Books on the topic 'Three-body processes'

Musicians are continually ‘in the making’, tapping into their own creative resources while deriving inspiration from teachers, friends, family members and listeners. Amateur and professional performers alike tend not to follow fixed routes in developing a creative voice; instead, their artistic journeys are personal, often without foreseeable goals. The imperative to assess and reassess one’s musical knowledge, understanding and aspirations is nevertheless a central feature of life as a performer. Musicians in the Making explores the creative development of musicians in both formal and informal learning contexts. It promotes a novel view of creativity, emphasizing its location within creative processes rather than understanding it as an innate quality. It argues that such processes may be learned and refined, and furthermore that collaboration and interaction within group contexts carry significant potential to inform and catalyze creative experiences and outcomes. The book also traces and models the ways in which creative processes evolve over time. Performers, music teachers and researchers will find the rich body of material assembled here engaging and enlightening. The book’s three parts focus in turn on ‘Creative learning in context’, ‘Creative processes’ and ‘Creative dialogue and reflection’. In addition to sixteen extended chapters written by leading experts in the field, the volume includes ten ‘Insights’ by internationally prominent performers, performance teachers and others.

This chapter examines how immigrant women accommodate themselves to the various demands of low-wage, low-status service jobs by engaging in “boundary making,” processes that circumscribe and redefine the performance of “dirty work.” Boundary making refers to material and symbolic processes in which providers of low-wage work impose limitations on its performance while redefining the work as skillful and important. Dirty work is defined as physical labor that involves cleaning and caring for the human body, its products, and its environs. The chapter first provides an overview of certified nursing assistants (CNAs) who provide elder care in the United States before exploring how immigrants working as CNAs make meaning of work that is often construed as dirty work. Using data from fieldwork in three California nursing homes, the chapter shows how CNAs try to bring some measure of dignity to a low-wage, low-status job, and shape their identity formation as workers and immigrants within constraining institutional contexts.

The descriptive poems of the Song (sometimes called waṣfs) are three long texts that punctuate and lend a sense of overall structure to the Song. In these poems, the lover’s body is described as a landscape. This chapter offers a reading of these three texts together as a conceit of process. It argues that the landscape concept relies on an intuition of perspective—of viewing—that orders the audience’s response to the poem’s subject. The descriptive poems build a progressively more developed vision of the lover’s body as a map. As they do so, they model a way of seeing—a lover’s vision—that sees with increasing complexity over time.

Armed conflict is ultimately about the violent confrontation between two or more groups; however, there is a range of behaviors, both violent and nonviolent, pursued by governments and rebel groups while conflict is ongoing that impacts the course and outcomes of that violence. The use of judicial or quasi-judicial institutions during armed conflict is one such behavior. While there is a well-developed body of literature that examines the conditions under which governments engage with the legacies of violence following armed conflict, we know comparatively little about these same institutions used while conflict is ongoing.Similar to the use of transitional justice following armed conflict or post-conflict justice, during-conflict transitional justice (DCJ) refers to “a judicial or quasi-judicial process initiated during an armed conflict that attempts to address wrongdoings that have taken or are taking place as part of that conflict” (according to Loyle and Binningsbø). DCJ includes a variety of institutional forms pursued by both governments and rebel groups such as human rights trials, truth commissions or commissions of inquiry, amnesty offers, reparations, purges, or exiles.As our current understanding of transitional justice has focused exclusively on these processes following a political transition or the termination of an armed conflict, we have a limited understanding of how and why these processes are used during conflict. Extant work has assumed, either implicitly or explicitly, that transitional justice is offered and put in place once violence has ended, but this is not the case. New data on this topic from the During-Conflict Justice dataset by Loyle and Binningsbø suggests that the use of transitional justice during conflict is a widespread and systematic policy across multiple actor groups. In 2017, Loyle and Binningsbø found that DCJ processes were used during over 60% of armed conflicts from 1946 through 2011; and of these processes 10% were put in place by rebel groups (i.e., the group challenging the government rather than the government in power).Three main questions arise from this new finding: Under what conditions are justice processes implemented during conflict, why are these processes put in place, and what is the likely effect of their implementation on the conflict itself? Answering these questions has important implications for understanding patterns of government and rebel behavior while conflict is ongoing and the impacts of those behaviors. Furthermore, this work helps us to broaden our understanding of the use of judicial and quasi-judicial processes to those periods where no power shift has taken place.

In 2011, Ireland seemed to have all the conditions to enable the redesigning of its institutions. The agenda of institutional reform was both imposed upon Irish elites and utilized by them during their campaigns in times of economic crisis and electoral recomposition, but the politicians chose to implement multiple processes of reform separately from each other. Some reforms were conducted primarily by the government, while others were externalized to a device called the Constitutional Convention. The agenda of institutional reforms resulted in three sets of outcomes: one which saw the successful adoption of many small, consensual reforms in the parliament with the support of the parliamentary majority; one where the referendum hurdle proved fatal for (what were initially) consensual reforms driven exclusively by the majority; and one which saw the delegation of the most divisive reforms to an external body, in order to delay the need for a decision.

