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Journal articles on the topic 'Thrombocytopenic Purpura'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Stein, Richard S. "Persistently Perplexing Purpuras: Thrombotic Thrombocytopenic Purpura and Immune Thrombocytopenic Purpura." Annals of Internal Medicine 121, no. 9 (1994): 720. http://dx.doi.org/10.7326/0003-4819-121-9-199411010-00019.

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2

Stricker, Raphael B. "Persistently Perplexing Purpuras: Thrombotic Thrombocytopenic Purpura and Immune Thrombocytopenic Purpura." Annals of Internal Medicine 121, no. 9 (1994): 720. http://dx.doi.org/10.7326/0003-4819-121-9-199411010-00031.

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3

Zucker-Franklin, Dorothea. "Persistently Perplexing Purpuras: Thrombotic Thrombocytopenic Purpura and Immune Thrombocytopenic Purpura." Annals of Internal Medicine 121, no. 9 (1994): 720. http://dx.doi.org/10.7326/0003-4819-121-9-199411010-00032.

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4

Schattner, Elaine. "Persistently Perplexing Purpuras: Thrombotic Thrombocytopenic Purpura and Immune Thrombocytopenic Purpura." Annals of Internal Medicine 121, no. 9 (1994): 720. http://dx.doi.org/10.7326/0003-4819-121-9-199411010-00033.

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5

., Alvina, and Diana Aulia. "IDIOPATHIC THROMBOCYTOPENIC PURPURA." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 16, no. 3 (2018): 149. http://dx.doi.org/10.24293/ijcpml.v16i3.1036.

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Idiopathic thrombocytopenic purpura is an autoimunne disease with low platelet count and bleeding manifestation like purpura, echymosis, petechie, mucosa membrane bleeding. The cause of ITP is platelet coated with specific thrombocyte autoantibody. Idiopathicthrombocytopenic purpura is classified as primary or secondary. The primary ITP is classified as acute and chronic.. Children and adultonset idiopathic thrombocytopenic purpura are different. An Acute ITP can be found in children and chronic onset can be found in adult.The duration of bleeding may help to distinguish acute and chronic idio

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6

Bennani Kenza, Tlamçani Imane, and Amrani Hassani Moncef. "Immune thrombocytopenic purpura in children: An update." World Journal of Advanced Research and Reviews 23, no. 2 (2024): 1456–61. http://dx.doi.org/10.30574/wjarr.2024.23.2.2485.

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Immune thrombocytopenic purpura, also known as Werlhof's disease, is the most common cause of thrombocytopenia in children. While the majority of childhood Immune thrombocytopenic purpura cases are benign and resolve spontaneously, a rigorous evaluation of bleeding potential using the Buchanan score remains essential. Indeed, in rare situations, the disease can progress to severe forms threatening life prognosis. The diagnosis of immune thrombocytopenic purpura relies on a combination of clinical, biological criteria, and exclusion of other causes of thrombocytopenia. Management of Immune thro

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7

Bennani, Kenza, Imane Tlamçani, and Hassani Moncef Amrani. "Immune thrombocytopenic purpura in children: An update." World Journal of Advanced Research and Reviews 23, no. 2 (2024): 1456–61. https://doi.org/10.5281/zenodo.14859400.

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Immune thrombocytopenic purpura, also known as Werlhof's disease, is the most common cause of thrombocytopenia in children. While the majority of childhood Immune thrombocytopenic purpura cases are benign and resolve spontaneously, a rigorous evaluation of bleeding potential using the Buchanan score remains essential. Indeed, in rare situations, the disease can progress to severe forms threatening life prognosis. The diagnosis of immune thrombocytopenic purpura relies on a combination of clinical, biological criteria, and exclusion of other causes of thrombocytopenia. Management of Immune thro

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8

Ge, Hangping, Zhan Shi, Zhiyin Zheng, et al. "Coexistence of thrombotic thrombocytopenic purpura and immune thrombocytopenic purpura in an Asian woman: a case report." Journal of International Medical Research 50, no. 3 (2022): 030006052210851. http://dx.doi.org/10.1177/03000605221085127.

