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Dissertations / Theses on the topic 'Thesis (PhD.) – Western Sydney University, 2019'

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Published: 20 February 2023

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1

"Performance enhancement of PowerWindow, a linear cascade wind turbine, for application in urban environments." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56569.

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Urban environments have many attractions and difficulties when it comes to the development of wind energy harvesting systems. Critical issues of using these systems in urban environments include noise, aesthetics, integration into architectural systems, and efficient use of the available wind resource. Wind in urban areas tend to be more turbulent and multi-directional. The presence of buildings increases the turbulence of the wind and also deflects the direction of the wind from a horizontal free stream. Aesthetics is also a concern as many people find conventional wind turbines unattractive.
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2

Dabral, Deepti. "Dissecting the role of phospholipase A2 in the late stages of regulated exocytosis." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53851.

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This thesis is divided into five chapters. The overarching working hypothesis is published as a ‘perspective’ article in International Journal of Biochemistry and Cell biology, 2017 https://doi.org/10.1016/j.biocel.2017.01.011 and is also discussed in the last section of Chapter - 1. Hence, there are similarities in the published article and sections of Chapter - 1. The working hypothesis states that endogenous PLA2 near docking/ fusion sites provide basal levels of LPC that acts as a ‘molecular brake’ against spontaneous fusion, and FFA that aids in trans-SNARE complex formation to ensure eff
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3

Dunn, James S. "Experimentally induced musculoskeletal pain : a tool for understanding chronic pain." Thesis, 2019. http://hdl.handle.net/1959.7/uws:58276.

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Pain is a complex modality which can arise from a plethora of sources, both internal and external, which, under normal physiological conditions, is an essential aspect of life for the identification of injury to an individual. However, in a subset of the population suffering from chronic pain, the distinction between painful and non-painful sensations can become askew, resulting in the formation of allodynia, hyperalgesia and other manifestations of pain-hypersensitivity. Within this thesis, the utilisation and characterisation of both acute and prolonged experimental models of musculoskeletal
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4

Galvin, Timothy J. "The radio continuum emission of star forming galaxies at low to high redshift." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56423.

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In this thesis, the radio-continuum emission of starburst galaxies is explored to understand the physical processes that trace star formation. Separating and constraining these processes require a broad, densely sampled spectral energy distribution that can be used to apply and constrain various radiative transfer models. Existing tracers of star formation include a suite of multi-wavelength diagnostics, including UV, optical, infrared, nebular transitions, and radio continuum. At present, optical and near infrared observations have been the most successful at probing the high redshift volume
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5

Law, Rebecca K. "Seculum, an epic trilogy in verse by Peter Dale Scott : the poem as structure for a new dawn." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56670.

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This dissertation reads the three books of Canadian-American poet and scholar Peter Dale Scott’s epic poem Seculum. Scott identifies as a practising Buddhist with a strong interest in Catholic theology and his poetry explores key ideas associated with both systems of belief. I argue that Scott formally employs the number three in diverse ways within the trilogy and that this formula (as in the poetic tercet form) constructs a poesis that is structured on the ruins of a type of Dantean Hell. Similarly, that this repetition gradually replaces the characteristics of Hell – such as darkness and fe
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6

Ching, Shimin (April). "The role of conscious and nonconscious processes in multimodal representation formation." Thesis, 2019. http://hdl.handle.net/1959.7/uws:58369.

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That subjective experience is a unified and multisensory whole suggests that multisensory integration may have a critical role to play in the generation of consciousness. This relationship has been formalised in several theories, the most influential being Global Workspace Theory (GWT; Baars, 1988). GWT posits a modular sensory processing system in which sensory inputs are processed in sequestered modality- or feature-specific networks; interaction between modules is only possible if their contents are globally broadcast throughout the brain via long-range connections (i.e., the global workspa
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7

Bressan, Alessandro. "Environmental and social responsibility within SMEs : managerial perspectives from Western Sydney, Australia." Thesis, 2014. http://handle.uws.edu.au:8081/1959.7/uws:31714.