Drawing on insights from relevance theory, the chapter explores how W.B. Yeats’s late poem ‘Long-legged Fly’ creates an exemplary occasion for reflecting first on cognition and then on the ways in which cognition might be made manifest in poetic language; in particular, here, in a dominant simile that repeats as a refrain through the poem. Processing the three stanzas’ different inferential, sensorimotor, and intertextual effects, we as readers at one and the same time contemplate in each case a body in thought, and we contemplate ourselves thinking. The poem in this sense repeatedly performs how a history-changing reflective moment holds a range of creative energies in dynamic tension. Relevance theory’s ‘loose’ sifting of literal and other meanings, in Deirdre Wilson’s words, allows us to become aware of these two processes unfolding at the same time, and in relation to each other, as is demonstrated in this close reading.

This chapter investigates the first stage of recovery in early modern perceptions, the removal of disease. It shows that three agents were responsible for ousting illness: God, Nature, and the physician. While scholars are familiar with the first and last of these forces, the vital agency of ‘Nature’, the divinely endowed ‘intrinsic agent’ of the body, has been largely overlooked. Personified both as a hardworking housewife and a warrior queen, Nature removed disease through processes that resembled cooking/cleaning and fighting, the ‘concoction’ and ‘expulsion’ of the humours. Particular attention is paid to the complex power–gender dynamic between female Nature and the male doctor: in theory, the physician was ‘Nature’s servant’, but in practice, he often became her commander, a situation which illuminates wider cultural attitudes to womankind. To demonstrate the prevalence of belief in Nature’s healing role, Galenic ideas are compared with those of the Flemish physician J. B. van Helmont.

Created in 1993, the International Criminal Tribunal for the former Yugoslavia (ICTY) has operated longer than any war crimes tribunal in history. It thus offers a singularly important case study of how and why the local impact of an international criminal tribunal (ICT) evolves over time; the circumstances in which international justice can advance the normative, reparative, and other aims of transitional justice; and, more generally, the goals ICTs are either well-suited or unlikely to advance. The book explores the ICTY’s impact in Serbia, whose wartime leader plunged the former Yugoslavia into vicious ethnic conflict, and Bosnia-Herzegovina, which experienced searing atrocities culminating in the Srebrenica genocide, over the life of the Tribunal. It focuses on the Tribunal’s impact in three spheres: victims’ experience of justice; official, elite, and community discourses about wartime atrocities, as well as official gestures of acknowledgment; and domestic accountability processes, including the work of a hybrid court in Bosnia. While highlighting the perspectives of Bosnians and Serbians interviewed by the author, the book incorporates a rich body of interdisciplinary research to deepen their insights.

A commodity chain refers to “a network of labor and production processes whose end result is a finished commodity.” The attention given to this concept has quickly translated into an expanding body of global chains literature. Research into global commodity chains (GCC), and later global value chains (GVC), is an endeavor to explain the social and organizational structure of the global economy and its dynamics by examining the commodity chains of a specific product of service. The GCC approach first emerged in the mid-1980s from world-system research and was reformulated in the early 1990s by development scholars. The development-oriented GCC approach turned the focus of GCC analysis to actor-centered processes in the global economy. One of the initial criticisms facing the GCC approach was its exclusive focus on internal conditions and organizational linkages, lacking systemic attention to the effect of domestic institutions and internal capacity on economic development. Other critics pointed to the narrow scope of GCC research. With the huge expansion in global chains literature in the past decade—not only in volume but also in depth and scope—efforts have been made to elaborate the global chains framework and to render it industry neutral, as partly reflected in the adoption of the term “global value chains.” Three key research themes surround these recent evolutions of global chains literature: GVC governance, “upgrading,” and the social construction of global value chains. Existing literature, however, still has theoretical and methodological gaps to redress.

In Leonardo’s Salvator Mundi and the Collecting of Leonardo in the Stuart Courts the ‘Three Salvateers’—Robert Simon, Martin Kemp and Margaret Dalivalle—give a first-hand account of the discovery of the lost Renaissance masterpiece; from its purchase for $1,175 in a New Orleans auction house in 2005, to the worldwide media spectacle of its sale to a Saudi prince for $450 million in 2017. A behind-the-scenes view of the painstaking processes of identification, consultation, scientific analysis, conservation, and archival research that underpinned the attribution of the painting to Leonardo, the book presents a consideration of the place of the painting in Leonardo’s body of work. Exploring the meaning of the painting in terms of Renaissance theology, it considers the identity of its original patron or intended recipient. Unravelling networks of early modern art dealers and collectors in Europe, it traces the emerging reception of Leonardo during the sixteenth and seventeenth centuries. It was in Enlightenment Britain that the idea of Leonardo as artist–scientist took hold of the public imagination. This book examines the ‘invention’ of Leonardo through the unique prism of the Stuart courts. The documented presence of three paintings of Christ attributed to Leonardo in the vicinity of the seventeenth-century British Royal Collection is both extraordinary and perplexing. Today, Leonardo’s five-hundred-year-old Salvator has not yet disclosed its secret history.

For decades, feminist film analysis has been focused on issues of representation: images of women in film. But what are the feminist implications of the material object underlying that image, the filmstrip itself? What does feminist analysis have to offer in understanding the film image before it enters the realm of representation? In Girl Head: Feminism and Film Materiality, Genevieve Yue explores how gender and sexual difference have been deeply embedded within film materiality. Though the industrial practices she examines are typically hidden from view, they are no less gendered than the images projected onscreen. In rich archival and technical detail, Yue examines three sites of technical film production: the film laboratory, editing practices, and the film archive. Within each site, she locates a common motif, the vanishing female body, which is transformed into material to be used in the making of a film. Yue develops a theory of gender and film materiality through readings of narrative film, early cinema, experimental film, and moving image art. In this original work of feminist media history, Girl Head shows how gender has had a surprising and persistent role in film production processes, well before the image ever appears onscreen.

