Relevant bibliographies by topics / Therapeutic potential etc

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Therapeutic potential etc'

Author: Grafiati
Published: 5 June 2025
Last updated: 16 July 2025

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Journal articles on the topic "Therapeutic potential etc"

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Sorokin, O., S. Zinatulin, A. Kozlova, and M. Subotyalov. "BIOLOGICAL ACTIVITY AND THERAPEUTIC POTENTIAL OF METABIOTICS." Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry 11, no. 2 (2025): 224–36. https://doi.org/10.29039/2413-1725-2025-11-2-224-236.

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he human body is closely connected to the microflora through thousands of biologically active low molecular weight compounds. In the last decade, the idea has spread that in order to maintain and restore the microecology of the human body, not only live bacteria should be used, but also products of bacterial lysis and filtered products of their metabolism. Such low molecular weight microbial components are called metabiotics. According to their functional characteristics, metabiotics can be divided into the following large groups: 1) active metabolites (branched and unbranched short-chain fatt
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Goel, Rajeev, Tushar Saini, and Binny Mahendru. "Therapeutic potential of seaweeds." International Journal of Basic & Clinical Pharmacology 10, no. 5 (2021): 591. http://dx.doi.org/10.18203/2319-2003.ijbcp20211660.

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Seaweeds in general are known to contribute to the maintenance of health through their nutritional and medicinal properties and are served in soups and salads, cooked with grains, legumes or miso-soup broth, vegetable pies, stews and even consumed dried. The medicinal properties of seaweeds or vegetables have long been known in many cultures of people particularly those living in the coastal regions who are consuming these from centuries. Traditional Chinese dietotherapy (TCD) makes good use of natural marine nutrients and food to preserve health. Koreans wrap their bodies in seaweeds to get r
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Deoyani, Patil* Dilip Ahire. "Phytochemicals in Funaria Sp.: A Correlative Analysis for Therapeutic Potential." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 1129–33. https://doi.org/10.5281/zenodo.15606304.

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Since ancient times, bryophytes have been used in Indian traditional medicine to treat burns, bronchitis, tonsillitis, tympanitis, skin disorders, and cardiovascular problems. Funaria samples were collected from the Gautala Wildlife Sanctuary's Jalgaon region. This study examines the quantitative efficacy of phytochemicals. The Shapiro-Wilk test was used to determine whether the data had a normal distribution. The significance level for all statistical tests was set at 5% (α = 0.05). Using Pearson correlation analysis, the concentrations of phytochemicals and their order are strongly pos
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Salehi, Bahare, Alessandro Venditti, Mehdi Sharifi-Rad, et al. "The Therapeutic Potential of Apigenin." International Journal of Molecular Sciences 20, no. 6 (2019): 1305. http://dx.doi.org/10.3390/ijms20061305.

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Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases. The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin. The present work is an updated overview of apigenin, focusing on its health-promoting effects/therapeutic functions and, in particular, results of in vivo research. In addition to an introduction to its chemistry, nutraceutical features have also been described. The main key findings from in vivo research, including animal models and human
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Alam, Jahangir, and Lalit Sharma. "Potential Enzymatic Targets in Alzheimer’s: A Comprehensive Review." Current Drug Targets 20, no. 3 (2019): 316–39. http://dx.doi.org/10.2174/1389450119666180820104723.

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Alzheimer’s, a degenerative cause of the brain cells, is called as a progressive neurodegenerative disease and appears to have a heterogeneous etiology with main emphasis on amyloid-cascade and hyperphosphorylated tau-cascade hypotheses, that are directly linked with macromolecules called enzymes such as β- & γ-secretases, colinesterases, transglutaminases, and glycogen synthase kinase (GSK-3), cyclin-dependent kinase (cdk-5), microtubule affinity-regulating kinase (MARK). The catalytic activity of the above enzymes is the result of cognitive deficits, memory impairment a
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Govindaraj, Jayamathi. "A review on the therapeutic potential of Banana flower." Bioinformation 18, no. 4 (2022): 349–53. http://dx.doi.org/10.6026/97320630018349.

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Banana (Musa paradisiaca) flower is rich in phytochemicals and exhibit antioxidant, anti-inflammatory, anticancer properties etc. The flower extract of banana showed promising therapeutic effects due to the presence of phytochemicals and minerals.
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Vivek, Waghere* Raj Pawar Pranit Nimse Tejaswini Asawe. "A Review on Semecarpus Anacardium: Pharmacological Properties, Therapeutic Potential, And Traditional Uses." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 2753–66. https://doi.org/10.5281/zenodo.15267525.

