Relevant bibliographies by topics / Thiol-disulfide metabolism

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  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Thiol-disulfide metabolism'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Thiol-disulfide metabolism"

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Ergin, Merve, Cevdet Aydin, Emine Feyza Yurt, Bekir Cakir, and Ozcan Erel. "The Variation of Disulfides in the Progression of Type 2 Diabetes Mellitus." Experimental and Clinical Endocrinology & Diabetes 128, no. 02 (2018): 77–81. http://dx.doi.org/10.1055/s-0044-100376.

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Abstract Aim The purpose of this study was to examine thiol-disulfide balance in patients with type 2 diabetes mellitus. Methods This study included 32 subjects with known type 2 diabetes mellitus without complications, 30 patients with type 2 diabetes mellitus with complications, 28 newly diagnosed patients with type 2 diabetes mellitus, and 45 healthy individuals. Thiol-disulfide profile tests were quantified in all groups. Results Compared to the control group, patients in each of the diabetic groups had significantly lower native and total thiol levels, higher disulfide levels, and higher
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Vogelsang, Lara, and Karl-Josef Dietz. "Regulatory thiol oxidation in chloroplast metabolism, oxidative stress response and environmental signaling in plants." Biochemical Journal 477, no. 10 (2020): 1865–78. http://dx.doi.org/10.1042/bcj20190124.

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The antagonism between thiol oxidation and reduction enables efficient control of protein function and is used as central mechanism in cellular regulation. The best-studied mechanism is the dithiol-disulfide transition in the Calvin Benson Cycle in photosynthesis, including mixed disulfide formation by glutathionylation. The adjustment of the proper thiol redox state is a fundamental property of all cellular compartments. The glutathione redox potential of the cytosol, stroma, matrix and nucleoplasm usually ranges between −300 and −320 mV. Thiol reduction proceeds by short electron transfer ca
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Ondarza, Raul N. "Enzyme regulation by biological disulfides." Bioscience Reports 9, no. 5 (1989): 593–604. http://dx.doi.org/10.1007/bf01119803.

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More than a dozen enzymes have been found to be activated or inhibited in vitro by disulfide-exchange between the protein and small-molecule disulfides. Accordingly, thiol/disulfide ratio changes in vivo may be of great importance in the regulation of cellular metabolism. An awareness of this regulatory mechanism in both host cells and parasites, coupled with information on the presence or absence of key enzymes, may lead to rational drug design against certain diseases involving thiol intermediates, including trypanosomiasis.
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Moriarty-Craige, Siobhan E., and Dean P. Jones. "EXTRACELLULAR THIOLS AND THIOL/DISULFIDE REDOX IN METABOLISM." Annual Review of Nutrition 24, no. 1 (2004): 481–509. http://dx.doi.org/10.1146/annurev.nutr.24.012003.132208.

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Dietz, Karl-Josef, and Rüdiger Hell. "Thiol switches in redox regulation of chloroplasts: balancing redox state, metabolism and oxidative stress." Biological Chemistry 396, no. 5 (2015): 483–94. http://dx.doi.org/10.1515/hsz-2014-0281.

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Abstract In photosynthesizing chloroplasts, rapidly changing energy input, intermediate generation of strong reductants as well as oxidants and multiple participating physicochemical processes and pathways, call for efficient regulation. Coupling redox information to protein function via thiol modifications offers a powerful mechanism to activate, down-regulate and coordinate interdependent processes. Efficient thiol switching of target proteins involves the thiol-disulfide redox regulatory network, which is highly elaborated in chloroplasts. This review addresses the features of this network.
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Sardari, Veronica, Valeriana Pantea, Aurelian Gulea, et al. "Thiol-disulfide metabolism in kidney tissue at the administration of some copper coordination compounds." Moldovan Medical Journal 63 (2) (May 30, 2020): 12–17. https://doi.org/10.5281/zenodo.3865976.

