Dissertations / Theses on the topic 'Thermode de contact'
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Geyn, Sergey. "FEM-BEM procedures for elastoplastic thermo-viscoplastic contact problems." [S.l.] : [s.n.], 2007. http://deposit.ddb.de/cgi-bin/dokserv?idn=984384472.
Full textMishra, Prakash Chandra. "Transient thermo elastohydrodynamics of piston compression ring-cylinder liner contact." Thesis, Loughborough University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547397.
Full textKadiric, Amir. "Thermo-mechanical analysis of layered rough surface contacts." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413501.
Full textBenaceur, Amina. "Réduction de modèles en thermo-mécanique." Thesis, Paris Est, 2018. http://www.theses.fr/2018PESC1140/document.
Full textThis thesis introduces three new developments of the reduced basis method (RB) and the empirical interpolation method (EIM) for nonlinear problems. The first contribution is a new methodology, the Progressive RB-EIM (PREIM) which aims at reducing the cost of the phase during which the reduced model is constructed without compromising the accuracy of the final RB approximation. The idea is to gradually enrich the EIM approximation and the RB space, in contrast to the standard approach where both constructions are separate. The second contribution is related to the RB for variational inequalities with nonlinear constraints. We employ an RB-EIM combination to treat the nonlinear constraint. Also, we build a reduced basis for the Lagrange multipliers via a hierarchical algorithm that preserves the non-negativity of the basis vectors. We apply this strategy to elastic frictionless contact for non-matching meshes. Finally, the third contribution focuses on model reduction with data assimilation. A dedicated method has been introduced in the literature so as to combine numerical models with experimental measurements. We extend the method to a time-dependent framework using a POD-greedy algorithm in order to build accurate reduced spaces for all the time steps. Besides, we devise a new algorithm that produces better reduced spaces while minimizing the number of measurements required for the final reduced problem
Hadji-Ristic, Daniel Ilan. "Thermo-electric and transport properties of etched quantum point contacts." Thesis, Royal Holloway, University of London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444164.
Full textPantuso, Daniel. "A finite element procedure for the analysis of thermo-mechanical solids in contact." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/10441.
Full textSrirattayawong, Sutthinan. "CFD study of surface roughness effects on the thermo-elastohydrodynamic lubrication line contact problem." Thesis, University of Leicester, 2014. http://hdl.handle.net/2381/29057.
Full textNikas, Georgios. "Theoretical modelling of the entrainment and thermomechanical effects of contamination particles in elastohydrodynamic contacts." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314006.
Full textBausseron, Thomas. "Etude de l’échauffement de la caténaire lors du captage à l’arrêt : Développement d’un outil informatique." Thesis, Besançon, 2014. http://www.theses.fr/2014BESA2062/document.
Full textIn the railroad and trains domain, many incidents show the main problem of overheating of the catenary at the contact with the pantograph when the train was stopped whereas all the electrical systems of the train should nevertheless be fed. Analysis of these incidents has shown that the overheating of the interface catenary-pantograph during the ream conditioning was sometimes at the origin of the break of the contact wire. In order to forecast such very expensive problems for the company, the French National Railway Company (SNCF) and the research institute FEMTO-ST carried out theoretical and experimental studies to better understand this phenomenon. First a quasi 3D transient electrothermal modeling tool has been developed for the contact wire. It has also permitted to estimate the distribution of current in the wire in order to obtain the internal heat power generation. An electrothermal modelisation of the strip complete the system. Finally the heat transfer equation in the wire with particular boundary conditions has been solved in all the finite differences network thanks to the Euler's implicit method
Doyen, Franck. "Comportement tribologique du contact sec arbre acier - paliers carbonés avec butées soumis à des sollicitations thermo-vibratoires sévères." Poitiers, 2006. http://www.theses.fr/2006POIT2344.
