Academic literature on the topic 'Thiazoles'

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Journal articles on the topic "Thiazoles"

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Borde, Ramesh M., Satish B Jadhav, Rahul R Dhavse, and Achut S Munde. "DESIGN, SYNTHESIS, AND PHARMACOLOGICAL EVALUATION OF SOME NOVEL BIS-THIAZOLE DERIVATIVES." Asian Journal of Pharmaceutical and Clinical Research 11, no. 4 (2018): 164. http://dx.doi.org/10.22159/ajpcr.2018.v11i4.23413.

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Objective: A series of substituted 5,2-bis-thiazoles derivatives were synthesized by Hantzsch reaction and evaluated in vitro for antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus. Methods: 2-(4-(benzyloxy)phenyl)-4-methylthiazole-5-carbothioamide were synthesized and allowed to react with various α-haloketones to give 5,2-bis-thiazoles, i.e., 2-(4-(benzyloxy)phenyl)-4-methyl-5-(4-substituted thiazol-2-yl)thiazole derivatives in excellent yield. The synthesized compounds were characterized by spectroscopic methods as well as e
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Dekate, Shital M., Kishor M. Hatzade, and Ajay M. Ghatole. "A Facile Synthesis of Thiazole Derivatives bearing Imidazole Moiety, Schiff Bases and their O-Glucosides." Asian Journal of Chemistry 35, no. 1 (2022): 29–38. http://dx.doi.org/10.14233/ajchem.2023.24049.

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A unique approach for the synthesis of new thiazole O-glycosides is presented in this work. 2-Amino-4-hydroxy-phenyl-1,3-thiazole-5-carboxaldehyde (3a) was reacted with phenyl glyoxal and benzil to form 4-(4-hydroxy-phenyl)-5-(4-phenyl-1H-imidazol-2-yl)-thiazol-2-amine (4a) and 4-(4-hydroxy-phenyl)-5-(4,5-diphenyl-1H-imidazol-2-yl)-thiazol-2-amine (4b), respectively. A series of substituted Schiff bases of 4a and 4b were synthesized reacting with various aryl aldehyde to form 2-(imino substituted benzal)-4-(4-hydroxy-phenyl)-5-(4-phenyl-1H-imidazol-2-yl)-thiazoles (5a-e) and 2-(imino substitut
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Tokárová, Zita, and Anna Biathová. "Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles." Nova Biotechnologica et Chimica 17, no. 2 (2018): 193–200. http://dx.doi.org/10.2478/nbec-2018-0020.

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Abstract Substituted thiophene-2-carbaldehydes 1a-dwere utilized in the synthesis of symmetrically substituted thiazolo[5,4-d]thiazoles 3a-d. Bis(5,4-d)thiazoles with thiophene core at the termini are the most employed in the chemistry of materials but exhibit insufficient solubility in majority of organic solvents with notable impact on the low yields of products. Accordingly, the synthetic approach towards 2,5-dithiophen- 2-yl-thiazolo[5,4-d]thiazole (3a) and its substituted derivatives 3b-d is discussed under the various reaction conditions. Appropriate structural characterisations are incl
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Hosseini, Akram Karbalaee, and Azadeh Tadjarodi. "Luminescent MOFs Based on Thiazolo[5,4-d]thiazole as a Chemosensor for the Detection of Environmental Contaminants." Journal of Nanotechnology and Nanomaterials 5, no. 1 (2024): 1–6. http://dx.doi.org/10.33696/nanotechnol.5.047.

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Luminescent metal-organic frameworks (LMOFs) are considered special candidates for the sensation and detection of particular analytes. Thiazolo[5,4-d]thiazoles (TTZs) are an ideal type of heterocycles for fluorophores with π-bridge moieties demonstrating structure-function characteristics. LMOFs with excellent sensing properties can be constructed by incorporating heterocyclic aromatic thiazolo[5,4-d]thiazole into the framework. This study has elaborated on LMOFs containing thiazolo[5,4-d]thiazole unit for the detection of environmental contaminants, such as toxic anions, aromatic compounds, a
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Tokárová, Zita, Renáta Gašparová, Natália Kabaňová, Marcela Gašparová, and Róbert Balogh. "Hemetsberger–Knittel and Ketcham Synthesis of Heteropentalenes with Two (1:1), Three (1:2)/(2:1) and Four (2:2) Heteroatoms." Reactions 4, no. 2 (2023): 254–73. http://dx.doi.org/10.3390/reactions4020015.