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Bhallataka ( semecarpus anacardium), Commenly known as the marking nut. It belongs from family anacardeaceae  It contains phytoconstituent like urishinol ,bhilwanol, bioflavonoids, phenolic compounds etc. It shows various activity, like anti- inflammatory, hair growth promoter, anti-microbial, anti-cancer etc. It was plant used in ancient time to wound healing and prevent from water absorption in wound, also used to prevent from septic. But some toxic effect also shows like allergy symptoms etc. So, most people are leave to use of bhallataka (semecarpus anacardium linn). Their different p
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Dighe, Shantanu U., R. S. Jadhav, and D. N. Vikhe. "Biological Potential of Tribulus terrestris." Journal of Drug Delivery and Therapeutics 10, no. 3 (2020): 262–64. http://dx.doi.org/10.22270/jddt.v10i3.3982.

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Plants have a significant role in preserving human health and improving quality of life. gokshura (Tribulus terrestris Linn.) one of such plants, is mentioned in Ayurvedic texts for various therapeutic properties like balya(strengthening), brimhana (nutritive), rasayana(rejuvenator), mootrala(diuretic), shothahara(anti-inflammatory), vajikarana (aphrodisiac) etc. and useful in the management of mutrakrichhra (dysurea), ashmari (renal calculi) etc. It is a perennial plant, grown predominantly in India and Africa. Its extract contains alkaloids, saponins, resins, flavanoids and nitrates. As its
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Alven, Sibusiso, and Blessing A. Aderibigbe. "Hyaluronic Acid-Based Scaffolds as Potential Bioactive Wound Dressings." Polymers 13, no. 13 (2021): 2102. http://dx.doi.org/10.3390/polym13132102.

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The negative factors that result in delayed and prolonged wound healing process include microbial pathogens, excess wound exudates, underlying conditions, smoking, obesity, etc. Most of the currently used wound dressings demonstrate an inadequate capacity to treat wounds resulting from the factors mentioned above. The commonly used wound dressings include hydrogels, films, hydrocolloids, foams, fibers, sponges, dermal patches, bandages, etc. These wound dressings can be loaded with various types of bioactive agents (e.g., antibiotics, nanoparticles, anti-inflammatory drugs, etc.) to improve th
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Hasan, Mahbub, Nidhan Chandra Paul, Shamrat Kumar Paul, et al. "Natural Product-Based Potential Therapeutic Interventions of Pulmonary Fibrosis." Molecules 27, no. 5 (2022): 1481. http://dx.doi.org/10.3390/molecules27051481.

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Pulmonary fibrosis (PF) is a disease-refractive lung condition with an increased rate of mortality. The potential factors causing PF include viral infections, radiation exposure, and toxic airborne chemicals. Idiopathic PF (IPF) is related to pneumonia affecting the elderly and is characterized by recurring scar formation in the lungs. An impaired wound healing process, defined by the dysregulated aggregation of extracellular matrix components, triggers fibrotic scar formation in the lungs. The potential pathogenesis includes oxidative stress, altered cell signaling, inflammation, etc. Ninteda
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Dissertations / Theses on the topic "Therapeutic potential etc"

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Christian, Michael. "Exploring MDMA and its therapeutic potential." Honors in the Major Thesis, University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/672.

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The clinical application of MDMA has long been an issue of great interest for doctors, counselors, researchers, and users alike. Originally synthesized by a pharmaceutical company and subsequently tested on military personnel, the drug was then used by many clinicians and physicians prior to the DEA's strict regulation of the drug, which began in the mid 1980s (Mithoefer et al, 2010). The DEA has classified MDMA a "Schedule 1" drug, which means that it among the most controlled substances, a fact which has hindered the progress of research. For a detailed explanation of the DEA's scheduling of
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Turner, Katherine Ann. "Therapeutic Potential of rhTRAIL for Malignant Melanoma." Cleveland State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=csu1493983803123051.

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Allsbrook, Matthew. "TRIPTOLIDE IS A POTENTIAL THERAPEUTIC AGENT FOR ALZHEIMER’S DISEASE." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1858.

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Mounting evidence indicates an involvement of inflammation in the pathogenesis of Alzheimer’s disease. While there are other mechanisms involved, it is this role of inflammatory processes that we wish to investigate. Triptolide is the major constituent in the Chinese herb, Tripterygium wilfordii Hook F, and has been used for centuries as part of Chinese herbal medicine. The four ringed structure has close homology to drugs of the steroid class and it has been shown to be beneficial as an anti-inflammatory for rheumatoid arthritis and for treatment of certain cancers. The aim of this stud
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Nikolic, William Veljko. "Immunomodulation As A Potential Therapeutic Approach For Alzheimer’s Disease." Scholar Commons, 2008. https://scholarcommons.usf.edu/etd/429.