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A 33-year-old Chinese woman with a history of immune thrombocytopenic purpura presented with heavy menstrual bleeding. She was found to have thrombocytopenia, plasma ADAMTS13 activity of 0%, and positivity for the plasma ADAMTS13 inhibitor. She was diagnosed with the coexistence of thrombotic thrombocytopenic purpura and immune thrombocytopenic purpura. The patient was treated by plasmapheresis, a glucocorticoid, and rituximab. Her platelet level returned to normal, and she was discharged 28 days after admission. The number of plasmapheresis sessions and the timing of rituximab administration

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Yalaz, Mehmet, Mehmet T. Arslan, and Zafer Kurugöl. "Thrombocytopenic purpura as only manifestation of brucellosis in a child." Turkish Journal of Pediatrics 46, no. 3 (2004): 265–67. http://dx.doi.org/10.24953/turkjped.2004.2815.

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Thrombocytopenic purpura associated with brucellosis has been rarely reported in the world literature. Thrombocytopenic purpura is generally part of the array of manifestations of brucellosis such as fever, arthritis, malaise and hepatosplenomegaly. We describe a nine-year-old girl who presented with thrombocytopenic purpura as the sole manifestation of brucellosis, which resolved with anti-Brucella chemotherapy. Her physical examination was remarkable for hepatomegaly of 3 cm and splenomegaly of 2 cm palpable below the costal margin. Initial laboratory investigations revealed isolated thrombo

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10

Dickey, Marcus SR, Anant J. Raina, Peter J. Gilbar, et al. "Pembrolizumab-induced thrombotic thrombocytopenic purpura." Journal of Oncology Pharmacy Practice 26, no. 5 (2019): 1237–40. http://dx.doi.org/10.1177/1078155219887212.

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Introduction Pembrolizumab is a humanised monoclonal antibody targeting the receptor programmed cell death protein-1 (PD-1), with anti-tumour activity demonstrated for many malignancies. Such immune checkpoint inhibitors are associated with many immune-related adverse events including rash, colitis, hepatitis, pneumonitis, endocrinopathy and, rarely, haematological adverse events, including immune-related thrombocytopenia. Case report We report a 60-year-old female with metastatic non-small cell lung cancer treated with pembrolizumab every three weeks. Following her fifth cycle, she presented

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11

Baldeo, Cherisse, Karan Seegobin, and Lara Zuberi. "Immune Thrombocytopenia as a Consequence of Rocky Mountain Spotted Fever." Case Reports in Oncology 10, no. 3 (2017): 945–47. http://dx.doi.org/10.1159/000481617.

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Primary immune thrombocytopenia (ITP) – also called idiopathic thrombocytopenic purpura or immune thrombocytopenic purpura – is an acquired thrombocytopenia caused by autoantibodies against platelet antigens. It is one of the more common causes of thrombocytopenia in otherwise asymptomatic adults. Rocky Mountain spotted fever (RMSF) is a potentially lethal, but curable, tick-borne disease. We present a case of ITP that was triggered by RMSF.

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12

Ellahi, Ayesha, Ayesha Nayyar, Maham Arshad, Wasiullah Khan, Afnan Naeem, and Warda Furqan. "Does Gestational Thrombocytopenia and Immune Thrombocytopenic Purpura Warrant Hospital Admission?" Pakistan Armed Forces Medical Journal 74, no. 2 (2024): 544–48. http://dx.doi.org/10.51253/pafmj.v74i2.9192.

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Objective: To determine the severity of thrombocytopenia in pregnancy and manage gestational thrombocytopenia patients in the outpatient department in order to reduce the economic burden on hospitals. Study Design: Cross-sectional study. Place and Duration of Study: Department of Haematology, Pakistan Railway Hospital, Rawalpindi, in collaboration with the Departments of Obstetrics and Gynaecology of Combined Military Hospital and Fauji Foundation Hospital, Rawalpindi, Pakistan from Oct 2018 to Oct 2019. Methodology: The sample population included ninety pregnant females with platelet count &l

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13

Aponte Barrios, Nelson Hernando, Adriana Linares Ballesteros, Isabel Cristina Sarmiento Urbina, and Gloria Inés Uribe Botero. "Evaluation of the diagnostic performance of platelet-derived indices for the differential diagnosis of thrombocytopenia in pediatrics." Revista de la Facultad de Medicina 62, no. 4 (2015): 547–52. http://dx.doi.org/10.15446/revfacmed.v62n4.43754.