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SMEs in the Western Sydney Region operate in a complex and competitive environment and are an integral part of the community in which they are based. They provide employment in the region and are also significant drivers for the growth, development and maintenance of the Western Sydney economy. It is not known nevertheless the extent to which these SMEs practice environmental and social responsibility (ESR). In order to address this knowledge gap, this thesis investigates the relationship between micro, small and medium-sized enterprises (SMEs), and ESR. More specifically, through a combinati
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8

Raposo, Anita E. "Characterising protein arginine methylation in glioblastoma cell lines : implications for brain cancer." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53102.

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Protein arginine methylation is a post-translational modification that plays important roles in cellular signalling, transcription and RNA splicing and transport. The enzymes responsible for arginine methylation, protein arginine methyltransferases (PRMTs), have been reported to be aberrantly expressed in a variety of cancers, including breast, lung, bladder, prostate, ovarian and mantle cell lymphoma. It has become evident that arginine methylation is also a regulator of the cell cycle and aberrant expression of PRMTs contributes to deregulation of the cell cycle, contributing to carcinogenes
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9

Castaneda-Gomez, Laura. "Soil organic matter dynamics under elevated CO2 : mechanisms of impact." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54453.

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Soil carbon (C) is one of the most relevant reservoirs of this element on Earth and plays a critical role in climate regulation. The effects of rising atmospheric carbon dioxide (CO2) concentrations on soil C cycling and soil C stocks have been extensively investigated but the mechanisms by which the impact eCO2 may be altered are still not well understood. This is hindering our capacity to improve the predictions of the fate of C stocks and further impacts on climate change. In this thesis, I explored different mechanisms mediating the impact of eCO2 on SOM dynamics accounting for effects on
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10

Abuorabi, Yousef. "Skills of forensic accountants as expert witnesses and admissibility of expert testimony." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56773.

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The demand for accounting expert witness services has increased over the past decade, as has the diversity of areas that expert witnesses are required to cover. Consequently, many universities and colleges are currently considering adding forensic accounting courses to their curriculum (Wang et al. 2016, DiGabriele 2010). Identifying appropriate forensic accounting skills will aid both academia and professional bodies to integrate these skills into their accounting curriculum (Bhasin 2016). This will help accounting students of tertiary institutions and professional bodies gain appropriate for
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11

Singh, Gursharan K. "Access and referral to palliative care for individuals with chronic heart failure." Thesis, 2019. http://hdl.handle.net/1959.7/uws:58320.

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Background: Chronic heart failure is associated with poor survival rates and high symptom burden. Despite recommendations for palliative care to improve symptoms and quality of life for individuals with chronic heart failure, palliative care remains underutilised by individuals with chronic heart failure. Purpose: This thesis examines patient, provider and system factors influencing access and referral to palliative care for individuals with chronic heart failure. Methods: This was a mixed-methods study encompassing a survey, a meta-synthesis and qualitative semi-structured interviews. Results
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12

Kamara, Joseph K. "Examining drought resilience in Eswatini and Lesotho." Thesis, 2019. http://hdl.handle.net/1959.7/uws:58317.

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This thesis explores drought resilience and the well-being of rural communities of southern Africa. The region is vulnerable to the negative effects of recurrent droughts, which erode development gains and continuously degrade the capacity of communities to withstand, absorb, adapt and recover from recurrent drought hazards. Drought occurrences have increasingly intensified in severity across the region, resulting in catastrophic effects. Two of the most drought-prone countries in southern Africa are the land-locked Kingdoms of Lesotho and Eswatini, where the majority of the population live in
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13

Inampudi, Vamsi. "Investigations on the protective role of low-to-moderate alcohol consumption on high fat diet-induced non-alcoholic fatty liver disease." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54126.

