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Relevant bibliographies by topics / Thiazole compounds

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Academic literature on the topic 'Thiazole compounds'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Thiazole compounds"

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Hosseini, Akram Karbalaee, and Azadeh Tadjarodi. "Luminescent MOFs Based on Thiazolo[5,4-d]thiazole as a Chemosensor for the Detection of Environmental Contaminants." Journal of Nanotechnology and Nanomaterials 5, no. 1 (2024): 1–6. http://dx.doi.org/10.33696/nanotechnol.5.047.

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Luminescent metal-organic frameworks (LMOFs) are considered special candidates for the sensation and detection of particular analytes. Thiazolo[5,4-d]thiazoles (TTZs) are an ideal type of heterocycles for fluorophores with π-bridge moieties demonstrating structure-function characteristics. LMOFs with excellent sensing properties can be constructed by incorporating heterocyclic aromatic thiazolo[5,4-d]thiazole into the framework. This study has elaborated on LMOFs containing thiazolo[5,4-d]thiazole unit for the detection of environmental contaminants, such as toxic anions, aromatic compounds, a

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Rayala, Ramanjaneyulu, Prakash Chaudhari, Ashley Bunnell, Bracken Roberts, Debopam Chakrabarti, and Adel Nefzi. "Parallel Synthesis of Piperazine Tethered Thiazole Compounds with Antiplasmodial Activity." International Journal of Molecular Sciences 24, no. 24 (2023): 17414. http://dx.doi.org/10.3390/ijms242417414.

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Thiazole and piperazine are two important heterocyclic rings that play a prominent role in nature and have a broad range of applications in agricultural and medicinal chemistry. Herein, we report the parallel synthesis of a library of diverse piperazine-tethered thiazole compounds. The reaction of piperazine with newly generated 4-chloromethyl-2-amino thiazoles led to the desired piperazine thiazole compounds with high purities and good overall yields. Using a variety of commercially available carboxylic acids, the parallel synthesis of a variety of disubstituted 4-(piperazin-1-ylmethyl)thiazo

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Borde, Ramesh M., Satish B Jadhav, Rahul R Dhavse, and Achut S Munde. "DESIGN, SYNTHESIS, AND PHARMACOLOGICAL EVALUATION OF SOME NOVEL BIS-THIAZOLE DERIVATIVES." Asian Journal of Pharmaceutical and Clinical Research 11, no. 4 (2018): 164. http://dx.doi.org/10.22159/ajpcr.2018.v11i4.23413.

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Objective: A series of substituted 5,2-bis-thiazoles derivatives were synthesized by Hantzsch reaction and evaluated in vitro for antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus. Methods: 2-(4-(benzyloxy)phenyl)-4-methylthiazole-5-carbothioamide were synthesized and allowed to react with various α-haloketones to give 5,2-bis-thiazoles, i.e., 2-(4-(benzyloxy)phenyl)-4-methyl-5-(4-substituted thiazol-2-yl)thiazole derivatives in excellent yield. The synthesized compounds were characterized by spectroscopic methods as well as e

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Abu-Melha, Sraa. "Synthesis, Modeling Study and Antioxidants Activity of New Heterocycles Derived from 4-Antipyrinyl-2-Chloroacetamidothiazoles." Applied Sciences 8, no. 11 (2018): 2128. http://dx.doi.org/10.3390/app8112128.

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The present work reports the preparation of twelve new heterocyclic scaffolds containing an antipyrinyl-thiazole hybrid through the reaction of 4-antipyrinyl-2-chloroacetamido-thiazoles 1 and 6 with various types of nucleophiles, namely; ethyl thioglycolate, 2-mercaptobenzothiazole, 2-mercaptobenzoxazole, ammonium thiocyanate, malononitrile, and salicylaldehyde. The constructed compounds were characterized by conventional spectroscopic techniques (IR, 1H NMR, 13C NMR, and mass analysis). A DFT method (material studio package) was used to predict the geometry, bond lengths, bond angles, and dip

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Singh, Inder P., Shiv Gupta, and Sanjay Kumar. "Thiazole Compounds as Antiviral Agents: An Update." Medicinal Chemistry 16, no. 1 (2020): 4–23. http://dx.doi.org/10.2174/1573406415666190614101253.