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<p>Background. Platelet-derived indices have a well-established correlation with the differential diagnosis of thrombocytopenia in adult-based research. These indices include mean platelet volume, platelet distribution width, and platelet-large cell ratio.</p><p>Objective. To determine the values of platelet-derived indices in a pediatric population with diagnoses of thrombocytopenia and their etiologic correlation.</p><p>Materials and methods. Analytic observational diagnostictest study. The population for this analytical study was pediatric patients between 6 mo

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14

Xie, Xi, Ning Wang, Jingjing Xiang, Huadong He, Xuliang Wang, and Yuyong Wang. "Renal cell carcinoma associated with idiopathic thrombocytopenic purpura." International Journal of Immunopathology and Pharmacology 34 (January 2020): 205873842093161. http://dx.doi.org/10.1177/2058738420931619.

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We presented the clinical data of one patient with renal cell carcinoma associated with idiopathic thrombocytopenic purpura in this case report. We reported a 56-year-old man who presented with petechiae and ecchymoses. Laboratory studies showed the platelet count of 2 × 109/L and an abdominal computed tomography (CT) scan revealed tumors in the right renal. There were purpura on the legs and cough without abdominal pain and melena at this time. Idiopathic thrombocytopenic purpura was diagnosed according to the clinical symptoms and laboratory test. The patient received radical nephrectomy for

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15

Santivasi, Wil L., Meghan M. Routt, and Alicia M. Terando. "Idiopathic Thrombocytopenic Purpura after Mastectomy and Axillary Lymph Node Dissection." Case Reports in Surgery 2014 (2014): 1–2. http://dx.doi.org/10.1155/2014/316064.

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First described in 1916, idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease resulting in the destruction of platelets. Here, we present a case of an 85-year-old patient diagnosed with invasive ductal carcinoma of the breast whose surgical treatment was complicated postoperatively by acute-onset thrombocytopenia with a resultant hematoma at the operative site. Diagnostic Workup revealed no clear etiology for the thrombocytopenia; therefore, a presumptive diagnosis of idiopathic thrombocytopenic purpura was made. Previous literature has associated the development of idiopathic th

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16

Boğa, Can, and Muhsin Sırım. "Is Isolated Thrombocytopenia a Complication of Pregnancy." European Journal of Therapeutics 4, no. 1 (1993): 104–7. http://dx.doi.org/10.58600/eurjther.19930401-1151.

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Four pregnant woman with isolated thrombocytopenia were investigated. The first episode of the disease existed during pregnancy in 3 of 4 pregnant women with idiopathic thrombocytopenic purpura. Oinical remission was seen in only one patient after the pregnancy terminate. We conclude that pregnancy may aggravate the clinical course of idiopathic thrombocytopenic purpura.

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17

Komatsu, Norio. "1. Immune Thrombocytopenic Purpura (Immune Thrombocytopenia)." Nihon Naika Gakkai Zasshi 103, no. 7 (2014): 1593–98. http://dx.doi.org/10.2169/naika.103.1593.

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18

Özsoylu, Sinasi, Janine Campbell, and Christina Mitchell. "Autoimmune thrombocytopenia versus idiopathic thrombocytopenic purpura." European Journal of Haematology 53, no. 1 (2009): 54–55. http://dx.doi.org/10.1111/j.1600-0609.1994.tb00181.x.

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19

Tsitsikas, Dimitris A., Diana Mihalca, John Hall, et al. "Pitfalls in Diagnosing Thrombotic Thrombocytopenic Purpura in Sickle Cell Disease." Journal of Clinical Medicine 11, no. 22 (2022): 6676. http://dx.doi.org/10.3390/jcm11226676.

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Thrombotic thrombocytopenia purpura is characterised by microangiopathic haemolytic anaemia and red cell fragmentation on the peripheral smear, neurological involvement and thrombocytopenia. Diagnosis in the context of sickle cell disease can be challenging due to the inherent haemolytic state and the multitude of other associated complications of the latter. Specifically, fat embolism syndrome characterised by respiratory failure, neurological impairment and thrombocytopenia can be misdiagnosed this way. Confirmation of a diagnosis of thrombotic thrombocytopenic purpura requires demonstration

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20

Flessa, Herberct C. "Thrombocytopenic Purpura." Academic Emergency Medicine 2, no. 6 (1995): 573. http://dx.doi.org/10.1111/j.1553-2712.1995.tb03266.x.