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The synthetic methods leading to furo[3,2-b]pyrroles and thiazolo [5,4-d]thiazoles are reviewed herein. Furo-, thieno- and seleno [3,2-b]pyrroles are related to heteropentalenes, containing two heteroatoms in the entire structure, one each per core. The synthetic approach follows the Hemetsberger–Knittel protocol covering three reaction steps—the nucleophilic substitution of halogen-containing aliphatic carboxylic acid esters, Knoevenagel condensation and, finally, thermolysis promoting the intramolecular cyclocondensation to O,N-heteropentalene. The Hemetsberger–Knittel reaction sequence is a
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Drašar, Pavel, Vladimír Pouzar, Ivan Černý, George R. Pettit, and Miroslav Havel. "Synthesis and in vitro antimetabolic evaluation of some steroidal thiazoles." Collection of Czechoslovak Chemical Communications 54, no. 12 (1989): 3339–47. http://dx.doi.org/10.1135/cccc19893339.

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Steroidal thiazoles VI-XII have been synthesized. The starting bromoketones XVII and XX were prepared by bromination of pregnan-20-ones in position 21 with copper(II) bromide, and used for synthesis of the thiazole derivatives employing the Hantzch reaction. Preliminary biological evaluation of thiazoles I-XII against the P388 lymphocytic leukemia cell line showed growth inhibition values of ED50 2.9 and 7 μg/ml for thiazoles II and VII, respectively.
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Turov, Kostyantyn. "Anticancer evaluation of di- and trifunctional substituted 1,3-thiazoles." Ukr. Bioorg. Acta 2020, Vol. 15, N1 15, no. 1 (2020): 2–11. http://dx.doi.org/10.15407/bioorganica2020.01.002.

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Anticancer activity of a series of polyfunctional substituted 1,3-thiazoles has been studied within the international scientific program “NCI-60 Human Tumor Cell Lines Screen”. Screening was performed in vitro on 60 cell lines of lungs, kidneys, CNS, ovaries, prostate, and breast cancer, epithelial cancer, leukemia, and melanoma. The most effective compounds were those with a piperazine substituent at C2 of the 1,3-thiazole cycle: 1-(4-((4-methylphenyl)-sulfonyl)-2-phenyl-1,3-thiazol-5-yl)piperazine (average lg GI50 = -5.87, lg TGI = -5.54, lg LC50 = -5.21), 1-(2-(3,5-dimethyl-1H-pyrazol-1-yl)
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Ram, Sevak Verma*1 Nitin Mittal2 Bhumika Yogi3 Shikha Sharma4 Abhishek Mishra5. "A Review On Chemistry And Antimicrobial Activity Of Thiazole." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 1184–201. https://doi.org/10.5281/zenodo.10893122.

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The recent study classe of five-membered heterocyclic compounds is thiazoles. Several thiazoles, both synthetic and natural, and their derivatives exhibited strong biological activity. Thiazole derivatives exhibit strong antibacterial action against a variety of bacterial species & diseases because of their special characteristics. As a result, the current study assigns different thiazoles and there derivatives' antimicrobial activity. Through the use of many databases, every pertinent piece of literature has been examined. The important studies on the antibacterial activity of thiazole de
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Arshad, Mohammed F., Aftab Alam, Abdullah Ayed Alshammari, et al. "Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents." Molecules 27, no. 13 (2022): 3994. http://dx.doi.org/10.3390/molecules27133994.

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For many decades, the thiazole moiety has been an important heterocycle in the world of chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) electrons are free to move from one bond to other bonds rendering aromatic ring properties. On account of its aromaticity, the ring has many reactive positions where donor–acceptor, nucleophilic, oxidation reactions, etc., may take place. Molecules containing a thiazole ring, when entering physiological systems, behave unpredictably and reset the system differently. These molecules may activate/stop the biochemica
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Slyvka, N. Yu, L. M. Saliyeva, V. I. Zhylko, V. M. Tkachuk, and M. V. Vovk. "Synthesis and antioxidant activity of new 2-(2-oxoindoline-3-ylydene) substituted 5,6-dihydroimidazo[2,1-b]thiazolones and 6,7-dihydro-thiazolo[3,2-a]pyrimidinones." Voprosy Khimii i Khimicheskoi Tekhnologii, no. 1 (February 2025): 71–79. https://doi.org/10.32434/0321-4095-2025-158-1-71-79.