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Alzheimer's disease (AD) is the most prevalent form of progressive dementia and is characterized by the accumulation of amyloid beta (Aß) peptide in the brain and in the cerebral vessels forming cerebral amyloid angiopathy (CAA). As previously reported, an active immunization strategy of mice with Aß1-42 peptide results in decreased Th1 and increased Th2 cytokine responses as well as an effectively clearance of CNS Aß. This approach has also yielded favorable results for many patients, unfortunately, a small percentage of these study participants developed severe aseptic meningoencephalitis li
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Chuang, Hsiao-Ching. "Mechanistic Validation of Potential Anti-Breast Cancer Therapeutics." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1338213365.

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Hu, Di. "Targeting mitochondria as a potential therapeutic strategy in neurodegenerative disease." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1559999737544078.

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Masvekar, Ruturaj. "HIV AND OPIATES-MEDIATED NEUROTOXICITY: GSK3β IS A POTENTIAL THERAPEUTIC TARGET". VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3496.

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HIV-1 enters the CNS soon after initial systemic infection. HIV-1 can induce a wide range of neurological deficits, collectively known as HIV-1-associated neurocognitive disorders (HAND). Mature neurons are not infected by HIV-1; instead, infected and/or activated glial cells release various viral and cellular factors that induce direct and/or indirect neuronal toxicity, leading to HAND. Injection drug abuse is a significant risk factor for HIV-infection, and opiate drug abusers show increased HIV-neuropathology, even with anti-retroviral treatments. Our previous work has largely modeled HIV-n
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Nikolic, William Veljko. "Immunomodulation as a potential therapeutic approach for Alzheimer's disease." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002539.

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VanGundy, Zachary Curtis. "Differentiation of regulatory myeloid cells and the potential for therapeutic applications." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1405961624.

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Merchand, Reyes Giovanna. "Targeting myeloid cells as a potential Chronic Lymphocytic Leukemia therapeutic strategy." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595259890785332.

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Books on the topic "Therapeutic potential etc"

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Yoseph, Bar-Cohen, ed. Electroactive polymer (EAP) actuators as artificial muscles: Reality, potential, and challenges. 2nd ed. SPIE Press, 2004.

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Vorel, Stanislav R., and Sarah H. Lisanby. Therapeutic potential of TMS-induced plasticity in the prefrontal cortex. Edited by Charles M. Epstein, Eric M. Wassermann, and Ulf Ziemann. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780198568926.013.0038.

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This article discusses synaptic plasticity as a potential mechanism of enduring changes in function observed after relatively brief periods of repetitive (r)TMS. Plasticity is a use dependent enduring change in neural structure and function. The characteristics of plasticity are described in this article. Taking into account, the interactions between rTMS and pharmacological manipulations, this article explores how principles of synaptic plasticity may be exploited in the rational design of future rTMS paradigms in psychiatric disorders like major depressive disorder, obsessive-compulsive diso
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Potenza, Marc N., Kyle A. Faust, and David Faust, eds. The Oxford Handbook of Digital Technologies and Mental Health. Oxford University Press, 2020. http://dx.doi.org/10.1093/oxfordhb/9780190218058.001.0001.

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This book provides an academically oriented and scientifically based description of how technological advances may have contributed to a wide range of mental health outcomes, covering the spectrum from problems and maladies to improved and expanded healthcare services. Digital technologies covered include internet use (including social networking, shopping, gambling, viewing of pornography, etc.), digital gaming, smartphones, mobile applications, virtual reality, and computer-based therapeutic interventions. Both the positive and negative aspects of these various types of digital technologies
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Therapeutic and prophetic narratives in worship: A hermeneutic study of testimonies and visions : their potential significance for Christian worship and secular society. Verlag P. Lang, 1988.

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Keen, Erica C., Alik S. Widge, and Darin D. Dougherty. Functional Neurosurgery in Severe and Treatment-Refractory OCD. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0045.

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Although most patients with obsessive-compulsive disorder (OCD) attain adequate symptomatic relief with conventional first-line treatments, a meaningful fraction remain incapacitated despite numerous medication trials and intensive behavioral therapy (Garnaat et al., 2014). A subset of these patients may be candidates for surgical treatment. Stereotactic neurosurgical lesions have been used successfully since the 1960s to treat patients with especially severe, chronic, treatment-refractory OCD. This chapter briefly reviews the history of psychiatric neurosurgery and the development of the four
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Ray, Sumantra (Shumone), Sue Fitzpatrick, Rajna Golubic, Susan Fisher, and Sarah Gibbings, eds. Monitoring. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199608478.003.0013.

