Academic literature on the topic 'Therapeutic Responses against Stress and Chronic Infections'

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Journal articles on the topic "Therapeutic Responses against Stress and Chronic Infections"

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Ferraz, Maria Pia. "The Potential of Cannabidiol in the Management of Oral Infections." Applied Sciences 15, no. 10 (2025): 5736. https://doi.org/10.3390/app15105736.

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Oral infections, caused by bacterial, fungal, and viral pathogens, are a significant source of dental morbidity and can lead to systemic complications, especially in immunocompromised individuals. Complex microbial interactions and host immune responses drive common conditions such as dental caries, periodontal disease, oral candidiasis, and herpetic lesions. Conventional antimicrobial therapies face limitations due to resistance and adverse effects, prompting interest in alternative treatments. Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis sativa, has emerged as a promi
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Griffin, John Lawrence, Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, and Gopal Nayak. "Effect of the Energy of Consciousness (The Trivedi Effect®) on Physicochemical, Thermal, Structural, and Behavioral Properties of Magnesium Gluconate." Chemical and Biomolecular Engineering 2, no. 2 (2017): 113–23. https://doi.org/10.5281/zenodo.884138.

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Magnesium gluconate is an organometallic pharmaceutical compound used for the prevention and treatment of hypomagnesemia. The objective of the current research work was to examine the influence of The Trivedi Effect®-Energy of Consciousness Healing Treatment (Biofield Energy Treatment) on magnesium gluconate for the alteration in the physicochemical, structural, thermal and behavioral properties using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Magnesium gluconate was divided into two parts – one part was control without any Biofield Energy Treatment, while another part was t
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Stamova, Sylvia, Neli Ermenlieva, Gabriela Tsankova, Silviya P. Nikolova, and Emilia Georgieva. "Synergistic Antimicrobial Activity of Essential Oils and Vitamin C: Mechanisms, Molecular Targets and Therapeutic Potential." Applied Sciences 15, no. 8 (2025): 4294. https://doi.org/10.3390/app15084294.

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Antimicrobial resistance (AMR) poses an increasing challenge to modern medicine, necessitating the search for novel therapeutic strategies. This study evaluates the synergistic antimicrobial activity of oregano essential oil (OEO) and thyme essential oil (TEO) in combination with vitamin C against clinically relevant pathogens. The antimicrobial activity was assessed using MIC, MBC and MFC assays, alongside in silico analyses utilizing Swiss Target Prediction, STRING and Reactome to identify potential molecular targets and underlying biological mechanisms. The results demonstrate that the comb
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Schnitzer, Debra Jane, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "Investigation of Physicochemical, Spectral, and Thermal Properties of Sodium Selenate Treated with the Energy of Consciousness (The Trivedi Effect®)." American Journal of Life Sciences 5, no. 1 (2017): 27–37. https://doi.org/10.5281/zenodo.835625.

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Sodium selenate is used for the prevention and treatment of various disorders like cancer, diabetes, inflammation diseases, etc. The objective of the current study was to evaluate the effect of The Trivedi Effect®-Energy of Consciousness Healing Treatment (Biofield Energy Treatment) on physicochemical, spectral, and thermal properties of The Trivedi Effect®-Biofield Energy Treated sodium selenate using various analytical methods such as PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Sodium selenate was divided into two parts – one part was control without any treatment and anoth
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Hewson, Chris K., Alexander Capraro, Sharon L. Wong та ін. "Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells". Antioxidants 9, № 12 (2020): 1204. http://dx.doi.org/10.3390/antiox9121204.

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Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvements to current antioxidant therapeutic strategies are needed. The dietary supplement, γ-glutamylcysteine (GGC), which is the immediate precursor to glutathione, rapidly boosts cellular glutathione levels following a single dose in healthy individuals. Efficacy of GGC against oxidative stress induced by Pseudomonas aeruginosa, which is a common and c
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Amen, Radwa Abdallnasser. "Therapeutic potential and characteristics of Smp43 peptide (scorpion venom) and its interaction with cellular signaling pathways: A review." Innovative Medicines & Omics 1, no. 1 (2024): 4353. http://dx.doi.org/10.36922/imo.4353.

