1. http://dx.doi.org/10.1016/j.addr.2017.10.006.

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Zhu, Chen-Yuan, Fei-Long Li, Ye-Wang Zhang, Rahul K. Gupta, Sanjay K. S. Patel, and Jung-Kul Lee. "Recent Strategies for the Immobilization of Therapeutic Enzymes." Polymers 14, no. 7 (2022): 1409. http://dx.doi.org/10.3390/polym14071409.

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Therapeutic enzymes play important roles in modern medicine due to their high affinity and specificity. However, it is very expensive to use them in clinical medicine because of their low stability and bioavailability. To improve the stability and effectiveness of therapeutic enzymes, immobilization techniques have been employed to enhance the applications of therapeutic enzymes in the past few years. Reported immobilization techniques include entrapment, adsorption, and covalent attachment. In addition, protein engineering is often used to improve enzyme properties; however, all methods prese

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Noten, J. B. G. M., W. M. A. Verhoeven, S. Tuinier, and D. Touw. "Therapeutic drug monitoring." Acta Neuropsychiatrica 11, no. 1 (1999): 15–16. http://dx.doi.org/10.1017/s0924270800036309.

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SUMMARYThe cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, including psychotropics. Its activity is determined by both genetic and environmental factors. The most important iso-enzymes for psychiatry in general are P450 IID6, 3A4 and 1A2. Knowledge about the involvement of these enzymes and biotransformation processes is mandatory because of the individual variability in their metabolic capacity. Regular measurement of plasmaconcentrations of (psycho)pharmacological compounds is therefore essential. In addition, the potential value of pheno- and/or ge

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Bax, Bridget E. "Erythrocytes as Carriers of Therapeutic Enzymes." Pharmaceutics 12, no. 5 (2020): 435. http://dx.doi.org/10.3390/pharmaceutics12050435.

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Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to induce an advantageous physiological change. However, the metabolic and clinical efficacies of parenterally or intramuscularly administered therapeutic enzymes are very often limited by short circulatory half-lives and hypersensitive and immunogenic reactions. Over the past five decades, the erythrocyte carrier has been extensively studied as a s

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Dahikar, S. B., and S. A. Bhutada. "DNA Repair Enzymes as Therapeutic Agents: a Review." Mikrobiolohichnyi Zhurnal 84, no. 1 (2021): 65–71. http://dx.doi.org/10.15407/microbiolj84.01.065.

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DNA damage is long recognized factor for development and progression of cancer in humans. Genome instability is the leading factor behind development of cancer. There are some DNA repair pathways and DNA damage checkpoints present in all creatures, without them the functional stability gets compromised. Impaired DNA repair results in genomic instability leading to development of cancer, limited lifespan, early ageing. UV rays and Ionizing radiations are the major exogenous forces responsible for DNA damage, causing lesions in DNA. These lesions are cause of photoageing. Protection administered

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Amber, S. Gad. "Some Important Therapeutic Enzymes and their Uses." Chemistry Research Journal 5, no. 3 (2020): 165–72. https://doi.org/10.5281/zenodo.12589362.

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<strong>Abstract </strong>Enzymes are protein molecules that are responsible for many vital reactions including digesting food, building bones, purifying blood and detoxification. Enzymes also, have several clinical uses in treatments including leukemia, metabolic disorders, inflammation, cardiovascular disease and lysosomal storage diseases etc. Specificity, stability, and substrate conversion makes therapeutic enzymes advisable agents more than non-enzymatic drugs. As foreign proteins to the body, enzymes are representing antigenicity that can induce immune response which lead to immuno

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Zbar, Nedhaal Suhail. "A Review Article: Protein Engineering of Therapeutic Enzymes." International Journal for Research in Applied Sciences and Biotechnology 9, no. 1 (2022): 140–51. http://dx.doi.org/10.31033/ijrasb.9.1.16.