This chapter follows the process by which a highly detailed account of the human being as bodily being emerges through a series of contemplative practices described in the fifth century by Buddhaghosa in The Path of Purification, a Theravada Buddhist manual. In the first three practices studied, meditation practices are described that disrupt intuitions about the stability of subject and objects, intuitions held to lead to entanglement in suffering. The monk seeking disentanglement comes to be attentive of the way that an apparent sense of isolation of human from environment and of separation of subject from material body is dissolved. The fourth practice addresses the constitution of phenomenology, by analysis of experience through the abhidhamma categories taught by the Buddha. What results is a creative destabilization of any fixed tripartite ontology of subject–body–world, leaving a methodologically sustained practice of treating the human as a phenomenologically dynamic system of analytic categories.

Machiavelli wrote The Prince and the Discourses in exile, after three weeks being imprisoned and tortured because he was falsely suspected of being involved in an assassination attempt against the Medici. Reading those works, and particularly the former, through the light cast by torture, casts a new light on Machiavelli’s argument about new regimes and on the use of torture in the US foreign policy in the twenty-first century. Drawing on Elaine Scarry’s The Body in Pain and Hannah Arendt’s Origins of Totalitarianism, the chapter argues that torture is designed as an ideological process, a way to disrupt potential political communities and to replace them with audiences for the “fiction of power” and authority that new regimes create through physical torture and the displacement of populations.

This study uses the analysis of visual metaphor in 35 graphic illness narratives—book-length stories about disease in the comics medium—in order to re-examine embodiment in traditional Conceptual Metaphor Theory (CMT) and propose the more nuanced notion of “dynamic embodiment.” Building on recent strands of research within CMT, and drawing on relevant concepts and findings from other disciplines, including psychology, phenomenology, social semiotics, and media theory, the book develops the argument that the experience of one’s own body is constantly adjusting to changes in one’s individual state of health, sociocultural practices, and the activities in which one is engaged at any given moment, including the modes and media that are being used to communicate. This leads to a more fluid and variable relationship between physicality and metaphor use than many CMT scholars assume. For example, representing the experience of cancer through the graphic illness narrative genre draws attention to the unfathomable processes going on beneath the body’s visible surface, particularly now that digital imaging technologies play such a central role in the diagnosis and treatment of the disease. This may lead to a reversal of conventional conceptualizations of knowing and understanding in terms of seeing, so that vision itself becomes the target of metaphorical representations. A novel classification system of visual metaphor, based on a three-way distinction between pictorial, spatial, and stylistic metaphors, is also proposed.

David W. Kling explores the exegetical foundations of Jonthan Edwards’ understanding of conversion. Given the importance of revivalism in Edwards’ career, one cannot deny the preeminent place of conversion in his thought and preaching. Yet fundamental to that doctrine was Scripture’s teaching on the nature of conversion. Kling probes this topic by treating the role of the Bible in Edwards’ own conversion, distinct as it was from the reigning model in his tradition; by considering the place of conversion in Edwards’ discussion of the revivals; and by examining the intersection of Scripture and conversion in three representative awakening sermons. In Edwards’ view, the Bible taught that conversion is real, that it transforms not only the soul but also the body, and that it involves both a “first conversion” and an ongoing process.

Through close readings, Shelleyan Reimaginings and Influence: New Relations seeks to bring out the imaginative and formal brilliance of Percy Bysshe Shelley’s writing as it explores his involvement in processes of dialogue and influence. Shelley is among the major Romantic poetic exponents and theorists of influence because of his passionately intelligent commitment to the onward dissemination of ideas and feelings and to the unpredictable ways in which poets position themselves and are culturally positioned between past and future. The book has a tripartite structure. The first three chapters seek to illuminate his response to representative texts, figures, and themes that constitute the triple pillars of his cultural inheritance: the classical world (Plato); Renaissance poetry (Spenser and Milton); and Christianity—in particular, the concept of deity and the Bible. The second and major section of the book, from Chapters 4 to 12, explores Shelley’s relations and affinities with, as well as differences from, his immediate predecessors and contemporaries: Hazlitt and Lamb; Wordsworth; Coleridge; Southey; Byron; Keats (including the influence of Dante on Shelley’s elegy for his fellow Romantic); and the great painter J. M. W. Turner, with whom he is often linked. The third section considers Shelley’s reception by later nineteenth-century writers, figures influenced by and responding to Shelley: the figures chosen are Beddoes, Hemans, Landon, Tennyson, and Swinburne. A Coda discusses the body of critical work on Shelley produced by A. C. Bradley, a figure who stands at the threshold of twentieth-century thinking about Shelley.