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21

Odin, V. I., N. P. Lehthlaan-Thynisson, A. D. Zolotarev, N. V. Mineeva, and A. S. Polyakov. "Induction of the remission of immune thrombocytopenic purpura." Bulletin of the Russian Military Medical Academy 22, no. 3 (2020): 93–98. http://dx.doi.org/10.17816/brmma50541.

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Abstract. A review of the literature on remission of immune thrombocytopenic purpura in children and a retrospective analysis of its course in a young patient who was successively applied, first to no avail, standard drug therapy, and then, due to the lack of effect, a physiotherapy technique based on the principles of activation therapy. It is known that immune thrombocytopenic purpura is a rare acquired autoimmune disease characterized by isolated thrombocytopenia with the occurrence of hemorrhagic syndrome of varying severity, which can lead to fatal bleeding. At the same time, antiplatelet

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22

Guerra, João Carlos de Campos, Ruth Hissae Kanayama, Sonia Tsukasa Nozawa, et al. "Thrombocytopenia: diagnosis with flow cytometry and antiplatelet antibodies." Einstein (São Paulo) 9, no. 2 (2011): 130–34. http://dx.doi.org/10.1590/s1679-45082011ao1846.

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Objective: To identify antiplatelet antibodies by flow cytometry (direct method) in patients with thrombocytopenia. Methods: Between January 1997 and March 2004 a total of 15100 patients were referred to the Centro de Hematologia de São Paulo for hematological investigation of several diagnoses (anemia, leukopenia, thrombocytopenia, coagulation abnormalities, adenomegaly, leukemia and others). Of those, 1057 were referred because of thrombocytopenia and were divided into two groups: Group Idiopathic thrombocytopenic purpura, with no identifiable cause; and Group Other thrombocytopenia, which i

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23

Ellahi, Ayesha, Muhammad Wasiullah Khan, Samra Shahid, Javaid Usman, Hassan Ikran, and Safoora Naveed. "Thrombocytopenia in Pregnancy: A Cross-Sectional Study in Northern Pakistan." Pakistan Armed Forces Medical Journal 72, no. 3 (2022): 1013–17. http://dx.doi.org/10.51253/pafmj.v72i3.7048.

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Objective: To determine the association of thrombocytopenia (mild, moderate & severe) with pregnancy-related disorders. Study Design: Cross-sectional study. Place and Duration of Study: Department of Haematology of Pakistan Railway Hospital, Rawalpindi Pakistan, in collaboration with the Departments of Obstetrics and Gynecology of Pak Emirates Military Hospital and Fuji Foundation Hospital, Rawalpindi Pakistan, from Oct 2018 to Oct 2019. Methodology: Seventy-five pregnant females with platelet count <150x109/l were included. Blood samples were taken and analyzed for co

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24

Ezhilarasi, Ilamurugan, Karthiga Priyadharshini, N, Paramasivam Preethi, Shakila K.R, and Thalaimalai Saravanan. "Immune Thrombocytopenic Purpura – A Case Report and Narrative Review." Thai Moogambigai Journal Of Periodontics and Dental Science 2, no. 4 (2021): 80–82. http://dx.doi.org/10.37841/tmjpds_2021_v2_i4_03.

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An autoimmune bleeding disorder, formerly known as idiopathic thrombocytopenic purpura is characterized by isolated thrombocytopenia which is not associated with any other systemic illnesses. ITP in adults is often considered an autoimmune disorder, as the body produces antibodies that damage some of its own products-in this case, blood platelets. It is recorded that immune thrombocytopenic purpura occurs in about 2 in 1,00,000 adults. The course is more chronic although spontaneous remission can also occur within months of initial diagnosis. A thorough and timely workup of thrombocytopenia is

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25

Zotova, I. I., and S. V. Gritsaev. "Pathogenetic justification for the therapy of idiopathic thrombocytopenic purpura (primary immune thrombocytopenia) in adults." Kazan medical journal 99, no. 2 (2018): 279–86. http://dx.doi.org/10.17816/kmj2018-279.