Full textThe tribology of the dry contacts subjected to relative displacements of low amplitude and the friction materials are themes which are regularly treated in the literature. However, the studies referring simultaneously of both are very rare. The purpose of this manuscript is to improve comprehension of the physical phenomena and the tribological behavior inherent to the dry contacts “shaft / bearing with thrust” subjected to a thermo-vibratory environment. The industrial mechanism on the origin of this study was analyzed in order to identify its principle and these operating conditions. A diagnosis on its losses of functionalities, the link between its disfonctionnements and the studied contact, and a morphological expertise of its guidance elements were performed. A new experimental test rig was designed and realized in order to reproduce the real contact conditions of the studied guidance elements (concept of “tribological triplet”). Its various elements and the steps followed to validate its functionalities are exposed. Thanks it, for the various studied material couples, significant experimental results on their wear (and its physical phenomena) and their capacity of velocity accommodation are obtained. The contribution of a 3D numerical model integrating a misalignment for a cylinder in cylinder contact was detailed and analyzed. A scientific synthesis discussing the influence of the size of graphites grains, the nature and the orientation of composites, but also the origin of the identified physical phenomena (the migration of the impregnated elements, the presence of rectangular forms in the contact zones) is carried out
Feral, Hervé. "Modélisation des couplages électro-thermo-fluidiques des composants en boîtier press-pack : application à l'Integrated Gate Commutated Thyristor 4,5kV-4kA." Toulouse, INPT, 2005. http://ethesis.inp-toulouse.fr/archive/00000220/.
Full textTemperature is an important parameter when you use semi-conductors. In the multi MW power converters the semiconductor losses are upper than kW. The thermal analyzes of the semiconductor package and cooling system must be performed to understand the thermal limitations. The maximal temperature can not be upper than 150°C for silicium components. The temperature variations have an impact on the component life time
Murer, Yann. "Établissement de modèles prévisionnels du comportement thermo-acoustique de structures composites multicouches et sandwichs." Toulouse, ENSAE, 1998. http://www.theses.fr/1998ESAE0022.
Full textSeitz, Alexander [Verfasser], Wolfgang A. [Akademischer Betreuer] Wall, Wolfgang A. [Gutachter] Wall, and Yves [Gutachter] Renard. "Computational Methods for Thermo-Elasto-Plastic Contact / Alexander Seitz ; Gutachter: Wolfgang A. Wall, Yves Renard ; Betreuer: Wolfgang A. Wall." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/1182536344/34.
Full textMaillet, Anaïs. "Interactions argilite de Tournemire / fer métal en contexte in situ : résultats à 10 ans de contact." Thesis, Poitiers, 2012. http://www.theses.fr/2012POIT2309/document.
Full textWithin the framework of a long lived radioactive waste storage concept in deep geological layer developed by Andra, IRSN leads an in situ study on the Experimental Station of Tournemire, in association with EDF to determine the interactions steel/argillite in a natural context. After 10 years of interaction, two drillings overcoring performed to characterize the processings of the Tournemire argillite in contact with carbon and stainless steels and to compare reactive phenomena highlighted and those induced by simulations tools combining chemistry and transport.Argillite/carbon steel samples show a significant corrosion of steel disk. Iron released, in the form of rings and cracks in the rock, disrupts the argillite in contact resulting in mineralogical and structural changes. Iron oxides precipitation and a calcite and smectitic leaf of mixed-layers I/S dissolution are identified. A succession of areas: metal/metal corroded/argillite disturbed/argillite is highlighted and porosity variations are observed on the interfaces between two areas. Geochemical simulations show that major changes are initiated speedly during establishment of the system and the oxygen trapped in the closed system is consumed by the corrosion of steel but mostly it diffuses into the surrounding material through concentration gradient.Argillite/stainless steel samples have a very low pitting corrosion of steel disk. This does not seem to affect the mineralogy of the argillite in contact
Gallino, Stéphanie. "Hydrogéologie, géochimie et modélisation hydrodynamique-thermique d'un système thermo-minéral associé à un contact structural alpin (Aix-les-Bains - Savoie)." Chambéry, 2007. http://www.theses.fr/2007CHAMS039.
