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Books on the topic 'Thrombin inhibitor'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Claeson, Goran, Michael F. Scully, Vijay V. Kakkar, and John Deadman, eds. The Design of Synthetic Inhibitors of Thrombin. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2418-6.

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2

Burger, Christina F., Melissa L. Bellomy, and Joseph J. Schlesinger. Coagulation System. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0091.

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Anticoagulation is increasingly prevalent in the general population and poses a significant risk of increased bleeding in patients needing urgent or emergent surgical procedures. There are two main classes of direct or anticoagulants: direct thrombin inhibitors and factor Xa inhibitors. Management of these patients requires assessment of bleeding risk, possible reversal of anticoagulation, and subsequent management after surgery to prevent postoperative complications associated with either bleeding or clot formation (due to cessation of anticoagulants). This chapter covers the proper assessmen

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3

The Design of synthetic inhibitors of thrombin. Plenum Press, 1993.

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4

Scully, Michael F., Goran Claeson, Vijay V. Kakkar, and John Deadman. The Design of Synthetic Inhibitors of Thrombin. Springer, 2013.

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5

Struzebecher. Recent Developments in the Field of Thrombin Inhibitors: A special issue of the journal Enzyme Inhibition. Routledge, 1995.

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6

Buchanan, Michael R., Ph. D., Brister Stephanie J, and Ofosu Frederick A, eds. Thrombin: Its key role in thrombogenesis : implications for its inhibition clinically. CRC Press, 1995.

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7

(Editor), Goran Claeson, Michael F. Scully (Editor), Vijay V. Kakkar (Editor), and John Deadman (Editor), eds. The Design of Synthetic Inhibitors of Thrombin (Advances in Experimental Medicine and Biology). Springer, 1994.

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8

Capodanno, Davide. Bivalirudin and argatroban. Edited by Raffaele DeCaterina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0052.

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The central role of thrombin in the process of clot formation makes it an important therapeutic target. Heparin is a potent anticoagulant, but has a number of limitations, in that—for example—it does not bind clot-bound thrombin, activates platelets, and may determine heparin-induced thrombocytopenia (HIT). Bivalirudin and argatroban, which belong to the class of intravenous direct thrombin inhibitors, overcome many of the limitations of heparin. Bivalirudin is currently indicated for patients undergoing percutaneous coronary intervention, patients with non-ST-segment elevation acute coronary

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9

Ofosu, Frederick A., Stephanie J. Brister, and Michael R. Buchanan. ThrombinIts Key Role in Thrombogenesis-Implications for Its Inhibition. CRC, 1994.

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10

(Editor), H. K. Breddin, and J. M. Walenga (Editor), eds. Clinical Management of Thrombotic and Cardiovascular Disorders With Thrombin Inhibitors, the Role of Argatroban: The Role of Argatroban (Pathophysiology of Haemostasis and Thrombosis). Not Avail, 2003.

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11

Liying, Chen. Experimental Studies on Thrombosis and Thrombolysis: With Special Reference to Importance of Lys-Plasminogen, Active Site Thrombin Inhibitors and Stable ... Summaries of Uppsala Dissertations, 847). Uppsala Universitet, 1999.

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12

Oldgren, Jonas. Inflammation and Coagulation Activity in Unstable Coronary Artery Disease: And the Influences of Thrombin Inhibition (Comprehensive Summaries of Uppsala ... from the Faculty of Medicine, 1103). Uppsala Universitet, 2001.

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13

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0047.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following:All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hoursPatients with very high-risk non-ST-segment elevation acute coronary syndromes (recur

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14

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_001.

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Abstract:

Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following:All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hoursPatients with very high-risk non-ST-segment elevation acute coronary syndromes (recur

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15

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_002.

Full text

Abstract:

Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following: All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hours. Patients with very high-risk non-ST-segment elevation acute coronary syndromes (re

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16

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_003.

Full text

Abstract:

Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following: All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hours. Patients with very high-risk non-ST-segment elevation acute coronary syndromes (re

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