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Relevant bibliographies by topics / Thermal hypoalgesia method

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Journal articles

Academic literature on the topic 'Thermal hypoalgesia method'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Thermal hypoalgesia method"

1

Kousar, Begum* Naziya Begum Shaik Reshma Wajiha Fatima Mariyanaaz Ali and Ayesha Sultana. "PTEROCARPUS MARSUPIUM EXTRACTION AND EVALUATION FOR DIABETIC NEUROPATHY." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 1888–97. https://doi.org/10.5281/zenodo.826969.

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Herbal medicines are considered to offer gentle means of managing chronic diseases at a lower cost. Traditional Medicines derived from medicinal plants are used by about 60% of the world’s population. Diabetes is an important human ailment afflicting many from various walks of life in different countries. In India it is proving to be a major health problem, especially in the urban areas. Pterocarpus marsupium. (PM) heartwood and bark have been majorly used as antidiabetic remedies in many cultures for thousands of years. The aim of this research is to address the existing evidence on antidiabe

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2

Safakhah, Hossein Ali, Abbas Ali Vafaei, Azin Tavasoli, Simin Jafari, and Ali Ghanbari. "Role of Muscarinic Receptors in Hypoalgesia Induced by Crocin in Neuropathic Pain Rats." Scientific World Journal 2020 (November 25, 2020): 1–7. http://dx.doi.org/10.1155/2020/4046256.

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Objective. Crocin as an important constituent of saffron has antineuropathic pain properties; however, the exact mechanism of this effect is not known. The aim of this study was whether the hypoalgesic effect of crocin can be exerted through muscarinic receptors. Materials and Methods. In the present project, 36 male Wistar rats (200 ± 20 g) were used. Animals randomly divided into six groups (sham, neuropathy, neuropathy + crocin, neuropathy + atropine 0.5 mg/kg, neuropathy + atropine 1 mg/kg, and neuropathy + atropine 1 mg/kg + crocin). Neuropathy was induced by the chronic constriction inju

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3

Jones, Matthew D., James L. Nuzzo, Janet L. Taylor, and Benjamin K. Barry. "Aerobic Exercise Reduces Pressure More Than Heat Pain Sensitivity in Healthy Adults." Pain Medicine 20, no. 8 (2019): 1534–46. http://dx.doi.org/10.1093/pm/pny289.

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Abstract Objectives The hypoalgesic effects of exercise are well described, but there are conflicting findings for different modalities of pain; in particular for mechanical vs thermal noxious stimuli, which are the most commonly used in studies of exercise-induced hypoalgesia. The aims of this study were 1) to investigate the effect of aerobic exercise on pressure and heat pain thresholds that were well equated with regard to their temporal and spatial profile and 2) to identify whether changes in the excitability of nociceptive pathways—measured using laser-evoked potentials—accompany exerci

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4

Paley, Carole A., and Mark I. Johnson. "Investigation into the Effects of Using Two Or Four Acupuncture Needles with Bidirectional Rotation on Experimentally-Induced Contact Heat Pain in Healthy Subjects." Acupuncture in Medicine 33, no. 1 (2015): 23–29. http://dx.doi.org/10.1136/acupmed-2014-010617.

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Objectives There is growing evidence from experimental studies that the acupuncture dose or technique influences the speed of onset of hypoalgesia. The aim of this study was to investigate the effects of acupuncture using two or four needles on experimental contact thermal pain in healthy volunteers. Methods Forty two participants were randomised into three groups: four-needle group (LI4, LI11, LI10, TE5), two-needle group (verum at LI4, LI11 and mock at LI10, TE5) and mock acupuncture group (LI4, LI11, LI10, TE5). Each participant rated pain intensity (visual analogue scale, VAS) to a series

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5

Calcutt, Nigel A., Jason D. Freshwater, and John S. O’Brien. "Protection of Sensory Function and Antihyperalgesic Properties of a Prosaposin-derived Peptide in Diabetic Rats." Anesthesiology 93, no. 5 (2000): 1271–78. http://dx.doi.org/10.1097/00000542-200011000-00021.

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Background Short-term diabetes causes sensory disorders in rats ranging from thermal hypoalgesia to exaggerated behavioral responses to other sensory stimuli. As impaired neurotrophic support may promote sensory nerve disorders during diabetes, the authors investigated whether TX14(A), a neurotrophic peptide derived from prosaposin, was able to ameliorate nerve disorders in diabetic rats. Methods TX14(A) was delivered by intraperitoneal or intrathecal injection to control or streptozotocin-diabetic rats in either single or multiple (three times weekly) dose regimens. Efficacy was measured agai

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Khaleghzadeh-Ahangar, Hossein, Forouzan Sadeghimahalli, Shaghayegh Khandan, Sima Shahabi, and Aliakbar Moghadamnia. "Insulin Within the Arcuate Nucleus Has Paradoxical Effects on Nociception in Healthy and Diabetic Rats." Basic and Clinical Neuroscience Journal 11, no. 6 (2020): 727–36. http://dx.doi.org/10.32598/bcn.11.6.1983.1.