Full textThis study, based on a interdisciplinary approach, re-examines the circulation model of the thermal and mineral waters from Aix-les-Bains for drilling a rescue well. A 3D model, built from geological and geophysical data, shows that two major faults (N135 and N065°E) individualize the three studied sites (Thermes Nationaux, Thermes de Marlioz, Raphy Saint Simon). Hydrochemical data suggest a millennial residence time for the waters, a major role of the thrust in the main mineralisation (Na, K, C1, SO4), a strong link between the chemical characteristics of each site and the exchange ionic processes evolution during the upwelling and a mixing with the surface waters in the final part of the upwelling. The mineral waters have a different sulphate origin compared with the thermal waters (pyrite or triassic gypsum dissolution). The hydrodynamical data demonstrates that (i) the Valanginian and the Kimmeridgian limestones represent the infiltration zones, (ii) the starting of the well exploitation catches deep flows towards the springs and (iii) the dispersive role of the urgonian karst in the final upwelling. The coupled hydrodynamical-thermical model evidences the cooling of the thermal waters in deep depth. The current temperatures are induced by an un-steady state flow since the last deglaciation. An evolution in time and space of the hydraulic conductivities (initiation and evolution of the karst), and/or a late starting of the hydrothermal system (tills leaching, neotectonic event) is then needed
McBride, Diane. "Vertex-based discretisation methods for thermo-fluid flow in a finite volume-unstructured mesh context." Thesis, University of Greenwich, 2003. http://gala.gre.ac.uk/6246/.
Full textChen, Chi. "2-D Finite Element Modeling for Nanoindentation and Fracture Stress Analysis." Scholar Commons, 2009. https://scholarcommons.usf.edu/etd/1897.
Full textMaghsoodi, Soheib. "Thermo-mechanical behavior of soil-structure interface under monotonic and cyclic loads in the context of energy geostructures." Electronic Thesis or Diss., Université de Lorraine, 2020. http://www.theses.fr/2020LORR0031.
Full textIncorporation of heat exchangers in conventional geostructures like piles can extract the heat from the soil for heating purposes and inject it to the soil for cooling purposes. In recent years, research has been conducted at full and laboratory scale to investigate the effect of temperature on the geotechnical behavior of these energy geostructures as well as on the surrounding soil. Indeed, these energy geostructures can be subjected to cyclic mechanical loads and thermal variations throughout their lifetime. The aim of this study was to deepen the understanding regarding the behavior of sand/clay-structure contact under complex thermo-mechanical loads. A temperature-controlled direct shear device to perform monotonic and cyclic constant normal load or constant normal stiffness tests was developed. The response of the interface to the thermal effects on the mechanical behaviour of soils and soil-structure interface was investigated. Fontainebleau sand and kaolin clay were used as proxies for sandy and clayey soils. The results showed that the applied thermal variations have a negligible effect on the shear strength of the sand and sand-structure interface. In clay samples the temperature increase, increased the cohesion and consequently the shear strength, due to thermal contraction during heating. The adhesion of the clay-structure interface, was less than the cohesion of the clay samples. To investigate the mechanical cyclic load effects on the clay-structure interface at different temperatures, monotonic and cyclic constant-volume equivalent-undrained direct shear tests were performed on clay-clay and clay-structure interface at different temperatures. The results showed that, the number of cycles to failure for the clay-structure interface test was lower than that for the clay-clay case in the same range of cyclic and average shear stress ratios. Increasing the temperature, decreased the rate of strain accumulation and the number of cycles to failure increased by 2-3 times. The rate of degradation (degradation parameter, t) decreased by 16% with heating from 22 to 60oC for the different cyclic stress ratios tested. A non-isothermal soil-structure interface model based on critical state theory was then developed. The non-isothermal model takes into account the effect of temperature on the void ratio of interface prior to shearing. The model is capable to capture the effect of temperature on soil-structure interface under constant normal load and constant normal stiffness conditions for both sandy and clayey interfaces. The additional parameters have physical meanings and can be determined from classical laboratory tests. The formulation is in good agreement with the experimental results and the main trends are properly reproduced
Garcia, Mathieu. "Refrigerant-lubricated gas foil bearings : A thermo-hydrodynamic study (application to rigid bearings)." Thesis, Lyon, INSA, 2012. http://www.theses.fr/2012ISAL0133/document.
Full textInternal experiments at Liebherr-Aerospace FRANCE on new refrigerant-lubricated compressor designs have shown that under specific operating conditions, a mixture of vapor and liquid appears in the compressor, instead of a single-phase vapor flow. Therefore, refrigerant-lubricated foil bearings behavior is studied, including the likelihood of two-phase flow in the lubricant. We focus on the lubricant behavior only, in the operating conditions of foil bearings. The Thermo-Hydrodynamic approach describes lubricant characteristics such as pressure, density, viscosity, and temperature. It involves the use of a generalized Reynolds equation for turbulent flow, a nonlinear cubic equation of state for two-phase flow and a 3D turbulent thin-film energy equation. Journal bearing global parameters are calculated for steady-state conditions
Romano, Mungaray Marta. "Development of a non contact calorimeter in isoperibolic millifluidic systems using InfraRed Thermography : applied to biphasic flows." Thesis, Bordeaux 1, 2013. http://www.theses.fr/2013BOR14886/document.