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Smp43 peptide, derived from the venom of the scorpion Scorpio Maurus Palmatus, exhibits significant potential across a range of therapeutic domains due to its diverse biological actions. Interestingly, Smp43 possesses robust anti-inflammatory and antioxidant properties, enabling it to scavenge free radicals and suppress pro-inflammatory cytokines. This dual functionality makes Smp43 a viable candidate for the treatment of conditions associated with oxidative stress and chronic inflammation. Furthermore, its broad-spectrum antibacterial activity is indicative of its efficacy against both Gram-p
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Khan, Muhammad Zahoor, Wenting Chen, Xiaotong Liu та ін. "An Overview of Bioactive Compounds’ Role in Modulating the Nrf2/Keap1/NF-κB Pathway to Alleviate Lipopolysaccharide-Induced Endometritis". International Journal of Molecular Sciences 25, № 19 (2024): 10319. http://dx.doi.org/10.3390/ijms251910319.

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Endometritis is a common inflammatory condition of the uterine endometrial lining that primarily affects perinatal dairy animals and causes significant economic losses in agriculture. It is usually triggered by pathogenic bacteria and is associated with chronic postpartum reproductive tract infections. Bacterial lipopolysaccharides (LPSs) are known to increase levels of reactive oxygen species (ROS), leading to oxidative stress and inflammation through the activation of the NF-κB signaling pathway and the inhibition of Nrf2 nuclear translocation, which regulates antioxidant response elements (
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Hornung, Matthew Charles, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "LC-MS, GC-MS, and NMR Spectroscopic Analysis of Withania somnifera (Ashwagandha) Root Extract After Treatment with the Energy of Consciousness (The Trivedi Effect®)." European Journal of Biophysics 5, no. 2 (2017): 27–37. https://doi.org/10.5281/zenodo.844961.

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Withania somnifera (Ashwagandha) root extract is very popular ancient herbal medicine. The current study was designed to investigate the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment on the structural characterization of the ashwagandha root extract using LC-MS, GC-MS, and NMR spectroscopy. Ashwagandha root extract was divided into two parts – one part was control, without any Biofield Energy Healing Treatment, while another part was treated with the Biofield Energy Healing Treatment remotely by eighteen renowned Biofield Energy Healers and defined as the Biofield E
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Frippiat, Thibault, Tatiana Art, and Catherine Delguste. "Silver Nanoparticles as Antimicrobial Agents in Veterinary Medicine: Current Applications and Future Perspectives." Nanomaterials 15, no. 3 (2025): 202. https://doi.org/10.3390/nano15030202.

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Silver nanoparticles (AgNPs) have gained significant attention in veterinary medicine due to their antimicrobial properties and potential therapeutic applications. Silver has long been recognized for its ability to combat a wide range of pathogens, and when engineered at the nanoscale, silver’s surface area and reactivity are greatly enhanced, making it highly effective against bacteria, viruses, and fungi. This narrative review aimed to summarize the evidence on the antimicrobial properties of AgNPs and their current and potential clinical applications in veterinary medicine. The antimicrobia
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Chippalkatti, Rohan, Kirti Badave, Ayesha Alim Khan, and Sandhya Rane. "Anti-quorum Sensing, Oxidative Stress and Anti-Biofilm Inducing Abilities of Vitamin K3 Analogues Against Chronic Respiratory Infection of Mucoid Variants Pseudomonas aeruginosa Strain PAO1." International Journal of Current Microbiology and Applied Sciences 13, no. 7 (2024): 74–85. http://dx.doi.org/10.20546/ijcmas.2024.1307.009.

