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1

Katritsis, Demosthenes G., Bernard J. Gersh, and A. John Camm. Thoracic aortic aneurysms and other conditions. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199685288.003.1638_update_003.

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2

Gardiner, Matthew D., and Neil R. Borley. Cardiothoracic surgery. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199204755.003.0002.

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This chapter begins by discussing the basic principles of cardiac physiology and respiratory physiology, before focusing on the key areas of knowledge, namely congenital heart disease, coronary artery bypass grafting, heart valve disease, thoracic aortic dissection, thoracic aortic aneurysm, miscellaneous cardiac and mediastinal conditions, lung cancer, and miscellaneous thoracic conditions. The chapter concludes with relevant case-based discussions.
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3

1956-, Calligaro Keith D., Dougherty Matthew J, and Hollier Larry H, eds. Diagnosis and treatment of aortic and peripheral arterial aneurysms. W.B. Saunders, 1999.

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4

Grundmann, Reinhart, ed. Diagnosis, Screening and Treatment of Abdominal, Thoracoabdominal and Thoracic Aortic Aneurysms. InTech, 2011. http://dx.doi.org/10.5772/746.

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5

Astarci, Parla, Laurent de Kerchove, and Gébrine el Khoury. Aortic emergencies. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0061.

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Acute aortic dissections account for the leading and most feared of aortic emergencies. Acute dissections are associated with a dreadful mortality rate; therefore, an accurate diagnosis and immediate treatment are mandatory. The key point of a lifesaving management strategy is the distinction between acute type A dissection, uncomplicated type B dissection, and complicated type B dissection, and those including contained ruptured aorta (severe pleural effusion) and/or malperfusion syndrome (by end-organ ischaemia: paraplegia, intestinal ischaemia, renal insufficiency, limb ischaemia). Type A g
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6

The further history of a case of aneurism of the thoracic aorta of unusually large size attended with localized unilateral swelling. s.n., 1985.

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7

Grundmann, Reinhart, ed. Diagnosis and Treatment of Abdominal and Thoracic Aortic Aneurysms Including the Ascending Aorta and the Aortic Arch. InTech, 2011. http://dx.doi.org/10.5772/996.

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8

de Graaf, Michiel A., Arthur JHA Scholte, Lucia Kroft, and Jeroen J. Bax. Computed tomography angiography and other applications of computed tomography. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0022.

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Patients presenting with acute chest pain constitute a common and important diagnostic challenge. This has increased interest in using computed tomography for non-invasive visualization of coronary artery disease in patients presenting with acute chest pain to the emergency department; particularly the subset of patients who are suspected of having an acute coronary syndrome, but without typical electrocardiographic changes and with normal troponin levels at presentation. As a result of rapid developments in coronary computed tomography angiography technology, high diagnostic accuracies for ex
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9

de Graaf, Michiel A., Arthur JHA Scholte, Lucia Kroft, and Jeroen J. Bax. Computed tomography angiography and other applications of computed tomography. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0022_update_001.

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Patients presenting with acute chest pain constitute a common and important diagnostic challenge. This has increased interest in using computed tomography for non-invasive visualization of coronary artery disease in patients presenting with acute chest pain to the emergency department; particularly the subset of patients who are suspected of having an acute coronary syndrome, but without typical electrocardiographic changes and with normal troponin levels at presentation. As a result of rapid developments in coronary computed tomography angiography technology, high diagnostic accuracies for ex
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10

de Graaf, Michiel A., Arthur JHA Scholte, Lucia Kroft, and Jeroen J. Bax. Computed tomography angiography and other applications of computed tomography. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0022_update_002.

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Patients presenting with acute chest pain constitute a common and important diagnostic challenge. This has increased interest in using computed tomography for non-invasive visualization of coronary artery disease in patients presenting with acute chest pain to the emergency department; particularly the subset of patients who are suspected of having an acute coronary syndrome, but without typical electrocardiographic changes and with normal troponin levels at presentation. As a result of rapid developments in coronary computed tomography angiography technology, high diagnostic accuracies for ex
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11

de Graaf, Michiel A., Arthur JHA Scholte, Lucia Kroft, and Jeroen J. Bax. Computed tomography angiography and other applications of computed tomography. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0022_update_003.

Full text
Abstract:
Patients presenting with acute chest pain constitute a common and important diagnostic challenge. This has increased interest in using computed tomography for non-invasive visualization of coronary artery disease in patients presenting with acute chest pain to the emergency department; particularly the subset of patients who are suspected of having an acute coronary syndrome, but without typical electrocardiographic changes and with normal troponin levels at presentation. As a result of rapid developments in coronary computed tomography angiography technology, high diagnostic accuracies for ex
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12

Reinecke, Holger. Epidemiology and global burden of peripheral arterial disease and aortic aneurysms. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0068.

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Peripheral artery disease (PAD) and aortic aneurysms are common diseases which show an increasing prevalence and incidence. From community-based trials assessing ankle–brachial indices, 2–4% of the general population have been shown to be affected by PAD, which increases up to 15% in those above 70 years of age. About 30–40% of the in-hospital cases with PAD have critical limb ischaemia and suffer from a 1-year mortality of 20–40%. Abdominal aortic aneurysms (AAAs) also show a relatively high prevalence of about 1–2% in the general population as found by large-scale, systematic duplex screenin
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13

Krokidis, Miltiadis, Irfan Ahmed, and Tarun Sabharwal, eds. Challenging Concepts in Interventional Radiology and Endovascular Procedures. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199664382.001.0001.

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Challenging Concepts in Interventional Radiology is a cased-based guide to the most challenging aspects of interventional radiology and endovascular procedures. The 31 Cases have been selected to cover a wide-spectrum of scenarios, from the endovascular repair of thoracic and abdominal aortic aneurysms to the ablation of lung and kidney tumours.
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14

Michel, Jean-Baptiste. Biology of vascular wall dilation and rupture. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755777.003.0016.

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Arterial pathologies, important causes of death and morbidity in humans, are closely related to modifications in the circulatory system during evolution. With increasing intraluminal pressure and arterial bifurcation density, the arterial wall becomes the target of interactions with blood components and outward convection of plasma solutes and particles, including plasma zymogens and leukocyte proteases. Abdominal aortic aneurysms of atherothrombotic origin are characterized by the presence of an intraluminal thrombus (ILT), a major source of proteases, including plasmin, MMP-9, and elastase.
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15

Prapa, Matina, and S. Yen Ho. Arterial wall remodelling in congenital heart disease. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0024.

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The thoracic aorta is the second most common site of aneurysm formation after the abdominal aorta. Thoracic aortic aneurysms (TAAs) often result from medial wall degeneration secondary to genetic aberrations. Over recent decades, unprecedented research in the field of connective tissue disease has led to identification of key molecular pathways involved in TAA formation. Prolonged survival of congenital heart disease patients following successful reparative surgery has also led to increased incidence of TAA in this context with extensive investigations of underlying mechanisms. This chapter su
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16

Thompson, Jonathan P. Anaesthesia for vascular surgery. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0058.

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Vascular surgical patients are at higher risk of cardiovascular morbidity and mortality than other surgical patients, and perioperative care remains challenging. However, vascular surgical practice is changing, with the expanding use of endovascular techniques to treat patients with vascular disease, improvements in medical therapy, and the evolution of evidence-based approaches to preoperative assessment. Preoperative assessment should concentrate on identifying and optimizing potentially correctable medical conditions, in particular cardiovascular disease. Successful outcomes depend on good
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