Full textThis work concerns the development of a non-contact calorimeter for two-phase flow characterization. The biphasic flow is performed under a droplet configuration inside millimetric tubings which are inserted into the isoperibolic chip. The main idea is to combine the Infrared Thermography and microfluidic tools to propose a suitable technique for accurate measurements. Microfluidics enables the use of small reaction volumes thus limiting any risk of dangerous reactions inside droplets, the Infrared tool enables to monitor the thermal signature of these flows with high accuracy. The results of this thesis show that this tool is able to estimate the thermophysical properties of non-reactive flows. Also , it is possible to characterize chemical reactions in terms of enthalpy and kinetics . Finally the latter characterization was compared to conventional techniques to demonstrate the benefits and the precision of the tool
Meinshausen, Lutz. "Modelling the SAC microstructure evolution under thermal, thermo-mechanical and electronical constraints." Thesis, Bordeaux, 2014. http://www.theses.fr/2014BORD0149/document.
Full textA further miniaturization of microelectronic components by three dimensionalpackaging, as well as the use of microelectronic devices under harsh environmentconditions, requires the development of more robust alternatives to the existing Snbased solder joints. One promising technique is the diffusion and migration driventransformation of conventional solder bumps into intermetallic compound (IMC)connections. The related process is called transient liquid phase soldering (TLPS).Against this background an investigation of the IMC formation under consideration ofelectromigration and thermomigration was performed. For the stress tests Packageon Package structures are used. The final result is a general model for the IMCformation in solder joints. Combined with a Finite Element Analysis (FEA) this modelis used to predict the IMC formation in solder joints for a broad range of boundaryconditions. In future the model of the IMC formation can be used to optimize a TLPSprocess
Mikula, Martin. "Termodiagnostika - dotykové a bezdotykové měření teploty." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2014. http://www.nusl.cz/ntk/nusl-231525.
Full textSobac, Benjamin. "Evaporation de gouttes sessiles : des fluides purs aux fluides complexes." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM4801/document.
Full textThis thesis presents an experimental study on the evaporation of droplets on a solid substrate. In the first part we describe the evaporation of a liquid droplet, taking a particular interest in the influence of the substrate. The problem is approached from a new angle by ensuring that the various properties of the substrate, such as its roughness, surface energy and thermal properties, are controlled precisely. Thanks to this method it is possible to decouple the different influences of the substrate and to study evaporation in relation to various dynamics of triple lines and a wide range of contact angles, thermal conductivities and temperatures of the substrate. Experimental results are compared with the classic evaporation model, which considers evaporation as a process determined by the diffusion of vapor into the atmosphere. The study reveals the range of validity of this model and highlights the different additional mechanisms which may develop as well as their contribution. The use of an infrared camera reveals the development of a complex hydrodynamic non-axisymmetric pattern. The origin of this instability and its spatial and temporal dynamics are also explored. In the second part, the study is extended to the evaporation of a dropl of a biological suspension: human blood. As this fluid dries a complex pattern is formed which is dependent on the wettability of the substrate. Whereas a wetting situation leads to a ring-like deposit with radial cracks, a non-wetting situation reveals a complex shape composed of cracks and folds. The study focuses on the understanding of the physical mechanisms leading to these patterns and of the role of biology
Mora, Anne-Sophie. "Élaboration de revêtements époxy pour contact alimentaire à empreinte environnementale réduite A perspective approach on the amine reactivity and the hydrogen bonds effect on epoxy-amine systems vanillin-derived amines for bio-based thermosets synthesis of biobased reactive hydroxyl amines by amination reaction of cardanol-based epoxy monomers synthesis of pluri-functional amine hardeners from bio-based aromatic aldehydes for epoxy amine thermosets cardanol-based epoxy monomers for high thermal properties thermosets." Thesis, Montpellier, Ecole nationale supérieure de chimie, 2019. http://www.theses.fr/2019ENCM0012.