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The proposed research project is based on the hypothesis that long-term low and moderate alcohol protects the liver from progression to NAFLD. The general objective of this thesis is to investigate the in vivo and in vitro effects of alcohol on NAFLD induced by HFD-fed rat model. The specific objectives of this thesis are (i) To elucidate the serum and histopathological changes observed by alcohol treatments on in vivo model, (ii) To elucidate the possible mechanism(s) of action of low and moderate alcohol on controlling HFD-induced NAFLD in the liver, (iii) elucidate the possible mechanism(s)
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Shabanivaraki, Elham. "Hemodynamic monitor for rapid, cost-effective assessment of peripheral vascular function." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54129.

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Worldwide, at least 200 million people are affected by peripheral vascular diseases (PVDs), including peripheral arterial disease (PAD), chronic venous insufficiency (CVI) and deep vein thrombosis (DVT). These diseases have considerable socioeconomic impacts due to their high prevalence, cost of investigation, treatment and their effects on quality of life. PVDs are often undiagnosed with up to 60% of patients with PVD remaining asymptomatic. Early diagnosis is essential for effective treatment and reducing socioeconomic costs, particularly in patients with diabetes where early endovascular tr
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Mueller, Robert. "Characterisation of fungal symbionts and microbial communities of Austroplatypus incompertus (Platypodinae) and other Australian ambrosia beetle species." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56997.

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Insects are the most diverse taxonomic class and live often in a tight symbiotic associations with a microbial cosmos that is expected to be even more diverse. One of these symbioses is fungal farming, the ability to propagate, cultivate and harvest fungi as a primary food source. This ability evolved independently in three major insect orders, attine ants, macrotermitine termites and ambrosia beetles. While many studies have been conducted on the former two orders, the diversity and mechanisms of fungal farming in ambrosia beetles are less understood. Ambrosia beetles include two subfamilies,
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16

Knight, Gerold C. "Crisis management : aligning scripts and actors : strengthening crisis response capabilities by minimising process deviation." Thesis, 2019. http://hdl.handle.net/1959.7/uws:52940.

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The present business resilience paradigm has expanded to embrace the processes and routines employed by a business to remain viable, sustain growth and recover (if required) in what for many people has become a complex global operating environment. Sutcliffe (2003, p. 2) defines resilience as “the maintenance of positive adjustment under challenging conditions” and the combination of proactive routines such as enterprise risk management and reactive routines such as crisis management create the overarching umbrella of business resilience. Whether they are proactive or reactive, ostensive rout
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17

Sagun, Julius V. "Environmental regulation of energetics of C4 photosynthesis." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54242.

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Many studies have been aimed at understanding the biochemistry and significance of C4 pathway since its discovery. It has become well established that this pathway enables the plant to photosynthesize at a higher rate than C3 photosynthesis under conditions of high temperatures and limited water supply. This is because of the CO2 concentrating mechanism (CCM) in C4 photosynthesis achieved by a series of anatomical and biochemical adaptations which allow the operation of two photosynthetic cycles, C4 and C3, across the outer mesophyll (MC) and inner bundle-sheath cells (BSC) to saturate Rubisco
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Fanna, Daniel J. "Metal directed supramolecular assemblies for optical materials : chemosensor design and application." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53225.

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This dissertation reports the design, synthesis and characterisation of several metallosupramolecular assemblies incorporating 8-hydroxyjulolidine-9-carboxaldehyde or 4- (diethylamino)salicylaldehyde groups. These groups are well known as strong electron donors, and as such, they are potentially favourable for the development of electro-optical materials, especially chemosensors. Furthermore, the presence of their aldehyde functional group makes these moieties ideal for condensation reactions with primary amines, and the resulting imine (chapter 2-4) or dihydropyrimidine (chapter 5-7) groups a
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19

Dong, Ke. "Development and quality evaluation of bioactive rich drink powder based on sea buckthorn." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54363.

