Relevant bibliographies by topics / Thrombectomy

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Thrombectomy'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 June 2025

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Journal articles on the topic "Thrombectomy"

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Dumont, T. M., M. Mokin, G. C. Sorkin, E. I. Levy, and A. H. Siddiqui. "Aspiration thrombectomy in concert with stent thrombectomy." Case Reports 2013, jul12 1 (2013): bcr2012010624. http://dx.doi.org/10.1136/bcr-2012-010624.

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Dumont, Travis M., Maxim Mokin, Grant C. Sorkin, Elad I. Levy, and Adnan H. Siddiqui. "Aspiration thrombectomy in concert with stent thrombectomy." Journal of NeuroInterventional Surgery 6, no. 4 (2013): e26-e26. http://dx.doi.org/10.1136/neurintsurg-2012-010624.rep.

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Evans, Matthew C., and Anbukarasi Maran. "Aspiration Thrombectomy." Interventional Cardiology Clinics 10, no. 3 (2021): 317–22. http://dx.doi.org/10.1016/j.iccl.2021.04.001.

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Lauzier, David C., Maria M. Galardi, Kristin P. Guilliams, et al. "Pediatric Thrombectomy." Stroke 52, no. 4 (2021): 1511–19. http://dx.doi.org/10.1161/strokeaha.120.032268.

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Endovascular thrombectomy has played a major role in advancing adult stroke care and may serve a similar role in pediatric stroke care. However, there is a need to develop better evidence and infrastructure for pediatric stroke care. In this work, we review 2 experienced pediatric endovascular thrombectomy programs and examine key design features in both care environments, including a formalized protocol and workflow, integration with an adult endovascular thrombectomy workflow, simplification and automation of workflow steps, pediatric adaptations of stroke imaging, advocacy of pediatric stroke care, and collaboration between providers, among others. These essential features transcend any single hospital environment and may provide an important foundation for other pediatric centers that aim to enhance the care of children with stroke.
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Ojiro, Masataka. "Venous Thrombectomy." Japanese Journal of Phlebology 11, no. 3 (2000): 271–76. http://dx.doi.org/10.7134/phlebol.11-3-271.

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Mullen, Michael T., and Seemant Chaturvedi. "Endovascular thrombectomy." Neurology 88, no. 22 (2017): 2074–75. http://dx.doi.org/10.1212/wnl.0000000000003993.

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Nicolaides, A., J. Fareed, A. K. Kakkar, et al. "Surgical Thrombectomy." Clinical and Applied Thrombosis/Hemostasis 19, no. 2 (2013): 205–6. http://dx.doi.org/10.1177/1076029612474840q.

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Wu, Yuefei, Congguo Yin, Jianhong Yang, Lin Jiang, Mark W. Parsons, and Longting Lin. "Endovascular Thrombectomy." Stroke 49, no. 11 (2018): 2783–85. http://dx.doi.org/10.1161/strokeaha.118.022919.

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Balan, Prakash, and H. Vernon Anderson. "Aspiration Thrombectomy." Journal of the American College of Cardiology 62, no. 16 (2013): 1419–20. http://dx.doi.org/10.1016/j.jacc.2013.03.069.

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Hung, Chi-Sheng, Mao-Shin Lin, Ying-Hsien Chen, Ching-Chang Huang, Hung-Yuan Li, and Hsien-Li Kao. "Aspiration Thrombectomy." Journal of the American College of Cardiology 65, no. 9 (2015): 960–61. http://dx.doi.org/10.1016/j.jacc.2014.10.077.

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Dissertations / Theses on the topic "Thrombectomy"

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Machi, Paolo. "Evaluation expérimentale des propriétés mécaniques et de l'efficacité d'enlèvement des thrombus des stent retrievers." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT263/document.