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<strong>Background: </strong>Thiol-disulfide metabolism is essential for normal function of the organism. Thus the interest of the scientists in this area of research continues to grow. <strong>Material and methods: </strong>Copper coordination compounds (CCC), derivatives of thiosemicarbaside (CMD-4, CMJ-33, CMT-67), action on thiol-disulfide metabolism in the healthy <em>Ratta albicans</em> kidneys were studied. The animals were divided in 6 groups of 7 rats each. The control group included healthy rats which were injected i/m physiological solution 3 times a week, for 30 days. The rats from
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Ene, Corina Daniela, Mircea Nicolae Penescu, Simona Roxana Georgescu, Mircea Tampa, and Ilinca Nicolae. "Posttranslational Modifications Pattern in Clear Cell Renal Cell Carcinoma." Metabolites 11, no. 1 (2020): 10. http://dx.doi.org/10.3390/metabo11010010.

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Posttranslational modifications are dynamic enzymatic-mediated processes, regulated in time and space, associated with cancer development. We aimed to evaluate the significance of posttranslational modifications in the pathogenesis of clear cell renal cell carcinoma. The authors developed a prospective, observational study during a period of three years and included 55 patients with localized renal cell carcinoma and 30 heathy subjects. Glycosylation, nitration and carbonylation, thiol-disulfide homeostasis, methylation, phosphorylation and proteolytic cleavage were evaluated in the serum of t
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Gerna, Davide, Thomas Roach, Erwann Arc, et al. "Redox poise and metabolite changes in bread wheat seeds are advanced by priming with hot steam." Biochemical Journal 475, no. 23 (2018): 3725–43. http://dx.doi.org/10.1042/bcj20180632.

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Fast and uniform germination is key to agricultural production and can be achieved by seed ‘priming’ techniques. Here, we characterised the responses of bread wheat (Triticum aestivum L.) seeds to a hot steam treatment (‘BioFlash’), which accelerated water uptake, resulting in faster germination and seedling growth, typical traits of primed seed. Before the completion of germination, metabolite profiling of seeds revealed advanced accumulation of several amino acids (especially cysteine and serine), sugars (ribose, glucose), and organic acids (glycerate, succinate) in hot steam-treated seeds,
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Ates, Ihsan, Mustafa Kaplan, Bayram Inan, et al. "How does thiol/disulfide homeostasis change in prediabetic patients?" Diabetes Research and Clinical Practice 110, no. 2 (2015): 166–71. http://dx.doi.org/10.1016/j.diabres.2015.09.011.

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Kulinsky, V. I., and L. S. Kolesnichenko. "The glutathione system. II. Other enzymes, thiol-disulfide metabolism, inflammation, and immunity, functions." Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 3, no. 3 (2009): 211–20. http://dx.doi.org/10.1134/s1990750809030019.

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Dissertations / Theses on the topic "Thiol-disulfide metabolism"

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Akam, Eman Abureida, and Eman Abureida Akam. "Disulfide-Masked Prochelators Targeting the Iron Metabolism of Cancer: Design, Synthesis, and Biological Investigations." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/623183.

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Iron is the most abundant transition metal found in living systems and plays a crucial role in DNA biosynthesis. To accommodate higher replication rates, cancer cells require higher amounts of iron compared to non-neoplastic counterparts. This higher demand for iron renders cancer cells susceptible to iron deprivation, and exposure to iron chelators leads to growth arrest and cell death. Iron chelation strategies employing a wide variety of iron-binding scaffolds are currently under investigation for use in cancer treatment. Although these chelation approaches are effective against several can
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Book chapters on the topic "Thiol-disulfide metabolism"

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Murphy, Elaine. "Cognitive and Behavioral Manifestations of Disorders of Homocysteine Metabolism." In Cognitive and Behavioral Abnormalities of Pediatric Diseases. Oxford University Press, 2010. http://dx.doi.org/10.1093/oso/9780195342680.003.0041.

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This chapter reviews the metabolism of homocysteine and its associated defects, focusing on the clinical manifestations of cognitive and behavioral disturbances. The terminology of homocysteine and its derivatives can be confusing, so I begin by clarifying that. Next, the metabolism of homocysteine is outlined, followed by discussion of the disorders of homocysteine transsulfuration. Vitamin B12 (cobalamin, CBL) is important in the effective metabolism of homocysteine and thus defects of CBL absorption, transport, and intracellular transport are also discussed. Finally, disorders of remethylat
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Journal articles
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