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Sea buckthorn berries have been used as an ancient medicine for thousands of years. Exceptional nutritional value and health benefits of sea buckthorn have been disclosed by recent research. Sea buckthorn berries are high in health-enhancing bioactive compounds. The major health benefits of sea buckthorn include anti-oxidation activities, anti-cancer properties, reduction of cardiovascular disease and improvement of immune system. Evidence suggests that diets rich in antioxidants reduce the risk of Alzheimer’s disease (AD) through direct effects on amyloid beta (Aβ, a hallmark of AD) and conse
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Lotfi, Fezeh. "The low energy consumption forward osmosis desalination process." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53967.

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Recently, there have been efforts to develop alternative desalination technologies that operate at low or no hydraulic pressure and potentially reduce the capital and operation costs. Forward osmosis (FO) process has emerged as one of the most promising candidates for desalination with a potential to consume much lower energy than the conventional processes depending on the types of applications. The main objective of this study is evaluating a suitable and practical application as a low energy desalination technology for irrigation and fresh water. The following are some of the specific objec
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Malik, Khalida. "Pembea kazi (career seesaw) for Kenyan Asians in Australia : capital mobilisation in skilled migrants’ career experiences." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53118.

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Skilled migrants are a valuable form of labour vital to the economic growth of many Western industrialised nations, including Australia. The dominant perspective in the research scholarship has been to understand the experiences of skilled migrants using the human capital approach that views them as economic agents. This perspective ignores the importance of other capitals implicated in skilled migrants’ career experiences. Bourdieu’s (1986) construct of capitals and his earlier work in Algeria is utilised in this study revealing insights that strongly suggest skilled migrant career experience
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Bowcock, Nerissa L. "Investigating the role of DNA methylation in coeliac disease." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56290.

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Coeliac disease (CD) is a chronic autoimmune disease characterised by mucosal inflammation in the small intestine in response to dietary gluten in genetically susceptible individuals. Current screening and diagnostic tests for CD are suboptimal as accurate serology and histology requires active consumption of gluten. Additionally the gastroscopy procedure is invasive and carries risks associated with anaesthesia and oesophageal perforation. Furthermore, genetic testing for CD susceptibility is only useful for its negative predictive value, as up to 56% of the Australian general population carr
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23

Colley, Ian. "Visual cues in musical synchronisation." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54570.

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Although music performance is generally thought of as an auditory activity in the Western tradition, the presence of continuous visual information in live music contributes to the cohesiveness of music ensembles, which presents an interesting psychological phenomenon in which audio and visual cues are presumably integrated. In order to investigate how auditory and visual sensory information are combined in the basic process of synchronising movements with music, this thesis focuses on both musicians and nonmusicians as they respond to two sources of visual information common to ensembles: the
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Kumarathunge, Dushan. "Predicting the effect of temperature on tree growth." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53574.

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Temperature plays a key role in plant growth and development, because it affects metabolic rates of every physiological process. With growing concern over global warming, the responses of forests to increasing temperature has become an important topic in recent decades. If we are to predict the fate of global forests in a future warmer world, we need to understand and quantify the mechanisms of the temperature response of plant growth. Predictions of global warming impacts on forest growth are widely made using terrestrial biosphere models. Terrestrial biosphere models use environmental data a
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Petersingham, Gayani. "Characterisation of metal-amyloid β peptide interactions and the effect of metals on the gene expression of amyloid precursor protein". Thesis, 2019. http://hdl.handle.net/1959.7/uws:60008.

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AD is a devastating neurodegenerative condition that poses major challenges to human health, with a prevalence of around 35 million patients worldwide. One of the neuropathological hallmarks in AD patients is extracellular amyloid plaques which are composed of amyloid β peptide (Aβ) aggregates. The amyloid cascade hypothesis suggests that aggregation of the Aβ peptide into soluble oligomers and senile plaques is the main driver of AD. Metal ions are found to be present in amyloid plaques, including Cu2+, Fe2+/3+, Zn2+ and Al3+. The experimental evidence from the literatures thus far points to
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Riley, Rohan C. "Towards a predictable framework of mycorrhizal phenotypes under environmental stress." Thesis, 2018. http://hdl.handle.net/1959.7/uws:54359.

