Relevant bibliographies by topics / Thiazolopyrimidine

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Academic literature on the topic 'Thiazolopyrimidine'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Thiazolopyrimidine"

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Tolba, Mahmoud S., Mostafa Sayed, Shaban A. A. Abdel-Raheem, Taher A. Gaber, Adel M. Kamal El-Dean, and Mostafa Ahmed. "Synthesis and spectral characterization of some new thiazolopyrimidine derivatives." Current Chemistry Letters 10, no. 4 (2021): 471–78. http://dx.doi.org/10.5267/j.ccl.2021.4.004.

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Thiazolopyrimidnes are considered one of the most interesting classes in heterocyclic chemistry due to their pharmaceutical importance. Herein, we report the synthesis of some new heterocyclic compounds containing thiazolopyrimidine starting from compound (1) which was previously prepared in literature. The starting compound was allowed to react with different alkylating agents such as chloroacetone, chloroacetyl chloride, and phenacyl bromide to afford derivatives (2-4). Compound (5), benzylidene derivative, was obtained by the reaction of compound (2) with benzaldehyde while amino-dicarbonit
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2

El-Mahdy, Kamelia. "Synthesis of Some New Tetracyclic Pyrimidine Derivatives Using Exocyclic α,β-Unsaturated Ketone and Evaluation of Their Antitumor Activities". JOURNAL OF ADVANCES IN CHEMISTRY 12, № 8 (2016): 311–17. http://dx.doi.org/10.24297/jac.v12i8.2840.

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Thiazolopyrimidine 2 was obtained from the reaction of dihydropyrimidinone with chloroacetic acid and benzaldehyde. Thiazolopyrimidine 2 containing an α,β-unsaturated ketonic function [-CH=CH-CO-] has been used as a component of Michael addition with an equimolar amount of dinucleophiles to give a series of novel tetracyclic pyrimidine derivatives. Treatment of thiazolopyrimidine 2 with uracil, aminotriazole, cyanoacetic acid hydrazide, o-phenylenediamine or diaminopyridine afforded the corresponding pyridopyrimidine, triazolopyrimidine, pyrazolone, benzodiazepine and triazepine derivative, re
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El-Mahdy, Kamelia. "Synthesis of Some New Tetracyclic Pyrimidine Derivatives Using Exocyclic α,β-Unsaturated Ketone and Evaluation of Their Antitumor Activities". JOURNAL OF ADVANCES IN CHEMISTRY 4, № 1 (2008): 311–17. http://dx.doi.org/10.24297/jac.v4i1.960.

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Thiazolopyrimidine 2 was obtained from the reaction of dihydropyrimidinone with chloroacetic acid and benzaldehyde. Thiazolopyrimidine 2 containing an α,β-unsaturated ketonic function [-CH=CH-CO-] has been used as a component of Michael addition with an equimolar amount of dinucleophiles to give a series of novel tetracyclic pyrimidine derivatives. Treatment of thiazolopyrimidine 2 with uracil, aminotriazole, cyanoacetic acid hydrazide, o-phenylenediamine or diaminopyridine afforded the corresponding pyridopyrimidine, triazolopyrimidine, pyrazolone, benzodiazepine and triazepine derivative, re
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4

AGGARWAL, S., M. DEVGUN, R. NARANG, S. LAL, A. C. RANA, and R. GOYAL. "Thiazolopyrimidines: A Retrospective Study of Synthesis, Structure-Activity Relationship and Diverse Pharmacological Actions." Asian Journal of Chemistry 34, no. 3 (2022): 519–30. http://dx.doi.org/10.14233/ajchem.2022.23448.

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Thiazolopyrimidine is a nitrogen and sulphur containing heterocyclic aromatic molecule. The bicyclic compound is made by fusing two aromatic rings, thiazole and pyrimidine and replacing one carbon atom with nitrogen and sulphur. The current present work covers a wide range of methods for synthesizing thiazolopyrimidine and its derivatives using a variety of catalysts, solvent medium and microwave irradiation with a goal of achieving a high yield and rapid separation of the product. This article describes the evolution of thiazolopyrimidine as antimicrobial, antiviral, anti-Parkinson, anticance
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5

Rasovic, Aleksandar. "The interaction between 4-oxothiazolidine-2-ylidene thioamides and iodine: a regioselective two-component 4-oxothiazolidine-2-ylidene thioamide to thiazolo[3,2-c]pyrimidine transformation mediated by iodine." Journal of the Serbian Chemical Society, no. 00 (2025): 1. https://doi.org/10.2298/jsc231207001r.