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This chapter discusses the role and responsibilities of monitors/CRAs seeking to improve awareness of their role in a global industry becoming more and more technologically focused. How the role is changing through the introduction of risk based monitoring. Often the only liaison between the Sponsor and each study site, CRAs are crucial to the successful completion of a clinical trial and need to be armed with appropriate knowledge and training to conduct their visits. Successful monitoring requires experience, people skills, management ability and knowledge – of the protocol, CRFs, study drug
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Scolding, Neil. Vasculitis and collagen vascular diseases. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569381.003.0862.

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That part of the clinical interface between neurology and general medicine occupied by inflammatory and immunological diseases is neither small nor medically trivial. Neurologists readily accept the challenges of ‘primary’ immune diseases of the nervous system: these tend to be focussed on one particular target such as oligodendrocytes or the neuro-muscular junction present in predictable ways, and are amenable as a rule to rational, methodological diagnosis, and occasionally even treatment. This is proper neurology.‘Secondary’ neurological involvement in diseases mainly considered systemic in
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Book chapters on the topic "Therapeutic potential etc"

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Barhoi, Dharmeswar, Sarbani Giri, Puja Upadhaya, and Sweety Nath Barbhuiya. "Chemopreventive and Therapeutic Potential of Phytopharmaceuticals Against Oral Cancer." In Handbook of Research on Advancements in Cancer Therapeutics. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-6530-8.ch020.

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Oral cancer is a major public health problem in both developing and developed countries. It is believed to be the eighth most common cancer considering a major risk factor of worldwide morbidity and mortality. Major risk factors of this deadly disease are lifestyle (consumption of smoking and smokeless tobacco, alcohol, betel quid, etc.), unhealthy food, and poor dental care and viral infections. These factors are responsible for mutations in the DNA leading to the initiation of carcinogenesis. Oral carcinogenesis is a multistep process having three distinct phases: initiation, promotion, and progression. Modern cancer treatments (chemotherapy, surgery, radiation therapy, and immunotherapy) are associated with lots of side effects. Thus, phytopharmaceuticals are being used as alternative medicines in the prevention of oral carcinogenesis. Phytopharmaceuticals (such as resveratrol, sulforaphane, quercetin, etc.) have immense potential to prevent cancer development in every phase of carcinogenesis and more importantly, these compounds have fewer side effects.
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G. Nair, Parvathy, Amit Kumar Dixit, and Deepti Dixit. "Immunomodulatory Potential of Bioactives from Selected Ayurvedic Plants." In Therapeutic Implications of Natural Bioactive Compounds. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815080025122030015.

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The history of usage of herbal medicine is as old as human civilization. Plant-based drugs have been an invaluable and incredible source for several medical treatments in the traditional system of medicine. With technological advances, it has become possible to get a clear understanding of active compounds behind the therapeutic effectiveness of these drugs. Plant-derived immunomodulators are one such class of compounds, considered safe alternatives than synthetic immunomodulators which cause serious side effects. These agents can increase the body’s immune responsiveness against pathogens by activating both the innate and adaptive immune systems. Phyto drugs have gained more interest due to their multi-pharmacological potential of being antioxidant, adaptogen, etc. along with immunomodulator. The current book chapter focuses on a few extensively scrutinized immunomodulatory phytocompounds from medicinal plants such as Tinospora cordifolia, Andrographis paniculata, Curcuma longa, Zingiber officinale, Allium sativum, Terminalia chebula, and Piper longum. Phytomedicines from these plants have displayed significant immunomodulatory potential in a variety of experimental (in vitro and in vivo) models, few compounds have exhibited good therapeutic potential in clinical trials also.
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Kachhwaha, Neetu, Mukesh Kumar Sharma, Renu Khandelwal, and Pallavi Kaushik. "Marine Algal Bioactive Metabolites and their Pharmacological Applications." In Therapeutic Implications of Natural Bioactive Compounds. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815080025122030009.

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Thousands of bioactive components are derived from various marine macro and microalgae. Such beneficial algae are considered as a renewable and sustainable resource of bioactives with potential use as dietary food supplement, anti-viral, antiinflammatory, anti-cancerous, anti-oxidant, anti-diabetic, anti-bacterial agents which can provide nutritive and health care benefits. The biochemical infrastructure of algae comprises proteins, lipids, polysaccharides, minerals, vitamins etc. which can be used as nutritional and dietary sources along with use in therapeutics and cosmetics. The therapeutic and industrial applications of the algal derivatives are primarily due to the secondary metabolites such as astaxanthin, aquamin, alginates, fucoidan, omega-3- fatty acids, polyphenols, fucoxanthin, etc. This chapter focuses on various algae derived bioactives and their wide range of applications.
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Nazir, Ishrat, and Sajad Ahmad Gangoo. "Pharmaceutical and Therapeutic Potentials of Essential Oils." In Essential Oils - Advances in Extractions and Biological Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102037.