Full textThe presented PhD works were initiated by an industrial collaboration with the company Nouvelle Sogatra, specialized in the design, manufacturing and marketing of two component protective coatings for food contact. The aim of this project is to offer new high-performance epoxy thermosets from bio based reactants and, ideally with a low impact on the health and the environment. This PhD works focus on the identification of new synthesis methodologies of bio-based amine hardeners, which could be easily industrialized.The direct epoxy amination by ring opening using ammonia and the reductive amination via imine synthesis were selected as synthesis routes for their simple utilization and their eco friendly character. Hence, bio based and/or reduced toxicity commercial precursors were selected. New amine hardeners were synthesized from bio resources, such as vanillin, cardanol and benzaldehyde. These hardeners were then used to synthesize epoxy-amine thermosets, whose thermomechanical and physicochemical properties were characterized
Höer, Martin. "Einfluss der Material- und Verarbeitungseigenschaften von Phenolharzformmassen auf die Qualität spritzgegossener Bauteile." Doctoral thesis, Universitätsbibliothek Chemnitz, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-155078.
Full textInjection moldable thermosetting materials show excellent material properties, e.g. high thermo-mechanical resistance and reduced shrinkage in combination with low material cost. Thus, technical requirements for high performance parts for automotive applications can be achieved. In the scope of this work different phenolic novolac compounds were investigated regarding their hygroscopic behavior with its influence for injection molding and product quality. The absorption can be approximately described by Fick’s-Diffusion-Model. The interrelationship of injection molding parameters and the thermo-mechanical behavior is examined on the basis of mechanical testing and the assessment of the dimensional accuracy for a thermoset high precision part. The presented investigations point to the limit of processing and realizable part quality which can be transferred for high performance parts molded in mass production
Abdul-Hussain, Najlaa. "Experimental Study on the Engineering Properties of Gelfill." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/19852.
Full textMárquez, Costa Juan Pablo. "Caractérisation et modélisation des interfaces dans les composites organiques stratifiés à haute température : Application à la tenue au feu des structures aéronautiques PhyFire LOT 2 - Développement de modèles de comportement du composite Caractérisation en température de la ténacité en mode II des interfaces des CMO en utilisant l’effet Joule Caractérisation du comportement visqueux des interfaces CMO et influence sur la propagation de délaminage Convention PhyFIRE 2 - LOT 2 : Développement d’un cadre de modélisation pour les matériaux composites Durabilité des matériaux composites en conditions extrêmes : vers la prédiction des propriétés de tenue au feu Durability of Composite Materials under Severe Temperature Conditions : Influence of Moisture Content and Prediction of Thermo- Mechanical Properties During a Fire Towards the Prediction of Sandwich Composites Durability in Severe Condition of Temperature : A New Numerical Model Describing the Influence of Material Water Content during a Fire Scenario." Thesis, Chasseneuil-du-Poitou, Ecole nationale supérieure de mécanique et d'aérotechnique, 2021. http://www.theses.fr/2021ESMA0004.
Full textWithin the framework of the fire resistance of composite materials, it is necessary to assess the degradation of their thermal and mechanical properties due to mass losses, matrix cracking and/or delamination cracks. Nevertheless, few studies in the literature about the temperature resistance of aeronautical composites concern the mechanical behaviour and the rupture of interfaces before any thermal degradation,subject which is the main topic of this work. Thus, the objective is to propose a failure model concerning both the delamination crack initiation and growth under thermomechanical loads. Much of this work has focused on the characterisation of interface properties using an analysis of mode II crack propagation tests for Joule heated specimens. These numerical analyses show that the ply behaviour does not explain the macroscopic pseudo-ductile response observed experimentally. Thus, a test-calculation dialog method, comparing the kinematic fields measured by digital images correlation and those simulated by finite elements, underlines the importance of the viscous behaviour at the interface scale. By a similar FEMU approach the parameters of a cohesive-type fracture law have been identified in temperature and taking into account the different sources of uncertainty. This work highlights the similarity between plane and out-of-plane shearing, both on behaviour and on failure. In parallel, the analysis of temperature resistance tests by laser impact made it possible to establish a crack initiation criterion by a coupled stress and energy approach. A comparison of this criterion with the parameters of the cohesive zone law previously identified makes it possible to discuss about the modeling scale of the interface
Fortin, Marie-Chantale. "Études psychophysiques de la mémoire à court terme de la douleur expérimentale." Thèse, 2004. http://hdl.handle.net/1866/15760.