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The review presents current data on key mechanisms of the pathogenesis of idiopathic thrombocytopenic purpura and comparative characteristics of main therapy methods. In recent years, the interest in studying this long known disease has significantly increased, and basic approaches to diagnosis and treatment have been revised. Recognition of the importance of immune-mediated mechanism of development of this disease led to the replacement of the term used for many years «idiopathic thrombocytopenic purpura» to «immune thrombocytopenia». Moreover, development of hemorrhagic manifestations (purpu

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26

Hassanain Elsayed, Yasser Mohammed. "COVID Pneumonia with Immune Thrombocytopenic Purpura and Some Novel Strange Graduated Electrocardiographic T-Wave Abnormalities, Clinical Impact and Interpretation." Asploro Journal of Biomedical and Clinical Case Reports 6, no. 1 (2023): 1–5. http://dx.doi.org/10.36502/2023/asjbccr.6281.

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Rationale: Immune thrombocytopenic purpura may be associated with severe acute respiratory syndrome (SARS) or Coronaviruses. Probably fatal outcome for the disease has a remarkable effect on morbidity and mortality. T-wave is the positive deflection post-each QRS-complex. Physiologically, it represents ventricular repolarization. Patient Concerns: A 66-year-old, teacher, married male, Egyptian patient was presented to the physician outpatient clinic with COVID-19 pneumonia with thrombocytopenia and abnormal T-wave. Diagnosis: COVID pneumonia with immune thrombocytopenic purpura and novel T-wav

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27

Skupski, Daniel W., and James B. Bussel. "Antenatal treatment of fetal immune thrombocytopenias." Fetal and Maternal Medicine Review 10, no. 1 (1998): 1–19. http://dx.doi.org/10.1017/s0965539598000114.

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Advances in both imaging techniques and in treatments for immune thrombocytopenias affecting the fetus have allowed for more accurate antenatal predictions of severe disease and effective antenatal treatments for those fetuses who are at risk of sequelae. This article will review current knowledge of the diagnosis and treatment of affected fetuses in alloimmune thrombocytopenia and in immune thrombocytopenic purpura.

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28

De Jesus Henriques, Leidy, Katherine Rosales Pereira, Diana De Oliveira-Gomes, Rocío Iglesias Fortes, and Erick Dávila Alcalá. "Púrpura trombocitopénica trombótica versus síndrome HELLP: reto diagnóstico en el embarazo." Revista de Obstetricia y Ginecología de Venezuela 81, no. 03 (2021): 292–96. http://dx.doi.org/10.51288/00810313.

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Worldwide, thrombocytopenia is one of the first causes of hematological alterations in pregnancy, affecting up to 10% of them. Despite the fact that all clinical entities with thrombocytopenia in pregnancy have a similar clinical spectrum, the distinction between them is vital to establish the appropriate treatment and thus reduce maternal-fetal morbidity and mortality. Purpura thrombotic thrombocytopenic is an infrequent disease, which despite not being linked to pregnancy, is not exempt from occurring in it, compared to HELLP syndrome, which is a multisystemic complication that occurs during

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29

Rajeswari, KS, M. Sivasundari, and D. Sithara. "Idiopathic Thrombocytopenic Purpura in Pregnancy." Journal of South Asian Federation of Obstetrics and Gynaecology 7, no. 2 (2015): 95–96. http://dx.doi.org/10.5005/jp-journals-10006-1334.

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ABSTRACT Idiopathic thrombocytopenic purpura (ITP) is a diagnosis of exclusion. It is an autoimmune disorder caused by development of IgG autoantibodies, directed against a number of platelet glycoproteins. A 26 years, primigravida, booked from 30 weeks of gestation, admitted at Sri Ramachandra Medical College and Hospital at 36 weeks of gestation, with gestational hypertension and severe thrombocytopenia with a platelet count of 45,000/mm3. She was treated with intravenous steroids during her antenatal period for thrombocytopenia. She delivered a healthy baby girl of weight 2.4 kg by cesarean

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30

Raj, Aswathi, Amina Asfiya, Malcolm Pinto, et al. "Hemorrhagic plaques in the oral cavity: A clue to diagnosing thrombocytopenia." Our Dermatology Online 12, no. 2 (2021): 166. http://dx.doi.org/10.7241/ourd.20212.14.