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This study investigated the interaction between selected 4- oxothiazolidine-2-ylidene thioamides 2a-c and iodine in acetone. The interaction followed two main reaction pathways: (1) iodine-mediated cyclization resulting in the formation of thiazolopyrimidine 7, and (2) electrophilic iodine attack on the thioamide sulfur atom, producing a complex mixture of iodine adducts. Due to the equilibrium of Z/E isomerization being strongly shifted to the Z-isomer in polar solvents, only the thioamide (E)-2b successfully formed thiazolopyrimidine 7. The other two derivatives, (Z)-2a and (Z)-2c, followed
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Mousavi-Moghadam, Farah Sadat, and Mohammad Ali Ghasemzadeh. "Preparation and Characterization of FeCo2O4 Nanoparticles: A Robust and Reusable Nanocatalyst for the Synthesis of 3,4-Dihydropyrimidin- 2(1H)-thiones and Thiazolopyrimidines." Current Nanoscience 15, no. 6 (2019): 637–46. http://dx.doi.org/10.2174/1573413714666180808163714.

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Background:The present research describes a mild and efficient method for the synthesis of 3,4-dihydropyrimidine-2(1H)-thiones and thiazolopyrimidine via multi-component reactions using FeCo2O4 nanoparticles. It was found that FeCo2O4 nanoparticles act as a powerful and effective catalyst. The prepared catalyst was characterized by the various spectroscopic techniques.Objective:The three-component reaction of thiourea, aromatic aldehydes and ethyl acetoacetate was catalyzed by FeCo2O4 nanoparticles. Next, the prepared 3,4-dihydropyrimidin-2(1H)-thiones were applied for the preparation of thiaz
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7

Vasilkova, N. O., A. V. Nikulin, and A. P. Krivenko. "Synthesis and Structure of Thiazolopyrimidine Derivatives." Russian Journal of Organic Chemistry 56, no. 6 (2020): 990–93. http://dx.doi.org/10.1134/s1070428020060044.

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8

Mobinikhaledi, A., N. Forughifar, and F. Goodarzi. "Synthesis of Some Bicyclic Thiazolopyrimidine Derivatives." Phosphorus, Sulfur, and Silicon and the Related Elements 178, no. 12 (2003): 2539–43. http://dx.doi.org/10.1080/714040967.

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Banu, Noor Afshan, and V. Bheema Raju. "Ethyl 7-methyl-3-oxo-5-phenyl-2-(2,4,6-trimethoxybenzylidene)-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate." Acta Crystallographica Section E Structure Reports Online 68, no. 4 (2012): o1213. http://dx.doi.org/10.1107/s1600536812012354.

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In the title compound, C26H26N2O6S, the benzene ring is positioned axially to the thiazolopyrimidine ring and bisects it with a dihedral angle of 80.94 (7)°. The pyrimidine ring adopts a flattened boat conformation. In the crystal, pairs of bifurcated C—H...O hydrogen bonds link the molecules into chains along thecaxis.
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NAGARAJAIAH, H., I. M. KHAZI, and NOOR SHAHINA BEGUM. "Synthesis, characterization and biological evaluation of thiazolopyrimidine derivatives." Journal of Chemical Sciences 124, no. 4 (2012): 847–55. http://dx.doi.org/10.1007/s12039-012-0271-z.

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Book chapters on the topic "Thiazolopyrimidine"

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Hatvate, Navnath Tulshiram, and Mukta Vivek Lele. "Synthesis, Properties, and Bioactivity of Thiazolopyrimidines." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch007.

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Thiazolopyrimidines are the fusion of thiazoles and pyrimidines heterocyclic rings, which has attracted much attention from medicinal and organic chemists because of its wide range of applications. Thiazolopyrimidines have applications in the pharmaceutical and agricultural fields, including analgesic, anti-inflammatory, herbicidal, antifungal, antimicrobial, antitumor, and antiparasitic properties. This chapter reviews the chemistry, different methods of synthesis and bioactivities of Thiazolopyrimidines. In addition, the patent and current clinical trials were also updated.
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Conference papers on the topic "Thiazolopyrimidine"

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El-Khouly, Omar A., Dina I. A. Othman, Amany S. Mostafa, and Mohammed A. M. Massoud. "Thiazolopyrimidine as a Promising Anticancer Pharmacophore: In Silico Drug Design, Molecular Docking and ADMET Prediction Studies." In ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13313.

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Marques, M. Matilde, Mohamed Mahgoub, Awatef Elmaghraby, et al. "Synthesis and characterization of 2-arylidene derivatives of thiazolopyrimidines with potential biological activity." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-b008.

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You might also be interested in the extended bibliographies on the topic 'Thiazolopyrimidine' for particular source types:
Journal articles
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