In a world that is responding to ever-changing ideas and expressions of gender, this book adds new insights on transgender children and the parents who support them. Drawing on in-depth interview data with more than fifty parents, the book examines parents’ shifting understandings of their children’s gender and how they come to help their children make sense of their identities and their bodies. Throughout these processes, the book shows that parents’ meaning-making and decision-making often challenge LGBT rights discourses, as well as queer political tenets, in unexpected ways. These dynamics surface in three key areas: (1) gender and sexuality, (2) the gender binary, and (3) the body. Throughout parents’ understandings, gender identity and sexual orientation do not always present as radically separate aspects of the self, but are more fluid and open to reconsideration, given new cultural contexts, opportunities, and phases of the life course. And despite increasing cultural visibility around nonbinary identities, “gender-expansive” child-rearing often looks, fundamentally, very binary and gender-stereotypical, per the children’s own assertions and expressions. Lastly, parents often utilize highly medicalized understandings of transgender embodiment, which nevertheless resonate with some children’s sensibilities. Altogether, these families depart from conventional understandings of gender, sexuality, and the binary, but in ways that prioritize child-centered shifts, meanings, and parenting models, not necessarily LGBTQ politics or paradigms. This marks new ground for understanding the mechanisms and parameters of the (trans)gender change afoot.

This chapter details how the mediated NFL draft emerged out of a set of contingencies produced by shifts in sport media industries during the early 1980s. The event grew in popularity by presenting the thorough, extended, and systematic assessment of NFL prospects as entertaining. But this fun has a profound political edge. By framing NFL prospects as transparent, knowable docile bodies, the discourses of the draft present them explicitly as commodities to be compared with each other. Thus positioned, prospects, the vast majority of prospects of whom are black, circulate in ways that revive looking practices that connect the male body, race, commerce, and pleasure. To unpack this process, the chapter proceeds in three parts. The first details how the draft came to be a televised spectacle. This is followed by a discussion of the process by which prospects are presented as docile bodies and explicitly imagined as useful, malleable commodities. I then consider how the dynamics of this market mobilize expressions of erotic desire for commodified black male bodies.

Investment treaties grant special international protection to foreign investors, and give them a means to enforce those rights against States in which they have invested. This book examines systematically the law of international investment treaties. Although the precise provisions of investment treaties are not uniform, virtually all investment treaties address the same issues. This book examines those issues in detail, including the scope of application, conditions for the entry of foreign investment, and general standards of treatment of foreign investments. Investment treaty law has continued to evolve rapidly and dramatically since publication of the second edition of this work in 2015. The field has seen considerable growth in the number and scope of investment treaties, now estimated at 3300, and investor-state arbitrations cases, which reached over 1000 in 2020. Beyond growth, the field has also experienced significant changes and reforms. In 2018, eleven Pacific Basin Countries, despite the withdrawal of the United States, forged ahead to conclude the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CPTTP), a potentially far reaching regional trade and investment agreement. The next year, the three north American nations replaced the North American Free Trade Agreement (NAFTA) with the United States-Mexico-Canada Agreement (USMCA). And in 2020, European Union member states terminated over 100 intra-EU BITs, leaving intra-EU investors to rely on EU law and legal processes alone for protection from unfavourable government acts. This edition incorporates a consideration of all of these and other reforms into its analysis of the body of law created by investment treaties since World War II.

Modernist Objects is a unique mix of cultural studies, literature, and visual arts applied to the discrete materiality of objects. It places objects, how they emerge or withdraw, how they fashion us, and what status they hold, at the heart of what constitutes modernism. Three processes are consistently to be observed in modernist object experiments: objecting to realism, fashioning the human, and performing the ornamental. The cumbersome bourgeois semiotics of material possessions was itself taken on by writers as diverse as Beckett or Djuna Barnes as a material to be chipped away at, given new life or hollowed out. Writers and creators embraced the object in a way that culminated in such intimate extensions of the mind and body as constructivist clothing, literary magazines, musical instruments, and restorative sculptures. The most skin-deep artifice is shown here to have epoch-changing potentialities. Can a lost brooch define the feminine through an aesthetics of absence? Can the ever-accelerating succession of hats on the head of a lonely alien in Paris,or of manufactured appliances on the dress of a German baroness, loosen the maddening grip of consumer society? Can the bourgeoisie be placed in a position to camp gender (Boscagli) through the use of Japanese lacquer on the outer surfaces of a recliner? This book is characterized by attentiveness to works hitherto considered as minor alongside canonical ones, a careful reclaiming of women’s writing and fine art, and a methodological habitof extending transnational probes outside the realm of the English language.

This chapter discusses the collection of objects, in clay and stone, from various pastoral Saharan sites whose original core area lay between Libya (Tadrart Acacus) and Algeria (Tassili- n-Ajjer). The chapter starts from the general theme of the relationship between the figurines and the subjects they represent, and the difference between two-dimensional and three-dimensional representation. It goes on to discuss the manufacturing process of the clay specimens (dating from between 7000 and 4000 years ago) and the significance of the changes introduced by the Neolithic. Most of the items studied fall into the category of zoomorphic figurines, with only two anthropomorphic examples, and find in the depiction of cattle their most striking subject. These representations possess an evident symbolic content which must be framed within the pastoral ideology of the Saharan Neolithic. In the anthropomorphic figurines the representation of the human body also plays the role of recapturing the sense of wholeness.