Full textGeyn, Sergey [Verfasser]. "FEM-BEM procedures for elastoplastic thermo-viscoplastic contact problems / von Sergey Geyn." 2007. http://d-nb.info/984384472/34.
Full textShanthraj, Pratheek. "Electro-thermo-mechanical modeling of metal to metal contact RF MEMS switches." 2008. http://www.lib.ncsu.edu/theses/available/etd-11072008-132844/unrestricted/etd.pdf.
Full textFang, Chining-Lining, and 方志亮. "A Study on Contact Problem for Rolling by Three-Dimensional Thermo-Coupled Model." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/98040673953021231403.
Full text國立臺灣科技大學
機械工程研究所
84
In this paper, a coupled thermal elastic-plastic finite element model with three-dimensional strip rolling is derived. The roller is assumed to be elastic and the transient heat transfer is considered. The elastic deformation and thermal expansion amount on the contact face are calculated during the strip rolling process to derive the iteration method of the corresponding final deformation of the roller and the strip by means of the same shape functions. Distribution of the roller elastic deform ation and thermal expansion amount during the rolling process was also explored. The effect of the said distribution of deformation amount on the strip shape after roller is analyzed. The purpose is to verify that controlling the surface shape of the roller axial cross section can effectively improve the smoothness of strip surface. In terms of strips, the large deformation-large strain theory, the update Lagrangian formulation and incremental principle were used in this paper to develop the three dimensional thermal elastic plastic analytical model of aluminum strip rolling. The flow stress was considered as the function of strain, strain rate and temperature. The three-dimensional transient heat transfer is then derived and is integrated with the contact model among rollers. Thus ,a coupled thermal elastic plastic finite element model is established. It can predict the contact force and contact deformation amount between elastic rollers and elastic-plastic strips.
Leong, Hoi Liong, C. L. Gan, Kin Leong Pey, Carl V. Thompson, and Hongyu Li. "Effects of Applied Loads, Effective Contact Area and Surface Roughness on the Dicing Yield of 3D Cu Bonded Interconnects." 2005. http://hdl.handle.net/1721.1/29818.
Full textSingapore-MIT Alliance (SMA)
Chang, Yu-Hsuan, and 張羽萱. "The Manufacture of Nanofibers that Contain Thermo-Sensitive Carriers and the Study of Drug Release." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/7nt2k6.
Full text嘉南藥理大學
化粧品應用與管理系
102
In this study,the polystyrene latex particles with different size were Synthesized. Afterward, the polystyrene latex particles were mixed with Poly(N-isopropylacrylamide-co-N-methylol acrylamide(poly(NIPAAm-NMA))to from the methanol polymer solution,and then was electrospun to from the manofiber , Moreover, the poly(Methyl methacrylate-Methyl acrylic acid)/Poly(N-Isoproplyacrylamide- Methyl acrylic acid),dense latex particles and poly(N-Isoproplyacrylamide- Methyl acrylic acid)hollow latex pareicles were mixed with Poly(N-isopropylacrylamide-co-N- methylolacrylamide(poly(NIPAAm-NMA)) to form the methanol polymer solution respectively, and then was electrospun to form the nanofiber, The properties and the of the caffeine nanofibers were studied in this article.
Lin, Ying Mei, and 林盈湄. "The manufacture of nanofibers that contain thermo-sensitive carriers and liposome and their application in drug release." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/kf4ya7.
Full text嘉南藥理大學
化粧品應用與管理系
103
In this study, the model drug was encapsulated inside the thermos-sensitive polymer carriers and liposome respectively, and was manufactured to form the nanofiber by a special spinning method. The behavior of the drug released from the nanofiber was investigated in this study. This study included two parts, the first part was to manufacture the liposome. In this study, the first part was to manufacture the liposome by using the lipid was materials. Besides, the effect of various variables on the properties of liposome were investigated. The liposomes were stored in the condition of difference temperature for 30 days to study the stability of particles size. The results showed that the addition of cholesterol might enhance the stability of liposome. The second part was to manufacture the thermos-sensitive polymer particles with hollow structure. The model drug was encapsulated inside the hollow zone of the polymer particles. The TEM and dynamic laser light scattering were used to study the morphology and particle size of the hollow polymer particles that loaded with model drug respectively. Moreover, the liposome and hollow polymer particles were manufacture to form the nanofiber, and the properties of the fiber were studied.