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Relevant bibliographies by topics / Thiepine

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Journal articles

Academic literature on the topic 'Thiepine'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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Journal articles on the topic "Thiepine"

1

Nishino, Keitaro, Masanobu Takagi, Teruhisa Kawata, Ichiro Murata, Junji Inanaga, and Kazuhiro Nakasuji. "Thiepine-iron tricarbonyl: stabilization of thermally labile parent thiepine by transition metal complexation." Journal of the American Chemical Society 113, no. 13 (1991): 5059–60. http://dx.doi.org/10.1021/ja00013a051.

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2

Yoshinari, Nobuto, and Takumi Konno. "5,7-Dihydrodibenzo[c,e]thiepine." Acta Crystallographica Section E Structure Reports Online 65, no. 4 (2009): o774. http://dx.doi.org/10.1107/s1600536809008769.

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3

Murata, Ichiro. "Some New Aspects of Thiepine and Thiazepine Chemistry." Phosphorus, Sulfur, and Silicon and the Related Elements 43, no. 3-4 (1989): 243–59. http://dx.doi.org/10.1080/10426508908040289.

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4

Bozinovic, Nina, Irena Novakovic, Sladjana Kostic-Rajacic, Igor Opsenica, and Bogdan Solaja. "Synthesis and antimicrobial activity of azepine and thiepine derivatives." Journal of the Serbian Chemical Society 80, no. 7 (2015): 839–52. http://dx.doi.org/10.2298/jsc150116013b.

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A series of new 5H-pyridobenzazepine and pyridobenzothiepine derivatives was synthesized by Pd-catalyzed formation of C-N and C-S bonds. All synthesized compounds were tested for their in vitro antimicrobial activity. The 5H-pyridobenzazepine derivatives showed better antibacterial and antifungal activity than corresponding 5H-dipyridoazepine analogs. Among the synthesized azepines, derivative 8 displayed potent activity against tested bacteria (MIC = 39-78 ?g/mL), while azepine 12 showed promising antifungal activity (MIC = 156-313 ?g/mL). The synthesized thiepine derivatives exhibited weak antibacterial activity, but showed pronounced antifungal activity.

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5

Zhang, Hai-Quan, Bao-Li, Guang-Di Yang, and Yu-Guang Ma. "3,9-Dibromo-6,7-dihydro-5H-dibenzo[c,e]thiepine." Acta Crystallographica Section E Structure Reports Online 64, no. 6 (2008): o1027. http://dx.doi.org/10.1107/s1600536808013226.

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6

Foubelo, Francisco, Benjamín Moreno, Tatiana Soler, and Miguel Yus. "Reductive ring opening of dihydrodibenzothiepine and dihydrodinaphtho-oxepine and -thiepine." Tetrahedron 61, no. 38 (2005): 9082–96. http://dx.doi.org/10.1016/j.tet.2005.07.042.

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7

Edwards, David J., Robin G. Pritchard, and Timothy W. Wallace. "Fine-tuning of biaryl dihedral angles: structural characterization of five homologous three-atom bridged biphenyls by X-ray crystallography." Acta Crystallographica Section B Structural Science 61, no. 3 (2005): 335–45. http://dx.doi.org/10.1107/s0108768105006713.

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The homologous series of three-atom bridged biaryls comprising 5,7-dihydro-1,2,3,9,10,11-hexamethoxydibenzo[c,e]oxepine, 6,7-dihydro-1,2,3,9,10,11-hexamethoxy-6-methyl-5H-dibenzo[c,e]azepinium chloride, 5,7-dihydro-1,2,3,9,10,11-hexamethoxydibenzo[c,e]thiepine, and the 6-oxide and 6,6-dioxide derivatives of the latter have been characterized by X-ray crystal structure analysis. Within this series the endocyclic and exocyclic biaryl dihedral angles vary over 10° ranges, reflecting the changing balance of intramolecular (steric, geometric) and intermolecular (crystal packing) forces, the former being potential control elements for fine-tuning the helicity of the biaryl system.

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8

Higashi, Y., Y. Momotani, E. Suzuki, and T. Kaku. "Clinical and EEG Studies of Zotepine, a Thiepine Neuroleptic, on Schizophrenic Patients." Pharmacopsychiatry 20, S 1 (1987): 8–11. http://dx.doi.org/10.1055/s-2007-1017124.

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9

Foubelo, Francisco, Benjamín Moreno, and Miguel Yus. "Reductive opening of 2,7-dihydrodinaphthoxepine and thiepine: easy regioselective preparation of 2,2′-difunctionalised binaphthyls." Tetrahedron Letters 45, no. 49 (2004): 8983–86. http://dx.doi.org/10.1016/j.tetlet.2004.10.041.

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10

Bøgesø, Klaus P., and Michael Bech Sommer. "The effect of aromatic substitution on neuroleptic activity in 1-piperazino-3-phenylindans. A comparison based on a new D-2 receptor model with corresponding 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins." Collection of Czechoslovak Chemical Communications 56, no. 11 (1991): 2456–67. http://dx.doi.org/10.1135/cccc19912456.

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The validity of a new dopamine D-2 receptor interaction model based on conformational analysis and least-squares superimposition studies of the indan derivative tefludazine and the thiepin derivative octoclothepin was further tested by comparison of the effect of aromatic substitution on D-2 antagonistic activity in two series of indan and thiepin derivatives. The indan series include new derivatives substituted in the 4-, 7-, 2’- and 3’-position. The substitution effects were largely parallel with one important exception: Only 6-substituted indans have significant neuroleptic activity while both 8- and 7-substituted thiepin derivatives have neuroleptic activity. In indans additional fluorination in the 2’- or 4’-position is demanded to give potent neuroleptic activity, while a 3’-fluoro-substituted derivative was inactive. Fluorination is not necessary in thiepins although 3-fluoro derivatives have a significant prolonged duration of action. Considering the differences in physico-chemical properties, metabolism and pharmacokinetics between the two series, the largely parallel substitution effects support the new D-2 receptor model.

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