This book addresses whether and how emissions trading schemes to mitigate climate change are subject to the network of treaties comprising the international trade and investment regime, collectively referred to as international economic law. Chapter 1 introduces the broad structure and content of the book, which is divided into three principal parts. Part I, comprising Chapters 2 and 3, sets out the approach of the book, insofar as it involves initial process of treaty interpretation to determine the scope and content of relevant aspects of international economic law (including any relevant interaction with the international climate regime), followed by a subsequent process of applying the resulting interpretations to carbon units and the aspects of emissions trading schemes that affect their trade and investment in ways which attract the scrutiny of international economic law. Part II, covering Chapters 4–7, then seeks to ascertain whether carbon units are subject to international economic law by evaluating whether they qualify as ‘goods’/‘products’, ‘services’, ‘financial services’, and ‘investments’. Having determined that carbon units are, to varying extents, subject to international economic law, Part III (comprising Chapters 8 and 9) assesses the consistency of emissions trading schemes and their rules affecting carbon units with that body of law.

William James's 1884 theory of emotion is perhaps the most well known of all his psychological ideas, particularly as it forms a key historical landmark in the history of the concept. His notion of “religious emotion” is perhaps one of the most important in shaping the subject in the twentieth century. The complex history of James's theory of emotion begins when he and the Danish physician Karl Georg Lange established a post-Darwinian, organic theory of emotions, in what became known as the James-Lange theory. This view of emotion went against the grain of contemporary theories of emotion in the new psychology, particularly that put forward by Wilhelm Wundt, who argued for a theory of “apperception”—the process by which a state of mind (the affect or emotion) produces bodily effects. This article examines James's theory of emotion and religious emotion, focusing on his views about mind and body. It also discusses three theories of emotion, namely, organic theory, cognitive theory, and social theory. Finally, it considers pluralism, mystical emotions, metaphysical emotions, and the reflex circuit of emotion.

