Academic literature on the topic 'Thiol disulfide homeostasis'

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Journal articles on the topic "Thiol disulfide homeostasis"

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Georgescu, Simona Roxana, Cristina Iulia Mitran, Madalina Irina Mitran, et al. "Thiol-Disulfide Homeostasis in Skin Diseases." Journal of Clinical Medicine 11, no. 6 (2022): 1507. http://dx.doi.org/10.3390/jcm11061507.

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Oxidative stress represents the imbalance between oxidants and antioxidants and has been associated with a wide range of diseases. Thiols are the most important compounds in antioxidant defense. There is an equilibrium between thiols and their oxidized forms, disulfides, known as dynamic thiol-disulfide homeostasis (TDH). In 2014, Erel and Neselioglu developed a novel automated assay to measure thiol and disulfide levels. Subsequently, many researchers have used this simple, inexpensive and fast method for evaluating TDH in various disorders. We have reviewed the literature on the role of TDH
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Fadime, Kilinc, Sener Sertac, Akbas Ayse, Neselioglu Salim, Erel Ozcan, and Aktas Akin. "Investigation of Dynamic Thiol-Disulfide Homeostasis in Alopecia Areata Patients." British Journal of Medicine & Medical Research 21, no. 6 (2017): 1–7. https://doi.org/10.9734/BJMMR/2017/33535.

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<strong>Background: </strong>Thiols are antioxidant, organic compounds containing sulfhydryl group on their active sites. They have important roles on preventing oxidative stress. The thiol disulfide homeostasis has a vital importance in organism. Thiol disulfide imbalance is an early indicator of oxidative stress. Alopecia areata is an autoimmune skin disorder characterized with scar-free hair loss. Its pathogenesis is still unclear. Thiol disulfide homeostasis in these patients has not been studied at all. <strong>Objective: </strong>To evaluate the thiol disulfide homeostasis in alopecia ar
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YILMAZ, Yücel, Şaban KELEŞOĞLU, Kemal TEKİN, et al. "A New Biomarker in The Distinction Between Stable Coronary Artery Disease and Acute Coronary Syndrome:Thiols." Journal of Contemporary Medicine 12, no. 4 (2022): 1–6. http://dx.doi.org/10.16899/jcm.981853.

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Backraund; Thiols are important elements for oxidation reactions and under oxidative stress. The aim of this study was to determine thiole levels, an antioxidative marker in CAD patients with stable and acute coronary syndrome. &#x0D; Methods; 210 of the patients included in the study were diagnosed with acute coronary syndrome (ACS), 205 consisted of patients with stable angina pectoris (SAP). Thiol groups levels and thiol/disulphide homeostasis was measured by spectrophotometrically. &#x0D; Results: Native thiol and total thiol levels, disulfide/natural thiol and disulfide/total thiol ratios
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Asil, Mehmet, Ramazan Dertli, Murat Biyik, et al. "Dynamic thiol-disulfide homeostasis is disturbed in patients with non-alcoholic fatty liver disease." LaboratoriumsMedizin 42, no. 1-2 (2018): 31–38. http://dx.doi.org/10.1515/labmed-2017-0018.

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AbstractBackground:Oxidative stress has been implicated in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Plasma thiols are major defense mechanisms against oxidative stress and undergo oxidation to form disulfides under oxidative conditions. This study was conducted to investigate thiol-disulfide homeostasis in NAFLD patients.Methods:Thirty patients with biopsy proven non-alcoholic steatohepatitis (NASH), 40 patients with simple steatosis and 50 healthy controls were included in the study. Serum total and native thiol concentrations and serum disulfide concentration were measu
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Ozyurt, Songul, Neslihan Ozcelik, Bilge Yilmaz Kara, et al. "Evaluation of Thiol/Disulfide Homeostasis in Bronchiectasis." Canadian Respiratory Journal 2022 (January 29, 2022): 1–6. http://dx.doi.org/10.1155/2022/8340450.

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Purpose. Thiols are sulfhydryl-containing organic compounds that have an important role in preventing cellular oxidative stress. This study compares the blood oxidative stress marker levels in bronchiectasis cases during their stable periods with healthy controls. Materials and Methods. Seventy-seven patients (49 patients with stable bronchiectasis/28 healthy controls), followed up by the chest disease clinic, were included in the study. Peripheral blood thiol-disulfide parameters (NT: native thiol (−SH); TT: total thiol (−SH + SS); SS: disulfide (−SS); SS-SH: disulfide/native thiol index; SS-
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Yazıcı, Mutlu U., Ganime Ayar, Semra Çetinkaya, et al. "Evaluation of Thiol/Disulfide Homeostasis in Pediatric Patients with Diabetic Ketoacidosis." Combinatorial Chemistry & High Throughput Screening 23, no. 3 (2020): 185–90. http://dx.doi.org/10.2174/1386207323666200218114331.