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The arbuscular mycorrhizal symbiosis evolved ~400 million years ago when plants first moved onto land and formed an intimate association with fungi belonging to the phylum Glomeromycota. The symbiosis is characterized by an exchange of photosynthetically derived carbon from the plant for soil resources such as nitrogen (N) and phosphorus (P) provided by the fungus. Currently, two conceptual models of mycorrhizal functioning have been proposed. First, the functional equilibrium model predicts that positive and negative plant growth responses to AM fungi are largely determined by nitrogen or pho
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Mohanarajah, Thushanthan. "Analysis, design optimisation and experimental performance of synchronous reluctance and permanent magnet assisted synchronous reluctance machines." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56902.

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The research studies, in detail, the synchronous reluctance machine (SynRM) and permanent magnet assisted synchronous reluctance machine (PMSynRM) to improve the machine performances. In this study, the SynRM analytical models are revisited, and functional characteristics are mathematically developed to improve the machine performance. The performance parameters such as torque density, power factor, and efficiency are investigated along with torque ripples. SynRM is known for its high torque density in a compact size. Its improvement is analytically studied further by optimising rotor properti
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Dobrowohl, Felix. "Timbral transformation in contemporary music : event generation, perception thresholds and mixing preferences." Thesis, 2019. http://hdl.handle.net/1959.7/uws:56886.

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I approach timbre here primarily from the perspective of the music creator/producer, and the processes and considerations they apply in order to make recordings. Over the course of this thesis, I build a new synthesiser, whose sound manipulations (FX) are modelled after what would be typically used in a compositional or audio mixing context. These FX are, themselves, treated as the timbre descriptors. In the first experiment I try to establish units for these FX as measured in steps of smallest perceivable change of said parameter; the perception threshold (PT). This unit makes timbral changes
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O'Brien, Andrew N. "The ATLAS-SPT radio survey of cluster galaxies." Thesis, 2019. http://hdl.handle.net/1959.7/uws:51642.

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Galaxy clusters are the largest gravitationally bound objects in the Universe. The study of galaxy clusters can give insights into the large-scale structure of the Universe and provide constraints on the cosmological parameters that dictate the evolution of the Universe. Bent-tail radio sources are a class of Active Galactic Nuclei (AGN) where the jets or lobes have been distorted significantly due to the relative movement through a dense medium. This behaviour is expected to occur in galaxy clusters, especially those of high mass. I have planned and carried out the observations for the ATLAS-
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Tsai, Tuan-I. "Children who are overweight or obese : attitudes, beliefs and knowledge of nursing students in Taiwan." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54375.

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Background: Childhood overweight/obesity is a major public health problem in contemporary society. Controlling the childhood overweight/obesity epidemic requires an international effort. Nurses have a significant role to promote healthy lifestyle behaviours to prevent childhood overweight/obesity. Nurses’ attitudes and knowledge can influence the care of patients. There are only a few studies that address nurses’ attitudes, beliefs and knowledge about children who are overweight/obese. Understanding the attitudes, beliefs and knowledge of future nurses about childhood overweight/obesity can he
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Todd, Christopher M. "The ecology and conservation of the Christmas Island flying-fox (Pteropus natalis)." Thesis, 2019. http://hdl.handle.net/1959.7/uws:57389.

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On oceanic islands, where plants have coevolved with depauperate pollinator and seeddispersing guilds, flying-foxes (genus Pteropus) provide pollination and seed dispersal services that are vital for the maintenance of biodiversity. The high mobility of Pteropus species enable them to disperse seed and pollen across various island habitats, including disturbed areas where they are essential for the regeneration of forested habitats. However, despite their recognised importance, Pteropus species continue to decline across their range. More than 60% of Pteropus species are listed as Critically E
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Ghimire, Pramesh R. "Modelling perinatal and child mortality in Nepal." Thesis, 2019. http://hdl.handle.net/1959.7/uws:52996.