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Un certain nombre d'essais cliniques contrôlés, randomisés et publiés récemment en littérature a démontré que la thrombectomie mécanique, offerte aux patients présentant un AVC ischémique aigu, est liée à une meilleure évolution clinique en comparaison au traitement standard de fibrinolyse intraveineuse. Les stents retriever ont été reconnus dans ces essais comme les dispositifs les plus efficaces pour la thrombectomie intracrânienne. Actuellement, toutes les industries produisant des dispositifs neuro-interventionnels lancent sur le marché un nombre croissant de stents retriever. Chaque nouveau dispositif proposé est censé avoir une particularité permettant de meilleures performances par rapport aux dispositifs déjà disponibles sur le marché. Néanmoins, aucune étude clinique n’a démontré, jusqu'à présent, la supériorité en termes de résultats anatomiques et cliniques d'un stent retriever donné. En outre, le mécanisme d'interaction entre les stents retriever et le thrombus n'a pas été évalué jusqu'ici de façon exhaustive. Dans la présente étude, nous avons analysé expérimentalement les performances de tous les stents retriever disponibles sur le marché français jusqu'à juin 2015. Le but de cette étude était d'identifier toutes les caractéristiques des dispositifs fonctionnels à la capture du thrombus. Chaque dispositif a été évalué par des tests mécaniques et fonctionnels : les tests mécaniques ont été effectués afin d'étudier la force radiale des dispositifs. L'objectif était d'évaluer la force radiale exercée par le stent dans deux conditions spécifiques : lors du déploiement et pendant le retrait.Les tests fonctionnels ont visé à évaluer visuellement la capacité du stent à rester en apposition sur la paroi des vaisseaux et à maintenir le thrombus à l'intérieur de ses mailles au cours du retrait. Nous avons évalué l'interaction des dispositifs avec thrombus de taille et de caractéristiques différentes que nous avons générées en utilisant du sang humain afin d'obtenir deux types de caillot : un souple « de type rouge » composé par tous les éléments du sang et un dur « de type blanc» qui a été principalement composé de plasma riche en plaquettes. Ces essais ont été effectués en utilisant un modèle vasculaire rigide reproduisant la circulation cérébrale antérieure. Deux neuro-interventionnels ayant une expérience dans les procédures de thrombectomie ont effectué les tests fonctionnels. Chaque expérience a été filmée et deux auteurs par la suite ont effectué une analyse visuelle des résultats.Les essais mécaniques ont montré un comportement différent en termes de variation de pression radiale au cours du retrait pour chaque stent. Une pression radiale constante pendant le retrait est liée à une cohésion constante sur la paroi artérielle pendant le retrait, avec un taux plus important de retrait du caillot. Tous les stents retriever glissent sur le caillot blanc de grande taille (diamètre&gt;6 mm) ayant un très bas taux d’efficacité en termes de retrait<br>A number of randomized controlled trials recently appeared in literature demonstrated that early mechanical thrombectomy offered to patients presenting with acute ischemic stroke is related to improved functional outcome in comparison to standard care intravenous fibrinolysis. Stent retrievers have been recognized in these trials as the most effective devices for intracranial thrombectomy. Currently, all industries producing neuro-interventional devices are launching into the market an increasing number of stent-based retriever tools. Each new device proposed for clinical use is supposed to have peculiar features allowing better performances in comparison to devices already available for clinical practice. Nevertheless, none clinical study has demonstrated so far the superiority, in terms of anatomical and clinical results, of a given stent retriever device. Furthermore, the mechanism of interaction between stent retrievers and thrombi has not exhaustively evaluated so far. In the present study we experimentally analyzed performances of all stent retrievers available into the French market up to Juin 2015. The aim of this study was to identify any device feature that was functional to the thrombus removal.Stent retrievers were evaluated by mechanical and functional test: mechanical tests were performed in order to investigate devices radial force, the aim was to evaluate the radial force exerted by the stent in two specific conditions: upon deployment and during the retrieval.Functional tests were aimed to visually evaluate the stent retriever’s ability in remaining in close apposition to the vessels wall and to maintain the thrombus engaged within its struts during the retrieval. We evaluated the interaction of the devices with thrombi of different features and sizes that we generated using human blood in order to obtain two types of clot: one softer “red type” that was composed by all elements of the whole blood and one stiffer “white type” that was mainly composed by platelet-rich plasma. Such tests were conducted using a rigid 3D printed vascular model reproducing the brain anterior circulation. Two neuro-interventionalists with experience in thrombectomy procedures performed functional tests, each experiment was filmed and two authors thereafter conducted visual analysis of the results.Mechanical tests showed different behavior in terms of radial pressure variation during retrieval for each stent. Constant radial pressure during retrieval was related to constant cohesion over the vessel wall during retrieval and higher rate of clot removal efficacy. All stent retrievers slide over the clot failing in clot removal when interact with white large thrombi (diameter&gt;6 mm)
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Aleu, Bonaut Aitziber. "Stentriever thrombectomy for stroke within and beyond the time window." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/393973.

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Recientemente se ha aprobado el tratamiento endovascular(TEV) para el ictus por oclusión de gran vaso, lo cual ha cambiado radicalmente el pronóstico infausto de estos pacientes. Una de las contraindicaciones para el TEV es que el paciente llegue más alá de la ventana terapéutica (VT), que tradicionalmente era de 8 horas y actualmente es de 6 horas. La VT se define como el tiempo transcurrido desde el inicio de los síntomas hasta la punción femoral. En pacientes en quienes el inicio del ictus es desconocido, bien porque ocurrió durante el sueño o bien porque el paciente no puede decirlo y no había testigos, la hora de inicio se considera la última vez que el paciente fue visto bien. Estos pacientes caen fuera de VT porque llegan demasiado tarde para ser tratados. Otros pacientes que quedan fuera de VT, son aquellos que tienen una hora de inicio conocida pero que llegan tarde al hospital. Sin embargo, existen evidencias crecientes que la velocidad a la que progresa la isquemia tras una oclusión arterial, varia notablemente entre individuos. Así, mientras que en unos pacientes el territorio arterial está infartado en 6 horas, en otro puede que el infarto no esté establecido hasta las 10 horas. Este concepto choca con el enfoque actual de tratamiento basado en el tiempo, que establece que un paciente se trate en función del tiempo desde el inicio siempre que no haya un gran área infartada. En enfoque basado en la viabilidad del tejido ignora la hora de inicio del ictus. Así para tratar o no a un paciente, se realiza una neuroimagen para confirmar que hay tejido viable, si es así, se realiza el TEV independientemente del tiempo transcurrido. Hay estudios randomizados en marcha para demostrar esta hipótesis, y se han publicado estudios concluyendo que la seguridad y el buen pronostico es similar en pacientes fuera y dentro de ventana. Sin embargo, la mayoría de dichos estudios fueron realizados con dispositivos de primera generación, y algunos reportan pacientes de circulación anterior y posterior. Los stentrievers(ST), dispositivos de nueva generación han demostrado mayores tasas de recanalización y buen pronostico, de hecho las guías actuales recomiendan el TEV con ST. El objetivo primario de esta tesis fue comparar la seguridad y pronóstico de pacientes con ictus de circulación anterior fuera de ventana, tratados mediante TEV con ST, con los pacientes dentro de ventana(WTW). De un total de 468 pacientes 292(63.4%) estaban fuera de ventana(OTW) y 176(37.6%) dentro de ventana. El grupo fuera de ventana, se dividió en dos subgrupos de acuerdo a la hora de inicio: desconocida (UKO) in 113 (24.1%)pacientes y conocida con presentación tardía (KO-LP) en 63(13.5%) pacientes. Estos subgrupos no se pudieron agrupar en el grupo OTW porque un análisis estadístico previo mostró que no eran comparables. Por tanto, los resultados de estos pacientes se presentan de modo separado y comparados con pacientes dentro de ventana. No se encontraron diferencias significativas en buen pronóstico a 3 meses, con 49% en WTW, 42.2%% en UKO y 37.3% en KO-LP. Respecto a la seguridad, tampoco se encontraron diferencias en hemorragia intracraneal sintomática (6.2%WTW, 2.7%UKO y 9.5%KO-LP). Estos hallazgos apoyan el enfoque de viabilidad tisular en vez del basado en tiempo, en pacientes con ictus de circulación anterior tratados con EVT y ST, y seleccionados por neuroimagen, hasta que estén disponibles los resultados de los estudios randomizados. De ser positivos, uno de cada 3 pacientes que normalmente no se tratan por estar fuera de la VT podría ser tratado según nuestro estudio.<br>Endovascular therapy (EVT) for stroke due to large vessel occlusion has been recently approved, changing dramatically the outcome of these patients, who otherwise would have a dismal outcome. However, there are patients automatically excluded from EVT because they arrive beyond the therapeutic time window. Traditionally, the time window (TW) for EVT has been 8 hours but the recent guidelines shortened the window to 6 hours. The TW is defined as the time from symptom onset to the time of groin puncture. In patients in whom the stroke onset is unclear either because the stroke occurred while sleeping or because the patient is unable to tell the onset because is aphasic on unconscious, and no witness is available, the onset is considered the last time the patient was seen normal. These patients often fall outside the window (OTW), because are too late to be treated. Other patients that are too late to be treated are those who, despite having a clear time of onset, arrive OTW. However, there is growing evidence showing that the speed at which the ischemia evolves after an arterial occlusion, varies significantly among individuals. Thus, while in some patients the arterial territory is infarcted in 6 hours, in other, the infarct might not be established after 10 hours. This concept radically challenges the current time-based approach, which establishes whether a patient should be treated or not based on the time from onset provided there is not a large area of infarcted tissue. Interestingly, the tissue-based approach disregards the time from onset. Consequently, the criteria to decide whether to treat a patient or not, would be to image the brain to find out if there is viable tissue, if so, treatment should be carried forward irrespective of the time since stroke onset. There are ongoing trials to prove this hypothesis, and non-controlled studies have been published showing that patients treated OTW have comparable safety and favorable outcomes than those treated within the window. However, those studies were performed with first generation devices and some refer to anterior and posterior circulation strokes. Regarding new generation strategies, stentrievers (ST) have demonstrated higher rates of recanalization and better outcomes. Current guidelines recommend the use of ST. The primary aim of this work was to compare the outcomes and safety of patients OTW with stroke due to anterior circulation (AC) occlusion treated with EVT with ST and selected by neuroimaging with the safety and outcomes of patients WTW. From a total of 468 patients, 292(63.4%) were patients WTW and 176 (37.6%)OTW. The group OTW was divided in two subgroups according to onset: unknown time of onset (UKO) in 113 (24.1%) patients and known onset but late presenters (KO-LP) in 63 (13.5%) patients. These subgroups could not be merged because p statistical analysis showed that they were not comparable, thus, the results had to be presented separately and compared with the WTW group. Regarding outcome, there were no significant differences good outcome at 3 months, with rates of 49% in WTW, 42.2%% in UKO and 37.3% in KO-LP. Regarding safety, there were no significant differences in symptomatic intracranial hemorrhage across groups (6.2%WTW, 2.7%UKO y 9.5%KO-LP). These findings support the tissue- based approach in patients with stroke due to AC occlusion treated with EVT using ST, and selected by neuroimaging, until the results of the randomized trials arrive. According to our study, a positive result would have a great impact on at least, one out of three patients that arrive OTW and are currently left untreated.
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Lin, Hannah. "Factors Associated with Mortality After Undergoing Thrombectomy for Acute Ischemic Stroke." eScholarship@UMMS, 2020. https://escholarship.umassmed.edu/gsbs_diss/1085.

