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1

McCandless, David W. Thiamine deficiency and associated clinical disorders. Humana Press, 2010.

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2

McCandless, David W. Thiamine Deficiency and Associated Clinical Disorders. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-311-4.

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3

Carpenter, Kenneth J. Beriberi, white rice, and vitamin B: A disease, a cause, and a cure. University of California Press, 2000.

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4

Carpenter, Kenneth J. Beriberi, white rice, and vitamin B: A disease, a cause, and a cure. University of California Press, 2000.

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5

McCandless, David W. Thiamine Deficiency and Associated Clinical Disorders. Humana Press, 2012.

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6

Marrs, Chandler, and Derrick Lonsdale. Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition. Elsevier Science & Technology Books, 2017.

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Marrs, Chandler, and Derrick Lonsdale. Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition. Elsevier Science & Technology Books, 2017.

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8

Gluckman, Sir Peter, Mark Hanson, Chong Yap Seng, and Anne Bardsley. Vitamin B1 (thiamine) in pregnancy and breastfeeding. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198722700.003.0007.

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Vitamin B1 (thiamine) is involved in nervous system and muscle function and is essential for carbohydrate metabolism. Deficiency is common in Asia, where diets are often high in thiamine-depleted polished rice and can be low in other food sources. Pregnancy imposes an increasing requirement for thiamine over the course of gestation, and deficiency can lead to widespread metabolic disturbances affecting the placenta and fetus. Nutritional deficiency for thiamine is rare in people who consume a moderately varied diet that contains whole grains. However, excessive vomiting in pregnancy can cause
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9

Janssen, Mirian C. H., and Shamima Rahman. Pyruvate Dehydrogenase Complex Deficiency. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0006.

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Pyruvate dehydrogenase complex (PDHc) deficiency usually first manifests at a young age and is rarely diagnosed in adulthood. The clinical picture varies from neonatal death with overwhelming lactic acidosis to a relatively benign course early in life. The three main presentations are congenital lactic acidosis, Leigh syndrome, and episodic ataxia. Treatment consists of a ketogenic diet and cofactor supplementation with thiamine. Successful therapy is rare.
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10

Bâ, Abdoulaye. Maternal Alcohol Intake, Thiamine (vitamine B1) Deficiency and Central Nervous System Development. BAYSHOP (Generis Publishing), 2023.

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11

Cohen, Jeffrey A., Justin J. Mowchun, Victoria H. Lawson, and Nathaniel M. Robbins. A 40-Year-Old Female with Balance Problems and Numbness After Bariatric Surgery. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190491901.003.0011.

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A number of nutritional causes of peripheral neuropathy have been identified. Patients who have gastrointestinal disease or who have undergone bariatric surgery are at risk, although frequently the specific cause is not ascertained. Vitamin B12 and thiamine deficiencies are the most common causes in bariatric surgery patients. The classic clinical picture of Vitamin B12 deficiency is a myelopathy with a concomitant peripheral neuropathy. Thiamine deficiency is the classic triad of mental status changes, opthalmoplegia, and ataxia. Copper deficiency is often unrecognized. Its presentation can b
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12

Zenuk, Cecli. Prevalence of thiamine deficiency in congestive heart failure patients receiving long-term furosemide therapy. 2000.

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13

Ramrakha, Punit, and Jonathan Hill, eds. Cardiovascular disease in less-developed countries. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199643219.003.0014.

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Burden of cardiovascular disease in less-developed countries 654Infectious disease and the heart 656Diphtheria 657HIV and the cardiovascular system 658Chagas’ disease and the heart 660Cardiovascular syphilis 662Beri-beri (thiamine deficiency) 664Tetanus 666Keshan disease 667Restrictive cardiomyopathy 667Endomyocardial fibrosis ...
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14

Carpenter, Kenneth J. Beriberi, White Rice and Vitamin B: A Disease, a Cause, and a Cure. Diane Pub Co, 2000.

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15

Beriberi, white rice, and vitamin B: A disease, a cause, and a cure. University of California Press, 2000.

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16

Silva, Aminda De, J. A. Saunders, and M. A. Stroud. Vitamin deficiencies. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0333.

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Vitamins are organic compounds required by the body in small amounts to perform specific cellular functions. Nine vitamins (thiamine (vitamin B1), riboflavin (vitamin B2), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12), niacin (nicotinic acid; vitamin B3), pantothenic acid (vitamin B5), biotin (vitamin B7; vitamin H), folic acid (folate; vitamin B9), and ascorbic acid (vitamin C)) are water soluble, while four (vitamins A, D, E, and K) are fat soluble. The importance of vitamins was first appreciated through recognition of their clinical deficiency state. However, this approach has led
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17

Bay, Alexander R. Beriberi in Modern Japan: The Making of a National Disease. University of Rochester Press, 2012.

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18

Beriberi in Modern Japan: The Making of a National Disease. University of Rochester Press, 2012.

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19

Shangari, Nandita. Interdependent toxicity mechanisms of oxidative stress, thiamin deficiency and alpha-oxoaldehydes. 2006.

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20

Hanninen, Stacy Ann. The prevalence of thiamin deficiency in hospitalized patients with congestive heart failure. 2004.

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