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South Asia has the second largest burden of perinatal and childhood mortality in the world and Nepal has been reported as a significant contributor to this burden within the region. The main aim of this thesis was to statistically model perinatal and childhood mortality in Nepal. Specifically, this thesis will first conduct a systematic review of factors associated with perinatal mortality in South Asia including Nepal. Second, socioeconomic predictors of stillbirths in Nepal will be examined. Third, Factors associated with perinatal mortality in Nepal will be identified. Finally, this t
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Farrell, Kaye. "Transition from paediatric to adult healthcare : effectiveness of the Westmead Diabetes Transition Service : (the TALENT study)." Thesis, 2019. http://hdl.handle.net/1959.7/uws:58347.

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The number of young adults diagnosed with type 1 diabetes is increasing globally and is the most common childhood non-communicable disease after asthma. Type 1 diabetes is a complex condition which requires 24- hour vigilance of blood glucose levels, insulin administration, and food and exercise. Individuals need to be well informed in self-management skills to prevent or respond to acute diabetes crises. In Australia, transition from paediatric to adult health care occurs at the end of schooling or between 16-18 years of age. Given the large numbers in paediatric care, young adults with type
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Hutcheson, Tiffany J. "Investment in property by Australian superannuation schemes." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53101.

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The superannuation sector in Australia accounts for close to AUD 2.5 trillion, representing major institutional investors in both a local and global context, of assets under management (AUM) in Australia's managed fund industry. This level of AUM makes up the majority of AUM in the industry. Over the past few decades, superannuation schemes have come to regard property as a key asset class to include in their multi-asset portfolios. This thesis explores the decision-making made by superannuation schemes when investing in property. lt does this by identifying the main criteria used in this deci
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Zeng, Xiamiao. "An analysis of mathematical processes and understanding in a tutoring intervention : the case of trigonometry." Thesis, 2019. http://hdl.handle.net/1959.7/uws:61937.

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Trigonometry is a topic that teachers often find hard to teach, and students can find it difficult and confusing. The topic of trigonometry is a topic that links algebraic concepts, number skills and geometric meanings together, and many students are not accustomed to this integrated way of learning different mathematical strands. Relational understanding, as defined by Skemp, has received a lot of attention from researchers and teachers, but it is very difficult for students to achieve relational understanding, especially in trigonometry. In addition, there is a scarcity of methods and approa
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Hodgins, Michael. "Emotions and mindlines : a palliative care perspective." Thesis, 2019. http://hdl.handle.net/1959.7/uws:63466.

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This thesis explores the relationship between emotion and mindlines in palliative care. This contributes to the processual turn in organisational studies by using Deleuze and Guattari’s (1987) notion of the assemblage to illuminate the processual nature of knowledge translation in palliative care. The processual perspective of organisational theory clarifies the mutual shaping between the ‘material’ and the ‘social’ when considering how emotion affects knowledge and practice. An emerging paradigm of evidence-based practice privileges the socially-constituted nature of knowledge, predicated on
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Power, Tamara. "Disrupted mothering : a drama in four acts." Thesis, 2012. http://handle.uws.edu.au:8081/1959.7/564866.

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The majority of women in the world will experience motherhood, and for most of them it is a profound and life-changing undertaking. In Western society contemporary motherhood is beset by social constructions of ‘good’ mothering. The social construct of the ‘good’ mother has consequences for how women enact and experience mothering, often culminating in feelings of intense responsibility, guilt and shame. These feelings are magnified when women are disrupted in their mothering by illness. Although some literature has explored mothering in the context of specific illnesses, the concept of disrup
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Levett, Kate M. "The complete birth study : effectiveness of a complex antenatal education program incorporating complementary medicine techniques for pain relief in labour and birth for first-time mothers : a mixed methods study [The complementary therapies for labour and birth study : effectiveness of a complex antenatal education program incorporating complementary medicine techniques for pain relief in labour and birth for first-time mothers : a mixed methods study]." Thesis, 2015. http://hdl.handle.net/1959.7/uws:34104.