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Background: Thiazole is a good nucleus owing to its various pharmaceutical applications. Thiazole containing compounds (thiazoles) have shown various biological activities like antioxidant, analgesic, antibacterial, anticancer, antiallergic, antihypertensive, antiinflammatory, antimalarial, antifungal and antipsychotic. The scaffold is present in more than 18 FDA approved drugs and also in more than 70 experimental drugs. Only a few reviews are available in the literature despite its great medicinal importance. During the course of time, this scaffold has been studied extensively for its antiv

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Dekate, Shital M., Kishor M. Hatzade, and Ajay M. Ghatole. "A Facile Synthesis of Thiazole Derivatives bearing Imidazole Moiety, Schiff Bases and their O-Glucosides." Asian Journal of Chemistry 35, no. 1 (2022): 29–38. http://dx.doi.org/10.14233/ajchem.2023.24049.

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A unique approach for the synthesis of new thiazole O-glycosides is presented in this work. 2-Amino-4-hydroxy-phenyl-1,3-thiazole-5-carboxaldehyde (3a) was reacted with phenyl glyoxal and benzil to form 4-(4-hydroxy-phenyl)-5-(4-phenyl-1H-imidazol-2-yl)-thiazol-2-amine (4a) and 4-(4-hydroxy-phenyl)-5-(4,5-diphenyl-1H-imidazol-2-yl)-thiazol-2-amine (4b), respectively. A series of substituted Schiff bases of 4a and 4b were synthesized reacting with various aryl aldehyde to form 2-(imino substituted benzal)-4-(4-hydroxy-phenyl)-5-(4-phenyl-1H-imidazol-2-yl)-thiazoles (5a-e) and 2-(imino substitut

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Slyvka, N. Yu, L. M. Saliyeva, V. I. Zhylko, V. M. Tkachuk, and M. V. Vovk. "Synthesis and antioxidant activity of new 2-(2-oxoindoline-3-ylydene) substituted 5,6-dihydroimidazo[2,1-b]thiazolones and 6,7-dihydro-thiazolo[3,2-a]pyrimidinones." Voprosy Khimii i Khimicheskoi Tekhnologii, no. 1 (February 2025): 71–79. https://doi.org/10.32434/0321-4095-2025-158-1-71-79.

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The paper presents the results of the study on the interaction of 5,6-dihydroimidazo[2,1-b]thiazoles and 6,7-dihydrothiazolo[3,2-a]pyrimidines with isatin derivatives. It was established that the condensation of the indicated reagents occurs selectively upon heating and without the use of a catalyst with the formation of addition products, 2-(2-oxoindolin-3-ylidene)-5,6-dihydroimidazo[2,1-b]thiazole-3(2H)-ones 6a–d and 2-(2-oxoindolin-3-ylidene)-6,7-dihydro-2H-thiazolo[3,2-a]pyrimidin-3(5H)-ones 7a–c, the structure of which was rigorously proven by 1H NMR (13C) spectroscopy and chromatography-

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Erguc, Ali, Mehlika Dilek Altintop, Ozlem Atli, et al. "Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents." Letters in Drug Design & Discovery 15, no. 2 (2018): 193–202. http://dx.doi.org/10.2174/1570180814666171003145227.

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Background: In medicinal chemistry, thiazoles have gained great importance in antifungal and anticancer drug design and development. Objectives: The aim of this study was to synthesize new quinoline-based thiazolyl hydrazone derivatives and evaluate their anticandidal and anticancer effects. Methods: New thiazolyl hydrazone derivatives were evaluated for their anticandidal effects using disc diffusion method. Ames MPF assay was carried out to determine the genotoxicity of the most effective antifungal derivative. MTT assay was also performed to assess the cytotoxic effects of the compounds on

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Mishchenko, Mariia, Sergiy Shtrygol, Danylo Kaminskyy, and Roman Lesyk. "Thiazole-Bearing 4-Thiazolidinones as New Anticonvulsant Agents." Scientia Pharmaceutica 88, no. 1 (2020): 16. http://dx.doi.org/10.3390/scipharm88010016.

