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1

K, MacCallum P., and Meade T. W, eds. Thrombophilia. Baillière Tindall, 1999.

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2

W, Meade T., ed. Thrombophilia. Baillière Tindall, 1994.

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3

Benjamin, Brenner, ed. Thrombophilia in pregnancy. Baillière Tindall, 2003.

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4

Benjamin, Brenner, ed. Thrombophilia in pregnancy. Baillière Tindall, 2003.

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5

Lockwood, Charles J. Thrombosis, thrombophilia and thromboembolism. American College of Obstetricians and Gynecologists, 2007.

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6

Dorgalaleh, Akbar, and Anvarjon Samadov, eds. Laboratory Investigations of Thrombophilia. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-90986-3.

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7

Z, Goldhaber Samuel, and Ridker Paul M. 1959-, eds. Thrombosis and thromboembolism. M. Dekker, 2002.

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8

J, Seghatchian M., Samama Meyer M, and Hecker S. P, eds. Hypercoagulable states: Fundamental aspects, acquired disorders, and congenital thrombophilia. CRC Press, 1996.

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9

R, Higgins J., and Brennecke S. P, eds. Inherited thrombophilias. Baillière Tindall, 2003.

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10

Benjamin, Brenner, Marder Victor J, and Conard Jacqueline, eds. Women's issues in thrombosis and hemostasis. Martin Dunitz, 2002.

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11

Oehm, Horst. Antithrombin III: Seine bedeutung für die Therapie der Verbrauchskoagulopathie und die Wertigkeit der Antithrombin-III-Spiegelbestimmungen [Antithrombin-Spiegelbestimmungen] in der Diagnostik thrombophiler Zustände. [s.n.], 1987.

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12

Tranquilli, Andrea, ed. Thrombophilia. InTech, 2011. http://dx.doi.org/10.5772/1329.

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13

Thrombophilia (Bailliere's Clinical Haematology). Elsevier, 1994.

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14

Ridker, Paul M., and Samuel Z. Goldhaber. Thrombosis and Thromboembolism. Taylor & Francis Group, 2001.

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15

Ridker, Paul M., and Samuel Z. Goldhaber. Thrombosis and Thromboembolism. Taylor & Francis Group, 2019.

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16

Ridker, Paul M., and Samuel Z. Goldhaber. Thrombosis and Thromboembolism. Taylor & Francis Group, 2001.

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17

Ivanov, Petar, ed. Pregnancy Thrombophilia - The Unsuspected Risk. InTech, 2013. http://dx.doi.org/10.5772/46070.

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18

(Editor), M. J. Seghatchian, Samama M. M. (Editor), and S. P. Hecker (Editor), eds. Hypercoagulable States: Fundamental Aspects, Acquired Disorders, and Congenital Thrombophilia. CRC Press, 1996.

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19

(Editor), Samuel Z. Goldhaber, and Paul M. Ridker (Editor), eds. Thrombosis and Thromboembolism (Fundamental and Clinical Cardiology). Informa Healthcare, 2001.

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20

Ridker, Paul M., and Samuel Z. Goldhaber. Thrombosis and Thromboembolism. Taylor & Francis Group, 2001.

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21

Thrombophilia & Women's Health, An Issue of Obstetrics and Gynecology Clinics. Saunders, 2006.

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22

Alikhan, Raza. Prothrombotic conditions. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0285.

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The term thrombophilia is used to describe an individual who has a tendency to develop thrombosis. Arterial thrombosis is usually linked with classical risk factors such as age, smoking, hypertension, hyperlipidaemia, or diabetes; a thrombophilia assessment and workup is not usually considered in cases of arterial thrombosis. A clinically useful approach to the diagnosis and management of a patient with a venous thrombotic process is to categorize the disorder as either a primary (inherited) or secondary (acquired) hypercoagulable state. This topic addresses the diagnosis and management of pro
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23

Hvas, Anne-Mette, Erik L. Grove, and Steen Dalby Kristensen. Biomarkers of coagulation and thrombosis. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0038.

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Coagulation is evaluated by conventional coagulation analyses, often supplemented by point-of-care tests. Recently, a number of point-of-care tests for evaluation of platelet function and the efficacy of antiplatelet therapy has been investigated. Thrombophilia contributes to the risk of thrombosis, and a battery of complex assays is required to identify all thrombophilias. Disseminated intravascular coagulation is characterized by microthrombosis and clinical bleeding. A scoring system for overt disseminated intravascular coagulation provides a five-step diagnostic algorithm. The cornerstone
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24

Hvas, Anne-Mette, Erik L. Grove, and Steen Dalby Kristensen. Biomarkers of coagulation and thrombosis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0038_update_001.