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It is a common perspective that medicinal plants have played and continue to perform an undeniably major role in the lives of people worldwide. Essential oils are the key constituents of medicinal herbs and their biological activities have been discovered since ancient times and are enormously utilised in multiple industries. The essential oils possess important biological properties like antibacterial, antioxidant, antiviral, insecticidal, etc. Because of these unique features they are more acceptable and are utilised in various fields throughout the world. In the cosmetics industry they play an important role in the development of perfumes while in the food industry they have been used as food preservatives. Essential oil components are interestingly utilised for pharmaceutical applications. The most investigated properties are antioxidant, anti-inflammatory, antimicrobial, wound-healing, anxiolytic activities etc. The current thrust area is evaluation for aromatherapy and anti-cancer, as it is noted that essential oils reported in plants may prevent, inhibit, or even reverse formation of cancerous cells. The aim of this chapter is to provide a concise and comprehensive overview on the therapeutic and pharmaceutical potential of essential oils in the current scenario.
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Sharma, Srijana, Yachana Mishra, Shubham Bisht, Neha Sharma, and Vijay Mishra. "An Overview of Biomaterial Toxicity and Excretion." In Bionanotechnology: Next-Generation Therapeutic Tools. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815051278122010003.

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Biomaterial is a growing family of materials with specific physicochemical properties. Significant studies have been made to characterize the potential in vivo and in vitro toxicity of biomaterials. The cytotoxicity may be attributed to variations in the physicochemical properties, target cell types, particle dispersion methods, etc. The reported cytotoxicity effects mainly include the impact on the biological system and organ-specific toxicity such as CNS toxicity, lung toxicity, cardiac toxicity, dermal toxicity, gastrointestinal toxicity, etc. Despite cellular toxicity, the immunological effects of biomaterials, such as the activation of pulmonary macrophages and associated inflammation, have been extensively studied. In this chapter, the latest research results on the toxicological profiles of nanomaterials, highlighting both the cellular toxicities and the immunological effects, have been incorporated. This analysis also offers details on the overall status, patterns, and research needs for dealing with the toxicological behavior of biomaterials.
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Patil, B., A. Tiwari, S. P. Pandey, T. Shukla, and N. Upmanyu. "Potential Approaches for Delivery of Surface Decorated Nano-carriers in the Management of Carcinoma." In Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080506123010006.

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Cancer is one of the leading causes of death worldwide, affecting the entire world irrespective of demographic and economic variations. In the last few decades, development concerning cancer diagnosis and treatment has witnessed significant advancement but still lags far behind in terms of targeted delivery to the targeted site without much adverse effect. Changes in the structure and pathophysiology of cancer tissue, like leaky vasculature, pH, temperature, over-expression of certain receptors, etc., are being utilized for the development of different approaches of targeted drug delivery to such tissues avoiding the adverse effects associated with cancer chemotherapy. The utilization of enhanced permeability retention (EPR) and surface modification of the nano-sized formulation with different ligands, such as proteins, aptamers, antibodies, etc., are some common ways used for the above. The current chapter includes the different nano-carriers used for targeted drug delivery of medicaments to the affected site along with their surface modification which has shown their significance in the management of cancer.
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Rathinam, W. V. Celcia Gnana, S. Bragadeeswaran, S. Kumaresan, et al. "Exploring the Antimicrobial Potential of Marine Bio Resources." In Advances in Medical Technologies and Clinical Practice. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-5878-8.ch013.

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The diverse marine environment compared to terrestrial is a great treasure in discovering many new bioactive substances. By living in a competitive and hostile environment, marine organisms tend to survive and live within complex communities and also have close associations with others. Due to the ecological pressure such as predation, habitat competition, variation in tide, etc. as a response, the marine organisms produce composite secondary metabolites which are unique and abundant in marine sources that can be used as anti-microbial agents such as antiviral, antibacterial, antifungal and antiprotozoal agents. Since marine organisms produce a variety of compounds with antimicrobial activities they can be used in the production of pharmacological products to treat infections, diseases, etc. This chapter discusses the potential sources that are available in marine organisms that can act as therapeutic agents with antimicrobial activities. It also briefly explains different bioactive substances produced by different marine organisms that can be used in pharmaceutical industries.
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Joshi, Veenu, Akanksha Sahu, Ajay James, Amber Vyas, and Neelu Joshi. "Plant Cardenolides: Multifunctional Medicinal Agents." In Steroids and their Medicinal Potential. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/789815049336123010009.