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Through the development of advanced, stimulus-responsive pharmacological systems, protein engineering has the potential to alter the metabolic drug landscapes. Protein therapies are a fast growing category of FDA-approved medications that have the potential to improve clinical consequences in the long run. Protein therapeutics engineering is still in its preliminary phase; however recent advancements in protein engineering skills are being used to gain direct monitoring over pharmacodynamics. Drugs that are intended to be metabolized under specific conditions are known as stimulus-responsive p

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Wiederschain, G. Ya, and M. Baldry. "Directory of therapeutic enzymes." Biochemistry (Moscow) 71, no. 11 (2006): 1289–90. http://dx.doi.org/10.1134/s0006297906110162.

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Alisi, Anna, Sara Tomaselli, Clara Balsano, and Angela Gallo. "Hepatitis C virus therapeutics: Editing enzymes promising therapeutic targets?" Hepatology 54, no. 2 (2011): 742. http://dx.doi.org/10.1002/hep.24409.

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Sioud, Mouldy, and Marianne Leirdal. "Therapeutic RNA and DNA enzymes." Biochemical Pharmacology 60, no. 8 (2000): 1023–26. http://dx.doi.org/10.1016/s0006-2952(00)00395-6.

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Dissertations / Theses on the topic "Therapeutic enzymes"

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Gordon, Nathaniel Charles. "Protease engineering for therapeutic applications." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648185.

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Vigne, Aurélie. "Microfluidic tools for the engineering of enzymes of therapeutic interest." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0391/document.

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Cette thèse concerne le développement d’outils microfluidique pour l’ingénierie d’enzymes d’intérêt thérapeutique. La microfluidique à base de gouttelettes présente un énorme potentiel dans le domaine de la biologie quantitative. Nous développons des outils microfluidiques pour l’évolution dirigée de l’enzyme L-asparaginase, enzyme utilisée comme traitement de laleucémie lymphoblastique aiguë. Ce traitement est basée sur une enzyme d’origine bactérienne,ce qui conduit à déclencher des réactions immunitaires qui se traduit par l’interruption du traitement, souvent fatale pour le patient. Cepend

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Lovering, Andrew Lee. "X-ray crystallographic studies of therapeutic enzymes : nitroreductase and AKR1C3." Thesis, University of Birmingham, 2003. http://etheses.bham.ac.uk//id/eprint/3588/.

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The \(Escherichia\) \(coli\) enzyme nitroreductase has been proposed as a candidate for the Gene-Directed Enzyme Prodrug Therapy approach in treating cancer. Structural studies on the enzyme were instigated in a first step towards improving enzyme activity. The enzyme was crystallized with the substrate analogue, nicotinic acid, and the structures of three crystal forms obtained. The fold has a mixed a/P structure, with a molecule of nicotinic acid bound next to the FMN cofactor. Several active site residues were identified as candidates for mutation. This procedure produced many mutant enzyme

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Guiney, Daniel. "Design and synthesis of inhibitors of enzymes in the folate biosynthesis pathway." Thesis, University of Strathclyde, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273387.

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Hart, R. J. "Developing protein conjugation techniques to enhance cell delivery of therapeutic enzymes." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/18996/.

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The focus of disease research often surrounds therapeutic pathway identification and the subsequent investigation of proteins or compounds that potentially interfere with disease mechanisms. However, finding targets and effective therapeutic domains often overshadows another important aspect of drug delivery and efficacy; the method of domain conjugation. Unfortunately the combination of good therapeutic components and good therapeutic design can often be amiss, with differing skills and groups needed to marry the two together. In recognition of this, there are new techniques emerging that aim

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Maheshwari, Sweta. "Caractérisation biochimique et cellulaire des enzymes clés du métabolisme des phospholipides chez Plasmodium falciparum." Thesis, Montpellier 2, 2012. http://www.theses.fr/2012MON20004.