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Here, we describe the synthesis and anticonvulsant activity of thiazole-bearing hybrids based on 2-imino-4-thiazolidinone and 2,4-dioxothiazolidine-5-carboxylic acid cores. The structure of target compounds was based on the following: (i) A combination of two thiazole cores; (ii) similarity to ralitolin’s structure; (iii) the compliance with structural requirements for the new anticonvulsants. Target compounds were synthesized via known approaches based on Knoenavegel reaction, alkylation reaction, and one-pot three-component reaction. Anticonvulsant properties of compounds were evaluated in t

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Ram, Sevak Verma*1 Nitin Mittal2 Bhumika Yogi3 Shikha Sharma4 Abhishek Mishra5. "A Review On Chemistry And Antimicrobial Activity Of Thiazole." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 1184–201. https://doi.org/10.5281/zenodo.10893122.

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The recent study classe of five-membered heterocyclic compounds is thiazoles. Several thiazoles, both synthetic and natural, and their derivatives exhibited strong biological activity. Thiazole derivatives exhibit strong antibacterial action against a variety of bacterial species & diseases because of their special characteristics. As a result, the current study assigns different thiazoles and there derivatives' antimicrobial activity. Through the use of many databases, every pertinent piece of literature has been examined. The important studies on the antibacterial activity of thiazole de

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Dissertations / Theses on the topic "Thiazole compounds"

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Olawode, Emmanual Oladayo. "Synthesis and biological evaluation of novel thiazole-based compounds." Thesis, Rhodes University, 2016. http://hdl.handle.net/10962/62955.

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Baker, Luke Anthony. "Nucleohilic heteroaromatic thiazole substitution and towards the total synthesis of azedaralide, odoratin and mexicanolide /." [St. Lucia, Qld.], 2006. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe20242.pdf.

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梁曼儀 and Man-yee Leung. "Synthetic investigations into [delta]4-1, 2-thiazoline 1, 1-dioxides." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1985. http://hub.hku.hk/bib/B31207340.

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Leung, Man-yee. "Synthetic investigations into [delta]4-1, 2-thiazoline 1, 1-dioxides /." [Hong Kong : University of Hong Kong], 1985. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12348739.

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Van, der Merwe Madelein. "Nuwe groep 6 metaalkarbonielkomplekse met tiofeenligande en Au(I)komplekse met tiasole." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/49774.

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Boukraa, Sadok. "Préparation, réactivité et étude des propriétés fongistatiques et immunostimulantes d'amino-2 thiazoles et d'imidazo-(2,1-B) thiazoles." Besançon, 1987. http://www.theses.fr/1987BESA2030.

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Le travail se divise en deux grandes parties : la premiere concerne la preparation d'aryl-6 imidazo(2,1-b) thiazoles substitues en 3 par des chaines de type acetate d'ethyle, aroylmethyle. (beta -hydroxy beta -aryl)ethyle te arylethyle. Pour ce faire, il a ete necessaire de preparer les amino-2 thiazoles corespondants substitues par ces memes chaines en 4 afin de las opposer a des acetophenones omega -bromees. L'influence des substituants presents est discutee en vue d'aprehender l'evolution des reactions. La seconde partie concerne des essais en tant que fongistatiques et/ou immunostimulants

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Laduranty, Joëlle. "Mise au point de la préparation de molécules polyfonctionnelles comportant l'unité structurale SCCN de la cystéamine : applications en radioprotection et synthèse organique." Poitiers, 1988. http://www.theses.fr/1988POIT2013.

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Almeida, Mário Rui Dias. "Synthesis of 5-aryl-imidazo [2,1-b] thiazole compounds possibly RAF kinase inhibitors." Master's thesis, 2014. http://hdl.handle.net/10451/38753.