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The paper presents the results of the study on the interaction of 5,6-dihydroimidazo[2,1-b]thiazoles and 6,7-dihydrothiazolo[3,2-a]pyrimidines with isatin derivatives. It was established that the condensation of the indicated reagents occurs selectively upon heating and without the use of a catalyst with the formation of addition products, 2-(2-oxoindolin-3-ylidene)-5,6-dihydroimidazo[2,1-b]thiazole-3(2H)-ones 6a–d and 2-(2-oxoindolin-3-ylidene)-6,7-dihydro-2H-thiazolo[3,2-a]pyrimidin-3(5H)-ones 7a–c, the structure of which was rigorously proven by 1H NMR (13C) spectroscopy and chromatography-
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Dissertations / Theses on the topic "Thiazoles"

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Thom, Stephen M. "Synthetic studies with natural thiazoles and thiazolines." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334420.

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Higton, Sharon M. "Synthetic studies towards naturally occurring thiazoles and thiazolines." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240229.

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Turner, Gemma L. "Direct arylation of thiazoles." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/3188.

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An introduction to the thiazole ring system is presented together with a detailed, but non-exhaustive review of the rapidly emerging area of palladium-mediated directed arylation. The direct arylation of thiazole is also discussed together with our attempts to improve the established methods. A high-yielding, mild protocol has been developed for the functionalisation of the most electron-rich carbon-hydrogen bonds in a number of heterocyclic ring systems, this represents the first example of a C-H activation reaction being accomplished in aqueous media and allows access to a diverse range of f
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Boukraa, Sadok. "Préparation, réactivité et étude des propriétés fongistatiques et immunostimulantes d'amino-2 thiazoles et d'imidazo-(2,1-B) thiazoles." Besançon, 1987. http://www.theses.fr/1987BESA2030.

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Le travail se divise en deux grandes parties : la premiere concerne la preparation d'aryl-6 imidazo(2,1-b) thiazoles substitues en 3 par des chaines de type acetate d'ethyle, aroylmethyle. (beta -hydroxy beta -aryl)ethyle te arylethyle. Pour ce faire, il a ete necessaire de preparer les amino-2 thiazoles corespondants substitues par ces memes chaines en 4 afin de las opposer a des acetophenones omega -bromees. L'influence des substituants presents est discutee en vue d'aprehender l'evolution des reactions. La seconde partie concerne des essais en tant que fongistatiques et/ou immunostimulants
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Boukraa, Sadok. "Préparation, réactivité et étude des propriétés fongistatiques et immunostimulantes d'amino-2 thiazoles et d'imidazo-(2,1-b) thiazoles." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376032986.

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Baudrion, Christophe. "Synthèses et études structurales des bithiazoles." Aix-Marseille 3, 1991. http://www.theses.fr/1991AIX30087.

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Cette etude porte sur la synthese et l'analyse structurale des bithiazoles. Dans un premier temps la synthese de plusieurs derives halogeno, stannyl et silyl-thiazole a ete optimisee. Puis quatre des six bithiazoles ont pu etre separes par de nouvelles reactions de couplage avec des metaux de transition tels que le nickel ou le palladium. Une premiere analyse comparative de cinq bithiazoles a ensuite ete effectuee par r. M. N. #1h, #1#3c, infra-rouge, spectrometrie de masse et ultra-violet. Des calculs theoriques par mecanique moleculaire et par mecanique ondulatoire ont permis d'evaluer les b
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Fernandez, Xavier. "Réativité des thiazolidines, substances aromatisantes et parfumantes." Nice, 2001. http://www.theses.fr/2001NICE5672.

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Récemment identifiées à l'état de traces dans la goyave et le cupuaçu, les thiazolidines sont des intermédiaires clefs dans la biosynthèse des thiazolines et thiazoles, hétérocycles d'un grand intérêt dans le domaine de la chimie des arômes. Ce travail a pour objectif l'étude des thiazolidines et des réactions d'oxydation sélectives sur ces dernières. La première partie de cette étude complète les travaux existants sur les thiazolidines principalement en ce qui concerne la stéréochimie et l'étude de leur réaction d'isomérisation. Pour cela, nous nous sommes principalement appuyés sur la RMN (1
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梁曼儀 and Man-yee Leung. "Synthetic investigations into [delta]4-1, 2-thiazoline 1, 1-dioxides." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1985. http://hub.hku.hk/bib/B31207340.