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Idiopathic thrombocytopenic purpura is a disorder with a myriad of possible clinical presentations. The mechanism of thrombocytopenia involves both increased platelet destruction and impaired platelet production. The patient can manifest a wide range of symptoms: from asymptomatic or minimal gingival bleeding to profuse bleeding from any site. The disease may first present itself to the dermatologist in cutaneous findings such as petechiae, purpura, and mucosal manifestations in the form of gingival bleeding and hemorrhagic bullae. The diagnosis of idiopathic thrombocytopenic purpura is mostly

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31

Galstyan, G. M., E. E. Klebanova, S. Yu Mamleeva, et al. "Immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura — diagnostic difficulties and errors." Russian journal of hematology and transfusiology 68, no. 3 (2023): 317–34. http://dx.doi.org/10.35754/0234-5730-2023-68-3-317-334.

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Introduction. When establishing a diagnosis of thrombotic thrombocytopenic purpura (TTP) for the first time, other diseases occurring with thrombocytopenia may be misdiagnosed. Aim: to analyze diagnostic difficulties and errors of TTP. Materials and methods. In total, 54 patients (44 women and 10 men) aged 18 to 83 years (median 33 years), who were diagnosed TTP from 2019 to 2023, were included in the study. Anamnesis, baseline hemoglobin, platelets, erythrocytes, lactate dehydrogenase and bilirubin serum concentrations, pre-established diagnoses, treatment, and outcomes were analyzed. Results

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32

Zaher, Galila F., and Maha A. Badawi. "Heparin-Induced Thrombocytopenia Complicating Thrombotic Thrombocytopenic Purpura." Journal of King Abdulaziz University - Medical Sciences 24, no. 1 (2017): 43–48. http://dx.doi.org/10.4197/med.24-1.5.

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Since the introduction of therapeutic plasma exchange for the management of thrombotic thrombocytopenic purpura, the prognosis of this disease improved signifi cantly. Some patients suffer from refractory disease and adjunctive therapy needs to be considered. In addition, alternative explanations for thrombocytopenia may bepresent. In this report we discuss a patient who presented with typical fi ndings of thrombotic thrombocytopenic purpura and responded initially to therapeutic plasma exchange and steroids. Shortlyafterwards, his platelet count deteriorated and he was found to have acute pul

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Deepika, Modi, Kumar Bhimani Rippal, A. Kanasagara Anandkumar, Patel Shailesh, and Modi Jayesh. "The Significance of Immature Platelet Fraction in the Diagnosis and Prognosis of Groups with Thrombocytopenia." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 363–67. https://doi.org/10.5281/zenodo.11215108.

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<strong>Background and Aim: </strong>Accelerated platelet breakdown and decreased platelet synthesis are major causes of thrombocytopenia in immune thrombocytopenic purpura (ITP). In our study, thrombocytopenia instances were classified as hypoproductive, megaloblastic, or hyperdestructive. Our study aims to assess the prevalence of IPF and its importance in various thrombocytopenic groups, with the hope that it can be used as a new emerging prognostic marker in identifying and managing such patients. <strong>Material and Methods:</strong> 50 thrombocytopenia samples were collec

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Albagshi, MuneerHassan, AbbasM Al Omran, and HebaA Elhakeem. "Congenital thrombotic thrombocytopenic purpura simulating alloimmune thrombocytopenia." Journal of Clinical Neonatology 11, no. 4 (2022): 224. http://dx.doi.org/10.4103/jcn.jcn_63_22.

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35

Generali, Joyce A., and Dennis J. Cada. "Rituximab: Primary Immune Thrombocytopenia (Idiopathic Thrombocytopenic Purpura)." Hospital Pharmacy 46, no. 4 (2011): 251–53. http://dx.doi.org/10.1310/hpj4604-251.

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36

Zimmer, Jacques, François Hentges, and Emmanuel Andres. "Borderline Thrombocytopenia or Mild Idiopathic Thrombocytopenic Purpura?" PLoS Medicine 3, no. 8 (2006): e362. http://dx.doi.org/10.1371/journal.pmed.0030362.

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SHAN UL ABEDIN, MUHAMMAD, and IZZA BATOOL. "IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA WITHOUT THROMBOCYTOPENIA." CHEST 166, no. 4 (2024): A2929—A2930. http://dx.doi.org/10.1016/j.chest.2024.06.1766.

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38

Kaneko, Ryota, Shohei Yamamoto, Naoko Okamoto, et al. "Wiskott–Aldrich syndrome that was initially diagnosed as immune thrombocytopenic purpura secondary to a cytomegalovirus infection." SAGE Open Medical Case Reports 6 (January 1, 2018): 2050313X1775378. http://dx.doi.org/10.1177/2050313x17753788.