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Almost all antibiotics target either bacterial function or biofilms but do not consider the damage due to host responses, thus, even if the bacteria are eliminated, the tissue damage cannot be prevented. The mucoid phenotype and oxidative stress severely limit the efficacy of current therapeutics for chronic respiratory infections (CRI) of Pseudomonas aeruginosa in cystic fibrosis (CF) patients. In the present study, we examined the activity of a novel set of VitaminK3 derivatives on biofilms of the mucoid variants of P.aeruginosa. Acyl-homoserine lactones (AHLs) an important signaling molecul
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Book chapters on the topic "Therapeutic Responses against Stress and Chronic Infections"

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Pushpalatha, Deepta Shirin S. P. Sundararajan, Srinivasan Kumaraswamy, Ganesh Kumar Selvaraj, et al. "Plant-Derived Bioactive Compounds." In Advances in Medical Diagnosis, Treatment, and Care. IGI Global, 2023. http://dx.doi.org/10.4018/979-8-3693-0703-8.ch011.

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Inflammation is a robust immune response against exogenous stimulation processes like microbial invasion and physical injury. Despite inflammation being an essential host-defence mechanism, their chronic stage is highly associated with severe inflammatory disorders such as cancer and heart diseases. Natural bioactive compounds have been contributing a solid base for improving contemporary therapeutic agents against various inflammatory diseases. Due to their natural source and pharmacological benefits, medicinal plants have been utilized as a significant source of anti-inflammatory drugs. The
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Goswami, Aranyak. "Future Discovery Path to Combat Salmonella Biofilm Infection." In Salmonella Biofilms. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781837677047-00218.

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Salmonella, a significant foodborne pathogen, forms biofilms that enhance its resilience against environmental stressors and antimicrobial treatments, complicating infection control in food processing and the gastrointestinal tract of hosts. This chapter elucidates the biofilm formation process, highlighting its role in chronic infections and antimicrobial resistance. Comprehensive control measures include enzymatic degradation of biofilm matrix components using proteases, polysaccharide-degrading enzymes, DNases, and lipases. Biofilm-specific phage therapy targets and disrupts Salmonella with
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Iqbal, Sajid, Mehwish Malik, Bushra Mustafa, and Hussnain Ahmed Janjua. "Clinical and Therapeutic Potential of Bacillus subtilis Antimicrobial Peptides." In Bacillus subtilis - Functionalities and Emerging Applications [Working Title]. IntechOpen, 2024. https://doi.org/10.5772/intechopen.1007960.

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The bioactive peptides produced by Bacillus subtilis have garnered significant attention for their diverse bioactivities and promising therapeutic applications. These peptides exhibit broad-spectrum activity against bacterial, viral, fungal, and parasitic infections, making them potent candidates for treating drug-resistant pathogens. Further, these peptides exhibited anticancer activity by selectively targeting cancer cells, inducing apoptosis, and inhibiting tumor cell migration and invasion. Beyond their direct antimicrobial and anticancer properties, B. subtilis peptides also possess immun
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Hamza Abbas, Syed, Hafiza Sehrish Kiani, Faryal Gohar, et al. "Understanding the Role of Bacterial Biofilm in Antibiotic Resistance: Defensive Strategies and Clinical Challenges." In Exploring Bacterial Biofilms [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1009440.

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Bacterial biofilms significantly cause persistent exacerbation of infections in the clinical setting. These groups of microorganisms are highly resistant to host immune responses and conventional antibiotic therapies, whereas they are embedded in an extracellular matrix. This chapter provides more detailed information on the mechanism of biofilm formation involving key stages of adherence, maturation, and spread, including the composition and structure of a biofilm matrix. This chapter further explores how biofilms contribute to antibiotic resistance, including physical barriers to drug penetr
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R. Jothi Lakshmi, Mrs, R. Selvakumar, K. Pushparaj, et al. "HERBAL MEDICINES ON RESPIRATORY INFLAMMATION-RELATED DISEASES." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 18. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn18p10ch2.

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Respiratory inflammation-related diseases pose significant health challenges globally, necessitating effective therapeutic interventions. Herbal medicines have emerged as promising candidates for managing these conditions due to their diverse bioactive compounds with anti-inflammatory properties. This abstract reviews the role of herbal medicines in alleviating respiratory inflammation and associated disorders. Herbal medicines offer a rich source of phytochemicals such as flavonoids, terpenoids, and polyphenols, known for their anti-inflammatory, antioxidant, and immunomodulatory effects. The
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