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Uzelac, Eric James. "Thiazole vs. Thiophene: Heterocycle Effects on the Properties of Fused-Ring Conjugated Materials." Diss., North Dakota State University, 2017. https://hdl.handle.net/10365/29091.

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Conjugated polymers and related molecular materials comprise a field of materials chemistry focused on the development of semiconducting organic plastics that find use in applications such as organic solar cells and organic light-emitting diodes. The optical and electronic properties of these molecules, such as absorption and emission of light, can be tuned through engineering at the molecular level. However, many of the current molecules of choice suffer from high-lying frontier orbitals, which results in a mismatch of energy levels to common components of electronic devices along with potent
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Barbry, Didier. "Synthèse et étude structurale de thiazolidines substituées sur les positions 2, 4 ou 5." Lille 1, 1986. http://www.theses.fr/1986LIL10105.

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Synthèse de thiazolidines substituées par un ou plusieurs méthyle et par isopropyles, t-butyle ou phényle et éventuellement un ou plusieurs méthyle ; étude de structure en solution par RMN 1H, 13C, 15N et à l'état solide par diffraction Rx (pour la phényl-2 thiazolidine) ; discussion sur l'effet anomère
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Books on the topic "Thiazoles"

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Sowoidnich, Werner. Neue Chelate der Benzthiazol- und Benzobisthiazolreihe: Darstellung und spektroskopische Eigenschaften. Hartung-Gorre, 1989.

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Jenny, Christian-Johannes. Synthese und Reaktionen von 2-Thiazolin-5-thionen. [s.n.], 1986.

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Svadlenka, Anton. Thiazole: Synthesis and Reactions. Nova Science Publishers, Incorporated, 2020.

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Thiazole: Synthesis and Reactions. Nova Science Publishers, Incorporated, 2020.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 3. Wiley & Sons, Incorporated, John, 2008.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 1. Wiley & Sons, Incorporated, John, 2009.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 1. Wiley & Sons, Incorporated, John, 2008.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 2. Wiley & Sons, Incorporated, John, 2009.

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Metzger, Jacques V. Thiazole and Its Derivatives, Part 2. Wiley & Sons, Limited, John, 2007.

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Thiazole and Its Derivatives, Part 3. Wiley & Sons, Incorporated, John, 2009.

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Book chapters on the topic "Thiazoles"

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Rauf, Abdul, and Nida Nayyar Farshori. "Thiazoles." In SpringerBriefs in Molecular Science. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-1485-4_3.

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Begtrup, Mikael, and Christian Roussel. "Mesoionic Thiazoles." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187074.ch1.

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Wu, Yong-Jin. "Thiazoles and Benzothiazoles." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2012_78.

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Maga, Joseph A. "Thiazoles in Foods." In Fenaroli’s Handbook of Flavor Ingredients, 2nd ed. CRC Press, 2021. http://dx.doi.org/10.1201/9780429292439-10.

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Mak, Jeffrey Y. W., Weijun Xu, and David P. Fairlie. "Thiazoles in Peptides and Peptidomimetics." In Topics in Heterocyclic Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_176.

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Yurovskaya, M. A. "Fluorinated Oxazoles, Thiazoles and Selenazoles." In Fluorine in Heterocyclic Chemistry Volume 1. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04346-3_10.

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Chanon, M. "General Introduction to Protomeric Thiazoles." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187067.ch1.

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Elmore, J. Stephen, and Donald S. Mottram. "Extraction by Headspace Trapping onto Tenax of Novel Thiazoles and 3-Thiazolines in Cooked Beef." In ACS Symposium Series. American Chemical Society, 1998. http://dx.doi.org/10.1021/bk-1998-0705.ch006.

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Joule, J. A., K. Mills, and G. F. Smith. "1,3-Azoles: imidazoles, thiazoles and oxazoles: reactions and synthesis." In Heterocyclic Chemistry. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8_21.

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Dhadda, Surbhi, Nidhi Jangir, Shikha Agarwal, Arvnabh Mishra, and Dinesh Kumar Jangid. "Nanocatalysed Synthesis and Biological Significance of Imidazoles, Hydantoins, Oxazoles, and Thiazoles." In Nanocatalysis. CRC Press, 2022. http://dx.doi.org/10.1201/9781003141488-9.