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Wiskott–Aldrich syndrome is a rare X-linked recessive disease resulting from variations in the WAS gene. Wiskott–Aldrich syndrome is sometimes difficult to differentiate from immune thrombocytopenic purpura. A 2-month-old boy was admitted to our hospital for purpura and thrombocytopenia. His mean platelet volume was reported to be normal. Treatment with intravenous immunoglobulins failed to improve the patient’s platelet count. Subsequently, an acute cytomegalovirus infection was confirmed by serological testing and antigenemia. The patient was diagnosed with immune thrombocytopenic purpura se

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Shelat, Suresh G. "Thrombotic Thrombocytopenic Purpura and Sickle Cell Crisis." Clinical and Applied Thrombosis/Hemostasis 16, no. 2 (2008): 224–27. http://dx.doi.org/10.1177/1076029608323804.

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Described is a case of acute chest syndrome in a sickle-cell patient (hemoglobin SS) who also developed signs and symptoms of thrombotic thrombocytopenic purpura, including thrombocytopenia and hemolysis (anemia, elevated lactate dehydrogenase, presence of schistocytes, dark-colored plasma, and elevations in nucleated red blood cells). The ADAMTS13 activity level was normal. Discussed are the diagnosis and therapeutic management issues and the challenges of differentiating the vasoocclusive and hemolytic complications of sickling red blood cells from the thrombotic microangiopathy of thromboti

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Dias, Ana Tânia Pereira, Sidrayton Pereira Do Nascimento, Idernon Cândido Nascimento, et al. "IDIOPATHIC (AUTOIMMUNE) THROMBOCYTOPENIC PURPURA: A CASE REPORT." REVISTA FOCO 17, no. 2 (2024): e4349. http://dx.doi.org/10.54751/revistafoco.v17n2-015.

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This report aims to describe a school patient, from the city of Juazeiro da Bahia, diagnosed with idiopathic thrombocytopenic purpura (autoimmune) and diagnosed with thrombocytopenia that had been sustained for months. Initially, he was diagnosed with dengue and anemia. Although this report describes a patient's favorable evolution, the relevance of carrying out future studies to evaluate the effects of thrombocytopenic purpura is highlighted. In short, this study aims to reference the most common findings through scientific literature as well as signs of worsening.

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Shani, Marsela, and Drita Jaka GP. "Idiopathic thrombocytopenic purpura in tuberculosis (Case Report)." Journal of Clinical Case Reports & Studies 3, no. 8 (2022): 01–03. http://dx.doi.org/10.31579/2690-8808/121.

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Tuberculosis (TB) is a contagious disease in both developing and developed countries. The incidence is increasing due to bacilli resistant to many drugs and the human immunodeficiency virus (HIV). Since 2012, India has the highest incidence of the disease at around 2.2 million cases, accounting for 26% of the global incidence according to World Health Organization statistics. A wide range of hematological manifestations is observed in TB, where thrombocytopenia is common in miliary TB and thrombocytosis in pulmonary TB. Immune thrombocytopenic purpura (ITP) is characterized by a low platelet c

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Grigoreva, K. N., N. D. Degtyareva, N. R. Gashimova, et al. "Thrombotic thrombocytopenic purpura in newborns." Voprosy ginekologii, akušerstva i perinatologii 23, no. 4 (2024): 107–14. https://doi.org/10.20953/1726-1678-2024-4-107-114.

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Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder leading to severe thrombocytopenia, microangiopathic hemolytic anemia, and target organ microthrombosis. Recently, there has been increasing evidence on the functioning of ADAMTS13 metalloproteinase and von Willebrand factor during normal and pathological pregnancy, COVID-19 pandemic, etc. However, in the neonatal period, TTP is characterized by the absence of “typical” clinical presentation. Most symptoms correlate with other diseases, making diagnosis difficult. Only early diagnosis and treatment of TTP can save t

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Al-Nabolsi, A., V. Tripathi, G. Darany, and O. Khan. "Immune Thrombocytopenic Purpura: A Case of Risperidone-induced Immune Thrombocytopenia Purpura." American Journal of Respiratory and Critical Care Medicine 211, Abstracts (2025): A5543. https://doi.org/10.1164/ajrccm.2025.211.abstracts.a5543.