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Background: Reviews of maternity services in Australia have called for a reduction in interventions and an increase in education and support to increase rates of normal birth. Evidence suggests that selected complementary therapies (CM) are effective during labour to assist with the management of pain, and in decreasing interventions. Antenatal education, in the Australian maternity context, has shifted from its original focus of birth preparation, to a broader focus on overall pregnancy, birth and parenting information. The aim of this study was to evaluate the effectiveness of a complementar
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Radzieta, Michael. "The novel anti-infective BDM-I : clinical utility and mechanism of action." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54518.

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Since the introduction of antibiotics into clinical use, bacteria have continued to evolve and acquire mechanisms of resistance. In a relatively short time period, this has rapidly escalated into a serious health crisis recognised by major governing/scientific bodies worldwide. The rate at which antibiotic resistance spreads now outpaces our current ability to discover and manufacture new antibiotics. Steps taken to combat antibiotic resistance have had little impact in preventing the spread of relevant pathogens, especially within hospital settings. The current state of antibiotic development
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Ullah, Faheem. "The effects of two highly bioavailable curcumin preparations on the activation of glial cells and chronic neuroinflammation in GFAP-IL6 mice." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54514.

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Neuroinflammation is a pathophysiological process present in a number of neurodegenerative disorders, including following acute insults such as stroke, traumatic brain injury including chronic traumatic encephalopathy as well as age-related CNS disorders such as Huntington’s disease, Parkinson’s disease and Alzheimer’s disease (AD). Although there is still much debate over the initial trigger for these neurodegenerative disorders, neuroinflammation appears to be a major contributor, and therefore anti-inflammatory drugs including cytokine suppressive anti-inflammatory drugs (CSAIDs) might be p
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Eftekharian, Esmaeel. "Investigation of buoyant plume wind enhancement." Thesis, 2019. http://hdl.handle.net/1959.7/uws:58465.

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Bushfires are a natural disaster that has a devasting effect on nature and mankind. The vulnerability of buildings to bushfires has caused enormous loss of property and in extreme conditions, loss of life. It is well known that bushfires invade building structures via three mechanisms, namely embers, thermal radiation, and flame contact. Based on recent bushfire field surveys and numerical simulations, bushfire enhanced wind has also been identified to be a major contributor to building damage. Wind enhancement by bushfires can have a destructive impact on buildings arising from the increasing
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Williams, Joseph. "Rhizomatic thinking and traditional music as difference-in-itself : a virtual historical revision of England's Victorian/Edwardian folk revival." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54511.

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This dissertation problematizes the principle of identity in the contemporary understanding and evaluation of traditional music in international contexts. Through a virtual historical revision of England’s folk revival of the late nineteenth and early twentieth centuries, I ask whether it is possible to rethink the concept of traditional music in terms of what Gilles Deleuze called difference-in-itself. The orientation of my historical revision is informed by Deleuze’s concept of the virtual, which concerns the relationship between the past, as it exists in the present without being actual, an
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Pourmohammadimojaveri, Samaneh. "High performance rubber concrete." Thesis, 2019. http://hdl.handle.net/1959.7/uws:55713.

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The fast development of the automotive industry after the Second World War led to the rapid accumulation of waste tyre rubber. Since 1963, finding applications for the use of waste tyres has become the center of attention for many researchers. Using waste tyres in concrete has been proposed by many researchers, but due to its flexibility combined with hydrophobicity, any structural applications of such concrete has been difficult to develop. The mechanical properties of concrete, such as its compressive strength, modulus of rupture and tensile strength, are adversely affected by the addition o
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Bellot-Saez, Alba. "Astrocytic modulation of neuronal network oscillations." Thesis, 2019. http://hdl.handle.net/1959.7/uws:54319.