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Background: Mechanical thrombectomy is the gold standard for treating patients with certain acute ischemic stroke (AIS) due to large vessel occlusion (LVO). However, even with major advancements and increasing procedural volumes, acute endovascular therapy remains a high-risk procedure with a considerable 90-day mortality rate, affected by a variety of factors. Purpose: To investigate various clinical and procedural factors associated with 90-day mortality in patients undergoing mechanical thrombectomy for emergent treatment of AIS and determine which of these factors made unique contributions to post-thrombectomy prognosis. Methods: We examined a prospective registry of 323 patients treated with endovascular thrombectomy for AIS between 2016 and 2019 at a high-volume comprehensive stroke center in central Massachusetts. We developed two multivariable logistic regression models adjusting for the contributions of baseline characteristics and recanalization parameters, to identify potential predictors of mortality at 90 days. Results: Among 323 AIS patients treated with mechanical thrombectomy, the overall rate of successful recanalization was 86% and the overall post-procedure mortality rate was 29% by 90 days. After univariate analysis, a baseline multivariable model comprised of: history of stroke (OR 0.28, 95% CI 0.09 – 0.68), pre-stroke modified Rankin Scale (mRS 2: OR 3.75, 95% CI), severe admission National Institutes of Health Stroke Scale (NIHSS 21–42: OR 12.36, 95% CI 1.48 – 103.27), internal carotid artery (ICA) occlusion (OR 2.77, 95% CI 1.18 – 6.55), and posterior circulation occlusion (OR 2.69, 95% CI 1.06 – 6.83) was prognostic of 90-day mortality. A second multivariable model also found the procedural factors of: clot obtained after each pass (OR 0.49, 95% CI 0.24 – 1.00), successful recanalization (OR 0.21, 95% CI 0.06 – 0.8) and symptomatic intracranial hemorrhage (sICH; OR 17.89, 95% CI 5.22 – 61.29) to be identifiable predictors of post-thrombectomy mortality. Conclusion: Death within 90 days after thrombectomy was increased among patients with higher pre-stroke disability, higher stroke severity on admission, ICA or posterior occlusion, and those with sICH complication. A history of stroke, clot extraction after each device pass, and successful recanalization are associated with decreased 90-day mortality. These identifiable contributors may inform patient selection, prognosis evolution, and shared decision-making regarding emergent thrombectomy for treatment of AIS.
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Ommen, G. V. A. van. "The hydrolyser a hydrodynamic thrombectomy catheter to remove thrombi from the cardiovascular system /." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1998. http://arno.unimaas.nl/show.cgi?fid=8394.

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Koludrovich, Michael. "Design, Analysis, and Experimental Evaluation of a Superelastic NiTi Minimally Invasive Thrombectomy Device." University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1399370551.