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Coagulation is evaluated by conventional coagulation analyses, often supplemented by point-of-care tests. Recently, a number of point-of-care tests for evaluation of platelet function and the efficacy of antiplatelet therapy has been investigated. Thrombophilia contributes to the risk of thrombosis, and a battery of complex assays is required to identify all thrombophilias. Disseminated intravascular coagulation is characterized by microthrombosis and clinical bleeding. A scoring system for overt disseminated intravascular coagulation provides a five-step diagnostic algorithm. The cornerstone
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25

Provan, Drew, Trevor Baglin, Inderjeet Dokal, and Johannes de Vos. Haemostasis and thrombosis. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199683307.003.0010.

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Assessing haemostasis - The coagulation system - Laboratory tests - Platelets - Bleeding - Bleeding: laboratory investigations - Bleeding: therapeutic products - von Willebrand disease - Haemophilia A and B - Rare congenital coagulation disorders - Congenital thrombocytopenias - Congenital platelet function defects - Congenital vascular disorders - Haemorrhagic disease of the newborn - Thrombocytopenia (acquired) - Specific thrombocytopenic syndromes - Disseminated intravascular coagulation - Liver disease - Renal disease - Acquired anticoagulants and inhibitors - Treatment of spontaneous FVII
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26

Provan, Drew, Trevor Baglin, Inderjeet Dokal, Johannes de Vos, and Angela Theodoulou. Haemostasis and thrombosis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199683307.003.0010_update_001.

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Assessing haemostasis - The coagulation system - Laboratory tests - Platelets - Bleeding - Bleeding: laboratory investigations - Bleeding: therapeutic products - von Willebrand disease - Haemophilia A and B - Rare congenital coagulation disorders - Congenital thrombocytopenias - Congenital platelet function defects - Congenital vascular disorders - Haemorrhagic disease of the newborn - Thrombocytopenia (acquired) - Specific thrombocytopenic syndromes - Disseminated intravascular coagulation - Liver disease - Renal disease - Acquired anticoagulants and inhibitors - Treatment of spontaneous FVII
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27

Fox, Grenville, Nicholas Hoque, and Timothy Watts. Nephrological and urological problems. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198703952.003.0015.

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This chapter gives a brief overview of haemopoiesis and describes common haematological problems in the newborn period, with practical evidence-based guidance to investigation (including coagulation screening) and treatment. Topics include anaemia, haemolytic disease of the newborn, polycythaemia, neutropenia, and thrombocytopenia. An overview of clotting problems includes haemophilias, vitamin K dependent bleeding, thrombophilia and thrombosis.
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28

Schramm, Wolfgang, and Inge Scharrer. 26. Hämophilie-Symposion: H.I.V.-Infektion, Sicherheit von Faktorenkonzentraten, Hämophilie-Therapie, Pädiatrie, Thrombophilie, Thrombophile Diathese, ... Diathese, Kasuistiken. Springer, 1996.

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29

Schramm, Wolfgang, and Inge Scharrer. 26. Hämophilie-Symposion: HIV-Infektion, Sicherheit Von Faktorenkonzentraten, Hämophilie-Therapie, Pädiatrie, Thrombophilie, Thrombophile Diathese, Hämorrhagische Diathese, Kasuistiken. Springer London, Limited, 2013.

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30

Yurdakul, Sebahattin, Emire Seyahi, and Hasan Yazici. Behçet’s syndrome. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0135.

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Behçet's syndrome is a systemic inflammatory panvasculitis (affecting all sizes of vessels) of unknown aetiology. It is in vogue to include it among the systemic autoinflammatory conditions. Behçet's syndrome is more frequent along the ancient 'Silk Route' across Asia than it is in Western countries. The usual onset is the second or third decade, equally affecting either gender. However, young patients and male patients have more severe disease. Almost all patients have recurrent oral ulceration. Scar-forming genital ulcers, a variety of skin lesions including acneiform, erythema nodosum-like
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31

Carton, James. Haematopathology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198759584.003.0015.

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This chapter discusses haematopathology, including iron deficiency anaemia, anaemia of chronic disease, megaloblastic anaemias, hereditary spherocytosis, glucose-6-phosphate dehydrogenase deficiency, thalassaemias, sickle-cell disorders, idiopathic thrombocytopenic purpura (ITP), thrombotic thrombocytopenic purpura (TTP), von Willebrand disease, haemophilia, thrombophilia, acute B-lymphoblastic leukaemia, acute myeloid leukaemias, chronic lymphocytic leukaemia (CLL), chronic myelogenous leukaemia, polycythaemia vera (PV), essential thrombocythaemia (ET), primary myelofibrosis (PMF), myelodyspl
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32

Chung, Melissa, and Warren Lo. Pediatric Stroke. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0106.

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A variety of congenital and genetic disorders not seen frequently in adults may be responsible for stroke in infants and children. Stroke in newborn infants is as common as stroke in elderly individuals due to risk factor such as congenital heart disease, thrombophilia associated with polycythemia in neonates and genetic disorders, high estrogen impact from the mother during pregnancy, and inflammation due to infections. Stroke can also be caused by genetic disorders such as Ehleers-Danlos syndrome, Sturge-Weber syndrome, and vasculopathies such as lupus and fibromuscular dysplasia. Arterial d
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33

Poretti, Andrea, and Michael V. Johnston. Genetic Disorders and Stroke. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0110.