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Introduction: Broad neural circuits originate from the hypothalamic arcuate nucleus and project to many parts of the brain which are related to pain perception. Insulin receptors are found in the arcuate nucleus. Since nociception may be affected in type 1 diabetes, the present study aimed to investigate the intra-arcuate nucleus insulin role in pain perception in streptozotocin (STZ)-induced diabetic and healthy rats. Methods: Regular insulin was microinjected within the arcuate nucleus and the pain tolerance was measured using the hot plate and the tail-flick apparatus in diabetic rats. Resu

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7

Sorkin, Linda S., Tony L. Yaksh, and Carmen M. Doom. "Pain Models Display Differential Sensitivity to Ca2+-Permeable Non-NMDA Glutamate Receptor Antagonists." Anesthesiology 95, no. 4 (2001): 965–73. http://dx.doi.org/10.1097/00000542-200110000-00028.

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Background Ca2+-permeable non-N-methyl-D-aspartate receptors are found in the spinal dorsal horn and represent a presumptive target for glutamatergic transmission in nociceptive processing. This study characterized the analgesic profile associated with the blockade of these spinal receptors by intrathecally delivered agents known to act at these receptors, the spider venom Joro toxin (JST) and philanthotoxin. Methods Philanthotoxin (0.5, 2.5, or 5 microg) or JST (5 microg) was given spinally before thermal injury to the paw. JST (5 microg) was also given 10 min before subcutaneous formalin inj

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8

Safakhah, Hossein Ali, Farzaneh Tamimi, Nasroallah Moradi kor, Ahmad Reza Bandegi, and Ali Ghanbari. "Hypoalgesic effect of Spirulina platensis on the sciatic neuropathic pain induced by chronic constriction injury in male rats." Biomedical Research and Therapy 5, no. 9 (2018): 2671–79. http://dx.doi.org/10.15419/bmrat.v5i9.477.

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Background: It has been revealed that herbal medicines have a palliative effect on pain. In the present study, the hypoalgesic effect of Spirulina platensis (microalgae) on the neuropathic pain induced by chronic constriction injury (CCI) was investigated. Methods: In the present study, 74 adult male Wistar rats weighing 200-220 grams were used. For inducing neuropathic pain, CCI was performed on the left sciatic nerve. Spirulina platensis was intragastrically administered daily for 3 weeks. Mechanical allodynia and thermal hyperalgesia were assessed by Von Frey hairs and plantar test de

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9

Coppey, Lawrence J., Amey Holmes, Eric P. Davidson, and Mark A. Yorek. "Partial Replacement with Menhaden Oil Improves Peripheral Neuropathy in High-Fat-Fed Low-Dose Streptozotocin Type 2 Diabetic Rat." Journal of Nutrition and Metabolism 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/950517.

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Aims. To determine the effect of partial replacement of a high-fat diet with menhaden oil on diabetic neuropathy in an animal model of type 2 diabetes.Materials and Methods. High-fat/low-dose streptozotocin diabetic rats were used to examine the influence of replacing 50% of the source of the high-fat diet (lard) with menhaden oil, a natural source of n-3 fatty acids, on diabetic neuropathy. Endpoints included analyses of glucose tolerance, fatty liver disease, serum and liver fatty acid composition, serum lipid and adiponectin levels, motor and sensory nerve conduction velocity, thermal sensi

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10

Nozaki-Taguchi, Natsuko, and Tony L. Yaksh. "Characterization of the Antihyperalgesic Action of a Novel Peripheral Mu-opioid Receptor Agonist-Loperamide." Anesthesiology 90, no. 1 (1999): 225–34. http://dx.doi.org/10.1097/00000542-199901000-00029.

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Background Preclinical and clinical evidence indicates that locally administered opioid agonists produce an antihyperalgesic effect through peripheral opioid receptors in inflamed tissue. Loperamide, a mu opioid agonist, does not cross the blood-brain barrier and therefore lacks central effects after systemic administration. The authors defined the effects of topical loperamide on a thermal injury-induced hyperalgesia. Methods In halothane-anesthetized rats, thermal injury was induced by placing the plantar surface of a hindpaw on a hot plate (52.0+/-1 degrees C) for 45 s. Loperamide was prepa

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