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Seners, Pierre. "Recanalisation artérielle précoce après thrombolyse intraveineuse d’un accident ischémique cérébral avec occlusion artérielle proximale : incidence, prédiction et physiopathologie Indicidence and predictors of early recanalization following IV thrombolysis. A systematic review and meta-analysis Post-thrombolysis recanalization in stroke referrals for thrombectomy: Incidence, predictors and prediction scores Relationships between brain perfusion and early recanalization after intravenous thrombolysis for acute stroke with large vessel occlusion Better collaterals are independently associated with post-thrombolysis recanalization before thrombectomy Thrombus length predicts lack of post-thrombolysis early recanalization in minor stroke with large vessel occlusion Early recanalization in tenecteplase vs. alteplase-treated drip-and-ship patients referred for thrombectomy." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCB222.

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À la phase aigüe de l’accident ischémique cérébral (AIC) avec occlusion artérielle proximale, la cible thérapeutique principale est l’obtention d’une recanalisation artérielle la plus rapide possible. L’utilisation combinée de la thrombolyse intraveineuse (TIV) par alteplase et de la thrombectomie mécanique (TM), dénommée « bridging therapy » et recommandée depuis 2015, est actuellement remise en question car i) en cas de faible probabilité de recanalisation précoce (RP) post-TIV, celle-ci pourrait être non seulement inutile, mais aussi délétère ; et ii) inversement, si la probabilité de RP est forte, un transfert en centre spécialisé pour TM pourrait s’avérer inutile. Une meilleure compréhension des mécanismes physiopathologiques sous-tendant la résistance à la TIV, et le développement d’outils prédictifs de la survenue de celle-ci, pourraient avoir des implications cliniques importantes, notamment le développement de thérapies intraveineuses plus efficaces ou l’avancée vers une médecine personnalisée sélectionnant le traitement de recanalisation (c’est-à-dire, TIV seule, bridging ou TM seule) le plus adapté à chaque patient. Dans cette thèse, nous avons étudié l’incidence et les facteurs prédictifs de la RP post-TIV dans une large cohorte multicentrique française d’AIC avec occlusion proximale (n=1107), traités par TIV et adressés pour TM entre 2015 et 2017. La RP était évaluée dans les 3h suivant la TIV, sur le premier jet de l’artériographie ou par imagerie vasculaire non-invasive. Notre travail a montré que l’incidence de la RP post-TIV est relativement importante, survenant en moyenne chez 1 patient sur 5. L’analyse des facteurs prédictifs a montré que la localisation du thrombus dans l’arbre artériel, sa longueur, le délai entre la TIV et l’évaluation de la recanalisation, et la qualité du réseau artériel collatéral ou la sévérité de l’hypoperfusion cérébrale, sont associés de manière indépendante à la survenue d’une RP, contribuant de ce fait à la compréhension des mécanismes sous-tendant celle-ci. Un score prédictif original, créé par combinaison des trois premières variables, permettait de prédire l’absence de RP avec une très grande spécificité, mais de façon insuffisamment fiable la survenue d’une RP. Ce score devrait permettre à l’avenir d’aider à la sélection des patients pour des essais randomisés comparant bridging vs. TM seule, mais pas de limiter les « transferts futiles » en TM. Dans le sous-groupe de patients avec déficit neurologique mineur (score NIHSS&lt;6), situation dans laquelle le traitement optimal est actuellement incertain, nous avons montré que la longueur du thrombus est un facteur prédictif puissant de RP, et qu’un seuil de 9mm permet de prédire l’absence de RP avec un bon rapport sensibilité/spécificité, ce qui pourrait aider au dessin d’essais randomisés testant TIV seule vs. bridging dans cette population. Enfin, dans un échantillon de patients nécessitant un transfert inter-hospitalier pour la réalisation de la TM, situation clinique la plus fréquente actuellement, l’incidence de RP n’était pas différente entre patients thrombolysés par tenecteplase (un nouveau thrombolytique prometteur) en comparaison à l’alteplase. La divergence de ce résultat avec ceux de l’essai randomisé de phase II EXTEND-IA TNK qui a rapporté une incidence deux fois plus élevée de RP après tenecteplase dans une population admise directement dans un centre de TM (chez qui le délai thrombolyse-thrombectomie était donc nettement plus court), s’expliquerait par une recanalisation plus précoce après tenecteplase, ce qui, en cas de confirmation par des études futures, pourrait avoir des conséquences cliniques importantes. (...)<br>In acute stroke patients with large-vessel occlusion (LVO), the goal of intravenous thrombolysis (IVT) is to achieve early recanalization. Whether all patients with LVO need to undergo intravenous thrombolysis (IVT) before mechanical thrombectomy (MT) – i.e. bridging therapy, which is standard-of-care since 2015 – is debated as: i) thrombolysis may be harmful in patients unlikely to recanalize following IVT; and, ii) conversely, transfer for MT may be unnecessary in patients highly likely to recanalize. It is therefore timely and important to investigate the mechanisms and predictors of post-IVT recanalization, since the findings could have major clinical implications, such as the development of more efficient intravenous therapies, as well as moving towards personalized medicine, involving the selection of individual patients for best therapy, i.e., IVT alone, bridging, or MT alone. In the present thesis, we studied the incidence and predictors of post-IVT early recanalization in a large French multicentric cohort of acute stroke with LVO (n=1107), where all patients were treated with IVT and referred for MT between 2015 and 2017. Recanalization was evaluated on first intracranial angiogram or non-invasive vascular imaging within the first 3h following IVT start. The incidence of early recanalization following IVT was substantial in the overall cohort, occurring in ~1 in 5 patients. Thrombus site and length, time elapsed between IVT start and recanalization assessment, and quality of the leptomeningeal collateral flow or severity of hypoperfusion, were all independently associated with early recanalization occurrence. These findings are novel and important, and shed new light on the mechanisms underlying post-IVT recanalization. A six-point score derived from the three former variables afforded &gt;90% specificity for no-recanalization, but did not reliably predict occurrence of early recanalization. This score should prove of value for patient selection into trials, testing e.g. bridging therapy vs. MT alone, but may not be used to support decisions to withhold referral for MT. In the subgroup of LVO patients with minor neurological symptoms (NIHSS score &lt;6), in whom the optimal treatment is unknown, we found that thrombus length was a powerful independent predictor of no-recanalization, and that the optimal cutoff (9mm) had a high sensitivity/specificity ratio for no-recanalization, which may help design randomized trials aiming to test bridging therapy vs. IVT alone in this population. Lastly, unlike the EXTEND-IA TNK randomized trial which found 2-fold higher early recanalization rate before mechanical MT following IVT with tenecteplase as compared to alteplase in patients directly admitted to MT-capable centres, we found similar early recanalization rates with these two thrombolytic agents in patients transferred for MT from a non MT-capable centre (i.e., with longer IVT-to-MT delays than in EXTEND-IA TNK), currently the most frequently encountered clinical situation. Taken together, these data suggest that recanalization may occur earlier with tenecteplase, which if confirmed would have clinical relevance. Towards further clarifying the pathophysiology of post-thrombolysis early recanalization failure and develop more efficient intravenous therapies for acute ischemic stroke, specific studies will need to address two additional potentially important predictors of early recanalization, namely haemostatic biomarkers and thrombus composition
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QUAGLIANA, Angelo. "TROMBECTOMIA INTRACORONARICA CON NeVA STENT RETRIEVER IN PAZIENTI AFFETTI DA SINDROME CORONARICA ACUTA: ESPERIENZA MULTICENTRICA FIRST-IN-MEN." Doctoral thesis, Università degli Studi di Palermo, 2021. http://hdl.handle.net/10447/479107.