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Cardenolides are a class of compounds steroidal in nature, belonging to the cardiac glycoside group of secondary metabolites. They consist of a sugar part and a non-sugar part consisting of a steroidal cyclopentanoperhydrophenanthrene ring with lactone substitution at the β-17 position. Cardenolides are found in angiosperm plant families like Plantiginaceae, Asclepiadaceae, Apocynaceae, Brassicaceae, Cruciferae, Liliaceae, Moraceae, Ranunculaceae, and Scrophulariaceae. These include some important glycosides, such as digitoxin, digoxin, Ouabain, Calotropin, etc. with profound pharmacological potential. Moreover, cardenolides have toxic effects for which these have been used in poison arrows and for self-harm purposes. Traditionally, these were used to treat congestive heart failure. However, recently they have emerged as promising agents to exhibit anticancer, antiviral, anti-inflammatory, neuroprotective, and various other therapeutic roles. Cardenolides like Digoxin and Digitoxin have been used in the treatment of heart failure and atrial fibrillation. Toxicarioside A, and Calotropin have been reported to suppress tumor growth and are used as anticancer agents, Strophalloside and Oubain are reported to be involved in apoptosis. Oleandrin is an antiproliferative agent and can inhibit IL-8 which is responsible for cystic fibrosis.
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Jayaram, Saravanan, Praveen Thaggikuppe Krishnamurthy, Meghana Joshi, and Vishnu Kumar. "Nrf2 as a Potential Therapeutic Target for Treatment of Huntington’s Disease." In From Pathophysiology to Treatment of Huntington's Disease [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.103177.

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Oxidative stress-induced neuronal damage plays a significant role in pathogenesis of several neuro-degenerative disorders including Huntington’s disease. In Huntington’s disease, oxidative stress-induced neuronal damage is reported to be mediated by PGC-1α and microglial cells. This development led to various clinical trials that tested the efficacy of several exogenous antioxidants such as vitamin E, vitamin C, etc. to prevent the oxidative stress-induced cell damage in several neuro-degenerative disorders. But these randomized clinical trials did not find any significant beneficial effects of exogenous antioxidants in neuro-degenerative disorders. This forced scientists to search endogenous targets that would enhance the production of antioxidants. Nrf2 is one such ideal target that increases the transcription of genes involved in production of antioxidants. Nrf2 is a transcription factor that controls the expression of antioxidant genes that defend cells against oxidative stress. This chapter focuses on the role of oxidative stress in Huntington’s disease and explores the therapeutic benefits of Nrf2 activators.
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Kumar, Nitesh, Ruchika Devi, Pratibha, Harinder Singh Banyal, Shivali Sharma, and Monika Kaundal. "A Comprehensive Review on the Potential of Some Medicinal Plants for the Treatment of Eating Disorders." In Neuroscientific Insights and Therapeutic Approaches to Eating Disorders. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-3230-6.ch014.

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Eating disorders are illnesses of the mind and body. Anorexia nervosa, bulimia nervosa, binge eating disorder, etc. are examples of eating disorders that affect people of every ethnic background and age, and pose a serious threat to worldwide public health. Several medicinal plants have demonstrated promising therapeutic properties for addressing various aspects of eating disorders. For example, Nigella sativa exhibits anxiolytic and appetite-regulating effects, suggesting its potential utility in treating anorexia nervosa. Additionally, the appetite-suppressing qualities of herbal therapies like Centella asiatica have been studied, making them viable supplementary therapy for people who struggle with excessive consumption of food. Overall, integrating medicinal plants into comprehensive treatment approaches for eating disorders holds promise for improving clinical outcomes and enhancing the holistic well-being of affected individuals.
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Conference papers on the topic "Therapeutic potential etc"

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Bradic, Jovana V., Anica M. Petrovic, and Vladimir Lj Jakovljevic. "Can a three-week administration of methanol extract of wild garlic modulate systemic redox state in hypertensive rats?" In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.575b.

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Wild garlic (Allium ursinum) is a widespread perennial herbaceous plant that has wide therapeutic applications and it is used as well as food. Natural preparations based on wild garlic have been used for gastrointestinal tract disorders, as antioxidants, antihypertensive, hypolipidemic agents, etc. Nevertheless, the data related to the effects of chronic wild garlic extract consumption on systemic redox state in hypertensive animals is yet to be understood. Therefore, the main goal of this study was to examine the effects of a three-week application of ethanolic extract from wild garlic on oxi
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Kang, Jia-Chen, Min Wang, and Xiao-Yan Yuan. "Bicomponent Fibrous Scaffolds of Controlled Composition for Tissue Engineering Applications." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-10989.