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Le développement du parasite Plasmodium falciparum, responsable du paludisme, nécessite la synthèse de phospholipides et plus particulièrement de phosphatidylcholine (PC) et phosphaditylethanolamine (PE) qui représentent environ 85% de la totalité des phospholidipes du parasite. Leur synthèse s'effectue principalement par les voies métaboliques de novo, voies de Kennedy, en trois étapes enzymatiques. Les enzymes CTP: phosphoethanolamine cytidylyltransferase (ECT) et CTP: phosphocholine cytidylyltransferase (CCT) catalysent les étapes limitantes des deux voies de biosynthèse de la PE et de la P

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Mao, Wei. "Etude biochimique et sélection d'inhibiteurs spécifiques d'une cible thérapeutique leishmanienne : la GDP-Mannose-Pyrophosphorylase." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS481.

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Les leishmanioses sont des maladies tropicales négligées provoquées par un protozoaire parasite du genre Leishmania, et transmises par un insecte vecteur, le phlébotome. Les leishmanioses menacent 310 millions de personnes dans 98 pays à travers le monde. Les traitements antileishmaniens actuels sont limités et présentent des problèmes majeurs de toxicité et d'émergence de chimiorésistance. Dans ce contexte, il est nécessaire de développer de nouveaux agents antileishmaniens spécifiquement dirigés contre une cible thérapeutique chez le parasite. La GDP-Mannose Pyrophosphorylase (GDP-MP) est un

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AIELLO, ROSANNA GILDA. "IMPROVING THE THERAPEUTIC POTENTIAL OF LYSOSOMAL ENZYMES TO TREAT CNS IN LYSOSOMAL STORAGE DISORDERS." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/793420.

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Lysosomal storage disorders (LSD) are a large group of inherited genetic diseases caused by impaired activity of lysosomal enzymes leading to accumulation of undigested macromolecules within the lysosomes and thus cell dysfunction. The clinical manifestation is heterogeneous and neurological involvement represents a major problem. The correction of the defective gene/protein represents the primary strategy for the treatment of these genetic conditions. However, the clinical translation of these approaches is very challenging because of the difficulty in achieving and maintaining therapeutic

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Mendieta, Martínez Laura. "Protease inhibitors as therapeutic agents." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/279388.

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Proteases are involved in a high number of diseases, and thus, are relevant targets. For that reason our main goal was the discovery of protease inhibitors as therapeutic agents. We focused our study in four proteases: dipeptidyl peptidase IV (diabetes mellitus type 2), prolyl oligopeptidase (cognitive disorders) and cathepsins L and B (cancer).For the discovery of inhibitors, three strategies were selected: medicinal plant screening, high throughput screening and the characterization of a combinatorial chemistry library. Once accomplished the DPP IV recombinant expression optimization, t

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Mirza, Ahmad. "Structural characterization of novel antimicrobial therapeutic targets and crystallographic examination of enzymes involved in xenobiotic metabolism." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86555.

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Part I. Recently there has been an alarming rise in the number of infections due to pathogenic organisms that are insensitive to our current arsenal of pharmaceuticals, necessitating the identification of new antimicrobial targets. Here, we describe structural studies of two enzymes from the aspartate family of biosynthetic enzymes in order to assess their potential for drug targeting. Our first report details how an unlikely inhibitor with low millimolar binding characteristics, 5-hydroxy-4-oxo-norvaline, can effectively inactivate homoserine dehydrogenase (HSD) through the formation of a tig

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Books on the topic "Therapeutic enzymes"

1

Cichoke, Anthony J. Enzymes, nature's energizer. Keats Pub., 1997.

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Labrou, Nikolaos, ed. Therapeutic Enzymes: Function and Clinical Implications. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7709-9.

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Lee, Lita. The enzyme cure: How plant enzymes can help you relieve 36 health problems. Future Medicine Pub., 1998.

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Cichoke, Anthony J. Enzymes the sparks of life. Books Alive, 2008.

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DeFelice, Karen L. Enzymes : go with your gut: More practical guidelines for digestive enzymes. ThunderSnow Interactive, 2006.