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Gory, Benjamin. "Caractérisation IRM d’un modèle murin d’ischémie-reperfusion cérébrale induit par cathétérisme de l’artère cérébrale moyenne et évaluation du post-conditionnement à la Cyclosporine A." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1208/document.

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La reperfusion complète et précoce est le moyen le plus efficace pour limiter l'extension de l'infarctus cérébral et les séquelles neurologiques. Le traitement de l'infarctus cérébral a été révolutionné par la thrombectomie mécanique intra-artérielle en permettant une recanalisation dans plus de 70% des cas et une réduction significative de la morbidité comparativement à la thrombolyse seule pour le territoire carotidien. Le pronostic des occlusions basilaires reste dramatique et aucun essai n'a démontré le bénéfice de l'approche intra-artérielle à l'heure actuelle. Dans la première partie du travail, nous avons réalisé une méta-analyse sur la thrombectomie par «stent-retriever» des occlusions basilaires, à partir des résultats publiés dans MEDLINE entre novembre 2010 et avril 2014: recanalisation angiographique (TICI≥2b)=81% (IC 95%: 73-87); hémorragie cérébrale symptomatique à 24 heures=4% (IC 95%: 2-8); évolution neurologique favorable (mRS≤2 à 3 mois)=42% (IC 95%: 36-48); mortalité=30% (IC 95%: 25-36). L'approche intra-artérielle ouvre une nouvelle ère thérapeutique, cependant un modèle animal adapté et pertinent est nécessaire pour l'évaluation pré-clinique. Dans la deuxième partie du travail, nous avons caractérisé l'évolution spatio-temporelle précoce de l'infarctus par IRM multimodale dans un modèle d'ischémie cérébrale focale transitoire réalisé par occlusion sélective intra-artérielle de l'artère cérébrale moyenne chez le rat adulte. Une occlusion complète de l'artère cérébrale moyenne proximale était observée dans 75% des 16 rats opérés, et un mismatch diffusion/perfusion dans 77% des cas. Le volume ischémique durant l'occlusion artérielle, définie sur la séquence de diffusion, était de 90±64 mm3 et de 57±67 mm3 à 24 heures sur la séquence T2. La recanalisation artérielle s'associe à une reperfusion tissulaire dans 36% des cas. L'hypoperfusion persistait chez la majorité des animaux 3 heures après recanalisation. L'infarctus était de localisation cortical dans 31%, striatale dans 25%, et cortico-striatale dans 44%. Tous les animaux étaient en vie à 24 heures confirmant le caractère mini-invasif de ce modèle. Bien que la reperfusion sauve incontestablement une partie du parenchyme ischémique, elle s'accompagne également de lésions irréversibles spécifiques, dites de reperfusion, s'ajoutant aux lésions initiales. Limiter l'importance des lésions de reperfusion représente un objectif thérapeutique majeur. Dans la troisième partie, nous avons testé l'effet neuroprotecteur de la Cyclosporine A sur la réduction du volume de l'infarctus cérébral et sur le pronostic clinique. Une procédure d'ischémie reperfusion cérébrale de 60 minutes a été réalisée chez 48 animaux, puis ont été randomisés en quatre groupes (groupe témoin, pré-conditionnement, postconditionnement intraveineux et intra-artériel avec la Cyclosporine A à la dose de 10 mg/kg dans les 30 secondes suivant la reperfusion). Sur les 43 animaux inclus dans l'analyse, il n'a pas été observé de réduction du volume ischémique ni une amélioration du pronostic après injection intraveineuse ou intra-artérielle de Cyclosporine A. La Cyclosporine A ne permet pas non plus de limiter l'extension des lésions de reperfusion au sein de la zone à risque à 24 heures de la reperfusion cérébrale<br>Early and complete reperfusion is the most effective therapy to limit the extent of brain infarction. The treatment of acute anterior ischemic stroke has been revolutionized by the intra-arterial mechanical thrombectomy allowing a 70% recanalization rate and a significant reduction of morbidity compared with thrombolysis alone. The prognosis of basilar artery occlusion remains catastrophic, and to date any trial has demonstrated the benefit of intra-arterial approach. In the first part of the work, we conducted a systematic review and meta-analysis of all previous studies of stent retriever thrombectomy in basilar artery occlusion patients between November 2010 and April 2014: recanalization (TICI≥2b)=81% (95% CI: 73-87); symptomatic intracranial haemorrhage at 24 hours=4% (95% CI 2-8); favorable neurological outcome (mRS≤2 at 3 months)=42% (95% CI: 36-48); mortality=30%(95% CI 25-36). Intra-arterial approach opens new avenues for the developement of treatments for brain infarction, but a relevant animal model of acute ischemic stroke is required for preclinical evaluation. In the second part of the work, we evaluated the spatiotemporal evolution of cerebral ischemia by sequential multimodal MRI in a new minimally invasive model of transient focal ischemia by selective intra-arterial occlusion of the middle cerebral artery in rat. A complete occlusion of the proximal portion of the middle cerebral artery was observed in 75% of 16 operated rats, and a mismatch diffusion/perfusion in 77% of cases. Acute stroke volume during arterial occlusion was 90±64 mm3 on diffusion-weighted imaging, and 57±67 mm3 at 24 hours on T2-weighted imaging. Recanalization is associated with tissue reperfusion in 36% of cases. The hypoperfusion persisted in the majority of animals 3 hours after recanalization. Brain infarction was cortical in 31%, striatal in 25%, and corticalstriatal in 44% of cases. All animals were alive at 24 hours, confirming the minimally invasive nature of the model. Although reperfusion saves a portion of ischemic tissue, it also carries specific irreversible damage, called reperfusion injury, in addition to initial damage caused by ischemia. Limiting the size of infarction is a major objective. In the third part, we tested the neuroprotective effect of Cyclosporine A in reducing the lesion volume and functional outcome. A total of 48 adult rats underwent the intra-arterial ischemia reperfusion procedure, and were randomly assigned to four treatment groups (control, preconditioning, intravenous and intra-arterial postconditioning with Cyclosporine A). Intravenous or intra arterial injection of Cyclosporine A at reperfusion does not either reduce the volume of stroke or improve the neurological outcome. Administation of Cyclosporin A at reperfusion does not limit the extension of reperfusion injuries within the ischemic risk area at 24 hours
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Puffer, Andrew James. "Design and Testing of a Minimally Invasive Blood Clot Removal Device Constructed With Elements of Superelastic Nitinol." University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1399558753.