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Nwagu, Marcellinus Uchechukwu. "Successful treatment of a patient with herbal drug-induced immune thrombocytopenic purpura using freshly donated blood." Universa Medicina 37, no. 3 (2018): 222. http://dx.doi.org/10.18051/univmed.2018.v37.222-226.

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Background<br />Drug-induced thrombocytopenia (DITP), which also includes thrombocytopenia induced by beverages, foods, and herbal remedies, is an important clinical problem for haematologists. Drug-induced thrombocytopenia is often misdiagnosed as immune thrombocytopenic purpura with resulting inappropriate treatment. Immune thrombocytopenic purpura (ITP) is a clinical disorder that leads to easy bruising (purpura), excessive bleeding or extravasation of blood from capillaries into skin and mucous membranes (petechiae). The bleeding tendency is due to decreased number of circulating pla

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Birkhoelzer, Sarah, Alexandra Belcher, and Helen Peet. "Diagnostic dilemma: Severe thrombotic microangiopathy in pregnancy." Journal of the Intensive Care Society 18, no. 4 (2017): 348–51. http://dx.doi.org/10.1177/1751143717715969.

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A diagnostic dilemma occurred when thrombotic microangiopathy developed during pregnancy. The diagnostic criteria of thrombotic microangiopathy include thrombocytopenia (platelets <100) and microangiopathic haemolytic anaemia (including thrombotic thrombocytopenic purpura and haemolytic-uraemic syndrome). An urgent interdisciplinary approach is required to treat thrombotic microangiopathy in pregnancy to differentiate between thrombotic microangiopathy and HELLP syndrome (haemolysis, elevated liver enzymes, low platelets).1 This case presented with the pentad of thrombotic thrombocytopenic

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Nikolaou, Marinos, Marina Karakantza, George Adonakis, George Theodorou, Nikolaos Zoumbos, and George Decavalas. "A case of severe ADAMTS 13 deficiency presenting as thrombotic thrombocytopenic purpura in pregnancy." Medical review 65, no. 9-10 (2012): 436–39. http://dx.doi.org/10.2298/mpns1210436n.

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Introduction. Thrombotic thrombocytopenic purpura is a rare lifethreatening disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia. It is caused by the absent or severe deficiency of the von Willebrand Factor-cleaving protease named ADAMTS13. Pregnancy is a well recognized factor precipitating the appearance of the disease both in women that had reduced levels of ADAMTS13 activity prior to gestation and in those with other inherited or acquired thrombophilic syndromes. Case Report. We report a 25-year old woman with severe ADAMTS13 deficiency presented early in her 1s

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Haider, Mohammad Shabih, Asad Mahmood, Manzar Bozdar, Saima Zahir, Saadia Muzafar, and Maliha Batool Bukhari. "Significance of Immature Platelet Fraction in Diagnosed Patients of the Immune Thrombocytopenic Purpura." Pakistan Armed Forces Medical Journal 72, no. 4 (2022): 1420–23. http://dx.doi.org/10.51253/pafmj.v72i4.8376.

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Objective: Determination of significance of immature platelet fraction (IPF%) in diagnosed patients of Immune thrombocytopenic purpura (ITP). Study Design: It was a cross-sectional study. Place and Study Duration: Haematology department, Armed forces Institute of Pathology (AFIP), Rawalpindi Pakistan June 2021 to December 2021. Methodology: Patients of all ages and genders diagnosed with ITP and platelets less than 100 x 109/L after a review of peripheral blood film were included in the study. Detailed history and examination were made, complete blood count (CBC) test was don

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KUWANA, Masataka. "Idiopathic thrombocytopenic purpura." Japanese Journal of Thrombosis and Hemostasis 19, no. 2 (2008): 199–201. http://dx.doi.org/10.2491/jjsth.19.199.

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Lloyd-Puryear, M. A., G. S. Evans, and T. E. Balbier. "Recurrent Thrombocytopenic Purpura." PEDIATRICS 99, no. 3 (1997): 499. http://dx.doi.org/10.1542/peds.99.3.499.

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Chu, Y. W., J. Korb, and K. M. Sakamoto. "Idiopathic Thrombocytopenic Purpura." Pediatrics in Review 21, no. 3 (2000): 95–104. http://dx.doi.org/10.1542/pir.21-3-95.

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