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Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2014<br>Malignant melanoma is the most aggressive type of skin cancer because of its high tendency to metastasize. In fact, the mortality rate from malignant melanoma has risen about 2% annually since 1960. Malignant melanoma occupies the 19th place as the most common cancer worldwide. In Portugal, according to the Portuguese League Against Cancer are nearly 700 new cases of melanoma annually and the incidence rate reaches 6-8 cases per 100000 individuals. These data are similar to Sou

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Marais, Eugene Krige. "Tiasoolderivate as ligande vir karbonielkomplekse van die groep 6 metale en yster." Thesis, 2012. http://hdl.handle.net/10210/6507.

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M.Sc.<br>This study comprised the synthesis and characterization of new carbonyl carbene complexes of chromium, molybdenum and tungsten, prepared from thiazole precursors. In addition, the preparation and characterization of coordination compounds of chromium, tungsten and iron with new thiazole dithiocarboxylester ligands are reported.

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Hu, Tzu-Li, and 胡自立. "The Synthesis of Poly(Pyridine-thiazole)Stationary-Phase and it Application in the fullerenences and other compound by HPLC." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/14660938462778648185.

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碩士<br>中正理工學院<br>應用化學學系研究所<br>86<br>Abstract A novel stationary phase was synthesized in this study. In the synthesis, a coupling agent, γ-methacryloxypropyltrimetoxy silane, was adopted. The stationary phase (VP-mv-CA-phase) was prepared by chemically bonding the coupling agent with silica gel at one end and subsequently polymerized with the compounds of pyridine and thiazole derivative at the other end. Abstract Abstract A novel stationary phase was synthesized in this study. In the synthesis, a

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Books on the topic "Thiazole compounds"

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Sowoidnich, Werner. Neue Chelate der Benzthiazol- und Benzobisthiazolreihe: Darstellung und spektroskopische Eigenschaften. Hartung-Gorre, 1989.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 3. Wiley & Sons, Incorporated, John, 2008.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 1. Wiley & Sons, Incorporated, John, 2009.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 1. Wiley & Sons, Incorporated, John, 2008.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 2. Wiley & Sons, Incorporated, John, 2009.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 2. Wiley & Sons, Limited, John, 2007.

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Thiazole and Its Derivatives, Part 3. Wiley & Sons, Incorporated, John, 2009.

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Bambas, L. L. Chemistry of Heterocyclic Compounds, Five Member Heterocyclic Compounds with Nitrogen and Sulfur or Nitrogen, Sulfur and Oxygen Except Thiazole. Wiley & Sons, Incorporated, John, 2008.

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Bambas, L. L. Five Member Heterocyclic Compounds with Nitrogen and Sulfur or Nitrogen, Sulfur and Oxygen (Except Thiazole). Wiley & Sons, Incorporated, John, 2009.

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Book chapters on the topic "Thiazole compounds"

1

Metzger, Jacques V., Emile-Jean Vincent, Jacques Chouteau, and Gilbert Mille. "Properties and Reactions of Thiazole." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187081.ch2.

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Aune, Jean Pierre, Henri Jean-Marie Dou, and Jacqueline Crousier. "Alkyl, Aryl, Aralkyl, and Related Thiazole Derivatives." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187081.ch4.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of manganese(II) complex with 2-mercaptobenzo-thiazole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54228-6_389.

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Vernin, Gaston. "General Synthetic Methods for Thiazole and Thiazolium Salts." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187081.ch3.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with thiazole Schiff-base." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 3. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62470-8_171.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) with 2-(pyrazin-2-ylamino)-4-(pyridin-2-yl)thiazole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_28.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with nitronyl nitroxide substituted thiazole." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 3. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62470-8_51.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 2-(pyrazin-2-ylamino)-4-(pyridine-2-yl)thiazole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_29.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 2-(pyrazin-2-ylamino)-4-(pyridin-2-yl)thiazole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_30.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 2-(pyrazin-2-ylamino)-4-(pyridin-2-yl)thiazole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_31.

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Conference papers on the topic "Thiazole compounds"

1

Putri, Chantika Octaviani, and Antonius Herry Cahyana. "Synthesis and antioxidant activity screening of thiazole and oxazole derivative compounds." In INTERNATIONAL CONFERENCE ON SCIENCE AND APPLIED SCIENCE (ICSAS) 2021. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0072502.