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Aim and Objective: This study aimed to investigate the value of Thiol/Disulfide homeostasis in pediatric diabetic ketoacidosis patients suffering from type 1 diabetes mellitus. Materials and Methods: This study featured children who were diagnosed with diabetic ketoacidosis and who were consecutively admitted to pediatric intensive care within one year of their diagnosis. Thiol/disulfide homeostasis was evaluated in 45 pediatric patients suffering from DKA, as well as 45 healthy controls of parallel gender and age. Thiol/disulfide homeostasis parameters were measured using a novel automated me
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Matei, Clara, Simona Roxana Georgescu, Ilinca Nicolae, et al. "Variations of Thiol–Disulfide Homeostasis Parameters after Treatment with H1-Antihistamines in Patients with Chronic Spontaneous Urticaria." Journal of Clinical Medicine 10, no. 13 (2021): 2980. http://dx.doi.org/10.3390/jcm10132980.

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Background. The pathogenesis of chronic spontaneous urticaria involves metabolic, immunological, and psychological factors. The thiol–disulfide exchange reactions could be a mechanism to counteract oxidative stress in patients with chronic spontaneous urticaria. Objective: The assessment of thiol–disulfide homeostasis parameters (TDHPs) according to disease severity and the influence of H1-antihistamine therapy in patients with chronic spontaneous urticaria. Material and method. We have included 30 patients with chronic spontaneous urticaria in the study and we have determined the levels of na
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Bayatkara Yilmaz, Tugba, Elif Karalı, Özgür Mehmet Yis, and Akif Güneş. "Dynamic Thiol / Disulfide Homeostasis In Patients With Nasal Polyps And The Effects Of Smoking On Homeostasis Parameters." Abant Medical Journal 14, no. 1 (2025): 19–27. https://doi.org/10.47493/abantmedj.1594807.

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Abstract Objective: The study aimed to determine the dynamic thiol/disulfide homeostasis for measuring oxidative stress and the impacts of smoking on these parameters in nasal polyps (NP) patients. Materials and methods: A total of forty NP patients and 36 healthy volunteers participated in the current study. Participants were categorized into two groups: 20 smokers and 20 non-smokers. Erel and Neşelioğlu developed an automated method to analyze thiol-disulfide homeostasis parameters in samples of serum from the participants. Groups were compared. Each parameter related to thiol/disulfide home
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Pektaş, Gökhan, Suzan Pektaş, Aynure Öztekin, et al. "Dynamic thiol/disulfide homeostasis in serum of patients with generalized vitiligo." Archives of Biological Sciences 71, no. 1 (2019): 55–62. http://dx.doi.org/10.2298/abs181003047p.

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Vitiligo is a multifactorial disorder commonly associated with hypo-/depigmentation in the skin and may influence both children and adults psychologically because of the notable leopard-skin-like appearance. This study was designed to investigate the thiol/disulfide homeostasis in patients with generalized vitiligo and to determine its relationship with some of the demographical characteristics. Seventy-six generalized vitiligo patients and 67 healthy individuals were included in the study. Blood serum native thiol, disulfide and total thiol concentrations, together with some hematological par
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Kazanci, Elif Guler, Deniz Guven, Ayse Oren, Yasemin Ustundag, Ozcan Erel, and Funda Eren. "Thiol-disulfide homeostasis in children with febrile neutropenia." Atlantic Journal of Medical Science and Research 2, no. 2 (2022): 20–24. http://dx.doi.org/10.55358/atjmed.2022.05.06.

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Aim: The body’s antioxidant system processes rely on thiol-disulfide equilibrium to function correctly. The purpose of this study was to look into dynamic thiol/disulfide homeostasis (TDH) as an endogenous antioxidant indicator in febrile neutropenic (FN) children with acute lymphoblastic leukemia (ALL). Materials and methods: The study included 66 acute lymphoblastic leukemia patients, including 33 with FN and 33 controls. Both groups were compared for TDH and ischemia-modified albumin (IMA). TDH parameters were assessed using a unique spectrophotometric approach disclosed earlier by Neşelioğ
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Book chapters on the topic "Thiol disulfide homeostasis"

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Yazar, Hayrullah, Yıldırım Kayacan, and Özcan Erel. "Thiol-Disulfide Homeostasis as an Oxidative Stress Indicator." In Biomarkers in Disease: Methods, Discoveries and Applications. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-07389-2_47.

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Bernic, Jana, Angela Ciuntu, Elena Hanganu, et al. "Thiol-Disulfide Homeostasis in Kidney Tumors in Children." In IFMBE Proceedings. Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-42782-4_32.

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Conference papers on the topic "Thiol disulfide homeostasis"

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Arguder, Emine, Hatice Kılıç, Ebru Parlak, et al. "Thiol Disulfide Homeostasis in Obstructive sleep apnoea syndrome (OSAS)- Preliminary report." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2318.

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Sahingoz, E., B. Nacir, M. Alisik, E. Ogus, O. Erel, and H. Genc. "THU0509 The role of thiol-disulfide homeostasis in the etiopathogenesis of fibromyalgia." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5754.

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Can Sandikci, S., S. Colak, A. Omma, et al. "SAT0670 Dynamic thiol/disulfide homeostasis as a novel oxidative marker in behÇet’s disease." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5278.

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Ramasli Gursoy, Tugba, Ayse Tana Aslan, Zeynep Reyhan Onay, Tugba Sismanlar Eyuboglu, Salim Neselioglu, and Ozcan Erel. "Evaluation of dynamic thiol disulfide homeostasis in children with stable primary ciliary dyskinesia." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa1010.

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