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The synchronization of the neuron’s membrane potential results in the emergence of neuronal oscillations at multiple frequencies that serve distinct physiological functions (e.g. facilitation of synaptic plasticity) and correlate with different behavioural states (e.g. sleep, wakefulness, attention). It has been postulated that at least ten distinct mechanisms are required to cover the large frequency range of neuronal oscillations in the cortex, including variations in the concentration of extracellular neurotransmitters and ions, as well as changes in cellular excitability. However, the mech
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Chong, Cheeseng. "Investigating spoken emotion : the interplay of language and facial expression." Thesis, 2019. http://hdl.handle.net/1959.7/uws:53922.

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This thesis aims to investigate how spoken expressions of emotions are influenced by the characteristics of spoken language and the facial emotion expression. The first three chapters examined how production and perception of emotions differed between Cantonese (tone language) and English (non-tone language). The rationale for this contrast was that the acoustic property of Fundamental Frequency (F0) may be used differently in the production and perception of spoken expressions in tone languages as F0 may be preserved as a linguistic resource for the production of lexical tones. To test this i
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Collison, Anneke J. "The navigation of post-transition identity and disclosure by gender diverse Australian adults." Thesis, 2019. http://hdl.handle.net/1959.7/uws:51911.

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Based on qualitative research, this PhD investigated the navigation of post-transition disclosure in a sample of Australians who are gender diverse. 100 participants completed an online survey focusing on disclosure through their lifetime in different social contexts. Semi-structured interviews were then held with 25 participants who varied in age, gender, and sexuality, to develop a more detailed understanding of these varied disclosure experiences. Twelve participants identified as men and/or used male pronouns, and eleven identified as women and/or used female pronouns. One participant iden
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Nair, Girish. "Development of a real-time business intelligence (BI) framework based on hex-elementization of data points for accurate business decision-making." Thesis, 2019. http://hdl.handle.net/1959.7/uws:55127.

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The desire to use business intelligence (BI) to enhance efficiency and effectiveness of business decisions is neither new nor revolutionary. The promise of BI is to provide the ability to capture interrelationship from data and information to guide action towards a business goal. Although BI has been around since the 1960s, businesses still cannot get competitive information in the form they want, when they want and how they want. Business decisions are already full of challenges. The challenges in business decision-making include the use of a vast amount of data, adopting new technologies, an
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Ramdhan, Dadang. "Foreign direct investment in Indonesia." Thesis, 2019. http://hdl.handle.net/1959.7/uws:55128.

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This study addresses the needs of Indonesian policymakers, to not only investigate the determinant factors of FDI inflow in manufacturing sector across Indonesian provinces, but to also investigate the impact of FDI spillover on firm’s total factor productivity growth (TFPG) through product and labour markets and the role of provincial human capital on FDI-TFPG nexus. This study addresses the questions; 1) what is the impact of FDI spillover on the TFPG of Indonesian manufacturing firms in product and labour markets across sectors and within a province by considering different kinds of
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Hassanli, Sina. "Flow enhancement in and around buildings for wind energy harvesting." Thesis, 2019. http://hdl.handle.net/1959.7/uws:52381.

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Decentralised small-scale wind energy harvesting in urban environments, as one of the potential solutions to tackle the energy crisis and climate change, requires the development of flow enhancement techniques in a fairly turbulent urban wind condition. This study proposes two types of building and façade configurations, including adaptive Double Skin Façade (DSF) and aerodynamic through-building openings, to enhance wind energy harvesting in and around buildings. Depending on their layout configuration, the two proposals form various types of confined aerodynamic duct-shape corridors suitable
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Ying, Jia. "Evidence for active control of tongue lateralisation in Australian English /l/ and its acoustic consequences." Thesis, 2019. http://hdl.handle.net/1959.7/uws:55248.

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This thesis provided new insights into lateral production by addressing the following questions: (1) what are the primary production goals of /l/; and (2) how do the articulatory goals of /l/ production relate to their acoustic properties? To investigate the production goals of /l/ and the articulatory-acoustic relation, a three-dimensional (3D) electromagnetic articulography (EMA) study was conducted with simultaneous acoustic recording. Six speakers were recorded. Sensors were located at key points on the midline and sides of the tongue to track lateralisation. The analyses made use of both
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