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Cichoke, Anthony J. Enzymes and enzyme therapy: How to jump start your way to lifelong good health. Keats Pub., 1994.

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Albert, Lauwers, and Scharpé Simon 1944-, eds. Pharmaceutical enzymes. Marcel Dekker, 1997.

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Howell, Edward. Food enzymes for health and longevity. 2nd ed. Lotus Press, 1994.

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Howell, Edward. Enzyme nutrition: The food enzyme concept. Avery, 1985.

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Bickerstaff, Gordon F. Enzymes in industry and medicine. E. Arnold, 1987.

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Book chapters on the topic "Therapeutic enzymes"

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Nampoothiri, K. Madhavan, Abdulhameed Sabu, and Ashok Pandey. "Therapeutic Enzymes." In Enzyme Technology. Springer New York, 2006. http://dx.doi.org/10.1007/978-0-387-35141-4_35.

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Kumar, Swaroop S., and Sabu Abdulhameed. "Therapeutic Enzymes." In Bioresources and Bioprocess in Biotechnology. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4284-3_2.

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Syldatk, Christoph. "Therapeutic Enzymes." In Introduction to Enzyme Technology. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-42999-6_19.

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Lutz, Stefan, Elsie Williams, and Pravin Muthu. "Engineering Therapeutic Enzymes." In Directed Enzyme Evolution: Advances and Applications. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50413-1_2.

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Torchilin, Vladimir P. "Immobilization of Therapeutic Enzymes." In Progress in Clinical Biochemistry and Medicine. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75821-8_3.

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Pişkin, A. Kevser. "Therapeutic Potential of Immobilized Enzymes." In Uses of Immobilized Biological Compounds. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1932-0_15.

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Ambika, Lakshmi Kesari. "Therapeutic Applications of Microbial Enzymes." In Microbial Enzymes as Potential Biotherapeutics in Human Healthcare. CRC Press, 2025. https://doi.org/10.1201/9781003473008-2.

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Silva, Ana Catarina, Cládia Pina Costa, Hugo Almeida, João Nuno Moreira, and José Manuel Sousa Lobo. "Hormones, Blood Products, and Therapeutic Enzymes." In Current Applications of Pharmaceutical Biotechnology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/10_2019_111.

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Taipa, M. Ângela, Pedro Fernandes, and Carla C. C. R. de Carvalho. "Production and Purification of Therapeutic Enzymes." In Advances in Experimental Medicine and Biology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7709-9_1.

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Torchilin, Vladimir P. "Therapeutic Immobilized Enzymes for Parenteral Application." In Progress in Clinical Biochemistry and Medicine. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75821-8_4.

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Conference papers on the topic "Therapeutic enzymes"

1

Mannervik, Bengt. "Therapeutic GST enzymes targeting cancer via epitope-binding fusion proteins." In International Conference on Cell Science and Regenerative Medicine. United Research Forum, 2024. https://doi.org/10.51219/urforum.2024.bengt-mannervik.

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O’Toole, S., H. Melarcode, S. Elbaruni, et al. "EP926 PAD enzymes as a candidate therapeutic target in ovarian cancer." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.972.

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Ravi, Vidhya Shree, Abigail J. Clevenger, Sam Morganti, Shreya A. Raghavan, and Alex J. Walsh. "Unveiling the Metabolic Diversity in Cancer: Quantifying Cancer Stem Cells and Bulk Cancer Cells Through FLIM Imaging and Computational Analysis." In Clinical and Translational Biophotonics. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/translational.2024.tw1b.2.

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This study tests the hypothesis that Fluorescence Lifetime Imaging Microscopy (FLIM) of the endogenous metabolic co-enzymes (nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FAD)) provides insights into the metabolic signatures of CSCs and bulk tumor cells. By identifying and quantifying metabolic differences, researchers can potentially develop tailored therapies that address both CSCs and bulk tumor cells, improving therapeutic outcomes and addressing the challenges posed by tumor heterogeneity.