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Radovanović, Marko, Ignjat Filipović, Maja Đukić, Marija Ristić, Ivan Jakovljević, and Zoran D. Matović. "Molecular docking study of ruthenium-p-cymene complexes with isothiazole derivatives as SARS-CoV-2 main protease inhibitors." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.387r.

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Since proper treatment for COVID-19 still has not been developed, exploration of novel options is required. Activities of different metal complexes, promising results gained from examining different thiazole derivatives, and research in the field of natural products like p-cymene, produced an idea to test piano stool ruthenium p-cymene complexes with isothiazole derivatives as ligands. In silico methods are often used as the first step in a series of experiments during the development of new drugs, and docking simulations are a quick way to determine the feasibility of novel compounds as poten

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Ustinov, Ilya, Nikolaj Khlytin, Yurij Atroshchenko, and Irina Shahkeldyan. "NEW THIAZOL DERIVATIVES CONTAINING NITRO QUINOLINE FRAGMENT." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m797.aks-2019/383-384.

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Radulescu, Victorita. "New Solution With Syntheses Inhibitors for the Chemical Cleaning of Organic Pollutants From the Water Supply System Of Generators." In ASME 2021 Power Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/power2021-64314.

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Abstract In thermal power plants, during the boilers functioning, heterogeneous deposits of substances must often be removed in order to prolong their operation and avoid their deterioration. The nature, type and quantity of deposits depend on the characteristics of the water supply systems and the chemical operating regime. For boilers with high deposits of copper and iron, the utilization of mineral acids for chemical cleaning is not quite effective, because their surfaces may be covered with a metal copper film. Organic impurities in the water supply affect the operation of steam generators

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VELAZCO MONTAGNA, Federico Juan, Gloria Patricia CAMARGO SOLORZANO, María Isabel SOARES, Teresa María V. D. PINHO E MELO, and Walter José PELÁEZ. "FLASH VACUUM PYROLYSIS (FVP) OF DIMETHYL 5-METHYL-3-PHENYL-1H,3H-PYRROLO[1,2-C]THIAZOLE-6,7-DICARBOXYLATE 2,2-DIOXIDE: KINETIC AND THERMAL PARAMETERS." In Second Southern Science Conference - 2024. Araucária - Associação Científica, 2024. https://doi.org/10.48141/sscon_51_2024.pdf.

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The generation through FVP and reactivity of an azafulvenium derived from thermal SO2 extrusion of dimethyl 5-methyl-3-phenyl-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2,2-dioxide (compound 1) is described. Synthesis of 1 is briefly shown (Scheme 1, Sutcliffe et al., 2001). The intermediate azafulvenium was previously shown to be trapped by dipolarophiles, acting either as a 4? or 8? dipole (Pinho e Melo et al., 2004). A pyrolysis mechanism is proposed (Scheme 2). Three products were found, two of which were not previously reported (Scheme 3, 2cis and 3). The characterization by NMR, UV-V

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Moses, Liji E., S. Pari, Isaac Hubert Joe, B. Kunhanna Sarojini, and Krishnakishore Majalakere. "Spectroscopic, DFT and Z-scan assisted study of an azo compound N-(2,6-dimethylphenyl)-4-(4-chlorophenyl) thiazol-2-amine." In 2ND INTERNATIONAL CONFERENCE ON MATERIALS FOR ENERGY AND ENVIRONMENT 2020. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0141624.

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Arnout, J., A. Van Hecken, I. Delepeleire, et al. "EFFECTIVENESS AND TOLERABILITY OF CV-3988, A SELECTIVE PAF ANTAGONIST, AFTER INTRAVENOUS ADMINISTRATION TO MAN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642878.

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Platelet activating factor (PAF) is a naturally occurring phospholipid with a wide spectrum of biological activities. Although PAF has been ascribed a potential role in various conditions including inflammation, asthma, glomerulonephritis and thrombosis, its precise function in physiologic/pathophysiologic processes remains unclear. The introduction of selective PAF receptor antagonists could represent a useful tool to extend our knowledge of the role of this mediator in health and disease.We have investigated the efficacy and tolerability of (RS)-2-methoxy-3-(octadecylcarbomoyloxy)propy1 2-(3

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