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Wateau, Océane. "Mise au point et caractérisation fonctionnelle d'un modèle d'ischémie-reperfusion cérébrale chez le Macaque cynomolgus A non-human primate model of stroke reproducing endovascular thrombectomy and allowing long-term imaging and neurological read-outs." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC401.

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L’accident vasculaire cérébral est une pathologie dévastatrice et constitue l’une des premières causes de handicap acquis dans le monde. La thrombectomie mécanique par voie endovasculaire est en train de changer drastiquement la prise en charge de l’AVC ischémique à la phase aiguë, en permettant une reperfusion rapide des tissus hypoperfusés et en réduisant la taille de l’infarct final. Bien que la reperfusion soit sans aucun doute bénéfique, elle peut également causer des lésions irréversibles des tissus, dites « d’ischémie-reperfusion ». Par conséquent, le développement de stratégies dites neuroprotectrices est essentiel pour contrer ces évènements délétères. Dans ce contexte, des modèles expérimentaux pertinents sont nécessaires pour tester de nouvelles thérapies et répondre à des questions importantes relatives à la progression de l’infarctus malgré une recanalisation réussie, la réversibilité des lésions ischémiques, la perturbation de la barrière hémato-encéphalique, les dommages de reperfusion, tout cela dans le but d’améliorer la récupération fonctionnelle post-infarctus. Durant ma thèse, nous avons développé un nouveau modèle non invasif d’ischémie-reperfusion cérébrale chez le primate non humain (Macaca fascicularis) reposant sur une approche endovasculaire peu invasive permettant une occlusion transitoire de l’artère cérébrale moyenne, puis sa reperfusion. La première partie de mes travaux a été consacrée à la mise au point de la méthode d’occlusion et du suivi neurofonctionnel des animaux grâce à l’utilisation de 3 outils que j’ai développés : une échelle d’évaluation neurologique, un test de dextérité manuelle et un test de réponse différée. La seconde partie de mes travaux a consisté à valider le modèle nouvellement développé et à le caractériser. Nous avons ainsi réussi à évaluer les dommages cérébraux per- et post-occlusion par des mesures innovantes d’imagerie (TEP-IRM multiparamétriques) ainsi que les déficits neurologiques des animaux sur le long terme. Ce nouveau modèle translationnel, proche de la réalité clinique, constitue un outil essentiel et innovant pour la recherche de cibles thérapeutiques visant à améliorer l’efficacité des traitements dans cette nouvelle ère de la thrombectomie<br>Stroke is a devastating disease and is one of the first causes worldwide of acquired disability. Endovascular mechanical thrombectomy is dramatically changing the management of acute ischemic stroke, allowing a quick reperfusion of hypoperfused tissues and reducing the size of the final infarct. Although reperfusion is undoubtedly beneficial, it can also cause irreversible tissue damage. Therefore, the development of so-called neuroprotective strategies is essential to counteract these deleterious events. In this context, relevant experimental models are required for testing new therapies and addressing important questions about infarct progression despite successful recanalization, reversibility of ischemic lesions, blood-brain barrier disruption, reperfusion damage all with the goal of improving functional recovery post-infarction. During my thesis, we developed a minimally invasive non-human primate model of cerebral ischemia-reperfusion (Macaca fascicularis) based on an endovascular approach allowing transient occlusion and recanalization of the middle cerebral artery and its reperfusion. The first part of my work was devoted to the development of the occlusion method and the neurofunctional monitoring of animals thanks to the use of three tools that I developed: a neurological evaluation scale, a hand dexterity task and a delayed response task. In the second part of my work, I validated and characterized the newly developed model. We have thus succeeded in evaluating the brain damages per- and post-occlusion by innovative imaging methods (multiparametric PET-MRI) as well as assessing the long-term neurological deficits of the animals. This new model, similar to the clinical reality, is an essential and innovative tool for the search for therapeutic targets to improve the effectiveness of treatments in the new era of mechanical thrombectomy
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Books on the topic "Thrombectomy"

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Samaniego, Edgar A., and David Hasan, eds. Acute Stroke Management in the Era of Thrombectomy. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17535-1.

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Kahn, S. Lowell. Distal Occlusion Thrombectomy Technique. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0022.

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The distal occlusion balloon thrombectomy technique involves placement of an occlusion balloon immediately distal to the thrombus or embolus. The balloon overlaps the antegrade wire. With the balloon inflated, the thrombotic/embolic material is removed over the antegrade wire using the desired thrombectomy catheter or device. The inflated balloon prevents distal migration of the embolic material during removal. Intermittent digital subtraction angiography is performed to assess for residual debris. When sufficiently extracted, the balloon is deflated and removed. Most commonly, this is performed with the balloon inserted in a retrograde manner. However, if distal access is not feasible, the antegrade sheath can be upsized.
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Abramowicz, A. Elisabeth. Endovascular Thrombectomy in Acute Ischemic Stroke. Edited by David E. Traul and Irene P. Osborn. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190850036.003.0009.