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Bradic, Jovana V., Anica M. Petrovic, and Vladimir Lj Jakovljevic. "Can a three-week administration of methanol extract of wild garlic modulate systemic redox state in hypertensive rats?" In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.575b.

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Wild garlic (Allium ursinum) is a widespread perennial herbaceous plant that has wide therapeutic applications and it is used as well as food. Natural preparations based on wild garlic have been used for gastrointestinal tract disorders, as antioxidants, antihypertensive, hypolipidemic agents, etc. Nevertheless, the data related to the effects of chronic wild garlic extract consumption on systemic redox state in hypertensive animals is yet to be understood. Therefore, the main goal of this study was to examine the effects of a three-week application of ethanolic extract from wild garlic on oxi

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L.A., Bugaev, Voikina A.V., Morozova M.A., and Maltsev V.N. "APPROACHES TO DETERMINING THE WELL-BEING OF MARICULTURAL OYSTER FARMS." In II INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE "DEVELOPMENT AND MODERN PROBLEMS OF AQUACULTURE" ("AQUACULTURE 2022" CONFERENCE). DSTU-Print, 2022. http://dx.doi.org/10.23947/aquaculture.2022.32-36.

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The paper presents the results of studies of the parasitological, infectious and biochemical status of the giant oyster (Crassostrea gigas) from the Black Sea mariculture farms. The studies were carried out in May and August 2020. The occurrence of pathogens of clionosis, polydorosis, hexamitosis in oysters grown in the Black Sea was revealed. Vibrios Vibrio pomeroyi, V. gigantis, V. pacinii, V. harveyi, V. alginolyticus, V. fortis were isolated among the causative agents of infectious diseases of molluscs, of which Vibrio pomeroyi, V. alginolyticus were recognized as pathogenic for Crassostre

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Vazquez, Louis C., Erik Hagel, Bradley J. Willenberg, Christopher D. Batich, and Malisa Sarntinoranont. "Effect of Polymer Coated Needles on Infusate Backflow During Convection-Enhanced Delivery." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19557.

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Currently, many central nervous system disorders cannot be treated effectively using conventional drug delivery methods such as oral and intravenous drug administration. Therapeutic agents for such disorders often contain polar proteins with high molecular weight compounds (i.e. enzymes, antibodies and gene vectors) that are too large to diffuse through the tight junctions of the blood brain barrier (BBB) [1]. Moreover, it has been shown that low molecular weight compounds, though highly diffusive within brain tissue and tumors, have a limited distribution of just a few millimeters from the si

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Gabrielli, Ângelo, Camila Sousa Bragunce Alves, Bruna Oliveira Bicalho, and Débora Pimenta Alves. "Benefits and Challenges of Cannabis Use in the Treatment of Refractory Epilepsy." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.239.

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Introduction: Refractory epilepsy (RE) is a disease that causes continuous and debilitating seizures. Due to the ineffectiveness of antiepileptic therapies, there is a growing interest in drugs made with cannabidiol (CBD), a substance extracted from Cannabis. Objective: To point out benefits and challenges of the use of CBD in the treatment of RE. Methods: Literature review performed at PubMed, with the descriptors Epilepsy, Drug Therapy and Cannabis. Results: It is suggested that CBD is mediated by cannabinoid receptors coupled to protein G, by blockade of NMDA receptors, by GABAergic modulat

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Ofosu, F. A., G. J. Modi, M. R. Buchanan, J. Hirsh, and M. A. Blajchman. "HEPARIN IS NOT AN EFFICIENT INHIBITOR OF THE FACTOR Xa-DEPENDENT ACTIVATION OF FACTOR V AND FACTOR VIII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642931.