Bones are multifunctional passive organs of movement that supports soft tissue and directly attached muscles. They also protect internal organs and are a reserve of calcium, phosphorus and magnesium. Each bone is covered with periosteum, and the adjacent bone surfaces are covered by articular cartilage. Histologically, the bone is an organ composed of many different tissues. The main component is bone tissue (cortical and spongy) composed of a set of bone cells and intercellular substance (mineral and organic), it also contains fat, hematopoietic (bone marrow) and cartilaginous tissue. Bones are a tissue that even in adult life retains the ability to change shape and structure depending on changes in their mechanical and hormonal environment, as well as self-renewal and repair capabilities. This process is called bone turnover. The basic processes of bone turnover are: • bone modeling (incessantly changes in bone shape during individual growth) following resorption and tissue formation at various locations (e.g. bone marrow formation) to increase mass and skeletal morphology. This process occurs in the bones of growing individuals and stops after reaching puberty • bone remodeling (processes involve in maintaining bone tissue by resorbing and replacing old bone tissue with new tissue in the same place, e.g. repairing micro fractures). It is a process involving the removal and internal remodeling of existing bone and is responsible for maintaining tissue mass and architecture of mature bones. Bone turnover is regulated by two types of transformation: • osteoclastogenesis, i.e. formation of cells responsible for bone resorption • osteoblastogenesis, i.e. formation of cells responsible for bone formation (bone matrix synthesis and mineralization) Bone maturity can be defined as the completion of basic structural development and mineralization leading to maximum mass and optimal mechanical strength. The highest rate of increase in pig bone mass is observed in the first twelve weeks after birth. This period of growth is considered crucial for optimizing the growth of the skeleton of pigs, because the degree of bone mineralization in later life stages (adulthood) depends largely on the amount of bone minerals accumulated in the early stages of their growth. The development of the technique allows to determine the condition of the skeletal system (or individual bones) in living animals by methods used in human medicine, or after their slaughter. For in vivo determination of bone properties, Abstract 10 double energy X-ray absorptiometry or computed tomography scanning techniques are used. Both methods allow the quantification of mineral content and bone mineral density. The most important property from a practical point of view is the bone’s bending strength, which is directly determined by the maximum bending force. The most important factors affecting bone strength are: • age (growth period), • gender and the associated hormonal balance, • genotype and modification of genes responsible for bone growth • chemical composition of the body (protein and fat content, and the proportion between these components), • physical activity and related bone load, • nutritional factors: – protein intake influencing synthesis of organic matrix of bone, – content of minerals in the feed (CA, P, Zn, Ca/P, Mg, Mn, Na, Cl, K, Cu ratio) influencing synthesis of the inorganic matrix of bone, – mineral/protein ratio in the diet (Ca/protein, P/protein, Zn/protein) – feed energy concentration, – energy source (content of saturated fatty acids - SFA, content of polyun saturated fatty acids - PUFA, in particular ALA, EPA, DPA, DHA), – feed additives, in particular: enzymes (e.g. phytase releasing of minerals bounded in phytin complexes), probiotics and prebiotics (e.g. inulin improving the function of the digestive tract by increasing absorption of nutrients), – vitamin content that regulate metabolism and biochemical changes occurring in bone tissue (e.g. vitamin D3, B6, C and K). This study was based on the results of research experiments from available literature, and studies on growing pigs carried out at the Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences. The tests were performed in total on 300 pigs of Duroc, Pietrain, Puławska breeds, line 990 and hybrids (Great White × Duroc, Great White × Landrace), PIC pigs, slaughtered at different body weight during the growth period from 15 to 130 kg. Bones for biomechanical tests were collected after slaughter from each pig. Their length, mass and volume were determined. Based on these measurements, the specific weight (density, g/cm3) was calculated. Then each bone was cut in the middle of the shaft and the outer and inner diameters were measured both horizontally and vertically. Based on these measurements, the following indicators were calculated: • cortical thickness, • cortical surface, • cortical index. Abstract 11 Bone strength was tested by a three-point bending test. The obtained data enabled the determination of: • bending force (the magnitude of the maximum force at which disintegration and disruption of bone structure occurs), • strength (the amount of maximum force needed to break/crack of bone), • stiffness (quotient of the force acting on the bone and the amount of displacement occurring under the influence of this force). Investigation of changes in physical and biomechanical features of bones during growth was performed on pigs of the synthetic 990 line growing from 15 to 130 kg body weight. The animals were slaughtered successively at a body weight of 15, 30, 40, 50, 70, 90, 110 and 130 kg. After slaughter, the following bones were separated from the right half-carcass: humerus, 3rd and 4th metatarsal bone, femur, tibia and fibula as well as 3rd and 4th metatarsal bone. The features of bones were determined using methods described in the methodology. Describing bone growth with the Gompertz equation, it was found that the earliest slowdown of bone growth curve was observed for metacarpal and metatarsal bones. This means that these bones matured the most quickly. The established data also indicate that the rib is the slowest maturing bone. The femur, humerus, tibia and fibula were between the values of these features for the metatarsal, metacarpal and rib bones. The rate of increase in bone mass and length differed significantly between the examined bones, but in all cases it was lower (coefficient b <1) than the growth rate of the whole body of the animal. The fastest growth rate was estimated for the rib mass (coefficient b = 0.93). Among the long bones, the humerus (coefficient b = 0.81) was characterized by the fastest rate of weight gain, however femur the smallest (coefficient b = 0.71). The lowest rate of bone mass increase was observed in the foot bones, with the metacarpal bones having a slightly higher value of coefficient b than the metatarsal bones (0.67 vs 0.62). The third bone had a lower growth rate than the fourth bone, regardless of whether they were metatarsal or metacarpal. The value of the bending force increased as the animals grew. Regardless of the growth point tested, the highest values were observed for the humerus, tibia and femur, smaller for the metatarsal and metacarpal bone, and the lowest for the fibula and rib. The rate of change in the value of this indicator increased at a similar rate as the body weight changes of the animals in the case of the fibula and the fourth metacarpal bone (b value = 0.98), and more slowly in the case of the metatarsal bone, the third metacarpal bone, and the tibia bone (values of the b ratio 0.81–0.85), and the slowest femur, humerus and rib (value of b = 0.60–0.66). Bone stiffness increased as animals grew. Regardless of the growth point tested, the highest values were observed for the humerus, tibia and femur, smaller for the metatarsal and metacarpal bone, and the lowest for the fibula and rib. Abstract 12 The rate of change in the value of this indicator changed at a faster rate than the increase in weight of pigs in the case of metacarpal and metatarsal bones (coefficient b = 1.01–1.22), slightly slower in the case of fibula (coefficient b = 0.92), definitely slower in the case of the tibia (b = 0.73), ribs (b = 0.66), femur (b = 0.59) and humerus (b = 0.50). Bone strength increased as animals grew. Regardless of the growth point tested, bone strength was as follows femur > tibia > humerus > 4 metacarpal> 3 metacarpal> 3 metatarsal > 4 metatarsal > rib> fibula. The rate of increase in strength of all examined bones was greater than the rate of weight gain of pigs (value of the coefficient b = 2.04–3.26). As the animals grew, the bone density increased. However, the growth rate of this indicator for the majority of bones was slower than the rate of weight gain (the value of the coefficient b ranged from 0.37 – humerus to 0.84 – fibula). The exception was the rib, whose density increased at a similar pace increasing the body weight of animals (value of the coefficient b = 0.97). The study on the influence of the breed and the feeding intensity on bone characteristics (physical and biomechanical) was performed on pigs of the breeds Duroc, Pietrain, and synthetic 990 during a growth period of 15 to 70 kg body weight. Animals were fed ad libitum or dosed system. After slaughter at a body weight of 70 kg, three bones were taken from the right half-carcass: femur, three metatarsal, and three metacarpal and subjected to the determinations described in the methodology. The weight of bones of animals fed aa libitum was significantly lower than in pigs fed restrictively All bones of Duroc breed were significantly heavier and longer than Pietrain and 990 pig bones. The average values of bending force for the examined bones took the following order: III metatarsal bone (63.5 kg) <III metacarpal bone (77.9 kg) <femur (271.5 kg). The feeding system and breed of pigs had no significant effect on the value of this indicator. The average values of the bones strength took the following order: III metatarsal bone (92.6 kg) <III metacarpal (107.2 kg) <femur (353.1 kg). Feeding intensity and breed of animals had no significant effect on the value of this feature of the bones tested. The average bone density took the following order: femur (1.23 g/cm3) <III metatarsal bone (1.26 g/cm3) <III metacarpal bone (1.34 g / cm3). The density of bones of animals fed aa libitum was higher (P<0.01) than in animals fed with a dosing system. The density of examined bones within the breeds took the following order: Pietrain race> line 990> Duroc race. The differences between the “extreme” breeds were: 7.2% (III metatarsal bone), 8.3% (III metacarpal bone), 8.4% (femur). Abstract 13 The average bone stiffness took the following order: III metatarsal bone (35.1 kg/mm) <III metacarpus (41.5 kg/mm) <femur (60.5 kg/mm). This indicator did not differ between the groups of pigs fed at different intensity, except for the metacarpal bone, which was more stiffer in pigs fed aa libitum (P<0.05). The femur of animals fed ad libitum showed a tendency (P<0.09) to be more stiffer and a force of 4.5 kg required for its displacement by 1 mm. Breed differences in stiffness were found for the femur (P <0.05) and III metacarpal bone (P <0.05). For femur, the highest value of this indicator was found in Pietrain pigs (64.5 kg/mm), lower in pigs of 990 line (61.6 kg/mm) and the lowest in Duroc pigs (55.3 kg/mm). In turn, the 3rd metacarpal bone of Duroc and Pietrain pigs had similar stiffness (39.0 and 40.0 kg/mm respectively) and was smaller than that of line 990 pigs (45.4 kg/mm). The thickness of the cortical bone layer took the following order: III metatarsal bone (2.25 mm) <III metacarpal bone (2.41 mm) <femur (5.12 mm). The feeding system did not affect this indicator. Breed differences (P <0.05) for this trait were found only for the femur bone: Duroc (5.42 mm)> line 990 (5.13 mm)> Pietrain (4.81 mm). The cross sectional area of the examined bones was arranged in the following order: III metatarsal bone (84 mm2) <III metacarpal bone (90 mm2) <femur (286 mm2). The feeding system had no effect on the value of this bone trait, with the exception of the femur, which in animals fed the dosing system was 4.7% higher (P<0.05) than in pigs fed ad libitum. Breed differences (P<0.01) in the coross sectional area were found only in femur and III metatarsal bone. The value of this indicator was the highest in Duroc pigs, lower in 990 animals and the lowest in Pietrain pigs. The cortical index of individual bones was in the following order: III metatarsal bone (31.86) <III metacarpal bone (33.86) <femur (44.75). However, its value did not significantly depend on the intensity of feeding or the breed of pigs.