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Endovascular thrombectomy (EVT) for acute ischemic stroke is a new and powerful treatment modality that restores functional independence to many victims. Although it has been proved of value in large-vessel occlusion of the anterior circulation, it is also used in basilar artery embolism. Time to successful reperfusion is a major determinant of recovery. A subset of patients has robust collaterals and will benefit from treatment up to 24 hours after stroke onset; the presence of salvageable brain tissue (penumbra) must be ascertained by specialized imaging. The number of patients who can benefit from EVT is estimated at 100,000/year in the United States alone in more than 300 designated Thrombectomy-Capable Stroke Centers. EVT is a new anesthetic emergency. Anesthesiologists must be actively involved in creating protocol-driven care for acute ischemic stroke patients.
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Nam, Hyo Suk, and Byung Moon Kim, eds. Thrombolysis and Thrombectomy in Acute Ischemic Stroke. MDPI, 2023. http://dx.doi.org/10.3390/books978-3-0365-7599-5.

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Samaniego, Edgar A., and David Hasan. Acute Stroke Management in the Era of Thrombectomy. Springer, 2019.

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Cowling, Mark G., and L. Baert. Vascular Interventional Radiology: Angioplasty, Stenting, Thrombolysis and Thrombectomy. Springer London, Limited, 2006.

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Samaniego, Edgar A., and David Hasan. Acute Stroke Management in the Era of Thrombectomy. Springer International Publishing AG, 2020.

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Kahn, S. Lowell. Directional AngioJet Thrombectomy with Guide Catheter Helical Spin Technique. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0037.

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The presence of thrombus in the central veins is associated with a higher risk of development post-thrombotic syndrome. The AngioJet Solent Proxi (90 cm) and Omni (120 cm) catheters are commonly used peripheral thrombectomy devices indicated for acute arterial and venous thrombus removal. Both catheters are 6 Fr sheath/8 Fr guide catheter compatible, and both offer the Power Pulse feature, allowing the direct infusion of tissue plasminogen activator into the thrombus. The catheters are indicated for use in vessels greater than 3 mm, with an optimal vessel range between 6 and 20 mm. Their use in the removal of iliac vein and inferior vena cava thrombus is frequent. Although the system is purported to provide effective thrombectomy capabilities in larger vessels, incomplete thrombus removal is common with larger vessels. This chapter proposes a simple modification in the standard use of the AngioJet Solent Proxi and Omni catheters.
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Thrombectomy - Recent Advances in Ischaemic Damage Treatment [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.94682.

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Irani, Zubin, and Sara Zhao. Dual and Balloon-Assisted AngioJet Thrombectomy for Iliofemoral Deep Venous Thrombosis. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0038.

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Lower extremity deep venous thrombosis (DVT) may be complicated by pulmonary embolism, post-thrombotic syndrome, and phlegmasia cerulea dolens. Due to these complications, the American Venous Forum now recommends thrombus removal for large or symptomatic thrombus burden. The AngioJet Solent Proxy and Omni thrombectomy sets are indicated for use in iliofemoral and lower extremity veins with a diameter ≥3 mm. The device has quickly become a preferred device among the available mechanical thrombectomy options. The AngioJet system has been demonstrated as both efficacious and safe as a method of thrombectomy in lower extremity DVT. This chapter discusses two techniques to utilize the AngioJet device in iliofemoral DVT.
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Book chapters on the topic "Thrombectomy"

1

Roth, Elliot J. "Thrombectomy." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_9278.

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Roth, Elliot J. "Thrombectomy." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-56782-2_9278-1.

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Nachbur, Bernard H. "Venous thrombectomy." In Vascular Surgery. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4899-6854-8_52.

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Plate, Gunnar. "Venous Thrombectomy." In Textbook of Angiology. Springer New York, 2000. http://dx.doi.org/10.1007/978-1-4612-1190-7_91.

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Gottlob, Rainer, and Robert May. "Venous Thrombectomy." In Venous Valves. Springer Vienna, 1986. http://dx.doi.org/10.1007/978-3-7091-8827-9_11.

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Hoballah, Jamal J. "Thrombectomy–Embolectomy." In Vascular Reconstructions. Springer New York, 2021. http://dx.doi.org/10.1007/978-1-0716-1089-3_6.

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Goh, Gerard S., Robert Morgan, and Anna-Maria Belli. "Thrombolysis, Mechanical Thrombectomy and Percutaneous Aspiration Thrombectomy." In Medical Radiology. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/174_2012_568.

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Hawkes, Christine, Kavit Shah, and Tudor G. Jovin. "Thrombolysis and Thrombectomy." In Posterior Circulation Stroke. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6739-1_11.

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Dunn, Marilyn E., and Chick Weisse. "Thrombectomy and Thrombolysis." In Veterinary Image-Guided Interventions. John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118910924.ch47.

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Comerota, Anthony J., and Rodrigo Ruiz-Gamboa. "Operative venous thrombectomy." In Endovascular and Open Vascular Reconstruction. CRC Press, 2017. http://dx.doi.org/10.1201/9781315113845-58.

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Conference papers on the topic "Thrombectomy"

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Chueh, Ju-yu, Anna Luisa Kuhn, Ajit S. Puri, Ajay K. Wakhloo, and Matthew J. Gounis. "The Use of Stentrievers in Acute Ischemic Stroke: Performance Evaluation in a Patient-Specific Vascular Replica." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14634.

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Expedited revascularization through pharmacologic dissolution and/or mechanical thrombectomy is the principle goal of treatment of ischemic stroke [1]. Pharmacologic therapy consists of intravenous thrombolysis with tissue plasminogen activator and is limited by a narrow time window within which to administer the medication, resulting in less than 10% utilization in stroke patients. Mechanical thrombectomy provides another option for flow recanalization. Four thrombectomy devices are cleared by the FDA to restore blood flow in ischemic stroke patients, namely, the Merci retriever, the Penumbra aspiration system, the Solitaire FR revascularization device, and the Trevo device. While several completed and ongoing clinical trials have shown enhancement in the design of thrombectomy devices and increase in recanalization rate [2–4], the recanalization rate and, more importantly, the clinical outcome achieved with current thrombectomy devices still remain to be optimized.
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Montes, Enrique. "Double-Stent Retriever Thrombectomy." In PAIRS Annual Meeting. Thieme Medical and Scientific Publishers Pvt. Ltd., 2020. http://dx.doi.org/10.1055/s-0041-1729007.