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Electrospinning has been widely studied for constructing tissue engineering scaffolds because of the morphological and size effects of electrospun fibers on cell behavior. Research on electrospun tissue engineering scaffolds has been based mainly on using solutions of single polymer or blends of polymers dissolved in common solvents, which has put limitations to scaffolds that can be built. There is an increasing need for using the multi-source and multi-power electrospinning approach to fabricate multicomponent fibrous scaffolds because these scaffolds have great potential for tissue engineer
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Kovačević, Sanjin, Nikola Mitovic, Predrag Brkić, and Jelena Nesovic Ostojic. "Hyperbaric oxygenation and Acute kidney injury – Data obtained from experimental studies." In 7th International Congress of Cardionephrology KARNEF 2025. Punta Niš, 2025. https://doi.org/10.46793/karnef25.253k.

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Despite constant achievements in treatment, acute kidney injury (AKI) remains a significant public health problem and a cause of mortality in the human population. In developed countries, AKI is a significant and frequent hospital complication, especially among patients admitted to intensive care units, where mortality rates can reach up to 50%. In addition, AKI has been implicated as an independent risk factor for the development of chronic kidney disease. Hyperbaric oxygenation (HBO) has been used as a primary or adjunctive therapy for the past 50 years, both in experimental and clinical stu
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Kang, Jia-Chen, Min Wang, and Xiao-Yan Yuan. "Biodegradable Micro- and Nanofibers Fabricated Through Electrospinning for Tissue Engineering and Controlled Release Applications." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-11000.

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Electrospinning is a simple and versatile technique for producing micro- and nanofibers. It has been shown that electrospun tissue engineering scaffolds mimic the structure of the extracellular matrix of human body tissues. These scaffolds can improve cell attachment behavior and subsequent cell proliferation and differentiation. On the other hand, due to their large surface area to volume ratio and porous morphology, electrospun micro- and nanofibers are potentially useful for the controlled release of therapeutic agents (drugs and therapeutic biomolecules) in human bodies. In this study, ele
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Alsawaf, Shahed, Tuğba Bal, and Zihni Onur Çalışkaner. "EXPLORING THE POTENTIAL OF DRUG REPURPOSING AGAINST ABNORMALLY REGULATED CELL-MATRIX INTERACTIONS IN THE TREATMENT OF PANCREATIC CANCER (A COMPUTATIONAL STUDY)." In STRA International Conference on Engineering & Technology, 09-10 October 2024, Istanbul. Global Research & Development Services, 2024. https://doi.org/10.20319/icstr.2024.9192.

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Pancreatic ductal adenocarcinoma (PDAC) represents one of the most aggressive cancers, with a 5-year survival rate of only 8%. The progression of the disease is significantly influenced by the tumor microenvironment, especially by cell-extracellular matrix (ECM) interactions. The aim of this study is to repurpose small molecules as inhibitor candidates to jointly target key receptors for the ECM attachment, specifically discoidin domain receptors (DDR1 and DDR2), which are implicated in promoting tumor growth through cell-collagen interactions.Using a computational drug repurposing framework,
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Kruszewski, Artur, Marek Kruszewski, Elena Cherkashina, Ilia Cherkashin, and Liu Siliang. "Interpretation of Chinese hand-to-hand fighting systems and therapeutic exercises from the perspective of the INNOAGON methodology." In 15th International Conference on Applied Human Factors and Ergonomics (AHFE 2024). AHFE International, 2024. http://dx.doi.org/10.54941/ahfe1005292.

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The traditional Chinese aerobic fitness exercise tai chi, is a form of low to moderate intensity physical activity. Tai chi is a good example of both therapeutic exercise and a form of preparation for gentle hand-to-hand combat (especially as safe self-defence, also from the perspective of a potential aggressor) . In Chinese society, these forms of exercise are the primary means of preventive health, active lifestyle and, in a sense, conventional physiotherapy or even rehabilitation. Many schools of tai chi based on the same theoretical principles of exercise are still emerging in China. There
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Madić, Višnja, Aleksandra Petrović, and Perica Vasiljević. "ETHNOPHARMACOLOGY OF DIABETES: FROM TRADITIONAL RECIPES TO MODERN MEDICINE." In 58. Kongres Antropološkog društva Srbije. Antropološko društvo Srbije, 2025. https://doi.org/10.46793/ads25.34m.