The European Parliament (EP) has grown from a “talking shop” to a fully-fledged legislative body in the European Union (EU)’s bicameral system. This process of communautarization and parliamentarization has generated considerable attention in the academic field. Furthermore, in today’s political environment—characterized by the polarization of public opinion, Brexit, the lingering effects of the Eurozone crisis, and the steady rise of Euroskeptical and radical forces throughout Europe—the role of the European Parliament (EP) is perhaps more critical to understand and assess than ever before. An overarching question in the literature is how “normal” the EP has become. Drawing on David Easton’s political systems approach, we examine this condition in three sub-literatures: the literature on inputs (demands), the literature on withinputs (inter-institutional processing of inputs), and the literature on outputs (EP decisions and actions, and the impact thereof). Building on this literature and contributing to the ongoing debate on the nature and significance of the EP, we propose to conceptualize the EP as “a normal parliament in a polity of a different kind.” This paradoxical conceptualization reflects abundant insights that, despite the EP gaining comprehensive lawmaking powers that are quite unparalleled in the world of international politics, its functioning and significance remain profoundly, distinctly, and probably durably, shaped by the multilevel nature of EU politics.

This is an account of John Ashbery’s career in which, as he puts it in ‘Grand Galop’, the ‘minor eras / Take on an importance all out of proportion to the story’.1 The ‘minority’ of any part of any story is, of course, a relational status always open to dispute, but in the available narratives of Ashbery’s life and work his personal and textual engagements with contemporaneous English poets have, up to this point, occupied a certifiably marginal position. This is unsurprising. When compared with the most ambitious, compelling narratives of Ashbery’s place within literary history—portraying him as a late Romantic, a Francophile avant-gardist, or a coterie poet of the New York School, among many other possible identities—concentrating on his English connections might seem a limited perspective from which to view his work. Yet because the idea of ‘minority’ was a central preoccupation for Ashbery throughout his career, it is apt to discover that many of the important, enduring points of interest which occupied his poetry and poetics—the relation of the margin to the centre, the ways in which art represents the historical moment of its composition, the processes by which canons are formed, the methods through which aesthetic ‘strength’ and ‘weakness’ are determined, the connection between national identities and traditions and individual poetic expression—are foregrounded and illuminated when raised within such a ‘minor’ context. The limitation of scope in this study—which attends to Ashbery’s relationships with W. H. Auden, F. T. Prince, Lee Harwood and Mark Ford—allows for a localized, concentrated sample of his writing to be attended to, and obliquely to substantiate or complicate our understanding of more general themes or practices in his oeuvre. Ashbery’s body of work is broad and varied enough to justify its fragmentation into specific sub-categories, which in combination will allow for a larger, more comprehensive and more complex picture of this inexhaustible poet to be presented. This book hopes to make three central contributions to that broader picture: to demonstrate the significance of Anglo-American contexts to Ashbery’s work, to illustrate his importance ...