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We have previously proposed that the steps in coagulation most sensitive to inhibition by heparin are the thrombin-dependent activation of factor V and factor VIII. This observation was based on the demonstration that therapeutic concentrations of heparin or 1μM of the thrombin specific inhibitor, phe-pro-arg CH2Cl (PPACK) completely inhibited the activation of prothrombin when contact-activated plasma (CAP) was recalcified for up to 1 min. Under similar conditions, heparin and PPACK only partially inhibited the activation of factor X. Moreover, the addition of thrombin (lOnM) to CAP 1 min bef

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Oliveira, Marco Antônio Rodrigues Gomes de, and Isaura Maria Mesquita Prado. "Evidence and affects in Duchenne muscular dystrophy in children and Golden Retriever dogs." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.302.

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Introduction: Progressive muscular dystrophies differ in different ways due to their age of manifestation, the distribution of muscle weakness and the association of heart, central nervous system and peripheral nervous system. The most severe and common form of muscular dystrophies is Duchenne muscular dystrophy (DMD). Its involvement is 1/3500 male babies born alive and is attributed to 80% of cases of dystrophinopathies. The impairment of the dystrophin-glycoprotein complex in Becker and Duchenne dystrophies, in most congenital and girdle dystrophies, destruction of the sarcolemmal muscle fi

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Turina, E. L., S. G. Efimenko, Yu A. Kornev та A. P. Liksutina. "Results of Сamelina oil assessment". У РАЦИОНАЛЬНОЕ ИСПОЛЬЗОВАНИЕ ПРИРОДНЫХ РЕСУРСОВ В АГРОЦЕНОЗАХ. Federal State Budget Scientific Institution “Research Institute of Agriculture of Crimea”, 2020. http://dx.doi.org/10.33952/2542-0720-15.05.2020.35.

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Camelina sativa (L.) Crantz – is an annual oilseed crop in the family Brassicaceae. The aim of the research was to study oil obtained from camelina seeds cultivated in the Crimea. Determination of fatty acid composition was carried out on the gas chromatograph “Хроматэк – Кристалл 5000” (Hromatek - Crystal 5000); automatic dosing unit ДАЖ-2М (DAJ- 2M); capillary column SolGelWax 30m × 0.25 mm × 0.5 μm; carrier gas – helium; speed – 22 centimeters per second; programming temperature –178–230 °С. The preparation of fatty acid methyl esters (FAMEs) using gas-liquid chromatography (GC) was perform

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Reports on the topic "Therapeutic enzymes"

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Sukenik, Assaf, Paul Roessler, and John Ohlrogge. Biochemical and Physiological Regulation of Lipid Synthesis in Unicellular Algae with Special Emphasis on W-3 Very Long Chain Lipids. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604932.bard.

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Various unicellular algae produce omega-3 (w3) very-long-chain polyunsaturated fatty acids (VLC-PUFA), which are rarely found in higher plants. In this research and other studies from our laboratories, it has been demonstrated that the marine unicellular alga Nannochloropsis (Eustigmatophyceae) can be used as a reliable and high quality source for the w3 VLC-PUFA eicosapentaenoic acid (EPA). This alga is widely used in mariculture systems as the primary component of the artificial food chain in fish larvae production, mainly due to its high EPA content. Furthermore, w3 fatty acids are essentia

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Chen, Shuo. Anti-Androgen Receptor RNA Enzyme as a Novel Therapeutic Agent for Prostate Cancer In Vivo. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada462865.

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Avihingsanon, Yingyos, Jongkonnee Wongpiyabovorn, and Nattiya Hirankarn. Biomarker discovery in systemic lupus erythematosus: genome-methylation approaches : Research report. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.15.

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Discovery of novel biomarkers in lupus nephritis Biomarkers are needed for making diagnosis and prognosis. In lupus nephritis, conventional tests like urinalysis or serum creatinine remain inadequate for patient care. In this proposal, we focused on non-invasive tools like blood and urine mRNAs or proteins. We chose candidate genes involving regulatory T-cell, B-lymphocyte signatures or vascular protective factors. Expression of regulatory cell signature (FOXP3) in peripheral blood mononuclear cells is associated with activity of lupus nephritis. We found FOXP3 mRNA levels in PBMCs from patien

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