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Conference papers on the topic "Thiazoles"

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Shuchi, Nuren, Tyler Adams, V. Paige Stinson, et al. "Complex Dielectric Function of Photochromic Thiazolothiazole Embedded Polymers Determined by Spectroscopic Ellipsometry." In CLEO: Applications and Technology. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/cleo_at.2024.jth2a.10.

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The complex dielectric function of photochromic thiazolo[5,4-d]thiazole embedded in polymer is reported in the spectral range from 0.8 to 2.5 eV. Strong absorption bands in the measured spectral range are observed depending upon its redox states.
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Zetlmeisl, Michael J. "Naphthenic Acid Corrosion and Its Control." In CORROSION 1996. NACE International, 1996. https://doi.org/10.5006/c1996-96218.

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Abstract This paper first presents a brief description of naphthenic acid corrosion and the main factors which influence its onset and severity. After a brief discussion of traditional control methods, it proceeds to a discussion of chemical inhibition, which is a relatively new control technique. Chemical inhibitors can be divided into two broad classifications: phosphorus-based and non-phosphorus-based. Three types of phosphorus-based inhibitors have been reported: amine-neutralized phosphate esters, alkaline earth phosphonate phenate sulfide plus trialkyl phosphate, and thiazolines plus di-
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Váry, Tomáš, Zita Tokárová, and Vojtech Nádaždy. "Energy resolved electrochemical impedance spectroscopy of furan-substitued thiazolo [5,4-d]thiazoles." In APPLIED PHYSICS OF CONDENSED MATTER (APCOM 2021). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0067189.

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Gomes, Paulo A. T. M., Diogo R. M. Moreira, Marcos V. O. Cardoso, et al. "New 1,3-Thiazoles Prepared Through Ultrasound Irradiation." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0214-1.

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Landeira, Lucía, Florencia Parpal, Eduardo Manta, Gloria Serra, and Laura Scarone. "Towards efficient methods to construct bis-oxa/thiazoles." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0082-1.

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Grybaitė, Birutė, Rita Vaickelionienė, Vytautas Mickevičius, Viktor Zvarych, and Volodymyr Novikov. "Synthesis and antimicrobial activity of novel 2,4-disubstituted thiazoles." In Chemical technology and engineering. Lviv Polytechnic National University, 2019. http://dx.doi.org/10.23939/cte2019.01.249.

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Mavlianberdiev, A. R., A. V. Yadykov, V. Z. Shirinian, et al. "A convenient synthesis of condensed thiazoles as promising tubulin/Tdp-1 bi-inhibitors." In ACTUAL PROBLEMS OF ORGANIC CHEMISTRY AND BIOTECHNOLOGY (OCBT2020): Proceedings of the International Scientific Conference. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0069495.

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PINILLA PEÑA, Diana Carolina, María Isabel SOARES, Liliana Beatriz PIERELLA, Teresa María V. D. PINHO E MELO, and Walter José PELÁEZ. "THERMAL REACTIONS OF 2,2-DIOXO-1H,3H-PYRROLO[1,2-C]THIAZOLES STUDIED FROM GREEN METRICS." In Second Southern Science Conference - 2024. Araucária - Associação Científica, 2024. https://doi.org/10.48141/sscon_61_2024.pdf.

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The concept of Green Chemistry, introduced 25 years ago by the U.S. Environmental Protection Agency, aims to assess the sustainability of chemical processes. During this time, Dr. Barry Trost developed Atom Economy, which measures how "green" a reaction is using parameters such as Atom Economy (%AE), Mass Intensity (MI), and Reaction Mass Efficiency (RME). Recently, the focus has shifted to evaluating flash vacuum pyrolysis reactions under these principles. This study presents results from evaluating the thermal stability of 2,2-dioxo-1h,3h-pyrrolo[1,2-c]thiazoles, which are of pharmacological
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Nagarjuna, Ummadi, Gundala Sravya, S. Durgamma, Adivireddy Padmaja, and Grigory V. Zyryanov. "Synthesis of a new class of heteroaryl dipyrazolyl carbothioamides and heteroaryl dipyrazolyl thiazoles and evaluation as antioxidants." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087371.

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Sydorenko, Nadiya, Ramil Baiazitov, Soongyu Choi, et al. "Abstract 2529: Optimization of small molecules targeting BMI1 protein expression. Part 1. Amino-thiazoles: the first-in-class highly potent inhibitors of BMI1 protein." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2529.

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