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Diabetes is one of the most prevalent chronic diseases of the 21st century. Current pharmacological interventions used in the management of this condition regulate hyperglycemia; however, they do not fully prevent the onset or progression of its secondary complications, including diabetic nephropathy, hepatic dysfunction, osteoporosis, neuropathy, retinopathy, cardiovascular diseases, increased risk of dementia, etc. Consequently, a growing number of individuals with diabetes, in addition to conventional pharmacotherapy, are incorporating herbal alternatives derived from traditional medicine,
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Gadetsky, O. G. "ЦЕННОСТНО–ОРИЕНТИРОВАННАЯ ПСИХОЛОГИЯ, КАК ОДНО ИЗ НАПРАВЛЕНИЙ РЕАЛИЗАЦИИ ПОТЕНЦИАЛА ОБЪЕДИНЕНИЯ ОБЩЕСТВА". У ПЕРВЫЙ МЕЖКОНТИНЕНТАЛЬНЫЙ ЭКСТЕРРИТОРИАЛЬНЫЙ КОНГРЕСС «ПЛАНЕТА ПСИХОТЕРАПИИ 2022: ДЕТИ. СЕМЬЯ. ОБЩЕСТВО. БУДУЩЕЕ». Crossref, 2022. http://dx.doi.org/10.54775/ppl.2022.64.59.001.

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Value-oriented psychology reveals the potential of the individual. At the same time, the basis of the personality is the spiritual and moral core, spiritual and moral values. These values are not selfish, they form our relationships with other people, in which such qualities as respect, gratitude, sensitivity, attentiveness, compassion, mercy, etc. are manifested. Also a person becomes more socially oriented, able to act for the benefit of others. Such a person begins to create an atmosphere of harmony and cooperation in society, instead of an atmosphere of destruction, selfishness, manipulati
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Liang, Ziting, Haoqian Yang, Chuang Lu, et al. "A Novel MR Safe Needle Insertion Robot for Abdominal Interventions." In The Hamlyn Symposium on Medical Robotics. The Hamlyn Centre Imperial College London, 2024. http://dx.doi.org/10.31256/hsmr2024.63.

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Liver and kidney tumours are among the most common and fatal abdominal cancers, posing a substantial threat to both life and quality of living. Image-guided minimally invasive percutaneous interventions, including biopsy and ablation, have become effective and popular diagnostic and therapeutic approaches due to significant advantages such as greatly reducing perioperative complications and recovery time [1]. In conventional interventions, surgeons navigate needle probes to lesions guided by medical imaging techniques such as Computed Tomography (CT) and Ultrasound (US) Imaging. However, Magne
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Sarkar, Daipayan, A. Haji-Sheikh, and Ankur Jain. "Theoretical Analysis of Transient Bioheat Transfer in Multi-Layer Tissue." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53392.

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Heat conduction in skin tissue is a problem of significant technological importance. A theoretical understanding of such a problem is essential as it may lead to design potential therapeutic measures for needed cancer therapy or novel medical devices for various applications including hyperthermia. To understand the physical phenomenon of energy transport in biological systems a transient model is chosen for this study. The most common transport equation to estimate temperature distribution in humans was developed by H.H. Pennes and is popularly known as the Pennes bioheat transfer equation. A
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Reports on the topic "Therapeutic potential etc"

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Friedmann, Michael, Charles J. Arntzen, and Hugh S. Mason. Expression of ETEC Enterotoxin in Tomato Fruit and Development of a Prototype Transgenic Tomato for Dissemination as an Oral Vaccine in Developing Countries. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7585203.bard.

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The broad objective of the project was to develop a feasible approach to combat diarrheal disease caused by ETEC through the development of a low-cost oral immunogen in tomato fruit, expressed in the context of a prototype tomato that would answer the shortcomings of plant oral vaccines, especially in terms of produce handling and control of gene escape. Specifically, the goals for Boyce Thompson Institute (BTI) on this project were to develop transgenic tomato lines that express the enterotoxigenic E. coli (ETEC) heat-labile enterotoxin (LT) subunits A and/or B for use in oral edible vaccines
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Practitioner Review: Neurobiological consequences of childhood maltreatment – clinical and therapeutic implications for practitioners. ACAMH, 2023. http://dx.doi.org/10.13056/acamh.25785.

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Paper from the JCPP - 'In this report, we explore key validated alterations in brain structure, function, and connectivity associated with exposure to childhood maltreatment as potential mechanisms behind their patients' clinical presentations.' Jacqueline A. Samson (pic) et al.
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