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A variety of monogenic and polygenic genetic disorders have been linked to stroke, making it important for the clinician to keep up with the new discoveries and the potential to provide new gene-based therapies. Hematologic disorders such as sickle cell disease and thrombophilia due to mutations in prothrombin, factor V Leiden, and homocysteine metabolism are fairly well known, but mutations in mitochondrial metabolism and matrix metalloproteinases are less recognized. In addition, results of genome-wide association studies (GWAS) in stroke populations are revealing mutations that could predis
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34

Ballal, Salma, and Ian A. Greer. Thromboembolic disorders in pregnancy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0037.

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Thromboembolism in pregnancy remains a major cause of direct maternal mortality in the Western world. Thromboembolic events in pregnancy are spread across the three trimesters but the puerperium is the time of greatest risk with a relative risk of around 20-fold compared to the non-pregnant patient. When compared to the non-pregnant population where distal deep vein thrombosis is most common, most events in pregnancy are iliofemoral and left sided. Given the multi-hit nature of the problem, awareness of risk factors is important. The two most significant single risk factors in pregnancy for th
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35

Acute Pulmonary Embolism: A Challenge for Hemostasiology. Steinkopff-Verlag Darmstadt, 2000.

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36

Putaala, Jukka, and Nicolas Martinez-Majander. Risk factors. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198722366.003.0002.

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Risk factors in young-onset stroke include both traditional and unconventional as well as both chronic and temporal ones. In young patients, unconventional risk factors such as oral contraceptive use, antiphospholipid antibodies, genetic thrombophilia, acute infections, illicit drug use, and migraine may play a greater role than in elderly patients. However, recent large studies have challenged this traditional view suggesting that young adult stroke would occur mostly due to such unconventional risk factors. These studies have shown a high prevalence of in particular modifiable behavioural ri
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37

Marder, Victor J., Benjamin Brenner, and Jacqueline Conard. Women's Issues in Thrombosis and Hemostasis. Taylor & Francis Group, 2002.

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38

(Editor), Benjamin Brenner, Victor J. Marder (Editor), and Jacqueline Conard (Editor), eds. Women's Issues in Thrombosis and Hemostasis. Informa Healthcare, 2002.

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39

Marder, Victor J., Benjamin Brenner, and Jacqueline Conard. Women's Issues in Thrombosis and Hemostasis. Taylor & Francis Group, 2004.

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40

Ladik, Tristan. Untersuchungen zur Thrombophilen Diathese des Diabetes mellitus. 1988.

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41

Olson, John D., Steve Kitchen, and F. Eric Preston. Quality in Laboratory Hemostasis and Thrombosis. Wiley & Sons, Incorporated, John, 2013.

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42

Olson, John D., Steve Kitchen, F. Eric Preston, and Frits R. Rosendaal. Quality in Laboratory Hemostasis and Thrombosis. Wiley & Sons, Incorporated, John, 2011.

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43

Olson, John D., Steve Kitchen, and F. Eric Preston. Quality in Laboratory Hemostasis and Thrombosis. Wiley & Sons, Limited, John, 2013.

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44

Olson, John D., Steve Kitchen, and F. Eric Preston. Quality in Laboratory Hemostasis and Thrombosis. Wiley & Sons, Incorporated, John, 2013.

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45

Olson, John D., Steve Kitchen, F. Eric Preston, and Frits R. Rosendaal. Quality in Laboratory Hemostasis and Thrombosis. Wiley & Sons, Incorporated, John, 2011.

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46

Olson, John D., Steve Kitchen, and F. Eric Preston. Quality in Laboratory Hemostasis and Thrombosis. Wiley & Sons, Incorporated, John, 2013.

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47

Quality in Laboratory Hemostasis and Thrombosis. Wiley-Blackwell, 2013.

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48

Scharrer, I. 23. Hamophilie-Symposion Hamburg 1992: Hiv-Infektion, Hiv-Assoziierte Neurologische Studien, Hamophilie Des Kniegelenkes, Thrombophilie. Springer-Verlag, 1993.

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49

Schramm, Wolfgang, and Inge Scharrer. 28. Hämophilie-Symposion Hamburg 1997 : Verhandlungsberichte : Virusinfektion Synovitis ― Pathogenese und Behandlung Thrombophilie: Prothrombinmutation ... Hämostaseologie Kasuistiken. Springer, 1998.

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50

Zimmermann, R., H. Beeser, G. Landbeck, et al. 22. Hämophilie-Symposion Hamburg 1991 : Verhandlungsberichte: Frühe Interventionstherapie bei HIV-infizierten Hämophilen; Psychosoziale Betreuung ... Thrombophilie. Springer, 1992.

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