This book discusses Aristotle’s biological views about character and the importance of what he calls “natural character traits” for the development of moral virtue as presented in his ethical treatises. It provides a new, comprehensive account of the physiological underpinnings of moral development and thereby shows, first, that Aristotle’s ethical theories do not exhaust his views about character, as has traditionally been assumed, and, second, that his treatment of natural character in the biological treatises provides the conceptual and ideological foundation for his views about habituation as developed in his ethics. This manuscript thus takes seriously Aristotle’s claim—often ignored—that nature is one of the factors through which men become “good and capable of fine deeds.” Part I (“The Physiology and Science of Natural Character”) analyzes, in three chapters, Aristotle’s notion of natural character as it is developed in the biological treatises and its role in moral development, especially as it affects women and certain “barbarians”—groups who are typically left out of accounts of Aristotle’s ethics. I also discuss its relevance for our understanding of physiognomical ideas in Aristotle. Part II (“The Physiology of Moral Development”) explores the psychophysical changes in body and soul that one is required to undergo in the process of acquiring moral virtues. It includes a discussion of Aristotle’s eugenic views, his identification of habituation as a form of human perfection, and his claims about the moral deficiencies of women that link them to his beliefs about their biological imperfections.

Physician Certification and Lab Accreditation in Nuclear Cardiology are two key cornerstones of the Quality Program of this medical field. The ability and privilege to handle Isotopes for medical use is regulated by NRC with federal laws on training and experience (10CFR 35) incorporated into clinical training guidelines. Core Cardiology Training Symposium (COCATS) and documents sponsored (and updated) by the American College of Cardiology (ACC) specify the clinical training necessary to independently practice nuclear cardiology. Certification Board of Nuclear Cardiology (CBNC) collects appropriate prerequisite statements of training that match guidelines and administers a well- constructed examination leading to physician certification in recognition of meeting national standards to practice Nuclear Cardiology. Policies and procedures of NRC/COCATS/CBNC are reviewed in this chapter and near term challenges to evolving physician certification in a complex healthcare system are explored. Lab Accreditation is a quality process that goes beyond physicians to assess equipment, staff, policies and procedures, image quality, and reporting. Lab accreditation by one of three recognized accrediting bodies is now mandated for reimbursement of advanced imaging in Medicare program. Intersociety Accreditation Commission (IAC, Nuclear/PET division) is a recognized body for lab accreditation and has placed special emphasis on clinical reporting/outcomes and meaningful quality improvement activities. IAC Nuclear cardiology Standards are reviewed as opportunities to externally be recognized for meeting quality standards within a protected peer review climate. As with certification, near term challenges exist for evolving lab accreditation and these are explored as well in this chapter.

It is obvious that the process of developing cancer—oncogenesis—is a multistep process. We know that smoking, obesity, and a family history are strong independent predictors of developing malignancy; yet, in clinics, we often see that some heavy smokers live into their nineties and that some people with close relatives affected by cancer spend many years worrying about a disease that, in the end, they never contract. For many centuries scientists have struggled to understand the process that make cancer cells different from normal cells. There were those in ancient times who believed that tumours were attributable to acts of the gods. Hippocrates suggested that cancer resulted from an imbalance between the black humour that came from the spleen, and the other three humours: blood, phlegm, and bile. It is only in the last 100 years that biologists have been able to characterize some of the pathways that lead to the uncontrolled replication seen in cancer, and subsequently examine exactly how these pathways evolve. The rampant nature by which cancer invades local and distant tissues, as well its apparent ability to spread between related individuals led some, such as Peyton Rous in 1910, to suggest that cancer was an infectious condition. He was awarded a Nobel Prize in 1966 for the 50 years of work into investigating a link between sarcoma in chickens and a retrovirus that became known as Rous sarcoma virus. He had shown how retroviruses are able to integrate sequences of DNA coding for errors in cellular replication control (oncogenes) by introducing into the human cell viral RNA together with a reverse transcriptase. Viruses are now implicated in many cancers, and in countries where viruses such as HIV and EBV are endemic, the high incidence of malignancies such as Kaposi’s sarcoma and Burkitt’s lymphoma is likely to be directly related. There are several families of viruses associated with cancer, broadly classed into DNA viruses, which mutate human genes using their own DNA, and retroviruses, like Rous sarcoma virus, which insert viral RNA into the cell, where it is then transcribed into genes. This link with viruses has not only led to an understanding that cancer originates from genetic mutations, but has also become a key focus in the design of new anticancer therapies. Traditional chemotherapies either alter DNA structure (as with cisplatin) or inhibit production of its component parts (as with 5-fluorouracil.) These broad-spectrum agents have many and varied side effects, largely due to their non-specific activity on replicating DNA throughout the body, not just in tumour cells. New vaccine therapies utilizing gene-coding viruses aim to restore deficient biological pathways or inhibit mutated ones specific to tumour cells. The hope is that these gene therapies will be effective and easily tolerated by patients, but development is currently progressing with caution. In a trial in France of ten children suffering from X-linked severe combined immunodeficiency and who were injected with a vector that coded for the gene product they lacked, two of the children subsequently died from leukaemia. Further analysis confirmed that the DNA from the viral vector had become integrated into an existing, but normally inactive, proto-oncogene, LM02, triggering its conversion into an active oncogene, and the development of life-threatening malignancy. To understand how a tiny change in genetic structure could lead to such tragic consequences, we need to understand the molecular biology of the cell and, in particular, to pay attention to the pathways of growth regulation that are necessary in all mammalian cell populations. Errors in six key regulatory pathways are known as the ‘hallmarks of cancer’ and will be discussed in the rest of this chapter.