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Gorantla, A., H. Taluru, M. Pillai, et al. "Cardiac Tamponade After Thrombectomy." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1804.

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Rodriguez-Calienes, Aaron, Milagros Galecio-Castillo, Mudassir Farooqui, et al. "Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions (S24.003)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000203653.

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Guenego, Adrien, Michel Piotin, Franny Hulscher, and Robert Fahed. "Thrombectomy Technique Predicts Hemorrhagic Transformation Risk after Thrombectomy in Basilar artery Stroke." In Presentation Abstracts. Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1740844.

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Castleman, M., T. Browning, and S. Singh. "Post-Thrombectomy Reperfusion Pulmonary Edema." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2231.

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Brake, A., L. Fry, C. Heskett, et al. "O-008 Endovascular thrombectomy outcomes stratified by hospital thrombectomy volume: a national inpatient sample study." In SNIS 20th Annual Meeting Abstracts. BMJ Publishing Group Ltd., 2023. http://dx.doi.org/10.1136/jnis-2023-snis.8.

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Schmiech, Jonte, Helena Guerreiro, Nadine MacMillan, et al. "Quantitative Analysis of Periprocedural Thrombus Fragmentation using an Automated Optical Detection System in a Comprehensive Stroke Intervention Training Platform." In 2025 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2025. https://doi.org/10.1115/dmd2025-1017.

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Abstract Mechanical thrombectomy for occluded large brain vessels in acute ischemic stroke has proven highly effective, but periprocedural thrombus fragmentation (PTF) remains a significant challenge that can lead to downstream embolization and incomplete recanalization. While laboratory methods exist for detailed PTF analysis, practical solutions are needed for quantitative assessment of simulated thrombectomy procedures performed on physical training models. We present a novel measurement system that enables automated detection and quantification of thrombus fragmentation events during simulated thrombectomy procedures on the HANNES neurointerventional simulator. The system employs a six-channel measurement chamber with integrated UV illumination and an optical detection setup to track fluorescent thrombus fragments. Fragments are automatically detected, assigned IDs, and measured in real-time using computer vision techniques. Validation studies comparing the system's measurements to microscopic analysis demonstrated strong correlation (Pearson's r=0.9939, p&amp;lt;0.001). In controlled testing, the system achieved 100% sensitivity and specificity for single fragment detection, successfully measuring fragments as small as 642 μm in radius. While adhering fragments are currently treated as quantify PTF events in real-time provides an objective basis for evaluating procedural performance and comparing thrombectomy techniques in training scenarios. This novel measurement system represents a practical advance for studying thrombus fragmentation in educational settings. Integration into comprehensive training platforms like HANNES could improve understanding and management of PTF risks, potentially leading to better patient outcomes through enhanced operator training. Future studies correlating PTF metrics with physician experience and clinical results may establish performance benchmarks to help quantify individual proficiency and predict clinical competency.
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Veiga, V. C., P. Travassos, M. Pitaci, et al. "Experience with Mechanical Thrombectomy in Ischemic Stroke." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3568.

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Kattih, Z., B. Bass, J. A. Moore, A. Mahajan, and B. A. Mina. "Emergent Thrombectomy Over Thrombolysis for Expansive Clots." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6808.

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Reports on the topic "Thrombectomy"

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Sirakov, Stanimir, and Alexander Sirakov. Single Centre Experience of Thrombectomy in Acute Ischemic Stroke. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2019. http://dx.doi.org/10.7546/crabs.2019.11.15.

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peng, min, Zhuoyou Chen, Jianfang Liu, and Hongran Fu. Efficacy and safety of teneplase and alteplase before mechanical thrombectomy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0128.

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Bao, QiangJi, YunTing Li, YiMing Li, XiaoQiang Zhang, XiaoLong Huang, and Hui Zhou. Meta-analysis of the safety and efficacy of intensive blood pressure control after thrombectomy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.6.0008.

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Yang, Lu, Jialin Liu, Ruisheng Duan, and Hao Wang. Efficacy and safety of endovascular mechanical thrombectomy for cerebral venous sinus thrombosis: meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2025. https://doi.org/10.37766/inplasy2025.4.0001.

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Zhang, Yu. Endovascular Thrombectomy for Stroke Due to Basilar-Artery Occlusion: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.10.0088.

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Wang, Zekun, kangxiang Ji, and Qi Fang. Endovascular thrombectomy for stroke due to acute basilar-artery occlusion: A systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0063.

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Review question / Objective: The objective of this systematic review and meta-analysis was to compare the efficacy and safety of endovascular thrombectomy with best medical management for treating patients with acute basilar-artery occlusion. Condition being studied: Posterior circulation stroke (PCS) accounts for approximately a fifth of all strokes. As an important subtype of PCS, acute basilar artery occlusion is relatively rare, causing only 1% of all ischemic strokes and 5% of strokes due to large vessel occlusion. However, acute basilar artery occlusion is assosciated with poor outcomes, high risks of mortality and disability.
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Yang, Xingyu, Zilan Wang, Youjia Qiu, et al. Mechanical thrombectomy with intra-arterial alteplase provided better functional outcome for AIS-LVO: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0027.

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Zhang, Ziqu, Chenjin Wang, Wengang Xia, Jingwei Li, and Yali Wang. Efficacy and safety of Mechanical Thrombectomy for Cardioembolic Stroke: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.12.0035.

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Qiu, Youjia, Zilan Wang, Huiru Chen, et al. Direct endovascular thrombectomy versus bridging therapy in patients with posterior ischemic stroke: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0047.

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Bao, Qiangji, Xiaodong Huang, Pengxia Wang, et al. Safety and efficacy of intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and atrial fibrillation. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.9.0015.

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